JBC -- Table of Contents (Dec 30 2005, 280, (52))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: H. Edwin Umbarger's Contributions to the Discovery of Feedback Inhibition
ISOLEUCINE AND VALINE METABOLISM IN ESCHERICHIA COLI. V. $agr$ -KETOISOVALERIC ACID ACCUMULATION (Edward A. Adelberg and H. Edwin Umbarger J. Biol. Chem. 205, 475-482)
J. Biol. Chem. 2005 280: e49. [Full Text]

Accelerated Publications:

Armando Albert, Daniel Muñoz-Espín, Marta Jiménez, Juan Luis Asensio, Juan A. Hermoso, Margarita Salas, and Wilfried J. J. Meijer: Structural Basis for Membrane Anchorage of Viral ${phi}$ 29 DNA during Replication
J. Biol. Chem. 2005 280: 42486-42488. First Published on November 7, 2005; doi:10.1074/jbc.C500429200 [Abstract] [Full Text] [PDF] [Supplemental Data]

DNA: Replication, Repair, and Recombination:

Korden Walter, Gabriele Warnecke, Richard Bowater, Wolfgang Deppert, and Ella Kim: Tumor Suppressor p53 Binds with High Affinity to CTG·CAG Trinucleotide Repeats and Induces Topological Alterations in Mismatched Duplexes
J. Biol. Chem. 2005 280: 42497-42507. First Published on October 17, 2005; doi:10.1074/jbc.M507038200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Seiji Matsumoto, Keiko Ogino, Eishi Noguchi, Paul Russell, and Hisao Masai: Hsk1-Dfp1/Him1, the Cdc7-Dbf4 Kinase in Schizosaccharomyces pombe, Associates with Swi1, a Component of the Replication Fork Protection Complex
J. Biol. Chem. 2005 280: 42536-42542. First Published on October 31, 2005; doi:10.1074/jbc.M510575200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Deepa Subramanian and Jack D. Griffith: p53 Monitors Replication Fork Regression by Binding to "Chickenfoot" Intermediates
J. Biol. Chem. 2005 280: 42568-42572. First Published on October 4, 2005; doi:10.1074/jbc.M506348200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Ana R. Colina and Dallan Young: Raf60, a Novel Component of the Rpd3 Histone Deacetylase Complex Required for Rpd3 Activity in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 42552-42556. First Published on November 7, 2005; doi:10.1074/jbc.M511561200 [Abstract] [Full Text] [PDF]

Ester Valls, Sara Sánchez-Molina, and Marian A. Martínez-Balbás: Role of Histone Modifications in Marking and Activating Genes through Mitosis
J. Biol. Chem. 2005 280: 42592-42600. First Published on September 30, 2005; doi:10.1074/jbc.M507407200 [Abstract] [Full Text] [PDF]

José I. Piruat and José López-Barneo: Oxygen Tension Regulates Mitochondrial DNA-encoded Complex I Gene Expression
J. Biol. Chem. 2005 280: 42676-42684. First Published on October 28, 2005; doi:10.1074/jbc.M507044200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Karl M. Stuhlmeier and Christine Pollaschek: Adenovirus-mediated Gene Transfer of Mutated I ${kappa}$ B Kinase and I ${kappa}$ B ${alpha}$ Reveal NF- ${kappa}$ B-dependent as Well as NF- ${kappa}$ B-independent Pathways of HAS1 Activation
J. Biol. Chem. 2005 280: 42766-42773. First Published on October 28, 2005; doi:10.1074/jbc.M503374200 [Abstract] [Full Text] [PDF]

Joerg Kumbrink, Marco Gerlinger, and Judith P. Johnson: Egr-1 Induces the Expression of Its Corepressor Nab2 by Activation of the Nab2 Promoter Thereby Establishing a Negative Feedback Loop
J. Biol. Chem. 2005 280: 42785-42793. First Published on October 31, 2005; doi:10.1074/jbc.M511079200 [Abstract] [Full Text] [PDF]

Michela Perani, Per Antonson, Rifat Hamoudi, Catherine J. E. Ingram, Colin S. Cooper, Michelle D. Garrett, and Graham H. Goodwin: The Proto-oncoprotein SYT Interacts with SYT-interacting Protein/Co-activator Activator (SIP/CoAA), a Human Nuclear Receptor Co-activator with Similarity to EWS and TLS/FUS Family of Proteins
J. Biol. Chem. 2005 280: 42863-42876. First Published on October 14, 2005; doi:10.1074/jbc.M502963200 [Abstract] [Full Text] [PDF]

Pierre-Antoine Defossez, Kevin F. Kelly, Guillaume J. P. Filion, Roberto Pérez-Torrado, Frédérique Magdinier, Hervé Menoni, Curtis L. Nordgaard, Juliet M. Daniel, and Eric Gilson: The Human Enhancer Blocker CTC-binding Factor Interacts with the Transcription Factor Kaiso
J. Biol. Chem. 2005 280: 43017-43023. First Published on October 17, 2005; doi:10.1074/jbc.M510802200 [Abstract] [Full Text] [PDF]

Wenbo Zhou and Curt R. Freed: DJ-1 Up-regulates Glutathione Synthesis during Oxidative Stress and Inhibits A53T ${alpha}$ -Synuclein Toxicity
J. Biol. Chem. 2005 280: 43150-43158. First Published on October 14, 2005; doi:10.1074/jbc.M507124200 [Abstract] [Full Text] [PDF]

Chuan-dong Geng and Wayne V. Vedeckis: c-Myb and Members of the c-Ets Family of Transcription Factors Act as Molecular Switches to Mediate Opposite Steroid Regulation of the Human Glucocorticoid Receptor 1A Promoter
J. Biol. Chem. 2005 280: 43264-43271. First Published on November 1, 2005; doi:10.1074/jbc.M508245200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Suzanne R. Lee and Kathleen Collins: Starvation-induced Cleavage of the tRNA Anticodon Loop in Tetrahymena thermophila
J. Biol. Chem. 2005 280: 42744-42749. First Published on November 3, 2005; doi:10.1074/jbc.M510356200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anil K. Nair and K. M. J. Menon: Regulation of Luteinizing Hormone Receptor Expression: EVIDENCE OF TRANSLATIONAL SUPPRESSION IN VITRO BY A HORMONALLY REGULATED mRNA-BINDING PROTEIN AND ITS ENDOGENOUS ASSOCIATION WITH LUTEINIZING HORMONE RECEPTOR mRNA IN THE OVARY
J. Biol. Chem. 2005 280: 42809-42816. First Published on November 1, 2005; doi:10.1074/jbc.M503154200 [Abstract] [Full Text] [PDF]

Yuki Saito, Takanori Yokota, Tasuku Mitani, Kaoru Ito, Masayuki Anzai, Makoto Miyagishi, Kazunari Taira, and Hidehiro Mizusawa: Transgenic Small Interfering RNA Halts Amyotrophic Lateral Sclerosis in a Mouse Model
J. Biol. Chem. 2005 280: 42826-42830. First Published on October 12, 2005; doi:10.1074/jbc.M507685200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Andrew R. Thompsett, Salama R. Abdelraheim, Maki Daniels, and David R. Brown: High Affinity Binding between Copper and Full-length Prion Protein Identified by Two Different Techniques
J. Biol. Chem. 2005 280: 42750-42758. First Published on October 28, 2005; doi:10.1074/jbc.M506521200 [Abstract] [Full Text] [PDF]

Laetitia Thomassin, Claudio C. Werneck, Thomas J. Broekelmann, Claudine Gleyzal, Ian K. Hornstra, Robert P. Mecham, and Pascal Sommer: The Pro-regions of Lysyl Oxidase and Lysyl Oxidase-like 1 Are Required for Deposition onto Elastic Fibers
J. Biol. Chem. 2005 280: 42848-42855. First Published on October 26, 2005; doi:10.1074/jbc.M506832200 [Abstract] [Full Text] [PDF]

Alexandra Gerega, Beate Rockel, Jürgen Peters, Tomohiro Tamura, Wolfgang Baumeister, and Peter Zwickl: VAT, the Thermoplasma Homolog of Mammalian p97/VCP, Is an N Domain-regulated Protein Unfoldase
J. Biol. Chem. 2005 280: 42856-42862. First Published on October 19, 2005; doi:10.1074/jbc.M510592200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Eyal Avraham, Raymonde Szargel, Allon Eyal, Ruth Rott, and Simone Engelender: Glycogen Synthase Kinase 3 $beta$ Modulates Synphilin-1 Ubiquitylation and Cellular Inclusion Formation by SIAH: IMPLICATIONS FOR PROTEASOMAL FUNCTION AND LEWY BODY FORMATION
J. Biol. Chem. 2005 280: 42877-42886. First Published on September 20, 2005; doi:10.1074/jbc.M505608200 [Abstract] [Full Text] [PDF]

Naoki Nanashima, Jumpei Asano, Makoto Hayakari, Toshiya Nakamura, Hajime Nakano, Toshiyuki Yamada, Takeshi Shimizu, Miki Akita, Yang Fan, and Shigeki Tsuchida: Nuclear Localization of STAT5A Modified with O-Linked N-Acetylglucosamine and Early Involution in the Mammary Gland of Hirosaki Hairless Rat
J. Biol. Chem. 2005 280: 43010-43016. First Published on October 14, 2005; doi:10.1074/jbc.M509481200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Michael R. Pears, Jonathan D. Cooper, Hannah M. Mitchison, Russell J. Mortishire-Smith, David A. Pearce, and Julian L. Griffin: High Resolution ¹H NMR-based Metabolomics Indicates a Neurotransmitter Cycling Deficit in Cerebral Tissue from a Mouse Model of Batten Disease
J. Biol. Chem. 2005 280: 42508-42514. First Published on October 20, 2005; doi:10.1074/jbc.M507380200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Aigen Fu, Sungsoon Park, and Steven Rodermel: Sequences Required for the Activity of PTOX (IMMUTANS), a Plastid Terminal Oxidase: IN VITRO AND IN PLANTA MUTAGENESIS OF IRON-BINDING SITES AND A CONSERVED SEQUENCE THAT CORRESPONDS TO EXON 8
J. Biol. Chem. 2005 280: 42489-42496. First Published on October 25, 2005; doi:10.1074/jbc.M508940200 [Abstract] [Full Text] [PDF]

Torgils Fossen, Victor Wray, Karsten Bruns, Judhi Rachmat, Peter Henklein, Uwe Tessmer, Annette Maczurek, Patricia Klinger, and Ulrich Schubert: Solution Structure of the Human Immunodeficiency Virus Type 1 p6 Protein
J. Biol. Chem. 2005 280: 42515-42527. First Published on October 17, 2005; doi:10.1074/jbc.M507375200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Liyan Zhang, Aivar Lookene, Gengshu Wu, and Gunilla Olivecrona: Calcium Triggers Folding of Lipoprotein Lipase into Active Dimers
J. Biol. Chem. 2005 280: 42580-42591. First Published on September 22, 2005; doi:10.1074/jbc.M507252200 [Abstract] [Full Text] [PDF]

Yajnavalka Banerjee, Jun Mizuguchi, Sadaaki Iwanaga, and R. Manjunatha Kini: Hemextin AB Complex, a Unique Anticoagulant Protein Complex from Hemachatus haemachatus (African Ringhals Cobra) Venom That Inhibits Clot Initiation and Factor VIIa Activity
J. Biol. Chem. 2005 280: 42601-42611. First Published on October 4, 2005; doi:10.1074/jbc.M508987200 [Abstract] [Full Text] [PDF]

Atta Ahmad, Vladimir N. Uversky, Dongpyo Hong, and Anthony L. Fink: Early Events in the Fibrillation of Monomeric Insulin
J. Biol. Chem. 2005 280: 42669-42675. First Published on October 24, 2005; doi:10.1074/jbc.M504298200 [Abstract] [Full Text] [PDF]

Enrico Cancellotti, Frances Wiseman, Nadia L. Tuzi, Herbert Baybutt, Paul Monaghan, Lorraine Aitchison, Jennifer Simpson, and Jean C. Manson: Altered Glycosylated PrP Proteins Can Have Different Neuronal Trafficking in Brain but Do Not Acquire Scrapie-like Properties
J. Biol. Chem. 2005 280: 42909-42918. First Published on October 11, 2005; doi:10.1074/jbc.M509557200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zhibin Wu, Xiangqun Li, Erik de Leeuw, Bryan Ericksen, and Wuyuan Lu: Why Is the Arg⁵-Glu¹³ Salt Bridge Conserved in Mammalian ${alpha}$ -Defensins?
J. Biol. Chem. 2005 280: 43039-43047. First Published on October 24, 2005; doi:10.1074/jbc.M510562200 [Abstract] [Full Text] [PDF]

Stéphane Réty, Sylvie Salamitou, Ignacio Garcia-Verdugo, David J. S. Hulmes, Françoise Le Hégarat, Richard Chaby, and Anita Lewit-Bentley: The Crystal Structure of the Bacillus anthracis Spore Surface Protein BclA Shows Remarkable Similarity to Mammalian Proteins
J. Biol. Chem. 2005 280: 43073-43078. First Published on October 25, 2005; doi:10.1074/jbc.M510087200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ryo Iwase, Katsumi Imada, Fumio Hayashi, Tatsuya Uzumaki, Megumi Morishita, Kiyoshi Onai, Yukio Furukawa, Keiichi Namba, and Masahiro Ishiura: Functionally Important Substructures of Circadian Clock Protein KaiB in a Unique Tetramer Complex
J. Biol. Chem. 2005 280: 43141-43149. First Published on October 13, 2005; doi:10.1074/jbc.M503360200 [Abstract] [Full Text] [PDF]

Anita J. Horvath, James A. Irving, Jamie Rossjohn, Ruby H. Law, Stephen P. Bottomley, Noelene S. Quinsey, Robert N. Pike, Paul B. Coughlin, and James C. Whisstock: The Murine Orthologue of Human Antichymotrypsin: A STRUCTURAL PARADIGM FOR CLADE A3 SERPINS
J. Biol. Chem. 2005 280: 43168-43178. First Published on September 4, 2005; doi:10.1074/jbc.M505598200 [Abstract] [Full Text] [PDF]

Tobias S. Ulmer and Ad Bax: Comparison of Structure and Dynamics of Micelle-bound Human ${alpha}$ -Synuclein and Parkinson Disease Variants
J. Biol. Chem. 2005 280: 43179-43187. First Published on September 15, 2005; doi:10.1074/jbc.M507624200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Loretha Carlisle-Moore, Chris R. Gordon, Carl A. Machutta, W. Todd Miller, and Peter J. Tonge: Substrate Recognition by the Human Fatty-acid Synthase
J. Biol. Chem. 2005 280: 42612-42618. First Published on October 7, 2005; doi:10.1074/jbc.M507082200 [Abstract] [Full Text] [PDF]

Thomas Orfeo, Saulius Butenas, Kathleen E. Brummel-Ziedins, and Kenneth G. Mann: The Tissue Factor Requirement in Blood Coagulation
J. Biol. Chem. 2005 280: 42887-42896. First Published on October 7, 2005; doi:10.1074/jbc.M505506200 [Abstract] [Full Text] [PDF]

Erumbi S. Rangarajan, Yunge Li, Eunice Ajamian, Pietro Iannuzzi, Stephanie D. Kernaghan, Marie E. Fraser, Miroslaw Cygler, and Allan Matte: Crystallographic Trapping of the Glutamyl-CoA Thioester Intermediate of Family I CoA Transferases
J. Biol. Chem. 2005 280: 42919-42928. First Published on October 27, 2005; doi:10.1074/jbc.M510522200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Rina Ved, Shamol Saha, Beth Westlund, Celine Perier, Lucinda Burnam, Anne Sluder, Marius Hoener, Cecilia M. P. Rodrigues, Aixa Alfonso, Clifford Steer, Leo Liu, Serge Przedborski, and Benjamin Wolozin: Similar Patterns of Mitochondrial Vulnerability and Rescue Induced by Genetic Modification of ${alpha}$ -Synuclein, Parkin, and DJ-1 in Caenorhabditis elegans
J. Biol. Chem. 2005 280: 42655-42668. First Published on October 19, 2005; doi:10.1074/jbc.M505910200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Sungmun Choi, Eunjung Lee, Soojin Kwon, Haein Park, Jae Youn Yi, Seungin Kim, Inn-Oc Han, Yungdae Yun, and Eok-Soo Oh: Transmembrane Domain-induced Oligomerization Is Crucial for the Functions of Syndecan-2 and Syndecan-4
J. Biol. Chem. 2005 280: 42573-42579. First Published on October 27, 2005; doi:10.1074/jbc.M509238200 [Abstract] [Full Text] [PDF]

Neung-Seon Seo, Anne M. Hocking, Magnus Höök, and David J. McQuillan: Decorin Core Protein Secretion Is Regulated by N-Linked Oligosaccharide and Glycosaminoglycan Additions
J. Biol. Chem. 2005 280: 42774-42784. First Published on October 28, 2005; doi:10.1074/jbc.M511531200 [Abstract] [Full Text] [PDF]

Jinghua Chen, Fikri Y. Avci, Eva M. Muñoz, Lynda M. McDowell, Miao Chen, Lars C. Pedersen, Lijuan Zhang, Robert J. Linhardt, and Jian Liu: Enzymatic Redesigning of Biologically Active Heparan Sulfate
J. Biol. Chem. 2005 280: 42817-42825. First Published on October 31, 2005; doi:10.1074/jbc.M504338200 [Abstract] [Full Text] [PDF]

Hua Zhao, Chengjun Sun, Russell J. Stewart, and J. Herbert Waite: Cement Proteins of the Tube-building Polychaete Phragmatopoma californica
J. Biol. Chem. 2005 280: 42938-42944. First Published on October 14, 2005; doi:10.1074/jbc.M508457200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lipids and Lipoproteins:

Mihee Ko, Kun Zou, Hirohisa Minagawa, Wenxin Yu, Jian-Sheng Gong, Katsuhiko Yanagisawa, and Makoto Michikawa: Cholesterol-mediated Neurite Outgrowth Is Differently Regulated between Cortical and Hippocampal Neurons
J. Biol. Chem. 2005 280: 42759-42765. First Published on November 2, 2005; doi:10.1074/jbc.M509164200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Guoheng Xu, Carole Sztalryd, Xinyue Lu, John T. Tansey, Jaiwei Gan, Heidi Dorward, Alan R. Kimmel, and Constantine Londos: Post-translational Regulation of Adipose Differentiation-related Protein by the Ubiquitin/Proteasome Pathway
J. Biol. Chem. 2005 280: 42841-42847. First Published on August 22, 2005; doi:10.1074/jbc.M506569200 [Abstract] [Full Text] [PDF]

Amiram Ariel, Pin-Lan Li, Wei Wang, Wang-Xian Tang, Gabrielle Fredman, Song Hong, Katherine H. Gotlinger, and Charles N. Serhan: The Docosatriene Protectin D1 Is Produced by T_H2 Skewing and Promotes Human T Cell Apoptosis via Lipid Raft Clustering
J. Biol. Chem. 2005 280: 43079-43086. First Published on October 10, 2005; doi:10.1074/jbc.M509796200 [Abstract] [Full Text] [PDF]

Hsiao-Ping H. Moore, Robert B. Silver, Emilio P. Mottillo, David A. Bernlohr, and James G. Granneman: Perilipin Targets a Novel Pool of Lipid Droplets for Lipolytic Attack by Hormone-sensitive Lipase
J. Biol. Chem. 2005 280: 43109-43120. First Published on October 21, 2005; doi:10.1074/jbc.M506336200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Radosveta Koldamova, Matthias Staufenbiel, and Iliya Lefterov: Lack of ABCA1 Considerably Decreases Brain ApoE Level and Increases Amyloid Deposition in APP23 Mice
J. Biol. Chem. 2005 280: 43224-43235. First Published on October 5, 2005; doi:10.1074/jbc.M504513200 [Abstract] [Full Text] [PDF]

Suzanne E. Wahrle, Hong Jiang, Maia Parsadanian, Richard E. Hartman, Kelly R. Bales, Steven M. Paul, and David M. Holtzman: Deletion of Abca1 Increases A $beta$ Deposition in the PDAPP Transgenic Mouse Model of Alzheimer Disease
J. Biol. Chem. 2005 280: 43236-43242. First Published on October 5, 2005; doi:10.1074/jbc.M508780200 [Abstract] [Full Text] [PDF]

Veronica Hirsch-Reinshagen, Luis F. Maia, Braydon L. Burgess, Jean-Francois Blain, Kathryn E. Naus, Sean A. McIsaac, Pamela F. Parkinson, Jennifer Y. Chan, Gavin H. Tansley, Michael R. Hayden, Judes Poirier, William Van Nostrand, and Cheryl L. Wellington: The Absence of ABCA1 Decreases Soluble ApoE Levels but Does Not Diminish Amyloid Deposition in Two Murine Models of Alzheimer Disease
J. Biol. Chem. 2005 280: 43243-43256. First Published on October 5, 2005; doi:10.1074/jbc.M508781200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Mario H. Barros, Alisha Johnson, Peter Gin, Beth N. Marbois, Catherine F. Clarke, and Alexander Tzagoloff: The Saccharomyces cerevisiae COQ10 Gene Encodes a START Domain Protein Required for Function of Coenzyme Q in Respiration
J. Biol. Chem. 2005 280: 42627-42635. First Published on October 17, 2005; doi:10.1074/jbc.M510768200 [Abstract] [Full Text] [PDF]

Marwan Alfalah, Gabi Wetzel, Ina Fischer, Roger Busche, Erwin E. Sterchi, Klaus-Peter Zimmer, Hans-Peter Sallmann, and Hassan Y. Naim: A Novel Type of Detergent-resistant Membranes May Contribute to an Early Protein Sorting Event in Epithelial Cells
J. Biol. Chem. 2005 280: 42636-42643. First Published on October 17, 2005; doi:10.1074/jbc.M505924200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Silke Richter and Thomas Brüser: Targeting of Unfolded PhoA to the TAT Translocon of Escherichia coli
J. Biol. Chem. 2005 280: 42723-42730. First Published on October 31, 2005; doi:10.1074/jbc.M509570200 [Abstract] [Full Text] [PDF]

Ciming Li, Gilles Crambert, Delphine Thuillard, Sophie Roy, Danièle Schaer, and Käthi Geering: Role of the Transmembrane Domain of FXYD7 in Structural and Functional Interactions with Na,K-ATPase
J. Biol. Chem. 2005 280: 42738-42743. First Published on November 3, 2005; doi:10.1074/jbc.M508451200 [Abstract] [Full Text] [PDF]

Kenji Hoshino, Emi Momiyama, Kaori Yoshida, Kazuhiro Nishimura, Shinobu Sakai, Toshihiko Toida, Keiko Kashiwagi, and Kazuei Igarashi: Polyamine Transport by Mammalian Cells and Mitochondria: ROLE OF ANTIZYME AND GLYCOSAMINOGLYCANS
J. Biol. Chem. 2005 280: 42801-42808. First Published on November 1, 2005; doi:10.1074/jbc.M505445200 [Abstract] [Full Text] [PDF]

Andrei Manolescu, Alexis M. Salas-Burgos, Jorge Fischbarg, and Chris I. Cheeseman: Identification of a Hydrophobic Residue as a Key Determinant of Fructose Transport by the Facilitative Hexose Transporter SLC2A7 (GLUT7)
J. Biol. Chem. 2005 280: 42978-42983. First Published on September 26, 2005; doi:10.1074/jbc.M508678200 [Abstract] [Full Text] [PDF]

Efrosyni Papanikou, Spyridoula Karamanou, Catherine Baud, Miriam Frank, Giorgos Sianidis, Dimitra Keramisanou, Charalampos G. Kalodimos, Andreas Kuhn, and Anastassios Economou: Identification of the Preprotein Binding Domain of SecA
J. Biol. Chem. 2005 280: 43209-43217. First Published on October 21, 2005; doi:10.1074/jbc.M509990200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kirill Kiselyov, Jin Chen, Youssef Rbaibi, Daniel Oberdick, Sandra Tjon-Kon-Sang, Nikolay Shcheynikov, Shmuel Muallem, and Abigail Soyombo: TRP-ML1 Is a Lysosomal Monovalent Cation Channel That Undergoes Proteolytic Cleavage
J. Biol. Chem. 2005 280: 43218-43223. First Published on October 27, 2005; doi:10.1074/jbc.M508210200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Sergio Giannattasio, Zhengchang Liu, Janet Thornton, and Ronald A. Butow: Retrograde Response to Mitochondrial Dysfunction Is Separable from TOR1/2 Regulation of Retrograde Gene Expression
J. Biol. Chem. 2005 280: 42528-42535. First Published on October 27, 2005; doi:10.1074/jbc.M509187200 [Abstract] [Full Text] [PDF]

Howard K. Surks, Nadeene Riddick, and Ken-ichi Ohtani: M-RIP Targets Myosin Phosphatase to Stress Fibers to Regulate Myosin Light Chain Phosphorylation in Vascular Smooth Muscle Cells
J. Biol. Chem. 2005 280: 42543-42551. First Published on October 28, 2005; doi:10.1074/jbc.M506863200 [Abstract] [Full Text] [PDF]

Audrey Varin, Anne-Zélie Decrion, Emmanuelle Sabbah, Vincent Quivy, Joséphine Sire, Carine Van Lint, Bernard P. Roques, Bharat B. Aggarwal, and Georges Herbein: Synthetic Vpr Protein Activates Activator Protein-1, c-Jun N-terminal Kinase, and NF- ${kappa}$ B and Stimulates HIV-1 Transcription in Promonocytic Cells and Primary Macrophages
J. Biol. Chem. 2005 280: 42557-42567. First Published on October 21, 2005; doi:10.1074/jbc.M502211200 [Abstract] [Full Text] [PDF]

Aseem Kumar, Anand Kumar, Paul Michael, Danielle Brabant, Amadeo M. Parissenti, Chilakamarti V. Ramana, Xiulong Xu, and Joseph E. Parrillo: Human Serum from Patients with Septic Shock Activates Transcription Factors STAT1, IRF1, and NF- ${kappa}$ B and Induces Apoptosis in Human Cardiac Myocytes
J. Biol. Chem. 2005 280: 42619-42626. First Published on October 13, 2005; doi:10.1074/jbc.M508416200 [Abstract] [Full Text] [PDF]

Deanna G. Adams, R. Lane Coffee, Jr., Hong Zhang, Steven Pelech, Stefan Strack, and Brian E. Wadzinski: Positive Regulation of Raf1-MEK1/2-ERK1/2 Signaling by Protein Serine/Threonine Phosphatase 2A Holoenzymes
J. Biol. Chem. 2005 280: 42644-42654. First Published on October 20, 2005; doi:10.1074/jbc.M502464200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tetsuo Moriguchi, Seiichi Urushiyama, Naoki Hisamoto, Shun-ichiro Iemura, Shinichi Uchida, Tohru Natsume, Kunihiro Matsumoto, and Hiroshi Shibuya: WNK1 Regulates Phosphorylation of Cation-Chloride-coupled Cotransporters via the STE20-related Kinases, SPAK and OSR1
J. Biol. Chem. 2005 280: 42685-42693. First Published on October 31, 2005; doi:10.1074/jbc.M510042200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yiru Xu, Li-Jun Tan, Vladimir Grachtchouk, John J. Voorhees, and Gary J. Fisher: Receptor-type Protein-tyrosine Phosphatase- ${kappa}$ Regulates Epidermal Growth Factor Receptor Function
J. Biol. Chem. 2005 280: 42694-42700. First Published on October 31, 2005; doi:10.1074/jbc.M507722200 [Abstract] [Full Text] [PDF]

Liangping Yuan, Wen-Mei Yu, Min Xu, and Cheng-Kui Qu: SHP-2 Phosphatase Regulates DNA Damage-induced Apoptosis and G₂/M Arrest in Catalytically Dependent and Independent Manners, Respectively
J. Biol. Chem. 2005 280: 42701-42706. First Published on October 31, 2005; doi:10.1074/jbc.M506768200 [Abstract] [Full Text] [PDF]

Ke-Wen Zhao, Dong Li, Qian Zhao, Ying Huang, Robert H. Silverman, Peter J. Sims, and Guo-Qiang Chen: Interferon- ${alpha}$ -induced Expression of Phospholipid Scramblase 1 through STAT1 Requires the Sequential Activation of Protein Kinase C ${delta}$ and JNK
J. Biol. Chem. 2005 280: 42707-42714. First Published on October 28, 2005; doi:10.1074/jbc.M506178200 [Abstract] [Full Text] [PDF]

Shinichi Kosuga, Etsu Tashiro, Toshifumi Kajioka, Mayumi Ueki, Yoshifumi Shimizu, and Masaya Imoto: GSK-3 $beta$ Directly Phosphorylates and Activates MARK2/PAR-1
J. Biol. Chem. 2005 280: 42715-42722. First Published on October 28, 2005; doi:10.1074/jbc.M507941200 [Abstract] [Full Text] [PDF]

Wenhong Cao, Qu Fan Collins, Thomas C. Becker, Jacques Robidoux, Edgar G. Lupo, Jr., Yan Xiong, Kiefer W. Daniel, Lisa Floering, and Sheila Collins: p38 Mitogen-activated Protein Kinase Plays a Stimulatory Role in Hepatic Gluconeogenesis
J. Biol. Chem. 2005 280: 42731-42737. First Published on November 3, 2005; doi:10.1074/jbc.M506223200 [Abstract] [Full Text] [PDF]

Sushil Kumar Pathak, Sanchita Basu, Asima Bhattacharyya, Shresh Pathak, Manikuntala Kundu, and Joyoti Basu: Mycobacterium tuberculosis Lipoarabinomannan-mediated IRAK-M Induction Negatively Regulates Toll-like Receptor-dependent Interleukin-12 p40 Production in Macrophages
J. Biol. Chem. 2005 280: 42794-42800. First Published on November 1, 2005; doi:10.1074/jbc.M506471200 [Abstract] [Full Text] [PDF]

Nikhil A. Gokhale, Alexandra Abraham, Michelle A. Digman, Enrico Gratton, and Wonhwa Cho: Phosphoinositide Specificity of and Mechanism of Lipid Domain Formation by Annexin A2-p11 Heterotetramer
J. Biol. Chem. 2005 280: 42831-42840. First Published on October 17, 2005; doi:10.1074/jbc.M508129200 [Abstract] [Full Text] [PDF]

Hyun-A. Seong, Haiyoung Jung, Hueng-Sik Choi, Kyong-Tai Kim, and Hyunjung Ha: Regulation of Transforming Growth Factor- $beta$ Signaling and PDK1 Kinase Activity by Physical Interaction between PDK1 and Serine-Threonine Kinase Receptor-associated Protein
J. Biol. Chem. 2005 280: 42897-42908. First Published on October 26, 2005; doi:10.1074/jbc.M507539200 [Abstract] [Full Text] [PDF]

Roma Kenjale, Justin Wilson, Sebastian F. Zenk, Saroj Saurya, Wendy L. Picking, William D. Picking, and Ariel Blocker: The Needle Component of the Type III Secreton of Shigella Regulates the Activity of the Secretion Apparatus
J. Biol. Chem. 2005 280: 42929-42937. First Published on October 14, 2005; doi:10.1074/jbc.M508377200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Judith Haendeler, Rüdiger Popp, Christine Goy, Verena Tischler, Andreas M. Zeiher, and Stefanie Dimmeler: Cathepsin D and H₂O₂ Stimulate Degradation of Thioredoxin-1: IMPLICATION FOR ENDOTHELIAL CELL APOPTOSIS
J. Biol. Chem. 2005 280: 42945-42951. First Published on November 1, 2005; doi:10.1074/jbc.M506985200 [Abstract] [Full Text] [PDF]

Jiliang Li, Dawei Liu, Hua Zhu Ke, Randall L. Duncan, and Charles H. Turner: The P2X₇ Nucleotide Receptor Mediates Skeletal Mechanotransduction
J. Biol. Chem. 2005 280: 42952-42959. First Published on November 3, 2005; doi:10.1074/jbc.M506415200 [Abstract] [Full Text] [PDF]

Claudio Hetz, Pierre-Alain Vitte, Agnes Bombrun, Tatiana K. Rostovtseva, Sylvie Montessuit, Agnes Hiver, Matthias K. Schwarz, Dennis J. Church, Stanley J. Korsmeyer, Jean-Claude Martinou, and Bruno Antonsson: Bax Channel Inhibitors Prevent Mitochondrion-mediated Apoptosis and Protect Neurons in a Model of Global Brain Ischemia
J. Biol. Chem. 2005 280: 42960-42970. First Published on October 11, 2005; doi:10.1074/jbc.M505843200 [Abstract] [Full Text] [PDF]

Yan Du, Barbara C. Böck, Karen A. Schachter, Mary Chao, and Kathleen A. Gallo: Cdc42 Induces Activation Loop Phosphorylation and Membrane Targeting of Mixed Lineage Kinase 3
J. Biol. Chem. 2005 280: 42984-42993. First Published on October 27, 2005; doi:10.1074/jbc.M502671200 [Abstract] [Full Text] [PDF]

Nasreen Khalil, Ying Dong Xu, Robert O'Connor, and Vincent Duronio: Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor- $beta$ 1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK
J. Biol. Chem. 2005 280: 43000-43009. First Published on October 24, 2005; doi:10.1074/jbc.M510441200 [Abstract] [Full Text] [PDF]

Kamala K. Maddali, Donna H. Korzick, Darla L. Tharp, and Douglas K. Bowles: PKC ${delta}$ Mediates Testosterone-induced Increases in Coronary Smooth Muscle Ca_v1.2
J. Biol. Chem. 2005 280: 43024-43029. First Published on October 21, 2005; doi:10.1074/jbc.M509147200 [Abstract] [Full Text] [PDF]

Robert V. Stahelin, Jeong H. Hwang, Jin-Hahn Kim, Zee-Yong Park, Korey R. Johnson, Lina M. Obeid, and Wonhwa Cho: The Mechanism of Membrane Targeting of Human Sphingosine Kinase 1
J. Biol. Chem. 2005 280: 43030-43038. First Published on October 21, 2005; doi:10.1074/jbc.M507574200 [Abstract] [Full Text] [PDF]

Leggy A. Arnold, Eva Estébanez-Perpiñá, Marie Togashi, Natalia Jouravel, Anang Shelat, Andrea C. McReynolds, Ellena Mar, Phuong Nguyen, John D. Baxter, Robert J. Fletterick, Paul Webb, and R. Kiplin Guy: Discovery of Small Molecule Inhibitors of the Interaction of the Thyroid Hormone Receptor with Transcriptional Coregulators
J. Biol. Chem. 2005 280: 43048-43055. First Published on October 31, 2005; doi:10.1074/jbc.M506693200 [Abstract] [Full Text] [PDF]

Marzenna Blonska, Prashant B. Shambharkar, Masayuki Kobayashi, Dongyu Zhang, Hiroaki Sakurai, Bing Su, and Xin Lin: TAK1 Is Recruited to the Tumor Necrosis Factor- ${alpha}$ (TNF- ${alpha}$ ) Receptor 1 Complex in a Receptor-interacting Protein (RIP)-dependent Manner and Cooperates with MEKK3 Leading to NF- ${kappa}$ B Activation
J. Biol. Chem. 2005 280: 43056-43063. First Published on October 31, 2005; doi:10.1074/jbc.M507807200 [Abstract] [Full Text] [PDF]

Wei Liu, Shunqing Wang, Shi Wei, Li Sun, and Xu Feng: Receptor Activator of NF- ${kappa}$ B (RANK) Cytoplasmic Motif, ³⁶⁹PFQEP³⁷³, Plays a Predominant Role in Osteoclast Survival in Part by Activating Akt/PKB and Its Downstream Effector AFX/FOXO4
J. Biol. Chem. 2005 280: 43064-43072. First Published on October 31, 2005; doi:10.1074/jbc.M509006200 [Abstract] [Full Text] [PDF]

Inga Lödige, Andreas Marg, Burkhard Wiesner, Barbora Malecová, Thomas Oelgeschläger, and Uwe Vinkemeier: Nuclear Export Determines the Cytokine Sensitivity of STAT Transcription Factors
J. Biol. Chem. 2005 280: 43087-43099. First Published on September 28, 2005; doi:10.1074/jbc.M509180200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nan-Shan Chang, Joan Doherty, Amy Ensign, Lori Schultz, Li-Jin Hsu, and Qunying Hong: WOX1 Is Essential for Tumor Necrosis Factor-, UV Light-, Staurosporine-, and p53-mediated Cell Death, and Its Tyrosine 33-phosphorylated Form Binds and Stabilizes Serine 46-phosphorylated p53
J. Biol. Chem. 2005 280: 43100-43108. First Published on October 11, 2005; doi:10.1074/jbc.M505590200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data]

Jyothish B. Pillai, Ayman Isbatan, Shin-ichiro Imai, and Mahesh P. Gupta: Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD⁺ Depletion and Reduced Sir2 ${alpha}$ Deacetylase Activity
J. Biol. Chem. 2005 280: 43121-43130. First Published on October 5, 2005; doi:10.1074/jbc.M506162200 [Abstract] [Full Text] [PDF]

Hao Zhang, Xiangyang Xie, Xudong Zhu, Jianhua Zhu, Chunfang Hao, Qiujun Lu, Lihua Ding, Yufei Liu, Lei Zhou, Yaling Liu, Cuifen Huang, Chungen Wen, and Qinong Ye: Stimulatory Cross-talk between NFAT3 and Estrogen Receptor in Breast Cancer Cells
J. Biol. Chem. 2005 280: 43188-43197. First Published on October 11, 2005; doi:10.1074/jbc.M506598200 [Abstract] [Full Text] [PDF]

Maud Frieden, Serge Arnaudeau, Cyril Castelbou, and Nicolas Demaurex: Subplasmalemmal Mitochondria Modulate the Activity of Plasma Membrane Ca²⁺-ATPases
J. Biol. Chem. 2005 280: 43198-43208. First Published on October 10, 2005; doi:10.1074/jbc.M510279200 [Abstract] [Full Text] [PDF]

Bruno Canguilhem, Anne Pradines, Caroline Baudouin, Céline Boby, Isabelle Lajoie-Mazenc, Marie Charveron, and Gilles Favre: RhoB Protects Human Keratinocytes from UVB-induced Apoptosis through Epidermal Growth Factor Receptor Signaling
J. Biol. Chem. 2005 280: 43257-43263. First Published on November 8, 2005; doi:10.1074/jbc.M508650200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Robert S. Carter, Kevin N. Pennington, Pia Arrate, Eugene M. Oltz, and Dean W. Ballard: Site-specific Monoubiquitination of I ${kappa}$ B Kinase IKK $beta$ Regulates Its Phosphorylation and Persistent Activation
J. Biol. Chem. 2005 280: 43272-43279. First Published on November 1, 2005; doi:10.1074/jbc.M508656200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Basis Of Cell and Developmental Biology:

Birgit Weinhold, Ralph Seidenfaden, Iris Röckle, Martina Mühlenhoff, Frank Schertzinger, Sidonie Conzelmann, Jamey D. Marth, Rita Gerardy-Schahn, and Herbert Hildebrandt: Genetic Ablation of Polysialic Acid Causes Severe Neurodevelopmental Defects Rescued by Deletion of the Neural Cell Adhesion Molecule
J. Biol. Chem. 2005 280: 42971-42977. First Published on November 2, 2005; doi:10.1074/jbc.M511097200 [Abstract] [Full Text] [PDF]

Wei Zhang, Lynda Fletcher, and Ruth J. Muschel: The Role of Polo-like Kinase 1 in the Inhibition of Centrosome Separation after Ionizing Radiation
J. Biol. Chem. 2005 280: 42994-42999. First Published on September 12, 2005; doi:10.1074/jbc.M505450200 [Abstract] [Full Text] [PDF]

María V. Baez and Graciela L. Boccaccio: Mammalian Smaug Is a Translational Repressor That Forms Cytoplasmic Foci Similar to Stress Granules
J. Biol. Chem. 2005 280: 43131-43140. First Published on October 12, 2005; doi:10.1074/jbc.M508374200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Olga Vagin, Shahlo Turdikulova, and George Sachs: Recombinant Addition of N-Glycosylation Sites to the Basolateral Na,K-ATPase $beta$ ₁ Subunit Results in Its Clustering in Caveolae and Apical Sorting in HGT-1 Cells
J. Biol. Chem. 2005 280: 43159-43167. First Published on October 17, 2005; doi:10.1074/jbc.M508262200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Isabel D. Alves, Zdzislaw Salamon, Eva Varga, Henry I. Yamamura, Gordon Tollin, and Victor J. Hruby: Direct observation of G-protein binding to the human ${delta}$ -opioid receptor using plasmon-waveguide resonance spectroscopy. VOLUME 278 (2003) PAGES 48890-48897
J. Biol. Chem. 2005 280: 43280-a. [Full Text] [PDF]

Withdrawals:

Kui Zhu, Linnea M. Baudhuin, Guiying Hong, Freager S. Williams, Kelly L. Cristina, Janusz H. S. Kabarowski, Owen N. Witte, and Yan Xu: Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4. VOLUME 276 (2001) PAGES 41325-41335
J. Biol. Chem. 2005 280: 43280. [Full Text] [PDF]