JBC INTERFERin siRNA transfection reagent

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Table of Contents: Apr 8 2005; 280 (14)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption]
      Down Papers Of The Week
      Down Classics
      Down Minireviews
      Down Accelerated Publications
      Down DNA: Replication, Repair, and Recombination
      Down Genes: Structure and Regulation
      Down RNA: Structure, Metabolism, and Catalysis
      Down Protein Synthesis, Post-Translation Modification, and Degradation
      Down Protein Structure and Folding
      Down Enzyme Catalysis and Regulation
      Down Metabolism and Bioenergetics
      Down Glycobiology and Extracellular Matrices
      Down Lipids and Lipoproteins
      Down Membrane Transport, Structure, Function, and Biogenesis
      Down Mechanisms Of Signal Transduction
      Down Molecular Basis Of Cell and Developmental Biology
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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Papers Of The Week:Back

Activating NADPH Oxidase
J. Biol. Chem. 2005 280: e99915. [Full Text]  

Reassigning the Role of a Tuberculosis Protein
J. Biol. Chem. 2005 280: e99916. [Full Text]  


Classics:Back

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
The ATP Requirement for Fatty Acid Oxidation: the Early Work of Albert L. Lehninger
THE RELATIONSHIP OF THE ADENOSINE POLYPHOSPHATES TO FATTY ACID OXIDATION IN HOMOGENIZED LIVER PREPARATIONS (Albert L. Lehninger J. Biol. Chem. 157, 363-382)
J. Biol. Chem. 2005 280: e11. [Full Text]  


Minireviews:Back

Enrique Rozengurt, Osvaldo Rey, and Richard T. Waldron
Protein Kinase D Signaling
J. Biol. Chem. 2005 280: 13205-13208. First Published on February 8, 2005; doi:10.1074/jbc.R500002200 [Full Text] [PDF]  


Accelerated Publications:Back

Ming Liu, Yulin Li, Douglas Cavener, and Peter Arvan
Proinsulin Disulfide Maturation and Misfolding in the Endoplasmic Reticulum
J. Biol. Chem. 2005 280: 13209-13212. First Published on February 10, 2005; doi:10.1074/jbc.C400475200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:Back

Stanislav N. Naryzhny, Helen Zhao, and Hoyun Lee
Proliferating Cell Nuclear Antigen (PCNA) May Function as a Double Homotrimer Complex in the Mammalian Cell
J. Biol. Chem. 2005 280: 13888-13894. First Published on February 1, 2005; doi:10.1074/jbc.M500304200 [Abstract] [Full Text] [PDF]  

Geoffrey S. Briggs, Akeel A. Mahdi, Qin Wen, and Robert G. Lloyd
DNA Binding by the Substrate Specificity (Wedge) Domain of RecG Helicase Suggests a Role in Processivity
J. Biol. Chem. 2005 280: 13921-13927. First Published on February 3, 2005; doi:10.1074/jbc.M412054200 [Abstract] [Full Text] [PDF]  

Elisabetta Leo, Katherine A. Gould, Xiao-Su Pan, Giovanni Capranico, Mark R. Sanderson, Manlio Palumbo, and L. Mark Fisher
Novel Symmetric and Asymmetric DNA Scission Determinants for Streptococcus pneumoniae Topoisomerase IV and Gyrase Are Clustered at the DNA Breakage Site
J. Biol. Chem. 2005 280: 14252-14263. First Published on January 18, 2005; doi:10.1074/jbc.M500156200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:Back

Robert A. Johnson, Erica M. Shepard, and Kathleen W. Scotto
Differential Regulation of MDR1 Transcription by the p53 Family Members: ROLE OF THE DNA BINDING DOMAIN
J. Biol. Chem. 2005 280: 13213-13219. First Published on January 5, 2005; doi:10.1074/jbc.M414646200 [Abstract] [Full Text] [PDF]  

Christine Yu, Kathleen Markan, Karla A. Temple, Dianne Deplewski, Matthew J. Brady, and Ronald N. Cohen
The Nuclear Receptor Corepressors NCoR and SMRT Decrease Peroxisome Proliferator-activated Receptor {gamma} Transcriptional Activity and Repress 3T3-L1 Adipogenesis
J. Biol. Chem. 2005 280: 13600-13605. First Published on February 3, 2005; doi:10.1074/jbc.M409468200 [Abstract] [Full Text] [PDF]  

Anna Testa, Giacomo Donati, Pearlly Yan, Francesca Romani, Tim H.-M. Huang, M. Alessandra Viganò, and Roberto Mantovani
Chromatin Immunoprecipitation (ChIP) on Chip Experiments Uncover a Widespread Distribution of NF-Y Binding CCAAT Sites Outside of Core Promoters
J. Biol. Chem. 2005 280: 13606-13615. First Published on January 11, 2005; doi:10.1074/jbc.M414039200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Mainul Hoque, Bin Tian, Michael B. Mathews, and Tsafi Pe'ery
Granulin and Granulin Repeats Interact with the Tat·P-TEFb Complex and Inhibit Tat Transactivation
J. Biol. Chem. 2005 280: 13648-13657. First Published on January 14, 2005; doi:10.1074/jbc.M409575200 [Abstract] [Full Text] [PDF]  

Yong Cai, Jingji Jin, Laurence Florens, Selene K. Swanson, Thomas Kusch, Bing Li, Jerry L. Workman, Michael P. Washburn, Ronald C. Conaway, and Joan Weliky Conaway
The Mammalian YL1 Protein Is a Shared Subunit of the TRRAP/TIP60 Histone Acetyltransferase and SRCAP Complexes
J. Biol. Chem. 2005 280: 13665-13670. First Published on January 11, 2005; doi:10.1074/jbc.M500001200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Mélanie Béland and David Lohnes
Chicken Ovalbumin Upstream Promoter-Transcription Factor Members Repress Retinoic Acid-induced Cdx1 Expression
J. Biol. Chem. 2005 280: 13858-13862. First Published on January 26, 2005; doi:10.1074/jbc.M412981200 [Abstract] [Full Text] [PDF]  

Xubin Zhou, Rong Wang, Libin Fan, Yan Li, Li Ma, Zhenye Yang, Wei Yu, Naihe Jing, and Xueliang Zhu
Mitosin/CENP-F as a Negative Regulator of Activating Transcription Factor-4
J. Biol. Chem. 2005 280: 13973-13977. First Published on January 26, 2005; doi:10.1074/jbc.M414310200 [Abstract] [Full Text] [PDF]  

Lucie Canaff and Geoffrey N. Hendy
Calcium-sensing Receptor Gene Transcription Is Up-regulated by the Proinflammatory Cytokine, Interleukin-1{beta}: ROLE OF THE NF-{kappa}B PATHWAY AND {kappa}B ELEMENTS
J. Biol. Chem. 2005 280: 14177-14188. First Published on January 31, 2005; doi:10.1074/jbc.M408587200 [Abstract] [Full Text] [PDF]  

Yingzi Wang, Junning Wang, Lei Gao, Robert Lafyatis, Stefan Stamm, and Athena Andreadis
Tau Exons 2 and 10, Which Are Misregulated in Neurodegenerative Diseases, Are Partly Regulated by Silencers Which Bind a SRp30c·SRp55 Complex That Either Recruits or Antagonizes htra2{beta}1
J. Biol. Chem. 2005 280: 14230-14239. First Published on February 3, 2005; doi:10.1074/jbc.M413846200 [Abstract] [Full Text] [PDF]  

Cameron P. Bracken, Murray L. Whitelaw, and Daniel J. Peet
Activity of Hypoxia-inducible Factor 2{alpha} Is Regulated by Association with the NF-{kappa}B Essential Modulator
J. Biol. Chem. 2005 280: 14240-14251. First Published on January 13, 2005; doi:10.1074/jbc.M409987200 [Abstract] [Full Text] [PDF]  

Ming-Chang Chiang, Yi-Chao Lee, Chuen-Lin Huang, and Yijuang Chern
cAMP-response Element-binding Protein Contributes to Suppression of the A2A Adenosine Receptor Promoter by Mutant Huntingtin with Expanded Polyglutamine Residues
J. Biol. Chem. 2005 280: 14331-14340. First Published on February 2, 2005; doi:10.1074/jbc.M413279200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


RNA: Structure, Metabolism, and Catalysis:Back

Eric J. Wagner, Andrew P. Baraniak, October M. Sessions, David Mauger, Eric Moskowitz, and Mariano A. Garcia-Blanco
Characterization of the Intronic Splicing Silencers Flanking FGFR2 Exon IIIb
J. Biol. Chem. 2005 280: 14017-14027. First Published on January 31, 2005; doi:10.1074/jbc.M414492200 [Abstract] [Full Text] [PDF]  

Ryohei Ishii, Asako Minagawa, Hiroaki Takaku, Masamichi Takagi, Masayuki Nashimoto, and Shigeyuki Yokoyama
Crystal Structure of the tRNA 3' Processing Endoribonuclease tRNase Z from Thermotoga maritima
J. Biol. Chem. 2005 280: 14138-14144. First Published on January 27, 2005; doi:10.1074/jbc.M500355200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:Back

Xin Wang, Qi-Quan Huang, Mark T. Breckenridge, Aihua Chen, Thomas O. Crawford, D. Holmes Morton, and Jian-Ping Jin
Cellular Fate of Truncated Slow Skeletal Muscle Troponin T Produced by Glu180 Nonsense Mutation in Amish Nemaline Myopathy
J. Biol. Chem. 2005 280: 13241-13249. First Published on January 23, 2005; doi:10.1074/jbc.M413696200 [Abstract] [Full Text] [PDF]  

Carole Gwizdek, Maria Hobeika, Bart Kus, Batool Ossareh-Nazari, Catherine Dargemont, and Manuel S. Rodriguez
The mRNA Nuclear Export Factor Hpr1 Is Regulated by Rsp5-mediated Ubiquitylation
J. Biol. Chem. 2005 280: 13401-13405. First Published on February 15, 2005; doi:10.1074/jbc.C500040200 [Abstract] [Full Text] [PDF]  

John H. Connor and Douglas S. Lyles
Inhibition of Host and Viral Translation during Vesicular Stomatitis Virus Infection: eIF2 IS RESPONSIBLE FOR THE INHIBITION OF VIRAL BUT NOT HOST TRANSLATION
J. Biol. Chem. 2005 280: 13512-13519. First Published on February 10, 2005; doi:10.1074/jbc.M501156200 [Abstract] [Full Text] [PDF]  

Ghada Abboud-Jarrous, Zehava Rangini-Guetta, Helena Aingorn, Ruth Atzmon, Sharona Elgavish, Tamar Peretz, and Israel Vlodavsky
Site-directed Mutagenesis, Proteolytic Cleavage, and Activation of Human Proheparanase
J. Biol. Chem. 2005 280: 13568-13575. First Published on January 19, 2005; doi:10.1074/jbc.M413370200 [Abstract] [Full Text] [PDF]  

Maribel Parra, Herbert Kasler, Timothy A. McKinsey, Eric N. Olson, and Eric Verdin
Protein Kinase D1 Phosphorylates HDAC7 and Induces Its Nuclear Export after T-cell Receptor Activation
J. Biol. Chem. 2005 280: 13762-13770. First Published on December 28, 2004; doi:10.1074/jbc.M413396200 [Abstract] [Full Text] [PDF]  

Costin I. Popescu, Crina Paduraru, Raymond A. Dwek, and Stefana M. Petrescu
Soluble Tyrosinase is an Endoplasmic Reticulum (ER)-associated Degradation Substrate Retained in the ER by Calreticulin and BiP/GRP78 and Not Calnexin
J. Biol. Chem. 2005 280: 13833-13840. First Published on January 27, 2005; doi:10.1074/jbc.M413087200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Toshihiko Hoashi, Hidenori Watabe, Jacqueline Muller, Yuji Yamaguchi, Wilfred D. Vieira, and Vincent J. Hearing
MART-1 Is Required for the Function of the Melanosomal Matrix Protein PMEL17/GP100 and the Maturation of Melanosomes
J. Biol. Chem. 2005 280: 14006-14016. First Published on January 28, 2005; doi:10.1074/jbc.M413692200 [Abstract] [Full Text] [PDF]  

Hao-Yuan Jiang and Ronald C. Wek
Phosphorylation of the {alpha}-Subunit of the Eukaryotic Initiation Factor-2 (eIF2{alpha}) Reduces Protein Synthesis and Enhances Apoptosis in Response to Proteasome Inhibition
J. Biol. Chem. 2005 280: 14189-14202. First Published on January 31, 2005; doi:10.1074/jbc.M413660200 [Abstract] [Full Text] [PDF]  

Araceli Díaz-Perales, Víctor Quesada, Luis M. Sánchez, Alejandro P. Ugalde, María F. Suárez, Antonio Fueyo, and Carlos López-Otín
Identification of Human Aminopeptidase O, a Novel Metalloprotease with Structural Similarity to Aminopeptidase B and Leukotriene A4 Hydrolase
J. Biol. Chem. 2005 280: 14310-14317. First Published on February 1, 2005; doi:10.1074/jbc.M413222200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:Back

Alexis Nazabal, Marie-Lise Maddelein, Marc Bonneu, Sven J. Saupe, and Jean-Marie Schmitter
Probing the Structure of the Infectious Amyloid Form of the Prion-forming Domain of HET-s Using High Resolution Hydrogen/Deuterium Exchange Monitored by Mass Spectrometry
J. Biol. Chem. 2005 280: 13220-13228. First Published on January 12, 2005; doi:10.1074/jbc.M413185200 [Abstract] [Full Text] [PDF]  

Henri R. Nordlund, Vesa P. Hytönen, Olli H. Laitinen, and Markku S. Kulomaa
Novel Avidin-like Protein from a Root Nodule Symbiotic Bacterium, Bradyrhizobium japonicum
J. Biol. Chem. 2005 280: 13250-13255. First Published on January 28, 2005; doi:10.1074/jbc.M414336200 [Abstract] [Full Text] [PDF]  

Chuan-Peng Liu, Sarah Perrett, and Jun-Mei Zhou
Dimeric Trigger Factor Stably Binds Folding-competent Intermediates and Cooperates with the DnaK-DnaJ-GrpE Chaperone System to Allow Refolding
J. Biol. Chem. 2005 280: 13315-13320. First Published on January 4, 2005; doi:10.1074/jbc.M414151200 [Abstract] [Full Text] [PDF]  

Anna K. Tickler, Danielle G. Smith, Giuseppe D. Ciccotosto, Deborah J. Tew, Cyril C. Curtain, Darryl Carrington, Colin L. Masters, Ashley I. Bush, Robert A. Cherny, Roberto Cappai, John D. Wade, and Kevin J. Barnham
Methylation of the Imidazole Side Chains of the Alzheimer Disease Amyloid-{beta} Peptide Results in Abolition of Superoxide Dismutase-like Structures and Inhibition of Neurotoxicity
J. Biol. Chem. 2005 280: 13355-13363. First Published on January 24, 2005; doi:10.1074/jbc.M414178200 [Abstract] [Full Text] [PDF]  

LaToya S. Jones, Laura J. Peek, Jonathan Power, Aaron Markham, Brian Yazzie, and C. Russell Middaugh
Effects of Adsorption to Aluminum Salt Adjuvants on the Structure and Stability of Model Protein Antigens
J. Biol. Chem. 2005 280: 13406-13414. First Published on January 31, 2005; doi:10.1074/jbc.M500687200 [Abstract] [Full Text] [PDF]  

Tong-Jin Zhao, Wen-Bin Ou, Qiang Xie, Yang Liu, Yong-Bin Yan, and Hai-Meng Zhou
Catalysis of Creatine Kinase Refolding by Protein Disulfide Isomerase Involves Disulfide Cross-link and Dimer to Tetramer Switch
J. Biol. Chem. 2005 280: 13470-13476. First Published on February 5, 2005; doi:10.1074/jbc.M413882200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Veronique M. Hermann, John F. Cutfield, and Michael J. Hubbard
Biophysical Characterization of ERp29: EVIDENCE FOR A KEY STRUCTURAL ROLE OF CYSTEINE 125
J. Biol. Chem. 2005 280: 13529-13537. First Published on November 30, 2004; doi:10.1074/jbc.M410889200 [Abstract] [Full Text] [PDF]  

Xueyan Ma, Juergen Koepke, Santosh Panjikar, Günter Fritzsch, and Joachim Stöckigt
Crystal Structure of Vinorine Synthase, the First Representative of the BAHD Superfamily
J. Biol. Chem. 2005 280: 13576-13583. First Published on January 22, 2005; doi:10.1074/jbc.M414508200 [Abstract] [Full Text] [PDF]  

HaJeung Park, Floyd G. Adsit, and Jeffrey C. Boyington
The 1.4 Å Crystal Structure of the Human Oxidized Low Density Lipoprotein Receptor Lox-1
J. Biol. Chem. 2005 280: 13593-13599. First Published on February 5, 2005; doi:10.1074/jbc.M500768200 [Abstract] [Full Text] [PDF]  

Mário T. Murakami, Matheus F. Fernandes-Pedrosa, Denise V. Tambourgi, and Raghuvir K. Arni
Structural Basis for Metal Ion Coordination and the Catalytic Mechanism of Sphingomyelinases D
J. Biol. Chem. 2005 280: 13658-13664. First Published on January 14, 2005; doi:10.1074/jbc.M412437200 [Abstract] [Full Text] [PDF]  

Júlio C. Borges, Hannes Fischer, Aldo F. Craievich, and Carlos H. I. Ramos
Low Resolution Structural Study of Two Human HSP40 Chaperones in Solution: DJA1 FROM SUBFAMILY A AND DJB4 FROM SUBFAMILY B HAVE DIFFERENT QUATERNARY STRUCTURES
J. Biol. Chem. 2005 280: 13671-13681. First Published on January 20, 2005; doi:10.1074/jbc.M408349200 [Abstract] [Full Text] [PDF]  

Kivanc Bilecen, Umit H. Ozturk, Adil D. Duru, Tolga Sutlu, Maxim V. Petoukhov, Dimitri I. Svergun, Michel H. J. Koch, Ugur O. Sezerman, Ismail Cakmak, and Zehra Sayers
Triticum durum Metallothionein: ISOLATION OF THE GENE AND STRUCTURAL CHARACTERIZATION OF THE PROTEIN USING SOLUTION SCATTERING AND MOLECULAR MODELING
J. Biol. Chem. 2005 280: 13701-13711. First Published on January 4, 2005; doi:10.1074/jbc.M412984200 [Abstract] [Full Text] [PDF]  

Priyamvada Acharya, Meike Goenrich, Christoph H. Hagemeier, Ulrike Demmer, Julia A. Vorholt, Rudolf K. Thauer, and Ulrich Ermler
How an Enzyme Binds the C1 Carrier Tetrahydromethanopterin: STRUCTURE OF THE TETRAHYDROMETHANOPTERIN-DEPENDENT FORMALDEHYDE-ACTIVATING ENZYME (Fae) FROM METHYLOBACTERIUM EXTORQUENS AM1
J. Biol. Chem. 2005 280: 13712-13719. First Published on January 4, 2005; doi:10.1074/jbc.M412320200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Marc D. Jacobs, James Black, Olga Futer, Lora Swenson, Brian Hare, Mark Fleming, and Kumkum Saxena
Pim-1 Ligand-bound Structures Reveal the Mechanism of Serine/Threonine Kinase Inhibition by LY294002
J. Biol. Chem. 2005 280: 13728-13734. First Published on January 17, 2005; doi:10.1074/jbc.M413155200 [Abstract] [Full Text] [PDF]  

Maki Onda, Didier Belorgey, Lynda K. Sharp, and David A. Lomas
Latent S49P Neuroserpin Forms Polymers in the Dementia Familial Encephalopathy with Neuroserpin Inclusion Bodies
J. Biol. Chem. 2005 280: 13735-13741. First Published on January 21, 2005; doi:10.1074/jbc.M413282200 [Abstract] [Full Text] [PDF]  

Claire Massenet, Sylvie Chenavas, Claudine Cohen-Addad, Marie-Claire Dagher, Gérard Brandolin, Eva Pebay-Peyroula, and Franck Fieschi
Effects of p47phox C Terminus Phosphorylations on Binding Interactions with p40phox and p67phox: STRUCTURAL AND FUNCTIONAL COMPARISON OF p40phox and p67phox SH3 DOMAINS
J. Biol. Chem. 2005 280: 13752-13761. First Published on January 18, 2005; doi:10.1074/jbc.M412897200 [Abstract] [Full Text] [PDF] [Summary]  

Delia Picone, Anna Di Fiore, Carmine Ercole, Marisa Franzese, Filomena Sica, Simona Tomaselli, and Lelio Mazzarella
The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE
J. Biol. Chem. 2005 280: 13771-13778. First Published on January 12, 2005; doi:10.1074/jbc.M413157200 [Abstract] [Full Text] [PDF]  

Rukman S. De Silva, Gabriela Kovacikova, Wei Lin, Ronald K. Taylor, Karen Skorupski, and F. Jon Kull
Crystal Structure of the Virulence Gene Activator AphA from Vibrio cholerae Reveals It Is a Novel Member of the Winged Helix Transcription Factor Superfamily
J. Biol. Chem. 2005 280: 13779-13783. First Published on January 12, 2005; doi:10.1074/jbc.M413781200 [Abstract] [Full Text] [PDF]  

Claire Gondeau, Sabine Gerbal-Chaloin, Paul Bello, Gudrun Aldrian-Herrada, May C. Morris, and Gilles Divita
Design of a Novel Class of Peptide Inhibitors of Cyclin-dependent Kinase/Cyclin Activation
J. Biol. Chem. 2005 280: 13793-13800. First Published on January 13, 2005; doi:10.1074/jbc.M413690200 [Abstract] [Full Text] [PDF]  

Heyue Zhou, Yingqi Xu, Yuedong Yang, Anding Huang, Jihui Wu, and Yunyu Shi
Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr
J. Biol. Chem. 2005 280: 13841-13847. First Published on January 31, 2005; doi:10.1074/jbc.M411065200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Faoud T. Ishmael, Vincent K. Shier, Susan S. Ishmael, and Judith S. Bond
Intersubunit and Domain Interactions of the Meprin B Metalloproteinase: DISULFIDE BONDS AND PROTEIN-PROTEIN INTERACTIONS IN THE MAM AND TRAF DOMAINS
J. Biol. Chem. 2005 280: 13895-13901. First Published on February 4, 2005; doi:10.1074/jbc.M414218200 [Abstract] [Full Text] [PDF]  

David K. Wilson, David Cerna, and Erin Chew
The 1.1-Å Structure of the Spindle Checkpoint Protein Bub3p Reveals Functional Regions
J. Biol. Chem. 2005 280: 13944-13951. First Published on January 11, 2005; doi:10.1074/jbc.M412919200 [Abstract] [Full Text] [PDF]  

Graeme L. Card, Neil A. Peterson, Clyde A. Smith, Bernhard Rupp, Brian M. Schick, and Edward N. Baker
The Crystal Structure of Rv1347c, a Putative Antibiotic Resistance Protein from Mycobacterium tuberculosis, Reveals a GCN5-related Fold and Suggests an Alternative Function in Siderophore Biosynthesis
J. Biol. Chem. 2005 280: 13978-13986. First Published on January 28, 2005; doi:10.1074/jbc.M413904200 [Abstract] [Full Text] [PDF] [Summary]  

Lars Redecke, Wolfram Meyer-Klaucke, Mirjam Koker, Joachim Clos, Dessislava Georgieva, Nicolay Genov, Hartmut Echner, Hubert Kalbacher, Markus Perbandt, Reinhard Bredehorst, Wolfgang Voelter, and Christian Betzel
Comparative Analysis of the Human and Chicken Prion Protein Copper Binding Regions at pH 6.5
J. Biol. Chem. 2005 280: 13987-13992. First Published on January 30, 2005; doi:10.1074/jbc.M411775200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Erika E. Büllesbach and Christian Schwabe
The Trap-like Relaxin-binding Site of the Leucine-rich G-protein-coupled Receptor 7
J. Biol. Chem. 2005 280: 14051-14056. First Published on February 4, 2005; doi:10.1074/jbc.M500030200 [Abstract] [Full Text] [PDF]  

Sacha A. Jensen, Adam R. Corbett, Vroni Knott, Christina Redfield, and Penny A. Handford
Ca2+-dependent Interface Formation in Fibrillin-1
J. Biol. Chem. 2005 280: 14076-14084. First Published on January 13, 2005; doi:10.1074/jbc.M412832200 [Abstract] [Full Text] [PDF]  

Erwin De Genst, Karen Silence, Mehdi Arbabi Ghahroudi, Klaas Decanniere, Remy Loris, Jörg Kinne, Lode Wyns, and Serge Muyldermans
Strong in Vivo Maturation Compensates for Structurally Restricted H3 Loops in Antibody Repertoires
J. Biol. Chem. 2005 280: 14114-14121. First Published on January 19, 2005; doi:10.1074/jbc.M413011200 [Abstract] [Full Text] [PDF]  

Takuma Shiraki, Narutoshi Kamiya, Sayaka Shiki, Takashi S. Kodama, Akira Kakizuka, and Hisato Jingami
{alpha},{beta}-Unsaturated Ketone Is a Core Moiety of Natural Ligands for Covalent Binding to Peroxisome Proliferator-activated Receptor {gamma}
J. Biol. Chem. 2005 280: 14145-14153. First Published on February 4, 2005; doi:10.1074/jbc.M500901200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:Back

Paul R. Race, Andrew L. Lovering, Richard M. Green, Abdelmijd Ossor, Scott A. White, Peter F. Searle, Christopher J. Wrighton, and Eva I. Hyde
Structural and Mechanistic Studies of Escherichia coli Nitroreductase with the Antibiotic Nitrofurazone: REVERSED BINDING ORIENTATIONS IN DIFFERENT REDOX STATES OF THE ENZYME
J. Biol. Chem. 2005 280: 13256-13264. First Published on January 31, 2005; doi:10.1074/jbc.M409652200 [Abstract] [Full Text] [PDF]  

Amit V. Pandey and Walter L. Miller
Regulation of 17,20 Lyase Activity by Cytochrome b5 and by Serine Phosphorylation of P450c17
J. Biol. Chem. 2005 280: 13265-13271. First Published on February 1, 2005; doi:10.1074/jbc.M414673200 [Abstract] [Full Text] [PDF]  

Kristin Viste, Reidun K. Kopperud, Anne E. Christensen, and Stein O. Døskeland
Substrate Enhances the Sensitivity of Type I Protein Kinase A to cAMP
J. Biol. Chem. 2005 280: 13279-13284. First Published on February 3, 2005; doi:10.1074/jbc.M413065200 [Abstract] [Full Text] [PDF]  

Rebecca J. Browne, Eric W. Barr, and Barbara L. Stitt
Catalytic Cooperativity among Subunits of Escherichia coli Transcription Termination Factor Rho: KINETICS AND SUBSTRATE STRUCTURAL REQUIREMENTS
J. Biol. Chem. 2005 280: 13292-13299. First Published on February 9, 2005; doi:10.1074/jbc.M500221200 [Abstract] [Full Text] [PDF]  

Rebecca J. Browne and Barbara L. Stitt
Active Site Occupancy Required for Catalytic Cooperativity by Escherichia coli Transcription Termination Factor Rho
J. Biol. Chem. 2005 280: 13300-13303. First Published on February 9, 2005; doi:10.1074/jbc.M500222200 [Abstract] [Full Text] [PDF]  

Humaira Gowher, Kirsten Liebert, Andrea Hermann, Guoliang Xu, and Albert Jeltsch
Mechanism of Stimulation of Catalytic Activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L
J. Biol. Chem. 2005 280: 13341-13348. First Published on January 24, 2005; doi:10.1074/jbc.M413412200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Samanta Raboni, Stefano Bettati, and Andrea Mozzarelli
Identification of the Geometric Requirements for Allosteric Communication between the {alpha}- and {beta}-Subunits of Tryptophan Synthase
J. Biol. Chem. 2005 280: 13450-13456. First Published on February 3, 2005; doi:10.1074/jbc.M414521200 [Abstract] [Full Text] [PDF]  

Richard T. Eastman, John White, Oliver Hucke, Kevin Bauer, Kohei Yokoyama, Laxman Nallan, Debopam Chakrabarti, Christophe L. M. J. Verlinde, Michael H. Gelb, Pradipsinh K. Rathod, and Wesley C. Van Voorhis
Resistance to a Protein Farnesyltransferase Inhibitor in Plasmodium falciparum
J. Biol. Chem. 2005 280: 13554-13559. First Published on January 20, 2005; doi:10.1074/jbc.M413556200 [Abstract] [Full Text] [PDF]  

Katja Schneider, Lucie Kienow, Elmon Schmelzer, Thomas Colby, Michael Bartsch, Otto Miersch, Claus Wasternack, Erich Kombrink, and Hans-Peter Stuible
A New Type of Peroxisomal Acyl-Coenzyme A Synthetase from Arabidopsis thaliana Has the Catalytic Capacity to Activate Biosynthetic Precursors of Jasmonic Acid
J. Biol. Chem. 2005 280: 13962-13972. First Published on January 26, 2005; doi:10.1074/jbc.M413578200 [Abstract] [Full Text] [PDF]  

Susanne Eschenburg, Melanie A. Priestman, Farid A. Abdul-Latif, Carole Delachaume, Florence Fassy, and Ernst Schönbrunn
A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA)
J. Biol. Chem. 2005 280: 14070-14075. First Published on February 8, 2005; doi:10.1074/jbc.M414412200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Anna L. Gloyn, Stella Odili, Dorothy Zelent, Carol Buettger, Harriet A. J. Castleden, Anna M. Steele, Amanda Stride, Chyio Shiota, Mark A. Magnuson, Renata Lorini, Giuseppe d'Annunzio, Charles A. Stanley, Jae Kwagh, Emile van Schaftingen, Maria Veiga-da-Cunha, Fabrizio Barbetti, Pete Dunten, Yi Han, Joseph Grimsby, Rebecca Taub, Sian Ellard, Andrew T. Hattersley, and Franz M. Matschinsky
Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young
J. Biol. Chem. 2005 280: 14105-14113. First Published on January 25, 2005; doi:10.1074/jbc.M413146200 [Abstract] [Full Text] [PDF]  

Steven D. Breazeale, Anthony A. Ribeiro, Amanda L. McClerren, and Christian R. H. Raetz
A Formyltransferase Required for Polymyxin Resistance in Escherichia coli and the Modification of Lipid A with 4-Amino-4-deoxy-L-arabinose: IDENTIFICATION AND FUNCTION OF UDP-4-DEOXY-4-FORMAMIDO-L-ARABINOSE
J. Biol. Chem. 2005 280: 14154-14167. First Published on January 28, 2005; doi:10.1074/jbc.M414265200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Ritsuko Narasaki, Harushige Kuribayashi, Kosuke Shimizu, Daisuke Imamura, Tsutomu Sato, and Keiji Hasumi
Bacillolysin MA, a Novel Bacterial Metalloproteinase That Produces Angiostatin-like Fragments from Plasminogen and Activates Protease Zymogens in the Coagulation and Fibrinolysis Systems
J. Biol. Chem. 2005 280: 14278-14287. First Published on January 27, 2005; doi:10.1074/jbc.M500241200 [Abstract] [Full Text] [PDF]  

Zhen Zou and Haobo Jiang
Manduca sexta Serpin-6 Regulates Immune Serine Proteinases PAP-3 and HP8: cDNA CLONING, PROTEIN EXPRESSION, INHIBITION KINETICS, AND FUNCTION ELUCIDATION
J. Biol. Chem. 2005 280: 14341-14348. First Published on February 3, 2005; doi:10.1074/jbc.M500570200 [Abstract] [Full Text] [PDF]  

Benjamin Dummitt, William S. Micka, and Yie-Hwa Chang
Yeast Glutamine-fructose-6-phosphate Aminotransferase (Gfa1) Requires Methionine Aminopeptidase Activity for Proper Function
J. Biol. Chem. 2005 280: 14356-14360. First Published on February 7, 2005; doi:10.1074/jbc.M501059200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:Back

Catia Barsotti, Rossana Pesi, Michela Giannecchini, and Piero L. Ipata
Evidence for the Involvement of Cytosolic 5'-Nucleotidase (cN-II) in the Synthesis of Guanine Nucleotides from Xanthosine
J. Biol. Chem. 2005 280: 13465-13469. First Published on February 6, 2005; doi:10.1074/jbc.M413347200 [Abstract] [Full Text] [PDF]  

Jenny M. Schulz, Kerry L. Ross, Kerstin Malmstrom, Monty Krieger, and Judith L. Fridovich-Keil
Mediators of Galactose Sensitivity in UDP-Galactose 4'-Epimerase-impaired Mammalian Cells
J. Biol. Chem. 2005 280: 13493-13502. First Published on February 8, 2005; doi:10.1074/jbc.M414045200 [Abstract] [Full Text] [PDF]  

Tong Shi, Fei Wang, Emily Stieren, and Qiang Tong
SIRT3, a Mitochondrial Sirtuin Deacetylase, Regulates Mitochondrial Function and Thermogenesis in Brown Adipocytes
J. Biol. Chem. 2005 280: 13560-13567. First Published on January 14, 2005; doi:10.1074/jbc.M414670200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Hiroki Sugita, Masaki Fujimoto, Takashi Yasukawa, Nobuyuki Shimizu, Michiko Sugita, Shingo Yasuhara, J. A. Jeevendra Martyn, and Masao Kaneki
Inducible Nitric-oxide Synthase and NO Donor Induce Insulin Receptor Substrate-1 Degradation in Skeletal Muscle Cells
J. Biol. Chem. 2005 280: 14203-14211. First Published on February 1, 2005; doi:10.1074/jbc.M411226200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Claire C. Bastie, Zaher Nahlé, Thomas McLoughlin, Karyn Esser, Wenwei Zhang, Terry Unterman, and Nada A. Abumrad
FoxO1 Stimulates Fatty Acid Uptake and Oxidation in Muscle Cells through CD36-dependent and -independent Mechanisms
J. Biol. Chem. 2005 280: 14222-14229. First Published on February 3, 2005; doi:10.1074/jbc.M413625200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:Back

David C. West, Chris G. Rees, Laurence Duchesne, Susannah J. Patey, Carla J. Terry, Jeremy E. Turnbull, Maryse Delehedde, Christian W. Heegaard, Fabrice Allain, Christophe Vanpouille, Dina Ron, and David G. Fernig
Interactions of Multiple Heparin Binding Growth Factors with Neuropilin-1 and Potentiation of the Activity of Fibroblast Growth Factor-2
J. Biol. Chem. 2005 280: 13457-13464. First Published on February 4, 2005; doi:10.1074/jbc.M410924200 [Abstract] [Full Text] [PDF]  

Coralee E. Tye, Graeme K. Hunter, and Harvey A. Goldberg
Identification of the Type I Collagen-binding Domain of Bone Sialoprotein and Characterization of the Mechanism of Interaction
J. Biol. Chem. 2005 280: 13487-13492. First Published on February 8, 2005; doi:10.1074/jbc.M408923200 [Abstract] [Full Text] [PDF]  

Joseph O. Humtsoe, Jiyeun K. Kim, Yi Xu, Douglas R. Keene, Magnus Höök, Slawomir Lukomski, and Kishore K. Wary
A Streptococcal Collagen-like Protein Interacts with the {alpha}2{beta}1 Integrin and Induces Intracellular Signaling
J. Biol. Chem. 2005 280: 13848-13857. First Published on January 12, 2005; doi:10.1074/jbc.M410605200 [Abstract] [Full Text] [PDF]  

Roberto Cappai, Fang Cheng, Giuseppe D. Ciccotosto, B. Elise Needham, Colin L. Masters, Gerd Multhaup, Lars-Åke Fransson, and Katrin Mani
The Amyloid Precursor Protein (APP) of Alzheimer Disease and Its Paralog, APLP2, Modulate the Cu/Zn-Nitric Oxide-catalyzed Degradation of Glypican-1 Heparan Sulfate in Vivo
J. Biol. Chem. 2005 280: 13913-13920. First Published on January 27, 2005; doi:10.1074/jbc.M409179200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:Back

Heidemarie Müllner, Günter Deutsch, Erich Leitner, Elisabeth Ingolic, and Günther Daum
YEH2/YLR020c Encodes a Novel Steryl Ester Hydrolase of the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 13321-13328. First Published on January 4, 2005; doi:10.1074/jbc.M409914200 [Abstract] [Full Text] [PDF]  

Jeremy A. Sellers, Li Hou, Daniel R. Schoenberg, Silvia R. Batistuzzo de Medeiros, Walter Wahli, and Gregory S. Shelness
Microsomal Triglyceride Transfer Protein Promotes the Secretion of Xenopus laevis Vitellogenin A1
J. Biol. Chem. 2005 280: 13902-13905. First Published on January 27, 2005; doi:10.1074/jbc.M500769200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:Back

Runping Wang, Junda Su, Xueren Wang, Hailan Piao, Xiaoli Zhang, Carmen Y. Adams, Ningren Cui, and Chun Jiang
Subunit Stoichiometry of the Kir1.1 Channel in Proton-dependent Gating
J. Biol. Chem. 2005 280: 13433-13441. First Published on February 3, 2005; doi:10.1074/jbc.M411895200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Christian Wahl-Schott, Ludwig Baumann, Xiangang Zong, and Martin Biel
An Arginine Residue in the Pore Region Is a Key Determinant of Chloride Dependence in Cardiac Pacemaker Channels
J. Biol. Chem. 2005 280: 13694-13700. First Published on January 10, 2005; doi:10.1074/jbc.M413197200 [Abstract] [Full Text] [PDF]  

Marios C. Papadopoulos and A. S. Verkman
Aquaporin-4 Gene Disruption in Mice Reduces Brain Swelling and Mortality in Pneumococcal Meningitis
J. Biol. Chem. 2005 280: 13906-13912. First Published on February 4, 2005; doi:10.1074/jbc.M413627200 [Abstract] [Full Text] [PDF]  

Christopher J. R. Loewen and Timothy P. Levine
A Highly Conserved Binding Site in Vesicle-associated Membrane Protein-associated Protein (VAP) for the FFAT Motif of Lipid-binding Proteins
J. Biol. Chem. 2005 280: 14097-14104. First Published on January 24, 2005; doi:10.1074/jbc.M500147200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:Back

Georg W. Mayr, Sabine Windhorst, and Kirsten Hillemeier
Antiproliferative Plant and Synthetic Polyphenolics Are Specific Inhibitors of Vertebrate Inositol-1,4,5-trisphosphate 3-Kinases and Inositol Polyphosphate Multikinase
J. Biol. Chem. 2005 280: 13229-13240. First Published on January 19, 2005; doi:10.1074/jbc.M500545200 [Abstract] [Full Text] [PDF]  

Serge Hardy, Geneviève G. St-Onge, Érik Joly, Yves Langelier, and Marc Prentki
Oleate Promotes the Proliferation of Breast Cancer Cells via the G Protein-coupled Receptor GPR40
J. Biol. Chem. 2005 280: 13285-13291. First Published on February 4, 2005; doi:10.1074/jbc.M410922200 [Abstract] [Full Text] [PDF]  

Bettina A. Dümmler, Camilla Hauge, Joachim Silber, Helger G. Yntema, Lars S. Kruse, Birte Kofoed, Brian A. Hemmings, Dario R. Alessi, and Morten Frödin
Functional Characterization of Human RSK4, a New 90-kDa Ribosomal S6 Kinase, Reveals Constitutive Activation in Most Cell Types
J. Biol. Chem. 2005 280: 13304-13314. First Published on January 4, 2005; doi:10.1074/jbc.M408194200 [Abstract] [Full Text] [PDF]  

Xuesen Dong, Oksana Shylnova, John R. G. Challis, and Stephen J. Lye
Identification and Characterization of the Protein-associated Splicing Factor as a Negative Co-regulator of the Progesterone Receptor
J. Biol. Chem. 2005 280: 13329-13340. First Published on January 24, 2005; doi:10.1074/jbc.M409187200 [Abstract] [Full Text] [PDF]  

Parvinder K. Aley, Karen E. Porter, John P. Boyle, Paul J. Kemp, and Chris Peers
Hypoxic Modulation of Ca2+ Signaling in Human Venous Endothelial Cells: MULTIPLE ROLES FOR REACTIVE OXYGEN SPECIES
J. Biol. Chem. 2005 280: 13349-13354. First Published on January 24, 2005; doi:10.1074/jbc.M413674200 [Abstract] [Full Text] [PDF]  

Virginie Moucadel and Stefan N. Constantinescu
Differential STAT5 Signaling by Ligand-dependent and Constitutively Active Cytokine Receptors
J. Biol. Chem. 2005 280: 13364-13373. First Published on January 26, 2005; doi:10.1074/jbc.M407326200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Erwin Gäbele, Shimon Reif, Shigeki Tsukada, Ramon Bataller, Yutaka Yata, Terry Morris, Laura W. Schrum, David A. Brenner, and Richard A. Rippe
The Role of p70S6K in Hepatic Stellate Cell Collagen Gene Expression and Cell Proliferation
J. Biol. Chem. 2005 280: 13374-13382. First Published on January 26, 2005; doi:10.1074/jbc.M409444200 [Abstract] [Full Text] [PDF]  

Amy Benians, Muriel Nobles, Sherif Hosny, and Andrew Tinker
Regulators of G-protein Signaling Form a Quaternary Complex with the Agonist, Receptor, and G-protein: A NOVEL EXPLANATION FOR THE ACCELERATION OF SIGNALING ACTIVATION KINETICS
J. Biol. Chem. 2005 280: 13383-13394. First Published on January 27, 2005; doi:10.1074/jbc.M410163200 [Abstract] [Full Text] [PDF]  

Tristan J. Iseli, Mark Walter, Bryce J. W. van Denderen, Frosa Katsis, Lee A. Witters, Bruce E. Kemp, Belinda J. Michell, and David Stapleton
AMP-activated Protein Kinase {beta} Subunit Tethers {alpha} and {gamma} Subunits via Its C-terminal Sequence (186–270)
J. Biol. Chem. 2005 280: 13395-13400. First Published on January 28, 2005; doi:10.1074/jbc.M412993200 [Abstract] [Full Text] [PDF]  

Durga Prasanna Mohapatra and Carla Nau
Regulation of Ca2+-dependent Desensitization in the Vanilloid Receptor TRPV1 by Calcineurin and cAMP-dependent Protein Kinase
J. Biol. Chem. 2005 280: 13424-13432. First Published on February 3, 2005; doi:10.1074/jbc.M410917200 [Abstract] [Full Text] [PDF]  

Rizaldy P. Scott, Susanna Eketjäll, Helena Aineskog, and Carlos F. Ibáñez
Distinct Turnover of Alternatively Spliced Isoforms of the RET Kinase Receptor Mediated by Differential Recruitment of the Cbl Ubiquitin Ligase
J. Biol. Chem. 2005 280: 13442-13449. First Published on January 27, 2005; doi:10.1074/jbc.M500507200 [Abstract] [Full Text] [PDF]  

Jinke Cheng, Ling Yu, Dongyu Zhang, Qiaojia Huang, David Spencer, and Bing Su
Dimerization through the Catalytic Domain Is Essential for MEKK2 Activation
J. Biol. Chem. 2005 280: 13477-13482. First Published on February 4, 2005; doi:10.1074/jbc.M414258200 [Abstract] [Full Text] [PDF]  

Jonathan Wharton, Tova Meshulamy, Gino Vallega, and Paul Pilch
Dissociation of Insulin Receptor Expression and Signaling from Caveolin-1 Expression
J. Biol. Chem. 2005 280: 13483-13486. First Published on February 7, 2005; doi:10.1074/jbc.M413891200 [Abstract] [Full Text] [PDF]  

Sailaja Paruchuri, Oliver Broom, Karim Dib, and Anita Sjölander
The Pro-inflammatory Mediator Leukotriene D4 Induces Phosphatidylinositol 3-Kinase and Rac-dependent Migration of Intestinal Epithelial Cells
J. Biol. Chem. 2005 280: 13538-13544. First Published on January 18, 2005; doi:10.1074/jbc.M409811200 [Abstract] [Full Text] [PDF]  

Hong Seok Choi, Bu Young Choi, Yong-Yeon Cho, Feng Zhu, Ann M. Bode, and Zigang Dong
Phosphorylation of Ser28 in Histone H3 Mediated by Mixed Lineage Kinase-like Mitogen-activated Protein Triple Kinase {alpha}
J. Biol. Chem. 2005 280: 13545-13553. First Published on January 31, 2005; doi:10.1074/jbc.M410521200 [Abstract] [Full Text] [PDF]  

Eric Hay, Chi Faucheu, Isabelle Suc-Royer, Robert Touitou, Veronique Stiot, Béatrice Vayssière, Roland Baron, Sergio Roman-Roman, and Georges Rawadi
Interaction between LRP5 and Frat1 Mediates the Activation of the Wnt Canonical Pathway
J. Biol. Chem. 2005 280: 13616-13623. First Published on February 7, 2005; doi:10.1074/jbc.M411999200 [Abstract] [Full Text] [PDF]  

Jason D. Hoffert, Chung-Lin Chou, Robert A. Fenton, and Mark A. Knepper
Calmodulin Is Required for Vasopressin-stimulated Increase in Cyclic AMP Production in Inner Medullary Collecting Duct
J. Biol. Chem. 2005 280: 13624-13630. First Published on February 14, 2005; doi:10.1074/jbc.M500040200 [Abstract] [Full Text] [PDF]  

Enrique Arevalo, David C. Chiara, Stuart A. Forman, Jonathan B. Cohen, and Keith W. Miller
Gating-enhanced Accessibility of Hydrophobic Sites within the Transmembrane Region of the Nicotinic Acetylcholine Receptor's {delta}-Subunit: A TIME-RESOLVED PHOTOLABELING STUDY
J. Biol. Chem. 2005 280: 13631-13640. First Published on January 21, 2005; doi:10.1074/jbc.M413911200 [Abstract] [Full Text] [PDF]  

Dingbo Lin and Dolores J. Takemoto
Oxidative Activation of Protein Kinase C{gamma} through the C1 Domain: EFFECTS ON GAP JUNCTIONS
J. Biol. Chem. 2005 280: 13682-13693. First Published on January 10, 2005; doi:10.1074/jbc.M407762200 [Abstract] [Full Text] [PDF]  

Verónica García Palacios, Lisa J. Robinson, Christopher W. Borysenko, Thomas Lehmann, Sara E. Kalla, and Harry C. Blair
Negative Regulation of RANKL-induced Osteoclastic Differentiation in RAW264.7 Cells by Estrogen and Phytoestrogens
J. Biol. Chem. 2005 280: 13720-13727. First Published on January 11, 2005; doi:10.1074/jbc.M410995200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Ravinder Pannu, Avtar K. Singh, and Inderjit Singh
A Novel Role of Lactosylceramide in the Regulation of Tumor Necrosis Factor {alpha}-mediated Proliferation of Rat Primary Astrocytes: IMPLICATIONS FOR ASTROGLIOSIS FOLLOWING NEUROTRAUMA
J. Biol. Chem. 2005 280: 13742-13751. First Published on January 24, 2005; doi:10.1074/jbc.M411959200 [Abstract] [Full Text] [PDF]  

Emily J. Chenette, Arie Abo, and Channing J. Der
Critical and Distinct Roles of Amino- and Carboxyl-terminal Sequences in Regulation of the Biological Activity of the Chp Atypical Rho GTPase
J. Biol. Chem. 2005 280: 13784-13792. First Published on January 21, 2005; doi:10.1074/jbc.M411300200 [Abstract] [Full Text] [PDF]  

Michelle S. Linggi, Tara L. Burke, B. Blairanne Williams, Anthony Harrington, Rosemary Kraemer, Barbara L. Hempstead, Sung Ok Yoon, and Bruce D. Carter
Neurotrophin Receptor Interacting Factor (NRIF) Is an Essential Mediator of Apoptotic Signaling by the p75 Neurotrophin Receptor
J. Biol. Chem. 2005 280: 13801-13808. First Published on January 24, 2005; doi:10.1074/jbc.M410435200 [Abstract] [Full Text] [PDF]  

Nele Martens, Galit Uzan, Maxime Wery, Robert Hooghe, Elisabeth L. Hooghe-Peters, and Arieh Gertler
Suppressor of Cytokine Signaling 7 Inhibits Prolactin, Growth Hormone, and Leptin Signaling by Interacting with STAT5 or STAT3 and Attenuating Their Nuclear Translocation
J. Biol. Chem. 2005 280: 13817-13823. First Published on January 26, 2005; doi:10.1074/jbc.M411596200 [Abstract] [Full Text] [PDF]  

Zhigang Li, Dean E. McNulty, Katharine J. M. Marler, Louis Lim, Christine Hall, Roland S. Annan, and David B. Sacks
IQGAP1 Promotes Neurite Outgrowth in a Phosphorylation-dependent Manner
J. Biol. Chem. 2005 280: 13871-13878. First Published on January 28, 2005; doi:10.1074/jbc.M413482200 [Abstract] [Full Text] [PDF]  

Elena Tourkina, Pal Gooz, Jaspreet Pannu, Michael Bonner, Dimitri Scholz, Sharon Hacker, Richard M. Silver, Maria Trojanowska, and Stanley Hoffman
Opposing Effects of Protein Kinase C{alpha} and Protein Kinase C{epsilon} on Collagen Expression by Human Lung Fibroblasts Are Mediated via MEK/ERK and Caveolin-1 Signaling
J. Biol. Chem. 2005 280: 13879-13887. First Published on February 3, 2005; doi:10.1074/jbc.M412551200 [Abstract] [Full Text] [PDF]  

Baskaran Govindarajan, Asha Shah, Cynthia Cohen, Rebecca S. Arnold, Jeffrey Schechner, Jun Chung, Arthur M. Mercurio, Rhoda Alani, Byungwoo Ryu, Chun-Yang Fan, Jose M. Cuezva, Marta Martinez, and Jack L. Arbiser
Malignant Transformation of Human Cells by Constitutive Expression of Platelet-derived Growth Factor-BB
J. Biol. Chem. 2005 280: 13936-13943. First Published on February 4, 2005; doi:10.1074/jbc.M500411200 [Abstract] [Full Text] [PDF]  

Samuel M. Pope, Patricia C. Fulkerson, Carine Blanchard, Hiroko Saito Akei, Nikolaos M. Nikolaidis, Nives Zimmermann, Jeffery D. Molkentin, and Marc E. Rothenberg
Identification of a Cooperative Mechanism Involving Interleukin-13 and Eotaxin-2 in Experimental Allergic Lung Inflammation
J. Biol. Chem. 2005 280: 13952-13961. First Published on January 12, 2005; doi:10.1074/jbc.M406037200 [Abstract] [Full Text] [PDF]  

Toshihiko Suzuki, Kenji Nakanishi, Hiroko Tsutsui, Hiroki Iwai, Shizuo Akira, Naohiro Inohara, Mathias Chamaillard, Gabriel Nuñez, and Chihiro Sasakawa
A Novel Caspase-1/Toll-like Receptor 4-independent Pathway of Cell Death Induced by Cytosolic Shigella in Infected Macrophages
J. Biol. Chem. 2005 280: 14042-14050. First Published on February 4, 2005; doi:10.1074/jbc.M414671200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Paul E. Massa, Xiang Li, Adedayo Hanidu, John Siamas, Milena Pariali, Jessica Pareja, Anne G. Savitt, Katrina M. Catron, Jun Li, and Kenneth B. Marcu
Gene Expression Profiling in Conjunction with Physiological Rescues of IKK{alpha}-null Cells with Wild Type or Mutant IKK{alpha} Reveals Distinct Classes of IKK{alpha}/NF-{kappa}B-dependent Genes
J. Biol. Chem. 2005 280: 14057-14069. First Published on February 4, 2005; doi:10.1074/jbc.M414401200 [Abstract] [Full Text] [PDF]  

Tarek A. Samad, Anuradha Rebbapragada, Esther Bell, Ying Zhang, Yisrael Sidis, Sung-Jin Jeong, Jason A. Campagna, Stephen Perusini, David A. Fabrizio, Alan L. Schneyer, Herbert Y. Lin, Ali H. Brivanlou, Liliana Attisano, and Clifford J. Woolf
DRAGON, a Bone Morphogenetic Protein Co-receptor
J. Biol. Chem. 2005 280: 14122-14129. First Published on January 25, 2005; doi:10.1074/jbc.M410034200 [Abstract] [Full Text] [PDF]  

Anthony M. Vertino, Craig M. Bula, Jin-Ran Chen, Maria Almeida, Li Han, Teresita Bellido, Stavroula Kousteni, Anthony W. Norman, and Stavros C. Manolagas
Nongenotropic, Anti-Apoptotic Signaling of 1{alpha},25(OH)2-Vitamin D3 and Analogs through the Ligand Binding Domain of the Vitamin D Receptor in Osteoblasts and Osteocytes: MEDIATION BY Src, PHOSPHATIDYLINOSITOL 3-, AND JNK KINASES
J. Biol. Chem. 2005 280: 14130-14137. First Published on January 25, 2005; doi:10.1074/jbc.M410720200 [Abstract] [Full Text] [PDF]  

Marius Vantler, Evren Caglayan, Wolfram H. Zimmermann, Anselm T. Bäumer, and Stephan Rosenkranz
Systematic Evaluation of Anti-apoptotic Growth Factor Signaling in Vascular Smooth Muscle Cells: ONLY PHOSPHATIDYLINOSITOL 3'-KINASE IS IMPORTANT
J. Biol. Chem. 2005 280: 14168-14176. First Published on January 7, 2005; doi:10.1074/jbc.M413310200 [Abstract] [Full Text] [PDF]  

Tracy Criswell, Meghan Beman, Shinako Araki, Konstantin Leskov, Eva Cataldo, Lindsey D. Mayo, and David A. Boothman
Delayed Activation of Insulin-like Growth Factor-1 Receptor/Src/MAPK/Egr-1 Signaling Regulates Clusterin Expression, a Pro-survival Factor
J. Biol. Chem. 2005 280: 14212-14221. First Published on February 2, 2005; doi:10.1074/jbc.M412569200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Barbara Valentinis, Alessandro Bianchi, Dan Zhou, Arcadi Cipponi, Federica Catalanotti, Vincenzo Russo, and Catia Traversari
Direct Effects of Polymyxin B on Human Dendritic Cells Maturation: THE ROLE OF I{kappa}B-{alpha}/NF-{kappa}B AND ERK1/2 PATHWAYS AND ADHESION
J. Biol. Chem. 2005 280: 14264-14271. First Published on January 25, 2005; doi:10.1074/jbc.M410791200 [Abstract] [Full Text] [PDF]  

Peter Tormay, Anthony R. M. Coates, and Brian Henderson
The Intercellular Signaling Activity of the Mycobacterium tuberculosis Chaperonin 60.1 Protein Resides in the Equatorial Domain
J. Biol. Chem. 2005 280: 14272-14277. First Published on January 26, 2005; doi:10.1074/jbc.M414158200 [Abstract] [Full Text] [PDF]  

Maximilian Zeyda, Marcus D. Säemann, Karl M. Stuhlmeier, Daniel G. Mascher, Peter N. Nowotny, Gerhard J. Zlabinger, Werner Waldhäusl, and Thomas M. Stulnig
Polyunsaturated Fatty Acids Block Dendritic Cell Activation and Function Independently of NF-{kappa}B Activation
J. Biol. Chem. 2005 280: 14293-14301. First Published on January 31, 2005; doi:10.1074/jbc.M410000200 [Abstract] [Full Text] [PDF]  

Niketa A. Patel, Satoshi Kaneko, Hercules S. Apostolatos, Sun Sik Bae, James E. Watson, Karen Davidowitz, David S. Chappell, Morris J. Birnbaum, Jin Q. Cheng, and Denise R. Cooper
Molecular and Genetic Studies Imply Akt-mediated Signaling Promotes Protein Kinase C{beta}II Alternative Splicing via Phosphorylation of Serine/Arginine-rich Splicing Factor SRp40
J. Biol. Chem. 2005 280: 14302-14309. First Published on January 31, 2005; doi:10.1074/jbc.M411485200 [Abstract] [Full Text] [PDF]  

Yanni Wang and Pauline Johnson
Expression of CD45 Lacking the Catalytic Protein Tyrosine Phosphatase Domain Modulates Lck Phosphorylation and T Cell Activation
J. Biol. Chem. 2005 280: 14318-14324. First Published on February 1, 2005; doi:10.1074/jbc.M413265200 [Abstract] [Full Text] [PDF]  

Asish K. Ghosh, Robert Steele, and Ratna B. Ray
c-myc Promoter-binding Protein 1 (MBP-1) Regulates Prostate Cancer Cell Growth by Inhibiting MAPK Pathway
J. Biol. Chem. 2005 280: 14325-14330. First Published on February 1, 2005; doi:10.1074/jbc.M413313200 [Abstract] [Full Text] [PDF]  

Karen Flatten, Nga T. Dai, Benjamin T. Vroman, David Loegering, Charles Erlichman, Larry M. Karnitz, and Scott H. Kaufmann
The Role of Checkpoint Kinase 1 in Sensitivity to Topoisomerase I Poisons
J. Biol. Chem. 2005 280: 14349-14355. First Published on February 7, 2005; doi:10.1074/jbc.M411890200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:Back

Yoko Sakakida, Yoichi Miyamoto, Emi Nagoshi, Makoto Akashi, Takahiro J. Nakamura, Takayoshi Mamine, Megumi Kasahara, Yasuhiro Minami, Yoshihiro Yoneda, and Toru Takumi
Importin {alpha}/{beta} Mediates Nuclear Transport of a Mammalian Circadian Clock Component, mCRY2, Together with mPER2, through a Bipartite Nuclear Localization Signal
J. Biol. Chem. 2005 280: 13272-13278. First Published on February 2, 2005; doi:10.1074/jbc.M413236200 [Abstract] [Full Text] [PDF]  

Gaetan Pascreau, Jean-Guy Delcros, Jean-Yves Cremet, Claude Prigent, and Yannick Arlot-Bonnemains
Phosphorylation of Maskin by Aurora-A Participates in the Control of Sequential Protein Synthesis during Xenopus laevis Oocyte Maturation
J. Biol. Chem. 2005 280: 13415-13423. First Published on February 1, 2005; doi:10.1074/jbc.M410584200 [Abstract] [Full Text] [PDF]  

Rosalinda Madonna, Pericle Di Napoli, Marika Massaro, Alfredo Grilli, Mario Felaco, Alberto De Caterina, Daming Tang, Raffaele De Caterina, and Yong-Jian Geng
Simvastatin Attenuates Expression of Cytokine-inducible Nitric-oxide Synthase in Embryonic Cardiac Myoblasts
J. Biol. Chem. 2005 280: 13503-13511. First Published on February 10, 2005; doi:10.1074/jbc.M411859200 [Abstract] [Full Text] [PDF]  

Sasha F. Levy, Adria C. LeBoeuf, Michelle R. Massie, Mary Ann Jordan, Leslie Wilson, and Stuart C. Feinstein
Three- and Four-repeat Tau Regulate the Dynamic Instability of Two Distinct Microtubule Subpopulations in Qualitatively Different Manners: IMPLICATIONS FOR NEURODEGENERATION
J. Biol. Chem. 2005 280: 13520-13528. First Published on January 25, 2005; doi:10.1074/jbc.M413490200 [Abstract] [Full Text] [PDF]  

Xinwang Cao, Xia Ding, Zhen Guo, Rihong Zhou, Fengsong Wang, Fei Long, Fang Wu, Feng Bi, Qichen Wang, Daiming Fan, John G. Forte, Maikun Teng, and Xuebiao Yao
PALS1 Specifies the Localization of Ezrin to the Apical Membrane of Gastric Parietal Cells
J. Biol. Chem. 2005 280: 13584-13592. First Published on January 27, 2005; doi:10.1074/jbc.M411941200 [Abstract] [Full Text] [PDF]  

Jun-ichi Hanai, Tadanori Mammoto, Pankaj Seth, Kiyoshi Mori, S. Ananth Karumanchi, Jonathan Barasch, and Vikas P. Sukhatme
Lipocalin 2 Diminishes Invasiveness and Metastasis of Ras-transformed Cells
J. Biol. Chem. 2005 280: 13641-13647. First Published on February 3, 2005; doi:10.1074/jbc.M413047200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Huajing Wan, Sharon Dingle, Yan Xu, Valérie Besnard, Klaus H. Kaestner, Siew-Lan Ang, Susan Wert, Mildred T. Stahlman, and Jeffrey A. Whitsett
Compensatory Roles of Foxa1 and Foxa2 during Lung Morphogenesis
J. Biol. Chem. 2005 280: 13809-13816. First Published on January 24, 2005; doi:10.1074/jbc.M414122200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Jun Xie and Qing Guo
PAR-4 Is Involved in Regulation of {beta}-Secretase Cleavage of the Alzheimer Amyloid Precursor Protein
J. Biol. Chem. 2005 280: 13824-13832. First Published on January 25, 2005; doi:10.1074/jbc.M411933200 [Abstract] [Full Text] [PDF]  

Malini Mansharamani and Katherine L. Wilson
Direct Binding of Nuclear Membrane Protein MAN1 to Emerin in Vitro and Two Modes of Binding to Barrier-to-Autointegration Factor
J. Biol. Chem. 2005 280: 13863-13870. First Published on January 29, 2005; doi:10.1074/jbc.M413020200 [Abstract] [Full Text] [PDF]  

Takaya Ichimura, Sugiko Watanabe, Yasuo Sakamoto, Takahiro Aoto, Naoyuki Fujita, and Mitsuyoshi Nakao
Transcriptional Repression and Heterochromatin Formation by MBD1 and MCAF/AM Family Proteins
J. Biol. Chem. 2005 280: 13928-13935. First Published on February 2, 2005; doi:10.1074/jbc.M413654200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

C. Paul Barrett and Martin E. M. Noble
Molecular Motions of Human Cyclin-dependent Kinase 2
J. Biol. Chem. 2005 280: 13993-14005. First Published on January 28, 2005; doi:10.1074/jbc.M407371200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Makoto Murakami, Seiko Masuda, Kaori Ueda-Semmyo, Emiko Yoda, Hiroshi Kuwata, Yasukazu Takanezawa, Junken Aoki, Hiroyuki Arai, Hideki Sumimoto, Yukio Ishikawa, Toshiharu Ishii, Yoshihito Nakatani, and Ichiro Kudo
Group VIB Ca2+-independent Phospholipase A2{gamma} Promotes Cellular Membrane Hydrolysis and Prostaglandin Production in a Manner Distinct from Other Intracellular Phospholipases A2
J. Biol. Chem. 2005 280: 14028-14041. First Published on February 4, 2005; doi:10.1074/jbc.M413766200 [Abstract] [Full Text] [PDF]  

Masahiro Inoue, Yasuo Nakamura, Kouichi Yasuda, Natsumi Yasaka, Tatsuru Hara, Achim Schnaufer, Kenneth Stuart, and Toshihide Fukuma
The 14-3-3 Proteins of Trypanosoma brucei Function in Motility, Cytokinesis, and Cell Cycle
J. Biol. Chem. 2005 280: 14085-14096. First Published on January 14, 2005; doi:10.1074/jbc.M412336200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Takehito Tsuji and Tetsuo Kunieda
A Loss-of-Function Mutation in Natriuretic Peptide Receptor 2 (Npr2) Gene Is Responsible for Disproportionate Dwarfism in cn/cn Mouse
J. Biol. Chem. 2005 280: 14288-14292. First Published on February 18, 2005; doi:10.1074/jbc.C500024200 [Abstract] [Full Text] [PDF]  


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