JBC -- Table of Contents (Nov 25 2005, 280, (47))

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Reflections:

Uriel Z. Littauer: From Polynucleotide Phosphorylase to Neurobiology
J. Biol. Chem. 2005 280: 38889-38897. First Published ; doi:10.1074/JBC.X500007200 [Full Text] [PDF]

Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Pioneering the Field of Oxygenases through the Study of Tryptophan Metabolism: the Work of Osamu Hayaishi
STUDIES ON OXYGENASES. ENZYMATIC FORMATION OF KYNURENINE FROM TRYPTOPHAN (Osamu Hayaishi, Simon Rothberg, Alan H. Mehler, and Yoshitaka Saito J. Biol. Chem. 229, 889-896)
STUDIES ON OXYGENASES. PYROCATECHASE (Osamu Hayaishi, Masayuki Katagiri, and Simon Rothberg J. Biol. Chem. 229, 905-920)
J. Biol. Chem. 2005 280: e44. [Full Text]

Accelerated Publications:

David J. Bettoun, Angela Scafonas, Su Jane Rutledge, Paul Hodor, Oliver Chen, Carlo Gambone, Robert Vogel, Sheila McElwee-Witmer, Chang Bai, Leonard Freedman, and Azriel Schmidt: Interaction between the Androgen Receptor and RNase L Mediates a Cross-talk between the Interferon and Androgen Signaling Pathways
J. Biol. Chem. 2005 280: 38898-38901. First Published on September 14, 2005; doi:10.1074/jbc.C500324200 [Abstract] [Full Text] [PDF] [Supplemental Data]

DNA: Replication, Repair, and Recombination:

Jung-Suk Sung, Michael S. DeMott, and Bruce Demple: Long-patch Base Excision DNA Repair of 2-Deoxyribonolactone Prevents the Formation of DNA-Protein Cross-links with DNA Polymerase ${beta}$
J. Biol. Chem. 2005 280: 39095-39103. First Published on September 27, 2005; doi:10.1074/jbc.M506480200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gregor Krings and Deepak Bastia: Sap1p Binds to Ter1 at the Ribosomal DNA of Schizosaccharomyces pombe and Causes Polar Replication Fork Arrest
J. Biol. Chem. 2005 280: 39135-39142. First Published on September 28, 2005; doi:10.1074/jbc.M508996200 [Abstract] [Full Text] [PDF]

A. Kathleen McClendon, A. Chapin Rodriguez, and Neil Osheroff: Human Topoisomerase II ${alpha}$ Rapidly Relaxes Positively Supercoiled DNA: IMPLICATIONS FOR ENZYME ACTION AHEAD OF REPLICATION FORKS
J. Biol. Chem. 2005 280: 39337-39345. First Published on September 27, 2005; doi:10.1074/jbc.M503320200 [Abstract] [Full Text] [PDF]

Dong-Hyun Lee, Seung-Gi Jin, Sheng Cai, Yuan Chen, Gerd P. Pfeifer, and Timothy R. O'Connor: Repair of Methylation Damage in DNA and RNA by Mammalian AlkB Homologues
J. Biol. Chem. 2005 280: 39448-39459. First Published on September 20, 2005; doi:10.1074/jbc.M509881200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shun-Fu Tseng, Chun-Yu Chang, Kou-Juey Wu, and Shu-Chun Teng: Importin KPNA2 Is Required for Proper Nuclear Localization and Multiple Functions of NBS1
J. Biol. Chem. 2005 280: 39594-39600. First Published on September 27, 2005; doi:10.1074/jbc.M508425200 [Abstract] [Full Text] [PDF]

Jae Wan Lee, Rika Kusumoto, Kevin M. Doherty, Guang-Xin Lin, Wangyong Zeng, Wen-Hsing Cheng, Cayetano von Kobbe, Robert M. Brosh, Jr., Jin-Shan Hu, and Vilhelm A. Bohr: Modulation of Werner Syndrome Protein Function by a Single Mutation in the Conserved RecQ Domain
J. Biol. Chem. 2005 280: 39627-39636. First Published on September 7, 2005; doi:10.1074/jbc.M506112200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Melissa I. Niesen, Aaron R. Osborne, Hua Yang, Shipra Rastogi, Srikumar Chellappan, Jin Q. Cheng, Jeremy M. Boss, and George Blanck: Activation of a Methylated Promoter Mediated by a Sequence-specific DNA-binding Protein, RFX
J. Biol. Chem. 2005 280: 38914-38922. First Published on September 15, 2005; doi:10.1074/jbc.M504633200 [Abstract] [Full Text] [PDF]

Sungman Park, Donghwa Kim, Satoshi Kaneko, Kristen M. Szewczyk, Santo V. Nicosia, Hua Yu, Richard Jove, and Jin Q. Cheng: Molecular Cloning and Characterization of the Human AKT1 Promoter Uncovers Its Up-regulation by the Src/Stat3 Pathway
J. Biol. Chem. 2005 280: 38932-38941. First Published on September 20, 2005; doi:10.1074/jbc.M504011200 [Abstract] [Full Text] [PDF]

Jinxin Gao, Asiya A. Gusa, June R. Scott, and Gordon Churchward: Binding of the Global Response Regulator Protein CovR to the sag Promoter of Streptococcus pyogenes Reveals a New Mode of CovR-DNA Interaction
J. Biol. Chem. 2005 280: 38948-38956. First Published on September 20, 2005; doi:10.1074/jbc.M506121200 [Abstract] [Full Text] [PDF]

Patrick G. Gallagher, Robert I. Liem, Ellice Wong, Mitchell J. Weiss, and David M. Bodine: GATA-1 and Oct-1 Are Required for Expression of the Human ${alpha}$ -Hemoglobin-stabilizing Protein Gene
J. Biol. Chem. 2005 280: 39016-39023. First Published on September 25, 2005; doi:10.1074/jbc.M506062200 [Abstract] [Full Text] [PDF]

Rutao Cui, Thi T. Nguyen, Joseph H. Taube, Sabrina A. Stratton, Miriam H. Feuerman, and Michelle Craig Barton: Family Members p53 and p73 Act Together in Chromatin Modification and Direct Repression of ${alpha}$ -Fetoprotein Transcription
J. Biol. Chem. 2005 280: 39152-39160. First Published on October 2, 2005; doi:10.1074/jbc.M504655200 [Abstract] [Full Text] [PDF]

Lei Gao, Sze-Wah Tse, Christopher Conrad, and Athena Andreadis: Saitohin, Which Is Nested in the tau Locus and Confers Allele-specific Susceptibility to Several Neurodegenerative Diseases, Interacts with Peroxiredoxin 6
J. Biol. Chem. 2005 280: 39268-39272. First Published on September 26, 2005; doi:10.1074/jbc.M506116200 [Abstract] [Full Text] [PDF]

Sunil C. Kaul, Satoshi Aida, Tomoko Yaguchi, Kamaljit Kaur, and Renu Wadhwa: Activation of Wild Type p53 Function by Its Mortalin-binding, Cytoplasmically Localizing Carboxyl Terminus Peptides
J. Biol. Chem. 2005 280: 39373-39379. First Published on September 21, 2005; doi:10.1074/jbc.M500022200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Christian Toft Madsen, Lene Jakobsen, Karolina Buriánková, Florence Doucet-Populaire, Jean-Luc Pernodet, and Stephen Douthwaite: Methyltransferase Erm(37) Slips on rRNA to Confer Atypical Resistance in Mycobacterium tuberculosis
J. Biol. Chem. 2005 280: 38942-38947. First Published on September 20, 2005; doi:10.1074/jbc.M505727200 [Abstract] [Full Text] [PDF]

John W. Pham and Erik J. Sontheimer: Molecular Requirements for RNA-induced Silencing Complex Assembly in the Drosophila RNA Interference Pathway
J. Biol. Chem. 2005 280: 39278-39283. First Published on September 22, 2005; doi:10.1074/jbc.M509202200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Tunda Hidvegi, Bela Z. Schmidt, Pamela Hale, and David H. Perlmutter: Accumulation of Mutant ${alpha}$ ₁-Antitrypsin Z in the Endoplasmic Reticulum Activates Caspases-4 and -12, NF ${kappa}$ B, and BAP31 but Not the Unfolded Protein Response
J. Biol. Chem. 2005 280: 39002-39015. First Published on September 23, 2005; doi:10.1074/jbc.M508652200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bonnie K. Baxter, Hagai Abeliovich, Xin Zhang, Aline G. Stirling, Alma L. Burlingame, and David S. Goldfarb: Atg19p Ubiquitination and the Cytoplasm to Vacuole Trafficking Pathway in Yeast
J. Biol. Chem. 2005 280: 39067-39076. First Published on September 26, 2005; doi:10.1074/jbc.M508064200 [Abstract] [Full Text] [PDF]

Akiko Hagiya, Takao Naganuma, Yasushi Maki, Jun Ohta, Yukiko Tohkairin, Tomomi Shimizu, Takaomi Nomura, Akira Hachimori, and Toshio Uchiumi: A Mode of Assembly of P0, P1, and P2 Proteins at the GTPase-associated Center in Animal Ribosome: IN VITRO ANALYSES WITH P0 TRUNCATION MUTANTS
J. Biol. Chem. 2005 280: 39193-39199. First Published on September 27, 2005; doi:10.1074/jbc.M506050200 [Abstract] [Full Text] [PDF]

Colin Hanfrey, Katherine A. Elliott, Marina Franceschetti, Melinda J. Mayer, Crista Illingworth, and Anthony J. Michael: A Dual Upstream Open Reading Frame-based Autoregulatory Circuit Controlling Polyamine-responsive Translation
J. Biol. Chem. 2005 280: 39229-39237. First Published on September 21, 2005; doi:10.1074/jbc.M509340200 [Abstract] [Full Text] [PDF]

Peter Krawitz, Christof Haffner, Regina Fluhrer, Harald Steiner, Bettina Schmid, and Christian Haass: Differential Localization and Identification of a Critical Aspartate Suggest Non-redundant Proteolytic Functions of the Presenilin Homologues SPPL2b and SPPL3
J. Biol. Chem. 2005 280: 39515-39523. First Published on July 5, 2005; doi:10.1074/jbc.M501645200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

George Hajishengallis, Pukar Ratti, and Evlambia Harokopakis: Peptide Mapping of Bacterial Fimbrial Epitopes Interacting with Pattern Recognition Receptors
J. Biol. Chem. 2005 280: 38902-38913. First Published on August 29, 2005; doi:10.1074/jbc.M507326200 [Abstract] [Full Text] [PDF]

Mário T. Murakami and Raghuvir K. Arni: Thrombomodulin-independent Activation of Protein C and Specificity of Hemostatically Active Snake Venom Serine Proteinases: CRYSTAL STRUCTURES OF NATIVE AND INHIBITED AGKISTRODON CONTORTRIX CONTORTRIX PROTEIN C ACTIVATOR
J. Biol. Chem. 2005 280: 39309-39315. First Published on September 14, 2005; doi:10.1074/jbc.M508502200 [Abstract] [Full Text] [PDF]

Roshan Kukreja and BalRam Singh: Biologically Active Novel Conformational State of Botulinum, the Most Poisonous Poison
J. Biol. Chem. 2005 280: 39346-39352. First Published on September 22, 2005; doi:10.1074/jbc.M508463200 [Abstract] [Full Text] [PDF]

Michael L. Oldham, Alan R. Brash, and Marcia E. Newcomer: Insights from the X-ray Crystal Structure of Coral 8R-Lipoxygenase: CALCIUM ACTIVATION VIA A C2-LIKE DOMAIN AND A STRUCTURAL BASIS OF PRODUCT CHIRALITY
J. Biol. Chem. 2005 280: 39545-39552. First Published on September 14, 2005; doi:10.1074/jbc.M506675200 [Abstract] [Full Text] [PDF]

Deanne M. Compaan, Lino C. Gonzalez, Irene Tom, Kelly M. Loyet, Dan Eaton, and Sarah G. Hymowitz: Attenuating Lymphocyte Activity: THE CRYSTAL STRUCTURE OF THE BTLA-HVEM COMPLEX
J. Biol. Chem. 2005 280: 39553-39561. First Published on September 16, 2005; doi:10.1074/jbc.M507629200 [Abstract] [Full Text] [PDF]

Xianrong Guo, You Li, Kuan Peng, Yunfei Hu, Congmin Li, Bin Xia, and Changwen Jin: Solution Structures and Backbone Dynamics of Arsenate Reductase from Bacillus subtilis: REVERSIBLE CONFORMATIONAL SWITCH ASSOCIATED WITH ARSENATE REDUCTION
J. Biol. Chem. 2005 280: 39601-39608. First Published on September 28, 2005; doi:10.1074/jbc.M508132200 [Abstract] [Full Text] [PDF]

Seiji Negoro, Taku Ohki, Naoki Shibata, Nobuhiro Mizuno, Yoshiaki Wakitani, Junya Tsurukame, Keiji Matsumoto, Ichitaro Kawamoto, Masahiro Takeo, and Yoshiki Higuchi: X-ray Crystallographic Analysis of 6-Aminohexanoate-Dimer Hydrolase: MOLECULAR BASIS FOR THE BIRTH OF A NYLON OLIGOMER-DEGRADING ENZYME
J. Biol. Chem. 2005 280: 39644-39652. First Published on September 14, 2005; doi:10.1074/jbc.M505946200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Vijayalaxmi Nalavadi, Miklós Nyitrai, Cristina Bertolini, Nancy Adamek, Michael A. Geeves, and Martin Bähler: Kinetic Mechanism of Myosin IXB and the Contributions of Two Class IX-specific Regions
J. Biol. Chem. 2005 280: 38957-38968. First Published on September 22, 2005; doi:10.1074/jbc.M507161200 [Abstract] [Full Text] [PDF]

Amnon Hizi and Henry L. Levin: The Integrase of the Long Terminal Repeat-Retrotransposon Tf1 Has a Chromodomain That Modulates Integrase Activities
J. Biol. Chem. 2005 280: 39086-39094. First Published on September 27, 2005; doi:10.1074/jbc.M506363200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shigeyuki Kawai, Chikako Fukuda, Takako Mukai, and Kousaku Murata: MJ0917 in Archaeon Methanococcus jannaschii Is a Novel NADP Phosphatase/NAD Kinase
J. Biol. Chem. 2005 280: 39200-39207. First Published on September 28, 2005; doi:10.1074/jbc.M506426200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mauro Tiso, David W. Konas, Koustubh Panda, Elsa D. Garcin, Manisha Sharma, Elizabeth D. Getzoff, and Dennis J. Stuehr: C-terminal Tail Residue Arg¹⁴⁰⁰ Enables NADPH to Regulate Electron Transfer in Neuronal Nitric-oxide Synthase
J. Biol. Chem. 2005 280: 39208-39219. First Published on September 8, 2005; doi:10.1074/jbc.M507775200 [Abstract] [Full Text] [PDF]

George Kukolj, Graham A. McGibbon, Ginette McKercher, Martin Marquis, Sylvain Lefèbvre, Louise Thauvette, Jean Gauthier, Sylvie Goulet, Marc-André Poupart, and Pierre L. Beaulieu: Binding Site Characterization and Resistance to a Class of Non-nucleoside Inhibitors of the Hepatitis C Virus NS5B Polymerase
J. Biol. Chem. 2005 280: 39260-39267. First Published on September 27, 2005; doi:10.1074/jbc.M506407200 [Abstract] [Full Text] [PDF]

Fiona J. Warner, Rebecca A. Lew, A. Ian Smith, Daniel W. Lambert, Nigel M. Hooper, and Anthony J. Turner: Angiotensin-converting Enzyme 2 (ACE2), But Not ACE, Is Preferentially Localized to the Apical Surface of Polarized Kidney Cells
J. Biol. Chem. 2005 280: 39353-39362. First Published on September 15, 2005; doi:10.1074/jbc.M508914200 [Abstract] [Full Text] [PDF]

Myth T. S. Mok and Michael R. Edwards: Kinetic and Physical Characterization of the Inducible UDP-N-acetylglucosamine Pyrophosphorylase from Giardia intestinalis
J. Biol. Chem. 2005 280: 39363-39372. First Published on September 16, 2005; doi:10.1074/jbc.M509209200 [Abstract] [Full Text] [PDF]

Felicity K. Kerr, Grace O'Brien, Noelene S. Quinsey, James C. Whisstock, Sarah Boyd, Maria Garcia de la Banda, Dion Kaiserman, Antony Y. Matthews, Phillip I. Bird, and Robert N. Pike: Elucidation of the Substrate Specificity of the C1s Protease of the Classical Complement Pathway
J. Biol. Chem. 2005 280: 39510-39514. First Published on September 16, 2005; doi:10.1074/jbc.M506131200 [Abstract] [Full Text] [PDF]

Shinpei Katou, Eri Karita, Hiromoto Yamakawa, Shigemi Seo, Ichiro Mitsuhara, Kazuyuki Kuchitsu, and Yuko Ohashi: Catalytic Activation of the Plant MAPK Phosphatase NtMKP1 by Its Physiological Substrate Salicylic Acid-induced Protein Kinase but Not by Calmodulins
J. Biol. Chem. 2005 280: 39569-39581. First Published on September 22, 2005; doi:10.1074/jbc.M508115200 [Abstract] [Full Text] [PDF]

Arnon Henn and Enrique M. De La Cruz: Vertebrate Myosin VIIb Is a High Duty Ratio Motor Adapted for Generating and Maintaining Tension
J. Biol. Chem. 2005 280: 39665-39676. First Published on September 26, 2005; doi:10.1074/jbc.M507667200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Nobuharu Fujii, Michael F. Hirshman, Erin M. Kane, Richard C. Ho, Lauren E. Peter, Matthew M. Seifert, and Laurie J. Goodyear: AMP-activated Protein Kinase ${alpha}$ 2 Activity Is Not Essential for Contraction- and Hyperosmolarity-induced Glucose Transport in Skeletal Muscle
J. Biol. Chem. 2005 280: 39033-39041. First Published on September 26, 2005; doi:10.1074/jbc.M504208200 [Abstract] [Full Text] [PDF]

Lynette Cegelski and Jacob Schaefer: Glycine Metabolism in Intact Leaves by in Vivo 13C and ¹⁵N Labeling
J. Biol. Chem. 2005 280: 39238-39245. First Published on September 13, 2005; doi:10.1074/jbc.M507053200 [Abstract] [Full Text] [PDF]

Sonya G. Fonseca, Mariko Fukuma, Kathryn L. Lipson, Linh X. Nguyen, Jenny R. Allen, Yoshitomo Oka, and Fumihiko Urano: WFS1 Is a Novel Component of the Unfolded Protein Response and Maintains Homeostasis of the Endoplasmic Reticulum in Pancreatic ${beta}$ -Cells
J. Biol. Chem. 2005 280: 39609-39615. First Published on September 29, 2005; doi:10.1074/jbc.M507426200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Mahendrasingh Ramjeet, Vincent Deslandes, Frank St. Michael, Andrew D. Cox, Marylène Kobisch, Marcelo Gottschalk, and Mario Jacques: Truncation of the Lipopolysaccharide Outer Core Affects Susceptibility to Antimicrobial Peptides and Virulence of Actinobacillus pleuropneumoniae Serotype 1
J. Biol. Chem. 2005 280: 39104-39114. First Published on September 27, 2005; doi:10.1074/jbc.M502852200 [Abstract] [Full Text] [PDF]

Shiori Ohtake, Koji Kimata, and Osami Habuchi: Recognition of Sulfation Pattern of Chondroitin Sulfate by Uronosyl 2-O-Sulfotransferase
J. Biol. Chem. 2005 280: 39115-39123. First Published on September 27, 2005; doi:10.1074/jbc.M508816200 [Abstract] [Full Text] [PDF]

Tomoo Ohashi and Harold P. Erickson: Domain Unfolding Plays a Role in Superfibronectin Formation
J. Biol. Chem. 2005 280: 39143-39151. First Published on September 29, 2005; doi:10.1074/jbc.M509082200 [Abstract] [Full Text] [PDF]

Kazuya Hirano, Yuichi Miki, Yuriko Hirai, Rumi Sato, Takashi Itoh, Akiko Hayashi, Masahiro Yamanaka, Shigetoshi Eda, and Masatoshi Beppu: A Multifunctional Shuttling Protein Nucleolin Is a Macrophage Receptor for Apoptotic Cells
J. Biol. Chem. 2005 280: 39284-39293. First Published on August 31, 2005; doi:10.1074/jbc.M505275200 [Abstract] [Full Text] [PDF]

Shu Q. Liu, Paul K. Alkema, Christopher Tieché, Brandon J. Tefft, Diana Z. Liu, Yan Chun Li, Bauer E. Sumpio, Joseph A. Caprini, and Mary Paniagua: Negative Regulation of Monocyte Adhesion to Arterial Elastic Laminae by Signal Regulatory Protein ${alpha}$ and Src Homology 2 Domain-containing Protein-Tyrosine Phosphatase-1
J. Biol. Chem. 2005 280: 39294-39301. First Published on September 13, 2005; doi:10.1074/jbc.M503866200 [Abstract] [Full Text] [PDF]

ChengJun Sun and J. Herbert Waite: Mapping Chemical Gradients within and along a Fibrous Structural Tissue, Mussel Byssal Threads
J. Biol. Chem. 2005 280: 39332-39336. First Published on September 15, 2005; doi:10.1074/jbc.M508674200 [Abstract] [Full Text] [PDF]

Aymeric de Parseval, Michael D. Bobardt, Anju Chatterji, Udayan Chatterji, John H. Elder, Guido David, Susan Zolla-Pazner, Michael Farzan, Tun-Hou Lee, and Philippe A. Gallay: A Highly Conserved Arginine in gp120 Governs HIV-1 Binding to Both Syndecans and CCR5 via Sulfated Motifs
J. Biol. Chem. 2005 280: 39493-39504. First Published on September 12, 2005; doi:10.1074/jbc.M504233200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Kei-ichiro Okuhira, Michael L. Fitzgerald, David A. Sarracino, Jennifer J. Manning, Susan A. Bell, Julie L. Goss, and Mason W. Freeman: Purification of ATP-binding Cassette Transporter A1 and Associated Binding Proteins Reveals the Importance of ${beta}$ 1-Syntrophin in Cholesterol Efflux
J. Biol. Chem. 2005 280: 39653-39664. First Published on September 28, 2005; doi:10.1074/jbc.M510187200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Sandra Deitermann, Grit Sophie Sprie, and Hans-Georg Koch: A Dual Function for SecA in the Assembly of Single Spanning Membrane Proteins in Escherichia coli
J. Biol. Chem. 2005 280: 39077-39085. First Published on September 26, 2005; doi:10.1074/jbc.M509647200 [Abstract] [Full Text] [PDF]

Leonard Dode, Jens Peter Andersen, Luc Raeymaekers, Ludwig Missiaen, Bente Vilsen, and Frank Wuytack: Functional Comparison between Secretory Pathway Ca²⁺/Mn²⁺-ATPase (SPCA) 1 and Sarcoplasmic Reticulum Ca²⁺-ATPase (SERCA) 1 Isoforms by Steady-state and Transient Kinetic Analyses
J. Biol. Chem. 2005 280: 39124-39134. First Published on September 28, 2005; doi:10.1074/jbc.M506181200 [Abstract] [Full Text] [PDF]

Mitsunori Fukuda, Akane Imai, Tomoko Nashida, and Hiromi Shimomura: Slp4-a/Granuphilin-a Interacts with Syntaxin-2/3 in a Munc18-2-dependent Manner
J. Biol. Chem. 2005 280: 39175-39184. First Published on September 26, 2005; doi:10.1074/jbc.M505759200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zheng Zhang, Haruhisa Okawa, Yuanyuan Wang, and Emily R. Liman: Phosphatidylinositol 4,5-Bisphosphate Rescues TRPM4 Channels from Desensitization
J. Biol. Chem. 2005 280: 39185-39192. First Published on September 26, 2005; doi:10.1074/jbc.M506965200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Takashi Tsuboi and Mitsunori Fukuda: The C2B Domain of Rabphilin Directly Interacts with SNAP-25 and Regulates the Docking Step of Dense Core Vesicle Exocytosis in PC12 Cells
J. Biol. Chem. 2005 280: 39253-39259. First Published on October 3, 2005; doi:10.1074/jbc.M507173200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Emma Sparr, Walter L. Ash, Petr V. Nazarov, Dirk T. S. Rijkers, Marcus A. Hemminga, D. Peter Tieleman, and J. Antoinette Killian: Self-association of Transmembrane ${alpha}$ -Helices in Model Membranes: IMPORTANCE OF HELIX ORIENTATION AND ROLE OF HYDROPHOBIC MISMATCH
J. Biol. Chem. 2005 280: 39324-39331. First Published on September 15, 2005; doi:10.1074/jbc.M502810200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Robert F. Jacob and R. Preston Mason: Lipid Peroxidation Induces Cholesterol Domain Formation in Model Membranes
J. Biol. Chem. 2005 280: 39380-39387. First Published on September 28, 2005; doi:10.1074/jbc.M507587200 [Abstract] [Full Text] [PDF]

Joshua T. Wolfe, Bryan A. Krantz, G. Jonah A. Rainey, John A. T. Young, and R. John Collier: Whole-cell Voltage Clamp Measurements of Anthrax Toxin Pore Current
J. Biol. Chem. 2005 280: 39417-39422. First Published on September 23, 2005; doi:10.1074/jbc.M509049200 [Abstract] [Full Text] [PDF]

Stéphanie Thebault, Loïc Lemonnier, Gabriel Bidaux, Matthieu Flourakis, Alexis Bavencoffe, Dimitri Gordienko, Morad Roudbaraki, Philippe Delcourt, Yuri Panchin, Yaroslav Shuba, Roman Skryma, and Natalia Prevarskaya: Novel Role of Cold/Menthol-sensitive Transient Receptor Potential Melastatine Family Member 8 (TRPM8) in the Activation of Store-operated Channels in LNCaP Human Prostate Cancer Epithelial Cells
J. Biol. Chem. 2005 280: 39423-39435. First Published on September 20, 2005; doi:10.1074/jbc.M503544200 [Abstract] [Full Text] [PDF]

Mike Mueckler and Carol Makepeace: Cysteine-scanning Mutagenesis and Substituted Cysteine Accessibility Analysis of Transmembrane Segment 4 of the Glut1 Glucose Transporter
J. Biol. Chem. 2005 280: 39562-39568. First Published on September 19, 2005; doi:10.1074/jbc.M509050200 [Abstract] [Full Text] [PDF]

Rahim Habibian, Judith Dzioba, Jeannie Barrett, Michael Y. Galperin, Peter C. Loewen, and Pavel Dibrov: Functional Analysis of Conserved Polar Residues in Vc-NhaD, Na⁺/H⁺ Antiporter of Vibrio cholerae
J. Biol. Chem. 2005 280: 39637-39643. First Published on September 26, 2005; doi:10.1074/jbc.M509328200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Thomas Piechulek, Tobias Rehlen, Claudia Walliser, Petra Vatter, Barbara Moepps, and Peter Gierschik: Isozyme-specific Stimulation of Phospholipase C- ${gamma}$ ₂ by Rac GTPases
J. Biol. Chem. 2005 280: 38923-38931. First Published on September 19, 2005; doi:10.1074/jbc.M509396200 [Abstract] [Full Text] [PDF] [Summary]

Hai-Yan Qi and James H. Shelhamer: Toll-like Receptor 4 Signaling Regulates Cytosolic Phospholipase A₂ Activation and Lipid Generation in Lipopolysaccharide-stimulated Macrophages
J. Biol. Chem. 2005 280: 38969-38975. First Published on September 21, 2005; doi:10.1074/jbc.M509352200 [Abstract] [Full Text] [PDF]

Ying Liu, Kazuyuki Furuta, Reiko Teshima, Naritoshi Shirata, Yukihiko Sugimoto, Atsushi Ichikawa, and Satoshi Tanaka: Critical Role of Protein Kinase C ${beta}$ II in Activation of Mast Cells by Monomeric IgE
J. Biol. Chem. 2005 280: 38976-38981. First Published on September 22, 2005; doi:10.1074/jbc.M506351200 [Abstract] [Full Text] [PDF]

Anatilde M. Gonzalez-Guerrico and Marcelo G. Kazanietz: Phorbol Ester-induced Apoptosis in Prostate Cancer Cells via Autocrine Activation of the Extrinsic Apoptotic Cascade: A KEY ROLE FOR PROTEIN KINASE C ${delta}$
J. Biol. Chem. 2005 280: 38982-38991. First Published on September 23, 2005; doi:10.1074/jbc.M506767200 [Abstract] [Full Text] [PDF]

Ivan Azarov, Kris T. Huang, Swati Basu, Mark T. Gladwin, Neil Hogg, and Daniel B. Kim-Shapiro: Nitric Oxide Scavenging by Red Blood Cells as a Function of Hematocrit and Oxygenation
J. Biol. Chem. 2005 280: 39024-39032. First Published on September 25, 2005; doi:10.1074/jbc.M509045200 [Abstract] [Full Text] [PDF]

Guoquan Liu and Tatyana A. Voyno-Yasenetskaya: Radixin Stimulates Rac1 and Ca²⁺/Calmodulin-dependent Kinase, CaMKII: CROSS-TALK WITH G ${alpha}$ ₁₃ SIGNALING
J. Biol. Chem. 2005 280: 39042-39049. First Published on September 26, 2005; doi:10.1074/jbc.M504341200 [Abstract] [Full Text] [PDF]

Sriparna Bagchi, Zhongji Liao, Fernando A. Gonzalez, Nataliya E. Chorna, Cheikh I. Seye, Gary A. Weisman, and Laurie Erb: The P2Y₂ Nucleotide Receptor Interacts with ${alpha}$ _v Integrins to Activate G_o and Induce Cell Migration
J. Biol. Chem. 2005 280: 39050-39057. First Published on September 26, 2005; doi:10.1074/jbc.M504819200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kyungmi Yang, Jeong Hak Kim, Hae Jong Kim, In-Sung Park, Ick Young Kim, and Beom-Seok Yang: Tyrosine 740 Phosphorylation of Discoidin Domain Receptor 2 by Src Stimulates Intramolecular Autophosphorylation and Shc Signaling Complex Formation
J. Biol. Chem. 2005 280: 39058-39066. First Published on September 26, 2005; doi:10.1074/jbc.M506921200 [Abstract] [Full Text] [PDF]

Alexander Staruschenko, Oleh Pochynyuk, and James D. Stockand: Regulation of Epithelial Na⁺ Channel Activity by Conserved Serine/Threonine Switches within Sorting Signals
J. Biol. Chem. 2005 280: 39161-39167. First Published on October 3, 2005; doi:10.1074/jbc.M509608200 [Abstract] [Full Text] [PDF]

Ryan Hambleton, Judith Krall, Eliso Tikishvili, Matthew Honeggar, Faiyaz Ahmad, Vincent C. Manganiello, and Matthew A. Movsesian: Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3 and Their Contribution to cAMP Hydrolytic Activity in Subcellular Fractions of Human Myocardium
J. Biol. Chem. 2005 280: 39168-39174. First Published on September 19, 2005; doi:10.1074/jbc.M506760200 [Abstract] [Full Text] [PDF]

Alexander I. Chernyavsky, Juan Arredondo, Evert Karlsson, Ignaz Wessler, and Sergei A. Grando: The Ras/Raf-1/MEK1/ERK Signaling Pathway Coupled to Integrin Expression Mediates Cholinergic Regulation of Keratinocyte Directional Migration
J. Biol. Chem. 2005 280: 39220-39228. First Published on September 8, 2005; doi:10.1074/jbc.M504407200 [Abstract] [Full Text] [PDF]

Hiroyuki Niida, Shinji Tsuge, Yuko Katsuno, Akimitsu Konishi, Naoki Takeda, and Makoto Nakanishi: Depletion of Chk1 Leads to Premature Activation of Cdc2-cyclin B and Mitotic Catastrophe
J. Biol. Chem. 2005 280: 39246-39252. First Published on September 13, 2005; doi:10.1074/jbc.M505009200 [Abstract] [Full Text] [PDF]

Robin D. Lester, Minji Jo, W. Marie Campana, and Steven L. Gonias: Erythropoietin Promotes MCF-7 Breast Cancer Cell Migration by an ERK/Mitogen-activated Protein Kinase-dependent Pathway and Is Primarily Responsible for the Increase in Migration Observed in Hypoxia
J. Biol. Chem. 2005 280: 39273-39277. First Published on October 5, 2005; doi:10.1074/jbc.M509446200 [Abstract] [Full Text] [PDF]

A. J. Robison, Ryan K. Bartlett, Martha A. Bass, and Roger J. Colbran: Differential Modulation of Ca²⁺/Calmodulin-dependent Protein Kinase II Activity by Regulated Interactions with N-Methyl-D-aspartate Receptor NR2B Subunits and ${alpha}$ -Actinin
J. Biol. Chem. 2005 280: 39316-39323. First Published on September 19, 2005; doi:10.1074/jbc.M508189200 [Abstract] [Full Text] [PDF]

Jake A. Kushner, Laura Simpson, Lynn M. Wartschow, Shaodong Guo, Matthew M. Rankin, Ramon Parsons, and Morris F. White: Phosphatase and Tensin Homolog Regulation of Islet Growth and Glucose Homeostasis
J. Biol. Chem. 2005 280: 39388-39393. First Published on September 16, 2005; doi:10.1074/jbc.M504155200 [Abstract] [Full Text] [PDF]

El-Sayed Akool, Anke Doller, Roswitha Müller, Paul Gutwein, Cuiyan Xin, Andrea Huwiler, Josef Pfeilschifter, and Wolfgang Eberhardt: Nitric Oxide Induces TIMP-1 Expression by Activating the Transforming Growth Factor ${beta}$ -Smad Signaling Pathway
J. Biol. Chem. 2005 280: 39403-39416. First Published on September 23, 2005; doi:10.1074/jbc.M504140200 [Abstract] [Full Text] [PDF]

Debabrata Mandal, Arindam Mazumder, Pradeep Das, Manikuntala Kundu, and Joyoti Basu: Fas-, Caspase 8-, and Caspase 3-dependent Signaling Regulates the Activity of the Aminophospholipid Translocase and Phosphatidylserine Externalization in Human Erythrocytes
J. Biol. Chem. 2005 280: 39460-39467. First Published on September 22, 2005; doi:10.1074/jbc.M506928200 [Abstract] [Full Text] [PDF]

Owen J. T. McCarty, Mark K. Larson, Jocelyn M. Auger, Neena Kalia, Ben T. Atkinson, Andrew C. Pearce, Sandra Ruf, Robert B. Henderson, Victor L. J. Tybulewicz, Laura M. Machesky, and Steve P. Watson: Rac1 Is Essential for Platelet Lamellipodia Formation and Aggregate Stability under Flow
J. Biol. Chem. 2005 280: 39474-39484. First Published on September 29, 2005; doi:10.1074/jbc.M504672200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yumin Hu, Daniel G. Rosen, Yan Zhou, Li Feng, Gong Yang, Jinsong Liu, and Peng Huang: Mitochondrial Manganese-Superoxide Dismutase Expression in Ovarian Cancer: ROLE IN CELL PROLIFERATION AND RESPONSE TO OXIDATIVE STRESS
J. Biol. Chem. 2005 280: 39485-39492. First Published on September 22, 2005; doi:10.1074/jbc.M503296200 [Abstract] [Full Text] [PDF]

Dos D. Sarbassov and David M. Sabatini: Redox Regulation of the Nutrient-sensitive Raptor-mTOR Pathway and Complex
J. Biol. Chem. 2005 280: 39505-39509. First Published on September 23, 2005; doi:10.1074/jbc.M506096200 [Abstract] [Full Text] [PDF]

Tatsuya Ozawa, Norie Araki, Shunji Yunoue, Hiroshi Tokuo, Liping Feng, Siriporn Patrakitkomjorn, Toshihiro Hara, Yasuko Ichikawa, Kunio Matsumoto, Kiyotaka Fujii, and Hideyuki Saya: The Neurofibromatosis Type 1 Gene Product Neurofibromin Enhances Cell Motility by Regulating Actin Filament Dynamics via the Rho-ROCK-LIMK2-Cofilin Pathway
J. Biol. Chem. 2005 280: 39524-39533. First Published on September 16, 2005; doi:10.1074/jbc.M503707200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ramandeep Rattan, Shailendra Giri, Avtar K. Singh, and Inderjit Singh: 5-Aminoimidazole-4-carboxamide-1- ${beta}$ -D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase
J. Biol. Chem. 2005 280: 39582-39593. First Published on September 21, 2005; doi:10.1074/jbc.M507443200 [Abstract] [Full Text] [PDF]

Yves Gorin, Karen Block, James Hernandez, Basant Bhandari, Brent Wagner, Jeffrey L. Barnes, and Hanna E. Abboud: Nox4 NAD(P)H Oxidase Mediates Hypertrophy and Fibronectin Expression in the Diabetic Kidney
J. Biol. Chem. 2005 280: 39616-39626. First Published on August 31, 2005; doi:10.1074/jbc.M502412200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Juan I. Diaz-Hernandez, Angeles Almeida, Maria Delgado-Esteban, Emilio Fernandez, and Juan P. Bolaños: Knockdown of Glutamate-Cysteine Ligase by Small Hairpin RNA Reveals That Both Catalytic and Modulatory Subunits Are Essential for the Survival of Primary Neurons
J. Biol. Chem. 2005 280: 38992-39001. First Published on September 23, 2005; doi:10.1074/jbc.M507065200 [Abstract] [Full Text] [PDF]

Sophia Smida Rezgui, Stéphane Vassilopoulos, Julie Brocard, Jean Claude Platel, Alexandre Bouron, Christophe Arnoult, Sarah Oddoux, Luis Garcia, Michel De Waard, and Isabelle Marty: Triadin (Trisk 95) Overexpression Blocks Excitation-Contraction Coupling in Rat Skeletal Myotubes
J. Biol. Chem. 2005 280: 39302-39308. First Published on September 21, 2005; doi:10.1074/jbc.M506566200 [Abstract] [Full Text] [PDF]

Guosheng Xiang, Tetsunori Seki, Michael D. Schuster, Piotr Witkowski, Andrew J. Boyle, Fiona See, Timothy P. Martens, Alfred Kocher, Hugo Sondermeijer, Henry Krum, and Silviu Itescu: Catalytic Degradation of Vitamin D Up-regulated Protein 1 mRNA Enhances Cardiomyocyte Survival and Prevents Left Ventricular Remodeling after Myocardial Ischemia
J. Biol. Chem. 2005 280: 39394-39402. First Published on September 19, 2005; doi:10.1074/jbc.M502966200 [Abstract] [Full Text] [PDF]

Keiko Shimono, Yohei Shimono, Kaoru Shimokata, Naoki Ishiguro, and Masahide Takahashi: Microspherule Protein 1, Mi-2 ${beta}$ , and RET Finger Protein Associate in the Nucleolus and Up-regulate Ribosomal Gene Transcription
J. Biol. Chem. 2005 280: 39436-39447. First Published on September 26, 2005; doi:10.1074/jbc.M507356200 [Abstract] [Full Text] [PDF]

Maki Kawai-Yamada, Yusuke Saito, Lihua Jin, Taro Ogawa, Kyung-Min Kim, Li-Hua Yu, Yoshiko Tone, Aiko Hirata, Masaaki Umeda, and Hirofumi Uchimiya: A Novel Arabidopsis Gene Causes Bax-like Lethality in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 39468-39473. First Published on September 28, 2005; doi:10.1074/jbc.M509632200 [Abstract] [Full Text] [PDF]

Daihiko Hakuno, Tomosaburo Takahashi, Jan Lammerding, and Richard T. Lee: Focal Adhesion Kinase Signaling Regulates Cardiogenesis of Embryonic Stem Cells
J. Biol. Chem. 2005 280: 39534-39544. First Published on September 11, 2005; doi:10.1074/jbc.M505575200 [Abstract] [Full Text] [PDF] [Supplemental Data]