JBC Avanti Polar Lipids

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Table of Contents: Jan 14 2005; 280 (2)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption]
      Down Papers Of The Week
      Down Classics
      Down Minireviews
      Down Accelerated Publications
      Down DNA: Replication, Repair, and Recombination
      Down Genes: Structure and Regulation
      Down RNA: Structure, Metabolism, and Catalysis
      Down Protein Synthesis, Post-Translation Modification, and Degradation
      Down Protein Structure and Folding
      Down Enzyme Catalysis and Regulation
      Down Glycobiology and Extracellular Matrices
      Down Lipids and Lipoproteins
      Down Membrane Transport, Structure, Function, and Biogenesis
      Down Mechanisms Of Signal Transduction
      Down Molecular Basis Of Cell and Developmental Biology
      Down Additions and Corrections
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Papers Of The Week:Back

Transporting Sialic Acid
J. Biol. Chem. 2005 280: e99902. [Full Text] [PDF]  


Classics:Back

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
Hans Neurath: the Difference between Proteins That Digest and Proteins That Are Digested
THE SPECIFIC ESTERASE ACTIVITY OF TRYPSIN (George W. Schwert, Hans Neurath, Seymour Kaufman, and John E. Snoke J. Biol. Chem. 172, 221-239)
IDENTIFICATION OF A PEPTIDE RELEASED DURING AUTOCATALYTIC ACTIVATION OF TRYPSINOGEN (Earl W. Davie and Hans Neurath J. Biol. Chem. 212, 515-530)
J. Biol. Chem. 2005 280: e1. [Full Text]  


Minireviews:Back

Suzanne Jackowski and Paolo Fagone
CTP:Phosphocholine Cytidylyltransferase: Paving the Way from Gene to Membrane
J. Biol. Chem. 2005 280: 853-856. First Published on November 9, 2004; doi:10.1074/jbc.R400031200 [Full Text] [PDF]  


Accelerated Publications:Back

Shinji Kamada, Ushio Kikkawa, Yoshihide Tsujimoto, and Tony Hunter
Nuclear Translocation of Caspase-3 Is Dependent on Its Proteolytic Activation and Recognition of a Substrate-like Protein(s)
J. Biol. Chem. 2005 280: 857-860. First Published on November 29, 2004; doi:10.1074/jbc.C400538200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Meng-Jau Lin, Lin-Ya Tang, M. Narsa Reddy, and C.-K. James Shen
DNA Methyltransferase Gene dDnmt2 and Longevity of Drosophila
J. Biol. Chem. 2005 280: 861-864. First Published on November 8, 2004; doi:10.1074/jbc.C400477200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:Back

Marzena Wojciechowska, Albino Bacolla, Jacquelynn E. Larson, and Robert D. Wells
The Myotonic Dystrophy Type 1 Triplet Repeat Sequence Induces Gross Deletions and Inversions
J. Biol. Chem. 2005 280: 941-952. First Published on October 15, 2004; doi:10.1074/jbc.M410427200 [Abstract] [Full Text] [PDF]  

Hong Zang, Thomas M. Harris, and F. Peter Guengerich
Kinetics of Nucleotide Incorporation Opposite DNA Bulky Guanine N2 Adducts by Processive Bacteriophage T7 DNA Polymerase (Exonuclease) and HIV-1 Reverse Transcriptase
J. Biol. Chem. 2005 280: 1165-1178. First Published on November 8, 2004; doi:10.1074/jbc.M405996200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Christopher E. Helt, William A. Cliby, Peter C. Keng, Robert A. Bambara, and Michael A. O'Reilly
Ataxia Telangiectasia Mutated (ATM) and ATM and Rad3-related Protein Exhibit Selective Target Specificities in Response to Different Forms of DNA Damage
J. Biol. Chem. 2005 280: 1186-1192. First Published on November 8, 2004; doi:10.1074/jbc.M410873200 [Abstract] [Full Text] [PDF]  

Lori S. Hart, Steven M. Yannone, Christine Naczki, Joseph S. Orlando, Stephen B. Waters, Steven A. Akman, David J. Chen, David Ornelles, and Constantinos Koumenis
The Adenovirus E4orf6 Protein Inhibits DNA Double Strand Break Repair and Radiosensitizes Human Tumor Cells in an E1B-55K-independent Manner
J. Biol. Chem. 2005 280: 1474-1481. First Published on October 26, 2004; doi:10.1074/jbc.M409934200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:Back

Virginie Firlej, Béatrice Bocquet, Xavier Desbiens, Yvan de Launoit, and Anne Chotteau-Lelièvre
Pea3 Transcription Factor Cooperates with USF-1 in Regulation of the Murine bax Transcription without Binding to an Ets-binding Site
J. Biol. Chem. 2005 280: 887-898. First Published on October 5, 2004; doi:10.1074/jbc.M408017200 [Abstract] [Full Text] [PDF]  

Craig D. Kaplan, Michael J. Holland, and Fred Winston
Interaction between Transcription Elongation Factors and mRNA 3'-End Formation at the Saccharomyces cerevisiae GAL10-GAL7 Locus
J. Biol. Chem. 2005 280: 913-922. First Published on November 5, 2004; doi:10.1074/jbc.M411108200 [Abstract] [Full Text] [PDF]  

Lijuan L. Shang and Samuel C. Dudley, Jr.
Tandem Promoters and Developmentally Regulated 5'- and 3'-mRNA Untranslated Regions of the Mouse Scn5a Cardiac Sodium Channel
J. Biol. Chem. 2005 280: 933-940. First Published on October 14, 2004; doi:10.1074/jbc.M409977200 [Abstract] [Full Text] [PDF]  

Aneta Kasza, Amanda O'Donnell, Karen Gascoigne, Leo A. H. Zeef, Andy Hayes, and Andrew D. Sharrocks
The ETS Domain Transcription Factor Elk-1 Regulates the Expression of Its Partner Protein, SRF
J. Biol. Chem. 2005 280: 1149-1155. First Published on November 4, 2004; doi:10.1074/jbc.M411161200 [Abstract] [Full Text] [PDF]  

Alexander A. Gimelbrant, Alexander W. Ensminger, Peimin Qi, Jacob Zucker, and Andrew Chess
Monoallelic Expression and Asynchronous Replication of p120 Catenin in Mouse and Human Cells
J. Biol. Chem. 2005 280: 1354-1359. First Published on November 1, 2004; doi:10.1074/jbc.M411283200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Aarthi Narayanan, Mauricio L. Nogueira, William T. Ruyechan, and Thomas M. Kristie
Combinatorial Transcription of Herpes Simplex Virus and Varicella Zoster Virus Immediate Early Genes Is Strictly Determined by the Cellular Coactivator HCF-1
J. Biol. Chem. 2005 280: 1369-1375. First Published on November 1, 2004; doi:10.1074/jbc.M410178200 [Abstract] [Full Text] [PDF]  

Kaneyoshi Yamamoto, Kiyo Hirao, Taku Oshima, Hirofumi Aiba, Ryutaro Utsumi, and Akira Ishihama
Functional Characterization in Vitro of All Two-component Signal Transduction Systems from Escherichia coli
J. Biol. Chem. 2005 280: 1448-1456. First Published on November 2, 2004; doi:10.1074/jbc.M410104200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Fenghua Yi, Patricia L. Brubaker, and Tianru Jin
TCF-4 Mediates Cell Type-specific Regulation of Proglucagon Gene Expression by {beta}-Catenin and Glycogen Synthase Kinase-3{beta}
J. Biol. Chem. 2005 280: 1457-1464. First Published on November 2, 2004; doi:10.1074/jbc.M411487200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:Back

Tong Shi, Bill Giannakopoulos, G. Michael Iverson, Keith A. Cockerill, Matthew D. Linnik, and Steven A. Krilis
Domain V of {beta}2-Glycoprotein I Binds Factor XI/XIa and Is Cleaved at Lys317-Thr318
J. Biol. Chem. 2005 280: 907-912. First Published on November 2, 2004; doi:10.1074/jbc.M410291200 [Abstract] [Full Text] [PDF]  

Noriko Umeda, Takeo Suzuki, Masashi Yukawa, Yoshikazu Ohya, Heisaburo Shindo, Kimitsuna Watanabe, and Tsutomu Suzuki
Mitochondria-specific RNA-modifying Enzymes Responsible for the Biosynthesis of the Wobble Base in Mitochondrial tRNAs: IMPLICATIONS FOR THE MOLECULAR PATHOGENESIS OF HUMAN MITOCHONDRIAL DISEASES
J. Biol. Chem. 2005 280: 1613-1624. First Published on October 26, 2004; doi:10.1074/jbc.M409306200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:Back

Cinzia Falasca, Noël Perrier, Jean Massoulié, and Suzanne Bon
Determinants of the t Peptide Involved in Folding, Degradation, and Secretion of Acetylcholinesterase
J. Biol. Chem. 2005 280: 878-886. First Published on September 27, 2004; doi:10.1074/jbc.M409201200 [Abstract] [Full Text] [PDF]  

Linda Söderberg, Hiroyoshi Kakuyama, Anna Möller, Akira Ito, Bengt Winblad, Lars O. Tjernberg, and Jan Näslund
Characterization of the Alzheimer's Disease-associated CLAC Protein and Identification of an Amyloid {beta}-Peptide-binding Site
J. Biol. Chem. 2005 280: 1007-1015. First Published on November 1, 2004; doi:10.1074/jbc.M403628200 [Abstract] [Full Text] [PDF]  

Yojiro Kotake, Keiko Nakayama, Noriko Ishida, and Keiichi I. Nakayama
Role of Serine 10 Phosphorylation in p27 Stabilization Revealed by Analysis of p27 Knock-in Mice Harboring a Serine 10 Mutation
J. Biol. Chem. 2005 280: 1095-1102. First Published on November 3, 2004; doi:10.1074/jbc.M406117200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Malin K. Sandberg and Peter Löw
Altered Interaction and Expression of Proteins Involved in Neurosecretion in Scrapie-infected GT1-1 Cells
J. Biol. Chem. 2005 280: 1264-1271. First Published on November 4, 2004; doi:10.1074/jbc.M411439200 [Abstract] [Full Text] [PDF]  

Jun Liu, Ilya Y. Gluzman, Mark E. Drew, and Daniel E. Goldberg
The Role of Plasmodium falciparum Food Vacuole Plasmepsins
J. Biol. Chem. 2005 280: 1432-1437. First Published on October 28, 2004; doi:10.1074/jbc.M409740200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:Back

Maria Luisa Mangoni, José M. Saugar, Maria Dellisanti, Donatella Barra, Maurizio Simmaco, and Luis Rivas
Temporins, Small Antimicrobial Peptides with Leishmanicidal Activity
J. Biol. Chem. 2005 280: 984-990. First Published on October 28, 2004; doi:10.1074/jbc.M410795200 [Abstract] [Full Text] [PDF]  

Maroor K. Jobby and Yogendra Sharma
Calcium-binding Crystallins from Yersinia pestis: CHARACTERIZATION OF TWO SINGLE {beta}{gamma}-CRYSTALLIN DOMAINS OF A PUTATIVE EXPORTED PROTEIN
J. Biol. Chem. 2005 280: 1209-1216. First Published on November 9, 2004; doi:10.1074/jbc.M409253200 [Abstract] [Full Text] [PDF]  

Hal A. Lewis, Xun Zhao, Chi Wang, J. Michael Sauder, Isabelle Rooney, Brian W. Noland, Don Lorimer, Margaret C. Kearins, Kris Conners, Brad Condon, Peter C. Maloney, William B. Guggino, John F. Hunt, and Spencer Emtage
Impact of the {Delta}F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure
J. Biol. Chem. 2005 280: 1346-1353. First Published on November 3, 2004; doi:10.1074/jbc.M410968200 [Abstract] [Full Text] [PDF]  

Marcel van Lith, Nichola Hartigan, Jennifer Hatch, and Adam M. Benham
PDILT, a Divergent Testis-specific Protein Disulfide Isomerase with a Non-classical SXXC Motif That Engages in Disulfide-dependent Interactions in the Endoplasmic Reticulum
J. Biol. Chem. 2005 280: 1376-1383. First Published on October 8, 2004; doi:10.1074/jbc.M408651200 [Abstract] [Full Text] [PDF]  

Masaaki Katsuki, Victor Tuan Giam Chuang, Koji Nishi, Kohichi Kawahara, Hitoshi Nakayama, Noriyuki Yamaotsu, Shuichi Hirono, and Masaki Otagiri
Use of Photoaffinity Labeling and Site-directed Mutagenesis for Identification of the Key Residue Responsible for Extraordinarily High Affinity Binding of UCN-01 in Human {alpha}1-Acid Glycoprotein
J. Biol. Chem. 2005 280: 1384-1391. First Published on October 27, 2004; doi:10.1074/jbc.M411076200 [Abstract] [Full Text] [PDF]  

J. Carlos Amor, Jennifer Swails, Xinjun Zhu, Craig R. Roy, Hiroki Nagai, Alyssa Ingmundson, Xiaodong Cheng, and Richard A. Kahn
The Structure of RalF, an ADP-ribosylation Factor Guanine Nucleotide Exchange Factor from Legionella pneumophila, Reveals the Presence of a Cap over the Active Site
J. Biol. Chem. 2005 280: 1392-1400. First Published on November 1, 2004; doi:10.1074/jbc.M410820200 [Abstract] [Full Text] [PDF]  

Shahram Misaghi, Paul J. Galardy, Wim J. N. Meester, Huib Ovaa, Hidde L. Ploegh, and Rachelle Gaudet
Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
J. Biol. Chem. 2005 280: 1512-1520. First Published on November 5, 2004; doi:10.1074/jbc.M410770200 [Abstract] [Full Text] [PDF]  

Vivian Pogenberg, Jean-François Guichou, Valérie Vivat-Hannah, Sabrina Kammerer, Efrén Pérez, Pierre Germain, Angel R. de Lera, Hinrich Gronemeyer, Catherine A. Royer, and William Bourguet
Characterization of the Interaction between Retinoic Acid Receptor/Retinoid X Receptor (RAR/RXR) Heterodimers and Transcriptional Coactivators through Structural and Fluorescence Anisotropy Studies
J. Biol. Chem. 2005 280: 1625-1633. First Published on November 4, 2004; doi:10.1074/jbc.M409302200 [Abstract] [Full Text] [PDF]  

Miquel Vila-Perelló, Andrea Sánchez-Vallet, Francisco García-Olmedo, Antonio Molina, and David Andreu
Structural Dissection of a Highly Knotted Peptide Reveals Minimal Motif with Antimicrobial Activity
J. Biol. Chem. 2005 280: 1661-1668. First Published on October 19, 2004; doi:10.1074/jbc.M410577200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Keith E. Bryan and Peter A. Rubenstein
An Intermediate Form of ADP-F-actin
J. Biol. Chem. 2005 280: 1696-1703. First Published on November 9, 2004; doi:10.1074/jbc.M410180200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:Back

Shin'ya Sawada, Hirokazu Suzuki, Fumiko Ichimaida, Masa-atsu Yamaguchi, Takashi Iwashita, Yuko Fukui, Hisashi Hemmi, Tokuzo Nishino, and Toru Nakayama
UDP-glucuronic Acid:Anthocyanin Glucuronosyltransferase from Red Daisy (Bellis perennis) Flowers: ENZYMOLOGY AND PHYLOGENETICS OF A NOVEL GLUCURONOSYLTRANSFERASE INVOLVED IN FLOWER PIGMENT BIOSYNTHESIS
J. Biol. Chem. 2005 280: 899-906. First Published on October 27, 2004; doi:10.1074/jbc.M410537200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Tobias W. B. Ost and Simon Daff
Thermodynamic and Kinetic Analysis of the Nitrosyl, Carbonyl, and Dioxy Heme Complexes of Neuronal Nitric-oxide Synthase: THE ROLES OF SUBSTRATE AND TETRAHYDROBIOPTERIN IN OXYGEN ACTIVATION
J. Biol. Chem. 2005 280: 965-973. First Published on October 26, 2004; doi:10.1074/jbc.M411191200 [Abstract] [Full Text] [PDF]  

Keiko Kubota, Wataru Nishii, Masaki Kojima, and Kenji Takahashi
Specific Inhibition and Stabilization of Aspergilloglutamic Peptidase by the Propeptide: IDENTIFICATION OF CRITICAL SEQUENCES AND RESIDUES IN THE PROPEPTIDE
J. Biol. Chem. 2005 280: 999-1006. First Published on October 30, 2004; doi:10.1074/jbc.M410852200 [Abstract] [Full Text] [PDF]  

Helen M. McGoldrick, Charles A. Roessner, Evelyne Raux, Andrew D. Lawrence, Kirsty J. McLean, Andrew W. Munro, Stefano Santabarbara, Stephen E. J. Rigby, Peter Heathcote, A. Ian Scott, and Martin J. Warren
Identification and Characterization of a Novel Vitamin B12 (Cobalamin) Biosynthetic Enzyme (CobZ) from Rhodobacter capsulatus, Containing Flavin, Heme, and Fe-S Cofactors
J. Biol. Chem. 2005 280: 1086-1094. First Published on November 3, 2004; doi:10.1074/jbc.M411884200 [Abstract] [Full Text] [PDF]  

Päivi Tiainen, Johanna Myllyharju, and Peppi Koivunen
Characterization of a Second Arabidopsis thaliana Prolyl 4-Hydroxylase with Distinct Substrate Specificity
J. Biol. Chem. 2005 280: 1142-1148. First Published on November 4, 2004; doi:10.1074/jbc.M411109200 [Abstract] [Full Text] [PDF]  

Sandrine Gulberti, Virginie Lattard, Magali Fondeur, Jean-Claude Jacquinet, Guillermo Mulliert, Patrick Netter, Jacques Magdalou, Mohamed Ouzzine, and Sylvie Fournel-Gigleux
Phosphorylation and Sulfation of Oligosaccharide Substrates Critically Influence the Activity of Human {beta}1,4-Galactosyltransferase 7 (GalT-I) and {beta}1,3-Glucuronosyltransferase I (GlcAT-I) Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans
J. Biol. Chem. 2005 280: 1417-1425. First Published on November 1, 2004; doi:10.1074/jbc.M411552200 [Abstract] [Full Text] [PDF]  

Andrey A. Komissarov, Peter A. Andreasen, Julie S. Bødker, Paul J. Declerck, John Y. Anagli, and Joseph D. Shore
Additivity in Effects of Vitronectin and Monoclonal Antibodies against {alpha}-Helix F of Plasminogen Activator Inhibitor-1 on Its Reactions with Target Proteinases
J. Biol. Chem. 2005 280: 1482-1489. First Published on October 29, 2004; doi:10.1074/jbc.M408608200 [Abstract] [Full Text] [PDF]  

Srinivas Kodali, Andrew Galgoci, Katherine Young, Ronald Painter, Lynn L. Silver, Kithsiri B. Herath, Sheo B. Singh, Doris Cully, John F. Barrett, Dennis Schmatz, and Jun Wang
Determination of Selectivity and Efficacy of Fatty Acid Synthesis Inhibitors
J. Biol. Chem. 2005 280: 1669-1677. First Published on October 29, 2004; doi:10.1074/jbc.M406848200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Glycobiology and Extracellular Matrices:Back

Abdelmadjid Atrih, Julia M. Richardson, Alan R. Prescott, and Michael A. J. Ferguson
Trypanosoma brucei Glycoproteins Contain Novel Giant Poly-N-acetyllactosamine Carbohydrate Chains
J. Biol. Chem. 2005 280: 865-871. First Published on October 27, 2004; doi:10.1074/jbc.M411061200 [Abstract] [Full Text] [PDF]  

Carol A. Munro, Steven Bates, Ed T. Buurman, H. Bleddyn Hughes, Donna M. MacCallum, Gwyneth Bertram, Abdel Atrih, Michael A. J. Ferguson, Judith M. Bain, Alexandra Brand, Suzanne Hamilton, Caroline Westwater, Lynn M. Thomson, Alistair J. P. Brown, Frank C. Odds, and Neil A. R. Gow
Mnt1p and Mnt2p of Candida albicans Are Partially Redundant {alpha}-1,2-Mannosyltransferases That Participate in O-Linked Mannosylation and Are Required for Adhesion and Virulence
J. Biol. Chem. 2005 280: 1051-1060. First Published on November 1, 2004; doi:10.1074/jbc.M411413200 [Abstract] [Full Text] [PDF]  

Hadar Feinberg, Yuan Guo, Daniel A. Mitchell, Kurt Drickamer, and William I. Weis
Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR
J. Biol. Chem. 2005 280: 1327-1335. First Published on October 26, 2004; doi:10.1074/jbc.M409925200 [Abstract] [Full Text] [PDF]  

Yasuo Yamakoshi, Jan C-C. Hu, Makoto Fukae, Takanori Iwata, Jung-Wook Kim, Hengmin Zhang, and James P. Simmer
Porcine Dentin Sialoprotein Is a Proteoglycan with Glycosaminoglycan Chains Containing Chondroitin 6-Sulfate
J. Biol. Chem. 2005 280: 1552-1560. First Published on November 10, 2004; doi:10.1074/jbc.M409606200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:Back

Maria Stefania Spagnuolo, Luisa Cigliano, Luca D. D'Andrea, Carlo Pedone, and Paolo Abrescia
Assignment of the Binding Site for Haptoglobin on Apolipoprotein A-I
J. Biol. Chem. 2005 280: 1193-1198. First Published on November 8, 2004; doi:10.1074/jbc.M411390200 [Abstract] [Full Text] [PDF]  

Caroline Améen, Ulrika Edvardsson, Anna Ljungberg, Lennart Asp, Peter Åkerblad, Anna Tuneld, Sven-Olof Olofsson, Daniel Lindén, and Jan Oscarsson
Activation of Peroxisome Proliferator-activated Receptor {alpha} Increases the Expression and Activity of Microsomal Triglyceride Transfer Protein in the Liver
J. Biol. Chem. 2005 280: 1224-1229. First Published on November 9, 2004; doi:10.1074/jbc.M412107200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:Back

Carine Robichon, Dominique Vidal-Ingigliardi, and Anthony P. Pugsley
Depletion of Apolipoprotein N-Acyltransferase Causes Mislocalization of Outer Membrane Lipoproteins in Escherichia coli
J. Biol. Chem. 2005 280: 974-983. First Published on October 28, 2004; doi:10.1074/jbc.M411059200 [Abstract] [Full Text] [PDF]  

Takahiro Ueda, Sebastian Brenner, Harry L. Malech, Saskia M. Langemeijer, Shira Perl, Martha Kirby, Oswald A. Phang, Allen E. Krouse, Robert E. Donahue, Elizabeth M. Kang, and John F. Tisdale
Cloning and Functional Analysis of the Rhesus Macaque ABCG2 Gene: FORCED EXPRESSION CONFERS AN SP PHENOTYPE AMONG HEMATOPOIETIC STEM CELL PROGENY IN VIVO
J. Biol. Chem. 2005 280: 991-998. First Published on October 30, 2004; doi:10.1074/jbc.M409796200 [Abstract] [Full Text] [PDF]  

Michela Ottolia, Debora A. Nicoll, and Kenneth D. Philipson
Mutational Analysis of the {alpha}-1 Repeat of the Cardiac Na+-Ca2+ Exchanger
J. Biol. Chem. 2005 280: 1061-1069. First Published on November 1, 2004; doi:10.1074/jbc.M411899200 [Abstract] [Full Text] [PDF]  

Olga Vitavska, Hans Merzendorfer, and Helmut Wieczorek
The V-ATPase Subunit C Binds to Polymeric F-actin as Well as to Monomeric G-actin and Induces Cross-linking of Actin Filaments
J. Biol. Chem. 2005 280: 1070-1076. First Published on November 3, 2004; doi:10.1074/jbc.M406797200 [Abstract] [Full Text] [PDF]  

Christine Salaün, Gwyn W. Gould, and Luke H. Chamberlain
The SNARE Proteins SNAP-25 and SNAP-23 Display Different Affinities for Lipid Rafts in PC12 Cells: REGULATION BY DISTINCT CYSTEINE-RICH DOMAINS
J. Biol. Chem. 2005 280: 1236-1240. First Published on November 12, 2004; doi:10.1074/jbc.M410674200 [Abstract] [Full Text] [PDF]  

Mariko Hara-Chikuma, Baoxue Yang, N. D. Sonawane, Sei Sasaki, Shinichi Uchida, and A. S. Verkman
ClC-3 Chloride Channels Facilitate Endosomal Acidification and Chloride Accumulation
J. Biol. Chem. 2005 280: 1241-1247. First Published on October 25, 2004; doi:10.1074/jbc.M407030200 [Abstract] [Full Text] [PDF]  

Mark E. Williams, Bill Burton, Arturo Urrutia, Anatoly Shcherbatko, Laura E. Chavez-Noriega, Charles J. Cohen, and Jayashree Aiyar
Ric-3 Promotes Functional Expression of the Nicotinic Acetylcholine Receptor {alpha}7 Subunit in Mammalian Cells
J. Biol. Chem. 2005 280: 1257-1263. First Published on October 25, 2004; doi:10.1074/jbc.M410039200 [Abstract] [Full Text] [PDF]  

Werner Kramer, Frank Girbig, Daniel Corsiero, Anja Pfenninger, Wendelin Frick, Gerhard Jähne, Matthias Rhein, Wolfgang Wendler, Friedrich Lottspeich, Elisabeth O. Hochleitner, Evelyn Orsó, and Gerd Schmitz
Aminopeptidase N (CD13) Is a Molecular Target of the Cholesterol Absorption Inhibitor Ezetimibe in the Enterocyte Brush Border Membrane
J. Biol. Chem. 2005 280: 1306-1320. First Published on October 19, 2004; doi:10.1074/jbc.M406309200 [Abstract] [Full Text] [PDF]  

Christopher C. Wreden, Marcin Wlizla, and Richard J. Reimer
Varied Mechanisms Underlie the Free Sialic Acid Storage Disorders
J. Biol. Chem. 2005 280: 1408-1416. First Published on October 29, 2004; doi:10.1074/jbc.M411295200 [Abstract] [Full Text] [PDF] [Summary]  

Simon Scheuring, Johan Busselez, and Daniel Lévy
Structure of the Dimeric PufX-containing Core Complex of Rhodobacter blasticus by in Situ Atomic Force Microscopy
J. Biol. Chem. 2005 280: 1426-1431. First Published on November 1, 2004; doi:10.1074/jbc.M411334200 [Abstract] [Full Text] [PDF]  

James A. Pickett, Peter Thorn, and J. Michael Edwardson
The Plasma Membrane Q-SNARE Syntaxin 2 Enters the Zymogen Granule Membrane during Exocytosis in the Pancreatic Acinar Cell
J. Biol. Chem. 2005 280: 1506-1511. First Published on November 9, 2004; doi:10.1074/jbc.M411967200 [Abstract] [Full Text] [PDF]  

Anna Sedelnikova, Craig D. Smith, Stanislav O. Zakharkin, Delores Davis, David S. Weiss, and Yongchang Chang
Mapping the {rho}1 GABAC Receptor Agonist Binding Pocket: CONSTRUCTING A COMPLETE MODEL
J. Biol. Chem. 2005 280: 1535-1542. First Published on November 17, 2004; doi:10.1074/jbc.M409908200 [Abstract] [Full Text] [PDF]  

Norihiro Nakamura, Shingo Tanaka, Yoshinori Teko, Keiji Mitsui, and Hiroshi Kanazawa
Four Na+/H+ Exchanger Isoforms Are Distributed to Golgi and Post-Golgi Compartments and Are Involved in Organelle pH Regulation
J. Biol. Chem. 2005 280: 1561-1572. First Published on November 2, 2004; doi:10.1074/jbc.M410041200 [Abstract] [Full Text] [PDF]  

Jeffrey Horenstein, Paul Riegelhaupt, and Myles H. Akabas
Differential Protein Mobility of the {gamma}-Aminobutyric Acid, Type A, Receptor {alpha} and {beta} Subunit Channel-lining Segments
J. Biol. Chem. 2005 280: 1573-1581. First Published on November 2, 2004; doi:10.1074/jbc.M410881200 [Abstract] [Full Text] [PDF]  

Anke Reinders, Jody A. Panshyshyn, and John M. Ward
Analysis of Transport Activity of Arabidopsis Sugar Alcohol Permease Homolog AtPLT5
J. Biol. Chem. 2005 280: 1594-1602. First Published on November 3, 2004; doi:10.1074/jbc.M410831200 [Abstract] [Full Text] [PDF]  

Ok-Ho Shin, Weiping Han, Yun Wang, and Thomas C. Südhof
Evolutionarily Conserved Multiple C2 Domain Proteins with Two Transmembrane Regions (MCTPs) and Unusual Ca2+ Binding Properties
J. Biol. Chem. 2005 280: 1641-1651. First Published on November 4, 2004; doi:10.1074/jbc.M407305200 [Abstract] [Full Text] [PDF]  

Sheldon S. Shen, Ward C. Tucker, Edwin R. Chapman, and Richard A. Steinhardt
Molecular Regulation of Membrane Resealing in 3T3 Fibroblasts
J. Biol. Chem. 2005 280: 1652-1660. First Published on November 9, 2004; doi:10.1074/jbc.M410136200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:Back

Xiao-ming Liu, Kelly J. Peyton, Diana Ensenat, Hong Wang, Andrew I. Schafer, Jawed Alam, and William Durante
Endoplasmic Reticulum Stress Stimulates Heme Oxygenase-1 Gene Expression in Vascular Smooth Muscle: ROLE IN CELL SURVIVAL
J. Biol. Chem. 2005 280: 872-877. First Published on November 16, 2004; doi:10.1074/jbc.M410413200 [Abstract] [Full Text] [PDF]  

Akira Yamauchi, Christophe C. Marchal, Jason Molitoris, Nancy Pech, Ulla Knaus, Jason Towe, Simon J. Atkinson, and Mary C. Dinauer
Rac GTPase Isoform-specific Regulation of NADPH Oxidase and Chemotaxis in Murine Neutrophils in Vivo: ROLE OF THE C-TERMINAL POLYBASIC DOMAIN
J. Biol. Chem. 2005 280: 953-964. First Published on October 25, 2004; doi:10.1074/jbc.M408820200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Christopher J. Hupfeld, Jamie L. Resnik, Satoshi Ugi, and Jerrold M. Olefsky
Insulin-induced {beta}-Arrestin1 Ser-412 Phosphorylation Is a Mechanism for Desensitization of ERK Activation by G{alpha}i-coupled Receptors
J. Biol. Chem. 2005 280: 1016-1023. First Published on November 1, 2004; doi:10.1074/jbc.M403674200 [Abstract] [Full Text] [PDF]  

Anil K. Kamaraju and Anita B. Roberts
Role of Rho/ROCK and p38 MAP Kinase Pathways in Transforming Growth Factor-{beta}-mediated Smad-dependent Growth Inhibition of Human Breast Carcinoma Cells in Vivo
J. Biol. Chem. 2005 280: 1024-1036. First Published on November 1, 2004; doi:10.1074/jbc.M403960200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Hitoshi Kusaba, Paritosh Ghosh, Rachel Derin, Meredith Buchholz, Carl Sasaki, Karen Madara, and Dan L. Longo
Interleukin-12-induced Interferon-{gamma} Production by Human Peripheral Blood T Cells Is Regulated by Mammalian Target of Rapamycin (mTOR)
J. Biol. Chem. 2005 280: 1037-1043. First Published on November 1, 2004; doi:10.1074/jbc.M405204200 [Abstract] [Full Text] [PDF]  

Kaleeckal G. Harikumar, Jeremy Clain, Delia I. Pinon, Maoqing Dong, and Laurence J. Miller
Distinct Molecular Mechanisms for Agonist Peptide Binding to Types A and B Cholecystokinin Receptors Demonstrated Using Fluorescence Spectroscopy
J. Biol. Chem. 2005 280: 1044-1050. First Published on November 1, 2004; doi:10.1074/jbc.M409480200 [Abstract] [Full Text] [PDF]  

Jelena Zaric and Curzio Rüegg
Integrin-mediated Adhesion and Soluble Ligand Binding Stabilize COX-2 Protein Levels in Endothelial Cells by Inducing Expression and Preventing Degradation
J. Biol. Chem. 2005 280: 1077-1085. First Published on November 3, 2004; doi:10.1074/jbc.M410006200 [Abstract] [Full Text] [PDF]  

Bin Shan, Ying Zhuo, Dawn Chin, Cindy A. Morris, Gilbert F. Morris, and Joseph A. Lasky
Cyclin-dependent Kinase 9 Is Required for Tumor Necrosis Factor-{alpha}-stimulated Matrix Metalloproteinase-9 Expression in Human Lung Adenocarcinoma Cells
J. Biol. Chem. 2005 280: 1103-1111. First Published on November 4, 2004; doi:10.1074/jbc.M406293200 [Abstract] [Full Text] [PDF]  

Jose P. Vaqué, Joaquin Navascues, Yuzuru Shiio, Marikki Laiho, Nuria Ajenjo, Itsaso Mauleon, David Matallanas, Piero Crespo, and Javier León
Myc Antagonizes Ras-mediated Growth Arrest in Leukemia Cells through the Inhibition of the Ras-ERK-p21Cip1 Pathway
J. Biol. Chem. 2005 280: 1112-1122. First Published on November 4, 2004; doi:10.1074/jbc.M409503200 [Abstract] [Full Text] [PDF]  

Thu Phung-Koskas, Antoine Pilon, Christian Poüs, Cécile Betzina, Marie Sturm, Marie-Lise Bourguet-Kondracki, Geneviève Durand, and Anne Drechou
STAT5B-mediated Growth Hormone Signaling Is Organized by Highly Dynamic Microtubules in Hepatic Cells
J. Biol. Chem. 2005 280: 1123-1131. First Published on November 4, 2004; doi:10.1074/jbc.M409918200 [Abstract] [Full Text] [PDF]  

Elizabeth Keramaris, Jacqueline L. Vanderluit, Mohammad Bahadori, Kambiz Mousavi, Roger J. Davis, Richard Flavell, Ruth S. Slack, and David S. Park
c-Jun N-terminal Kinase 3 Deficiency Protects Neurons from Axotomy-induced Death in Vivo through Mechanisms Independent of c-Jun Phosphorylation
J. Biol. Chem. 2005 280: 1132-1141. First Published on November 4, 2004; doi:10.1074/jbc.M410127200 [Abstract] [Full Text] [PDF]  

Makoto Fujii and John D. York
A Role for Rat Inositol Polyphosphate Kinases rIPK2 and rIPK1 in Inositol Pentakisphosphate and Inositol Hexakisphosphate Production in Rat-1 Cells
J. Biol. Chem. 2005 280: 1156-1164. First Published on November 4, 2004; doi:10.1074/jbc.M412006200 [Abstract] [Full Text] [PDF]  

Takayuki Torigoe, Hiroto Izumi, Tetsuro Wakasugi, Ichiro Niina, Tomonori Igarashi, Takeshi Yoshida, Izumi Shibuya, Kazuo Chijiiwa, Ken-ichi Matsuo, Hideaki Itoh, and Kimitoshi Kohno
DNA Topoisomerase II Poison TAS-103 Transactivates GC-Box-dependent Transcription via Acetylation of Sp1
J. Biol. Chem. 2005 280: 1179-1185. First Published on November 8, 2004; doi:10.1074/jbc.M410499200 [Abstract] [Full Text] [PDF]  

Claire Attwooll, Sergio Oddi, Peter Cartwright, Elena Prosperini, Karl Agger, Peter Steensgaard, Christian Wagener, Claude Sardet, M. Cristina Moroni, and Kristian Helin
A Novel Repressive E2F6 Complex Containing the Polycomb Group Protein, EPC1, That Interacts with EZH2 in a Proliferation-specific Manner
J. Biol. Chem. 2005 280: 1199-1208. First Published on November 8, 2004; doi:10.1074/jbc.M412509200 [Abstract] [Full Text] [PDF]  

Yingqiu Li, Caitlin E. Sedwick, Junru Hu, and Amnon Altman
Role for Protein Kinase C{theta} (PKC{theta}) in TCR/CD28-mediated Signaling through the Canonical but Not the Non-canonical Pathway for NF-{kappa}B Activation
J. Biol. Chem. 2005 280: 1217-1223. First Published on November 9, 2004; doi:10.1074/jbc.M409492200 [Abstract] [Full Text] [PDF]  

Ryan M. Young, Xinmin Zheng, David Holowka, and Barbara Baird
Reconstitution of Regulated Phosphorylation of Fc{epsilon}RI by a Lipid Raft-excluded Protein-tyrosine Phosphatase
J. Biol. Chem. 2005 280: 1230-1235. First Published on November 10, 2004; doi:10.1074/jbc.M408339200 [Abstract] [Full Text] [PDF]  

Angela W. Norton, Suzanne Hosier, Jennifer M. Terew, Ning Li, Anuradha Dhingra, Noga Vardi, Wolfgang Baehr, and Rick H. Cote
Evaluation of the 17-kDa Prenyl-binding Protein as a Regulatory Protein for Phototransduction in Retinal Photoreceptors
J. Biol. Chem. 2005 280: 1248-1256. First Published on October 25, 2004; doi:10.1074/jbc.M410475200 [Abstract] [Full Text] [PDF]  

Beatriz G. Gálvez, Laura Genís, Salomón Matías-Román, Samantha A. Oblander, Karl Tryggvason, Suneel S. Apte, and Alicia G. Arroyo
Membrane Type 1-Matrix Metalloproteinase Is Regulated by Chemokines Monocyte-Chemoattractant Protein-1/CCL2 and Interleukin-8/CXCL8 in Endothelial Cells during Angiogenesis
J. Biol. Chem. 2005 280: 1292-1298. First Published on October 29, 2004; doi:10.1074/jbc.M408673200 [Abstract] [Full Text] [PDF]  

Atsushi Suenaga, Naoki Takada, Mariko Hatakeyama, Mio Ichikawa, Xiaomei Yu, Kentaro Tomii, Noriaki Okimoto, Noriyuki Futatsugi, Tetsu Narumi, Mikako Shirouzu, Shigeyuki Yokoyama, Akihiko Konagaya, and Makoto Taiji
Novel Mechanism of Interaction of p85 Subunit of Phosphatidylinositol 3-Kinase and ErbB3 Receptor-derived Phosphotyrosyl Peptides
J. Biol. Chem. 2005 280: 1321-1326. First Published on November 1, 2004; doi:10.1074/jbc.M410436200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Kee Jun Kim, Jin Woong Chung, and Kwang Sik Kim
67-kDa Laminin Receptor Promotes Internalization of Cytotoxic Necrotizing Factor 1-expressing Escherichia coli K1 into Human Brain Microvascular Endothelial Cells
J. Biol. Chem. 2005 280: 1360-1368. First Published on October 29, 2004; doi:10.1074/jbc.M410176200 [Abstract] [Full Text] [PDF]  

Guangjin Pan and Duanqing Pei
The Stem Cell Pluripotency Factor NANOG Activates Transcription with Two Unusually Potent Subdomains at Its C Terminus
J. Biol. Chem. 2005 280: 1401-1407. First Published on October 22, 2004; doi:10.1074/jbc.M407847200 [Abstract] [Full Text] [PDF]  

Yuanjian Guo, Mario Rebecchi, and Suzanne Scarlata
Phospholipase C{beta}2 Binds to and Inhibits Phospholipase C{delta}1
J. Biol. Chem. 2005 280: 1438-1447. First Published on October 27, 2004; doi:10.1074/jbc.M407593200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Juan Martinez-Pinna, Iman S. Gurung, Catherine Vial, Catherine Leon, Christian Gachet, Richard J. Evans, and Martyn P. Mahaut-Smith
Direct Voltage Control of Signaling via P2Y1 and Other G{alpha}q-coupled Receptors
J. Biol. Chem. 2005 280: 1490-1498. First Published on November 4, 2004; doi:10.1074/jbc.M407783200 [Abstract] [Full Text] [PDF]  

Ralf Gerhard, Helma Tatge, Harald Genth, Thomas Thum, Jürgen Borlak, Gerhard Fritz, and Ingo Just
Clostridium difficile Toxin A Induces Expression of the Stress-induced Early Gene Product RhoB
J. Biol. Chem. 2005 280: 1499-1505. First Published on November 5, 2004; doi:10.1074/jbc.M406014200 [Abstract] [Full Text] [PDF]  

Ryan W. Richman, Jesse Strock, Melinda D. Hains, Nory Jun Cabanilla, King-Kei Lau, David P. Siderovski, and María Diversé-Pierluissi
RGS12 Interacts with the SNARE-binding Region of the Cav2.2 Calcium Channel
J. Biol. Chem. 2005 280: 1521-1528. First Published on November 9, 2004; doi:10.1074/jbc.M406607200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Mathieu Marella, Cédric Gaggioli, Michèle Batoz, Marcel Deckert, Sophie Tartare-Deckert, and Joëlle Chabry
Pathological Prion Protein Exposure Switches on Neuronal Mitogen-activated Protein Kinase Pathway Resulting in Microglia Recruitment
J. Biol. Chem. 2005 280: 1529-1534. First Published on November 4, 2004; doi:10.1074/jbc.M410966200 [Abstract] [Full Text] [PDF]  

Kyung D. Moon, Carol B. Post, Donald L. Durden, Qing Zhou, Pradip De, Marietta L. Harrison, and Robert L. Geahlen
Molecular Basis for a Direct Interaction between the Syk Protein-tyrosine Kinase and Phosphoinositide 3-Kinase
J. Biol. Chem. 2005 280: 1543-1551. First Published on November 9, 2004; doi:10.1074/jbc.M407805200 [Abstract] [Full Text] [PDF]  

Lee W. Slice, Terence Chiu, and Enrique Rozengurt
Angiotensin II and Epidermal Growth Factor Induce Cyclooxygenase-2 Expression in Intestinal Epithelial Cells through Small GTPases Using Distinct Signaling Pathways
J. Biol. Chem. 2005 280: 1582-1593. First Published on November 3, 2004; doi:10.1074/jbc.M408172200 [Abstract] [Full Text] [PDF]  

Robert L. Del Vecchio and Nicholas K. Tonks
The Conserved Immunoglobulin Domain Controls the Subcellular Localization of the Homophilic Adhesion Receptor Protein-tyrosine Phosphatase µ
J. Biol. Chem. 2005 280: 1603-1612. First Published on October 18, 2004; doi:10.1074/jbc.M410181200 [Abstract] [Full Text] [PDF]  

Eiichiro Nagata, Hongbo R. Luo, Adolfo Saiardi, Byoung-Il Bae, Norihiro Suzuki, and Solomon H. Snyder
Inositol Hexakisphosphate Kinase-2, a Physiologic Mediator of Cell Death
J. Biol. Chem. 2005 280: 1634-1640. First Published on November 8, 2004; doi:10.1074/jbc.M409416200 [Abstract] [Full Text] [PDF]  

Harn Shiue, Mark W. Musch, Yingmin Wang, Eugene B. Chang, and Jerrold R. Turner
Akt2 Phosphorylates Ezrin to Trigger NHE3 Translocation and Activation
J. Biol. Chem. 2005 280: 1688-1695. First Published on November 4, 2004; doi:10.1074/jbc.M409471200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:Back

Hui Miao, Klaus Strebhardt, Elena B. Pasquale, Tang-Long Shen, Jun-Lin Guan, and Bingcheng Wang
Inhibition of Integrin-mediated Cell Adhesion but Not Directional Cell Migration Requires Catalytic Activity of EphB3 Receptor Tyrosine Kinase: ROLE OF RHO FAMILY SMALL GTPases
J. Biol. Chem. 2005 280: 923-932. First Published on November 9, 2004; doi:10.1074/jbc.M411383200 [Abstract] [Full Text] [PDF]  

Krystel Louis, Nathalie Guérineau, Olivia Fromigué, Virginie Defamie, Alejandra Collazos, Patrick Anglard, Margaret A. Shipp, Patrick Auberger, Dominique Joubert, and Bernard Mari
Tumor Cell-mediated Induction of the Stromal Factor Stromelysin-3 Requires Heterotypic Cell Contact-dependent Activation of Specific Protein Kinase C Isoforms
J. Biol. Chem. 2005 280: 1272-1283. First Published on October 27, 2004; doi:10.1074/jbc.M405482200 [Abstract] [Full Text] [PDF]  

Rahul S. Rajan and Ron R. Kopito
Suppression of Wild-type Rhodopsin Maturation by Mutants Linked to Autosomal Dominant Retinitis Pigmentosa
J. Biol. Chem. 2005 280: 1284-1291. First Published on October 27, 2004; doi:10.1074/jbc.M406448200 [Abstract] [Full Text] [PDF]  

Nikolaos Giagtzoglou, Konstantinos A. Koumbanakis, John Fullard, Ioanna Zarifi, and Christos Delidakis
Role of the Sc C Terminus in Transcriptional Activation and E(spl) Repressor Recruitment
J. Biol. Chem. 2005 280: 1299-1305. First Published on October 26, 2004; doi:10.1074/jbc.M408949200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Dmitry A. Solovjov, Elzbieta Pluskota, and Edward F. Plow
Distinct Roles for the {alpha} and {beta} Subunits in the Functions of Integrin {alpha}M{beta}2
J. Biol. Chem. 2005 280: 1336-1345. First Published on October 14, 2004; doi:10.1074/jbc.M406968200 [Abstract] [Full Text] [PDF]  

Claire Bertrand, Moussa Benhamed, You-Fang Li, Mira Ayadi, Gaëtan Lemonnier, Jean-Pierre Renou, Marianne Delarue, and Dao-Xiu Zhou
Arabidopsis HAF2 Gene Encoding TATA-binding Protein (TBP)-associated Factor TAF1, Is Required to Integrate Light Signals to Regulate Gene Expression and Growth
J. Biol. Chem. 2005 280: 1465-1473. First Published on November 3, 2004; doi:10.1074/jbc.M409000200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Soh Yamazaki, Tatsushi Muta, Susumu Matsuo, and Koichiro Takeshige
Stimulus-specific Induction of a Novel Nuclear Factor-{kappa}B Regulator, I{kappa}B-{zeta}, via Toll/Interleukin-1 Receptor Is Mediated by mRNA Stabilization
J. Biol. Chem. 2005 280: 1678-1687. First Published on November 2, 2004; doi:10.1074/jbc.M409983200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:Back

Michelle R. Bonello and Levon M. Khachigian
Fibroblast growth factor-2 represses platelet-derived growth factor receptor-{alpha} (PDGFR-{alpha}) transcription via ERK1/2-dependent Sp1 phosphorylation and an atypical cis-acting element in the proximal PDGFR-{alpha} promoter. Vol. 279 (2004) 2377-2382
J. Biol. Chem. 2005 280: 1704. [Full Text] [PDF]  

Yuan Gao, Jinchuan Xing, Michel Streuli, Thomas L. Leto, and Yi Zheng
Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors. Vol. 276 (2001) 47530-47541
J. Biol. Chem. 2005 280: 1704-a. [Full Text] [PDF]  


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