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Table of Contents: Jul 22 2005; 280 (29)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption] [Table of Contents (PDF)] [Masthead (PDF)]
       Papers Of The Week
       Classics
       Minireviews
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       Protein Synthesis, Post-Translation Modification, and Degradation
       Genomics, Proteomics, and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Papers Of The Week:

Gene Expression during Frog Development
J. Biol. Chem. 2005 280: e99935. [Full Text]  


Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
Bernard L. Horecker's Contributions to Elucidating the Pentose Phosphate Pathway
THE ENZYMATIC CONVERSION OF 6-PHOSPHOGLUCONATE TO RIBULOSE-5-PHOSPHATE AND RIBOSE-5-PHOSPHATE (B. L. Horecker, P. Z. Smyrniotis, and J. E. Seegmiller J. Biol. Chem. 193, 383-396)
J. Biol. Chem. 2005 280: e26. [Full Text]  


Minireviews:

Henry C. Hsia and Jean E. Schwarzbauer
Meet the Tenascins: Multifunctional and Mysterious
J. Biol. Chem. 2005 280: 26641-26644. First Published on June 2, 2005; doi:10.1074/jbc.R500005200 [Full Text] [PDF]  


Accelerated Publications:

Haruhiko Sakuraba, Hideaki Tsuge, Kazunari Yoneda, Nobuhiko Katunuma, and Toshihisa Ohshima
Crystal Structure of the NAD Biosynthetic Enzyme Quinolinate Synthase
J. Biol. Chem. 2005 280: 26645-26648. First Published on June 3, 2005; doi:10.1074/jbc.C500192200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Andrew K. P. Taggart, Jukka Kero, Xiaodong Gan, Tian-Quan Cai, Kang Cheng, Marc Ippolito, Ning Ren, Rebecca Kaplan, Kenneth Wu, Tsuei-Ju Wu, Lan Jin, Chen Liaw, Ruoping Chen, Jeremy Richman, Daniel Connolly, Stefan Offermanns, Samuel D. Wright, and M. Gerard Waters
(D)-{beta}-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G
J. Biol. Chem. 2005 280: 26649-26652. First Published on June 1, 2005; doi:10.1074/jbc.C500213200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Kerri Kobryn, Alex B. Burgin, and George Chaconas
Uncoupling the Chemical Steps of Telomere Resolution by ResT
J. Biol. Chem. 2005 280: 26788-26795. First Published on May 23, 2005; doi:10.1074/jbc.M504530200 [Abstract] [Full Text] [PDF]  

Dmitry V. Bugreev, Efim I. Golub, Alicja Z. Stasiak, Andrzej Stasiak, and Alexander V. Mazin
Activation of Human Meiosis-specific Recombinase Dmc1 by Ca2+
J. Biol. Chem. 2005 280: 26886-26895. First Published on May 25, 2005; doi:10.1074/jbc.M502248200 [Abstract] [Full Text] [PDF]  

Seung-Joo Lee and Charles C. Richardson
Acidic Residues in the Nucleotide-binding Site of the Bacteriophage T7 DNA Primase
J. Biol. Chem. 2005 280: 26984-26991. First Published on May 25, 2005; doi:10.1074/jbc.M504817200 [Abstract] [Full Text] [PDF]  

Hironori Kawakami, Kenji Keyamura, and Tsutomu Katayama
Formation of an ATP-DnaA-specific Initiation Complex Requires DnaA Arginine 285, a Conserved Motif in the AAA+ Protein Family
J. Biol. Chem. 2005 280: 27420-27430. First Published on May 17, 2005; doi:10.1074/jbc.M502764200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Kenichi Imai, Kenji Nakata, Kazuaki Kawai, Takaichi Hamano, Nan Mei, Hiroshi Kasai, and Takashi Okamoto
Induction of OGG1 Gene Expression by HIV-1 Tat
J. Biol. Chem. 2005 280: 26701-26713. First Published on June 1, 2005; doi:10.1074/jbc.M503313200 [Abstract] [Full Text] [PDF]  

Kristina L. Brady, Stephen N. Ponnampalam, Michael J. Bumbulis, and David R. Setzer
Mutations in TFIIIA That Increase Stability of the TFIIIA-5 S rRNA Gene Complex: UNUSUAL EFFECTS ON THE KINETICS OF COMPLEX ASSEMBLY AND DISSOCIATION
J. Biol. Chem. 2005 280: 26743-26750. First Published on May 11, 2005; doi:10.1074/jbc.M502677200 [Abstract] [Full Text] [PDF]  

Nicoleta C. Arva, Tamara R. Gopen, Kathryn E. Talbott, Latoya E. Campbell, Agustin Chicas, David E. White, Gareth L. Bond, Arnold J. Levine, and Jill Bargonetti
A Chromatin-associated and Transcriptionally Inactive p53-Mdm2 Complex Occurs in mdm2 SNP309 Homozygous Cells
J. Biol. Chem. 2005 280: 26776-26787. First Published on May 20, 2005; doi:10.1074/jbc.M505203200 [Abstract] [Full Text] [PDF]  

Shulamit Etzioni, Anat Yafe, Samer Khateb, Pnina Weisman-Shomer, Eyal Bengal, and Michael Fry
Homodimeric MyoD Preferentially Binds Tetraplex Structures of Regulatory Sequences of Muscle-specific Genes
J. Biol. Chem. 2005 280: 26805-26812. First Published on May 27, 2005; doi:10.1074/jbc.M500820200 [Abstract] [Full Text] [PDF]  

Habib A. Mohamed, Weizhe Yao, Diasinou Fioravante, Paul D. Smolen, and John H. Byrne
cAMP-response Elements in Aplysia creb1, creb2, and Ap-uch Promoters: IMPLICATIONS FOR FEEDBACK LOOPS MODULATING LONG TERM MEMORY
J. Biol. Chem. 2005 280: 27035-27043. First Published on May 11, 2005; doi:10.1074/jbc.M502541200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Laurent Loiseau, Sandrine Ollagnier-de Choudens, David Lascoux, Eric Forest, Marc Fontecave, and Frédéric Barras
Analysis of the Heteromeric CsdA-CsdE Cysteine Desulfurase, Assisting Fe-S Cluster Biogenesis in Escherichia coli
J. Biol. Chem. 2005 280: 26760-26769. First Published on May 18, 2005; doi:10.1074/jbc.M504067200 [Abstract] [Full Text] [PDF]  

Vladimir Zeenko and Daniel R. Gallie
Cap-independent Translation of Tobacco Etch Virus Is Conferred by an RNA Pseudoknot in the 5'-Leader
J. Biol. Chem. 2005 280: 26813-26824. First Published on May 23, 2005; doi:10.1074/jbc.M503576200 [Abstract] [Full Text] [PDF]  

Minna Poukkula, Aura Kaunisto, Ville Hietakangas, Konstantin Denessiouk, Tuire Katajamäki, Mark S. Johnson, Lea Sistonen, and John E. Eriksson
Rapid Turnover of c-FLIPshort Is Determined by Its Unique C-terminal Tail
J. Biol. Chem. 2005 280: 27345-27355. First Published on May 10, 2005; doi:10.1074/jbc.M504019200 [Abstract] [Full Text] [PDF]  

Dario C. Ramirez, Sandra E. Gomez Mejiba, and Ronald P. Mason
Copper-catalyzed Protein Oxidation and Its Modulation by Carbon Dioxide: ENHANCEMENT OF PROTEIN RADICALS IN CELLS
J. Biol. Chem. 2005 280: 27402-27411. First Published on May 19, 2005; doi:10.1074/jbc.M504241200 [Abstract] [Full Text] [PDF]  

Claudia Esser, Martin Scheffner, and Jörg Höhfeld
The Chaperone-associated Ubiquitin Ligase CHIP Is Able to Target p53 for Proteasomal Degradation
J. Biol. Chem. 2005 280: 27443-27448. First Published on May 23, 2005; doi:10.1074/jbc.M501574200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:

Vincent Laizé, Paulo Martel, Carla S. B. Viegas, Paul A. Price, and M. Leonor Cancela
Evolution of Matrix and Bone {gamma}-Carboxyglutamic Acid Proteins in Vertebrates
J. Biol. Chem. 2005 280: 26659-26668. First Published on April 23, 2005; doi:10.1074/jbc.M500257200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Nathan R. Deleault, James C. Geoghegan, Koren Nishina, Richard Kascsak, R. Anthony Williamson, and Surachai Supattapone
Protease-resistant Prion Protein Amplification Reconstituted with Partially Purified Substrates and Synthetic Polyanions
J. Biol. Chem. 2005 280: 26873-26879. First Published on May 24, 2005; doi:10.1074/jbc.M503973200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Sylvain Bieler, Lisbell Estrada, Rosalba Lagos, Marcelo Baeza, Joaquín Castilla, and Claudio Soto
Amyloid Formation Modulates the Biological Activity of a Bacterial Protein
J. Biol. Chem. 2005 280: 26880-26885. First Published on May 25, 2005; doi:10.1074/jbc.M502031200 [Abstract] [Full Text] [PDF]  

Hassan Javanbakht, Felipe Diaz-Griffero, Matthew Stremlau, Zhihai Si, and Joseph Sodroski
The Contribution of RING and B-box 2 Domains to Retroviral Restriction Mediated by Monkey TRIM5{alpha}
J. Biol. Chem. 2005 280: 26933-26940. First Published on May 15, 2005; doi:10.1074/jbc.M502145200 [Abstract] [Full Text] [PDF]  

Lei Wang, Andrea Piserchio, and Dale F. Mierke
Structural Characterization of the Intermolecular Interactions of Synapse-associated Protein-97 with the NR2B Subunit of N-Methyl-D-aspartate Receptors
J. Biol. Chem. 2005 280: 26992-26996. First Published on June 1, 2005; doi:10.1074/jbc.M503555200 [Abstract] [Full Text] [PDF]  

Weizhe Hong, Wangwang Jiao, Jicheng Hu, Junrui Zhang, Chong Liu, Xinmiao Fu, Dan Shen, Bin Xia, and Zengyi Chang
Periplasmic Protein HdeA Exhibits Chaperone-like Activity Exclusively within Stomach pH Range by Transforming into Disordered Conformation
J. Biol. Chem. 2005 280: 27029-27034. First Published on May 23, 2005; doi:10.1074/jbc.M503934200 [Abstract] [Full Text] [PDF]  

Tatyana Sandalova, Jakob Michaëlsson, Robert A. Harris, Jacob Odeberg, Gunter Schneider, Klas Kärre, and Adnane Achour
A Structural Basis for CD8+ T Cell-dependent Recognition of Non-homologous Peptide Ligands: IMPLICATIONS FOR MOLECULAR MIMICRY IN AUTOREACTIVITY
J. Biol. Chem. 2005 280: 27069-27075. First Published on April 21, 2005; doi:10.1074/jbc.M500927200 [Abstract] [Full Text] [PDF]  

Bernard Gilquin, Sandrine Braud, Mats A. L. Eriksson, Benoît Roux, Timothy D. Bailey, Birgit T. Priest, Maria L. Garcia, André Ménez, and Sylvaine Gasparini
A Variable Residue in the Pore of Kv1 Channels Is Critical for the High Affinity of Blockers from Sea Anemones and Scorpions
J. Biol. Chem. 2005 280: 27093-27102. First Published on May 12, 2005; doi:10.1074/jbc.M413626200 [Abstract] [Full Text] [PDF]  

Martin Clément, Stéphane S. Martin, Marie-Ève Beaulieu, Caroline Chamberland, Pierre Lavigne, Richard Leduc, Gaétan Guillemette, and Emanuel Escher
Determining the Environment of the Ligand Binding Pocket of the Human Angiotensin II Type I (hAT1) Receptor Using the Methionine Proximity Assay
J. Biol. Chem. 2005 280: 27121-27129. First Published on May 12, 2005; doi:10.1074/jbc.M413653200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Daniele de Sanctis, Sylvia Dewilde, Clemens Vonrhein, Alessandra Pesce, Luc Moens, Paolo Ascenzi, Thomas Hankeln, Thorsten Burmester, Marco Ponassi, Marco Nardini, and Martino Bolognesi
Bishistidyl Heme Hexacoordination, a Key Structural Property in Drosophila melanogaster Hemoglobin
J. Biol. Chem. 2005 280: 27222-27229. First Published on May 24, 2005; doi:10.1074/jbc.M503814200 [Abstract] [Full Text] [PDF]  

Eric M. Norstrom and James A. Mastrianni
The AGAAAAGA Palindrome in PrP Is Required to Generate a Productive PrPSc-PrPC Complex That Leads to Prion Propagation
J. Biol. Chem. 2005 280: 27236-27243. First Published on May 25, 2005; doi:10.1074/jbc.M413441200 [Abstract] [Full Text] [PDF]  

Amy Jacobs, Jayita Sen, Lijun Rong, and Michael Caffrey
Alanine Scanning Mutants of the HIV gp41 Loop
J. Biol. Chem. 2005 280: 27284-27288. First Published on May 24, 2005; doi:10.1074/jbc.M414411200 [Abstract] [Full Text] [PDF]  

Jana Narasimhan, Ming Wang, Zhuji Fu, Jennifer M. Klein, Arthur L. Haas, and Jung-Ja P. Kim
Crystal Structure of the Interferon-induced Ubiquitin-like Protein ISG15
J. Biol. Chem. 2005 280: 27356-27365. First Published on May 24, 2005; doi:10.1074/jbc.M502814200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Neta Sal-Man, Doron Gerber, and Yechiel Shai
The Identification of a Minimal Dimerization Motif QXXS That Enables Homo- and Hetero-association of Transmembrane Helices in Vivo
J. Biol. Chem. 2005 280: 27449-27457. First Published on May 23, 2005; doi:10.1074/jbc.M503095200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Christina Hörnig, Dana Albert, Lutz Fischer, Michael Hörnig, Olof Rådmark, Dieter Steinhilber, and Oliver Werz
1-Oleoyl-2-acetylglycerol Stimulates 5-Lipoxygenase Activity via a Putative (Phospho)lipid Binding Site within the N-terminal C2-like Domain
J. Biol. Chem. 2005 280: 26913-26921. First Published on May 27, 2005; doi:10.1074/jbc.M500068200 [Abstract] [Full Text] [PDF]  

Kristen E. Mengwasser, Leslie A. Bush, Peter Shih, Angelene M. Cantwell, and Enrico Di Cera
Hirudin Binding Reveals Key Determinants of Thrombin Allostery
J. Biol. Chem. 2005 280: 26997-27003. First Published on May 27, 2005; doi:10.1074/jbc.M502678200 [Abstract] [Full Text] [PDF]  

Hanan L. Messiha, Neil C. Bruce, Benedict M. Sattelle, Michael J. Sutcliffe, Andrew W. Munro, and Nigel S. Scrutton
Role of Active Site Residues and Solvent in Proton Transfer and the Modulation of Flavin Reduction Potential in Bacterial Morphinone Reductase
J. Biol. Chem. 2005 280: 27103-27110. First Published on May 19, 2005; doi:10.1074/jbc.M502293200 [Abstract] [Full Text] [PDF]  

Miguel St-Jean, Julien Lafrance-Vanasse, Brigitte Liotard, and Jurgen Sygusch
High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: SUBSTRATE CLEAVAGE AND INDUCED FIT
J. Biol. Chem. 2005 280: 27262-27270. First Published on May 3, 2005; doi:10.1074/jbc.M502413200 [Abstract] [Full Text] [PDF]  

Robert Schnell, Tatyana Sandalova, Ulf Hellman, Ylva Lindqvist, and Gunter Schneider
Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis Is a Sulfite Reductase with a Covalent Cys-Tyr Bond in the Active Site
J. Biol. Chem. 2005 280: 27319-27328. First Published on May 24, 2005; doi:10.1074/jbc.M502560200 [Abstract] [Full Text] [PDF]  

Michael A. Bukys, Melissa A. Blum, Paul Y. Kim, Nicole Brufatto, Michael E. Nesheim, and Michael Kalafatis
Incorporation of Factor Va into Prothrombinase Is Required for Coordinated Cleavage of Prothrombin by Factor Xa
J. Biol. Chem. 2005 280: 27393-27401. First Published on May 16, 2005; doi:10.1074/jbc.M503435200 [Abstract] [Full Text] [PDF]  

Changsuek Yon, Tadahisa Teramoto, Niklaus Mueller, Jessica Phelan, Vannakambadi K. Ganesh, Krishna H. M. Murthy, and R. Padmanabhan
Modulation of the Nucleoside Triphosphatase/RNA Helicase and 5'-RNA Triphosphatase Activities of Dengue Virus Type 2 Nonstructural Protein 3 (NS3) by Interaction with NS5, the RNA-dependent RNA Polymerase
J. Biol. Chem. 2005 280: 27412-27419. First Published on May 24, 2005; doi:10.1074/jbc.M501393200 [Abstract] [Full Text] [PDF]  

Guang Yang, Yaping Gao, Jie Dong, Chuan Liu, Yanning Xue, Ming Fan, Beifen Shen, and Ningsheng Shao
A Novel Peptide Screened by Phage Display Can Mimic TRAP Antigen Epitope against Staphylococcus aureus Infections
J. Biol. Chem. 2005 280: 27431-27435. First Published on May 19, 2005; doi:10.1074/jbc.M501127200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Stephen C. Rogers, Afshin Khalatbari, Peter W. Gapper, Michael P. Frenneaux, and Philip E. James
Detection of Human Red Blood Cell-bound Nitric Oxide
J. Biol. Chem. 2005 280: 26720-26728. First Published on May 6, 2005; doi:10.1074/jbc.M501179200 [Abstract] [Full Text] [PDF]  

Daan M. van den Brink, Joram N. I. van Miert, Georges Dacremont, Jean-François Rontani, and Ronald J. A. Wanders
Characterization of the Final Step in the Conversion of Phytol into Phytanic Acid
J. Biol. Chem. 2005 280: 26838-26844. First Published on May 2, 2005; doi:10.1074/jbc.M501861200 [Abstract] [Full Text] [PDF]  

Jane A. Potter, Paul K. Fyfe, Dmitrij Frolov, Marion C. Wakeham, Rienk van Grondelle, Bruno Robert, and Michael R. Jones
Strong Effects of an Individual Water Molecule on the Rate of Light-driven Charge Separation in the Rhodobacter sphaeroides Reaction Center
J. Biol. Chem. 2005 280: 27155-27164. First Published on May 20, 2005; doi:10.1074/jbc.M501961200 [Abstract] [Full Text] [PDF]  

Michael W. Mather, Elisabeth Darrouzet, Maria Valkova-Valchanova, Jason W. Cooley, Michael T. McIntosh, Fevzi Daldal, and Akhil B. Vaidya
Uncovering the Molecular Mode of Action of the Antimalarial Drug Atovaquone Using a Bacterial System
J. Biol. Chem. 2005 280: 27458-27465. First Published on May 24, 2005; doi:10.1074/jbc.M502319200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Marietta Flores-Díaz, Alberto Alape-Girón, Graeme Clark, Bruno Catimel, Yoshio Hirabayashi, Ed Nice, José-María Gutiérrez, Richard Titball, and Monica Thelestam
A Cellular Deficiency of Gangliosides Causes Hypersensitivity to Clostridium perfringens Phospholipase C
J. Biol. Chem. 2005 280: 26680-26689. First Published on May 26, 2005; doi:10.1074/jbc.M500278200 [Abstract] [Full Text] [PDF]  

Geraldine Chow and Warren Knudson
Characterization of Promoter Elements of the Human HYAL-2 Gene
J. Biol. Chem. 2005 280: 26904-26912. First Published on May 27, 2005; doi:10.1074/jbc.M413845200 [Abstract] [Full Text] [PDF]  

Johanna W. A. M. Celie, Eelco D. Keuning, Robert H. J. Beelen, Angelika M. Dräger, Sonja Zweegman, Floortje L. Kessler, Raija Soininen, and Jacob van den Born
Identification of L-selectin Binding Heparan Sulfates Attached to Collagen Type XVIII
J. Biol. Chem. 2005 280: 26965-26973. First Published on May 24, 2005; doi:10.1074/jbc.M502188200 [Abstract] [Full Text] [PDF]  

David J. Mahoney, Barbara Mulloy, Mark J. Forster, Charles D. Blundell, Eric Fries, Caroline M Milner, and Anthony J. Day
Characterization of the Interaction between Tumor Necrosis Factor-stimulated Gene-6 and Heparin: IMPLICATIONS FOR THE INHIBITION OF PLASMIN IN EXTRACELLULAR MATRIX MICROENVIRONMENTS
J. Biol. Chem. 2005 280: 27044-27055. First Published on May 24, 2005; doi:10.1074/jbc.M502068200 [Abstract] [Full Text] [PDF]  

Dorin-Bogdan Borza, Olga Bondar, Selene Colon, Parvin Todd, Yoshikazu Sado, Eric G. Neilson, and Billy G. Hudson
Goodpasture Autoantibodies Unmask Cryptic Epitopes by Selectively Dissociating Autoantigen Complexes Lacking Structural Reinforcement: NOVEL MECHANISMS FOR IMMUNE PRIVILEGE AND AUTOIMMUNE PATHOGENESIS
J. Biol. Chem. 2005 280: 27147-27154. First Published on May 24, 2005; doi:10.1074/jbc.M504050200 [Abstract] [Full Text] [PDF]  

Angel Ashikov, Françoise Routier, Jutta Fuhlrott, Yvonne Helmus, Martin Wild, Rita Gerardy-Schahn, and Hans Bakker
The Human Solute Carrier Gene SLC35B4 Encodes a Bifunctional Nucleotide Sugar Transporter with Specificity for UDP-Xylose and UDP-N-Acetylglucosamine
J. Biol. Chem. 2005 280: 27230-27235. First Published on May 23, 2005; doi:10.1074/jbc.M504783200 [Abstract] [Full Text] [PDF]  

Roger Sandhoff, Rudolf Geyer, Richard Jennemann, Claudia Paret, Eva Kiss, Tadashi Yamashita, Karin Gorgas, Tjeerd P. Sijmonsma, Masao Iwamori, Catherine Finaz, Richard L. Proia, Herbert Wiegandt, and Hermann-Josef Gröne
Novel Class of Glycosphingolipids Involved in Male Fertility
J. Biol. Chem. 2005 280: 27310-27318. First Published on May 25, 2005; doi:10.1074/jbc.M502775200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Lipids and Lipoproteins:

Carol A. Rouzer and Lawrence J. Marnett
Glycerylprostaglandin Synthesis by Resident Peritoneal Macrophages in Response to a Zymosan Stimulus
J. Biol. Chem. 2005 280: 26690-26700. First Published on May 25, 2005; doi:10.1074/jbc.M501021200 [Abstract] [Full Text] [PDF]  

Ambra Pozzi, Ines Macias-Perez, Tristin Abair, Shouzuo Wei, Yan Su, Roy Zent, John R. Falck, and Jorge H. Capdevila
Characterization of 5,6- and 8,9-Epoxyeicosatrienoic Acids (5,6- and 8,9-EET) as Potent in Vivo Angiogenic Lipids
J. Biol. Chem. 2005 280: 27138-27146. First Published on May 24, 2005; doi:10.1074/jbc.M501730200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Wenxin Yu, Mihee Ko, Katsuhiko Yanagisawa, and Makoto Michikawa
Neurodegeneration in Heterozygous Niemann-Pick Type C1 (NPC1) Mouse: IMPLICATION OF HETEROZYGOUS NPC1 MUTATIONS BEING A RISK FOR TAUOPATHY
J. Biol. Chem. 2005 280: 27296-27302. First Published on May 25, 2005; doi:10.1074/jbc.M503922200 [Abstract] [Full Text] [PDF]  

David J. Shields, Susanne Lingrell, Luis B. Agellon, John T. Brosnan, and Dennis E. Vance
Localization-independent Regulation of Homocysteine Secretion by Phosphatidylethanolamine N-Methyltransferase
J. Biol. Chem. 2005 280: 27339-27344. First Published on May 31, 2005; doi:10.1074/jbc.M504658200 [Abstract] [Full Text] [PDF]  

Monilola A. Olayioye, Stefanie Vehring, Peter Müller, Andreas Herrmann, Jürgen Schiller, Christoph Thiele, Geoffrey J. Lindeman, Jane E. Visvader, and Thomas Pomorski
StarD10, a START Domain Protein Overexpressed in Breast Cancer, Functions as a Phospholipid Transfer Protein
J. Biol. Chem. 2005 280: 27436-27442. First Published on May 23, 2005; doi:10.1074/jbc.M413330200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Membrane Transport, Structure, Function, and Biogenesis:

Linda J. Pike, Xianlin Han, and Richard W. Gross
Epidermal Growth Factor Receptors Are Localized to Lipid Rafts That Contain a Balance of Inner and Outer Leaflet Lipids: A SHOTGUN LIPIDOMICS STUDY
J. Biol. Chem. 2005 280: 26796-26804. First Published on May 24, 2005; doi:10.1074/jbc.M503805200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Qin Li, Xiang Luo, and Shmuel Muallem
Regulation of the P2X7 Receptor Permeability to Large Molecules by Extracellular Cl and Na+
J. Biol. Chem. 2005 280: 26922-26927. First Published on May 27, 2005; doi:10.1074/jbc.M504966200 [Abstract] [Full Text] [PDF]  

Pavel Mistrík, Robert Mader, Stylianos Michalakis, Martha Weidinger, Alexander Pfeifer, and Martin Biel
The Murine HCN3 Gene Encodes a Hyperpolarization-activated Cation Channel with Slow Kinetics and Unique Response to Cyclic Nucleotides
J. Biol. Chem. 2005 280: 27056-27061. First Published on May 27, 2005; doi:10.1074/jbc.M502696200 [Abstract] [Full Text] [PDF]  

Mar Castillo, José Mulet, Luis M. Gutiérrez, José A. Ortiz, Francisco Castelán, Susana Gerber, Salvador Sala, Francisco Sala, and Manuel Criado
Dual Role of the RIC-3 Protein in Trafficking of Serotonin and Nicotinic Acetylcholine Receptors
J. Biol. Chem. 2005 280: 27062-27068. First Published on May 31, 2005; doi:10.1074/jbc.M503746200 [Abstract] [Full Text] [PDF]  

Adele Gibson, Alan P. Lewis, Karen Affleck, Alan J. Aitken, Eric Meldrum, and Nicola Thompson
hCLCA1 and mCLCA3 Are Secreted Non-integral Membrane Proteins and Therefore Are Not Ion Channels
J. Biol. Chem. 2005 280: 27205-27212. First Published on May 25, 2005; doi:10.1074/jbc.M504654200 [Abstract] [Full Text] [PDF]  

Marieangela C. Wilson, David Meredith, Jocelyn E. Manning Fox, Christine Manoharan, Andrew J. Davies, and Andrew P. Halestrap
Basigin (CD147) Is the Target for Organomercurial Inhibition of Monocarboxylate Transporter Isoforms 1 and 4: THE ANCILLARY PROTEIN FOR THE INSENSITIVE MCT2 IS EMBIGIN (gp70)
J. Biol. Chem. 2005 280: 27213-27221. First Published on May 24, 2005; doi:10.1074/jbc.M411950200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Ruben K. Dagda, Chris A. Barwacz, J. Thomas Cribbs, and Stefan Strack
Unfolding-resistant Translocase Targeting: A NOVEL MECHANISM FOR OUTER MITOCHONDRIAL MEMBRANE LOCALIZATION EXEMPLIFIED BY THE B{beta}2 REGULATORY SUBUNIT OF PROTEIN PHOSPHATASE 2A
J. Biol. Chem. 2005 280: 27375-27382. First Published on May 27, 2005; doi:10.1074/jbc.M503693200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Lisa Y. Lenertz, Byung-Hoon Lee, Xiaoshan Min, Bing-e Xu, Kyle Wedin, Svetlana Earnest, Elizabeth J. Goldsmith, and Melanie H. Cobb
Properties of WNK1 and Implications for Other Family Members
J. Biol. Chem. 2005 280: 26653-26658. First Published on May 9, 2005; doi:10.1074/jbc.M502598200 [Abstract] [Full Text] [PDF]  

Wei Yan, Christopher M. Jenkins, Xianlin Han, David J. Mancuso, Harold F. Sims, Kui Yang, and Richard W. Gross
The Highly Selective Production of 2-Arachidonoyl Lysophosphatidylcholine Catalyzed by Purified Calcium-independent Phospholipase A2{gamma}: IDENTIFICATION OF A NOVEL ENZYMATIC MEDIATOR FOR THE GENERATION OF A KEY BRANCH POINT INTERMEDIATE IN EICOSANOID SIGNALING
J. Biol. Chem. 2005 280: 26669-26679. First Published on May 20, 2005; doi:10.1074/jbc.M502358200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Kush M. Parmar, Vinod Nambudiri, Guohao Dai, H. Benjamin Larman, Michael A. Gimbrone, Jr., and Guillermo García-Cardeña
Statins Exert Endothelial Atheroprotective Effects via the KLF2 Transcription Factor
J. Biol. Chem. 2005 280: 26714-26719. First Published on May 4, 2005; doi:10.1074/jbc.C500144200 [Abstract] [Full Text] [PDF]  

Purva Bali, Michael Pranpat, James Bradner, Maria Balasis, Warren Fiskus, Fei Guo, Kathy Rocha, Sandhya Kumaraswamy, Sandhya Boyapalle, Peter Atadja, Edward Seto, and Kapil Bhalla
Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90: A NOVEL BASIS FOR ANTILEUKEMIA ACTIVITY OF HISTONE DEACETYLASE INHIBITORS
J. Biol. Chem. 2005 280: 26729-26734. First Published on June 2, 2005; doi:10.1074/jbc.C500186200 [Abstract] [Full Text] [PDF]  

Qing Zhao, Zhiwei He, Nanyue Chen, Yong-Yeon Cho, Feng Zhu, Chengrong Lu, Wei-ya Ma, Ann M. Bode, and Zigang Dong
2-Arachidonoylglycerol Stimulates Activator Protein-1-dependent Transcriptional Activity and Enhances Epidermal Growth Factor-induced Cell Transformation in JB6 P+ Cells
J. Biol. Chem. 2005 280: 26735-26742. First Published on May 10, 2005; doi:10.1074/jbc.M412828200 [Abstract] [Full Text] [PDF]  

Michael C. Lawrence, Kathleen McGlynn, Byung-Hyun Park, and Melanie H. Cobb
ERK1/2-dependent Activation of Transcription Factors Required for Acute and Chronic Effects of Glucose on the Insulin Gene Promoter
J. Biol. Chem. 2005 280: 26751-26759. First Published on May 16, 2005; doi:10.1074/jbc.M503158200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Mikhail Semënov, Keiko Tamai, and Xi He
SOST Is a Ligand for LRP5/LRP6 and a Wnt Signaling Inhibitor
J. Biol. Chem. 2005 280: 26770-26775. First Published on May 20, 2005; doi:10.1074/jbc.M504308200 [Abstract] [Full Text] [PDF]  

Jyoti P. Mishra, Sasmita Mishra, Katrina Gee, and Ashok Kumar
Differential Involvement of Calmodulin-dependent Protein Kinase II-activated AP-1 and c-Jun N-terminal Kinase-activated EGR-1 Signaling Pathways in Tumor Necrosis Factor-{alpha} and Lipopolysaccharide-induced CD44 Expression in Human Monocytic Cells
J. Biol. Chem. 2005 280: 26825-26837. First Published on May 27, 2005; doi:10.1074/jbc.M500244200 [Abstract] [Full Text] [PDF]  

Jae J. Song and Yong J. Lee
Cross-talk between JIP3 and JIP1 during Glucose Deprivation: SEK1-JNK2 AND Akt1 ACT AS MEDIATORS
J. Biol. Chem. 2005 280: 26845-26855. First Published on May 23, 2005; doi:10.1074/jbc.M502318200 [Abstract] [Full Text] [PDF]  

Linda Fredriksson, Monika Ehnman, Christina Fieber, and Ulf Eriksson
Structural Requirements for Activation of Latent Platelet-derived Growth Factor CC by Tissue Plasminogen Activator
J. Biol. Chem. 2005 280: 26856-26862. First Published on May 23, 2005; doi:10.1074/jbc.M503388200 [Abstract] [Full Text] [PDF]  

Takahiro Shirogane, Jianping Jin, Xiaolu L. Ang, and J. Wade Harper
SCF{beta}-TRCP Controls Clock-dependent Transcription via Casein Kinase 1-dependent Degradation of the Mammalian Period-1 (Per1) Proteinm
J. Biol. Chem. 2005 280: 26863-26872. First Published on May 24, 2005; doi:10.1074/jbc.M502862200 [Abstract] [Full Text] [PDF]  

Silvana A. Andric, Dragoslava Zivadinovic, Arturo E. Gonzalez-Iglesias, Agnieszka Lachowicz, Melanija Tomic, and Stanko S. Stojilkovic
Endothelin-induced, Long Lasting, and Ca2+ Influx-independent Blockade of Intrinsic Secretion in Pituitary Cells by Gz Subunits
J. Biol. Chem. 2005 280: 26896-26903. First Published on May 26, 2005; doi:10.1074/jbc.M502226200 [Abstract] [Full Text] [PDF]  

Laura K. Antos, Sarah E. Abbey-Hosch, Darcy R. Flora, and Lincoln R. Potter
ATP-independent Activation of Natriuretic Peptide Receptors
J. Biol. Chem. 2005 280: 26928-26932. First Published on May 23, 2005; doi:10.1074/jbc.M505648200 [Abstract] [Full Text] [PDF]  

Kan V. Lu, Kimberly A. Jong, Gloria Y. Kim, Jatinder Singh, Ederlyn Q. Dia, Koji Yoshimoto, Maria Y. Wang, Timothy F. Cloughesy, Stanley F. Nelson, and Paul S. Mischel
Differential Induction of Glioblastoma Migration and Growth by Two Forms of Pleiotrophin
J. Biol. Chem. 2005 280: 26953-26964. First Published on May 20, 2005; doi:10.1074/jbc.M502614200 [Abstract] [Full Text] [PDF]  

Denis Touroutine, Rebecca M. Fox, Stephen E. Von Stetina, Anna Burdina, David M. Miller, III, and Janet E. Richmond
acr-16 Encodes an Essential Subunit of the Levamisole-resistant Nicotinic Receptor at the Caenorhabditis elegans Neuromuscular Junction
J. Biol. Chem. 2005 280: 27013-27021. First Published on May 24, 2005; doi:10.1074/jbc.M502818200 [Abstract] [Full Text] [PDF]  

Qingnan Li, Liyu Wu, Denise K. Oelschlager, Mei Wan, Cecil R. Stockard, William E. Grizzle, Ning Wang, Huaiqing Chen, Yi Sun, and Xu Cao
Smad4 Inhibits Tumor Growth by Inducing Apoptosis in Estrogen Receptor-{alpha}-positive Breast Cancer Cells
J. Biol. Chem. 2005 280: 27022-27028. First Published on May 10, 2005; doi:10.1074/jbc.M505071200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Won Jae Lee, Jodie A. Robinson, Nicola A. Holman, Martin N. McCall, Sarah J. Roberts-Thomson, and Gregory R. Monteith
Antisense-mediated Inhibition of the Plasma Membrane Calcium-ATPase Suppresses Proliferation of MCF-7 Cells
J. Biol. Chem. 2005 280: 27076-27084. First Published on May 23, 2005; doi:10.1074/jbc.M414142200 [Abstract] [Full Text] [PDF]  

Tetsuya Kawakita, Edgar M. Espana, Hua He, Armand Hornia, Lung-Kun Yeh, Jie Ouyang, Chia-Yang Liu, and Scheffer C. G. Tseng
Keratocan Expression of Murine Keratocytes Is Maintained on Amniotic Membrane by Down-regulating Transforming Growth Factor-{beta} Signaling
J. Biol. Chem. 2005 280: 27085-27092. First Published on May 20, 2005; doi:10.1074/jbc.M409567200 [Abstract] [Full Text] [PDF]  

Shengyu Yang and Xin-Yun Huang
Ca2+ Influx through L-type Ca2+ Channels Controls the Trailing Tail Contraction in Growth Factor-induced Fibroblast Cell Migration
J. Biol. Chem. 2005 280: 27130-27137. First Published on May 23, 2005; doi:10.1074/jbc.M501625200 [Abstract] [Full Text] [PDF]  

Mario Gonzalez-Gronow, Uma K. Misra, Govind Gawdi, and Salvatore V. Pizzo
Association of Plasminogen with Dipeptidyl Peptidase IV and Na+/H+ Exchanger Isoform NHE3 Regulates Invasion of Human 1-LN Prostate Tumor Cells
J. Biol. Chem. 2005 280: 27173-27178. First Published on May 23, 2005; doi:10.1074/jbc.M500383200 [Abstract] [Full Text] [PDF]  

Roland Reinehr, Stephan Becker, Andrea Eberle, Susanne Grether-Beck, and Dieter Häussinger
Involvement of NADPH Oxidase Isoforms and Src Family Kinases in CD95-dependent Hepatocyte Apoptosis
J. Biol. Chem. 2005 280: 27179-27194. First Published on May 25, 2005; doi:10.1074/jbc.M414361200 [Abstract] [Full Text] [PDF]  

Jennifer J. Tate, Rajendra Rai, and Terrance G. Cooper
Methionine Sulfoximine Treatment and Carbon Starvation Elicit Snf1-independent Phosphorylation of the Transcription Activator Gln3 in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 27195-27204. First Published on May 23, 2005; doi:10.1074/jbc.M504052200 [Abstract] [Full Text] [PDF]  

Tomonori Hosoya, Atsushi Maruyama, Moon-Il Kang, Yukie Kawatani, Takahiro Shibata, Koji Uchida, Ken Itoh, and Masayuki Yamamoto
Differential Responses of the Nrf2-Keap1 System to Laminar and Oscillatory Shear Stresses in Endothelial Cells
J. Biol. Chem. 2005 280: 27244-27250. First Published on May 25, 2005; doi:10.1074/jbc.M502551200 [Abstract] [Full Text] [PDF]  

Yohan Royer, Judith Staerk, Marcel Costuleanu, Pierre J. Courtoy, and Stefan N. Constantinescu
Janus Kinases Affect Thrombopoietin Receptor Cell Surface Localization and Stability
J. Biol. Chem. 2005 280: 27251-27261. First Published on May 16, 2005; doi:10.1074/jbc.M501376200 [Abstract] [Full Text] [PDF]  

Chris Hague, Leah S. Bernstein, Suneela Ramineni, Zhongjian Chen, Kenneth P. Minneman, and John R. Hepler
Selective Inhibition of {alpha}1A-Adrenergic Receptor Signaling by RGS2 Association with the Receptor Third Intracellular Loop
J. Biol. Chem. 2005 280: 27289-27295. First Published on May 24, 2005; doi:10.1074/jbc.M502365200 [Abstract] [Full Text] [PDF]  

Yongmei Pu, Nicholas A. Perry, Dazhi Yang, Nancy E. Lewin, Noemi Kedei, Derek C. Braun, Sung Hee Choi, Peter M. Blumberg, Susan H. Garfield, James C. Stone, Dehui Duan, and Victor E. Marquez
A Novel Diacylglycerol-lactone Shows Marked Selectivity in Vitro among C1 Domains of Protein Kinase C (PKC) Isoforms {alpha} and {delta} as Well as Selectivity for RasGRP Compared with PKC{alpha}
J. Biol. Chem. 2005 280: 27329-27338. First Published on May 27, 2005; doi:10.1074/jbc.M414132200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Dan Li, Steven Yea, Side Li, Zhu Chen, Goutham Narla, Michaela Banck, Jorge Laborda, Song Tan, Jeffrey M. Friedman, Scott L. Friedman, and Martin J. Walsh
Krüppel-like Factor-6 Promotes Preadipocyte Differentiation through Histone Deacetylase 3-dependent Repression of DLK1
J. Biol. Chem. 2005 280: 26941-26952. First Published on May 25, 2005; doi:10.1074/jbc.M500463200 [Abstract] [Full Text] [PDF]  

Xiong Liu, Shi Shu, Mihály Kovács, and Edward D. Korn
Biological, Biochemical, and Kinetic Effects of Mutations of the Cardiomyopathy Loop of Dictyostelium Myosin II: IMPORTANCE OF ALA400
J. Biol. Chem. 2005 280: 26974-26983. First Published on May 16, 2005; doi:10.1074/jbc.M504453200 [Abstract] [Full Text] [PDF]  

Carolina Segura-Morales, Christina Pescia, Christine Chatellard-Causse, Remy Sadoul, Edouard Bertrand, and Eugenia Basyuk
Tsg101 and Alix Interact with Murine Leukemia Virus Gag and Cooperate with Nedd4 Ubiquitin Ligases during Budding
J. Biol. Chem. 2005 280: 27004-27012. First Published on May 21, 2005; doi:10.1074/jbc.M413735200 [Abstract] [Full Text] [PDF]  

Pia A. J. Huber, Graeme M. Birdsey, Michael J. Lumb, David T. R. Prowse, Tommy J. Perkins, Daniel R. Knight, and Christopher J. Danpure
Peroxisomal Import of Human Alanine:glyoxylate Aminotransferase Requires Ancillary Targeting Information Remote from Its C Terminus
J. Biol. Chem. 2005 280: 27111-27120. First Published on May 23, 2005; doi:10.1074/jbc.M502719200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Bindu D. Paul, Daniel R. Buchholz, Liezhen Fu, and Yun-Bo Shi
Tissue- and Gene-specific Recruitment of Steroid Receptor Coactivator-3 by Thyroid Hormone Receptor during Development
J. Biol. Chem. 2005 280: 27165-27172. First Published on May 18, 2005; doi:10.1074/jbc.M503999200 [Abstract] [Full Text] [PDF] [Summary]  

Andrea Hoffmann, Olena Preobrazhenska, Claas Wodarczyk, Yvonne Medler, Andreas Winkel, Sandra Shahab, Danny Huylebroeck, Gerhard Gross, and Kristin Verschueren
Transforming Growth Factor-{beta}-activated Kinase-1 (TAK1), a MAP3K, Interacts with Smad Proteins and Interferes with Osteogenesis in Murine Mesenchymal Progenitors
J. Biol. Chem. 2005 280: 27271-27283. First Published on May 23, 2005; doi:10.1074/jbc.M503368200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Alberto Lleó, Elaine Waldron, Christine A. F. von Arnim, Lauren Herl, Michele M. Tangredi, Ithan D. Peltan, Dudley K. Strickland, Edward H. Koo, Bradley T. Hyman, Claus U. Pietrzik, and Oksana Berezovska
Low Density Lipoprotein Receptor-related Protein (LRP) Interacts with Presenilin 1 and Is a Competitive Substrate of the Amyloid Precursor Protein (APP) for {gamma}-Secretase
J. Biol. Chem. 2005 280: 27303-27309. First Published on May 25, 2005; doi:10.1074/jbc.M413969200 [Abstract] [Full Text] [PDF]  

Mei Chung Moh, Chunli Zhang, Chunli Luo, Lay Hoon Lee, and Shali Shen
Structural and Functional Analyses of a Novel Ig-like Cell Adhesion Molecule, hepaCAM, in the Human Breast Carcinoma MCF7 Cells
J. Biol. Chem. 2005 280: 27366-27374. First Published on May 25, 2005; doi:10.1074/jbc.M500852200 [Abstract] [Full Text] [PDF]  

Yi Peter Hu, Srinivas Venkateswarlu, Natalia Sergina, Gillian Howell, Patricia St. Clair, Lisa E. Humphrey, Wenhui Li, Jennie Hauser, Elizabeth Zborowska, James K. V. Willson, and Michael G. Brattain
Reorganization of ErbB Family and Cell Survival Signaling after Knock-down of ErbB2 in Colon Cancer Cells
J. Biol. Chem. 2005 280: 27383-27392. First Published on May 11, 2005; doi:10.1074/jbc.M414238200 [Abstract] [Full Text] [PDF]  

Sarawut Jitrapakdee, Marc Slawik, Gema Medina-Gomez, Mark Campbell, John C. Wallace, Jaswinder K. Sethi, Stephen O'Rahilly, and Antonio J. Vidal-Puig
The Peroxisome Proliferator-activated Receptor-{gamma} Regulates Murine Pyruvate Carboxylase Gene Expression in Vivo and in Vitro
J. Biol. Chem. 2005 280: 27466-27476. First Published on May 25, 2005; doi:10.1074/jbc.M503836200 [Abstract] [Full Text] [PDF]  


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