JBC -- Table of Contents (Sep 2 2005, 280, (35))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: The Role of the Acyl Carrier Protein in Fatty Acid Synthesis: the Work of P. Roy Vagelos
Acyl Carrier Protein. VII. THE PRIMARY STRUCTURE OF THE SUBSTRATE-BINDING SITE (Philip W. Majerus, A. W. Alberts, and P. Roy Vagelos J. Biol. Chem. 240, 4723-4726)
Acyl Carrier Protein. III. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS (Philip W. Majerus, A. W. Alberts, and P. Roy Vagelos J. Biol. Chem. 240, 618-621)
J. Biol. Chem. 2005 280: e32. [Full Text]

Accelerated Publications:

Carlos W. Bertoncini, Claudio O. Fernandez, Christian Griesinger, Thomas M. Jovin, and Markus Zweckstetter: Familial Mutants of ${alpha}$ -Synuclein with Increased Neurotoxicity Have a Destabilized Conformation
J. Biol. Chem. 2005 280: 30649-30652. First Published on July 14, 2005; doi:10.1074/jbc.C500288200 [Abstract] [Full Text] [PDF] [Supplemental Data]

DNA: Replication, Repair, and Recombination:

Hong Zang, Qingming Fang, Anthony E. Pegg, and F. Peter Guengerich: Kinetic Analysis of Steps in the Repair of Damaged DNA by Human O⁶-Alkylguanine-DNA Alkyltransferase
J. Biol. Chem. 2005 280: 30873-30881. First Published on July 5, 2005; doi:10.1074/jbc.M505283200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Klaus Dittmann, Claus Mayer, Birgit Fehrenbacher, Martin Schaller, Uma Raju, Luka Milas, David J. Chen, Rainer Kehlbach, and H. Peter Rodemann: Radiation-induced Epidermal Growth Factor Receptor Nuclear Import Is Linked to Activation of DNA-dependent Protein Kinase
J. Biol. Chem. 2005 280: 31182-31189. First Published on July 5, 2005; doi:10.1074/jbc.M506591200 [Abstract] [Full Text] [PDF]

Serge Bergeron, Tina Madathiparambil, and Patrick C. Swanson: Both High Mobility Group (HMG)-boxes and the Acidic Tail of HMGB1 Regulate Recombination-activating Gene (RAG)-mediated Recombination Signal Synapsis and Cleavage in Vitro
J. Biol. Chem. 2005 280: 31314-31324. First Published on July 1, 2005; doi:10.1074/jbc.M503063200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Takashi Osanai, Yu Kanesaki, Takayuki Nakano, Hiroyuki Takahashi, Munehiko Asayama, Makoto Shirai, Minoru Kanehisa, Iwane Suzuki, Norio Murata, and Kan Tanaka: Positive Regulation of Sugar Catabolic Pathways in the Cyanobacterium Synechocystis sp. PCC 6803 by the Group 2 ${sigma}$ Factor SigE
J. Biol. Chem. 2005 280: 30653-30659. First Published on June 8, 2005; doi:10.1074/jbc.M505043200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chiu-Jung Huang, Jan-Gowth Chang, Shinn-Chih Wu, and Kong-Bung Choo: Negative Transcriptional Modulation and Silencing of the Bi-exonic Rnf35 Gene in the Preimplantation Embryo: BINDING OF THE CCAAT-DISPLACEMENT PROTEIN/Cux TO THE UNTRANSLATED EXON 1 SEQUENCE
J. Biol. Chem. 2005 280: 30681-30688. First Published on July 1, 2005; doi:10.1074/jbc.M413144200 [Abstract] [Full Text] [PDF]

Guozhi Xiao, Di Jiang, Chunxi Ge, Zhuoran Zhao, Yumei Lai, Heidi Boules, Mattabhorn Phimphilai, Xiangli Yang, Gerard Karsenty, and Renny T. Franceschi: Cooperative Interactions between Activating Transcription Factor 4 and Runx2/Cbfa1 Stimulate Osteoblast-specific Osteocalcin Gene Expression
J. Biol. Chem. 2005 280: 30689-30696. First Published on July 5, 2005; doi:10.1074/jbc.M500750200 [Abstract] [Full Text] [PDF]

Bogdan Yatsula, Sharon Lin, Andrew J. Read, Amanda Poholek, Kristin Yates, Dongxian Yue, Pei Hui, and Archibald S. Perkins: Identification of Binding Sites of EVI1 in Mammalian Cells
J. Biol. Chem. 2005 280: 30712-30722. First Published on July 8, 2005; doi:10.1074/jbc.M504293200 [Abstract] [Full Text] [PDF]

Hernan Roca, Mattabhorn Phimphilai, Rajaram Gopalakrishnan, Guozhi Xiao, and Renny T. Franceschi: Cooperative Interactions between RUNX2 and Homeodomain Protein-binding Sites Are Critical for the Osteoblast-specific Expression of the Bone Sialoprotein Gene
J. Biol. Chem. 2005 280: 30845-30855. First Published on July 5, 2005; doi:10.1074/jbc.M503942200 [Abstract] [Full Text] [PDF]

Yuichiro Takagi, James Z. Chadick, Joshua A. Davis, and Francisco J. Asturias: Preponderance of Free Mediator in the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 31200-31207. First Published on July 6, 2005; doi:10.1074/jbc.C500150200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Marta Martínez-Vicente, Lucía Yim, Magda Villarroya, Mara Mellado, Enrique Pérez-Payá, Glenn R. Björk, and M.-Eugenia Armengod: Effects of Mutagenesis in the Switch I Region and Conserved Arginines of Escherichia coli MnmE Protein, A GTPase Involved in tRNA Modification
J. Biol. Chem. 2005 280: 30660-30670. First Published on June 27, 2005; doi:10.1074/jbc.M503223200 [Abstract] [Full Text] [PDF]

Shih-Peng Chan and Soo-Chen Cheng: The Prp19-associated Complex Is Required for Specifying Interactions of U5 and U6 with Pre-mRNA during Spliceosome Activation
J. Biol. Chem. 2005 280: 31190-31199. First Published on June 30, 2005; doi:10.1074/jbc.M505060200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Angeliki Fotinopoulou, Maria Tsachaki, Maria Vlavaki, Alexandros Poulopoulos, Agueda Rostagno, Blas Frangione, Jorge Ghiso, and Spiros Efthimiopoulos: BRI2 Interacts with Amyloid Precursor Protein (APP) and Regulates Amyloid ${beta}$ (A ${beta}$ ) Production
J. Biol. Chem. 2005 280: 30768-30772. First Published on July 18, 2005; doi:10.1074/jbc.C500231200 [Abstract] [Full Text] [PDF]

Anne E. McBride, Jeffrey T. Cook, Elizabeth A. Stemmler, Kate L. Rutledge, Kelly A. McGrath, and Jeffrey A. Rubens: Arginine Methylation of Yeast mRNA-binding Protein Npl3 Directly Affects Its Function, Nuclear Export, and Intranuclear Protein Interactions
J. Biol. Chem. 2005 280: 30888-30898. First Published on July 5, 2005; doi:10.1074/jbc.M505831200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rebecca Bilton, Nathalie Mazure, Eric Trottier, Maurice Hattab, Marc-André Déry, Darren E. Richard, Jacques Pouysségur, and M. Christiane Brahimi-Horn: Arrest-defective-1 Protein, an Acetyltransferase, Does Not Alter Stability of Hypoxia-inducible Factor (HIF)-1 ${alpha}$ and Is Not Induced by Hypoxia or HIF
J. Biol. Chem. 2005 280: 31132-31140. First Published on July 1, 2005; doi:10.1074/jbc.M504482200 [Abstract] [Full Text] [PDF]

John T. Swarthout, Sandra Lobo, Lynn Farh, Monica R. Croke, Wendy K. Greentree, Robert J. Deschenes, and Maurine E. Linder: DHHC9 and GCP16 Constitute a Human Protein Fatty Acyltransferase with Specificity for H- and N-Ras
J. Biol. Chem. 2005 280: 31141-31148. First Published on July 6, 2005; doi:10.1074/jbc.M504113200 [Abstract] [Full Text] [PDF]

David K. Rhee, Jose Marcelino, Sulaiman Al-Mayouf, Deborah K. Schelling, Cynthia F. Bartels, Yajun Cui, Ronald Laxer, Raphaela Goldbach-Mansky, and Matthew L. Warman: Consequences of Disease-causing Mutations on Lubricin Protein Synthesis, Secretion, and Post-translational Processing
J. Biol. Chem. 2005 280: 31325-31332. First Published on July 5, 2005; doi:10.1074/jbc.M505401200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Holger Römpler, Angela Schulz, Christian Pitra, Graham Coop, Molly Przeworski, Svante Pääbo, and Torsten Schöneberg: The Rise and Fall of the Chemoattractant Receptor GPR33
J. Biol. Chem. 2005 280: 31068-31075. First Published on June 29, 2005; doi:10.1074/jbc.M503586200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Aldrin V. Gomes, Jingsheng Liang, and James D. Potter: Mutations in Human Cardiac Troponin I That Are Associated with Restrictive Cardiomyopathy Affect Basal ATPase Activity and the Calcium Sensitivity of Force Development
J. Biol. Chem. 2005 280: 30909-30915. First Published on June 15, 2005; doi:10.1074/jbc.M500287200 [Abstract] [Full Text] [PDF]

Atsushi Jinno-Oue, Nobuaki Shimizu, Yasushi Soda, Atsushi Tanaka, Takahiro Ohtsuki, Dai Kurosaki, Yasuo Suzuki, and Hiroo Hoshino: The Synthetic Peptide Derived from the NH₂-terminal Extracellular Region of an Orphan G Protein-coupled Receptor, GPR1, Preferentially Inhibits Infection of X4 HIV-1
J. Biol. Chem. 2005 280: 30924-30934. First Published on May 26, 2005; doi:10.1074/jbc.M500195200 [Abstract] [Full Text] [PDF]

Euiyoung Bae and George N. Phillips, Jr.: Identifying and Engineering Ion Pairs in Adenylate Kinases: INSIGHTS FROM MOLECULAR DYNAMICS SIMULATIONS OF THERMOPHILIC AND MESOPHILIC HOMOLOGUES
J. Biol. Chem. 2005 280: 30943-30948. First Published on July 1, 2005; doi:10.1074/jbc.M504216200 [Abstract] [Full Text] [PDF]

Huanchen Wang, Yudong Liu, Yuxiang Chen, Howard Robinson, and Hengming Ke: Multiple Elements Jointly Determine Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases 4 and 7
J. Biol. Chem. 2005 280: 30949-30955. First Published on July 1, 2005; doi:10.1074/jbc.M504398200 [Abstract] [Full Text] [PDF]

Hideaki Tsuge, Ryushi Kawakami, Haruhiko Sakuraba, Hideo Ago, Masashi Miyano, Kenji Aki, Nobuhiko Katunuma, and Toshihisa Ohshima: Crystal Structure of a Novel FAD-, FMN-, and ATP-containing L-Proline Dehydrogenase Complex from Pyrococcus horikoshii
J. Biol. Chem. 2005 280: 31045-31049. First Published on July 15, 2005; doi:10.1074/jbc.C500234200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Martin Locher, Beatrix Lehnert, Kristina Krauss, Jürgen Heesemann, Michael Groll, and Gottfried Wilharm: Crystal Structure of the Yersinia enterocolitica Type III Secretion Chaperone SycT
J. Biol. Chem. 2005 280: 31149-31155. First Published on July 6, 2005; doi:10.1074/jbc.M500603200 [Abstract] [Full Text] [PDF]

Lin Tang, Ming-Hui Li, Peng Cao, Feng Wang, Wen-Rui Chang, Stéphane Bach, Jens Reinhardt, Yoan Ferandin, Hervé Galons, Yongqin Wan, Nathanael Gray, Laurent Meijer, Tao Jiang, and Dong-Cai Liang: Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives
J. Biol. Chem. 2005 280: 31220-31229. First Published on June 28, 2005; doi:10.1074/jbc.M500805200 [Abstract] [Full Text] [PDF]

Eric Sauvage, Raphaël Herman, Stephanie Petrella, Colette Duez, Fabrice Bouillenne, Jean-Marie Frère, and Paulette Charlier: Crystal Structure of the Actinomadura R39 DD-peptidase Reveals New Domains in Penicillin-binding Proteins
J. Biol. Chem. 2005 280: 31249-31256. First Published on June 29, 2005; doi:10.1074/jbc.M503271200 [Abstract] [Full Text] [PDF]

Min-Feng Hsu, Chih-Jung Kuo, Kai-Ti Chang, Hui-Chuan Chang, Chia-Cheng Chou, Tzu-Ping Ko, Hui-Lin Shr, Gu-Gang Chang, Andrew H.-J. Wang, and Po-Huang Liang: Mechanism of the Maturation Process of SARS-CoV 3CL Protease
J. Biol. Chem. 2005 280: 31257-31266. First Published on March 23, 2005; doi:10.1074/jbc.M502577200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Johannes Fürst, Andreas Schedlbauer, Rosaria Gandini, Maria Lisa Garavaglia, Stefano Saino, Martin Gschwentner, Bettina Sarg, Herbert Lindner, Martin Jakab, Markus Ritter, Claudia Bazzini, Guido Botta, Giuliano Meyer, Georg Kontaxis, Ben C. Tilly, Robert Konrat, and Markus Paulmichl: ICln₁₅₉ Folds into a Pleckstrin Homology Domain-like Structure: INTERACTION WITH KINASES AND THE SPLICING FACTOR LSm4
J. Biol. Chem. 2005 280: 31276-31282. First Published on May 19, 2005; doi:10.1074/jbc.M500541200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Randy K. Bledsoe, Kevin P. Madauss, Jason A. Holt, Christopher J. Apolito, Millard H. Lambert, Kenneth H. Pearce, Thomas B. Stanley, Eugene L. Stewart, Ryan P. Trump, Timothy M. Willson, and Shawn P. Williams: A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor
J. Biol. Chem. 2005 280: 31283-31293. First Published on June 20, 2005; doi:10.1074/jbc.M504098200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Takeshi Hibino: Nonfixed Relationship of the Michaelis Constant and Maximum Velocity with Their Corresponding Rate Constants
J. Biol. Chem. 2005 280: 30671-30680. First Published on June 22, 2005; doi:10.1074/jbc.M412601200 [Abstract] [Full Text] [PDF]

Ker R. Marshall, Min Gong, Leigh Wodke, John H. Lamb, Donald J. L. Jones, Peter B. Farmer, Nigel S. Scrutton, and Andrew W. Munro: The Human Apoptosis-inducing Protein AMID Is an Oxidoreductase with a Modified Flavin Cofactor and DNA Binding Activity
J. Biol. Chem. 2005 280: 30735-30740. First Published on June 15, 2005; doi:10.1074/jbc.M414018200 [Abstract] [Full Text] [PDF]

Diana Dominguez, Jos Tournoy, Dieter Hartmann, Tobias Huth, Kim Cryns, Siska Deforce, Lutgarde Serneels, Ira Espuny Camacho, Els Marjaux, Katleen Craessaerts, Anton J. M. Roebroek, Michael Schwake, Rudi D'Hooge, Patricia Bach, Ulrich Kalinke, Dieder Moechars, Christian Alzheimer, Karina Reiss, Paul Saftig, and Bart De Strooper: Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice
J. Biol. Chem. 2005 280: 30797-30806. First Published on June 29, 2005; doi:10.1074/jbc.M505249200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Emmanuel Psylinakis, Ivo G. Boneca, Konstantinos Mavromatis, Alexandra Deli, Emma Hayhurst, Simon J. Foster, Kjell M. Vårum, and Vassilis Bouriotis: Peptidoglycan N-Acetylglucosamine Deacetylases from Bacillus cereus, Highly Conserved Proteins in Bacillus anthracis
J. Biol. Chem. 2005 280: 30856-30863. First Published on June 16, 2005; doi:10.1074/jbc.M407426200 [Abstract] [Full Text] [PDF]

Richard Clark, Maqsood Ali Ansari, Sheffali Dash, Michael A. Geeves, and Lynne M. Coluccio: Loop 1 of Transducer Region in Mammalian Class I Myosin, Myo1b, Modulates Actin Affinity, ATPase Activity, and Nucleotide Access
J. Biol. Chem. 2005 280: 30935-30942. First Published on June 26, 2005; doi:10.1074/jbc.M504698200 [Abstract] [Full Text] [PDF]

Kris T. Huang, Agnes Keszler, Neil Patel, Rakesh P. Patel, Mark T. Gladwin, Daniel B. Kim-Shapiro, and Neil Hogg: The Reaction between Nitrite and Deoxyhemoglobin: REASSESSMENT OF REACTION KINETICS AND STOICHIOMETRY
J. Biol. Chem. 2005 280: 31126-31131. First Published on April 18, 2005; doi:10.1074/jbc.M501496200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Christine Schwimmer, Linnka Lefebvre-Legendre, Malgorzata Rak, Anne Devin, Piotr P. Slonimski, Jean-Paul di Rago, and Michel Rigoulet: Increasing Mitochondrial Substrate-level Phosphorylation Can Rescue Respiratory Growth of an ATP Synthase-deficient Yeast
J. Biol. Chem. 2005 280: 30751-30759. First Published on June 23, 2005; doi:10.1074/jbc.M501831200 [Abstract] [Full Text] [PDF]

Tamara Milakovic and Gail V. W. Johnson: Mitochondrial Respiration and ATP Production Are Significantly Impaired in Striatal Cells Expressing Mutant Huntingtin
J. Biol. Chem. 2005 280: 30773-30782. First Published on June 27, 2005; doi:10.1074/jbc.M504749200 [Abstract] [Full Text] [PDF]

Tomas Morosinotto, Matteo Ballottari, Frank Klimmek, Stefan Jansson, and Roberto Bassi: The Association of the Antenna System to Photosystem I in Higher Plants: COOPERATIVE INTERACTIONS STABILIZE THE SUPRAMOLECULAR COMPLEX AND ENHANCE RED-SHIFTED SPECTRAL FORMS
J. Biol. Chem. 2005 280: 31050-31058. First Published on June 27, 2005; doi:10.1074/jbc.M502935200 [Abstract] [Full Text] [PDF]

Md. Abdul Jalil, Laila Begum, Laura Contreras, Beatriz Pardo, Mikio Iijima, Meng Xian Li, Milagros Ramos, Patricia Marmol, Masahisa Horiuchi, Kyoko Shimotsu, Shiro Nakagawa, Akiko Okubo, Munefumi Sameshima, Yasushi Isashiki, Araceli del Arco, Keiko Kobayashi, Jorgina Satrústegui, and Takeyori Saheki: Reduced N-Acetylaspartate Levels in Mice Lacking Aralar, a Brain- and Muscle-type Mitochondrial Aspartate-glutamate Carrier
J. Biol. Chem. 2005 280: 31333-31339. First Published on June 29, 2005; doi:10.1074/jbc.M505286200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Svetlana A. Kuznetsova, Anthony J. Day, David J. Mahoney, Marilyn S. Rugg, Deane F. Mosher, and David D. Roberts: The N-terminal Module of Thrombospondin-1 Interacts with the Link Domain of TSG-6 and Enhances Its Covalent Association with the Heavy Chains of Inter- ${alpha}$ -trypsin Inhibitor
J. Biol. Chem. 2005 280: 30899-30908. First Published on July 8, 2005; doi:10.1074/jbc.M500701200 [Abstract] [Full Text] [PDF]

Natalia Nieto and Arthur I. Cederbaum: S-Adenosylmethionine Blocks Collagen I Production by Preventing Transforming Growth Factor- ${beta}$ Induction of the COL1A2 Promoter
J. Biol. Chem. 2005 280: 30963-30974. First Published on June 27, 2005; doi:10.1074/jbc.M503569200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Rama S. Kota, Chilakamarti V. Ramana, Fatima A. Tenorio, Richard I. Enelow, and John C. Rutledge: Differential Effects of Lipoprotein Lipase on Tumor Necrosis Factor- ${alpha}$ and Interferon- ${gamma}$ -mediated Gene Expression in Human Endothelial Cells
J. Biol. Chem. 2005 280: 31076-31084. First Published on July 1, 2005; doi:10.1074/jbc.M412189200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Markus Rapedius, Malle Soom, Ekaterina Shumilina, Dirk Schulze, Roland Schönherr, Cornelia Kirsch, Florian Lang, Stephen J. Tucker, and Thomas Baukrowitz: Long Chain CoA Esters as Competitive Antagonists of Phosphatidylinositol 4,5-Bisphosphate Activation in Kir Channels
J. Biol. Chem. 2005 280: 30760-30767. First Published on June 24, 2005; doi:10.1074/jbc.M503503200 [Abstract] [Full Text] [PDF]

Benito Ordaz, Jisen Tang, Rui Xiao, Alfonso Salgado, Alicia Sampieri, Michael X. Zhu, and Luis Vaca: Calmodulin and Calcium Interplay in the Modulation of TRPC5 Channel Activity: IDENTIFICATION OF A NOVEL C-TERMINAL DOMAIN FOR CALCIUM/CALMODULIN-MEDIATED FACILITATION
J. Biol. Chem. 2005 280: 30788-30796. First Published on June 29, 2005; doi:10.1074/jbc.M504745200 [Abstract] [Full Text] [PDF]

Yuan-Wei Zhang and Gary Rudnick: Cysteine-scanning Mutagenesis of Serotonin Transporter Intracellular Loop 2 Suggests an ${alpha}$ -Helical Conformation
J. Biol. Chem. 2005 280: 30807-30813. First Published on July 1, 2005; doi:10.1074/jbc.M504087200 [Abstract] [Full Text] [PDF]

Sergey I. Zakharov, John P. Morrow, Guoxia Liu, Lin Yang, and Steven O. Marx: Activation of the BK (SLO1) Potassium Channel by Mallotoxin
J. Biol. Chem. 2005 280: 30882-30887. First Published on July 5, 2005; doi:10.1074/jbc.M505302200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tomoyuki Suzuki, Kaori Ishihara, Hitoshi Migaki, Kengo Ishihara, Masaya Nagao, Yuko Yamaguchi-Iwai, and Taiho Kambe: Two Different Zinc Transport Complexes of Cation Diffusion Facilitator Proteins Localized in the Secretory Pathway Operate to Activate Alkaline Phosphatases in Vertebrate Cells
J. Biol. Chem. 2005 280: 30956-30962. First Published on July 1, 2005; doi:10.1074/jbc.M506902200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xinhong Pei, Xiuli An, Xinhua Guo, Michal Tarnawski, Ross Coppel, and Narla Mohandas: Structural and Functional Studies of Interaction between Plasmodium falciparum Knob-associated Histidine-rich Protein (KAHRP) and Erythrocyte Spectrin
J. Biol. Chem. 2005 280: 31166-31171. First Published on July 8, 2005; doi:10.1074/jbc.M505298200 [Abstract] [Full Text] [PDF]

Jana Friedemann, Frank Grosse, and Suisheng Zhang: Nuclear DNA Helicase II (RNA Helicase A) Interacts with Werner Syndrome Helicase and Stimulates Its Exonuclease Activity
J. Biol. Chem. 2005 280: 31303-31313. First Published on July 1, 2005; doi:10.1074/jbc.M503882200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Stephan Wullschleger, Robbie Loewith, Wolfgang Oppliger, and Michael N. Hall: Molecular Organization of Target of Rapamycin Complex 2
J. Biol. Chem. 2005 280: 30697-30704. First Published on July 7, 2005; doi:10.1074/jbc.M505553200 [Abstract] [Full Text] [PDF]

Catherine Vial and Richard J. Evans: Disruption of Lipid Rafts Inhibits P2X₁ Receptor-mediated Currents and Arterial Vasoconstriction
J. Biol. Chem. 2005 280: 30705-30711. First Published on July 8, 2005; doi:10.1074/jbc.M504256200 [Abstract] [Full Text] [PDF]

Gareth Brady, Louise Boggan, Andrew Bowie, and Luke A. J. O'Neill: Schlafen-1 Causes a Cell Cycle Arrest by Inhibiting Induction of Cyclin D1
J. Biol. Chem. 2005 280: 30723-30734. First Published on June 9, 2005; doi:10.1074/jbc.M500435200 [Abstract] [Full Text] [PDF]

Justin H. Turner and John R. Raymond: Interaction of Calmodulin with the Serotonin 5-Hydroxytryptamine_2A Receptor: A PUTATIVE REGULATOR OF G PROTEIN COUPLING AND RECEPTOR PHOSPHORYLATION BY PROTEIN KINASE C
J. Biol. Chem. 2005 280: 30741-30750. First Published on June 21, 2005; doi:10.1074/jbc.M501696200 [Abstract] [Full Text] [PDF]

Rajeswara Rao Arasada and Graham Carpenter: Secretase-dependent Tyrosine Phosphorylation of Mdm2 by the ErbB-4 Intracellular Domain Fragment
J. Biol. Chem. 2005 280: 30783-30787. First Published on June 27, 2005; doi:10.1074/jbc.M506057200 [Abstract] [Full Text] [PDF]

John J. Enyeart, Sanjay J. Danthi, Haiyan Liu, and Judith A. Enyeart: Angiotensin II Inhibits bTREK-1 K⁺ Channels in Adrenocortical Cells by Separate Ca²⁺- and ATP Hydrolysis-dependent Mechanisms
J. Biol. Chem. 2005 280: 30814-30828. First Published on July 1, 2005; doi:10.1074/jbc.M504283200 [Abstract] [Full Text] [PDF]

Matthias Christen, Beat Christen, Marc Folcher, Alexandra Schauerte, and Urs Jenal: Identification and Characterization of a Cyclic di-GMP-specific Phosphodiesterase and Its Allosteric Control by GTP
J. Biol. Chem. 2005 280: 30829-30837. First Published on July 1, 2005; doi:10.1074/jbc.M504429200 [Abstract] [Full Text] [PDF]

Geraldine Maloney, Martina Schröder, and Andrew G. Bowie: Vaccinia Virus Protein A52R Activates p38 Mitogen-activated Protein Kinase and Potentiates Lipopolysaccharide-induced Interleukin-10
J. Biol. Chem. 2005 280: 30838-30844. First Published on July 5, 2005; doi:10.1074/jbc.M501917200 [Abstract] [Full Text] [PDF]

Debbie Willoughby, Nanako Masada, Andrew J. Crossthwaite, Antonio Ciruela, and Dermot M. F. Cooper: Localized Na⁺/H⁺ Exchanger 1 Expression Protects Ca²⁺-regulated Adenylyl Cyclases from Changes in Intracellular pH
J. Biol. Chem. 2005 280: 30864-30872. First Published on July 7, 2005; doi:10.1074/jbc.M414355200 [Abstract] [Full Text] [PDF]

Heike Keilhack, Frank S. David, Malcolm McGregor, Lewis C. Cantley, and Benjamin G. Neel: Diverse Biochemical Properties of Shp2 Mutants: IMPLICATIONS FOR DISEASE PHENOTYPES
J. Biol. Chem. 2005 280: 30984-30993. First Published on June 29, 2005; doi:10.1074/jbc.M504699200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Peter J. Reddig, Dong Xu, and Rudy L. Juliano: Regulation of p21-activated Kinase-independent Rac1 Signal Transduction by Nischarin
J. Biol. Chem. 2005 280: 30994-31002. First Published on July 7, 2005; doi:10.1074/jbc.M502546200 [Abstract] [Full Text] [PDF]

Jongyun Heo and Sharon L. Campbell: Mechanism of Redox-mediated Guanine Nucleotide Exchange on Redox-active Rho GTPases
J. Biol. Chem. 2005 280: 31003-31010. First Published on June 30, 2005; doi:10.1074/jbc.M504768200 [Abstract] [Full Text] [PDF]

Lori L. Anderson, Garland R. Marshall, Evan Crocker, Steven O. Smith, and Thomas J. Baranski: Motion of Carboxyl Terminus of G ${alpha}$ Is Restricted upon G Protein Activation: A SOLUTION NMR STUDY USING SEMISYNTHETIC G ${alpha}$ SUBUNITS
J. Biol. Chem. 2005 280: 31019-31026. First Published on June 27, 2005; doi:10.1074/jbc.M503690200 [Abstract] [Full Text] [PDF]

Jiao-Hui Wu, Robi Goswami, Luke K. Kim, William E. Miller, Karsten Peppel, and Neil J. Freedman: The Platelet-derived Growth Factor Receptor- ${beta}$ Phosphorylates and Activates G Protein-coupled Receptor Kinase-2: A MECHANISM FOR FEEDBACK INHIBITION
J. Biol. Chem. 2005 280: 31027-31035. First Published on July 1, 2005; doi:10.1074/jbc.M501473200 [Abstract] [Full Text] [PDF]

Brian P. Head, Hemal H. Patel, David M. Roth, N. Chin Lai, Ingrid R. Niesman, Marilyn G. Farquhar, and Paul A. Insel: G-protein-coupled Receptor Signaling Components Localize in Both Sarcolemmal and Intracellular Caveolin-3-associated Microdomains in Adult Cardiac Myocytes
J. Biol. Chem. 2005 280: 31036-31044. First Published on June 16, 2005; doi:10.1074/jbc.M502540200 [Abstract] [Full Text] [PDF]

Ken-ichiro Tanaka, Wataru Tomisato, Tatsuya Hoshino, Tomoaki Ishihara, Takushi Namba, Mayuko Aburaya, Takashi Katsu, Keitarou Suzuki, Shinji Tsutsumi, and Tohru Mizushima: Involvement of Intracellular Ca²⁺ Levels in Nonsteroidal Anti-inflammatory Drug-induced Apoptosis
J. Biol. Chem. 2005 280: 31059-31067. First Published on June 29, 2005; doi:10.1074/jbc.M502956200 [Abstract] [Full Text] [PDF]

Margaret H. Magdesian, Arthur A. Nery, A. Henrique B. Martins, Maria Aparecida Juliano, Luiz Juliano, Henning Ulrich, and Sérgio T. Ferreira: Peptide Blockers of the Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Amyloid ${beta}$
J. Biol. Chem. 2005 280: 31085-31090. First Published on June 29, 2005; doi:10.1074/jbc.M502406200 [Abstract] [Full Text] [PDF]

Ramesh M. Ray, Sujoy Bhattacharya, and Leonard R. Johnson: Protein Phosphatase 2A Regulates Apoptosis in Intestinal Epithelial Cells
J. Biol. Chem. 2005 280: 31091-31100. First Published on July 1, 2005; doi:10.1074/jbc.M503041200 [Abstract] [Full Text] [PDF]

Andrea D. Basso, Asra Mirza, Gongjie Liu, Brian J. Long, W. Robert Bishop, and Paul Kirschmeier: The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling: ROLE IN FTI ENHANCEMENT OF TAXANE AND TAMOXIFEN ANTI-TUMOR ACTIVITY
J. Biol. Chem. 2005 280: 31101-31108. First Published on July 8, 2005; doi:10.1074/jbc.M503763200 [Abstract] [Full Text] [PDF]

Natalia Cheshenko, Wen Liu, Lisa M. Satlin, and Betsy C. Herold: Focal Adhesion Kinase Plays a Pivotal Role in Herpes Simplex Virus Entry
J. Biol. Chem. 2005 280: 31116-31125. First Published on July 1, 2005; doi:10.1074/jbc.M503518200 [Abstract] [Full Text] [PDF]

Rebecca A. Deaton, Chang Su, Thomas G. Valencia, and Stephen R. Grant: Transforming Growth Factor- ${beta}$ 1-induced Expression of Smooth Muscle Marker Genes Involves Activation of PKN and p38 MAPK
J. Biol. Chem. 2005 280: 31172-31181. First Published on June 26, 2005; doi:10.1074/jbc.M504774200 [Abstract] [Full Text] [PDF]

Stéphane Bach, Marie Knockaert, Jens Reinhardt, Olivier Lozach, Sophie Schmitt, Blandine Baratte, Marcel Koken, Stephen P. Coburn, Lin Tang, Tao Jiang, Dong-cai Liang, Hervé Galons, Jean-Francois Dierick, Lorenzo A. Pinna, Flavio Meggio, Frank Totzke, Christoph Schächtele, Andrea S. Lerman, Amancio Carnero, Yongqin Wan, Nathanael Gray, and Laurent Meijer: Roscovitine Targets, Protein Kinases and Pyridoxal Kinase
J. Biol. Chem. 2005 280: 31208-31219. First Published on June 23, 2005; doi:10.1074/jbc.M500806200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rohit Seth, Cheng Yang, Varsha Kaushal, Sudhir V. Shah, and Gur P. Kaushal: p53-dependent Caspase-2 Activation in Mitochondrial Release of Apoptosis-inducing Factor and Its Role in Renal Tubular Epithelial Cell Injury
J. Biol. Chem. 2005 280: 31230-31239. First Published on June 27, 2005; doi:10.1074/jbc.M503305200 [Abstract] [Full Text] [PDF]

Xiaohong Zhou, Feng Li, Li Kong, Hiroshi Tomita, Chao Li, and Wei Cao: Involvement of Inflammation, Degradation, and Apoptosis in a Mouse Model of Glaucoma
J. Biol. Chem. 2005 280: 31240-31248. First Published on June 28, 2005; doi:10.1074/jbc.M502641200 [Abstract] [Full Text] [PDF] [Summary]

Min Ye, Fumi Shima, Shin Muraoka, Jingling Liao, Hidetsugu Okamoto, Masaki Yamamoto, Atsuo Tamura, Naoto Yagi, Tatzuo Ueki, and Tohru Kataoka: Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
J. Biol. Chem. 2005 280: 31267-31275. First Published on June 30, 2005; doi:10.1074/jbc.M505503200 [Abstract] [Full Text] [PDF]

Luis R. Landa, Jr., Mark Harbeck, Kelly Kaihara, Oleg Chepurny, Kajorn Kitiphongspattana, Oliver Graf, Viacheslav O. Nikolaev, Martin J. Lohse, George G. Holz, and Michael W. Roe: Interplay of Ca²⁺ and cAMP Signaling in the Insulin-secreting MIN6 ${beta}$ -Cell Line
J. Biol. Chem. 2005 280: 31294-31302. First Published on June 29, 2005; doi:10.1074/jbc.M505657200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Basis Of Cell and Developmental Biology:

Jooyoung Jung, Tae-gyun Kim, Gary E. Lyons, Hyeong-Reh C. Kim, and Youngsook Lee: Jumonji Regulates Cardiomyocyte Proliferation via Interaction with Retinoblastoma Protein
J. Biol. Chem. 2005 280: 30916-30923. First Published on May 3, 2005; doi:10.1074/jbc.M414482200 [Abstract] [Full Text] [PDF]

Naama Rave-Harel, Nichol L. G. Miller, Marjory L. Givens, and Pamela L. Mellon: The Groucho-related Gene Family Regulates the Gonadotropin-releasing Hormone Gene through Interaction with the Homeodomain Proteins MSX1 and OCT1
J. Biol. Chem. 2005 280: 30975-30983. First Published on July 7, 2005; doi:10.1074/jbc.M502315200 [Abstract] [Full Text] [PDF]

Michail Nomikos, Lynda M. Blayney, Mark G. Larman, Karen Campbell, Andreas Rossbach, Christopher M. Saunders, Karl Swann, and F. Anthony Lai: Role of Phospholipase C- ${zeta}$ Domains in Ca²⁺-dependent Phosphatidylinositol 4,5-Bisphosphate Hydrolysis and Cytoplasmic Ca²⁺ Oscillations
J. Biol. Chem. 2005 280: 31011-31018. First Published on July 6, 2005; doi:10.1074/jbc.M500629200 [Abstract] [Full Text] [PDF]

Roderick P. Regala, Capella Weems, Lee Jamieson, John A. Copland, E. Aubrey Thompson, and Alan P. Fields: Atypical Protein Kinase C ${iota}$ Plays a Critical Role in Human Lung Cancer Cell Growth and Tumorigenicity
J. Biol. Chem. 2005 280: 31109-31115. First Published on July 1, 2005; doi:10.1074/jbc.M505402200 [Abstract] [Full Text] [PDF]

Ling Yang, Sara G. Carlson, Denise McBurney, and Walter E. Horton, Jr.: Multiple Signals Induce Endoplasmic Reticulum Stress in Both Primary and Immortalized Chondrocytes Resulting in Loss of Differentiation, Impaired Cell Growth, and Apoptosis
J. Biol. Chem. 2005 280: 31156-31165. First Published on July 5, 2005; doi:10.1074/jbc.M501069200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Derek P. Nolan, David G. Jackson, Mary J. Biggs, Elaine D. Brabazon, Annette Pays, François Van Laethem, Françoise Paturiaux-Hanocq, John F. Elliott, H. Paul Voorheis, and Etienne Pays: Characterization of a novel alanine-rich protein located in surface microdomains in Trypanosoma brucei. Vol. 275 (2000) 4072-4080
J. Biol. Chem. 2005 280: 31340. [Full Text] [PDF]

Chi-hwa Wu and Roel Nusse: Ligand receptor interactions in the Wnt signaling pathway in Drosophila. Vol. 277 (2002) 41762-41769
J. Biol. Chem. 2005 280: 31340-a. [Full Text] [PDF]