JBC -- Table of Contents (Jan 28 2005, 280, (4))

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Christoph Benning and Hiroyuki Ohta: Three Enzyme Systems for Galactoglycerolipid Biosynthesis Are Coordinately Regulated in Plants
J. Biol. Chem. 2005 280: 2397-2400. First Published on December 6, 2004; doi:10.1074/jbc.R400032200 [Abstract] [Full Text] [PDF]

Accelerated Publications:

Pascal G. Wilmann, Jan Petersen, Rodney J. Devenish, Mark Prescott, and Jamie Rossjohn: Variations on the GFP Chromophore: A POLYPEPTIDE FRAGMENTATION WITHIN THE CHROMOPHORE REVEALED IN THE 2.1-Å CRYSTAL STRUCTURE OF A NONFLUORESCENT CHROMOPROTEIN FROM ANEMONIA SULCATA
J. Biol. Chem. 2005 280: 2401-2404. First Published on November 12, 2004; doi:10.1074/jbc.C400484200 [Abstract] [Full Text] [PDF]

Eleni Tzima, John S. Reader, Mohamad Irani-Tehrani, Karla L. Ewalt, Martin A. Schwartz, and Paul Schimmel: VE-cadherin Links tRNA Synthetase Cytokine to Anti-angiogenic Function
J. Biol. Chem. 2005 280: 2405-2408. First Published on December 3, 2004; doi:10.1074/jbc.C400431200 [Abstract] [Full Text] [PDF]

Françoise I. Bussière, Rupesh Chaturvedi, Yulan Cheng, Alain P. Gobert, Mohammad Asim, Darren R. Blumberg, Hangxiu Xu, Preston Y. Kim, Amy Hacker, Robert A. Casero, Jr., and Keith T. Wilson: Spermine Causes Loss of Innate Immune Response to Helicobacter pylori by Inhibition of Inducible Nitric-oxide Synthase Translation
J. Biol. Chem. 2005 280: 2409-2412. First Published on November 17, 2004; doi:10.1074/jbc.C400498200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Christian Lanciault and James J. Champoux: Effects of Unpaired Nucleotides within HIV-1 Genomic Secondary Structures on Pausing and Strand Transfer
J. Biol. Chem. 2005 280: 2413-2423. First Published on November 12, 2004; doi:10.1074/jbc.M410718200 [Abstract] [Full Text] [PDF]

Ningguang Luo and Laurie S. Kaguni: Mutations in the Spacer Region of Drosophila Mitochondrial DNA Polymerase Affect DNA Binding, Processivity, and the Balance between Pol and Exo Function
J. Biol. Chem. 2005 280: 2491-2497. First Published on November 10, 2004; doi:10.1074/jbc.M411447200 [Abstract] [Full Text] [PDF]

Isabelle S. Lucet, Fleur E. Tynan, Vicki Adams, Jamie Rossjohn, Dena Lyras, and Julian I. Rood: Identification of the Structural and Functional Domains of the Large Serine Recombinase TnpX from Clostridium perfringens
J. Biol. Chem. 2005 280: 2503-2511. First Published on November 12, 2004; doi:10.1074/jbc.M409702200 [Abstract] [Full Text] [PDF]

Ling Chen, Kelly M. Trujillo, Stephen Van Komen, Dong Hyun Roh, Lumir Krejci, L. Kevin Lewis, Michael A. Resnick, Patrick Sung, and Alan E. Tomkinson: Effect of Amino Acid Substitutions in the Rad50 ATP Binding Domain on DNA Double Strand Break Repair in Yeast
J. Biol. Chem. 2005 280: 2620-2627. First Published on November 16, 2004; doi:10.1074/jbc.M410192200 [Abstract] [Full Text] [PDF]

Marina Mapelli, Santosh Panjikar, and Paul A. Tucker: The Crystal Structure of the Herpes Simplex Virus 1 ssDNA-binding Protein Suggests the Structural Basis for Flexible, Cooperative Single-stranded DNA Binding
J. Biol. Chem. 2005 280: 2990-2997. First Published on October 26, 2004; doi:10.1074/jbc.M406780200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Mei Nie, Lisa Corbett, Alan J. Knox, and Linhua Pang: Differential Regulation of Chemokine Expression by Peroxisome Proliferator-activated Receptor ${gamma}$ Agonists: INTERACTIONS WITH GLUCOCORTICOIDS AND ${beta}$ ₂-AGONISTS
J. Biol. Chem. 2005 280: 2550-2561. First Published on November 5, 2004; doi:10.1074/jbc.M410616200 [Abstract] [Full Text] [PDF]

Justin Mostecki, Brian M. Showalter, and Paul B. Rothman: Early Growth Response-1 Regulates Lipopolysaccharide-induced Suppressor of Cytokine Signaling-1 Transcription
J. Biol. Chem. 2005 280: 2596-2605. First Published on November 15, 2004; doi:10.1074/jbc.M408938200 [Abstract] [Full Text] [PDF]

Marie-Ange Renault, Sandra Jalvy, Mylène Potier, Isabelle Belloc, Elisabeth Genot, Lodewijk V. Dekker, Claude Desgranges, and Alain-Pierre Gadeau: UTP Induces Osteopontin Expression through a Coordinate Action of NF ${kappa}$ B, Activator Protein-1, and Upstream Stimulatory Factor in Arterial Smooth Muscle Cells
J. Biol. Chem. 2005 280: 2708-2713. First Published on November 22, 2004; doi:10.1074/jbc.M411786200 [Abstract] [Full Text] [PDF]

Xiaoting Zhang, Ania Kolaczkowska, Frédéric Devaux, Sneh Lata Panwar, Timothy C. Hallstrom, Claude Jacq, and W. Scott Moye-Rowley: Transcriptional Regulation by Lge1p Requires a Function Independent of Its Role in Histone H2B Ubiquitination
J. Biol. Chem. 2005 280: 2759-2770. First Published on November 4, 2004; doi:10.1074/jbc.M408333200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Emmanuel Agbottah, Cynthia de La Fuente, Sergie Nekhai, Anna Barnett, Athos Gianella-Borradori, Anne Pumfery, and Fatah Kashanchi: Antiviral Activity of CYC202 in HIV-1-infected Cells
J. Biol. Chem. 2005 280: 3029-3042. First Published on November 5, 2004; doi:10.1074/jbc.M406435200 [Abstract] [Full Text] [PDF]

Rongtuan Lin, Long Yang, Meztli Arguello, Claudia Penafuerte, and John Hiscott: A CRM1-dependent Nuclear Export Pathway Is Involved in the Regulation of IRF-5 Subcellular Localization
J. Biol. Chem. 2005 280: 3088-3095. First Published on November 19, 2004; doi:10.1074/jbc.M408452200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Eva Vondrusková, Janny van den Burg, Alena Zíková, Nancy Lewis Ernst, Kenneth Stuart, Rob Benne, and Julius Lukes: RNA Interference Analyses Suggest a Transcript-specific Regulatory Role for Mitochondrial RNA-binding Proteins MRP1 and MRP2 in RNA Editing and Other RNA Processing in Trypanosoma brucei
J. Biol. Chem. 2005 280: 2429-2438. First Published on October 25, 2004; doi:10.1074/jbc.M405933200 [Abstract] [Full Text] [PDF]

Charles E. Bullerwell and Michael W. Gray: In Vitro Characterization of a tRNA Editing Activity in the Mitochondria of Spizellomyces punctatus, a Chytridiomycete Fungus
J. Biol. Chem. 2005 280: 2463-2470. First Published on November 15, 2004; doi:10.1074/jbc.M411273200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Silvia Olivari, Carmela Galli, Heli Alanen, Lloyd Ruddock, and Maurizio Molinari: A Novel Stress-induced EDEM Variant Regulating Endoplasmic Reticulum-associated Glycoprotein Degradation
J. Biol. Chem. 2005 280: 2424-2428. First Published on December 3, 2004; doi:10.1074/jbc.C400534200 [Abstract] [Full Text] [PDF]

Valérie Heurgué-Hamard, Stéphanie Champ, Liliana Mora, Tatiana Merkoulova-Rainon, Lev L. Kisselev, and Richard H. Buckingham: The Glutamine Residue of the Conserved GGQ Motif in Saccharomyces cerevisiae Release Factor eRF1 Is Methylated by the Product of the YDR140w Gene
J. Biol. Chem. 2005 280: 2439-2445. First Published on October 27, 2004; doi:10.1074/jbc.M407252200 [Abstract] [Full Text] [PDF]

Steffen Augustin, Mark Nolden, Stefan Müller, Olaf Hardt, Isabel Arnold, and Thomas Langer: Characterization of Peptides Released from Mitochondria: EVIDENCE FOR CONSTANT PROTEOLYSIS AND PEPTIDE EFFLUX
J. Biol. Chem. 2005 280: 2691-2699. First Published on November 19, 2004; doi:10.1074/jbc.M410609200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lionel A. Tintignac, Julie Lagirand, Sabrina Batonnet, Valentina Sirri, Marie Pierre Leibovitch, and Serge A. Leibovitch: Degradation of MyoD Mediated by the SCF (MAFbx) Ubiquitin Ligase
J. Biol. Chem. 2005 280: 2847-2856. First Published on November 5, 2004; doi:10.1074/jbc.M411346200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pavan K. Auluck, Marc C. Meulener, and Nancy M. Bonini: Mechanisms of Suppression of ${alpha}$ -Synuclein Neurotoxicity by Geldanamycin in Drosophila
J. Biol. Chem. 2005 280: 2873-2878. First Published on November 18, 2004; doi:10.1074/jbc.M412106200 [Abstract] [Full Text] [PDF] [Supplemental Data]

William S. Bowen, Natalya Van Dyke, Emanuel J. Murgola, J. Stephen Lodmell, and Walter E. Hill: Interaction of Thiostrepton and Elongation Factor-G with the Ribosomal Protein L11-binding Domain
J. Biol. Chem. 2005 280: 2934-2943. First Published on October 18, 2004; doi:10.1074/jbc.M407008200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Elisabeth O. Hochleitner, Berthold Kastner, Thomas Fröhlich, Alexander Schmidt, Reinhard Lührmann, Georg Arnold, and Friedrich Lottspeich: Protein Stoichiometry of a Multiprotein Complex, the Human Spliceosomal U1 Small Nuclear Ribonucleoprotein: ABSOLUTE QUANTIFICATION USING ISOTOPE-CODED TAGS AND MASS SPECTROMETRY
J. Biol. Chem. 2005 280: 2536-2542. First Published on November 3, 2004; doi:10.1074/jbc.M409587200 [Abstract] [Full Text] [PDF]

Marta C. Justino, João B. Vicente, Miguel Teixeira, and Lígia M. Saraiva: New Genes Implicated in the Protection of Anaerobically Grown Escherichia coli against Nitric Oxide
J. Biol. Chem. 2005 280: 2636-2643. First Published on November 16, 2004; doi:10.1074/jbc.M411070200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Stephanie Cratic-McDaniel, Jan H. Hoh, and Terrone L. Rosenberry: Amyloid- ${beta}$ Protofibrils Differ from Amyloid- ${beta}$ Aggregates Induced in Dilute Hexafluoroisopropanol in Stability and Morphology
J. Biol. Chem. 2005 280: 2471-2480. First Published on November 4, 2004; doi:10.1074/jbc.M410553200 [Abstract] [Full Text] [PDF]

Katerina Papanikolopoulou, Guy Schoehn, Vincent Forge, V. Trevor Forsyth, Christian Riekel, Jean-François Hernandez, Rob W. H. Ruigrok, and Anna Mitraki: Amyloid Fibril Formation from Sequences of a Natural ${beta}$ -Structured Fibrous Protein, the Adenovirus Fiber
J. Biol. Chem. 2005 280: 2481-2490. First Published on October 27, 2004; doi:10.1074/jbc.M406282200 [Abstract] [Full Text] [PDF]

Claire L. Harris, Rachel J. M. Abbott, Richard A. Smith, B. Paul Morgan, and Susan M. Lea: Molecular Dissection of Interactions between Components of the Alternative Pathway of Complement and Decay Accelerating Factor (CD55)
J. Biol. Chem. 2005 280: 2569-2578. First Published on November 9, 2004; doi:10.1074/jbc.M410179200 [Abstract] [Full Text] [PDF]

Yuji Shitaka, Chieko Kimura, and Masao Miki: The Rates of Switching Movement of Troponin T between Three States of Skeletal Muscle Thin Filaments Determined by Fluorescence Resonance Energy Transfer
J. Biol. Chem. 2005 280: 2613-2619. First Published on November 16, 2004; doi:10.1074/jbc.M408553200 [Abstract] [Full Text] [PDF]

Antonio Mario Tamburro, Antonietta Pepe, Brigida Bochicchio, Daniela Quaglino, and Ivonne Pasquali Ronchetti: Supramolecular Amyloid-like Assembly of the Polypeptide Sequence Coded by Exon 30 of Human Tropoelastin
J. Biol. Chem. 2005 280: 2682-2690. First Published on November 18, 2004; doi:10.1074/jbc.M411617200 [Abstract] [Full Text] [PDF]

Ruiying Wu, Eric Patrick Skaar, Rongguang Zhang, Grazyna Joachimiak, Piotr Gornicki, Olaf Schneewind, and Andrzej Joachimiak: Staphylococcus aureus IsdG and IsdI, Heme-degrading Enzymes with Structural Similarity to Monooxygenases
J. Biol. Chem. 2005 280: 2840-2846. First Published on October 31, 2004; doi:10.1074/jbc.M409526200 [Abstract] [Full Text] [PDF]

Thomas T. Egelhoff, Daniel Croft, and Paul A. Steimle: Actin Activation of Myosin Heavy Chain Kinase A in Dictyostelium: A BIOCHEMICAL MECHANISM FOR THE SPATIAL REGULATION OF MYOSIN II FILAMENT DISASSEMBLY
J. Biol. Chem. 2005 280: 2879-2887. First Published on November 14, 2004; doi:10.1074/jbc.M410803200 [Abstract] [Full Text] [PDF]

Maria Teresa Fiorillo, Christine Rückert, Martin Hülsmeyer, Rosa Sorrentino, Wolfram Saenger, Andreas Ziegler, and Barbara Uchanska-Ziegler: Allele-dependent Similarity between Viral and Self-peptide Presentation by HLA-B27 Subtypes
J. Biol. Chem. 2005 280: 2962-2971. First Published on November 10, 2004; doi:10.1074/jbc.M410807200 [Abstract] [Full Text] [PDF]

Martin Hülsmeyer, Patrick Chames, Roman C. Hillig, Robyn L. Stanfield, Gerhard Held, Pierre G. Coulie, Claudia Alings, Gabriele Wille, Wolfram Saenger, Barbara Uchanska-Ziegler, Hennie R. Hoogenboom, and Andreas Ziegler: A Major Histocompatibility Complex·Peptide-restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: CRYSTAL STRUCTURE OF HUMAN LEUKOCYTE ANTIGEN (HLA)-A1·MAGE-A1 IN COMPLEX WITH FAB-HYB3
J. Biol. Chem. 2005 280: 2972-2980. First Published on November 10, 2004; doi:10.1074/jbc.M411323200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Kenneth V. Mills, Deirdre M. Dorval, and Katherine T. Lewandowski: Kinetic Analysis of the Individual Steps of Protein Splicing for the Pyrococcus abyssi PolII Intein
J. Biol. Chem. 2005 280: 2714-2720. First Published on November 22, 2004; doi:10.1074/jbc.M412313200 [Abstract] [Full Text] [PDF]

Wendy J. Carter, Evis Cama, and James A. Huntington: Crystal Structure of Thrombin Bound to Heparin
J. Biol. Chem. 2005 280: 2745-2749. First Published on November 17, 2004; doi:10.1074/jbc.M411606200 [Abstract] [Full Text] [PDF]

Kenneth M. Humphries, Michael S. Deal, and Susan S. Taylor: Enhanced Dephosphorylation of cAMP-dependent Protein Kinase by Oxidation and Thiol Modification
J. Biol. Chem. 2005 280: 2750-2758. First Published on November 8, 2004; doi:10.1074/jbc.M410242200 [Abstract] [Full Text] [PDF]

Jinling Wang, Latesh Lad, Thomas L. Poulos, and Paul R. Ortiz de Montellano: Regiospecificity Determinants of Human Heme Oxygenase: DIFFERENTIAL NADPH- AND ASCORBATE-DEPENDENT HEME CLEAVAGE BY THE R183E MUTANT
J. Biol. Chem. 2005 280: 2797-2806. First Published on November 3, 2004; doi:10.1074/jbc.M411229200 [Abstract] [Full Text] [PDF]

Ana Mirela Neculai, Dante Neculai, Christian Griesinger, Julia A. Vorholt, and Stefan Becker: A Dynamic Zinc Redox Switch
J. Biol. Chem. 2005 280: 2826-2830. First Published on November 17, 2004; doi:10.1074/jbc.C400517200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Keith J. Chappell, Tessa A. Nall, Martin J. Stoermer, Ning-Xia Fang, Joel D. A. Tyndall, David P. Fairlie, and Paul R. Young: Site-directed Mutagenesis and Kinetic Studies of the West Nile Virus NS3 Protease Identify Key Enzyme-Substrate Interactions
J. Biol. Chem. 2005 280: 2896-2903. First Published on October 19, 2004; doi:10.1074/jbc.M409931200 [Abstract] [Full Text] [PDF]

Toshitaka Matsui, Momoko Furukawa, Masaki Unno, Takeshi Tomita, and Masao Ikeda-Saito: Roles of Distal Asp in Heme Oxygenase from Corynebacterium diphtheriae, HmuO: A WATER-DRIVEN OXYGEN ACTIVATION MECHANISM
J. Biol. Chem. 2005 280: 2981-2989. First Published on November 4, 2004; doi:10.1074/jbc.M410263200 [Abstract] [Full Text] [PDF]

Eva Johansson, Mathias Fanø, Julie H. Bynck, Jan Neuhard, Sine Larsen, Bent W. Sigurskjold, Ulla Christensen, and Martin Willemoës: Structures of dCTP Deaminase from Escherichia coli with Bound Substrate and Product: REACTION MECHANISM AND DETERMINANTS OF MONO- AND BIFUNCTIONALITY FOR A FAMILY OF ENZYMES
J. Biol. Chem. 2005 280: 3051-3059. First Published on November 10, 2004; doi:10.1074/jbc.M409534200 [Abstract] [Full Text] [PDF]

Magnus S. Alphey, Wenhua Yu, Emma Byres, Ding Li, and William N. Hunter: Structure and Reactivity of Human Mitochondrial 2,4-Dienoyl-CoA Reductase: ENZYME-LIGAND INTERACTIONS IN A DISTINCTIVE SHORT-CHAIN REDUCTASE ACTIVE SITE
J. Biol. Chem. 2005 280: 3068-3077. First Published on November 6, 2004; doi:10.1074/jbc.M411069200 [Abstract] [Full Text] [PDF]

Dantong Wang, Xavier De Deken, Milutin Milenkovic, Yue Song, Isabelle Pirson, Jacques E. Dumont, and Françoise Miot: Identification of a Novel Partner of Duox: EFP1, A THIOREDOXIN-RELATED PROTEIN
J. Biol. Chem. 2005 280: 3096-3103. First Published on November 22, 2004; doi:10.1074/jbc.M407709200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Hitoshi Saito, Akira Maeda, Shu-ichi Ohtomo, Michinori Hirata, Kenichiro Kusano, Shigeaki Kato, Etsuro Ogata, Hiroko Segawa, Ken-ichi Miyamoto, and Naoshi Fukushima: Circulating FGF-23 Is Regulated by 1 ${alpha}$ ,25-Dihydroxyvitamin D₃ and Phosphorus in Vivo
J. Biol. Chem. 2005 280: 2543-2549. First Published on November 5, 2004; doi:10.1074/jbc.M408903200 [Abstract] [Full Text] [PDF]

Natalia Battchikova, Pengpeng Zhang, Stephen Rudd, Teruo Ogawa, and Eva-Mari Aro: Identification of NdhL and Ssl1690 (NdhO) in NDH-1L and NDH-1M Complexes of Synechocystis sp. PCC 6803
J. Biol. Chem. 2005 280: 2587-2595. First Published on November 17, 2004; doi:10.1074/jbc.M410914200 [Abstract] [Full Text] [PDF]

Peter Gin and Catherine F. Clarke: Genetic Evidence for a Multi-subunit Complex in Coenzyme Q Biosynthesis in Yeast and the Role of the Coq1 Hexaprenyl Diphosphate Synthase
J. Biol. Chem. 2005 280: 2676-2681. First Published on November 17, 2004; doi:10.1074/jbc.M411527200 [Abstract] [Full Text] [PDF]

James E. Turner, Karen Greville, Elaine C. Murphy, and Mark A. Hooks: Characterization of Arabidopsis Fluoroacetate-resistant Mutants Reveals the Principal Mechanism of Acetate Activation for Entry into the Glyoxylate Cycle
J. Biol. Chem. 2005 280: 2780-2787. First Published on November 8, 2004; doi:10.1074/jbc.M407291200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Steffen K. Meurer, Lidia Tihaa, Birgit Lahme, Axel M. Gressner, and Ralf Weiskirchen: Identification of Endoglin in Rat Hepatic Stellate Cells: NEW INSIGHTS INTO TRANSFORMING GROWTH FACTOR ${beta}$ RECEPTOR SIGNALING
J. Biol. Chem. 2005 280: 3078-3087. First Published on November 10, 2004; doi:10.1074/jbc.M405411200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lipids and Lipoproteins:

Kevin P. Becker, Kazuyuki Kitatani, Jolanta Idkowiak-Baldys, Jacek Bielawski, and Yusuf A. Hannun: Selective Inhibition of Juxtanuclear Translocation of Protein Kinase C ${beta}$ II by a Negative Feedback Mechanism Involving Ceramide Formed from the Salvage Pathway
J. Biol. Chem. 2005 280: 2606-2612. First Published on November 16, 2004; doi:10.1074/jbc.M409066200 [Abstract] [Full Text] [PDF]

Vanna Chigorno, Claudia Giannotta, Elena Ottico, Mariateresa Sciannamblo, Joanna Mikulak, Alessandro Prinetti, and Sandro Sonnino: Sphingolipid Uptake by Cultured Cells: COMPLEX AGGREGATES OF CELL SPHINGOLIPIDS WITH SERUM PROTEINS AND LIPOPROTEINS ARE RAPIDLY CATABOLIZED
J. Biol. Chem. 2005 280: 2668-2675. First Published on November 17, 2004; doi:10.1074/jbc.M407749200 [Abstract] [Full Text] [PDF]

Lei Cai, Maria C. de Beer, Frederick C. de Beer, and Deneys R. van der Westhuyzen: Serum Amyloid A Is a Ligand for Scavenger Receptor Class B Type I and Inhibits High Density Lipoprotein Binding and Selective Lipid Uptake
J. Biol. Chem. 2005 280: 2954-2961. First Published on November 23, 2004; doi:10.1074/jbc.M411555200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Helmut Hofemeister and Peter O'Hare: Analysis of the Localization and Topology of Nurim, a Polytopic Protein Tightly Associated with the Inner Nuclear Membrane
J. Biol. Chem. 2005 280: 2512-2521. First Published on November 12, 2004; doi:10.1074/jbc.M410504200 [Abstract] [Full Text] [PDF]

Tip W. Loo, M. Claire Bartlett, and David M. Clarke: The Dileucine Motif at the COOH Terminus of Human Multidrug Resistance P-glycoprotein Is Important for Folding but Not Activity
J. Biol. Chem. 2005 280: 2522-2528. First Published on November 12, 2004; doi:10.1074/jbc.M411483200 [Abstract] [Full Text] [PDF]

Julia Adler and Eitan Bibi: Promiscuity in the Geometry of Electrostatic Interactions between the Escherichia coli Multidrug Resistance Transporter MdfA and Cationic Substrates
J. Biol. Chem. 2005 280: 2721-2729. First Published on November 22, 2004; doi:10.1074/jbc.M412332200 [Abstract] [Full Text] [PDF]

Mark F. Rosenberg, Richard Callaghan, Szabolcs Modok, Christopher F. Higgins, and Robert C. Ford: Three-dimensional Structure of P-glycoprotein: THE TRANSMEMBRANE REGIONS ADOPT AN ASYMMETRIC CONFIGURATION IN THE NUCLEOTIDE-BOUND STATE
J. Biol. Chem. 2005 280: 2857-2862. First Published on October 13, 2004; doi:10.1074/jbc.M410296200 [Abstract] [Full Text] [PDF]

Takeshi Nagai, Akio Abe, and Chihiro Sasakawa: Targeting of Enteropathogenic Escherichia coli EspF to Host Mitochondria Is Essential for Bacterial Pathogenesis: CRITICAL ROLE OF THE 16TH LEUCINE RESIDUE IN EspF
J. Biol. Chem. 2005 280: 2998-3011. First Published on November 8, 2004; doi:10.1074/jbc.M411550200 [Abstract] [Full Text] [PDF]

Jiri Ködding, Frank Killig, Patrick Polzer, S. Peter Howard, Kay Diederichs, and Wolfram Welte: Crystal Structure of a 92-Residue C-terminal Fragment of TonB from Escherichia coli Reveals Significant Conformational Changes Compared to Structures of Smaller TonB Fragments
J. Biol. Chem. 2005 280: 3022-3028. First Published on November 2, 2004; doi:10.1074/jbc.M411155200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Zhiwei He, Yong-Yeon Cho, Wei-Ya Ma, Hong Seok Choi, Ann M. Bode, and Zigang Dong: Regulation of Ultraviolet B-induced Phosphorylation of Histone H3 at Serine 10 by Fyn Kinase
J. Biol. Chem. 2005 280: 2446-2454. First Published on November 10, 2004; doi:10.1074/jbc.M402053200 [Abstract] [Full Text] [PDF]

Randal R. Nixon: Prion-associated Increases in Src-family Kinases
J. Biol. Chem. 2005 280: 2455-2462. First Published on November 15, 2004; doi:10.1074/jbc.M410883200 [Abstract] [Full Text] [PDF]

Jong-In Park, Emma J. Collinson, Chris M. Grant, and Ian W. Dawes: Rom2p, the Rho1 GTP/GDP Exchange Factor of Saccharomyces cerevisiae, Can Mediate Stress Responses via the Ras-cAMP Pathway
J. Biol. Chem. 2005 280: 2529-2535. First Published on November 15, 2004; doi:10.1074/jbc.M407900200 [Abstract] [Full Text] [PDF]

Xianlong Gao, Ziyun Du, and Tarun B. Patel: Copper and Zinc Inhibit G ${alpha}$ _s Function: A NUCLEOTIDE-FREE STATE OF G ${alpha}$ _s INDUCED BY Cu²⁺ AND Zn²⁺
J. Biol. Chem. 2005 280: 2579-2586. First Published on November 15, 2004; doi:10.1074/jbc.M409791200 [Abstract] [Full Text] [PDF]

Hendrik Ungefroren, Stephanie Groth, Maren Ruhnke, Holger Kalthoff, and Fred Fändrich: Transforming Growth Factor- ${beta}$ (TGF- ${beta}$ ) Type I Receptor/ALK5-dependent Activation of the GADD45 ${beta}$ Gene Mediates the Induction of Biglycan Expression by TGF- ${beta}$
J. Biol. Chem. 2005 280: 2644-2652. First Published on November 16, 2004; doi:10.1074/jbc.M411925200 [Abstract] [Full Text] [PDF]

Mitsutoshi Tsukimoto, Hitoshi Harada, Akira Ikari, and Kuniaki Takagi: Involvement of Chloride in Apoptotic Cell Death Induced by Activation of ATP-sensitive P2X₇ Purinoceptor
J. Biol. Chem. 2005 280: 2653-2658. First Published on November 17, 2004; doi:10.1074/jbc.M411072200 [Abstract] [Full Text] [PDF]

Marcus Buschbeck and Axel Ullrich: The Unique C-terminal Tail of the Mitogen-activated Protein Kinase ERK5 Regulates Its Activation and Nuclear Shuttling
J. Biol. Chem. 2005 280: 2659-2667. First Published on November 17, 2004; doi:10.1074/jbc.M412599200 [Abstract] [Full Text] [PDF]

Xin Chen, Jia-Chun Dai, Stephanie A. Orellana, and Edward M. Greenfield: Endogenous Protein Kinase Inhibitor ${gamma}$ Terminates Immediate-early Gene Expression Induced by cAMP-dependent Protein Kinase (PKA) Signaling: TERMINATION DEPENDS ON PKA INACTIVATION RATHER THAN PKA EXPORT FROM THE NUCLEUS
J. Biol. Chem. 2005 280: 2700-2707. First Published on November 19, 2004; doi:10.1074/jbc.M412558200 [Abstract] [Full Text] [PDF]

Antony M. Jose and Michael R. Koelle: Domains, Amino Acid Residues, and New Isoforms of Caenorhabditis elegans Diacylglycerol Kinase 1 (DGK-1) Important for Terminating Diacylglycerol Signaling in Vivo
J. Biol. Chem. 2005 280: 2730-2736. First Published on November 24, 2004; doi:10.1074/jbc.M409460200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Esther Latres, Ami R. Amini, Ashley A. Amini, Jennifer Griffiths, Francis J. Martin, Yi Wei, Hsin Chieh Lin, George D. Yancopoulos, and David J. Glass: Insulin-like Growth Factor-1 (IGF-1) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Pathway
J. Biol. Chem. 2005 280: 2737-2744. First Published on November 17, 2004; doi:10.1074/jbc.M407517200 [Abstract] [Full Text] [PDF]

Yao-Ting Huang, Dong-Ming Huang, Jih-Hwa Guh, I-Li Chen, Cherng-Chyi Tzeng, and Che-Ming Teng: CIL-102 Interacts with Microtubule Polymerization and Causes Mitotic Arrest following Apoptosis in the Human Prostate Cancer PC-3 Cell Line
J. Biol. Chem. 2005 280: 2771-2779. First Published on November 9, 2004; doi:10.1074/jbc.M408850200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Elena V. Kostenko, Gwendolyn M. Mahon, Li Cheng, and Ian P. Whitehead: The Sec14 Homology Domain Regulates the Cellular Distribution and Transforming Activity of the Rho-specific Guanine Nucleotide Exchange Factor Dbs
J. Biol. Chem. 2005 280: 2807-2817. First Published on November 5, 2004; doi:10.1074/jbc.M411139200 [Abstract] [Full Text] [PDF]

Qin Li, Tomo-o Ishikawa, Hiroyuki Miyoshi, Masanobu Oshima, and Makoto M. Taketo: A Targeted Mutation of Nkd1 Impairs Mouse Spermatogenesis
J. Biol. Chem. 2005 280: 2831-2839. First Published on November 16, 2004; doi:10.1074/jbc.M405680200 [Abstract] [Full Text] [PDF]

So-Young Rah, Kwang-Hyun Park, Myung-Kwan Han, Mie-Jae Im, and Uh-Hyun Kim: Activation of CD38 by Interleukin-8 Signaling Regulates Intracellular Ca²⁺ Level and Motility of Lymphokine-activated Killer Cells
J. Biol. Chem. 2005 280: 2888-2895. First Published on November 19, 2004; doi:10.1074/jbc.M409592200 [Abstract] [Full Text] [PDF]

Andreas Panopoulos, Maged Harraz, John F. Engelhardt, and Ebrahim Zandi: Iron-mediated H₂O₂ Production as a Mechanism for Cell Type-specific Inhibition of Tumor Necrosis Factor ${alpha}$ -Induced but Not Interleukin-1 ${beta}$ -induced I ${kappa}$ B Kinase Complex/Nuclear Factor- ${kappa}$ B Activation
J. Biol. Chem. 2005 280: 2912-2923. First Published on November 17, 2004; doi:10.1074/jbc.M409524200 [Abstract] [Full Text] [PDF]

Dazhong Xu, Anthony Makkinje, and John M. Kyriakis: Gene 33 Is an Endogenous Inhibitor of Epidermal Growth Factor (EGF) Receptor Signaling and Mediates Dexamethasone-induced Suppression of EGF Function
J. Biol. Chem. 2005 280: 2924-2933. First Published on November 19, 2004; doi:10.1074/jbc.M408907200 [Abstract] [Full Text] [PDF]

Jian-Hong Pang, Astrid Kraemer, Samantha J. Stehbens, Margaret C. Frame, and Alpha S. Yap: Recruitment of Phosphoinositide 3-Kinase Defines a Positive Contribution of Tyrosine Kinase Signaling to E-cadherin Function
J. Biol. Chem. 2005 280: 3043-3050. First Published on November 19, 2004; doi:10.1074/jbc.M412148200 [Abstract] [Full Text] [PDF]

Stefan Kippenberger, Stefan Loitsch, Maike Guschel, Jutta Müller, Yvonne Knies, Roland Kaufmann, and August Bernd: Mechanical Stretch Stimulates Protein Kinase B/Akt Phosphorylation in Epidermal Cells via Angiotensin II Type 1 Receptor and Epidermal Growth Factor Receptor
J. Biol. Chem. 2005 280: 3060-3067. First Published on November 15, 2004; doi:10.1074/jbc.M409590200 [Abstract] [Full Text] [PDF]

Ling Qin, Xin Li, Jae-Kyun Ko, and Nicola C. Partridge: Parathyroid Hormone Uses Multiple Mechanisms to Arrest the Cell Cycle Progression of Osteoblastic Cells from G₁ to S Phase
J. Biol. Chem. 2005 280: 3104-3111. First Published on October 28, 2004; doi:10.1074/jbc.M409846200 [Abstract] [Full Text] [PDF]

Nagadhara Dronadula, Zhimin Liu, Chunmei Wang, Huiqing Cao, and Gadiparthi N. Rao: STAT-3-dependent Cytosolic Phospholipase A₂ Expression Is Required for Thrombin-induced Vascular Smooth Muscle Cell Motility
J. Biol. Chem. 2005 280: 3112-3120. First Published on November 16, 2004; doi:10.1074/jbc.M409739200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

David G. Winkler, May S. Kung Sutherland, Ethan Ojala, Eileen Turcott, James C. Geoghegan, Diana Shpektor, John E. Skonier, Changpu Yu, and John A. Latham: Sclerostin Inhibition of Wnt-3a-induced C3H10T1/2 Cell Differentiation Is Indirect and Mediated by Bone Morphogenetic Proteins
J. Biol. Chem. 2005 280: 2498-2502. First Published on November 12, 2004; doi:10.1074/jbc.M400524200 [Abstract] [Full Text] [PDF]

Claudia Mitchell, Mary Nivison, Leslie F. Jackson, Richard Fox, David C. Lee, Jean S. Campbell, and Nelson Fausto: Heparin-binding Epidermal Growth Factor-like Growth Factor Links Hepatocyte Priming with Cell Cycle Progression during Liver Regeneration
J. Biol. Chem. 2005 280: 2562-2568. First Published on November 8, 2004; doi:10.1074/jbc.M412372200 [Abstract] [Full Text] [PDF]

Osigwe Esue, Maria Cordero, Denis Wirtz, and Yiider Tseng: The Assembly of MreB, a Prokaryotic Homolog of Actin
J. Biol. Chem. 2005 280: 2628-2635. First Published on November 16, 2004; doi:10.1074/jbc.M410298200 [Abstract] [Full Text] [PDF]

Chuan-ju Liu, Eric Chang, Jin Yu, Cathy S. Carlson, Lisa Prazak, Xiu-Ping Yu, Bo Ding, Peter Lengyel, and Paul E. Di Cesare: The Interferon-inducible p204 Protein Acts as a Transcriptional Coactivator of Cbfa1 and Enhances Osteoblast Differentiation
J. Biol. Chem. 2005 280: 2788-2796. First Published on November 19, 2004; doi:10.1074/jbc.M412604200 [Abstract] [Full Text] [PDF]

Alessandra B. Benedito, Maria Lehtinen, Ramiro Massol, Ulisses Gazos Lopes, Tomas Kirchhausen, Anjana Rao, and Azad Bonni: The Transcription Factor NFAT3 Mediates Neuronal Survival
J. Biol. Chem. 2005 280: 2818-2825. First Published on November 10, 2004; doi:10.1074/jbc.M408741200 [Abstract] [Full Text] [PDF]

An Wu, Xiao Tu, Marco Prisco, and Renato Baserga: Regulation of Upstream Binding Factor 1 Activity by Insulin-like Growth Factor I Receptor Signaling
J. Biol. Chem. 2005 280: 2863-2872. First Published on November 8, 2004; doi:10.1074/jbc.M406138200 [Abstract] [Full Text] [PDF]

Oleg M. Alekseev, Esther E. Widgren, Richard T. Richardson, and Michael G. O'Rand: Association of NASP with HSP90 in Mouse Spermatogenic Cells: STIMULATION OF ATPase ACTIVITY AND TRANSPORT OF LINKER HISTONES INTO NUCLEI
J. Biol. Chem. 2005 280: 2904-2911. First Published on November 8, 2004; doi:10.1074/jbc.M410397200 [Abstract] [Full Text] [PDF]

Hiroko Kojima and Toshimasa Uemura: Strong and Rapid Induction of Osteoblast Differentiation by Cbfa1/Til-1 Overexpression for Bone Regeneration
J. Biol. Chem. 2005 280: 2944-2953. First Published on November 10, 2004; doi:10.1074/jbc.M311598200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chang Feng Chen and David Lohnes: Dominant-negative Retinoic Acid Receptors Elicit Epidermal Defects through a Non-canonical Pathway
J. Biol. Chem. 2005 280: 3012-3021. First Published on November 4, 2004; doi:10.1074/jbc.M411522200 [Abstract] [Full Text] [PDF]