JBC -- Table of Contents (Dec 9 2005, 280, (49))

HOME

HELP

FEEDBACK

SUBSCRIPTIONS

Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Arthur Kornberg's Discovery of DNA Polymerase I
Enzymatic Synthesis of Deoxyribonucleic Acid. I. PREPARATION OF SUBSTRATES AND PARTIAL PURIFICATION OF AN ENZYME FROM ESCHERICHIA COLI (I. R. Lehman, Maurice J. Bessman, Ernest S. Simms, and Arthur Kornberg J. Biol. Chem. 233, 163-170)
Enzymatic Synthesis of Deoxyribonucleic Acid. II. GENERAL PROPERTIES OF THE REACTION (Maurice J. Bessman, I. R. Lehman, Ernest S. Simms, and Arthur Kornberg J. Biol. Chem. 233, 171-177)
J. Biol. Chem. 2005 280: e46. [Full Text]

Accelerated Publications:

Junghee Lee, Chun-Hyung Kim, David K. Simon, Lyaylya R. Aminova, Alexander Y. Andreyev, Yulia E. Kushnareva, Anne N. Murphy, Bonnie E. Lonze, Kwang-Soo Kim, David D. Ginty, Robert J. Ferrante, Hoon Ryu, and Rajiv R. Ratan: Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival
J. Biol. Chem. 2005 280: 40398-40401. First Published on October 5, 2005; doi:10.1074/jbc.C500140200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tomás Racek, Nikica Mise, Zhenpeng Li, Anja Stoll, and Brigitte M. Pützer: C-terminal p73 Isoforms Repress Transcriptional Activity of the Human Telomerase Reverse Transcriptase (hTERT) Promoter
J. Biol. Chem. 2005 280: 40402-40405. First Published on October 17, 2005; doi:10.1074/jbc.C500193200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Thale C. Jarvis, Amber A. Beaudry, James M. Bullard, Urs Ochsner, H. Garry Dallmann, and Charles S. McHenry: Discovery and Characterization of the Cryptic ${Psi}$ Subunit of the Pseudomonad DNA Replicase
J. Biol. Chem. 2005 280: 40465-40473. First Published on October 6, 2005; doi:10.1074/jbc.M508310200 [Abstract] [Full Text] [PDF]

Vandana Purohit, Mini Balakrishnan, Baek Kim, and Robert A. Bambara: Evidence That HIV-1 Reverse Transcriptase Employs the DNA 3' End-directed Primary/Secondary RNase H Cleavage Mechanism during Synthesis and Strand Transfer
J. Biol. Chem. 2005 280: 40534-40543. First Published on October 11, 2005; doi:10.1074/jbc.M507839200 [Abstract] [Full Text] [PDF]

Jingping Hu, Nadja C. de Souza-Pinto, Kazuhiro Haraguchi, Barbara A. Hogue, Pawel Jaruga, Marc M. Greenberg, Miral Dizdaroglu, and Vilhelm A. Bohr: Repair of Formamidopyrimidines in DNA Involves Different Glycosylases: ROLE OF THE OGG1, NTH1, AND NEIL1 ENZYMES
J. Biol. Chem. 2005 280: 40544-40551. First Published on October 11, 2005; doi:10.1074/jbc.M508772200 [Abstract] [Full Text] [PDF]

Janina Cramer and Tobias Restle: Pre-steady-state Kinetic Characterization of the DinB Homologue DNA Polymerase of Sulfolobus solfataricus
J. Biol. Chem. 2005 280: 40552-40558. First Published on October 12, 2005; doi:10.1074/jbc.M504481200 [Abstract] [Full Text] [PDF]

Nianxiang Zhang, Ramandeep Kaur, Xiaoyan Lu, Xi Shen, Lei Li, and Randy J. Legerski: The Pso4 mRNA Splicing and DNA Repair Complex Interacts with WRN for Processing of DNA Interstrand Cross-links
J. Biol. Chem. 2005 280: 40559-40567. First Published on October 12, 2005; doi:10.1074/jbc.M508453200 [Abstract] [Full Text] [PDF]

Yacob Gómez-Llorente, Ryan J. Fletcher, Xiaojiang S. Chen, José M. Carazo, and Carmen San Martín: Polymorphism and Double Hexamer Structure in the Archaeal Minichromosome Maintenance (MCM) Helicase from Methanobacterium thermoautotrophicum
J. Biol. Chem. 2005 280: 40909-40915. First Published on October 11, 2005; doi:10.1074/jbc.M509760200 [Abstract] [Full Text] [PDF]

Ming-Hui Lee, Yuan-Chih Chang, Eurie L. Hong, Jennifer Grubb, Chia-Seng Chang, Douglas K. Bishop, and Ting-Fang Wang: Calcium Ion Promotes Yeast Dmc1 Activity via Formation of Long and Fine Helical Filaments with Single-stranded DNA
J. Biol. Chem. 2005 280: 40980-40984. First Published on October 4, 2005; doi:10.1074/jbc.M505896200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Paul O. Hassa, Sandra S. Haenni, Christine Buerki, Nadja I. Meier, William S. Lane, Heather Owen, Monika Gersbach, Ralph Imhof, and Michael O. Hottiger: Acetylation of Poly(ADP-ribose) Polymerase-1 by p300/CREB-binding Protein Regulates Coactivation of NF- ${kappa}$ B-dependent Transcription
J. Biol. Chem. 2005 280: 40450-40464. First Published on October 4, 2005; doi:10.1074/jbc.M507553200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Julia Wennerhold, Andreas Krug, and Michael Bott: The AraC-type Regulator RipA Represses Aconitase and Other Iron Proteins from Corynebacterium under Iron Limitation and Is Itself Repressed by DtxR
J. Biol. Chem. 2005 280: 40500-40508. First Published on September 22, 2005; doi:10.1074/jbc.M508693200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kailash Gulshan, Sherry A. Rovinsky, Sean T. Coleman, and W. Scott Moye-Rowley: Oxidant-specific Folding of Yap1p Regulates Both Transcriptional Activation and Nuclear Localization
J. Biol. Chem. 2005 280: 40524-40533. First Published on October 11, 2005; doi:10.1074/jbc.M504716200 [Abstract] [Full Text] [PDF]

Qi Shen and Sylvia Christakos: The Vitamin D Receptor, Runx2, and the Notch Signaling Pathway Cooperate in the Transcriptional Regulation of Osteopontin
J. Biol. Chem. 2005 280: 40589-40598. First Published on September 29, 2005; doi:10.1074/jbc.M504166200 [Abstract] [Full Text] [PDF]

Sharon Yavrom, Li Chen, Shigang Xiong, Jiaohong Wang, Richard A. Rippe, and Hidekazu Tsukamoto: Peroxisome Proliferator-activated Receptor ${gamma}$ Suppresses Proximal ${alpha}$ 1(I) Collagen Promoter via Inhibition of p300-facilitated NF-I Binding to DNA in Hepatic Stellate Cells
J. Biol. Chem. 2005 280: 40650-40659. First Published on October 10, 2005; doi:10.1074/jbc.M510094200 [Abstract] [Full Text] [PDF]

Indrani Talukdar, Wioletta Szeszel-Fedorowicz, and Lisa M. Salati: Arachidonic Acid Inhibits the Insulin Induction of Glucose-6-phosphate Dehydrogenase via p38 MAP Kinase
J. Biol. Chem. 2005 280: 40660-40667. First Published on October 6, 2005; doi:10.1074/jbc.M505531200 [Abstract] [Full Text] [PDF]

Guo-Qing Tang, Rajiv P. Bandwar, and Smita S. Patel: Extended Upstream A-T Sequence Increases T7 Promoter Strength
J. Biol. Chem. 2005 280: 40707-40713. First Published on October 7, 2005; doi:10.1074/jbc.M508013200 [Abstract] [Full Text] [PDF]

Paolo Struffi and David N. Arnosti: Functional Interaction between the Drosophila Knirps Short Range Transcriptional Repressor and RPD3 Histone Deacetylase
J. Biol. Chem. 2005 280: 40757-40765. First Published on September 26, 2005; doi:10.1074/jbc.M506819200 [Abstract] [Full Text] [PDF]

Man Soo Choi, Min Chul Kim, Jae Hyuk Yoo, Byeong Cheol Moon, Sung Cheol Koo, Byung Ouk Park, Ju Huck Lee, Yoon Duck Koo, Hay Ju Han, Sang Yeol Lee, Woo Sik Chung, Chae Oh Lim, and Moo Je Cho: Isolation of a Calmodulin-binding Transcription Factor from Rice (Oryza sativa L.)
J. Biol. Chem. 2005 280: 40820-40831. First Published on September 28, 2005; doi:10.1074/jbc.M504616200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Andrey L. Karamyshev, Daniel J. Kelleher, Reid Gilmore, Arthur E. Johnson, Gunnar von Heijne, and IngMarie Nilsson: Mapping the Interaction of the STT3 Subunit of the Oligosaccharyl Transferase Complex with Nascent Polypeptide Chains
J. Biol. Chem. 2005 280: 40489-40493. First Published on October 10, 2005; doi:10.1074/jbc.M509168200 [Abstract] [Full Text] [PDF]

Celia Bonaventura, Gerald Godette, Robert Stevens, Michael Brenowitz, and Robert Henkens: Overproduction of ${alpha}$ Chains Provides a Proton-insensitive Component to the Bluefish Hemoglobin System
J. Biol. Chem. 2005 280: 40509-40514. First Published on September 15, 2005; doi:10.1074/jbc.M505353200 [Abstract] [Full Text] [PDF]

Gang Zheng and Yu-Chung Yang: Sumoylation and Acetylation Play Opposite Roles in the Transactivation of PLAG1 and PLAGL2
J. Biol. Chem. 2005 280: 40773-40781. First Published on October 5, 2005; doi:10.1074/jbc.M504334200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jörg Hinnerwisch, Brian G. Reid, Wayne A. Fenton, and Arthur L. Horwich: Roles of the N-domains of the ClpA Unfoldase in Binding Substrate Proteins and in Stable Complex Formation with the ClpP Protease
J. Biol. Chem. 2005 280: 40838-40844. First Published on October 5, 2005; doi:10.1074/jbc.M507879200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Jody M. Mason, Matthew J. Cliff, Richard B. Sessions, and Anthony R. Clarke: Low Energy Pathways and Non-native Interactions: THE INFLUENCE OF ARTIFICIAL DISULFIDE BRIDGES ON THE MECHANISM OF FOLDING
J. Biol. Chem. 2005 280: 40494-40499. First Published on October 10, 2005; doi:10.1074/jbc.M509281200 [Abstract] [Full Text] [PDF]

Qing Wang, Changcheng Song, Lauren Irizarry, Renming Dai, Xiaodong Zhang, and Chou-Chi H. Li: Multifunctional Roles of the Conserved Arg Residues in the Second Region of Homology of p97/Valosin-containing Protein
J. Biol. Chem. 2005 280: 40515-40523. First Published on October 10, 2005; doi:10.1074/jbc.M509636200 [Abstract] [Full Text] [PDF]

Gishanthi P. K. Marasinghe, Ian M. Sander, Brian Bennett, Gopalraj Periyannan, Ke-Wu Yang, Christopher A. Makaroff, and Michael W. Crowder: Structural Studies on a Mitochondrial Glyoxalase II
J. Biol. Chem. 2005 280: 40668-40675. First Published on October 14, 2005; doi:10.1074/jbc.M509748200 [Abstract] [Full Text] [PDF]

Libia Sanz, Run-Qiang Chen, Alicia Pérez, Rebeca Hilario, Paula Juárez, Cezary Marcinkiewicz, Daniel Monleón, Bernardo Celda, Yu-Liang Xiong, Enrique Pérez-Payá, and Juan J. Calvete: cDNA Cloning and Functional Expression of Jerdostatin, a Novel RTS-disintegrin from Trimeresurus jerdonii and a Specific Antagonist of the ${alpha}$ ₁ ${beta}$ ₁ Integrin
J. Biol. Chem. 2005 280: 40714-40722. First Published on October 7, 2005; doi:10.1074/jbc.M509738200 [Abstract] [Full Text] [PDF]

Feng Qian, Wen Wei, Gregory Germino, and Andres Oberhauser: The Nanomechanics of Polycystin-1 Extracellular Region
J. Biol. Chem. 2005 280: 40723-40730. First Published on October 11, 2005; doi:10.1074/jbc.M509650200 [Abstract] [Full Text] [PDF]

Dante Neculai, Ana Mirela Neculai, Sophie Verrier, Kenneth Straub, Klaus Klumpp, Edith Pfitzner, and Stefan Becker: Structure of the Unphosphorylated STAT5a Dimer
J. Biol. Chem. 2005 280: 40782-40787. First Published on September 28, 2005; doi:10.1074/jbc.M507682200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data]

Henryk J. Korza and Matthias Bochtler: Pseudomonas aeruginosa LD-Carboxypeptidase, a Serine Peptidase with a Ser-His-Glu Triad and a Nucleophilic Elbow
J. Biol. Chem. 2005 280: 40802-40812. First Published on September 14, 2005; doi:10.1074/jbc.M506328200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Masaru Goto, Hisashi Muramatsu, Hisaaki Mihara, Tatsuo Kurihara, Nobuyoshi Esaki, Rie Omi, Ikuko Miyahara, and Ken Hirotsu: Crystal Structures of ${Delta}$ ¹-Piperideine-2-carboxylate/ ${Delta}$ ¹-Pyrroline-2-carboxylate Reductase Belonging to a New Family of NAD(P)H-dependent Oxidoreductases: CONFORMATIONAL CHANGE, SUBSTRATE RECOGNITION, AND STEREOCHEMISTRY OF THE REACTION
J. Biol. Chem. 2005 280: 40875-40884. First Published on September 28, 2005; doi:10.1074/jbc.M507399200 [Abstract] [Full Text] [PDF]

Moeava Tehei, Dominique Madern, Bruno Franzetti, and Giuseppe Zaccai: Neutron Scattering Reveals the Dynamic Basis of Protein Adaptation to Extreme Temperature
J. Biol. Chem. 2005 280: 40974-40979. First Published on October 3, 2005; doi:10.1074/jbc.M508417200 [Abstract] [Full Text] [PDF]

Jie Tang, Christine Luong Yu, Steven R. Williams, Eric Springman, Douglas Jeffery, Paul A. Sprengeler, Alberto Estevez, Jun Sampang, William Shrader, Jeff Spencer, Wendy Young, Mary McGrath, and Bradley A. Katz: Expression, Crystallization, and Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein
J. Biol. Chem. 2005 280: 41077-41089. First Published on September 30, 2005; doi:10.1074/jbc.M506766200 [Abstract] [Full Text] [PDF]

Michael A. McDonough, Kathryn L. Kavanagh, Danica Butler, Timothy Searls, Udo Oppermann, and Christopher J. Schofield: Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease
J. Biol. Chem. 2005 280: 41101-41110. First Published on September 25, 2005; doi:10.1074/jbc.M507528200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Barbora Piknova, Mark T. Gladwin, Alan N. Schechter, and Neil Hogg: Electron Paramagnetic Resonance Analysis of Nitrosylhemoglobin in Humans during NO Inhalation
J. Biol. Chem. 2005 280: 40583-40588. First Published on September 23, 2005; doi:10.1074/jbc.M506292200 [Abstract] [Full Text] [PDF]

Ming Luo, Sandra M. Jones, Nicolas Flamand, David M. Aronoff, Marc Peters-Golden, and Thomas G. Brock: Phosphorylation by Protein Kinase A Inhibits Nuclear Import of 5-Lipoxygenase
J. Biol. Chem. 2005 280: 40609-40616. First Published on October 17, 2005; doi:10.1074/jbc.M507045200 [Abstract] [Full Text] [PDF]

Dominic Cuerrier, Tudor Moldoveanu, and Peter L. Davies: Determination of Peptide Substrate Specificity for µ-Calpain by a Peptide Library-based Approach: THE IMPORTANCE OF PRIMED SIDE INTERACTIONS
J. Biol. Chem. 2005 280: 40632-40641. First Published on October 10, 2005; doi:10.1074/jbc.M506870200 [Abstract] [Full Text] [PDF]

Hao Zhang, Yingkai Xu, Joy Joseph, and B. Kalyanaraman: Intramolecular Electron Transfer between Tyrosyl Radical and Cysteine Residue Inhibits Tyrosine Nitration and Induces Thiyl Radical Formation in Model Peptides Treated with Myeloperoxidase, H₂O₂, and NO₂^-: EPR SPIN TRAPPING STUDIES
J. Biol. Chem. 2005 280: 40684-40698. First Published on September 21, 2005; doi:10.1074/jbc.M504503200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Byron H. Lee, Srinivasan Yegnasubramanian, Xiaohui Lin, and William G. Nelson: Procainamide Is a Specific Inhibitor of DNA Methyltransferase 1
J. Biol. Chem. 2005 280: 40749-40756. First Published on October 17, 2005; doi:10.1074/jbc.M505593200 [Abstract] [Full Text] [PDF]

Rina Meidan, Eyal Klipper, Tamar Gilboa, Laurent Muller, and Nitzan Levy: Endothelin-converting Enzyme-1, Abundance of Isoforms a-d and Identification of a Novel Alternatively Spliced Variant Lacking a Transmembrane Domain
J. Biol. Chem. 2005 280: 40867-40874. First Published on September 26, 2005; doi:10.1074/jbc.M505679200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Masato Shintaku, Koji Matsuura, Shiro Yoshioka, Satoshi Takahashi, Koichiro Ishimori, and Isao Morishima: Absence of a Detectable Intermediate in the Compound I Formation of Horseradish Peroxidase at Ambient Temperature
J. Biol. Chem. 2005 280: 40934-40938. First Published on October 12, 2005; doi:10.1074/jbc.M503472200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nicole R. Buan and Jorge C. Escalante-Semerena: Computer-assisted Docking of Flavodoxin with the ATP:Co(I)rrinoid Adenosyltransferase (CobA) Enzyme Reveals Residues Critical for Protein-Protein Interactions but Not for Catalysis
J. Biol. Chem. 2005 280: 40948-40956. First Published on October 5, 2005; doi:10.1074/jbc.M506713200 [Abstract] [Full Text] [PDF]

Shizue Katoh, Yuki Tsunoda, Katsuyoshi Murata, Eiichi Minami, and Etsuko Katoh: Active Site Residues and Amino Acid Specificity of the Ubiquitin Carrier Protein-binding RING-H2 Finger Domain
J. Biol. Chem. 2005 280: 41015-41024. First Published on September 26, 2005; doi:10.1074/jbc.M411127200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zhong-Liu Wu, Larissa M. Podust, and F. Peter Guengerich: Expansion of Substrate Specificity of Cytochrome P450 2A6 by Random and Site-directed Mutagenesis
J. Biol. Chem. 2005 280: 41090-41100. First Published on October 7, 2005; doi:10.1074/jbc.M508182200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Cecilia D'Alessio, Julio J. Caramelo, and Armando J. Parodi: Absence of Nucleoside Diphosphatase Activities in the Yeast Secretory Pathway Does Not Abolish Nucleotide Sugar-dependent Protein Glycosylation
J. Biol. Chem. 2005 280: 40417-40427. First Published on September 19, 2005; doi:10.1074/jbc.M503149200 [Abstract] [Full Text] [PDF]

Hildegard Geyer, Manfred Wuhrer, Anja Resemann, and Rudolf Geyer: Identification and Characterization of Keyhole Limpet Hemocyanin N-Glycans Mediating Cross-reactivity with Schistosoma mansoni
J. Biol. Chem. 2005 280: 40731-40748. First Published on August 31, 2005; doi:10.1074/jbc.M505985200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Thomas J. Broekelmann, Beth A. Kozel, Hideaki Ishibashi, Claudio C. Werneck, Fred W. Keeley, Lijuan Zhang, and Robert P. Mecham: Tropoelastin Interacts with Cell-surface Glycosaminoglycans via Its COOH-terminal Domain
J. Biol. Chem. 2005 280: 40939-40947. First Published on September 27, 2005; doi:10.1074/jbc.M507309200 [Abstract] [Full Text] [PDF]

Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Willy Peumans, Els Van Damme, and Dominique Schols: Carbohydrate-binding Agents Cause Deletions of Highly Conserved Glycosylation Sites in HIV GP120: A NEW THERAPEUTIC CONCEPT TO HIT THE ACHILLES HEEL OF HIV
J. Biol. Chem. 2005 280: 41005-41014. First Published on September 23, 2005; doi:10.1074/jbc.M508801200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Susumu Mitsutake and Yasuyuki Igarashi: Calmodulin Is Involved in the Ca²⁺-dependent Activation of Ceramide Kinase as a Calcium Sensor
J. Biol. Chem. 2005 280: 40436-40441. First Published on October 3, 2005; doi:10.1074/jbc.M501962200 [Abstract] [Full Text] [PDF]

Hideru Obinata, Tomoyasu Hattori, Shinji Nakane, Kazuaki Tatei, and Takashi Izumi: Identification of 9-Hydroxyoctadecadienoic Acid and Other Oxidized Free Fatty Acids as Ligands of the G Protein-coupled Receptor G2A
J. Biol. Chem. 2005 280: 40676-40683. First Published on October 19, 2005; doi:10.1074/jbc.M507787200 [Abstract] [Full Text] [PDF]

Gustavo Stadthagen, Jana Korduláková, Ruth Griffin, Patricia Constant, Iveta Bottová, Nathalie Barilone, Brigitte Gicquel, Mamadou Daffé, and Mary Jackson: p-Hydroxybenzoic Acid Synthesis in Mycobacterium tuberculosis
J. Biol. Chem. 2005 280: 40699-40706. First Published on October 6, 2005; doi:10.1074/jbc.M508332200 [Abstract] [Full Text] [PDF]

Hiroyuki Sugimoto, Koichi Okamura, Sayaka Sugimoto, Motoyasu Satou, Tomoyasu Hattori, Dennis E. Vance, and Takashi Izumi: Sp1 Is a Co-activator with Ets-1, and Net Is an Important Repressor of the Transcription of CTP:Phosphocholine Cytidylyltransferase ${alpha}$
J. Biol. Chem. 2005 280: 40857-40866. First Published on September 12, 2005; doi:10.1074/jbc.M503578200 [Abstract] [Full Text] [PDF]

Wei Chen, Nan Li, Taoyong Chen, Yanmei Han, Changfei Li, Yuzhen Wang, Weigang He, Lihuang Zhang, Tao Wan, and Xuetao Cao: The Lysosome-associated Apoptosis-inducing Protein Containing the Pleckstrin Homology (PH) and FYVE Domains (LAPF), Representative of a Novel Family of PH and FYVE Domain-containing Proteins, Induces Caspase-independent Apoptosis via the Lysosomal-Mitochondrial Pathway
J. Biol. Chem. 2005 280: 40985-40995. First Published on September 27, 2005; doi:10.1074/jbc.M502190200 [Abstract] [Full Text] [PDF]

Rita Garuti, Christopher Jones, Wei-Ping Li, Peter Michaely, Joachim Herz, Robert D. Gerard, Jonathan C. Cohen, and Helen H. Hobbs: The Modular Adaptor Protein Autosomal Recessive Hypercholesterolemia (ARH) Promotes Low Density Lipoprotein Receptor Clustering into Clathrin-coated Pits
J. Biol. Chem. 2005 280: 40996-41004. First Published on September 22, 2005; doi:10.1074/jbc.M509394200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Mark A. Cervinski, James D. Foster, and Roxanne A. Vaughan: Psychoactive Substrates Stimulate Dopamine Transporter Phosphorylation and Down-regulation by Cocaine-sensitive and Protein Kinase C-dependent Mechanisms
J. Biol. Chem. 2005 280: 40442-40449. First Published on October 4, 2005; doi:10.1074/jbc.M501969200 [Abstract] [Full Text] [PDF]

Yanru Wang, Takao Inoue, and Michael Forgac: Subunit a of the Yeast V-ATPase Participates in Binding of Bafilomycin
J. Biol. Chem. 2005 280: 40481-40488. First Published on October 10, 2005; doi:10.1074/jbc.M509106200 [Abstract] [Full Text] [PDF]

My N. Helms, Lian Liu, You-You Liang, Otor Al-Khalili, Alain Vandewalle, Sunil Saxena, Douglas C. Eaton, and He-Ping Ma: Phosphatidylinositol 3,4,5-Trisphosphate Mediates Aldosterone Stimulation of Epithelial Sodium Channel (ENaC) and Interacts with ${gamma}$ -ENaC
J. Biol. Chem. 2005 280: 40885-40891. First Published on October 4, 2005; doi:10.1074/jbc.M509646200 [Abstract] [Full Text] [PDF]

Yoshiteru Miyauchi, Toshimi Michigami, Naoko Sakaguchi, Toshihiro Sekimoto, Yoshihiro Yoneda, John Wesley Pike, Masayo Yamagata, and Keiichi Ozono: Importin 4 Is Responsible for Ligand-independent Nuclear Translocation of Vitamin D Receptor
J. Biol. Chem. 2005 280: 40901-40908. First Published on October 5, 2005; doi:10.1074/jbc.M509347200 [Abstract] [Full Text] [PDF]

Lorenzo Guerra, Teresa Fanelli, Maria Favia, Stefania M. Riccardi, Giovanni Busco, Rosa Angela Cardone, Salvatore Carrabino, Edward J. Weinman, Stephan Joel Reshkin, Massimo Conese, and Valeria Casavola: Na⁺/H⁺ Exchanger Regulatory Factor Isoform 1 Overexpression Modulates Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Activity in Human Airway 16HBE14o- Cells and Rescues ${Delta}$ F508 CFTR Functional Expression in Cystic Fibrosis Cells
J. Biol. Chem. 2005 280: 40925-40933. First Published on October 3, 2005; doi:10.1074/jbc.M505103200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shelley M. Elvington, Fang Bu, and J. Wylie Nichols: Fluorescent, Acyl Chain-labeled Phosphatidylcholine Analogs Reveal Novel Transport Pathways across the Plasma Membrane of Yeast
J. Biol. Chem. 2005 280: 40957-40964. First Published on October 4, 2005; doi:10.1074/jbc.M507926200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Richard C. Hresko and Mike Mueckler: mTOR·RICTOR Is the Ser⁴⁷³ Kinase for Akt/Protein Kinase B in 3T3-L1 Adipocytes
J. Biol. Chem. 2005 280: 40406-40416. First Published on October 11, 2005; doi:10.1074/jbc.M508361200 [Abstract] [Full Text] [PDF]

Christos Polytarchou, Maria Hatziapostolou, and Evangelia Papadimitriou: Hydrogen Peroxide Stimulates Proliferation and Migration of Human Prostate Cancer Cells through Activation of Activator Protein-1 and Up-regulation of the Heparin Affin Regulatory Peptide Gene
J. Biol. Chem. 2005 280: 40428-40435. First Published on September 30, 2005; doi:10.1074/jbc.M505120200 [Abstract] [Full Text] [PDF]

Guoliang Qing, Zhaoxia Qu, and Gutian Xiao: Stabilization of Basally Translated NF- ${kappa}$ B-inducing Kinase (NIK) Protein Functions as a Molecular Switch of Processing of NF- ${kappa}$ B2 p100
J. Biol. Chem. 2005 280: 40578-40582. First Published on October 13, 2005; doi:10.1074/jbc.M508776200 [Abstract] [Full Text] [PDF]

Eugene Varfolomeev, Heather Maecker, Darcie Sharp, David Lawrence, Mark Renz, Domagoj Vucic, and Avi Ashkenazi: Molecular Determinants of Kinase Pathway Activation by Apo2 Ligand/Tumor Necrosis Factor-related Apoptosis-inducing Ligand
J. Biol. Chem. 2005 280: 40599-40608. First Published on October 15, 2005; doi:10.1074/jbc.M509560200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Francesco Oriente, Francesco Andreozzi, Chiara Romano, Giuseppe Perruolo, Anna Perfetti, Francesca Fiory, Claudia Miele, Francesco Beguinot, and Pietro Formisano: Protein Kinase C- ${alpha}$ Regulates Insulin Action and Degradation by Interacting with Insulin Receptor Substrate-1 and 14-3-3 ${epsilon}$
J. Biol. Chem. 2005 280: 40642-40649. First Published on October 10, 2005; doi:10.1074/jbc.M508570200 [Abstract] [Full Text] [PDF]

Mariano Janiszewski, Lucia Rossetti Lopes, Alípio O. Carmo, Marcelo A. Pedro, Ralf P. Brandes, Célio X. C. Santos, and Francisco R. M. Laurindo: Regulation of NAD(P)H Oxidase by Associated Protein Disulfide Isomerase in Vascular Smooth Muscle Cells
J. Biol. Chem. 2005 280: 40813-40819. First Published on September 8, 2005; doi:10.1074/jbc.M509255200 [Abstract] [Full Text] [PDF]

Edwina C. Lerner, Ronald P. Trible, Anthony P. Schiavone, James M. Hochrein, John R. Engen, and Thomas E. Smithgall: Activation of the Src Family Kinase Hck without SH3-Linker Release
J. Biol. Chem. 2005 280: 40832-40837. First Published on October 6, 2005; doi:10.1074/jbc.M508782200 [Abstract] [Full Text] [PDF]

Carolina C. P. Mendes, Dawidson A. Gomes, Mayerson Thompson, Natalia C. Souto, Tercio S. Goes, Alfredo M. Goes, Michele A. Rodrigues, Marcus V. Gomez, Michael H. Nathanson, and M. Fatima Leite: The Type III Inositol 1,4,5-Trisphosphate Receptor Preferentially Transmits Apoptotic Ca²⁺ Signals into Mitochondria
J. Biol. Chem. 2005 280: 40892-40900. First Published on September 28, 2005; doi:10.1074/jbc.M506623200 [Abstract] [Full Text] [PDF]

Hiroshi Tanaka, Naoya Fujita, and Takashi Tsuruo: 3-Phosphoinositide-dependent Protein Kinase-1-mediated I ${kappa}$ B Kinase ${beta}$ (IKKB) Phosphorylation Activates NF- ${kappa}$ B Signaling
J. Biol. Chem. 2005 280: 40965-40973. First Published on October 5, 2005; doi:10.1074/jbc.M506235200 [Abstract] [Full Text] [PDF]

Ki M. Kim, Jae J. Song, Jee Young An, Yong Tae Kwon, and Yong J. Lee: Pretreatment of Acetylsalicylic Acid Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis by Down-regulating BCL-2 Gene Expression
J. Biol. Chem. 2005 280: 41047-41056. First Published on September 30, 2005; doi:10.1074/jbc.M503713200 [Abstract] [Full Text] [PDF]

Manuel J. Santos, Rodrigo A. Quintanilla, Andrés Toro, Rodrigo Grandy, Margarita C. Dinamarca, Juan A. Godoy, and Nibaldo C. Inestrosa: Peroxisomal Proliferation Protects from ${beta}$ -Amyloid Neurodegeneration
J. Biol. Chem. 2005 280: 41057-41068. First Published on October 3, 2005; doi:10.1074/jbc.M505160200 [Abstract] [Full Text] [PDF]

Vasily Kerov, Desheng Chen, Mustapha Moussaif, Yu-Jiun Chen, Ching-Kang Chen, and Nikolai O. Artemyev: Transducin Activation State Controls Its Light-dependent Translocation in Rod Photoreceptors
J. Biol. Chem. 2005 280: 41069-41076. First Published on October 4, 2005; doi:10.1074/jbc.M508849200 [Abstract] [Full Text] [PDF]

Hiroki Yoshida, Hirofumi Jono, Hirofumi Kai, and Jian-Dong Li: The Tumor Suppressor Cylindromatosis (CYLD) Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7
J. Biol. Chem. 2005 280: 41111-41121. First Published on October 17, 2005; doi:10.1074/jbc.M509526200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Chaoping Chen, Olivier Vincent, Jing Jin, Ora A. Weisz, and Ronald C. Montelaro: Functions of Early (AP-2) and Late (AIP1/ALIX) Endocytic Proteins in Equine Infectious Anemia Virus Budding
J. Biol. Chem. 2005 280: 40474-40480. First Published on October 7, 2005; doi:10.1074/jbc.M509317200 [Abstract] [Full Text] [PDF]

Meejeon Roh, Chisu Song, Jongchan Kim, and Sarki A. Abdulkadir: Chromosomal Instability Induced by Pim-1 Is Passage-dependent and Associated with Dysregulation of Cyclin B1
J. Biol. Chem. 2005 280: 40568-40577. First Published on October 12, 2005; doi:10.1074/jbc.M509369200 [Abstract] [Full Text] [PDF]

Stephen M. Waters, Robbin M. Brodbeck, Jeremy Steflik, Jianying Yu, Carolyn Baltazar, Amy E. Peck, Daniel Severance, Lu Yan Zhang, Kevin Currie, Bertrand L. Chenard, Alan J. Hutchison, George Maynard, and James E. Krause: Molecular Characterization of the Gerbil C5a Receptor and Identification of a Transmembrane Domain V Amino Acid That Is Crucial for Small Molecule Antagonist Interaction
J. Biol. Chem. 2005 280: 40617-40623. First Published on October 17, 2005; doi:10.1074/jbc.M509245200 [Abstract] [Full Text] [PDF]

Moustapha Alfa Cissé, Claire Sunyach, Solveig Lefranc-Jullien, Rolf Postina, Bruno Vincent, and Frédéric Checler: The Disintegrin ADAM9 Indirectly Contributes to the Physiological Processing of Cellular Prion by Modulating ADAM10 Activity
J. Biol. Chem. 2005 280: 40624-40631. First Published on October 18, 2005; doi:10.1074/jbc.M506069200 [Abstract] [Full Text] [PDF]

Ibragim Gaidarov, Yanqiu Zhao, and James H. Keen: Individual Phosphoinositide 3-Kinase C2 ${alpha}$ Domain Activities Independently Regulate Clathrin Function
J. Biol. Chem. 2005 280: 40766-40772. First Published on October 7, 2005; doi:10.1074/jbc.M507731200 [Abstract] [Full Text] [PDF]

Peter J. Minogue, Xiaoqin Liu, Lisa Ebihara, Eric C. Beyer, and Viviana M. Berthoud: An Aberrant Sequence in a Connexin46 Mutant Underlies Congenital Cataracts
J. Biol. Chem. 2005 280: 40788-40795. First Published on October 3, 2005; doi:10.1074/jbc.M504765200 [Abstract] [Full Text] [PDF]

Viktor I. Korolchuk, Gyles Cozier, and George Banting: Regulation of CK2 Activity by Phosphatidylinositol Phosphates
J. Biol. Chem. 2005 280: 40796-40801. First Published on September 12, 2005; doi:10.1074/jbc.M508988200 [Abstract] [Full Text] [PDF]

Louise Ford, David B. Guiliano, Yelena Oksov, Asim K. Debnath, Jing Liu, Steven A. Williams, Mark L. Blaxter, and Sara Lustigman: Characterization of a Novel Filarial Serine Protease Inhibitor, Ov-SPI-1, from Onchocerca volvulus, with Potential Multifunctional Roles during Development of the Parasite
J. Biol. Chem. 2005 280: 40845-40856. First Published on September 26, 2005; doi:10.1074/jbc.M504434200 [Abstract] [Full Text] [PDF]

Samir S. Taneja, Susan Ha, Nicole K. Swenson, Hong Ying Huang, Peng Lee, Jonathan Melamed, Ellen Shapiro, Michael J. Garabedian, and Susan K. Logan: Cell-specific Regulation of Androgen Receptor Phosphorylation in Vivo
J. Biol. Chem. 2005 280: 40916-40924. First Published on October 6, 2005; doi:10.1074/jbc.M508442200 [Abstract] [Full Text] [PDF]

Sigeng Chen, Ming Ji, Maryline Paris, Ronald L. Hullinger, and Ourania M. Andrisani: The cAMP Pathway Regulates Both Transcription and Activity of the Paired Homeobox Transcription Factor Phox2a Required for Development of Neural Crest-derived and Central Nervous System-derived Catecholaminergic Neurons
J. Biol. Chem. 2005 280: 41025-41036. First Published on October 4, 2005; doi:10.1074/jbc.M503537200 [Abstract] [Full Text] [PDF]

Julie A. Wieland, Andrew A. Gewirth, and Deborah E. Leckband: Single Molecule Adhesion Measurements Reveal Two Homophilic Neural Cell Adhesion Molecule Bonds with Mechanically Distinct Properties
J. Biol. Chem. 2005 280: 41037-41046. First Published on September 27, 2005; doi:10.1074/jbc.M503975200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Yih-Chern Horng, Scot C. Leary, Paul A. Cobine, Fiona B. J. Young, Graham N. George, Eric A. Shoubridge, and Dennis R. Winge: Human Sco1 and Sco2 function as copper-binding proteins. VOLUME 280 (2005) PAGES 34113-34122
J. Biol. Chem. 2005 280: 41122. [Full Text] [PDF]

Neil P. Johnson, Walter A. Baase, and Peter H. von Hippel: Low energy CD of RNA hairpin unveils a loop conformation required for ${lambda}$ N antitermination activity. VOLUME 280 (2005) PAGES 32177-32183
J. Biol. Chem. 2005 280: 41123. [Full Text] [PDF]

Mark Austin and Simon J. Cook: Increased expression of Mcl-1 is required for protection against serum starvation in phosphatase and tensin homologue on chromosome 10 null mouse embryonic fibroblasts, but repression of Bim is favored in human glioblastomas. VOLUME 280 (2005) PAGES 33280-33288
J. Biol. Chem. 2005 280: 41124. [Full Text] [PDF]

Yonghao Yu, Matthew D. Sweeney, Ola M. Saad, Susan E. Crown, Andro R. Hsu, Tracy M. Handel, and Julie A. Leary: Chemokine-glycosaminoglycan binding. SPECIFICITY FOR CCR2 LIGAND BINDING TO HIGHLY SULFATED OLIGOSACCHARIDES USING FTICR MASS SPECTROMETRY. VOLUME 280 (2005) PAGES 32200-32208
J. Biol. Chem. 2005 280: 41124-a. [Full Text] [PDF]

Weijun Jin, Ilia V. Fuki, Nabil G. Seidah, Suzanne Benjannet, Jane M. Glick, and Daniel J. Rader: Proprotein convertases are responsible for proteolysis and inactivation of endothelial lipase. VOLUME 280 (2005) PAGES 36551-36559
J. Biol. Chem. 2005 280: 41124-b. [Full Text] [PDF]