JBC -- Table of Contents (Mar 25 2005, 280, (12))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Launching the Age of Biochemical Genetics, with Neurospora: the Work of George Wells Beadle
AN INOSITOLLESS MUTANT STRAIN OF NEUROSPORA AND ITS USE IN BIOASSAYS (G. W. Beadle J. Biol. Chem. 156, 683-690)
J. Biol. Chem. 2005 280: e9. [Full Text]

Minireviews:

Jean E. Vance and Dennis E. Vance: Metabolic Insights into Phospholipid Function Using Gene-targeted Mice
J. Biol. Chem. 2005 280: 10877-10880. First Published on January 10, 2005; doi:10.1074/jbc.R400038200 [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Guylaine Haché, Mark T. Liddament, and Reuben S. Harris: The Retroviral Hypermutation Specificity of APOBEC3F and APOBEC3G Is Governed by the C-terminal DNA Cytosine Deaminase Domain
J. Biol. Chem. 2005 280: 10920-10924. First Published on January 12, 2005; doi:10.1074/jbc.M500382200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Diane E. Grove, Smaranda Willcox, Jack D. Griffith, and Floyd R. Bryant: Differential Single-stranded DNA Binding Properties of the Paralogous SsbA and SsbB Proteins from Streptococcus pneumoniae
J. Biol. Chem. 2005 280: 11067-11073. First Published on January 12, 2005; doi:10.1074/jbc.M414057200 [Abstract] [Full Text] [PDF]

Aaron J. Oakley, Karin V. Loscha, Patrick M. Schaeffer, Edvards Liepinsh, Guido Pintacuda, Matthew C. J. Wilce, Gottfried Otting, and Nicholas E. Dixon: Crystal and Solution Structures of the Helicase-binding Domain of Escherichia coli Primase: o
J. Biol. Chem. 2005 280: 11495-11504. First Published on January 12, 2005; doi:10.1074/jbc.M412645200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jerrylaine Vaughn, Shengli Huang, Irene Wessel, Tina K. Sorensen, Tao Hsieh, Lars H. Jensen, Peter B. Jensen, Maxwell Sehested, and John L. Nitiss: Stability of the Topoisomerase II Closed Clamp Conformation May Influence DNA-stimulated ATP Hydrolysis
J. Biol. Chem. 2005 280: 11920-11929. First Published on January 12, 2005; doi:10.1074/jbc.M411841200 [Abstract] [Full Text] [PDF]

Lyuben Tsvetkov and David F. Stern: Interaction of Chromatin-associated Plk1 and Mcm7
J. Biol. Chem. 2005 280: 11943-11947. First Published on January 15, 2005; doi:10.1074/jbc.M413514200 [Abstract] [Full Text] [PDF]

Kelly S. Colletti, Yiyang Xu, Irena Yamboliev, and Gregory S. Pari: Human Cytomegalovirus UL84 Is a Phosphoprotein That Exhibits UTPase Activity and Is a Putative Member of the DExD/H Box Family of Proteins
J. Biol. Chem. 2005 280: 11955-11960. First Published on February 1, 2005; doi:10.1074/jbc.C400603200 [Abstract] [Full Text] [PDF]

Jia Li and David F. Stern: Regulation of CHK2 by DNA-dependent Protein Kinase
J. Biol. Chem. 2005 280: 12041-12050. First Published on January 24, 2005; doi:10.1074/jbc.M412445200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Ying Wang and Honglin Jiang: Identification of a Distal STAT5-binding DNA Region That May Mediate Growth Hormone Regulation of Insulin-like Growth Factor-I Gene Expression
J. Biol. Chem. 2005 280: 10955-10963. First Published on January 27, 2005; doi:10.1074/jbc.M412808200 [Abstract] [Full Text] [PDF]

Leonard C. Edelstein, Amy Pan, and Tucker Collins: Chromatin Modification and the Endothelial-specific Activation of the E-selectin Gene
J. Biol. Chem. 2005 280: 11192-11202. First Published on January 25, 2005; doi:10.1074/jbc.M412997200 [Abstract] [Full Text] [PDF]

Yukiko Imazawa, Koji Hisatake, Hiroshi Mitsuzawa, Masahito Matsumoto, Tohru Tsukui, Kaori Nakagawa, Tomoyoshi Nakadai, Miho Shimada, Akira Ishihama, and Yasuhisa Nogi: The Fission Yeast Protein Ker1p Is an Ortholog of RNA Polymerase I Subunit A14 in Saccharomyces cerevisiae and Is Required for Stable Association of Rrn3p and RPA21 in RNA Polymerase I
J. Biol. Chem. 2005 280: 11467-11474. First Published on January 12, 2005; doi:10.1074/jbc.M411150200 [Abstract] [Full Text] [PDF]

Lior Appelbaum, Ana Anzulovich, Ruben Baler, and Yoav Gothilf: Homeobox-Clock Protein Interaction in Zebrafish: A SHARED MECHANISM FOR PINEAL-SPECIFIC AND CIRCADIAN GENE EXPRESSION
J. Biol. Chem. 2005 280: 11544-11551. First Published on January 18, 2005; doi:10.1074/jbc.M412935200 [Abstract] [Full Text] [PDF]

Kevin Chen, Xiao-Ming Ou, Gao Chen, Si Ho Choi, and Jean C. Shih: R1, a Novel Repressor of the Human Monoamine Oxidase A
J. Biol. Chem. 2005 280: 11552-11559. First Published on January 14, 2005; doi:10.1074/jbc.M410033200 [Abstract] [Full Text] [PDF]

Chantelle D. Hudson, Peter J. Morris, David S. Latchman, and Vishwanie S. Budhram-Mahadeo: Brn-3a Transcription Factor Blocks p53-mediated Activation of Proapoptotic Target Genes Noxa and Bax in Vitro and in Vivo to Determine Cell Fate
J. Biol. Chem. 2005 280: 11851-11858. First Published on December 13, 2004; doi:10.1074/jbc.M408679200 [Abstract] [Full Text] [PDF]

Li Zhao, Min Guo, Taka-aki Matsuoka, Derek K. Hagman, Susan D. Parazzoli, Vincent Poitout, and Roland Stein: The Islet ${beta}$ Cell-enriched MafA Activator Is a Key Regulator of Insulin Gene Transcription
J. Biol. Chem. 2005 280: 11887-11894. First Published on January 20, 2005; doi:10.1074/jbc.M409475200 [Abstract] [Full Text] [PDF]

Ayako Yamamoto, Yu Mizukami, and Hiroshi Sakurai: Identification of a Novel Class of Target Genes and a Novel Type of Binding Sequence of Heat Shock Transcription Factor in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 11911-11919. First Published on January 11, 2005; doi:10.1074/jbc.M411256200 [Abstract] [Full Text] [PDF]

Wei-Jong Shia, Shigehiro Osada, Laurence Florens, Selene K. Swanson, Michael P. Washburn, and Jerry L. Workman: Characterization of the Yeast Trimeric-SAS Acetyltransferase Complex
J. Biol. Chem. 2005 280: 11987-11994. First Published on January 18, 2005; doi:10.1074/jbc.M500276200 [Abstract] [Full Text] [PDF]

Lin Ma, Nikolas G. Tsatsos, and Howard C. Towle: Direct Role of ChREBP·Mlx in Regulating Hepatic Glucose-responsive Genes
J. Biol. Chem. 2005 280: 12019-12027. First Published on January 20, 2005; doi:10.1074/jbc.M413063200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Kelly Salinas, Sara Wierzbicki, Li Zhou, and Mark E. Schmitt: Characterization and Purification of Saccharomyces cerevisiae RNase MRP Reveals a New Unique Protein Component
J. Biol. Chem. 2005 280: 11352-11360. First Published on January 6, 2005; doi:10.1074/jbc.M409568200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Rory E. Morty, Roger Pellé, István Vadász, Graciela L. Uzcanga, Werner Seeger, and José Bubis: Oligopeptidase B from Trypanosoma evansi: A PARASITE PEPTIDASE THAT INACTIVATES ATRIAL NATRIURETIC FACTOR IN THE BLOODSTREAM OF INFECTED HOSTS
J. Biol. Chem. 2005 280: 10925-10937. First Published on January 11, 2005; doi:10.1074/jbc.M410066200 [Abstract] [Full Text] [PDF]

YiJiang Shi, Anushree Sharma, Hong Wu, Alan Lichtenstein, and Joseph Gera: Cyclin D1 and c-myc Internal Ribosome Entry Site (IRES)-dependent Translation Is Regulated by AKT Activity and Enhanced by Rapamycin through a p38 MAPK- and ERK-dependent Pathway
J. Biol. Chem. 2005 280: 10964-10973. First Published on January 4, 2005; doi:10.1074/jbc.M407874200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Naima Ismaili, Raymond Blind, and Michael J. Garabedian: Stabilization of the Unliganded Glucocorticoid Receptor by TSG101
J. Biol. Chem. 2005 280: 11120-11126. First Published on January 18, 2005; doi:10.1074/jbc.M500059200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Luana Fioriti, Sara Dossena, Leanne R. Stewart, Richard S. Stewart, David A. Harris, Gianluigi Forloni, and Roberto Chiesa: Cytosolic Prion Protein (PrP) Is Not Toxic in N2a Cells and Primary Neurons Expressing Pathogenic PrP Mutations
J. Biol. Chem. 2005 280: 11320-11328. First Published on January 4, 2005; doi:10.1074/jbc.M412441200 [Abstract] [Full Text] [PDF]

Mehmet Berkmen, Dana Boyd, and Jon Beckwith: The Nonconsecutive Disulfide Bond of Escherichia coli Phytase (AppA) Renders It Dependent on the Protein-disulfide Isomerase, DsbC
J. Biol. Chem. 2005 280: 11387-11394. First Published on January 10, 2005; doi:10.1074/jbc.M411774200 [Abstract] [Full Text] [PDF]

Nihar Ranjan Jana, Priyanka Dikshit, Anand Goswami, Svetlana Kotliarova, Shigeo Murata, Keiji Tanaka, and Nobuyuki Nukina: Co-chaperone CHIP Associates with Expanded Polyglutamine Protein and Promotes Their Degradation by Proteasomes
J. Biol. Chem. 2005 280: 11635-11640. First Published on January 21, 2005; doi:10.1074/jbc.M412042200 [Abstract] [Full Text] [PDF]

Joungil Choi, Howard D. Rees, Susan T. Weintraub, Allan I. Levey, Lih-Shen Chin, and Lian Li: Oxidative Modifications and Aggregation of Cu,Zn-Superoxide Dismutase Associated with Alzheimer and Parkinson Diseases
J. Biol. Chem. 2005 280: 11648-11655. First Published on January 19, 2005; doi:10.1074/jbc.M414327200 [Abstract] [Full Text] [PDF]

Niki Chondrogianni, Christos Tzavelas, Alexander J. Pemberton, Ioannis P. Nezis, A. Jennifer Rivett, and Efstathios S. Gonos: Overexpression of Proteasome ${beta}$ ₅ Assembled Subunit Increases the Amount of Proteasome and Confers Ameliorated Response to Oxidative Stress and Higher Survival Rates
J. Biol. Chem. 2005 280: 11840-11850. First Published on January 20, 2005; doi:10.1074/jbc.M413007200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yanping Li, David M. Keller, John D. Scott, and Hua Lu: CK2 Phosphorylates SSRP1 and Inhibits Its DNA-binding Activity
J. Biol. Chem. 2005 280: 11869-11875. First Published on January 18, 2005; doi:10.1074/jbc.M413944200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Chin-Rang Yang, Bruce E. Shapiro, She-pin Hung, Eric D. Mjolsness, and G. Wesley Hatfield: A Mathematical Model for the Branched Chain Amino Acid Biosynthetic Pathways of Escherichia coli K12
J. Biol. Chem. 2005 280: 11224-11232. First Published on January 18, 2005; doi:10.1074/jbc.M411471200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ines Thiele, Nathan D. Price, Thuy D. Vo, and Bernhard Ø. Palsson: Candidate Metabolic Network States in Human Mitochondria: IMPACT OF DIABETES, ISCHEMIA, AND DIET
J. Biol. Chem. 2005 280: 11683-11695. First Published on November 30, 2004; doi:10.1074/jbc.M409072200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Theodore E. Carver, Brian Bordeau, Maxwell D. Cummings, Eugene C. Petrella, Michael J. Pucci, Laura E. Zawadzke, Brian A. Dougherty, Jeffrey A. Tredup, James W. Bryson, Joseph Yanchunas, Jr., Michael L. Doyle, Mark R. Witmer, Marina I. Nelen, Renee L. DesJarlais, Edward P. Jaeger, Heather Devine, Eric D. Asel, Barry A. Springer, Roger Bone, F. Raymond Salemme, and Matthew J. Todd: Decrypting the Biochemical Function of an Essential Gene from Streptococcus pneumoniae Using ThermoFluor® Technology
J. Biol. Chem. 2005 280: 11704-11712. First Published on January 5, 2005; doi:10.1074/jbc.M413278200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Rajendrakumar Singh, Inamul Haque, and Faizan Ahmad: Counteracting Osmolyte Trimethylamine N-Oxide Destabilizes Proteins at pH below Its pK_a: MEASUREMENTS OF THERMODYNAMIC PARAMETERS OF PROTEINS IN THE PRESENCE AND ABSENCE OF TRIMETHYLAMINE N-OXIDE
J. Biol. Chem. 2005 280: 11035-11042. First Published on January 14, 2005; doi:10.1074/jbc.M410716200 [Abstract] [Full Text] [PDF]

Pia H. Jensen, Dietmar Weilguny, Finn Matthiesen, Kirsten A. McGuire, Lei Shi, and Peter Højrup: Characterization of the Oligomer Structure of Recombinant Human Mannan-binding Lectin
J. Biol. Chem. 2005 280: 11043-11051. First Published on January 14, 2005; doi:10.1074/jbc.M412472200 [Abstract] [Full Text] [PDF]

Robert M. Breece, Alison Costello, Brian Bennett, Tara K. Sigdel, Megan L. Matthews, David L. Tierney, and Michael W. Crowder: A Five-coordinate Metal Center in Co(II)-substituted VanX
J. Biol. Chem. 2005 280: 11074-11081. First Published on January 17, 2005; doi:10.1074/jbc.M412582200 [Abstract] [Full Text] [PDF]

Matthias Kolberg, Derek T. Logan, Günther Bleifuss, Stephan Pötsch, Britt-Marie Sjöberg, Astrid Gräslund, Wolfgang Lubitz, Günter Lassmann, and Friedhelm Lendzian: A New Tyrosyl Radical on Phe²⁰⁸ as Ligand to the Diiron Center in Escherichia coli Ribonucleotide Reductase, Mutant R2-Y122H: COMBINED X-RAY DIFFRACTION AND EPR/ENDOR STUDIES
J. Biol. Chem. 2005 280: 11233-11246. First Published on January 5, 2005; doi:10.1074/jbc.M414634200 [Abstract] [Full Text] [PDF]

Cécile Féraudet, Nathalie Morel, Stéphanie Simon, Hervé Volland, Yveline Frobert, Christophe Créminon, Didier Vilette, Sylvain Lehmann, and Jacques Grassi: Screening of 145 Anti-PrP Monoclonal Antibodies for Their Capacity to Inhibit PrPSc Replication in Infected Cells
J. Biol. Chem. 2005 280: 11247-11258. First Published on December 23, 2004; doi:10.1074/jbc.M407006200 [Abstract] [Full Text] [PDF]

Shuwen Liu, Hong Lu, Jinkui Niu, Yujia Xu, Shuguang Wu, and Shibo Jiang: Different from the HIV Fusion Inhibitor C34, the Anti-HIV Drug Fuzeon (T-20) Inhibits HIV-1 Entry by Targeting Multiple Sites in gp41 and gp120
J. Biol. Chem. 2005 280: 11259-11273. First Published on January 7, 2005; doi:10.1074/jbc.M411141200 [Abstract] [Full Text] [PDF]

Hao Zhou, Wei Wang, and Yongzhang Luo: Contributions of Disulfide Bonds in a Nested Pattern to the Structure, Stability, and Biological Functions of Endostatin
J. Biol. Chem. 2005 280: 11303-11312. First Published on January 5, 2005; doi:10.1074/jbc.M412072200 [Abstract] [Full Text] [PDF]

Gustav Vaaje-Kolstad, Douglas R. Houston, Anna H. K. Riemen, Vincent G. H. Eijsink, and Daan M. F. van Aalten: Crystal Structure and Binding Properties of the Serratia marcescens Chitin-binding Protein CBP21
J. Biol. Chem. 2005 280: 11313-11319. First Published on December 8, 2004; doi:10.1074/jbc.M407175200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hiroyuki Takashima, Takuya Yoshida, Tetsuya Ishino, Katsumi Hasuda, Tadayasu Ohkubo, and Yuji Kobayashi: Solution NMR Structure Investigation for Releasing Mechanism of Neocarzinostatin Chromophore from the Holoprotein
J. Biol. Chem. 2005 280: 11340-11346. First Published on January 7, 2005; doi:10.1074/jbc.M411579200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jung-In Kim, Chang Jun Lee, Mi Sun Jin, Cherl-Ho Lee, Sang-Gi Paik, Hayyoung Lee, and Jie-Oh Lee: Crystal Structure of CD14 and Its Implications for Lipopolysaccharide Signaling
J. Biol. Chem. 2005 280: 11347-11351. First Published on January 10, 2005; doi:10.1074/jbc.M414607200 [Abstract] [Full Text] [PDF] [Summary]

Amarnath Chatterjee, P. Mridula, Ram Kumar Mishra, Rohit Mittal, and Ramakrishna V. Hosur: Folding Regulates Autoprocessing of HIV-1 Protease Precursor
J. Biol. Chem. 2005 280: 11369-11378. First Published on January 4, 2005; doi:10.1074/jbc.M412603200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Stan J. J. Brouns, Hao Wu, Jasper Akerboom, Andrew P. Turnbull, Willem M. de Vos, and John van der Oost: Engineering a Selectable Marker for Hyperthermophiles
J. Biol. Chem. 2005 280: 11422-11431. First Published on January 7, 2005; doi:10.1074/jbc.M413623200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bonney Wilkinson, Ruoyu Xiao, and Hiram F. Gilbert: A Structural Disulfide of Yeast Protein-disulfide Isomerase Destabilizes the Active Site Disulfide of the N-terminal Thioredoxin Domain
J. Biol. Chem. 2005 280: 11483-11487. First Published on January 13, 2005; doi:10.1074/jbc.M414203200 [Abstract] [Full Text] [PDF]

Matthew James Bottomley, Gunter Stier, Danilo Pennacchini, Gaelle Legube, Bernd Simon, Asifa Akhtar, Michael Sattler, and Giovanna Musco: NMR Structure of the First PHD Finger of Autoimmune Regulator Protein (AIRE1): INSIGHTS INTO AUTOIMMUNE POLYENDOCRINOPATHY-CANDIDIASIS-ECTODERMAL DYSTROPHY (APECED) DISEASE
J. Biol. Chem. 2005 280: 11505-11512. First Published on January 13, 2005; doi:10.1074/jbc.M413959200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bin Zhao, F. Peter Guengerich, Aouatef Bellamine, David C. Lamb, Miho Izumikawa, Li Lei, Larissa M. Podust, Munirathinam Sundaramoorthy, John A. Kalaitzis, L. Manmohan Reddy, Steven L. Kelly, Bradley S. Moore, Donald Stec, Markus Voehler, John R. Falck, Tsutomu Shimada, and Michael R. Waterman: Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2
J. Biol. Chem. 2005 280: 11599-11607. First Published on January 19, 2005; doi:10.1074/jbc.M410933200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chun Tang, David C. Williams, Jr., Rodolfo Ghirlando, and G. Marius Clore: Solution Structure of Enzyme IIA^Chitobiose from the N,N'-Diacetylchitobiose Branch of the Escherichia coli Phosphotransferase System
J. Biol. Chem. 2005 280: 11770-11780. First Published on January 14, 2005; doi:10.1074/jbc.M414300200 [Abstract] [Full Text] [PDF]

Kristian W. Sanggaard, Henrik Karring, Zuzana Valnickova, Ida B. Thøgersen, and Jan J. Enghild: The TSG-6 and I ${alpha}$ I Interaction Promotes a Transesterification Cleaving the Protein-Glycosaminoglycan-Protein (PGP) Cross-link
J. Biol. Chem. 2005 280: 11936-11942. First Published on January 14, 2005; doi:10.1074/jbc.M409016200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kathrin Müntener, Anna Willimann, Roman Zwicky, Barbara Svoboda, Lukas Mach, and Antonio Baici: Folding Competence of N-terminally Truncated Forms of Human Procathepsin B
J. Biol. Chem. 2005 280: 11973-11980. First Published on January 18, 2005; doi:10.1074/jbc.M413052200 [Abstract] [Full Text] [PDF]

Miho Kihara, Eri Chatani, Miyo Sakai, Kazuhiro Hasegawa, Hironobu Naiki, and Yuji Goto: Seeding-dependent Maturation of ${beta}$ ₂-Microglobulin Amyloid Fibrils at Neutral pH
J. Biol. Chem. 2005 280: 12012-12018. First Published on January 19, 2005; doi:10.1074/jbc.M411949200 [Abstract] [Full Text] [PDF]

Bei-Wen Ying, Hideki Taguchi, Mayumi Kondo, and Takuya Ueda: Co-translational Involvement of the Chaperonin GroEL in the Folding of Newly Translated Polypeptides
J. Biol. Chem. 2005 280: 12035-12040. First Published on January 21, 2005; doi:10.1074/jbc.M500364200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Katie Ownby, Huimin Xu, and Robert H. White: A Methanocaldococcus jannaschii Archaeal Signature Gene Encodes for a 5-Formaminoimidazole-4-carboxamide-1- ${beta}$ -D-ribofuranosyl 5'-Monophosphate Synthetase: A NEW ENZYME IN PURINE BIOSYNTHESIS
J. Biol. Chem. 2005 280: 10881-10887. First Published on December 28, 2004; doi:10.1074/jbc.M413937200 [Abstract] [Full Text] [PDF]

Jian Cao, Alnawaz Rehemtulla, Maria Pavlaki, Pallavi Kozarekar, and Christian Chiarelli: Furin Directly Cleaves proMMP-2 in the trans-Golgi Network Resulting in a Nonfunctioning Proteinase
J. Biol. Chem. 2005 280: 10974-10980. First Published on January 6, 2005; doi:10.1074/jbc.M412370200 [Abstract] [Full Text] [PDF]

Nathan Cobb, Thomas Conrads, and Russ Hille: Mechanistic Studies of Rhodobacter sphaeroides Me₂SO Reductase
J. Biol. Chem. 2005 280: 11007-11017. First Published on January 12, 2005; doi:10.1074/jbc.M412050200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jack L. Leonard, Gregory Simpson, and Deborah M. Leonard: Characterization of the Protein Dimerization Domain Responsible for Assembly of Functional Selenodeiodinases
J. Biol. Chem. 2005 280: 11093-11100. First Published on January 18, 2005; doi:10.1074/jbc.M500011200 [Abstract] [Full Text] [PDF]

Philipp Kaldis: The N-terminal Peptide of the Kaposi's Sarcoma-associated Herpesvirus (KSHV)-cyclin Determines Substrate Specificity
J. Biol. Chem. 2005 280: 11165-11174. First Published on January 21, 2005; doi:10.1074/jbc.M408887200 [Abstract] [Full Text] [PDF]

Gerwald A. Köhler, Xin Gong, Stefan Bentink, Stephanie Theiss, Gina M. Pagani, Nina Agabian, and Lizbeth Hedstrom: The Functional Basis of Mycophenolic Acid Resistance in Candida albicans IMP Dehydrogenase
J. Biol. Chem. 2005 280: 11295-11302. First Published on January 21, 2005; doi:10.1074/jbc.M409847200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kelly Neelon, Yan Wang, Boguslaw Stec, and Mary F. Roberts: Probing the Mechanism of the Archaeoglobus fulgidus Inositol-1-phosphate Synthase
J. Biol. Chem. 2005 280: 11475-11482. First Published on January 14, 2005; doi:10.1074/jbc.M500469200 [Abstract] [Full Text] [PDF]

Fu-Jung Chang, Scott Lemme, Qian Sun, Roger K. Sunahara, and Annie Beuve: Nitric Oxide-dependent Allosteric Inhibitory Role of a Second Nucleotide Binding Site in Soluble Guanylyl Cyclase
J. Biol. Chem. 2005 280: 11513-11519. First Published on January 12, 2005; doi:10.1074/jbc.M412203200 [Abstract] [Full Text] [PDF] [Supplemental Data]

James R. Birtley, Stephen R. Knox, Agnès M. Jaulent, Peter Brick, Robin J. Leatherbarrow, and Stephen Curry: Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease: NEW INSIGHTS INTO CATALYTIC MECHANISM AND CLEAVAGE SPECIFICITY
J. Biol. Chem. 2005 280: 11520-11527. First Published on January 14, 2005; doi:10.1074/jbc.M413254200 [Abstract] [Full Text] [PDF]

Xiangyuan He, Feng Li, Wan-Pin Chang, and Jordan Tang: GGA Proteins Mediate the Recycling Pathway of Memapsin 2 (BACE)
J. Biol. Chem. 2005 280: 11696-11703. First Published on December 21, 2004; doi:10.1074/jbc.M411296200 [Abstract] [Full Text] [PDF]

Akiko Takahashi-Terada, Masaaki Kotera, Kenta Ohshima, Tsuyoshi Furumoto, Hiroyoshi Matsumura, Yasushi Kai, and Katsura Izui: Maize Phosphoenolpyruvate Carboxylase: MUTATIONS AT THE PUTATIVE BINDING SITE FOR GLUCOSE 6-PHOSPHATE CAUSED DESENSITIZATION AND ABOLISHED RESPONSIVENESS TO REGULATORY PHOSPHORYLATION
J. Biol. Chem. 2005 280: 11798-11806. First Published on January 21, 2005; doi:10.1074/jbc.M408768200 [Abstract] [Full Text] [PDF]

Blythe E. Janowiak and Owen W. Griffith: Glutathione Synthesis in Streptococcus agalactiae: ONE PROTEIN ACCOUNTS FOR ${gamma}$ -GLUTAMYLCYSTEINE SYNTHETASE AND GLUTATHIONE SYNTHETASE ACTIVITIES
J. Biol. Chem. 2005 280: 11829-11839. First Published on January 10, 2005; doi:10.1074/jbc.M414326200 [Abstract] [Full Text] [PDF]

Hui-jun Yu, Jun-qiu Liu, August Böck, Jing Li, Gui-min Luo, and Jia-cong Shen: Engineering Glutathione Transferase to a Novel Glutathione Peroxidase Mimic With High Catalytic Efficiency: INCORPORATION OF SELENOCYSTEINE INTO A GLUTATHIONE-BINDING SCAFFOLD USING AN AUXOTROPHIC EXPRESSION SYSTEM
J. Biol. Chem. 2005 280: 11930-11935. First Published on January 13, 2005; doi:10.1074/jbc.M408574200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Qingli Shi, Huan-Lian Chen, Hui Xu, and Gary E. Gibson: Reduction in the E2k Subunit of the ${alpha}$ -Ketoglutarate Dehydrogenase Complex Has Effects Independent of Complex Activity
J. Biol. Chem. 2005 280: 10888-10896. First Published on January 12, 2005; doi:10.1074/jbc.M409064200 [Abstract] [Full Text] [PDF]

Jamie S. Harmon, Roland Stein, and R. Paul Robertson: Oxidative Stress-mediated, Post-translational Loss of MafA Protein as a Contributing Mechanism to Loss of Insulin Gene Expression in Glucotoxic Beta Cells
J. Biol. Chem. 2005 280: 11107-11113. First Published on January 20, 2005; doi:10.1074/jbc.M410345200 [Abstract] [Full Text] [PDF]

Abhijit Ghosh, Yuk Yin Cheung, Brian C. Mansfield, and Janice Yang Chou: Brain Contains a Functional Glucose-6-Phosphatase Complex Capable of Endogenous Glucose Production
J. Biol. Chem. 2005 280: 11114-11119. First Published on January 20, 2005; doi:10.1074/jbc.M410894200 [Abstract] [Full Text] [PDF]

Frédéric Comayras, Colette Jungas, and Jérôme Lavergne: Functional Consequences of the Organization of the Photosynthetic Apparatus in Rhodobacter sphaeroides: I. QUINONE DOMAINS AND EXCITATION TRANSFER IN CHROMATOPHORES AND REACTION CENTER·ANTENNA COMPLEXES
J. Biol. Chem. 2005 280: 11203-11213. First Published on January 4, 2005; doi:10.1074/jbc.M412088200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Frédéric Comayras, Colette Jungas, and Jérôme Lavergne: Functional Consequences of the Organization of the Photosynthetic Apparatus in Rhodobacter sphaeroides: II. A STUDY OF PufX^– MEMBRANES
J. Biol. Chem. 2005 280: 11214-11223. First Published on January 4, 2005; doi:10.1074/jbc.M412089200 [Abstract] [Full Text] [PDF]

Michael L. Ginger, E. Solange Ngazoa, Claudio A. Pereira, Timothy J. Pullen, Mostafa Kabiri, Katja Becker, Keith Gull, and Dietmar Steverding: Intracellular Positioning of Isoforms Explains an Unusually Large Adenylate Kinase Gene Family in the Parasite Trypanosoma brucei
J. Biol. Chem. 2005 280: 11781-11789. First Published on January 18, 2005; doi:10.1074/jbc.M413821200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nadia Lamour, Loïc Rivière, Virginie Coustou, Graham H. Coombs, Michael P. Barrett, and Frédéric Bringaud: Proline Metabolism in Procyclic Trypanosoma brucei Is Down-regulated in the Presence of Glucose
J. Biol. Chem. 2005 280: 11902-11910. First Published on January 21, 2005; doi:10.1074/jbc.M414274200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Motoki Terada, Kay-Hooi Khoo, Risa Inoue, Chun-I Chen, Kanako Yamada, Hiromi Sakaguchi, Naoko Kadowaki, Bruce Yong Ma, Shogo Oka, Toshisuke Kawasaki, and Nobuko Kawasaki: Characterization of Oligosaccharide Ligands Expressed on SW1116 Cells Recognized by Mannan-binding Protein: A HIGHLY FUCOSYLATED POLYLACTOSAMINE TYPE N-GLYCAN
J. Biol. Chem. 2005 280: 10897-10913. First Published on January 5, 2005; doi:10.1074/jbc.M413092200 [Abstract] [Full Text] [PDF]

Yasumasa Kato, Charles A. Lambert, Alain C. Colige, Pierre Mineur, Agnés Noël, Francis Frankenne, Jean-Michel Foidart, Masaya Baba, Ryu-Ichiro Hata, Kaoru Miyazaki, and Mamoru Tsukuda: Acidic Extracellular pH Induces Matrix Metalloproteinase-9 Expression in Mouse Metastatic Melanoma Cells through the Phospholipase D-Mitogen-activated Protein Kinase Signaling
J. Biol. Chem. 2005 280: 10938-10944. First Published on January 18, 2005; doi:10.1074/jbc.M411313200 [Abstract] [Full Text] [PDF]

Anke Schnepp, Patricia Komp Lindgren, Hanni Hülsmann, Stephan Kröger, Mats Paulsson, and Ursula Hartmann: Mouse Testican-2: EXPRESSION, GLYCOSYLATION, AND EFFECTS ON NEURITE OUTGROWTH
J. Biol. Chem. 2005 280: 11274-11280. First Published on January 17, 2005; doi:10.1074/jbc.M414276200 [Abstract] [Full Text] [PDF]

Yi Luo and Robert S. Haltiwanger: O-Fucosylation of Notch Occurs in the Endoplasmic Reticulum
J. Biol. Chem. 2005 280: 11289-11294. First Published on January 14, 2005; doi:10.1074/jbc.M414574200 [Abstract] [Full Text] [PDF]

Kerstin Tiedemann, Takako Sasaki, Erika Gustafsson, Walter Göhring, Boris Bätge, Holger Notbohm, Rupert Timpl, Thilo Wedel, Ursula Schlötzer-Schrehardt, and Dieter P. Reinhardt: Microfibrils at Basement Membrane Zones Interact with Perlecan via Fibrillin-1
J. Biol. Chem. 2005 280: 11404-11412. First Published on January 17, 2005; doi:10.1074/jbc.M409882200 [Abstract] [Full Text] [PDF]

Edward R. Bastow, Katherine J. Lamb, Jo C. Lewthwaite, Anne C. Osborne, Emma Kavanagh, Caroline P. D. Wheeler-Jones, and Andrew A. Pitsillides: Selective Activation of the MEK-ERK Pathway Is Regulated by Mechanical Stimuli in Forming Joints and Promotes Pericellular Matrix Formation
J. Biol. Chem. 2005 280: 11749-11758. First Published on January 12, 2005; doi:10.1074/jbc.M414495200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Ruth E. Haites, Yasu S. Morita, Malcolm J. McConville, and Helen Billman-Jacobe: Function of Phosphatidylinositol in Mycobacteria
J. Biol. Chem. 2005 280: 10981-10987. First Published on January 5, 2005; doi:10.1074/jbc.M413443200 [Abstract] [Full Text] [PDF]

Kazuhito Tsuboi, Yong-Xin Sun, Yasuo Okamoto, Nobukazu Araki, Takeharu Tonai, and Natsuo Ueda: Molecular Characterization of N-Acylethanolamine-hydrolyzing Acid Amidase, a Novel Member of the Choloylglycine Hydrolase Family with Structural and Functional Similarity to Acid Ceramidase
J. Biol. Chem. 2005 280: 11082-11092. First Published on January 17, 2005; doi:10.1074/jbc.M413473200 [Abstract] [Full Text] [PDF]

Wenxin Yu, Jian-Sheng Gong, Mihee Ko, William S. Garver, Katsuhiko Yanagisawa, and Makoto Michikawa: Altered Cholesterol Metabolism in Niemann-Pick Type C1 Mouse Brains Affects Mitochondrial Function
J. Biol. Chem. 2005 280: 11731-11739. First Published on January 11, 2005; doi:10.1074/jbc.M412898200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yan Wang, Adam B. Castoreno, Walter Stockinger, and Axel Nohturfft: Modulation of Endosomal Cholesteryl Ester Metabolism by Membrane Cholesterol
J. Biol. Chem. 2005 280: 11876-11886. First Published on January 18, 2005; doi:10.1074/jbc.M414676200 [Abstract] [Full Text] [PDF]

Angela M. Hall, Brian M. Wiczer, Thomas Herrmann, Wolfgang Stremmel, and David A. Bernlohr: Enzymatic Properties of Purified Murine Fatty Acid Transport Protein 4 and Analysis of Acyl-CoA Synthetase Activities in Tissues from FATP4 Null Mice
J. Biol. Chem. 2005 280: 11948-11954. First Published on January 14, 2005; doi:10.1074/jbc.M412629200 [Abstract] [Full Text] [PDF]

Edgar M. Harvat, Yong-Mei Zhang, Can V. Tran, Zhongge Zhang, Matthew W. Frank, Charles O. Rock, and Milton H. Saier, Jr.: Lysophospholipid Flipping across the Escherichia coli Inner Membrane Catalyzed by a Transporter (LplT) Belonging to the Major Facilitator Superfamily
J. Biol. Chem. 2005 280: 12028-12034. First Published on January 20, 2005; doi:10.1074/jbc.M414368200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Frank Visser, Stephen A. Baldwin, R. Elwyn Isaac, James D. Young, and Carol E. Cass: Identification and Mutational Analysis of Amino Acid Residues Involved in Dipyridamole Interactions with Human and Caenorhabditis elegans Equilibrative Nucleoside Transporters
J. Biol. Chem. 2005 280: 11025-11034. First Published on January 13, 2005; doi:10.1074/jbc.M410348200 [Abstract] [Full Text] [PDF]

Jaime J. Smith, Sujith Alphy, Anna L. Seibert, and Kenneth M. Blumenthal: Differential Phospholipid Binding by Site 3 and Site 4 Toxins: IMPLICATIONS FOR STRUCTURAL VARIABILITY BETWEEN VOLTAGE-SENSITIVE SODIUM CHANNEL DOMAINS
J. Biol. Chem. 2005 280: 11127-11133. First Published on January 4, 2005; doi:10.1074/jbc.M412552200 [Abstract] [Full Text] [PDF]

Zdzislaw Salamon, Savitha Devanathan, Isabel D. Alves, and Gordon Tollin: Plasmon-waveguide Resonance Studies of Lateral Segregation of Lipids and Proteins into Microdomains (Rafts) in Solid-supported Bilayers
J. Biol. Chem. 2005 280: 11175-11184. First Published on January 24, 2005; doi:10.1074/jbc.M411197200 [Abstract] [Full Text] [PDF]

Herman G. P. Swarts, Jan B. Koenderink, Peter H. G. M. Willems, Elmar Krieger, and Jan Joep H. H. M. De Pont: Asn⁷⁹² Participates in the Hydrogen Bond Network Around the K⁺-binding Pocket of Gastric H,K-ATPase
J. Biol. Chem. 2005 280: 11488-11494. First Published on January 11, 2005; doi:10.1074/jbc.M412321200 [Abstract] [Full Text] [PDF]

Adam D. Humphries, Illo C. Streimann, Diana Stojanovski, Amelia J. Johnston, Masato Yano, Nicholas J. Hoogenraad, and Michael T. Ryan: Dissection of the Mitochondrial Import and Assembly Pathway for Human Tom40
J. Biol. Chem. 2005 280: 11535-11543. First Published on January 10, 2005; doi:10.1074/jbc.M413816200 [Abstract] [Full Text] [PDF]

Minghui Xiang, Deepti Mohamalawari, and Rajini Rao: A Novel Isoform of the Secretory Pathway Ca²⁺,Mn²⁺-ATPase, hSPCA2, Has Unusual Properties and Is Expressed in the Brain
J. Biol. Chem. 2005 280: 11608-11614. First Published on January 27, 2005; doi:10.1074/jbc.M413116200 [Abstract] [Full Text] [PDF]

Xiao-Li Wang, Dan Ye, Timothy E. Peterson, Sheng Cao, Vijay H. Shah, Zvonimir S. Katusic, Gary C. Sieck, and Hon-Chi Lee: Caveolae Targeting and Regulation of Large Conductance Ca²⁺-activated K⁺ Channels in Vascular Endothelial Cells
J. Biol. Chem. 2005 280: 11656-11664. First Published on January 23, 2005; doi:10.1074/jbc.M410987200 [Abstract] [Full Text] [PDF]

Chihiro Hisatsune, Kyoko Nakamura, Yukiko Kuroda, Takeshi Nakamura, and Katsuhiko Mikoshiba: Amplification of Ca²⁺ Signaling by Diacylglycerol-mediated Inositol 1,4,5-Trisphosphate Production
J. Biol. Chem. 2005 280: 11723-11730. First Published on January 6, 2005; doi:10.1074/jbc.M409535200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Seema Saksena, Ravinder K. Gill, Sangeeta Tyagi, Waddah A. Alrefai, Zaheer Sarwar, Krishnamurthy Ramaswamy, and Pradeep K. Dudeja: Involvement of c-Src and Protein Kinase C ${delta}$ in the Inhibition of Cl^-/OH^- Exchange Activity in Caco-2 Cells by Serotonin
J. Biol. Chem. 2005 280: 11859-11868. First Published on January 6, 2005; doi:10.1074/jbc.M411553200 [Abstract] [Full Text] [PDF]

Susanna Bodoy, Lorena Martín, Antonio Zorzano, Manuel Palacín, Raúl Estévez, and Joan Bertran: Identification of LAT4, a Novel Amino Acid Transporter with System L Activity
J. Biol. Chem. 2005 280: 12002-12011. First Published on January 19, 2005; doi:10.1074/jbc.M408638200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

L'Aurelle A. Johnson, Bipasha Guptaroy, David Lund, Susanna Shamban, and Margaret E. Gnegy: Regulation of Amphetamine-stimulated Dopamine Efflux by Protein Kinase C ${beta}$
J. Biol. Chem. 2005 280: 10914-10919. First Published on January 12, 2005; doi:10.1074/jbc.M413887200 [Abstract] [Full Text] [PDF]

Mekky M. Abouzied, Heba Mahmoud El-tahir, Lars Prenner, Hanns Häberlein, Volkmar Gieselmann, and Sebastian Franken: Hepatoma-derived Growth Factor: SIGNIFICANCE OF AMINO ACID RESIDUES 81–100 IN CELL SURFACE INTERACTION AND PROLIFERATIVE ACTIVITY
J. Biol. Chem. 2005 280: 10945-10954. First Published on January 17, 2005; doi:10.1074/jbc.M414652200 [Abstract] [Full Text] [PDF]

Hua Gao, Shunqian Jin, Yongmei Song, Ming Fu, Minrong Wang, Zhihua Liu, Min Wu, and Qimin Zhan: B23 Regulates GADD45a Nuclear Translocation and Contributes to GADD45a-induced Cell Cycle G₂-M Arrest
J. Biol. Chem. 2005 280: 10988-10996. First Published on January 10, 2005; doi:10.1074/jbc.M412720200 [Abstract] [Full Text] [PDF]

Li-Ping He, Thamara Hewavitharana, Jonathan Soboloff, Maria A. Spassova, and Donald L. Gill: A Functional Link between Store-operated and TRPC Channels Revealed by the 3,5-Bis(trifluoromethyl)pyrazole Derivative, BTP2
J. Biol. Chem. 2005 280: 10997-11006. First Published on January 12, 2005; doi:10.1074/jbc.M411797200 [Abstract] [Full Text] [PDF]

Stephen Marshall, Owen Nadeau, and Kazumitsu Yamasaki: Glucosamine-induced Activation of Glycogen Biosynthesis in Isolated Adipocytes: EVIDENCE FOR A RAPID ALLOSTERIC CONTROL MECHANISM WITHIN THE HEXOSAMINE BIOSYNTHESIS PATHWAY
J. Biol. Chem. 2005 280: 11018-11024. First Published on January 12, 2005; doi:10.1074/jbc.M413499200 [Abstract] [Full Text] [PDF]

Christina S. Pao and Jeffrey L. Benovic: Structure/Function Analysis of ${alpha}$ _2A-Adrenergic Receptor Interaction with G Protein-coupledReceptor Kinase 2
J. Biol. Chem. 2005 280: 11052-11058. First Published on January 14, 2005; doi:10.1074/jbc.M412996200 [Abstract] [Full Text] [PDF]

Merideth C. Kamradt, Meiling Lu, Michael E. Werner, Toni Kwan, Feng Chen, Anne Strohecker, Shayna Oshita, John C. Wilkinson, Chunjiang Yu, Patsy G. Oliver, Colin S. Duckett, Donald J. Buchsbaum, Albert F. LoBuglio, V. Craig Jordan, and Vincent L. Cryns: The Small Heat Shock Protein ${alpha}$ B-crystallin Is a Novel Inhibitor of TRAIL-induced Apoptosis That Suppresses the Activation of Caspase-3
J. Biol. Chem. 2005 280: 11059-11066. First Published on January 14, 2005; doi:10.1074/jbc.M413382200 [Abstract] [Full Text] [PDF]

Stefanie S. Schalm, Andrew R. Tee, and John Blenis: Characterization of a Conserved C-terminal Motif (RSPRR) in Ribosomal Protein S6 Kinase 1 Required for Its Mammalian Target of Rapamycin-dependent Regulation
J. Biol. Chem. 2005 280: 11101-11106. First Published on January 19, 2005; doi:10.1074/jbc.M413995200 [Abstract] [Full Text] [PDF]

Susanne Lutz, Andrea Freichel-Blomquist, Yang Yang, Ulrich Rümenapp, Karl H. Jakobs, Martina Schmidt, and Thomas Wieland: The Guanine Nucleotide Exchange Factor p63RhoGEF, a Specific Link between G_q/11-coupled Receptor Signaling and RhoA
J. Biol. Chem. 2005 280: 11134-11139. First Published on January 4, 2005; doi:10.1074/jbc.M411322200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mingliang Zhang and Gerda E. Breitwieser: High Affinity Interaction with Filamin A Protects against Calcium-sensing Receptor Degradation
J. Biol. Chem. 2005 280: 11140-11146. First Published on January 18, 2005; doi:10.1074/jbc.M412242200 [Abstract] [Full Text] [PDF]

Deepak Raina, Pramod Pandey, Rehan Ahmad, Ajit Bharti, Jian Ren, Surender Kharbanda, Ralph Weichselbaum, and Donald Kufe: c-Abl Tyrosine Kinase Regulates Caspase-9 Autocleavage in the Apoptotic Response to DNA Damage
J. Biol. Chem. 2005 280: 11147-11151. First Published on January 18, 2005; doi:10.1074/jbc.M413787200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ping-Yee Law, Laurie J. Erickson-Herbrandson, Qin Q. Zha, Jon Solberg, Ji Chu, Aili Sarre, and Horace H. Loh: Heterodimerization of µ- and ${delta}$ -Opioid Receptors Occurs at the Cell Surface Only and Requires Receptor-G Protein Interactions
J. Biol. Chem. 2005 280: 11152-11164. First Published on January 18, 2005; doi:10.1074/jbc.M500171200 [Abstract] [Full Text] [PDF]

Bauer E. Sumpio, Sangseob Yun, Alfredo C. Cordova, Masae Haga, Jin Zhang, Yongbok Koh, and Joseph A. Madri: MAPKs (ERK $1/2$ , p38) and AKT Can Be Phosphorylated by Shear Stress Independently of Platelet Endothelial Cell Adhesion Molecule-1 (CD31) in Vascular Endothelial Cells
J. Biol. Chem. 2005 280: 11185-11191. First Published on January 24, 2005; doi:10.1074/jbc.M414631200 [Abstract] [Full Text] [PDF]

Colin A. Syme, Peter A. Friedman, and Alessandro Bisello: Parathyroid Hormone Receptor Trafficking Contributes to the Activation of Extracellular Signal-regulated Kinases but Is Not Required for Regulation of cAMP Signaling
J. Biol. Chem. 2005 280: 11281-11288. First Published on December 17, 2004; doi:10.1074/jbc.M413393200 [Abstract] [Full Text] [PDF]

Antonio Mazzocca, Silvia Cappadona Sciammetta, Vinicio Carloni, Lorenzo Cosmi, Francesco Annunziato, Takashi Harada, Sergio Abrignani, and Massimo Pinzani: Binding of Hepatitis C Virus Envelope Protein E2 to CD81 Up-regulates Matrix Metalloproteinase-2 in Human Hepatic Stellate Cells
J. Biol. Chem. 2005 280: 11329-11339. First Published on December 16, 2004; doi:10.1074/jbc.M410161200 [Abstract] [Full Text] [PDF]

Gurjit Sidhu, Wei Li, Nicholas Laryngakis, Ellen Bishai, Tamas Balla, and Frederick Southwick: Phosphoinositide 3-Kinase Is Required for Intracellular Listeria monocytogenes Actin-based Motility and Filopod Formation
J. Biol. Chem. 2005 280: 11379-11386. First Published on January 10, 2005; doi:10.1074/jbc.M414533200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Yasuhiro Kobayashi, Toshihide Mizoguchi, Ikuko Take, Saburo Kurihara, Nobuyuki Udagawa, and Naoyuki Takahashi: Prostaglandin E₂ Enhances Osteoclastic Differentiation of Precursor Cells through Protein Kinase A-dependent Phosphorylation of TAK1
J. Biol. Chem. 2005 280: 11395-11403. First Published on January 12, 2005; doi:10.1074/jbc.M411189200 [Abstract] [Full Text] [PDF] [Supplemental Data]

J. Dedrick Jordan, John Cijiang He, Narat J. Eungdamrong, Ivone Gomes, Wasif Ali, Tracy Nguyen, Trever G. Bivona, Mark R. Philips, Lakshmi A. Devi, and Ravi Iyengar: Cannabinoid Receptor-induced Neurite Outgrowth Is Mediated by Rap1 Activation through G ${alpha}$ _o/i-triggered Proteasomal Degradation of Rap1GAPII
J. Biol. Chem. 2005 280: 11413-11421. First Published on January 18, 2005; doi:10.1074/jbc.M411521200 [Abstract] [Full Text] [PDF]

Bruns A. Watts, III, Thampi George, and David W. Good: The Basolateral NHE1 Na⁺/H⁺ Exchanger Regulates Transepithelial HCO ^-₃ Absorption through Actin Cytoskeleton Remodeling in Renal Thick Ascending Limb
J. Biol. Chem. 2005 280: 11439-11447. First Published on January 11, 2005; doi:10.1074/jbc.M410719200 [Abstract] [Full Text] [PDF]

Lina Vardouli, Aristidis Moustakas, and Christos Stournaras: LIM-kinase 2 and Cofilin Phosphorylation Mediate Actin Cytoskeleton Reorganization Induced by Transforming Growth Factor- ${beta}$
J. Biol. Chem. 2005 280: 11448-11457. First Published on January 11, 2005; doi:10.1074/jbc.M402651200 [Abstract] [Full Text] [PDF]

Rui Wang, Pratima Cherukuri, and Jianyuan Luo: Activation of Stat3 Sequence-specific DNA Binding and Transcription by p300/CREB-binding Protein-mediated Acetylation
J. Biol. Chem. 2005 280: 11528-11534. First Published on January 13, 2005; doi:10.1074/jbc.M413930200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Stephen J. Perry, Sachiko Junger, Trudy A. Kohout, Sam R. J. Hoare, R. Scott Struthers, Dimitri E. Grigoriadis, and Richard A. Maki: Distinct Conformations of the Corticotropin Releasing Factor Type 1 Receptor Adopted following Agonist and Antagonist Binding Are Differentially Regulated
J. Biol. Chem. 2005 280: 11560-11568. First Published on January 14, 2005; doi:10.1074/jbc.M412914200 [Abstract] [Full Text] [PDF]

Adam I. Marcus, Ulf Peters, Shala L. Thomas, Sarah Garrett, Amelia Zelnak, Tarun M. Kapoor, and Paraskevi Giannakakou: Mitotic Kinesin Inhibitors Induce Mitotic Arrest and Cell Death in Taxol-resistant and -sensitive Cancer Cells
J. Biol. Chem. 2005 280: 11569-11577. First Published on January 13, 2005; doi:10.1074/jbc.M413471200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hongtu Liu, David W. Chang, and Xiaolu Yang: Interdimer Processing and Linearity of Procaspase-3 Activation: A UNIFYING MECHANISM FOR THE ACTIVATION OF INITIATOR AND EFFECTOR CASPASES
J. Biol. Chem. 2005 280: 11578-11582. First Published on January 21, 2005; doi:10.1074/jbc.M414385200 [Abstract] [Full Text] [PDF]

Elizabeth A. Kasbohm, Rishu Guo, Charles W. Yowell, Gargi Bagchi, Patrick Kelly, Puneeta Arora, Patrick J. Casey, and Yehia Daaka: Androgen Receptor Activation by G_s Signaling in Prostate Cancer Cells
J. Biol. Chem. 2005 280: 11583-11589. First Published on January 14, 2005; doi:10.1074/jbc.M414423200 [Abstract] [Full Text] [PDF]

Chad N. Hancock, Surabhi Dangi, and Paul Shapiro: Protein Phosphatase 2A Activity Associated with Golgi Membranes during the G₂/M Phase May Regulate Phosphorylation of ERK2
J. Biol. Chem. 2005 280: 11590-11598. First Published on January 14, 2005; doi:10.1074/jbc.M408273200 [Abstract] [Full Text] [PDF]

Rodrigo A. Quintanilla, Francisco J. Muñoz, Maria J. Metcalfe, Maureen Hitschfeld, Gonzalo Olivares, Juan A. Godoy, and Nibaldo C. Inestrosa: Trolox and 17 ${beta}$ -Estradiol Protect against Amyloid ${beta}$ -Peptide Neurotoxicity by a Mechanism That Involves Modulation of the Wnt Signaling Pathway
J. Biol. Chem. 2005 280: 11615-11625. First Published on January 19, 2005; doi:10.1074/jbc.M411936200 [Abstract] [Full Text] [PDF]

Consuelo Gajate and Faustino Mollinedo: Cytoskeleton-mediated Death Receptor and Ligand Concentration in Lipid Rafts Forms Apoptosis-promoting Clusters in Cancer Chemotherapy
J. Biol. Chem. 2005 280: 11641-11647. First Published on January 19, 2005; doi:10.1074/jbc.M411781200 [Abstract] [Full Text] [PDF]

George G. Rodney, Gerald M. Wilson, and Martin F. Schneider: A Calmodulin Binding Domain of RyR Increases Activation of Spontaneous Ca²⁺ Sparks in Frog Skeletal Muscle
J. Biol. Chem. 2005 280: 11713-11722. First Published on January 6, 2005; doi:10.1074/jbc.M408189200 [Abstract] [Full Text] [PDF]

S. D. Yogesha, Shruti M. Khapli, and Mohan R. Wani: Interleukin-3 and Granulocyte-Macrophage Colony-stimulating Factor Inhibits Tumor Necrosis Factor (TNF)- ${alpha}$ -induced Osteoclast Differentiation by Down-regulation of Expression of TNF Receptors 1 and 2
J. Biol. Chem. 2005 280: 11759-11769. First Published on January 14, 2005; doi:10.1074/jbc.M410828200 [Abstract] [Full Text] [PDF]

Elena Shirokova, Kristin Schmiedeberg, Peter Bedner, Heiner Niessen, Klaus Willecke, Jan-Dirk Raguse, Wolfgang Meyerhof, and Dietmar Krautwurst: Identification of Specific Ligands for Orphan Olfactory Receptors: G PROTEIN-DEPENDENT AGONISM AND ANTAGONISM OF ODORANTS
J. Biol. Chem. 2005 280: 11807-11815. First Published on December 14, 2004; doi:10.1074/jbc.M411508200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lilly Y. W. Bourguignon, Eli Gilad, Kori Rothman, and Karine Peyrollier: Hyaluronan-CD44 Interaction with IQGAP1 Promotes Cdc42 and ERK Signaling, Leading to Actin Binding, Elk-1/Estrogen Receptor Transcriptional Activation, and Ovarian Cancer Progression
J. Biol. Chem. 2005 280: 11961-11972. First Published on January 17, 2005; doi:10.1074/jbc.M411985200 [Abstract] [Full Text] [PDF]

Jung Jin Hwang, Mi-Ha Park, So-Young Choi, and Jae-Young Koh: Activation of the Trk Signaling Pathway by Extracellular Zinc: ROLE OF METALLOPROTEINASES
J. Biol. Chem. 2005 280: 11995-12001. First Published on January 19, 2005; doi:10.1074/jbc.M403172200 [Abstract] [Full Text] [PDF]

Roya Zoraghi, Emmanuel P. Bessay, Jackie D. Corbin, and Sharron H. Francis: Structural and Functional Features in Human PDE5A1 Regulatory Domain That Provide for Allosteric cGMP Binding, Dimerization, and Regulation
J. Biol. Chem. 2005 280: 12051-12063. First Published on January 27, 2005; doi:10.1074/jbc.M413611200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Miki Tsukada, Alexander Prokscha, Ernst Ungewickell, and Gregor Eichele: Doublecortin Association with Actin Filaments Is Regulated by Neurabin II
J. Biol. Chem. 2005 280: 11361-11368. First Published on January 4, 2005; doi:10.1074/jbc.M405525200 [Abstract] [Full Text] [PDF]

Olivier Bezy, Christian Elabd, Olivia Cochet, Rasmus K. Petersen, Karsten Kristiansen, Christian Dani, Gérard Ailhaud, and Ez-Zoubir Amri: Delta-interacting Protein A, a New Inhibitory Partner of CCAAT/Enhancer-binding Protein ${beta}$ , Implicated in Adipocyte Differentiation
J. Biol. Chem. 2005 280: 11432-11438. First Published on January 11, 2005; doi:10.1074/jbc.M411741200 [Abstract] [Full Text] [PDF]

Wendi Roscoe, Gregory I. L. Veitch, Xiang-Qun Gong, Emily Pellegrino, Donglin Bai, Elizabeth McLachlan, Qing Shao, Gerald M. Kidder, and Dale W. Laird: Oculodentodigital Dysplasia-causing Connexin43 Mutants Are Non-functional and Exhibit Dominant Effects on Wild-type Connexin43
J. Biol. Chem. 2005 280: 11458-11466. First Published on January 10, 2005; doi:10.1074/jbc.M409564200 [Abstract] [Full Text] [PDF]

Anita Woods, Guoyan Wang, and Frank Beier: RhoA/ROCK Signaling Regulates Sox9 Expression and Actin Organization during Chondrogenesis
J. Biol. Chem. 2005 280: 11626-11634. First Published on January 21, 2005; doi:10.1074/jbc.M409158200 [Abstract] [Full Text] [PDF]

Kenneth J. Mandell, Brian A. Babbin, Asma Nusrat, and Charles A. Parkos: Junctional Adhesion Molecule 1 Regulates Epithelial Cell Morphology through Effects on ${beta}$ 1 Integrins and Rap1 Activity
J. Biol. Chem. 2005 280: 11665-11674. First Published on January 27, 2005; doi:10.1074/jbc.M412650200 [Abstract] [Full Text] [PDF]

Erika S. Wittchen, Rebecca A. Worthylake, Patrick Kelly, Patrick J. Casey, Lawrence A. Quilliam, and Keith Burridge: Rap1 GTPase Inhibits Leukocyte Transmigration by Promoting Endothelial Barrier Function
J. Biol. Chem. 2005 280: 11675-11682. First Published on January 20, 2005; doi:10.1074/jbc.M412595200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jong In Yook, Xiao-Yan Li, Ichiro Ota, Eric R. Fearon, and Stephen J. Weiss: Wnt-dependent Regulation of the E-cadherin Repressor Snail
J. Biol. Chem. 2005 280: 11740-11748. First Published on January 11, 2005; doi:10.1074/jbc.M413878200 [Abstract] [Full Text] [PDF]

Reshma Rangwala, Fatima Banine, Jean-Paul Borg, and Larry S. Sherman: Erbin Regulates Mitogen-activated Protein (MAP) Kinase Activation and MAP Kinase-dependent Interactions between Merlin and Adherens Junction Protein Complexes in Schwann Cells
J. Biol. Chem. 2005 280: 11790-11797. First Published on January 19, 2005; doi:10.1074/jbc.M414154200 [Abstract] [Full Text] [PDF]

Matthew R. Barron, Narasimhaswamy S. Belaguli, Shu Xiang Zhang, Mimi Trinh, Dinaker Iyer, Xanthi Merlo, John W. Lough, Michael S. Parmacek, Benoit G. Bruneau, and Robert J. Schwartz: Serum Response Factor, an Enriched Cardiac Mesoderm Obligatory Factor, Is a Downstream Gene Target for Tbx Genes
J. Biol. Chem. 2005 280: 11816-11828. First Published on December 9, 2004; doi:10.1074/jbc.M412408200 [Abstract] [Full Text] [PDF]

Shanta Sarfare, Syed Tariq Ahmad, Michelle V. Joyce, Bill Boggess, and Joseph E. O'Tousa: The Drosophila ninaG Oxidoreductase Acts in Visual Pigment Chromophore Production
J. Biol. Chem. 2005 280: 11895-11901. First Published on January 7, 2005; doi:10.1074/jbc.M412236200 [Abstract] [Full Text] [PDF]

Zoé E. Kilpatrick, Dimitrios Cakouros, and Sharad Kumar: Ecdysone-mediated Up-regulation of the Effector Caspase DRICE Is Required for Hormone-dependent Apoptosis in Drosophila Cells
J. Biol. Chem. 2005 280: 11981-11986. First Published on January 18, 2005; doi:10.1074/jbc.M413971200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Joseph R. Marszalek, Claire Kitidis, Ariya Dararutana, and Harvey F. Lodish: Acyl-CoA synthetase 2 overexpression enhances fatty acid internalization and neurite outgrowth. Vol. 279 (2004) 23882-23891
J. Biol. Chem. 2005 280: 12064. [Full Text] [PDF]

Cuong Vuong, Stanislava Kocianova, Jovanka M. Voyich, Yufeng Yao, Elizabeth R. Fischer, Frank R. DeLeo, and Michael Otto: A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence. Vol. 279 (2004) 54881-54886
J. Biol. Chem. 2005 280: 12064-a. [Full Text] [PDF]

Nerbil Kilic, Leticia Oliviera-Ferrer, Jan-Henner Wurmbach, Sonja Loges, Fariba Chalajour, Samira Neshat-Vahid, Joachim Weil, Malkanthi Fernando, and Suleyman Ergun: Pro-angiogenic signaling by the endothelial presence of CEACAM1. Vol. 280 (2005) 2361-2369
J. Biol. Chem. 2005 280: 12064-b. [Full Text] [PDF]

Xiang-Qun Xie and Jian-Zhong Chen: NMR structural comparison of the cytoplasmic juxtamembrane domains of G-protein-coupled CB₁ and CB₂ receptors in membrane mimetic dodecylphosphocholine micelles. Vol. 280 (2005) 3605-3612
J. Biol. Chem. 2005 280: 12064-c. [Full Text] [PDF]

Ariel Mizrahi, Shahar Molshanski-Mor, Carolyn Weinbaum, Yi Zheng, Miriam Hirshberg, and Edgar Pick: Activation of the phagocyte NADPH oxidase by Rac guanine nucleotide exchange factors in conjunction with ATP and nucleoside diphosphate kinase. Vol. 280 (2005) 3802-3811
J. Biol. Chem. 2005 280: 12064-d. [Full Text] [PDF]