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Table of Contents: Sep 9 2005; 280 (36)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption] [Table of Contents (PDF)] [Masthead (PDF)]
       Papers Of The Week
       Classics
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Papers Of The Week:

Water, Water Everywhere
J. Biol. Chem. 2005 280: e99942. [Full Text] [PDF]  


Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
The Sequences of Pea and Calf Thymus Histone H4: James Bonner and Emil Smith
Calf and Pea Histone IV. III. COMPLETE AMINO ACID SEQUENCE OF PEA SEEDLING HISTONE IV; COMPARISON WITH THE HOMOLOGOUS CALF THYMUS HISTONE (Robert J. DeLange, Douglas M. Fambrough, Emil L. Smith, and James Bonner J. Biol. Chem. 244, 5669-5679)
J. Biol. Chem. 2005 280: e33. [Full Text]  


DNA: Replication, Repair, and Recombination:

Sherine S. L. Chan, Matthew J. Longley, and William C. Copeland
The Common A467T Mutation in the Human Mitochondrial DNA Polymerase (POLG) Compromises Catalytic Efficiency and Interaction with the Accessory Subunit
J. Biol. Chem. 2005 280: 31341-31346. First Published on July 16, 2005; doi:10.1074/jbc.M506762200 [Abstract] [Full Text] [PDF]  

Li Liang, Li Deng, Yanping Chen, Gloria C. Li, Changshun Shao, and Jay A. Tischfield
Modulation of DNA End Joining by Nuclear Proteins
J. Biol. Chem. 2005 280: 31442-31449. First Published on July 11, 2005; doi:10.1074/jbc.M503776200 [Abstract] [Full Text] [PDF]  

S. Dean Rider, Jr., Xiaomin Cai, William J. Sullivan, Jr., Aaron T. Smith, Jay Radke, Michael White, and Guan Zhu
The Protozoan Parasite Cryptosporidium parvum Possesses Two Functionally and Evolutionarily Divergent Replication Protein A Large Subunits
J. Biol. Chem. 2005 280: 31460-31469. First Published on July 11, 2005; doi:10.1074/jbc.M504466200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Elena K. Braithwaite, Padmini S. Kedar, Li Lan, Yaroslava Y. Polosina, Kenjiro Asagoshi, Vladimir P. Poltoratsky, Julie K. Horton, Holly Miller, George W. Teebor, Akira Yasui, and Samuel H. Wilson
DNA Polymerase {lambda} Protects Mouse Fibroblasts against Oxidative DNA Damage and Is Recruited to Sites of DNA Damage/Repair
J. Biol. Chem. 2005 280: 31641-31647. First Published on July 7, 2005; doi:10.1074/jbc.C500256200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Daniel P. Morris, Gregory A. Michelotti, and Debra A. Schwinn
Evidence That Phosphorylation of the RNA Polymerase II Carboxyl-terminal Repeats Is Similar in Yeast and Humans
J. Biol. Chem. 2005 280: 31368-31377. First Published on July 12, 2005; doi:10.1074/jbc.M501546200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Madoka Koyanagi, Aurelie Baguet, Joost Martens, Raphael Margueron, Thomas Jenuwein, and Mark Bix
EZH2 and Histone 3 Trimethyl Lysine 27 Associated with Il4 and Il13 Gene Silencing in TH1 Cells
J. Biol. Chem. 2005 280: 31470-31477. First Published on July 11, 2005; doi:10.1074/jbc.M504766200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Detlef Vullhorst and Andres Buonanno
Multiple GTF2I-like Repeats of General Transcription Factor 3 Exhibit DNA Binding Properties: EVIDENCE FOR A COMMON ORIGIN AS A SEQUENCE-SPECIFIC DNA INTERACTION MODULE
J. Biol. Chem. 2005 280: 31722-31731. First Published on June 28, 2005; doi:10.1074/jbc.M500593200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Florence Y. Lee, Heidi R. Kast-Woelbern, Jenny Chang, Guizhen Luo, Stacey A. Jones, Michael C. Fishbein, and Peter A. Edwards
{alpha}-Crystallin Is a Target Gene of the Farnesoid X-activated Receptor in Human Livers
J. Biol. Chem. 2005 280: 31792-31800. First Published on July 11, 2005; doi:10.1074/jbc.M503182200 [Abstract] [Full Text] [PDF]  

Maria Assunta Bevilacqua, Barbara Iovine, Nicola Zambrano, Chiara D'Ambrosio, Andrea Scaloni, Tommaso Russo, and Filiberto Cimino
Fibromodulin Gene Transcription Is Induced by Ultraviolet Irradiation, and Its Regulation Is Impaired in Senescent Human Fibroblasts
J. Biol. Chem. 2005 280: 31809-31817. First Published on July 6, 2005; doi:10.1074/jbc.M414677200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


RNA: Structure, Metabolism, and Catalysis:

Petr V. Sergiev, Dmitry V. Lesnyak, Dmitry E. Burakovsky, Sergey V. Kiparisov, Andrei A. Leonov, Alexey A. Bogdanov, Richard Brimacombe, and Olga A. Dontsova
Alteration in Location of a Conserved GTPase-associated Center of the Ribosome Induced by Mutagenesis Influences the Structure of Peptidyltransferase Center and Activity of Elongation Factor G
J. Biol. Chem. 2005 280: 31882-31889. First Published on July 12, 2005; doi:10.1074/jbc.M505670200 [Abstract] [Full Text] [PDF]  

Irina Tretyakova, Andrei S. Zolotukhin, Wei Tan, Jenifer Bear, Friedrich Propst, Gordon Ruthel, and Barbara K. Felber
Nuclear Export Factor Family Protein Participates in Cytoplasmic mRNA Trafficking
J. Biol. Chem. 2005 280: 31981-31990. First Published on July 12, 2005; doi:10.1074/jbc.M502736200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Taiji Kimura, Yasuhiro Hosoda, Yoshimi Sato, Yukiko Kitamura, Takezo Ikeda, Tomohisa Horibe, and Masakazu Kikuchi
Interactions among Yeast Protein-Disulfide Isomerase Proteins and Endoplasmic Reticulum Chaperone Proteins Influence Their Activities
J. Biol. Chem. 2005 280: 31438-31441. First Published on July 7, 2005; doi:10.1074/jbc.M503377200 [Abstract] [Full Text] [PDF]  

Fumika Sakaue, Taro Saito, Yutaka Sato, Akiko Asada, Koichi Ishiguro, Masato Hasegawa, and Shin-ichi Hisanaga
Phosphorylation of FTDP-17 Mutant tau by Cyclin-dependent Kinase 5 Complexed with p35, p25, or p39
J. Biol. Chem. 2005 280: 31522-31529. First Published on July 1, 2005; doi:10.1074/jbc.M504792200 [Abstract] [Full Text] [PDF]  

Jun Onodera and Yoshinori Ohsumi
Autophagy Is Required for Maintenance of Amino Acid Levels and Protein Synthesis under Nitrogen Starvation
J. Biol. Chem. 2005 280: 31582-31586. First Published on July 15, 2005; doi:10.1074/jbc.M506736200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Roman Sobotka, Josef Komenda, Ladislav Bumba, and Martin Tichy
Photosystem II Assembly in CP47 Mutant of Synechocystis sp. PCC 6803 Is Dependent on the Level of Chlorophyll Precursors Regulated by Ferrochelatase
J. Biol. Chem. 2005 280: 31595-31602. First Published on July 18, 2005; doi:10.1074/jbc.M505976200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Nadeem Wajih, Susan M. Hutson, John Owen, and Reidar Wallin
Increased Production of Functional Recombinant Human Clotting Factor IX by Baby Hamster Kidney Cells Engineered to Overexpress VKORC1, the Vitamin K 2,3-Epoxide-reducing Enzyme of the Vitamin K Cycle
J. Biol. Chem. 2005 280: 31603-31607. First Published on July 19, 2005; doi:10.1074/jbc.M505373200 [Abstract] [Full Text] [PDF]  

Nina Lüdemann, Albrecht Clement, Volkmar H. Hans, Julia Leschik, Christian Behl, and Roland Brandt
O-Glycosylation of the Tail Domain of Neurofilament Protein M in Human Neurons and in Spinal Cord Tissue of a Rat Model of Amyotrophic Lateral Sclerosis (ALS)
J. Biol. Chem. 2005 280: 31648-31658. First Published on July 8, 2005; doi:10.1074/jbc.M504395200 [Abstract] [Full Text] [PDF]  

Brent L. Kelly, Robert Vassar, and Adriana Ferreira
{beta}-Amyloid-induced Dynamin 1 Depletion in Hippocampal Neurons: A POTENTIAL MECHANISM FOR EARLY COGNITIVE DECLINE IN ALZHEIMER DISEASE
J. Biol. Chem. 2005 280: 31746-31753. First Published on July 7, 2005; doi:10.1074/jbc.M503259200 [Abstract] [Full Text] [PDF]  

Fei Hong, Konjeti R. Sekhar, Michael L. Freeman, and Daniel C. Liebler
Specific Patterns of Electrophile Adduction Trigger Keap1 Ubiquitination and Nrf2 Activation
J. Biol. Chem. 2005 280: 31768-31775. First Published on June 28, 2005; doi:10.1074/jbc.M503346200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Sarah J. Shoesmith Berke, Yaohui Chai, Ginger L. Marrs, Hsiang Wen, and Henry L. Paulson
Defining the Role of Ubiquitin-interacting Motifs in the Polyglutamine Disease Protein, Ataxin-3
J. Biol. Chem. 2005 280: 32026-32034. First Published on July 21, 2005; doi:10.1074/jbc.M506084200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Nadine Merkley, Kathryn R. Barber, and Gary S. Shaw
Ubiquitin Manipulation by an E2 Conjugating Enzyme Using a Novel Covalent Intermediate
J. Biol. Chem. 2005 280: 31732-31738. First Published on July 12, 2005; doi:10.1074/jbc.M505205200 [Abstract] [Full Text] [PDF]  

Peili Gu, Daniel H. Morgan, Minawar Sattar, Xueping Xu, Ryan Wagner, Michele Raviscioni, Olivier Lichtarge, and Austin J. Cooney
Evolutionary Trace-based Peptides Identify a Novel Asymmetric Interaction That Mediates Oligomerization in Nuclear Receptors
J. Biol. Chem. 2005 280: 31818-31829. First Published on July 1, 2005; doi:10.1074/jbc.M501924200 [Abstract] [Full Text] [PDF]  

Adriano Sebollela, Thiago C. Cagliari, Gabriel S. C. S. Limaverde, Alex Chapeaurouge, Marcos H. F. Sorgine, Tatiana Coelho-Sampaio, Carlos H. I. Ramos, and Sérgio T. Ferreira
Heparin-binding Sites in Granulocyte-Macrophage Colony-stimulating Factor: LOCALIZATION AND REGULATION BY HISTIDINE IONIZATION
J. Biol. Chem. 2005 280: 31949-31956. First Published on July 15, 2005; doi:10.1074/jbc.M505314200 [Abstract] [Full Text] [PDF]  

Jason G. S. Ho, Pavel I. Kitov, Eugenia Paszkiewicz, Joanna Sadowska, David R. Bundle, and Kenneth K.-S. Ng
Ligand-assisted Aggregation of Proteins: DIMERIZATION OF SERUM AMYLOID P COMPONENT BY BIVALENT LIGANDS
J. Biol. Chem. 2005 280: 31999-32008. First Published on July 20, 2005; doi:10.1074/jbc.M504403200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Enzyme Catalysis and Regulation:

Edward D. Högestätt, Bo A. G. Jönsson, Anna Ermund, David A. Andersson, Henrik Björk, Jessica P. Alexander, Benjamin F. Cravatt, Allan I. Basbaum, and Peter M. Zygmunt
Conversion of Acetaminophen to the Bioactive N-Acylphenolamine AM404 via Fatty Acid Amide Hydrolase-dependent Arachidonic Acid Conjugation in the Nervous System
J. Biol. Chem. 2005 280: 31405-31412. First Published on June 29, 2005; doi:10.1074/jbc.M501489200 [Abstract] [Full Text] [PDF]  

Babak Andi, Ann H. West, and Paul F. Cook
Regulatory Mechanism of Histidine-tagged Homocitrate Synthase from Saccharomyces cerevisiae: I. KINETIC STUDIES
J. Biol. Chem. 2005 280: 31624-31632. First Published on May 16, 2005; doi:10.1074/jbc.M502846200 [Abstract] [Full Text] [PDF]  

Babak Andi and Paul F. Cook
Regulatory Mechanism of Histidine-tagged Homocitrate Synthase from Saccharomyces cerevisiae: II. THEORY
J. Biol. Chem. 2005 280: 31633-31640. First Published on May 16, 2005; doi:10.1074/jbc.M502847200 [Abstract] [Full Text] [PDF]  

Shingo Nagano and Thomas L. Poulos
Crystallographic Study on the Dioxygen Complex of Wild-type and Mutant Cytochrome P450cam: IMPLICATIONS FOR THE DIOXYGEN ACTIVATION MECHANISM
J. Biol. Chem. 2005 280: 31659-31663. First Published on June 30, 2005; doi:10.1074/jbc.M505261200 [Abstract] [Full Text] [PDF] [Summary]  

Cassie Aldridge and Simon Geir Møller
The Plastid Division Protein AtMinD1 Is a Ca2+-ATPase Stimulated by AtMinE1
J. Biol. Chem. 2005 280: 31673-31678. First Published on July 13, 2005; doi:10.1074/jbc.M505126200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yan Weng, Concetta C. DiRusso, Andrew A. Reilly, Paul N. Black, and Xinxin Ding
Hepatic Gene Expression Changes in Mouse Models with Liver-specific Deletion or Global Suppression of the NADPH-Cytochrome P450 Reductase Gene: MECHANISTIC IMPLICATIONS FOR THE REGULATION OF MICROSOMAL CYTOCHROME P450 AND THE FATTY LIVER PHENOTYPE
J. Biol. Chem. 2005 280: 31686-31698. First Published on July 8, 2005; doi:10.1074/jbc.M504447200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Clemens Steegborn, Tatiana N. Litvin, Kenneth C. Hess, Austin B. Capper, Ronald Taussig, Jochen Buck, Lonny R. Levin, and Hao Wu
A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of Its Complex with Catechol Estrogen
J. Biol. Chem. 2005 280: 31754-31759. First Published on July 7, 2005; doi:10.1074/jbc.M507144200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Pakorn Winayanuwattikun and Albert J. Ketterman
An Electron-sharing Network Involved in the Catalytic Mechanism Is Functionally Conserved in Different Glutathione Transferase Classes
J. Biol. Chem. 2005 280: 31776-31782. First Published on July 12, 2005; doi:10.1074/jbc.M502612200 [Abstract] [Full Text] [PDF]  

Magdalena M. Kacprzak, Manuel E. Than, Luiz Juliano, Maria A. Juliano, Wolfram Bode, and Iris Lindberg
Mutations of the PC2 Substrate Binding Pocket Alter Enzyme Specificity
J. Biol. Chem. 2005 280: 31850-31858. First Published on July 7, 2005; doi:10.1074/jbc.M505567200 [Abstract] [Full Text] [PDF]  

Tsukasa Kawahara, Darren Ritsick, Guangjie Cheng, and J. David Lambeth
Point Mutations in the Proline-rich Region of p22phox Are Dominant Inhibitors of Nox1- and Nox2-dependent Reactive Oxygen Generation
J. Biol. Chem. 2005 280: 31859-31869. First Published on June 30, 2005; doi:10.1074/jbc.M501882200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Madhavan R. Buddha and Brian R. Crane
Structures of Tryptophanyl-tRNA Synthetase II from Deinococcus radiodurans Bound to ATP and Tryptophan: INSIGHT INTO SUBUNIT COOPERATIVITY AND DOMAIN MOTIONS LINKED TO CATALYSIS
J. Biol. Chem. 2005 280: 31965-31973. First Published on July 5, 2005; doi:10.1074/jbc.M501568200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Alisha Johnson, Peter Gin, Beth N. Marbois, Edward J. Hsieh, Mian Wu, Mario H. Barros, Catherine F. Clarke, and Alexander Tzagoloff
COQ9, a New Gene Required for the Biosynthesis of Coenzyme Q in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 31397-31404. First Published on July 18, 2005; doi:10.1074/jbc.M503277200 [Abstract] [Full Text] [PDF]  

Christophe Graveleau, Vlad G. Zaha, Arash Mohajer, Ronadip R. Banerjee, Nicole Dudley-Rucker, Claire M. Steppan, Michael W. Rajala, Philipp E. Scherer, Rexford S. Ahima, Mitchell A. Lazar, and E. Dale Abel
Mouse and Human Resistins Impair Glucose Transport in Primary Mouse Cardiomyocytes, and Oligomerization Is Required for This Biological Action
J. Biol. Chem. 2005 280: 31679-31685. First Published on June 27, 2005; doi:10.1074/jbc.M504008200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Glycobiology and Extracellular Matrices:

Jeremy Moore, Simon E. S. Bailey, Zineb Benmechernene, Christos Tzitzilonis, Natalie J. E. Griffiths, Mumtaz Virji, and Jeremy P. Derrick
Recognition of Saccharides by the OpcA, OpaD, and OpaB Outer Membrane Proteins from Neisseria meningitidis
J. Biol. Chem. 2005 280: 31489-31497. First Published on July 8, 2005; doi:10.1074/jbc.M506354200 [Abstract] [Full Text] [PDF]  

Satoko Ashikari-Hada, Hiroko Habuchi, Yutaka Kariya, and Koji Kimata
Heparin Regulates Vascular Endothelial Growth Factor165-dependent Mitogenic Activity, Tube Formation, and Its Receptor Phosphorylation of Human Endothelial Cells: COMPARISON OF THE EFFECTS OF HEPARIN AND MODIFIED HEPARINS
J. Biol. Chem. 2005 280: 31508-31515. First Published on July 15, 2005; doi:10.1074/jbc.M414581200 [Abstract] [Full Text] [PDF]  

Kirsi Rilla, Hanna Siiskonen, Andrew P. Spicer, Juha M. T. Hyttinen, Markku I. Tammi, and Raija H. Tammi
Plasma Membrane Residence of Hyaluronan Synthase Is Coupled to Its Enzymatic Activity
J. Biol. Chem. 2005 280: 31890-31897. First Published on July 13, 2005; doi:10.1074/jbc.M504736200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Lipids and Lipoproteins:

Shin-ichiro Kubo, Venu M. Nemani, Robert J. Chalkley, Malcolm D. Anthony, Nobutaka Hattori, Yoshikuni Mizuno, Robert H. Edwards, and Doris L. Fortin
A Combinatorial Code for the Interaction of {alpha}-Synuclein with Membranes
J. Biol. Chem. 2005 280: 31664-31672. First Published on July 14, 2005; doi:10.1074/jbc.M504894200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Éric Durand, Gérard Michel, Romé Voulhoux, Julia Kürner, Alain Bernadac, and Alain Filloux
XcpX Controls Biogenesis of the Pseudomonas aeruginosa XcpT-containing Pseudopilus
J. Biol. Chem. 2005 280: 31378-31389. First Published on July 12, 2005; doi:10.1074/jbc.M505812200 [Abstract] [Full Text] [PDF]  

Tanja Bachhuber, Jens König, Thilo Voelcker, Bettina Mürle, Rainer Schreiber, and Karl Kunzelmann
Cl Interference with the Epithelial Na+ Channel ENaC
J. Biol. Chem. 2005 280: 31587-31594. First Published on July 18, 2005; doi:10.1074/jbc.M504347200 [Abstract] [Full Text] [PDF]  

Dejana Mokranjac, Martin Sichting, Dusan Popov-Celeketic, Annette Berg, Kai Hell, and Walter Neupert
The Import Motor of the Yeast Mitochondrial TIM23 Preprotein Translocase Contains Two Different J Proteins, Tim14 and Mdj2
J. Biol. Chem. 2005 280: 31608-31614. First Published on July 18, 2005; doi:10.1074/jbc.M502397200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Lei Chen, Junko Kurokawa, and Robert S. Kass
Phosphorylation of the A-kinase-anchoring Protein Yotiao Contributes to Protein Kinase A Regulation of a Heart Potassium Channel
J. Biol. Chem. 2005 280: 31347-31352. First Published on July 7, 2005; doi:10.1074/jbc.M505191200 [Abstract] [Full Text] [PDF]  

Ayse B. Celil and Phil G. Campbell
BMP-2 and Insulin-like Growth Factor-I Mediate Osterix (Osx) Expression in Human Mesenchymal Stem Cells via the MAPK and Protein Kinase D Signaling Pathways
J. Biol. Chem. 2005 280: 31353-31359. First Published on July 5, 2005; doi:10.1074/jbc.M503845200 [Abstract] [Full Text] [PDF]  

Hongxia Z. Imtiyaz, Yuhang Zhang, and Jianke Zhang
Structural Requirements for Signal-induced Target Binding of FADD Determined by Functional Reconstitution of FADD Deficiency
J. Biol. Chem. 2005 280: 31360-31367. First Published on July 11, 2005; doi:10.1074/jbc.M504138200 [Abstract] [Full Text] [PDF]  

Heather L. Ball and David Cortez
ATRIP Oligomerization Is Required for ATR-dependent Checkpoint Signaling
J. Biol. Chem. 2005 280: 31390-31396. First Published on July 15, 2005; doi:10.1074/jbc.M504961200 [Abstract] [Full Text] [PDF]  

Paul A. Nony, Sarah B. Kennett, Wayne C. Glasgow, Kenneth Olden, and John D. Roberts
15(S)-Lipoxygenase-2 Mediates Arachidonic Acid-stimulated Adhesion of Human Breast Carcinoma Cells through the Activation of TAK1, MKK6, and p38 MAPK
J. Biol. Chem. 2005 280: 31413-31419. First Published on July 6, 2005; doi:10.1074/jbc.M500418200 [Abstract] [Full Text] [PDF]  

Sujuan Cui, Xiaoqiang Guo, Fang Chang, Yanwei Cui, Ligeng Ma, Ying Sun, and Daye Sun
Apoplastic Calmodulin Receptor-like Binding Proteins in Suspension-cultured Cells of Arabidopsis thaliana
J. Biol. Chem. 2005 280: 31420-31427. First Published on July 6, 2005; doi:10.1074/jbc.M501349200 [Abstract] [Full Text] [PDF]  

Kiyokazu Inagaki, Hiroshi Kobayashi, Ryuji Yoshida, Yasufumi Kanada, Yoichi Fukuda, Tatsuo Yagyu, Toshiharu Kondo, Noriyuki Kurita, Takashi Kitanaka, Yoshihiko Yamada, Yoshiharu Sakamoto, Mika Suzuki, Naohiro Kanayama, and Toshihiko Terao
Suppression of Urokinase Expression and Invasion by a Soybean Kunitz Trypsin Inhibitor Are Mediated through Inhibition of Src-dependent Signaling Pathways
J. Biol. Chem. 2005 280: 31428-31437. First Published on July 7, 2005; doi:10.1074/jbc.M501406200 [Abstract] [Full Text] [PDF]  

Neesha Suvarna, Stephanie L. Borgland, Jun Wang, Khanhky Phamluong, Yves P. Auberson, Antonello Bonci, and Dorit Ron
Ethanol Alters Trafficking and Functional N-Methyl-D-aspartate Receptor NR2 Subunit Ratio via H-Ras
J. Biol. Chem. 2005 280: 31450-31459. First Published on July 11, 2005; doi:10.1074/jbc.M504120200 [Abstract] [Full Text] [PDF]  

Ulrike Sommer, Christine Schmid, Radoslaw M. Sobota, Ute Lehmann, Nigel J. Stevenson, James A. Johnston, Fred Schaper, Peter C. Heinrich, and Serge Haan
Mechanisms of SOCS3 Phosphorylation upon Interleukin-6 Stimulation: CONTRIBUTIONS OF Src- AND RECEPTOR-TYROSINE KINASES
J. Biol. Chem. 2005 280: 31478-31488. First Published on July 6, 2005; doi:10.1074/jbc.M506008200 [Abstract] [Full Text] [PDF]  

Eung-Ryoung Lee, Yong-Jin Kang, Jung-Hyun Kim, Hoon Taek Lee, and Ssang-Goo Cho
Modulation of Apoptosis in HaCaT Keratinocytes via Differential Regulation of ERK Signaling Pathway by Flavonoids
J. Biol. Chem. 2005 280: 31498-31507. First Published on July 13, 2005; doi:10.1074/jbc.M505537200 [Abstract] [Full Text] [PDF]  

Emma Jamieson, Mark M. W. Chong, Gregory R. Steinberg, Valentina Jovanovska, Barbara C. Fam, Denise V. R. Bullen, Ye Chen, Bruce E. Kemp, Joseph Proietto, Thomas W. H. Kay, and Sofianos Andrikopoulos
Socs1 Deficiency Enhances Hepatic Insulin Signaling
J. Biol. Chem. 2005 280: 31516-31521. First Published on June 27, 2005; doi:10.1074/jbc.M502163200 [Abstract] [Full Text] [PDF]  

Chuan He Yang, Aruna Murti, and Lawrence M. Pfeffer
Interferon Induces NF-{kappa}B-inducing Kinase/Tumor Necrosis Factor Receptor-associated Factor-dependent NF-{kappa}B Activation to Promote Cell Survival
J. Biol. Chem. 2005 280: 31530-31536. First Published on July 11, 2005; doi:10.1074/jbc.M503120200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

David E. Kang, Il Sang Yoon, Emanuela Repetto, Tracy Busse, Nader Yermian, Listya Ie, and Edward H. Koo
Presenilins Mediate Phosphatidylinositol 3-Kinase/AKT and ERK Activation via Select Signaling Receptors: SELECTIVITY OF PS2 IN PLATELET-DERIVED GROWTH FACTOR SIGNALING
J. Biol. Chem. 2005 280: 31537-31547. First Published on July 13, 2005; doi:10.1074/jbc.M500833200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Adrian P. Grech, Sandra Gardam, Tyani Chan, Rachel Quinn, Ruth Gonzales, Antony Basten, and Robert Brink
Tumor Necrosis Factor Receptor 2 (TNFR2) Signaling Is Negatively Regulated by a Novel, Carboxyl-terminal TNFR-associated Factor 2 (TRAF2)-binding Site
J. Biol. Chem. 2005 280: 31572-31581. First Published on July 14, 2005; doi:10.1074/jbc.M504849200 [Abstract] [Full Text] [PDF]  

Fred L. Robinson and Jack E. Dixon
The Phosphoinositide-3-phosphatase MTMR2 Associates with MTMR13, a Membrane-associated Pseudophosphatase Also Mutated in Type 4B Charcot-Marie-Tooth Disease
J. Biol. Chem. 2005 280: 31699-31707. First Published on July 5, 2005; doi:10.1074/jbc.M505159200 [Abstract] [Full Text] [PDF]  

Michelle E. Kimple, Andrew B. Nixon, Patrick Kelly, Candice L. Bailey, Kenneth H. Young, Timothy A. Fields, and Patrick J. Casey
A Role for Gz in Pancreatic Islet {beta}-Cell Biology
J. Biol. Chem. 2005 280: 31708-31713. First Published on July 6, 2005; doi:10.1074/jbc.M506700200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yuko Harada, Mihoko Sakai, Nobuhiro Kurabayashi, Tsuyoshi Hirota, and Yoshitaka Fukada
Ser-557-phosphorylated mCRY2 Is Degraded upon Synergistic Phosphorylation by Glycogen Synthase Kinase-3{beta}
J. Biol. Chem. 2005 280: 31714-31721. First Published on June 24, 2005; doi:10.1074/jbc.M506225200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Ajay Yadav, Anjana Kalita, Shivani Dhillon, and Kakoli Banerjee
JAK/STAT3 Pathway Is Involved in Survival of Neurons in Response to Insulin-like Growth Factor and Negatively Regulated by Suppressor of Cytokine Signaling-3
J. Biol. Chem. 2005 280: 31830-31840. First Published on July 5, 2005; doi:10.1074/jbc.M501316200 [Abstract] [Full Text] [PDF]  

Tomoaki Murakami, Hitoshi Takagi, Kiyoshi Suzuma, Izumi Suzuma, Hirokazu Ohashi, Daisuke Watanabe, Tomonari Ojima, Eri Suganami, Masafumi Kurimoto, Hideaki Kaneto, Yoshihito Honda, and Nagahisa Yoshimura
Angiopoietin-1 Attenuates H2O2-induced SEK1/JNK Phosphorylation through the Phosphatidylinositol 3-Kinase/Akt Pathway in Vascular Endothelial Cells
J. Biol. Chem. 2005 280: 31841-31849. First Published on July 6, 2005; doi:10.1074/jbc.M503108200 [Abstract] [Full Text] [PDF]  

Jon B. Klein, Michelle T. Barati, Rui Wu, David Gozal, Leroy R. Sachleben, Jr., Hina Kausar, John O. Trent, Evelyne Gozal, and Madhavi J. Rane
Akt-mediated Valosin-containing Protein 97 Phosphorylation Regulates Its Association with Ubiquitinated Proteins
J. Biol. Chem. 2005 280: 31870-31881. First Published on July 18, 2005; doi:10.1074/jbc.M501802200 [Abstract] [Full Text] [PDF]  

Ingrid Gsandtner, Christoforos Charalambous, Eduard Stefan, Egon Ogris, Michael Freissmuth, and Jürgen Zezula
Heterotrimeric G Protein-independent Signaling of a G Protein-coupled Receptor: DIRECT BINDING OF ARNO/CYTOHESIN-2 TO THE CARBOXYL TERMINUS OF THE A2A ADENOSINE RECEPTOR IS NECESSARY FOR SUSTAINED ACTIVATION OF THE ERK/MAP KINASE PATHWAY
J. Biol. Chem. 2005 280: 31898-31905. First Published on July 18, 2005; doi:10.1074/jbc.M506515200 [Abstract] [Full Text] [PDF]  

Kuntebommanahalli N. Thimmaiah, John B. Easton, Glen S. Germain, Christopher L. Morton, Shantaram Kamath, John K. Buolamwini, and Peter J. Houghton
Identification of N10-Substituted Phenoxazines as Potent and Specific Inhibitors of Akt Signaling
J. Biol. Chem. 2005 280: 31924-31935. First Published on July 11, 2005; doi:10.1074/jbc.M507057200 [Abstract] [Full Text] [PDF]  

Claire Jacob, Ping-Chang Yang, Dalila Darmoul, Silvia Amadesi, Toshiyuki Saito, Graeme S. Cottrell, Anne-Marie Coelho, Pamela Singh, Eileen F. Grady, Mary Perdue, and Nigel W. Bunnett
Mast Cell Tryptase Controls Paracellular Permeability of the Intestine: ROLE OF PROTEASE-ACTIVATED RECEPTOR 2 AND {beta}-ARRESTINS
J. Biol. Chem. 2005 280: 31936-31948. First Published on July 18, 2005; doi:10.1074/jbc.M506338200 [Abstract] [Full Text] [PDF]  

Cristinel Sandu, Evripidis Gavathiotis, Ted Huang, Iga Wegorzewska, and Milton H. Werner
A Mechanism for Death Receptor Discrimination by Death Adaptors
J. Biol. Chem. 2005 280: 31974-31980. First Published on July 8, 2005; doi:10.1074/jbc.M506938200 [Abstract] [Full Text] [PDF]  

Ju Young Kim and David Saffen
Activation of M1 Muscarinic Acetylcholine Receptors Stimulates the Formation of a Multiprotein Complex Centered on TRPC6 Channels
J. Biol. Chem. 2005 280: 32035-32047. First Published on June 30, 2005; doi:10.1074/jbc.M500429200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Junhong Han, Yu-ichi Tsukada, Eiji Hara, Naomi Kitamura, and Toshiaki Tanaka
Hepatocyte Growth Factor Induces Redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a Up-regulation, Leading to Cell Cycle Arrest at G1 in HepG2 Hepatoma Cells
J. Biol. Chem. 2005 280: 31548-31556. First Published on July 13, 2005; doi:10.1074/jbc.M503431200 [Abstract] [Full Text] [PDF]  

Atsushi Suzuki, Gen-ichi Kusakai, Yosuke Shimojo, Jian Chen, Tsutomu Ogura, Masanobu Kobayashi, and Hiroyasu Esumi
Involvement of Transforming Growth Factor-{beta}1 Signaling in Hypoxia-induced Tolerance to Glucose Starvation
J. Biol. Chem. 2005 280: 31557-31563. First Published on July 13, 2005; doi:10.1074/jbc.M503714200 [Abstract] [Full Text] [PDF]  

Shintaro Koga, Keiichiro Yogo, Kana Yoshikawa, Hidetomo Samori, Masashi Goto, Toshihiro Uchida, Norihiro Ishida, and Tatsuo Takeya
Physical and Functional Association of c-Src and Adhesion and Degranulation Promoting Adaptor Protein (ADAP) in Osteoclastogenesis in Vitro
J. Biol. Chem. 2005 280: 31564-31571. First Published on July 14, 2005; doi:10.1074/jbc.M502703200 [Abstract] [Full Text] [PDF]  

John R. L. Constable, Margaret E. Graham, Alan Morgan, and Robert D. Burgoyne
Amisyn Regulates Exocytosis and Fusion Pore Stability by Both Syntaxin-dependent and Syntaxin-independent Mechanisms
J. Biol. Chem. 2005 280: 31615-31623. First Published on July 20, 2005; doi:10.1074/jbc.M505858200 [Abstract] [Full Text] [PDF]  

Noora Kotaja, Betina Macho, and Paolo Sassone-Corsi
Microtubule-independent and Protein Kinase A-mediated Function of Kinesin KIF17b Controls the Intracellular Transport of Activator of CREM in Testis (ACT)
J. Biol. Chem. 2005 280: 31739-31745. First Published on July 7, 2005; doi:10.1074/jbc.M505971200 [Abstract] [Full Text] [PDF]  

Joanne Cleary, Kajal V. Sitwala, Michael S. Khodadoust, Roland P. S. Kwok, Nirit Mor-Vaknin, Marek Cebrat, Philip A. Cole, and David M. Markovitz
p300/CBP-associated Factor Drives DEK into Interchromatin Granule Clusters
J. Biol. Chem. 2005 280: 31760-31767. First Published on June 28, 2005; doi:10.1074/jbc.M500884200 [Abstract] [Full Text] [PDF]  

Praveen Kumar and Ching C. Wang
Depletion of Anaphase-promoting Complex or Cyclosome (APC/C) Subunit Homolog APC1 or CDC27 of Trypanosoma brucei Arrests the Procyclic Form in Metaphase but the Bloodstream Form in Anaphase
J. Biol. Chem. 2005 280: 31783-31791. First Published on July 1, 2005; doi:10.1074/jbc.M504326200 [Abstract] [Full Text] [PDF]  

Isabel Martinez-Pena y Valenzuela, Richard I. Hume, Eric Krejci, and Mohammed Akaaboune
In Vivo Regulation of Acetylcholinesterase Insertion at the Neuromuscular Junction
J. Biol. Chem. 2005 280: 31801-31808. First Published on July 5, 2005; doi:10.1074/jbc.M502874200 [Abstract] [Full Text] [PDF]  

Matthew D. Potter, Simone Barbero, and David A. Cheresh
Tyrosine Phosphorylation of VE-cadherin Prevents Binding of p120- and {beta}-Catenin and Maintains the Cellular Mesenchymal State
J. Biol. Chem. 2005 280: 31906-31912. First Published on July 18, 2005; doi:10.1074/jbc.M505568200 [Abstract] [Full Text] [PDF]  

Liang Cai, Nicholas Holoweckyj, Michael D. Schaller, and James E. Bear
Phosphorylation of Coronin 1B by Protein Kinase C Regulates Interaction with Arp2/3 and Cell Motility
J. Biol. Chem. 2005 280: 31913-31923. First Published on July 18, 2005; doi:10.1074/jbc.M504146200 [Abstract] [Full Text] [PDF]  

Luc Reininger, Oliver Billker, Rita Tewari, Arunima Mukhopadhyay, Clare Fennell, Dominique Dorin-Semblat, Caroline Doerig, Dean Goldring, Leonie Harmse, Lisa Ranford-Cartwright, Jeremy Packer, and Christian Doerig
A NIMA-related Protein Kinase Is Essential for Completion of the Sexual Cycle of Malaria Parasites
J. Biol. Chem. 2005 280: 31957-31964. First Published on June 21, 2005; doi:10.1074/jbc.M504523200 [Abstract] [Full Text] [PDF]  

Michael L. Paine, Wen Luo, Hong-Jun Wang, Pablo Bringas, Jr., Amanda Y. W. Ngan, Vetea G. Miklus, Dan-Hong Zhu, Mary MacDougall, Shane N. White, and Malcolm L. Snead
Dentin Sialoprotein and Dentin Phosphoprotein Overexpression during Amelogenesis
J. Biol. Chem. 2005 280: 31991-31998. First Published on July 13, 2005; doi:10.1074/jbc.M502991200 [Abstract] [Full Text] [PDF]  

In-Hyun Park and Jie Chen
Mammalian Target of Rapamycin (mTOR) Signaling Is Required for a Late-stage Fusion Process during Skeletal Myotube Maturation
J. Biol. Chem. 2005 280: 32009-32017. First Published on July 25, 2005; doi:10.1074/jbc.M506120200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Hong-Van Le, Andy J. Minn, and Joan Massagué
Cyclin-dependent Kinase Inhibitors Uncouple Cell Cycle Progression from Mitochondrial Apoptotic Functions in DNA-damaged Cancer Cells
J. Biol. Chem. 2005 280: 32018-32025. First Published on July 6, 2005; doi:10.1074/jbc.M504689200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Shinya Morimoto, Noriyuki Nishimura, Tomoya Terai, Shinji Manabe, Yasuyo Yamamoto, Wakako Shinahara, Hidenori Miyake, Seiki Tashiro, Mitsuo Shimada, and Takuya Sasaki
Rab13 mediates the continuous endocytic recycling of occludin to the cell surface. Vol. 280 (2005) 2220-2228
J. Biol. Chem. 2005 280: 32048. [Full Text] [PDF]  

Jeffrey Baldwin, Carolyn H. Michnoff, Nicholas A. Malmquist, John White, Michael G. Roth, Pradipsinh K. Rathod, and Margaret A. Phillips
High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. Vol. 280 (2005) 21847-21853
J. Biol. Chem. 2005 280: 32048-a. [Full Text] [PDF]  


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