JBC -- Table of Contents (Feb 4 2005, 280, (5))

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Aixin Yan and William J. Lennarz: Unraveling the Mechanism of Protein N-Glycosylation
J. Biol. Chem. 2005 280: 3121-3124. First Published on December 7, 2004; doi:10.1074/jbc.R400036200 [Full Text] [PDF]

Accelerated Publications:

Hyun Ae Woo, Woojin Jeong, Tong-Shin Chang, Kwang Joo Park, Sung Jun Park, Jeong Soo Yang, and Sue Goo Rhee: Reduction of Cysteine Sulfinic Acid by Sulfiredoxin Is Specific to 2-Cys Peroxiredoxins
J. Biol. Chem. 2005 280: 3125-3128. First Published on December 8, 2004; doi:10.1074/jbc.C400496200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Aurelio Reyes, Ming Yao Yang, Mark Bowmaker, and Ian J. Holt: Bidirectional Replication Initiates at Sites Throughout the Mitochondrial Genome of Birds
J. Biol. Chem. 2005 280: 3242-3250. First Published on November 20, 2004; doi:10.1074/jbc.M411916200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Cyril V. Privezentzev, Anthony Keeley, Barbara Sigala, and Irina R. Tsaneva: The Role of RuvA Octamerization for RuvAB Function in Vitro and in Vivo
J. Biol. Chem. 2005 280: 3365-3375. First Published on November 19, 2004; doi:10.1074/jbc.M409256200 [Abstract] [Full Text] [PDF]

Jody L. Plank, Shin Hai Chu, Jennifer Reineke Pohlhaus, Tina Wilson-Sali, and Tao-shih Hsieh: Drosophila melanogaster Topoisomerase III ${alpha}$ Preferentially Relaxes a Positively or Negatively Supercoiled Bubble Substrate and Is Essential during Development
J. Biol. Chem. 2005 280: 3564-3573. First Published on November 10, 2004; doi:10.1074/jbc.M411337200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yuan Liu, William A. Beard, David D. Shock, Rajendra Prasad, Esther W. Hou, and Samuel H. Wilson: DNA Polymerase ${beta}$ and Flap Endonuclease 1 Enzymatic Specificities Sustain DNA Synthesis for Long Patch Base Excision Repair
J. Biol. Chem. 2005 280: 3665-3674. First Published on November 22, 2004; doi:10.1074/jbc.M412922200 [Abstract] [Full Text] [PDF]

Lee H. Wong, Richard Saffery, Melissa A. Anderson, Elizabeth Earle, Julie M. Quach, Angela J. Stafford, Kerry J. Fowler, and K. H. Andy Choo: Analysis of Mitotic and Expression Properties of Human Neocentromere-based Transchromosomes in Mice
J. Biol. Chem. 2005 280: 3954-3962. First Published on November 22, 2004; doi:10.1074/jbc.M410047200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Hung-Yi Wu, Yasuo Hamamori, Jianming Xu, Shin C. Chang, Terry Saluna, Ming-Fu Chang, Bert W. O'Malley, and Larry Kedes: Nuclear Hormone Receptor Coregulator GRIP1 Suppresses, whereas SRC1A and p/CIP Coactivate, by Domain-specific Binding of MyoD
J. Biol. Chem. 2005 280: 3129-3137. First Published on November 24, 2004; doi:10.1074/jbc.M412560200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Christopher A. Wiwi and David J. Waxman: Role of Hepatocyte Nuclear Factors in Transcriptional Regulation of Male-specific CYP2A2
J. Biol. Chem. 2005 280: 3259-3268. First Published on November 10, 2004; doi:10.1074/jbc.M409294200 [Abstract] [Full Text] [PDF]

Shrimati Datta and Timothy F. Osborne: Activation Domains from Both Monomers Contribute to Transcriptional Stimulation by Sterol Regulatory Element-binding Protein Dimers
J. Biol. Chem. 2005 280: 3338-3345. First Published on November 17, 2004; doi:10.1074/jbc.M411222200 [Abstract] [Full Text] [PDF]

John D. Noti, Andrew K. Johnson, and Jill D. Dillon: The Leukocyte Integrin Gene CD11d Is Repressed by Gut-enriched Kruppel-like Factor 4 in Myeloid Cells
J. Biol. Chem. 2005 280: 3449-3457. First Published on November 23, 2004; doi:10.1074/jbc.M412627200 [Abstract] [Full Text] [PDF]

Karen Swales, Satoru Kakizaki, Yukio Yamamoto, Kaoru Inoue, Kaoru Kobayashi, and Masahiko Negishi: Novel CAR-mediated Mechanism for Synergistic Activation of Two Distinct Elements within the Human Cytochrome P450 2B6 Gene in HepG2 Cells
J. Biol. Chem. 2005 280: 3458-3466. First Published on November 24, 2004; doi:10.1074/jbc.M411318200 [Abstract] [Full Text] [PDF]

Qing Guo and Rui Sousa: Multiple Roles for the T7 Promoter Nontemplate Strand during Transcription Initiation and Polymerase Release
J. Biol. Chem. 2005 280: 3474-3482. First Published on November 23, 2004; doi:10.1074/jbc.M412287200 [Abstract] [Full Text] [PDF]

Osamu Matsuda, Hikaru Sakamoto, Tadafumi Hashimoto, and Koh Iba: A Temperature-sensitive Mechanism That Regulates Post-translational Stability of a Plastidial ${omega}$ -3 Fatty Acid Desaturase (FAD8) in Arabidopsis Leaf Tissues
J. Biol. Chem. 2005 280: 3597-3604. First Published on November 15, 2004; doi:10.1074/jbc.M407226200 [Abstract] [Full Text] [PDF] [Suppplemental Data]

Torbjörn Gräslund, Xuelin Li, Laurent Magnenat, Mikhail Popkov, and Carlos F. Barbas, III: Exploring Strategies for the Design of Artificial Transcription Factors: TARGETING SITES PROXIMAL TO KNOWN REGULATORY REGIONS FOR THE INDUCTION OF ${gamma}$ -GLOBIN EXPRESSION AND THE TREATMENT OF SICKLE CELL DISEASE
J. Biol. Chem. 2005 280: 3707-3714. First Published on November 10, 2004; doi:10.1074/jbc.M406809200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Yonglong Zhang, Junjie Zhang, Hiroto Hara, Ikunoshin Kato, and Masayori Inouye: Insights into the mRNA Cleavage Mechanism by MazF, an mRNA Interferase
J. Biol. Chem. 2005 280: 3143-3150. First Published on November 10, 2004; doi:10.1074/jbc.M411811200 [Abstract] [Full Text] [PDF]

Krzysztof Sobczak and Wlodzimierz J. Krzyzosiak: CAG Repeats Containing CAA Interruptions Form Branched Hairpin Structures in Spinocerebellar Ataxia Type 2 Transcripts
J. Biol. Chem. 2005 280: 3898-3910. First Published on November 8, 2004; doi:10.1074/jbc.M409984200 [Abstract] [Full Text] [PDF]

Weidong Yang, Qingde Wang, Kelly L. Howell, Joshua T. Lee, Dan-Sung C. Cho, John M. Murray, and Kazuko Nishikura: ADAR1 RNA Deaminase Limits Short Interfering RNA Efficacy in Mammalian Cells
J. Biol. Chem. 2005 280: 3946-3953. First Published on November 19, 2004; doi:10.1074/jbc.M407876200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Ayako Yamamoto, Arno Friedlein, Yuzuru Imai, Ryosuke Takahashi, Philipp J. Kahle, and Christian Haass: Parkin Phosphorylation and Modulation of Its E3 Ubiquitin Ligase Activity
J. Biol. Chem. 2005 280: 3390-3399. First Published on November 22, 2004; doi:10.1074/jbc.M407724200 [Abstract] [Full Text] [PDF]

Daniel J. Hui, Fulvia Terenzi, William C. Merrick, and Ganes C. Sen: Mouse p56 Blocks a Distinct Function of Eukaryotic Initiation Factor 3 in Translation Initiation
J. Biol. Chem. 2005 280: 3433-3440. First Published on November 23, 2004; doi:10.1074/jbc.M406700200 [Abstract] [Full Text] [PDF]

Dick Terwel, Reena Lasrado, Johan Snauwaert, Erno Vandeweert, Chris Van Haesendonck, Peter Borghgraef, and Fred Van Leuven: Changed Conformation of Mutant Tau-P301L Underlies the Moribund Tauopathy, Absent in Progressive, Nonlethal Axonopathy of Tau-4R/2N Transgenic Mice
J. Biol. Chem. 2005 280: 3963-3973. First Published on October 27, 2004; doi:10.1074/jbc.M409876200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Peter White, John E. Brestelli, Klaus H. Kaestner, and Linda E. Greenbaum: Identification of Transcriptional Networks during Liver Regeneration
J. Biol. Chem. 2005 280: 3715-3722. First Published on November 16, 2004; doi:10.1074/jbc.M410844200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Feng-Qi An, Nicole Compitello, Edward Horwitz, Michael Sramkoski, Erik S. Knudsen, and Rolf Renne: The Latency-associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus Modulates Cellular Gene Expression and Protects Lymphoid Cells from p16 INK4A-induced Cell Cycle Arrest
J. Biol. Chem. 2005 280: 3862-3874. First Published on November 2, 2004; doi:10.1074/jbc.M407435200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Uwe Heinz, Martin Kiefer, Andreas Tholey, and Hans-Werner Adolph: On the Competition for Available Zinc
J. Biol. Chem. 2005 280: 3197-3207. First Published on November 8, 2004; doi:10.1074/jbc.M409425200 [Abstract] [Full Text] [PDF]

Ulla Seppälä, Per Hägglund, Peter A Wurtzen, Henrik Ipsen, Peter Thorsted, Thomas Lenhard, Peter Roepstorff, and Michael D. Spangfort: Molecular Characterization of Major Cat Allergen Fel d 1: EXPRESSION OF HETERODIMER BY USE OF A BACULOVIRUS EXPRESSION SYSTEM
J. Biol. Chem. 2005 280: 3208-3216. First Published on November 15, 2004; doi:10.1074/jbc.M410668200 [Abstract] [Full Text] [PDF]

Sayaka Inagaki, Chiaki Masuda, Tetsuhiro Akaishi, Hiroshi Nakajima, Shiro Yoshioka, Takehiro Ohta, Biswajit Pal, Teizo Kitagawa, and Shigetoshi Aono: Spectroscopic and Redox Properties of a CooA Homologue from Carboxydothermus hydrogenoformans
J. Biol. Chem. 2005 280: 3269-3274. First Published on November 10, 2004; doi:10.1074/jbc.M409884200 [Abstract] [Full Text] [PDF]

Paola Casarosa, Maria Waldhoer, Patricia J. LiWang, Henry F. Vischer, Thomas Kledal, Henk Timmerman, Thue W. Schwartz, Martine J. Smit, and Rob Leurs: CC and CX3C Chemokines Differentially Interact with the N Terminus of the Human Cytomegalovirus-encoded US28 Receptor
J. Biol. Chem. 2005 280: 3275-3285. First Published on November 16, 2004; doi:10.1074/jbc.M407536200 [Abstract] [Full Text] [PDF]

Shao-Wei Li, Jun Zhang, Zhi-Qiang He, Ying Gu, Ru-Shi Liu, Jian Lin, Yi-Xin Chen, Mun-Hon Ng, and Ning-Shao Xia: Mutational Analysis of Essential Interactions Involved in the Assembly of Hepatitis E Virus Capsid
J. Biol. Chem. 2005 280: 3400-3406. First Published on November 22, 2004; doi:10.1074/jbc.M410361200 [Abstract] [Full Text] [PDF]

Joan L. Arolas, Julia Lorenzo, Ana Rovira, Joaquim Castellà, Francesc X. Aviles, and Christian P. Sommerhoff: A Carboxypeptidase Inhibitor from the Tick Rhipicephalus bursa: ISOLATION, cDNA CLONING, RECOMBINANT EXPRESSION, AND CHARACTERIZATION
J. Biol. Chem. 2005 280: 3441-3448. First Published on November 23, 2004; doi:10.1074/jbc.M411086200 [Abstract] [Full Text] [PDF]

Jason Gunawan, Dave Simard, Michel Gilbert, Andrew L. Lovering, Warren W. Wakarchuk, Martin E. Tanner, and Natalie C. J. Strynadka: Structural and Mechanistic Analysis of Sialic Acid Synthase NeuB from Neisseria meningitidis in Complex with Mn²+, Phosphoenolpyruvate, and N-Acetylmannosaminitol
J. Biol. Chem. 2005 280: 3555-3563. First Published on October 29, 2004; doi:10.1074/jbc.M411942200 [Abstract] [Full Text] [PDF]

Chun Ying Song, Wen Liang Chen, Ming Chi Yang, Jen Pin Huang, and Simon J. T. Mao: Epitope Mapping of a Monoclonal Antibody Specific to Bovine Dry Milk: INVOLVEMENT OF RESIDUES 66–76 OF STRAND D IN THERMAL DENATURED ${beta}$ -LACTOGLOBULIN
J. Biol. Chem. 2005 280: 3574-3582. First Published on November 9, 2004; doi:10.1074/jbc.M407031200 [Abstract] [Full Text] [PDF]

Xiang-Qun Xie and Jian-Zhong Chen: NMR Structural Comparison of the Cytoplasmic Juxtamembrane Domains of G-protein-coupled CB₁ and CB₂ Receptors in Membrane Mimetic Dodecylphosphocholine Micelles
J. Biol. Chem. 2005 280: 3605-3612. First Published on November 17, 2004; doi:10.1074/jbc.M410294200 [Abstract] [Full Text] [PDF]

Marcus Pickhardt, Zuzana Gazova, Martin von Bergen, Inna Khlistunova, Yipeng Wang, Antje Hascher, Eva-Maria Mandelkow, Jacek Biernat, and Eckhard Mandelkow: Anthraquinones Inhibit Tau Aggregation and Dissolve Alzheimer's Paired Helical Filaments in Vitro and in Cells
J. Biol. Chem. 2005 280: 3628-3635. First Published on November 2, 2004; doi:10.1074/jbc.M410984200 [Abstract] [Full Text] [PDF]

Douglas V. Laurents, Paul M. Gorman, Meng Guo, Manuel Rico, Avijit Chakrabartty, and Marta Bruix: Alzheimer's A ${beta}$ 40 Studied by NMR at Low pH Reveals That Sodium 4,4-Dimethyl-4-silapentane-1-sulfonate (DSS) Binds and Promotes ${beta}$ -Ball Oligomerization
J. Biol. Chem. 2005 280: 3675-3685. First Published on November 19, 2004; doi:10.1074/jbc.M409507200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Edmund W. Czerwinski, Terumi Midoro-Horiuti, Mark A. White, Edward G. Brooks, and Randall M. Goldblum: Crystal Structure of Jun a 1, the Major Cedar Pollen Allergen from Juniperus ashei, Reveals a Parallel ${beta}$ -Helical Core
J. Biol. Chem. 2005 280: 3740-3746. First Published on November 10, 2004; doi:10.1074/jbc.M409655200 [Abstract] [Full Text] [PDF]

Gerald W. Hsu, Xuanwei Huang, Natalia P. Luneva, Nicholas E. Geacintov, and Lorena S. Beese: Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication
J. Biol. Chem. 2005 280: 3764-3770. First Published on November 16, 2004; doi:10.1074/jbc.M411276200 [Abstract] [Full Text] [PDF]

Derek Ogg, Björn Elleby, Carina Norström, Karin Stefansson, Lars Abrahmsén, Udo Oppermann, and Stefan Svensson: The Crystal Structure of Guinea Pig 11 ${beta}$ -Hydroxysteroid Dehydrogenase Type 1 Provides a Model for Enzyme-Lipid Bilayer Interactions
J. Biol. Chem. 2005 280: 3789-3794. First Published on November 12, 2004; doi:10.1074/jbc.M412463200 [Abstract] [Full Text] [PDF]

José Fernando Díaz, Isabel Barasoain, André A. Souto, Francisco Amat-Guerri, and José Manuel Andreu: Macromolecular Accessibility of Fluorescent Taxoids Bound at a Paclitaxel Binding Site in the Microtubule Surface
J. Biol. Chem. 2005 280: 3928-3937. First Published on November 18, 2004; doi:10.1074/jbc.M407816200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Chi-Ching Hwang, Yi-Hsun Chang, Chao-Nan Hsu, Hsien-Hua Hsu, Chen-Wei Li, and Hwa-I Pon: Mechanistic Roles of Ser-114, Tyr-155, and Lys-159 in 3 ${alpha}$ -Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni
J. Biol. Chem. 2005 280: 3522-3528. First Published on November 29, 2004; doi:10.1074/jbc.M411751200 [Abstract] [Full Text] [PDF]

Anna Jansson, Hanna Koskiniemi, Anna Erola, Jessy Wang, Pekka Mäntsälä, Gunter Schneider, and Jarmo Niemi: Aclacinomycin 10-Hydroxylase Is a Novel Substrate-assisted Hydroxylase Requiring S-Adenosyl-L-methionine as Cofactor
J. Biol. Chem. 2005 280: 3636-3644. First Published on November 17, 2004; doi:10.1074/jbc.M412095200 [Abstract] [Full Text] [PDF]

Jin-Hyung Lee, Jeffry R. Cook, Zhi-Hong Yang, Olga Mirochnitchenko, Samuel I. Gunderson, Arthur M. Felix, Nicole Herth, Ralf Hoffmann, and Sidney Pestka: PRMT7, a New Protein Arginine Methyltransferase That Synthesizes Symmetric Dimethylarginine
J. Biol. Chem. 2005 280: 3656-3664. First Published on October 19, 2004; doi:10.1074/jbc.M405295200 [Abstract] [Full Text] [PDF]

Shunji Takahashi, Yuxin Zhao, Paul E. O'Maille, Bryan T. Greenhagen, Joseph P. Noel, Robert M. Coates, and Joe Chappell: Kinetic and Molecular Analysis of 5-Epiaristolochene 1,3-Dihydroxylase, a Cytochrome P450 Enzyme Catalyzing Successive Hydroxylations of Sesquiterpenes
J. Biol. Chem. 2005 280: 3686-3696. First Published on November 2, 2004; doi:10.1074/jbc.M411870200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Susanne Eschenburg, Melanie Priestman, and Ernst Schönbrunn: Evidence That the Fosfomycin Target Cys¹¹⁵ in UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA) Is Essential for Product Release
J. Biol. Chem. 2005 280: 3757-3763. First Published on November 5, 2004; doi:10.1074/jbc.M411325200 [Abstract] [Full Text] [PDF]

Jérôme Deval, Karine Alvarez, Boulbaba Selmi, Marielle Bermond, Joëlle Boretto, Catherine Guerreiro, Laurence Mulard, and Bruno Canard: Mechanistic Insights into the Suppression of Drug Resistance by Human Immunodeficiency Virus Type 1 Reverse Transcriptase Using ${alpha}$ -Boranophosphate Nucleoside Analogs
J. Biol. Chem. 2005 280: 3838-3846. First Published on November 17, 2004; doi:10.1074/jbc.M411559200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Andrea Eschemann, Alexander Galkin, Walter Oettmeier, Ulrich Brandt, and Stefan Kerscher: HDQ (1-Hydroxy-2-dodecyl-4(1H)quinolone), a High Affinity Inhibitor for Mitochondrial Alternative NADH Dehydrogenase: EVIDENCE FOR A PING-PONG MECHANISM
J. Biol. Chem. 2005 280: 3138-3142. First Published on November 8, 2004; doi:10.1074/jbc.M411217200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jeffrey Middaugh, Robert Hamel, Gael Jean-Baptiste, Robin Beriault, Daniel Chenier, and Vasu D. Appanna: Aluminum Triggers Decreased Aconitase Activity via Fe-S Cluster Disruption and the Overexpression of Isocitrate Dehydrogenase and Isocitrate Lyase: A METABOLIC NETWORK MEDIATING CELLULAR SURVIVAL
J. Biol. Chem. 2005 280: 3159-3165. First Published on November 17, 2004; doi:10.1074/jbc.M411979200 [Abstract] [Full Text] [PDF]

Josep M. Lluis, Albert Morales, Carmen Blasco, Anna Colell, Montserrat Mari, Carmen Garcia-Ruiz, and José C. Fernandez-Checa: Critical Role of Mitochondrial Glutathione in the Survival of Hepatocytes during Hypoxia
J. Biol. Chem. 2005 280: 3224-3232. First Published on November 16, 2004; doi:10.1074/jbc.M408244200 [Abstract] [Full Text] [PDF]

Woonyoung Choi, Eugene W. Gerner, Latha Ramdas, Jheri Dupart, Jennifer Carew, Lynsey Proctor, Peng Huang, Wei Zhang, and Stanley R. Hamilton: Combination of 5-Fluorouracil and N¹,N¹¹-Diethylnorspermine Markedly Activates Spermidine/Spermine N¹-Acetyltransferase Expression, Depletes Polyamines, and Synergistically Induces Apoptosis in Colon Carcinoma Cells
J. Biol. Chem. 2005 280: 3295-3304. First Published on November 16, 2004; doi:10.1074/jbc.M409930200 [Abstract] [Full Text] [PDF]

Ryo Suzuki, Kazuyuki Tobe, Masashi Aoyama, Kentaro Sakamoto, Mitsuru Ohsugi, Nozomu Kamei, Shigeyuki Nemoto, Atsushi Inoue, Yusuke Ito, Shoko Uchida, Kazuo Hara, Toshimasa Yamauchi, Naoto Kubota, Yasuo Terauchi, and Takashi Kadowaki: Expression of DGAT2 in White Adipose Tissue Is Regulated by Central Leptin Action
J. Biol. Chem. 2005 280: 3331-3337. First Published on November 18, 2004; doi:10.1074/jbc.M410955200 [Abstract] [Full Text] [PDF]

Odile Bunoust, Anne Devin, Nicole Avéret, Nadine Camougrand, and Michel Rigoulet: Competition of Electrons to Enter the Respiratory Chain: A NEW REGULATORY MECHANISM OF OXIDATIVE METABOLISM IN SACCHAROMYCES CEREVISIAE
J. Biol. Chem. 2005 280: 3407-3413. First Published on November 22, 2004; doi:10.1074/jbc.M407746200 [Abstract] [Full Text] [PDF]

Krzysztof Zablocki, Joanna Szczepanowska, and Jerzy Duszynski: Extracellular pH Modifies Mitochondrial Control of Capacitative Calcium Entry in Jurkat Cells
J. Biol. Chem. 2005 280: 3516-3521. First Published on November 29, 2004; doi:10.1074/jbc.M411507200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

J. Kevin Langford, Yang Yang, Thomas Kieber-Emmons, and Ralph D. Sanderson: Identification of an Invasion Regulatory Domain within the Core Protein of Syndecan-1
J. Biol. Chem. 2005 280: 3467-3473. First Published on November 24, 2004; doi:10.1074/jbc.M412451200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Michael G. Backlund, Jason R. Mann, Vijaykumar R. Holla, F. Gregory Buchanan, Hsin-Hsiung Tai, Erik S. Musiek, Ginger L. Milne, Sharada Katkuri, and Raymond N. DuBois: 15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Colorectal Cancer
J. Biol. Chem. 2005 280: 3217-3223. First Published on November 12, 2004; doi:10.1074/jbc.M411221200 [Abstract] [Full Text] [PDF]

Katerina Prochazkova, Radim Osicka, Irena Linhartova, Petr Halada, Miroslav Sulc, and Peter Sebo: The Neisseria meningitidis Outer Membrane Lipoprotein FrpD Binds the RTX Protein FrpC
J. Biol. Chem. 2005 280: 3251-3258. First Published on November 2, 2004; doi:10.1074/jbc.M411232200 [Abstract] [Full Text] [PDF]

Roberta Leonardi, Shigeru Chohnan, Yong-Mei Zhang, Kristopher G. Virga, Richard E. Lee, Charles O. Rock, and Suzanne Jackowski: A Pantothenate Kinase from Staphylococcus aureus Refractory to Feedback Regulation by Coenzyme A
J. Biol. Chem. 2005 280: 3314-3322. First Published on November 17, 2004; doi:10.1074/jbc.M411608200 [Abstract] [Full Text] [PDF]

Kaori Fukuhara-Takaki, Masakazu Sakai, Yu-ichiro Sakamoto, Motohiro Takeya, and Seikoh Horiuchi: Expression of Class A Scavenger Receptor Is Enhanced by High Glucose in Vitro and under Diabetic Conditions in Vivo: ONE MECHANISM FOR AN INCREASED RATE OF ATHEROSCLEROSIS IN DIABETES
J. Biol. Chem. 2005 280: 3355-3364. First Published on November 19, 2004; doi:10.1074/jbc.M408715200 [Abstract] [Full Text] [PDF]

Kimberly M. Mayer and John Shanklin: A Structural Model of the Plant Acyl-Acyl Carrier Protein Thioesterase FatB Comprises Two Helix/4-Stranded Sheet Domains, the N-terminal Domain Containing Residues That Affect Specificity and the C-terminal Domain Containing Catalytic Residues
J. Biol. Chem. 2005 280: 3621-3627. First Published on November 4, 2004; doi:10.1074/jbc.M411351200 [Abstract] [Full Text] [PDF]

John D. Davies, Keri L. H. Carpenter, Iain R. Challis, Nikki L. Figg, Rosamund McNair, Diane Proudfoot, Peter L. Weissberg, and Catherine M. Shanahan: Adipocytic Differentiation and Liver X Receptor Pathways Regulate the Accumulation of Triacylglycerols in Human Vascular Smooth Muscle Cells
J. Biol. Chem. 2005 280: 3911-3919. First Published on November 16, 2004; doi:10.1074/jbc.M410075200 [Abstract] [Full Text] [PDF]

Woojin Scott Kim, Michael L. Fitzgerald, Kihwa Kang, Kei-ichiro Okuhira, Susan A. Bell, Jennifer J. Manning, Stephanie L. Koehn, Naifang Lu, Kathryn J. Moore, and Mason W. Freeman: Abca7 Null Mice Retain Normal Macrophage Phosphatidylcholine and Cholesterol Efflux Activity despite Alterations in Adipose Mass and Serum Cholesterol Levels
J. Biol. Chem. 2005 280: 3989-3995. First Published on November 17, 2004; doi:10.1074/jbc.M412602200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Jian Fu, Anjaparavanda P. Naren, Xiaopei Gao, Gias U. Ahmmed, and Asrar B. Malik: Protease-activated Receptor-1 Activation of Endothelial Cells Induces Protein Kinase C ${alpha}$ -dependent Phosphorylation of Syntaxin 4 and Munc18c: ROLE IN SIGNALING P-SELECTIN EXPRESSION
J. Biol. Chem. 2005 280: 3178-3184. First Published on December 2, 2004; doi:10.1074/jbc.M410044200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jason A. Hall and Peter C. Maloney: Altered Oxyanion Selectivity in Mutants of UhpT, the P_i -linked Sugar Phosphate Carrier of Escherichia coli
J. Biol. Chem. 2005 280: 3376-3381. First Published on November 19, 2004; doi:10.1074/jbc.M409965200 [Abstract] [Full Text] [PDF]

Natascha Blaudeck, Peter Kreutzenbeck, Matthias Müller, Georg A. Sprenger, and Roland Freudl: Isolation and Characterization of Bifunctional Escherichia coli TatA Mutant Proteins That Allow Efficient Tat-dependent Protein Translocation in the Absence of TatB
J. Biol. Chem. 2005 280: 3426-3432. First Published on November 22, 2004; doi:10.1074/jbc.M411210200 [Abstract] [Full Text] [PDF]

Morikatsu Yoshida, Susumu Minamisawa, Miei Shimura, Shinji Komazaki, Hideaki Kume, Miao Zhang, Kiyoyuki Matsumura, Miyuki Nishi, Minori Saito, Yasutake Saeki, Yoshihiro Ishikawa, Teruyuki Yanagisawa, and Hiroshi Takeshima: Impaired Ca²⁺ Store Functions in Skeletal and Cardiac Muscle Cells from Sarcalumenin-deficient Mice
J. Biol. Chem. 2005 280: 3500-3506. First Published on November 29, 2004; doi:10.1074/jbc.M406618200 [Abstract] [Full Text] [PDF]

Venkataramana Sidhaye, Jason D. Hoffert, and Landon S. King: cAMP Has Distinct Acute and Chronic Effects on Aquaporin-5 in Lung Epithelial Cells
J. Biol. Chem. 2005 280: 3590-3596. First Published on November 9, 2004; doi:10.1074/jbc.M411038200 [Abstract] [Full Text] [PDF]

Jie Cheng, Hua Wang, and William B. Guggino: Regulation of Cystic Fibrosis Transmembrane Regulator Trafficking and Protein Expression by a Rho Family Small GTPase TC10
J. Biol. Chem. 2005 280: 3731-3739. First Published on November 15, 2004; doi:10.1074/jbc.M410026200 [Abstract] [Full Text] [PDF]

Sebastian L. Müller, Michael Portwich, Anke Schmidt, Darkhan I. Utepbergenov, Otmar Huber, Ingolf E. Blasig, and Gerd Krause: The Tight Junction Protein Occludin and the Adherens Junction Protein ${alpha}$ -Catenin Share a Common Interaction Mechanism with ZO-1
J. Biol. Chem. 2005 280: 3747-3756. First Published on November 16, 2004; doi:10.1074/jbc.M411365200 [Abstract] [Full Text] [PDF]

Marie-Ann Ewart, Mairi Clarke, Susan Kane, Luke H. Chamberlain, and Gwyn W. Gould: Evidence for a Role of the Exocyst in Insulin-stimulated Glut4 Trafficking in 3T3-L1 Adipocytes
J. Biol. Chem. 2005 280: 3812-3816. First Published on November 17, 2004; doi:10.1074/jbc.M409928200 [Abstract] [Full Text] [PDF]

Michelle Ferreri-Jacobia, Don-On Daniel Mak, and J. Kevin Foskett: Translational Mobility of the Type 3 Inositol 1,4,5-Trisphosphate Receptor Ca²⁺ Release Channel in Endoplasmic Reticulum Membrane
J. Biol. Chem. 2005 280: 3824-3831. First Published on November 10, 2004; doi:10.1074/jbc.M409462200 [Abstract] [Full Text] [PDF]

Laurent Taupenot, Kimberly L. Harper, and Daniel T. O'Connor: Role of H⁺-ATPase-mediated Acidification in Sorting and Release of the Regulated Secretory Protein Chromogranin A: EVIDENCE FOR A VESICULOGENIC FUNCTION
J. Biol. Chem. 2005 280: 3885-3897. First Published on November 12, 2004; doi:10.1074/jbc.M408197200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Yan Ling, Laura A. Maile, Jane Badley-Clarke, and David R. Clemmons: DOK1 Mediates SHP-2 Binding to the ${alpha}$ V ${beta}$ 3 Integrin and Thereby Regulates Insulin-like Growth Factor I Signaling in Cultured Vascular Smooth Muscle Cells
J. Biol. Chem. 2005 280: 3151-3158. First Published on November 15, 2004; doi:10.1074/jbc.M411035200 [Abstract] [Full Text] [PDF]

Jan van Riggelen, Gilles Buchwalter, Ubaldo Soto, Johanna De-Castro Arce, Harald zur Hausen, Bohdan Wasylyk, and Frank Rösl: Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells
J. Biol. Chem. 2005 280: 3286-3294. First Published on November 16, 2004; doi:10.1074/jbc.M409915200 [Abstract] [Full Text] [PDF]

Robert M. Gage, Elena A. Matveeva, Sidney W. Whiteheart, and Mark von Zastrow: Type I PDZ Ligands Are Sufficient to Promote Rapid Recycling of G Protein-coupled Receptors Independent of Binding to N-Ethylmaleimide-sensitive Factor
J. Biol. Chem. 2005 280: 3305-3313. First Published on November 17, 2004; doi:10.1074/jbc.M406934200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ramneet Kaur, Xia Liu, Ole Gjoerup, Aihua Zhang, Xin Yuan, Steven P. Balk, Michael C. Schneider, and Michael L. Lu: Activation of p21-activated Kinase 6 by MAP Kinase Kinase 6 and p38 MAP Kinase
J. Biol. Chem. 2005 280: 3323-3330. First Published on November 18, 2004; doi:10.1074/jbc.M406701200 [Abstract] [Full Text] [PDF]

Emanuela Roccato, Claudia Miranda, Giovanna Raho, Sonia Pagliardini, Marco A. Pierotti, and Angela Greco: Analysis of SHP-1-mediated Down-regulation of the TRK-T3 Oncoprotein Identifies Trk-fused Gene (TFG) as a Novel SHP-1-interacting Protein
J. Biol. Chem. 2005 280: 3382-3389. First Published on November 22, 2004; doi:10.1074/jbc.M407522200 [Abstract] [Full Text] [PDF]

Mirko H. H. Schmidt, Ivan Dikic, and Oliver Bögler: Src Phosphorylation of Alix/AIP1 Modulates Its Interaction with Binding Partners and Antagonizes Its Activities
J. Biol. Chem. 2005 280: 3414-3425. First Published on November 22, 2004; doi:10.1074/jbc.M409839200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nhan L. Tran, Wendy S. McDonough, Benjamin A. Savitch, Thomas F. Sawyer, Jeffrey A. Winkles, and Michael E. Berens: The Tumor Necrosis Factor-like Weak Inducer of Apoptosis (TWEAK)-Fibroblast Growth Factor-inducible 14 (Fn14) Signaling System Regulates Glioma Cell Survival via NF ${kappa}$ B Pathway Activation and BCL-X_L/BCL-W Expression
J. Biol. Chem. 2005 280: 3483-3492. First Published on December 16, 2004; doi:10.1074/jbc.M409906200 [Abstract] [Full Text] [PDF]

Brantley R. Herrin, Alison L. Groeger, and Louis B. Justement: The Adaptor Protein HSH2 Attenuates Apoptosis in Response to Ligation of the B Cell Antigen Receptor Complex on the B Lymphoma Cell Line, WEHI-231
J. Biol. Chem. 2005 280: 3507-3515. First Published on November 29, 2004; doi:10.1074/jbc.M407690200 [Abstract] [Full Text] [PDF]

Karla A. Temple, Ronald N. Cohen, Sarah R. Wondisford, Christine Yu, Dianne Deplewski, and Fredric E. Wondisford: An Intact DNA-binding Domain Is Not Required for Peroxisome Proliferator-activated Receptor ${gamma}$ (PPAR ${gamma}$ ) Binding and Activation on Some PPAR Response Elements
J. Biol. Chem. 2005 280: 3529-3540. First Published on November 29, 2004; doi:10.1074/jbc.M411422200 [Abstract] [Full Text] [PDF]

Andrew Beardsley, Kai Fang, Heather Mertz, Vince Castranova, Sherri Friend, and Jun Liu: Loss of Caveolin-1 Polarity Impedes Endothelial Cell Polarization and Directional Movement
J. Biol. Chem. 2005 280: 3541-3547. First Published on October 25, 2004; doi:10.1074/jbc.M409040200 [Abstract] [Full Text] [PDF]

Renée E. Haskew-Layton, Alexander A. Mongin, and Harold K. Kimelberg: Hydrogen Peroxide Potentiates Volume-sensitive Excitatory Amino Acid Release via a Mechanism Involving Ca²+/Calmodulin-dependent Protein Kinase II
J. Biol. Chem. 2005 280: 3548-3554. First Published on November 29, 2004; doi:10.1074/jbc.M409803200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Toshifumi Sugatani and Keith A. Hruska: Akt1/Akt2 and Mammalian Target of Rapamycin/Bim Play Critical Roles in Osteoclast Differentiation and Survival, Respectively, Whereas Akt Is Dispensable for Cell Survival in Isolated Osteoclast Precursors
J. Biol. Chem. 2005 280: 3583-3589. First Published on November 15, 2004; doi:10.1074/jbc.M410480200 [Abstract] [Full Text] [PDF]

Jae Hyuk Yoo, Chan Young Park, Jong Cheol Kim, Won Do Heo, Mi Sun Cheong, Hyeong Cheol Park, Min Chul Kim, Byeong Cheol Moon, Man Soo Choi, Yun Hwan Kang, Ju Huck Lee, Ho Soo Kim, Sang Min Lee, Hae Won Yoon, Chae Oh Lim, Dae-Jin Yun, Sang Yeol Lee, Woo Sik Chung, and Moo Je Cho: Direct Interaction of a Divergent CaM Isoform and the Transcription Factor, MYB2, Enhances Salt Tolerance in Arabidopsis
J. Biol. Chem. 2005 280: 3697-3706. First Published on November 29, 2004; doi:10.1074/jbc.M408237200 [Abstract] [Full Text] [PDF]

Young Chan Chae, Sukmook Lee, Hye Young Lee, Kyun Heo, Jung Hwan Kim, Jong Hyun Kim, Pann-Ghill Suh, and Sung Ho Ryu: Inhibition of Muscarinic Receptor-linked Phospholipase D Activation by Association with Tubulin
J. Biol. Chem. 2005 280: 3723-3730. First Published on November 16, 2004; doi:10.1074/jbc.M406987200 [Abstract] [Full Text] [PDF]

Sunil Laxman, Ana Rascón, and Joseph A. Beavo: Trypanosome Cyclic Nucleotide Phosphodiesterase 2B Binds cAMP through Its GAF-A Domain
J. Biol. Chem. 2005 280: 3771-3779. First Published on November 24, 2004; doi:10.1074/jbc.M408111200 [Abstract] [Full Text] [PDF]

Thomas L. Schmitt, Agnes Hotz-Wagenblatt, Helmut Klein, and Wulf Dröge: Interdependent Regulation of Insulin Receptor Kinase Activity by ADP and Hydrogen Peroxide
J. Biol. Chem. 2005 280: 3795-3801. First Published on November 23, 2004; doi:10.1074/jbc.M410352200 [Abstract] [Full Text] [PDF]

Ariel Mizrahi, Shahar Molshanski-Mor, Carolyn Weinbaum, Yi Zheng, Miriam Hirshberg, and Edgar Pick: Activation of the Phagocyte NADPH Oxidase by Rac Guanine Nucleotide Exchange Factors in Conjunction with ATP and Nucleoside Diphosphate Kinase
J. Biol. Chem. 2005 280: 3802-3811. First Published on November 19, 2004; doi:10.1074/jbc.M410257200 [Abstract] [Full Text] [PDF]

Xin-Hua Liu, Alexander Kirschenbaum, Kang Yu, Shen Yao, and Alice C. Levine: Cyclooxygenase-2 Suppresses Hypoxia-induced Apoptosis via a Combination of Direct and Indirect Inhibition of p53 Activity in a Human Prostate Cancer Cell Line
J. Biol. Chem. 2005 280: 3817-3823. First Published on November 18, 2004; doi:10.1074/jbc.M406577200 [Abstract] [Full Text] [PDF]

W. Richard Burack and Andrey S. Shaw: Live Cell Imaging of ERK and MEK: SIMPLE BINDING EQUILIBRIUM EXPLAINS THE REGULATED NUCLEOCYTOPLASMIC DISTRIBUTION OF ERK
J. Biol. Chem. 2005 280: 3832-3837. First Published on November 16, 2004; doi:10.1074/jbc.M410031200 [Abstract] [Full Text] [PDF]

Yong Qian, Ke Jian Liu, Yan Chen, Daniel C. Flynn, Vince Castranova, and Xianglin Shi: Cdc42 Regulates Arsenic-induced NADPH Oxidase Activation and Cell Migration through Actin Filament Reorganization
J. Biol. Chem. 2005 280: 3875-3884. First Published on October 18, 2004; doi:10.1074/jbc.M403788200 [Abstract] [Full Text] [PDF]

Ling Qin, Joseph Tamasi, Liza Raggatt, Xin Li, Jean H. M. Feyen, David C. Lee, Emanuel DiCicco-Bloom, and Nicola C. Partridge: Amphiregulin Is a Novel Growth Factor Involved in Normal Bone Development and in the Cellular Response to Parathyroid Hormone Stimulation
J. Biol. Chem. 2005 280: 3974-3981. First Published on October 27, 2004; doi:10.1074/jbc.M409807200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Basis Of Cell and Developmental Biology:

Yoshiki Mukudai, Satoshi Kubota, Takanori Eguchi, Seiji Kondo, Kyouji Nakao, and Masaharu Takigawa: Regulation of Chicken ccn2 Gene by Interaction between RNA cis-Element and Putative trans-Factor during Differentiation of Chondrocytes
J. Biol. Chem. 2005 280: 3166-3177. First Published on November 18, 2004; doi:10.1074/jbc.M411632200 [Abstract] [Full Text] [PDF]

Rana Varshochi, Faezah Halim, Andrew Sunters, John P. Alao, Patricia A. Madureira, Stephen M. Hart, Simak Ali, David M. Vigushin, R. Charles Coombes, and Eric W.-F. Lam: ICI182,780 Induces p21^Waf1 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor ${alpha}$ from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line
J. Biol. Chem. 2005 280: 3185-3196. First Published on November 19, 2004; doi:10.1074/jbc.M408063200 [Abstract] [Full Text] [PDF]

Derek K. Emerson, Michael L. McCormick, Jennifer A. Schmidt, and C. Michael Knudson: Taurine Monochloramine Activates a Cell Death Pathway Involving Bax and Caspase-9
J. Biol. Chem. 2005 280: 3233-3241. First Published on November 15, 2004; doi:10.1074/jbc.M411672200 [Abstract] [Full Text] [PDF]

Bo He, Li Liu, George A. Cook, Svetozar Grgurevich, Lisa K. Jennings, and Xin A. Zhang: Tetraspanin CD82 Attenuates Cellular Morphogenesis through Down-regulating Integrin ${alpha}$ 6-Mediated Cell Adhesion
J. Biol. Chem. 2005 280: 3346-3354. First Published on November 19, 2004; doi:10.1074/jbc.M406680200 [Abstract] [Full Text] [PDF]

Koen Brusselmans, Françoise Bono, Désiré Collen, Jean-Marc Herbert, Peter Carmeliet, and Mieke Dewerchin: A Novel Role for Vascular Endothelial Growth Factor as an Autocrine Survival Factor for Embryonic Stem Cells during Hypoxia
J. Biol. Chem. 2005 280: 3493-3499. First Published on November 29, 2004; doi:10.1074/jbc.M406613200 [Abstract] [Full Text] [PDF]

Yun Li, Jianhai Xiang, and Cunming Duan: Insulin-like Growth Factor-binding Protein-3 Plays an Important Role in Regulating Pharyngeal Skeleton and Inner Ear Formation and Differentiation
J. Biol. Chem. 2005 280: 3613-3620. First Published on November 17, 2004; doi:10.1074/jbc.M411479200 [Abstract] [Full Text] [PDF]

Eri Mizuhara, Tomoya Nakatani, Yasuko Minaki, Yoshimasa Sakamoto, and Yuichi Ono: Corl1, a Novel Neuronal Lineage-specific Transcriptional Corepressor for the Homeodomain Transcription Factor Lbx1
J. Biol. Chem. 2005 280: 3645-3655. First Published on November 4, 2004; doi:10.1074/jbc.M411652200 [Abstract] [Full Text] [PDF]

Joshua H. Lipschutz, Shixiong Li, Amy Arisco, and Daniel F. Balkovetz: Extracellular Signal-regulated Kinases 1/2 Control Claudin-2 Expression in Madin-Darby Canine Kidney Strain I and II Cells
J. Biol. Chem. 2005 280: 3780-3788. First Published on November 29, 2004; doi:10.1074/jbc.M408122200 [Abstract] [Full Text] [PDF]

Manju B. Joshi, Matthew E. Rogers, Alison M. Shakarian, Mat Yamage, Saeed A. Al-Harthi, Paul A. Bates, and Dennis M. Dwyer: Molecular Characterization, Expression, and in Vivo Analysis of LmexCht1: THE CHITINASE OF THE HUMAN PATHOGEN, LEISHMANIA MEXICANA
J. Biol. Chem. 2005 280: 3847-3861. First Published on November 22, 2004; doi:10.1074/jbc.M412299200 [Abstract] [Full Text] [PDF]

Min Sup Song, Jin Sook Chang, Su Jeong Song, Tae Hong Yang, Ho Lee, and Dae-Sik Lim: The Centrosomal Protein RAS Association Domain Family Protein 1A (RASSF1A)-binding Protein 1 Regulates Mitotic Progression by Recruiting RASSF1A to Spindle Poles
J. Biol. Chem. 2005 280: 3920-3927. First Published on November 16, 2004; doi:10.1074/jbc.M409115200 [Abstract] [Full Text] [PDF]

Chao-Nan Qian, Jared Knol, Peter Igarashi, Fangming Lin, Uko Zylstra, Bin Tean Teh, and Bart O. Williams: Cystic Renal Neoplasia Following Conditional Inactivation of Apc in Mouse Renal Tubular Epithelium
J. Biol. Chem. 2005 280: 3938-3945. First Published on November 18, 2004; doi:10.1074/jbc.M410697200 [Abstract] [Full Text] [PDF]

Kensuke Takada, Mitsuyoshi Takiguchi, Akihiro Konno, and Mutsumi Inaba: Autoimmunity against a Tissue Kallikrein in IQI/Jic Mice: A MODEL FOR SJÖGREN'S SYNDROME
J. Biol. Chem. 2005 280: 3982-3988. First Published on November 15, 2004; doi:10.1074/jbc.M410157200 [Abstract] [Full Text] [PDF]

Leila R. Aminova, Juan C. Chavez, Junghee Lee, Hoon Ryu, Andrew Kung, Joseph C. LaManna, and Rajiv R. Ratan: Prosurvival and Prodeath Effects of Hypoxia-inducible Factor-1 ${alpha}$ Stabilization in a Murine Hippocampal Cell Line
J. Biol. Chem. 2005 280: 3996-4003. First Published on November 22, 2004; doi:10.1074/jbc.M409223200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Andrew Leask, Alan Holmes, Carol M. Black, and David J. Abraham: Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor- ${beta}$ 2 in fibroblasts. Vol. 278 (2003) 13008–13015
J. Biol. Chem. 2005 280: 4004. [Full Text] [PDF]

Dawn L. Brasaemle, Georgia Dolios, Lawrence Shapiro, and Rong Wang: Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. Vol. 279 (2004) 46835–46842
J. Biol. Chem. 2005 280: 4004-a. [Full Text] [PDF]