JBC -- Table of Contents (Jun 17 2005, 280, (24))

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Reflections:

Boris Magasanik: Origins
J. Biol. Chem. 2005 280: 22557-22559. First Published on April 19, 2005; doi:10.1074/jbc.X500003200 [Full Text] [PDF]

Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Chargaff's Rules: the Work of Erwin Chargaff
THE SEPARATION AND QUANTITATIVE ESTIMATION OF PURINES AND PYRIMIDINES IN MINUTE AMOUNTS (Ernst Vischer and Erwin Chargaff J. Biol. Chem. 176, 703-714)
J. Biol. Chem. 2005 280: e21. [Full Text]

Accelerated Publications:

Po-Chi Lin, Andrea Puhar, Karin Türk, Stergios Piligkos, Eckhard Bill, Frank Neese, and Julia Steuber: A Vertebrate-type Ferredoxin Domain in the Na⁺-translocating NADH Dehydrogenase from Vibrio cholerae
J. Biol. Chem. 2005 280: 22560-22563. First Published on May 3, 2005; doi:10.1074/jbc.C500171200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Sathees C. Raghavan, Paul Chastain, Jeremy S. Lee, Balachandra G. Hegde, Sabrina Houston, Ralf Langen, Chih-Lin Hsieh, Ian S. Haworth, and Michael R. Lieber: Evidence for a Triplex DNA Conformation at the bcl-2 Major Breakpoint Region of the t(14;18) Translocation
J. Biol. Chem. 2005 280: 22749-22760. First Published on April 18, 2005; doi:10.1074/jbc.M502952200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Amrita Machwe, Liren Xiao, Joanna Groden, Steven W. Matson, and David K. Orren: RecQ Family Members Combine Strand Pairing and Unwinding Activities to Catalyze Strand Exchange
J. Biol. Chem. 2005 280: 23397-23407. First Published on April 20, 2005; doi:10.1074/jbc.M414130200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Xiao Feng Lu, Xiao Gang Jiang, Yun Biao Lu, Jun Hai Bai, and Ze Bin Mao: Characterization of a Novel Positive Transcription Regulatory Element That Differentially Regulates the Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) Gene in Senescent Cells
J. Biol. Chem. 2005 280: 22606-22615. First Published on April 6, 2005; doi:10.1074/jbc.M412073200 [Abstract] [Full Text] [PDF]

Daniel Garneau, Timothée Revil, Jean-François Fisette, and Benoit Chabot: Heterogeneous Nuclear Ribonucleoprotein F/H Proteins Modulate the Alternative Splicing of the Apoptotic Mediator Bcl-x
J. Biol. Chem. 2005 280: 22641-22650. First Published on April 18, 2005; doi:10.1074/jbc.M501070200 [Abstract] [Full Text] [PDF]

Konstantinos G. Drosopoulos, Michael L. Roberts, Lukas Cermak, Takehiko Sasazuki, Senji Shirasawa, Ladislav Andera, and Alexander Pintzas: Transformation by Oncogenic RAS Sensitizes Human Colon Cells to TRAIL-induced Apoptosis by Up-regulating Death Receptor 4 and Death Receptor 5 through a MEK-dependent Pathway
J. Biol. Chem. 2005 280: 22856-22867. First Published on March 8, 2005; doi:10.1074/jbc.M412483200 [Abstract] [Full Text] [PDF]

Kenji Tatematsu, Nobuo Yoshimoto, Tomoyoshi Koyanagi, Chiharu Tokunaga, Taro Tachibana, Yoshihiro Yoneda, Minoru Yoshida, Toshihide Okajima, Katsuyuki Tanizawa, and Shun'ichi Kuroda: Nuclear-Cytoplasmic Shuttling of a RING-IBR Protein RBCK1 and Its Functional Interaction with Nuclear Body Proteins
J. Biol. Chem. 2005 280: 22937-22944. First Published on April 15, 2005; doi:10.1074/jbc.M413476200 [Abstract] [Full Text] [PDF]

Xue-Ji Han, Jei-Keon Chae, Mi-Jin Lee, Kyung-Ran You, Byung-Ho Lee, and Dae-Ghon Kim: Involvement of GADD153 and Cardiac Ankyrin Repeat Protein in Hypoxia-induced Apoptosis of H9c2 Cells
J. Biol. Chem. 2005 280: 23122-23129. First Published on April 12, 2005; doi:10.1074/jbc.M501095200 [Abstract] [Full Text] [PDF]

Kaori Kubota, Daniel H. Lee, Masahiro Tsuchiya, Conan S. Young, Eric T. Everett, Esperanza A. Martinez-Mier, Malcolm L. Snead, Linh Nguyen, Fumihiko Urano, and John D. Bartlett: Fluoride Induces Endoplasmic Reticulum Stress in Ameloblasts Responsible for Dental Enamel Formation
J. Biol. Chem. 2005 280: 23194-23202. First Published on April 23, 2005; doi:10.1074/jbc.M503288200 [Abstract] [Full Text] [PDF]

Tanya C. McCarthy, Xiufeng Li, and Christopher J. Sinal: Vitamin D Receptor-dependent Regulation of Colon Multidrug Resistance-associated Protein 3 Gene Expression by Bile Acids
J. Biol. Chem. 2005 280: 23232-23242. First Published on April 11, 2005; doi:10.1074/jbc.M411520200 [Abstract] [Full Text] [PDF]

Young-Koo Jee, Jane Gilmour, Audrey Kelly, Holly Bowen, David Richards, Cecilia Soh, Philip Smith, Catherine Hawrylowicz, David Cousins, Tak Lee, and Paul Lavender: Repression of Interleukin-5 Transcription by the Glucocorticoid Receptor Targets GATA3 Signaling and Involves Histone Deacetylase Recruitment
J. Biol. Chem. 2005 280: 23243-23250. First Published on April 11, 2005; doi:10.1074/jbc.M503659200 [Abstract] [Full Text] [PDF]

Jin Wang, Hui Liu, Chi Mei Lin, Mirit I. Aladjem, and Elliot M. Epner: Targeted Deletion of the Chicken ${beta}$ -Globin Regulatory Elements Reveals a Cooperative Gene Silencing Activity
J. Biol. Chem. 2005 280: 23340-23348. First Published on April 11, 2005; doi:10.1074/jbc.M501161200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Mark J. Howard and C. Mark Smales: NMR Analysis of Synthetic Human Serum Albumin ${alpha}$ -Helix 28 Identifies Structural Distortion upon Amadori Modification
J. Biol. Chem. 2005 280: 22582-22589. First Published on April 18, 2005; doi:10.1074/jbc.M501480200 [Abstract] [Full Text] [PDF]

Chang-Wei Liu, Benoit I. Giasson, Karen A. Lewis, Virginia M. Lee, George N. DeMartino, and Philip J. Thomas: A Precipitating Role for Truncated ${alpha}$ -Synuclein and the Proteasome in ${alpha}$ -Synuclein Aggregation: IMPLICATIONS FOR PATHOGENESIS OF PARKINSON DISEASE
J. Biol. Chem. 2005 280: 22670-22678. First Published on April 19, 2005; doi:10.1074/jbc.M501508200 [Abstract] [Full Text] [PDF]

Subramaniam Pennathur, Yasuo Ido, Jozsef I. Heller, Jaeman Byun, Ratna Danda, Pablo Pergola, Joseph R. Williamson, and Jay W. Heinecke: Reactive Carbonyls and Polyunsaturated Fatty Acids Produce a Hydroxyl Radical-like Species: A POTENTIAL PATHWAY FOR OXIDATIVE DAMAGE OF RETINAL PROTEINS IN DIABETES
J. Biol. Chem. 2005 280: 22706-22714. First Published on April 25, 2005; doi:10.1074/jbc.M500839200 [Abstract] [Full Text] [PDF]

Nancy Skacel, Lata G. Menon, Prasunkumar J. Mishra, Rowayda Peters, Debabrata Banerjee, Joseph R. Bertino, and Emine Ercikan Abali: Identification of Amino Acids Required for the Functional Up-regulation of Human Dihydrofolate Reductase Protein in Response to Antifolate Treatment
J. Biol. Chem. 2005 280: 22721-22731. First Published on April 6, 2005; doi:10.1074/jbc.M500277200 [Abstract] [Full Text] [PDF]

Eunyong Park, Young Min Rho, Ohn-jo Koh, Sung Won Ahn, Ihn Sik Seong, Ji-Joon Song, Oksun Bang, Jae Hong Seol, Jimin Wang, Soo Hyun Eom, and Chin Ha Chung: Role of the GYVG Pore Motif of HslU ATPase in Protein Unfolding and Translocation for Degradation by HslV Peptidase
J. Biol. Chem. 2005 280: 22892-22898. First Published on April 22, 2005; doi:10.1074/jbc.M500035200 [Abstract] [Full Text] [PDF]

Manasi Chavan, Aixin Yan, and William J. Lennarz: Subunits of the Translocon Interact with Components of the Oligosaccharyl Transferase Complex
J. Biol. Chem. 2005 280: 22917-22924. First Published on April 14, 2005; doi:10.1074/jbc.M502858200 [Abstract] [Full Text] [PDF]

Hon-Kit Wong, Takashi Sakurai, Fumitaka Oyama, Kumi Kaneko, Koji Wada, Haruko Miyazaki, Masaru Kurosawa, Bart De Strooper, Paul Saftig, and Nobuyuki Nukina: ${beta}$ Subunits of Voltage-gated Sodium Channels Are Novel Substrates of ${beta}$ -Site Amyloid Precursor Protein-cleaving Enzyme (BACE1) and ${gamma}$ -Secretase
J. Biol. Chem. 2005 280: 23009-23017. First Published on April 11, 2005; doi:10.1074/jbc.M414648200 [Abstract] [Full Text] [PDF]

Doo Yeon Kim, Laura A. MacKenzie Ingano, Bryce W. Carey, Warren H. Pettingell, and Dora M. Kovacs: Presenilin/ ${gamma}$ -Secretase-mediated Cleavage of the Voltage-gated Sodium Channel ${beta}$ 2-Subunit Regulates Cell Adhesion and Migration
J. Biol. Chem. 2005 280: 23251-23261. First Published on April 14, 2005; doi:10.1074/jbc.M412938200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Laura Caldinelli, Stefania Iametti, Alberto Barbiroli, Francesco Bonomi, Dimitrios Fessas, Gianluca Molla, Mirella S. Pilone, and Loredano Pollegioni: Dissecting the Structural Determinants of the Stability of Cholesterol Oxidase Containing Covalently Bound Flavin
J. Biol. Chem. 2005 280: 22572-22581. First Published on April 7, 2005; doi:10.1074/jbc.M500549200 [Abstract] [Full Text] [PDF]

Yuan-yuan Shi, Xin-guo Hong, and Chih-chen Wang: The C-terminal (331–376) Sequence of Escherichia coli DnaJ Is Essential for Dimerization and Chaperone Activity: A SMALL ANGLE X-RAY SCATTERING STUDY IN SOLUTION
J. Biol. Chem. 2005 280: 22761-22768. First Published on April 21, 2005; doi:10.1074/jbc.M503643200 [Abstract] [Full Text] [PDF]

Per Eugen Kristiansen, Gunnar Fimland, Dimitris Mantzilas, and Jon Nissen-Meyer: Structure and Mode of Action of the Membrane-permeabilizing Antimicrobial Peptide Pheromone Plantaricin A
J. Biol. Chem. 2005 280: 22945-22950. First Published on April 1, 2005; doi:10.1074/jbc.M501620200 [Abstract] [Full Text] [PDF]

Tetsuya Ishino, Cecilia Urbina, Madhushree Bhattacharya, Dominick Panarello, and Irwin Chaiken: Receptor Epitope Usage by an Interleukin-5 Mimetic Peptide
J. Biol. Chem. 2005 280: 22951-22961. First Published on April 12, 2005; doi:10.1074/jbc.M502341200 [Abstract] [Full Text] [PDF]

Deqiang Wang, Min Guo, Zhi Liang, Jun Fan, Zhiqiang Zhu, Jianye Zang, Zhongliang Zhu, Xiaowu Li, Maikun Teng, Liwen Niu, Yuhui Dong, and Peng Liu: Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-like Fold and Two Protein-Protein Interaction Sites
J. Biol. Chem. 2005 280: 22962-22967. First Published on March 23, 2005; doi:10.1074/jbc.M500464200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Madhulika Jain, Michael S. Evans, Jonathan King, and Patricia L. Clark: Monoclonal Antibody Epitope Mapping Describes Tailspike ${beta}$ -Helix Folding and Aggregation Intermediates
J. Biol. Chem. 2005 280: 23032-23040. First Published on April 14, 2005; doi:10.1074/jbc.M501963200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zhi-Song Qiao, Mikyung Kim, Bruce Reinhold, David Montefiori, Jia-huai Wang, and Ellis L. Reinherz: Design, Expression, and Immunogenicity of a Soluble HIV Trimeric Envelope Fragment Adopting a Prefusion gp41 Configuration
J. Biol. Chem. 2005 280: 23138-23146. First Published on April 15, 2005; doi:10.1074/jbc.M414515200 [Abstract] [Full Text] [PDF]

Sau-Ching Wu and Sui-Lam Wong: Engineering Soluble Monomeric Streptavidin with Reversible Biotin Binding Capability
J. Biol. Chem. 2005 280: 23225-23231. First Published on April 19, 2005; doi:10.1074/jbc.M501733200 [Abstract] [Full Text] [PDF] [Supplemental Data]

I-Mei Yu, Christin L. T. Gustafson, Jianbo Diao, John W. Burgner, II, Zhihong Li, Jingqiang Zhang, and Jue Chen: Recombinant Severe Acute Respiratory Syndrome (SARS) Coronavirus Nucleocapsid Protein Forms a Dimer through Its C-terminal Domain
J. Biol. Chem. 2005 280: 23280-23286. First Published on April 21, 2005; doi:10.1074/jbc.M501015200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Claudio F. Gonzalez, David F. Ackerley, Susan V. Lynch, and A. Matin: ChrR, a Soluble Quinone Reductase of Pseudomonas putida That Defends against H₂O₂
J. Biol. Chem. 2005 280: 22590-22595. First Published on April 19, 2005; doi:10.1074/jbc.M501654200 [Abstract] [Full Text] [PDF]

Reza A. Ghiladi, Giselle M. Knudsen, Katalin F. Medzihradszky, and Paul R. Ortiz de Montellano: The Met-Tyr-Trp Cross-link in Mycobacterium tuberculosis Catalase-peroxidase (KatG): AUTOCATALYTIC FORMATION AND EFFECT ON ENZYME CATALYSIS AND SPECTROSCOPIC PROPERTIES
J. Biol. Chem. 2005 280: 22651-22663. First Published on April 18, 2005; doi:10.1074/jbc.M502486200 [Abstract] [Full Text] [PDF]

Xiang He, Max J. Cryle, James J. Ortiz De Voss, and Paul R. de Montellano: Calibration of the Channel That Determines the ${omega}$ -Hydroxylation Regiospecificity of Cytochrome P4504A1: CATALYTIC OXIDATION OF 12-HALODODECANOIC ACIDS
J. Biol. Chem. 2005 280: 22697-22705. First Published on April 22, 2005; doi:10.1074/jbc.M502632200 [Abstract] [Full Text] [PDF]

Wen-Chi Hsu, Hui-Chuan Chang, Chi-Yuan Chou, Pui-Jen Tsai, Pei-In Lin, and Gu-Gang Chang: Critical Assessment of Important Regions in the Subunit Association and Catalytic Action of the Severe Acute Respiratory Syndrome Coronavirus Main Protease
J. Biol. Chem. 2005 280: 22741-22748. First Published on April 14, 2005; doi:10.1074/jbc.M502556200 [Abstract] [Full Text] [PDF]

Kye-Young Kim, Mihály Kovács, Sachiyo Kawamoto, James R. Sellers, and Robert S. Adelstein: Disease-associated Mutations and Alternative Splicing Alter the Enzymatic and Motile Activity of Nonmuscle Myosins II-B and II-C
J. Biol. Chem. 2005 280: 22769-22775. First Published on April 20, 2005; doi:10.1074/jbc.M503488200 [Abstract] [Full Text] [PDF]

Gareth J. Williams, Steven D. Breazeale, Christian R. H. Raetz, and James H. Naismith: Structure and Function of Both Domains of ArnA, a Dual Function Decarboxylase and a Formyltransferase, Involved in 4-Amino-4-deoxy-L-arabinose Biosynthesis
J. Biol. Chem. 2005 280: 23000-23008. First Published on April 4, 2005; doi:10.1074/jbc.M501534200 [Abstract] [Full Text] [PDF]

Jirí Lísal and Roman Tuma: Cooperative Mechanism of RNA Packaging Motor
J. Biol. Chem. 2005 280: 23157-23164. First Published on April 18, 2005; doi:10.1074/jbc.M502658200 [Abstract] [Full Text] [PDF]

Thomas Linke, Harry Dawson, and Earl H. Harrison: Isolation and Characterization of a Microsomal Acid Retinyl Ester Hydrolase
J. Biol. Chem. 2005 280: 23287-23294. First Published on March 14, 2005; doi:10.1074/jbc.M413585200 [Abstract] [Full Text] [PDF]

Raimondo De Cristofaro, Flora Peyvandi, Roberta Palla, Silvia Lavoretano, Rossana Lombardi, Giuliana Merati, Federica Romitelli, Enrico Di Stasio, and Pier Mannuccio Mannucci: Role of Chloride Ions in Modulation of the Interaction between von Willebrand Factor and ADAMTS-13
J. Biol. Chem. 2005 280: 23295-23302. First Published on April 4, 2005; doi:10.1074/jbc.M501143200 [Abstract] [Full Text] [PDF]

Noriko Ueno, Ryu Takeya, Kei Miyano, Hideaki Kikuchi, and Hideki Sumimoto: The NADPH Oxidase Nox3 Constitutively Produces Superoxide in a p22^phox-dependent Manner: ITS REGULATION BY OXIDASE ORGANIZERS AND ACTIVATORS
J. Biol. Chem. 2005 280: 23328-23339. First Published on April 11, 2005; doi:10.1074/jbc.M414548200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Rajesh T. Patel, Jose L. Soulages, Balaji Hariharasundaram, and Estela L. Arrese: Activation of the Lipid Droplet Controls the Rate of Lipolysis of Triglycerides in the Insect Fat Body
J. Biol. Chem. 2005 280: 22624-22631. First Published on April 13, 2005; doi:10.1074/jbc.M413128200 [Abstract] [Full Text] [PDF]

Edward Luk, Mei Yang, Laran T. Jensen, Yves Bourbonnais, and Valeria Cizewski Culotta: Manganese Activation of Superoxide Dismutase 2 in the Mitochondria of Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 22715-22720. First Published on April 25, 2005; doi:10.1074/jbc.M504257200 [Abstract] [Full Text] [PDF]

Raul Covian and Bernard L. Trumpower: Rapid Electron Transfer between Monomers when the Cytochrome bc₁ Complex Dimer Is Reduced through Center N
J. Biol. Chem. 2005 280: 22732-22740. First Published on April 15, 2005; doi:10.1074/jbc.M413592200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Andy Y. Shih, Sophie Imbeault, Vilte Barakauskas, Heidi Erb, Lei Jiang, Ping Li, and Timothy H. Murphy: Induction of the Nrf2-driven Antioxidant Response Confers Neuroprotection during Mitochondrial Stress in Vivo
J. Biol. Chem. 2005 280: 22925-22936. First Published on April 19, 2005; doi:10.1074/jbc.M414635200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Clara Prats, Joan A. Cadefau, Roser Cussó, Klaus Qvortrup, Jakob N. Nielsen, Jørgen F. P. Wojtaszewki, D. Grahame Hardie, Greg Stewart, Bo F. Hansen, and Thorkil Ploug: Phosphorylation-dependent Translocation of Glycogen Synthase to a Novel Structure during Glycogen Resynthesis
J. Biol. Chem. 2005 280: 23165-23172. First Published on April 19, 2005; doi:10.1074/jbc.M502713200 [Abstract] [Full Text] [PDF]

David Y. Takeda, Jeffrey D. Parvin, and Anindya Dutta: Degradation of Cdt1 during S Phase Is Skp2-independent and Is Required for Efficient Progression of Mammalian Cells through S Phase
J. Biol. Chem. 2005 280: 23416-23423. First Published on April 25, 2005; doi:10.1074/jbc.M501208200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Vasiliki Petropoulou, Laure Garrigue-Antar, and Karl E. Kadler: Identification of the Minimal Domain Structure of Bone Morphogenetic Protein-1 (BMP-1) for Chordinase Activity: CHORDINASE ACTIVITY IS NOT ENHANCED BY PROCOLLAGEN C-PROTEINASE ENHANCER-1 (PCPE-1)
J. Biol. Chem. 2005 280: 22616-22623. First Published on April 7, 2005; doi:10.1074/jbc.M413468200 [Abstract] [Full Text] [PDF]

Michael D. Urbaniak, Arthur Crossman, Tunhan Chang, Terry K. Smith, Daan M. F. van Aalten, and Michael A. J. Ferguson: The N-Acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of Glycosylphosphatidylinositol Biosynthesis Is a Zinc Metalloenzyme
J. Biol. Chem. 2005 280: 22831-22838. First Published on April 6, 2005; doi:10.1074/jbc.M502402200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Peter J. Coombs, Sarah A. Graham, Kurt Drickamer, and Maureen E. Taylor: Selective Binding of the Scavenger Receptor C-type Lectin to Lewis^x Trisaccharide and Related Glycan Ligands
J. Biol. Chem. 2005 280: 22993-22999. First Published on April 21, 2005; doi:10.1074/jbc.M504197200 [Abstract] [Full Text] [PDF]

Vinay M. Bhide, Carol A. Laschinger, Pamela D. Arora, Wilson Lee, Lari Hakkinen, Hannu Larjava, Jaro Sodek, and Christopher A. McCulloch: Collagen Phagocytosis by Fibroblasts Is Regulated by Decorin
J. Biol. Chem. 2005 280: 23103-23113. First Published on April 4, 2005; doi:10.1074/jbc.M410060200 [Abstract] [Full Text] [PDF]

Xingfeng Bao, Mauro S. G. Pavão, Joana Cabral dos Santos, and Kazuyuki Sugahara: A Functional Dermatan Sulfate Epitope Containing Iduronate(2-O-sulfate) ${alpha}$ 1–3GalNAc(6-O-sulfate) Disaccharide in the Mouse Brain: DEMONSTRATION USING A NOVEL MONOCLONAL ANTIBODY RAISED AGAINST DERMATAN SULFATE OF ASCIDIAN ASCIDIA NIGRA
J. Biol. Chem. 2005 280: 23184-23193. First Published on April 22, 2005; doi:10.1074/jbc.M503036200 [Abstract] [Full Text] [PDF]

Steven Bates, Donna M. MacCallum, Gwyneth Bertram, Carol A. Munro, H. Bleddyn Hughes, Ed T. Buurman, Alistair J. P. Brown, Frank C. Odds, and Neil A. R. Gow: Candida albicans Pmr1p, a Secretory Pathway P-type Ca²⁺/Mn²⁺-ATPase, Is Required for Glycosylation and Virulence
J. Biol. Chem. 2005 280: 23408-23415. First Published on April 20, 2005; doi:10.1074/jbc.M502162200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Hideki Sakagami, Junken Aoki, Yumiko Natori, Kiyotaka Nishikawa, Yoshiyuki Kakehi, Yasuhiro Natori, and Hiroyuki Arai: Biochemical and Molecular Characterization of a Novel Choline-specific Glycerophosphodiester Phosphodiesterase Belonging to the Nucleotide Pyrophosphatase/Phosphodiesterase Family
J. Biol. Chem. 2005 280: 23084-23093. First Published on March 23, 2005; doi:10.1074/jbc.M413438200 [Abstract] [Full Text] [PDF]

Agnieszka Dobrzyn, Pawel Dobrzyn, Makoto Miyazaki, Harini Sampath, Kiki Chu, and James M. Ntambi: Stearoyl-CoA Desaturase 1 Deficiency Increases CTP:Choline Cytidylyltransferase Translocation into the Membrane and Enhances Phosphatidylcholine Synthesis in Liver
J. Biol. Chem. 2005 280: 23356-23362. First Published on April 13, 2005; doi:10.1074/jbc.M502436200 [Abstract] [Full Text] [PDF]

Debin Lan and David L. Silver: Fenofibrate Induces a Novel Degradation Pathway for Scavenger Receptor B-I Independent of PDZK1
J. Biol. Chem. 2005 280: 23390-23396. First Published on April 18, 2005; doi:10.1074/jbc.M502777200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Heather S. Carr, Andrew B. Maxfield, Yih-Chern Horng, and Dennis R. Winge: Functional Analysis of the Domains in Cox11
J. Biol. Chem. 2005 280: 22664-22669. First Published on April 19, 2005; doi:10.1074/jbc.M414077200 [Abstract] [Full Text] [PDF]

Jo Vanoevelen, Leonard Dode, Kurt Van Baelen, Rebecca J. Fairclough, Ludwig Missiaen, Luc Raeymaekers, and Frank Wuytack: The Secretory Pathway Ca²⁺/Mn²⁺-ATPase 2 Is a Golgi-localized Pump with High Affinity for Ca²⁺ Ions
J. Biol. Chem. 2005 280: 22800-22808. First Published on April 14, 2005; doi:10.1074/jbc.M501026200 [Abstract] [Full Text] [PDF]

Daniel Sher, Yelena Fishman, Mingliang Zhang, Mario Lebendiker, Ariel Gaathon, José-Miguel Mancheño, and Eliahu Zlotkin: Hydralysins, a New Category of ${beta}$ -Pore-forming Toxins in Cnidaria
J. Biol. Chem. 2005 280: 22847-22855. First Published on April 11, 2005; doi:10.1074/jbc.M503242200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bernd Nilius, Jean Prenen, Annelies Janssens, Grzegorz Owsianik, Chunbo Wang, Michael X. Zhu, and Thomas Voets: The Selectivity Filter of the Cation Channel TRPM4
J. Biol. Chem. 2005 280: 22899-22906. First Published on April 21, 2005; doi:10.1074/jbc.M501686200 [Abstract] [Full Text] [PDF]

Frédéric Jaskolski, Elisabeth Normand, Christophe Mulle, and Françoise Coussen: Differential Trafficking of GluR7 Kainate Receptor Subunit Splice Variants
J. Biol. Chem. 2005 280: 22968-22976. First Published on April 1, 2005; doi:10.1074/jbc.M413166200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shin-ichiro Yoshimura, Katsuji Yoshioka, Francis A. Barr, Martin Lowe, Kazuhisa Nakayama, Shoji Ohkuma, and Nobuhiro Nakamura: Convergence of Cell Cycle Regulation and Growth Factor Signals on GRASP65
J. Biol. Chem. 2005 280: 23048-23056. First Published on April 15, 2005; doi:10.1074/jbc.M502442200 [Abstract] [Full Text] [PDF]

Guoqiang Zhu, Huaiqing Chen, Byung-Kwon Choi, Fabio Del Piero, and Dieter M. Schifferli: Histone H1 Proteins Act As Receptors for the 987P Fimbriae of Enterotoxigenic Escherichia coli
J. Biol. Chem. 2005 280: 23057-23065. First Published on April 19, 2005; doi:10.1074/jbc.M503676200 [Abstract] [Full Text] [PDF]

Naoko Morinaga, Yoshifumi Iwamaru, Kinnosuke Yahiro, Motoyuki Tagashira, Joel Moss, and Masatoshi Noda: Differential Activities of Plant Polyphenols on the Binding and Internalization of Cholera Toxin in Vero Cells
J. Biol. Chem. 2005 280: 23303-23309. First Published on April 6, 2005; doi:10.1074/jbc.M502093200 [Abstract] [Full Text] [PDF]

Graeme I. Lancaster and Mark A. Febbraio: Exosome-dependent Trafficking of HSP70: A NOVEL SECRETORY PATHWAY FOR CELLULAR STRESS PROTEINS
J. Biol. Chem. 2005 280: 23349-23355. First Published on April 12, 2005; doi:10.1074/jbc.M502017200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Bradley S. Henson, Richard R. Neubig, Ilwhan Jang, Tetsuya Ogawa, Zhaocheng Zhang, Thomas E. Carey, and Nisha J. D'Silva: Galanin Receptor 1 Has Anti-proliferative Effects in Oral Squamous Cell Carcinoma
J. Biol. Chem. 2005 280: 22564-22571. First Published on March 14, 2005; doi:10.1074/jbc.M414589200 [Abstract] [Full Text] [PDF]

Emily K. Thomas, Misa Nakamura, Dirk Wienke, Clare M. Isacke, Ambra Pozzi, and Peng Liang: Endo180 Binds to the C-terminal Region of Type I Collagen
J. Biol. Chem. 2005 280: 22596-22605. First Published on April 6, 2005; doi:10.1074/jbc.M501155200 [Abstract] [Full Text] [PDF]

Lennart Zabeau, Delphine Defeau, Hannes Iserentant, Joël Vandekerckhove, Frank Peelman, and Jan Tavernier: Leptin Receptor Activation Depends on Critical Cysteine Residues in Its Fibronectin Type III Subdomains
J. Biol. Chem. 2005 280: 22632-22640. First Published on April 18, 2005; doi:10.1074/jbc.M413308200 [Abstract] [Full Text] [PDF]

Ke Liu, Xiping Zhang, Robert L. Lester, and Robert C. Dickson: The Sphingoid Long Chain Base Phytosphingosine Activates AGC-type Protein Kinases in Saccharomyces cerevisiae Including Ypk1, Ypk2, and Sch9
J. Biol. Chem. 2005 280: 22679-22687. First Published on April 19, 2005; doi:10.1074/jbc.M502972200 [Abstract] [Full Text] [PDF]

Juan Wang, Hao Feng, Xiao-Qin Huang, Hua Xiang, Ying-Wei Mao, Jin-Ping Liu, Qin Yan, Wen-Bin Liu, Yan Liu, Mi Deng, Lili Gong, Shuming Sun, Chen Luo, Shao-Jun Liu, Xuan-Jie Zhang, Yun Liu, and David Wan-Cheng Li: Human Telomerase Reverse Transcriptase Immortalizes Bovine Lens Epithelial Cells and Suppresses Differentiation through Regulation of the ERK Signaling Pathway
J. Biol. Chem. 2005 280: 22776-22787. First Published on April 22, 2005; doi:10.1074/jbc.M500032200 [Abstract] [Full Text] [PDF]

Runxiang Zhao, Shu Xing, Zhe Li, Xueqi Fu, Qingshan Li, Sanford B. Krantz, and Zhizhuang Joe Zhao: Identification of an Acquired JAK2 Mutation in Polycythemia Vera
J. Biol. Chem. 2005 280: 22788-22792. First Published on April 29, 2005; doi:10.1074/jbc.C500138200 [Abstract] [Full Text] [PDF]

Alexander N. R. Weber, Martin C. Moncrieffe, Monique Gangloff, Jean-Luc Imler, and Nicholas J. Gay: Ligand-Receptor and Receptor-Receptor Interactions Act in Concert to Activate Signaling in the Drosophila Toll Pathway
J. Biol. Chem. 2005 280: 22793-22799. First Published on March 28, 2005; doi:10.1074/jbc.M502074200 [Abstract] [Full Text] [PDF] [Summary]

Tian-yun Wang, Rania Leventis, and John R. Silvius: Artificially Lipid-anchored Proteins Can Elicit Clustering-induced Intracellular Signaling Events in Jurkat T-Lymphocytes Independent of Lipid Raft Association
J. Biol. Chem. 2005 280: 22839-22846. First Published on April 7, 2005; doi:10.1074/jbc.M502920200 [Abstract] [Full Text] [PDF]

Mitsunobu Hoshino, Tamotsu Yoshimori, and Shun Nakamura: Small GTPase Proteins Rin and Rit Bind to PAR6 GTP-dependently and Regulate Cell Transformation
J. Biol. Chem. 2005 280: 22868-22874. First Published on April 14, 2005; doi:10.1074/jbc.M411592200 [Abstract] [Full Text] [PDF]

Osvaldo Rey, Steven H. Young, Jingzhen Yuan, Lee Slice, and Enrique Rozengurt: Amino Acid-stimulated Ca²⁺ Oscillations Produced by the Ca²⁺-sensing Receptor Are Mediated by a Phospholipase C/Inositol 1,4,5-Trisphosphate-independent Pathway That Requires G₁₂, Rho, Filamin-A, and the Actin Cytoskeleton
J. Biol. Chem. 2005 280: 22875-22882. First Published on April 18, 2005; doi:10.1074/jbc.M503455200 [Abstract] [Full Text] [PDF]

Jian-Bin Wang, Wen Jin Wu, and Richard A. Cerione: Cdc42 and Ras Cooperate to Mediate Cellular Transformation by Intersectin-L
J. Biol. Chem. 2005 280: 22883-22891. First Published on April 11, 2005; doi:10.1074/jbc.M414375200 [Abstract] [Full Text] [PDF]

Chih-Hsin Tang, Rong-Sen Yang, and Wen-Mei Fu: Prostaglandin E₂ Stimulates Fibronectin Expression through EP₁ Receptor, Phospholipase C, Protein Kinase C ${alpha}$ , and c-Src Pathway in Primary Cultured Rat Osteoblasts
J. Biol. Chem. 2005 280: 22907-22916. First Published on April 15, 2005; doi:10.1074/jbc.M500130200 [Abstract] [Full Text] [PDF]

M. Nauman Jhandier, Emma A. Kruglov, Élise G. Lavoie, Jean Sévigny, and Jonathan A. Dranoff: Portal Fibroblasts Regulate the Proliferation of Bile Duct Epithelia via Expression of NTPDase2
J. Biol. Chem. 2005 280: 22986-22992. First Published on March 30, 2005; doi:10.1074/jbc.M412371200 [Abstract] [Full Text] [PDF]

Tomomi Fujii, Naoya Onohara, Yoshiko Maruyama, Shihori Tanabe, Hiroyuki Kobayashi, Masashi Fukutomi, Yuichi Nagamatsu, Naoki Nishihara, Ryuji Inoue, Hideki Sumimoto, Futoshi Shibasaki, Taku Nagao, Motohiro Nishida, and Hitoshi Kurose: G ${alpha}$ 12/13-mediated Production of Reactive Oxygen Species Is Critical for Angiotensin Receptor-induced NFAT Activation in Cardiac Fibroblasts
J. Biol. Chem. 2005 280: 23041-23047. First Published on April 12, 2005; doi:10.1074/jbc.M409397200 [Abstract] [Full Text] [PDF] [Supplemental Data]

James D. Swant, Beatriz E. Rendon, Marc Symons, and Robert A. Mitchell: Rho GTPase-dependent Signaling Is Required for Macrophage Migration Inhibitory Factor-mediated Expression of Cyclin D1
J. Biol. Chem. 2005 280: 23066-23072. First Published on April 19, 2005; doi:10.1074/jbc.M500636200 [Abstract] [Full Text] [PDF]

Adriana J. Bernal, Qilin Pan, Jeff Pollack, Laura Rose, Alexander Kozik, Neil Willits, Yao Luo, Muriel Guittet, Elena Kochetkova, and Richard W. Michelmore: Functional Analysis of the Plant Disease Resistance Gene Pto Using DNA Shuffling
J. Biol. Chem. 2005 280: 23073-23083. First Published on March 23, 2005; doi:10.1074/jbc.M500992200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hideaki Higashi, Kazuyuki Yokoyama, Yumiko Fujii, Shumei Ren, Hitomi Yuasa, Iraj Saadat, Naoko Murata-Kamiya, Takeshi Azuma, and Masanori Hatakeyama: EPIYA Motif Is a Membrane-targeting Signal of Helicobacter pylori Virulence Factor CagA in Mammalian Cells
J. Biol. Chem. 2005 280: 23130-23137. First Published on April 13, 2005; doi:10.1074/jbc.M503583200 [Abstract] [Full Text] [PDF]

Jeong-a Kim, Deborah C. Yeh, Marel Ver, Yunhua Li, Andrea Carranza, Thomas P. Conrads, Timothy D. Veenstra, Maureen A. Harrington, and Michael J. Quon: Phosphorylation of Ser²⁴ in the Pleckstrin Homology Domain of Insulin Receptor Substrate-1 by Mouse Pelle-like Kinase/Interleukin-1 Receptor-associated Kinase: CROSS-TALK BETWEEN INFLAMMATORY SIGNALING AND INSULIN SIGNALING THAT MAY CONTRIBUTE TO INSULIN RESISTANCE
J. Biol. Chem. 2005 280: 23173-23183. First Published on April 22, 2005; doi:10.1074/jbc.M501439200 [Abstract] [Full Text] [PDF]

Geneviève Laroche, Moulay Driss Rochdi, Stéphane A. Laporte, and Jean-Luc Parent: Involvement of Actin in Agonist-induced Endocytosis of the G Protein-coupled Receptor for Thromboxane A₂: OVERCOMING OF ACTIN DISRUPTION BY ARRESTIN-3 BUT NOT ARRESTIN-2
J. Biol. Chem. 2005 280: 23215-23224. First Published on April 20, 2005; doi:10.1074/jbc.M414071200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jean-Philip Truman, Nuri Gueven, Martin Lavin, Steven Leibel, Richard Kolesnick, Zvi Fuks, and Adriana Haimovitz-Friedman: Down-regulation of ATM Protein Sensitizes Human Prostate Cancer Cells to Radiation-induced Apoptosis
J. Biol. Chem. 2005 280: 23262-23272. First Published on April 18, 2005; doi:10.1074/jbc.M503701200 [Abstract] [Full Text] [PDF]

Stephanie M. Bozonet, Victoria J. Findlay, Alison M. Day, Jannine Cameron, Elizabeth A. Veal, and Brian A. Morgan: Oxidation of a Eukaryotic 2-Cys Peroxiredoxin Is a Molecular Switch Controlling the Transcriptional Response to Increasing Levels of Hydrogen Peroxide
J. Biol. Chem. 2005 280: 23319-23327. First Published on April 11, 2005; doi:10.1074/jbc.M502757200 [Abstract] [Full Text] [PDF]

Kevin Pruitt, Aylin S. Ülkü, Karen Frantz, Rafael J. Rojas, Vanessa M. Muniz-Medina, Vivek M. Rangnekar, Channing J. Der, and Janiel M. Shields: Ras-mediated Loss of the Pro-apoptotic Response Protein Par-4 Is Mediated by DNA Hypermethylation through Raf-independent and Raf-dependent Signaling Cascades in Epithelial Cells
J. Biol. Chem. 2005 280: 23363-23370. First Published on April 14, 2005; doi:10.1074/jbc.M503083200 [Abstract] [Full Text] [PDF]

Justin P. Huddleson, Nisar Ahmad, Seetha Srinivasan, and Jerry B Lingrel: Induction of KLF2 by Fluid Shear Stress Requires a Novel Promoter Element Activated by a Phosphatidylinositol 3-Kinase-dependent Chromatin-remodeling Pathway
J. Biol. Chem. 2005 280: 23371-23379. First Published on April 15, 2005; doi:10.1074/jbc.M413839200 [Abstract] [Full Text] [PDF]

Dale D. Tang, Wenwu Zhang, and Susan J. Gunst: The Adapter Protein CrkII Regulates Neuronal Wiskott-Aldrich Syndrome Protein, Actin Polymerization, and Tension Development during Contractile Stimulation of Smooth Muscle
J. Biol. Chem. 2005 280: 23380-23389. First Published on April 17, 2005; doi:10.1074/jbc.M413390200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Shuanhu Zhou, Stanislav Lechpammer, Joel S. Greenberger, and Julie Glowacki: Hypoxia Inhibition of Adipocytogenesis in Human Bone Marrow Stromal Cells Requires Transforming Growth Factor- ${beta}$ /Smad3 Signaling
J. Biol. Chem. 2005 280: 22688-22696. First Published on April 20, 2005; doi:10.1074/jbc.M412953200 [Abstract] [Full Text] [PDF]

Kavita C. Gokhale, Gary P. Newnam, Michael Y. Sherman, and Yury O. Chernoff: Modulation of Prion-dependent Polyglutamine Aggregation and Toxicity by Chaperone Proteins in the Yeast Model
J. Biol. Chem. 2005 280: 22809-22818. First Published on April 11, 2005; doi:10.1074/jbc.M500390200 [Abstract] [Full Text] [PDF]

Rudolf Pullmann, Jr., Magdalena Juhaszova, Isabel López de Silanes, Tomoko Kawai, Krystyna Mazan-Mamczarz, Marc K. Halushka, and Myriam Gorospe: Enhanced Proliferation of Cultured Human Vascular Smooth Muscle Cells Linked to Increased Function of RNA-binding Protein HuR
J. Biol. Chem. 2005 280: 22819-22826. First Published on April 11, 2005; doi:10.1074/jbc.M501106200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Matthew J. Hannah, Paul Skehel, Muriel Erent, Laura Knipe, David Ogden, and Tom Carter: Differential Kinetics of Cell Surface Loss of von Willebrand Factor and Its Propolypeptide after Secretion from Weibel-Palade Bodies in Living Human Endothelial Cells
J. Biol. Chem. 2005 280: 22827-22830. First Published on April 14, 2005; doi:10.1074/jbc.M412547200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Janos Molnar, Zsuzsanna Ujfaludi, Sheri F. T. Fong, John A. Bollinger, Girma Waro, Ben Fogelgren, David M. Dooley, Matyas Mink, and Katalin Csiszar: Drosophila Lysyl Oxidases Dmloxl-1 and Dmloxl-2 Are Differentially Expressed and the Active DmLOXL-1 Influences Gene Expression and Development
J. Biol. Chem. 2005 280: 22977-22985. First Published on April 4, 2005; doi:10.1074/jbc.M503006200 [Abstract] [Full Text] [PDF]

Inna N. Rybakova and James M. Ervasti: Identification of Spectrin-like Repeats Required for High Affinity Utrophin-Actin Interaction
J. Biol. Chem. 2005 280: 23018-23023. First Published on April 11, 2005; doi:10.1074/jbc.M502530200 [Abstract] [Full Text] [PDF]

Isabelle Gerin, Vernon W. Dolinsky, Jonathan G. Shackman, Robert T. Kennedy, Shian-Huey Chiang, Charles F. Burant, Knut R. Steffensen, Jan-Åke Gustafsson, and Ormond A. MacDougald: LXR ${beta}$ Is Required for Adipocyte Growth, Glucose Homeostasis, and ${beta}$ Cell Function
J. Biol. Chem. 2005 280: 23024-23031. First Published on April 13, 2005; doi:10.1074/jbc.M412564200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zubaida Saifudeen, Virginia Diavolitsis, Jana Stefkova, Susana Dipp, Hao Fan, and Samir S. El-Dahr: Spatiotemporal Switch from ${Delta}$ Np73 to TAp73 Isoforms during Nephrogenesis: IMPACT ON DIFFERENTIATION GENE EXPRESSION
J. Biol. Chem. 2005 280: 23094-23102. First Published on April 1, 2005; doi:10.1074/jbc.M414575200 [Abstract] [Full Text] [PDF]

Ann-Louise Bergström, Henriette Cordes, Nicole Zsurger, Peter M. H. Heegaard, Henning Laursen, and Joëlle Chabry: Amidation and Structure Relaxation Abolish the Neurotoxicity of the Prion Peptide PrP106–126 in Vivo and in Vitro
J. Biol. Chem. 2005 280: 23114-23121. First Published on April 11, 2005; doi:10.1074/jbc.M500210200 [Abstract] [Full Text] [PDF]

Elena Solomaha, Frances L. Szeto, Mohammed A. Yousef, and H. Clive Palfrey: Kinetics of Src Homology 3 Domain Association with the Proline-rich Domain of Dynamins: SPECIFICITY, OCCLUSION, AND THE EFFECTS OF PHOSPHORYLATION
J. Biol. Chem. 2005 280: 23147-23156. First Published on April 17, 2005; doi:10.1074/jbc.M501745200 [Abstract] [Full Text] [PDF]

Seiko Masuda, Makoto Murakami, Yasukazu Takanezawa, Junken Aoki, Hiroyuki Arai, Yukio Ishikawa, Toshiharu Ishii, Manabu Arioka, and Ichiro Kudo: Neuronal Expression and Neuritogenic Action of Group X Secreted Phospholipase A₂
J. Biol. Chem. 2005 280: 23203-23214. First Published on March 21, 2005; doi:10.1074/jbc.M500985200 [Abstract] [Full Text] [PDF]

Yong Kim, Hiroe Ohyama, Vipel Patel, Marxa Figueiredo, and David T. Wong: Mutation of Cys¹⁰⁵ Inhibits Dimerization of p12^CDK2-AP1 and Its Growth Suppressor Effect
J. Biol. Chem. 2005 280: 23273-23279. First Published on April 19, 2005; doi:10.1074/jbc.M412929200 [Abstract] [Full Text] [PDF]

Paul LaPointe, Xin Wei, and Jean Gariépy: A Role for the Protease-sensitive Loop Region of Shiga-like Toxin 1 in the Retrotranslocation of Its A₁ Domain from the Endoplasmic Reticulum Lumen
J. Biol. Chem. 2005 280: 23310-23318. First Published on April 7, 2005; doi:10.1074/jbc.M414193200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Colin P. Johnson, Ichiro Fujimoto, Urs Rutishauser, and Deborah E. Leckband: Direct evidence that neural cell adhesion molecule (NCAM) polysialylation increases intermembrane repulsion and abrogates adhesion. Vol. 280 (2005) 137–145
J. Biol. Chem. 2005 280: 23424. [Full Text] [PDF]

Paul R. Graves, Karen M. Winkfield, and Timothy A. J. Haystead: Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation. Vol. 280 (2005) 9363–9374
J. Biol. Chem. 2005 280: 23424-a. [Full Text] [PDF]