JBC -- Table of Contents (Feb 11 2005, 280, (6))

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Claus-Werner Franzke, Peter Bruckner, and Leena Bruckner-Tuderman: Collagenous Transmembrane Proteins: Recent Insights into Biology and Pathology
J. Biol. Chem. 2005 280: 4005-4008. First Published on November 23, 2004; doi:10.1074/jbc.R400034200 [Full Text] [PDF] [Supplemental Data]

Accelerated Publications:

Elizabeth Buck, Henry Bourne, and James A. Wells: Site-specific Disulfide Capture of Agonist and Antagonist Peptides on the C5a Receptor
J. Biol. Chem. 2005 280: 4009-4012. First Published on November 18, 2004; doi:10.1074/jbc.C400500200 [Abstract] [Full Text] [PDF]

Xavier Altafaj, Weijun Cheng, Eric Estève, Julie Urbani, Didier Grunwald, Jean-Marc Sabatier, Roberto Coronado, Michel De Waard, and Michel Ronjat: Maurocalcine and Domain A of the II-III Loop of the Dihydropyridine Receptor Ca_v 1.1 Subunit Share Common Binding Sites on the Skeletal Ryanodine Receptor
J. Biol. Chem. 2005 280: 4013-4016. First Published on December 9, 2004; doi:10.1074/jbc.C400433200 [Abstract] [Full Text] [PDF]

Mark Gerber, Kristen Tenney, Joan W. Conaway, Ronald C. Conaway, Joel C. Eissenberg, and Ali Shilatifard: Regulation of Heat Shock Gene Expression by RNA Polymerase II Elongation Factor, Elongin A
J. Biol. Chem. 2005 280: 4017-4020. First Published on December 16, 2004; doi:10.1074/jbc.C400487200 [Abstract] [Full Text] [PDF]

Stéphane Hausmann and Stewart Shuman: Specificity and Mechanism of RNA Cap Guanine-N2 Methyltransferase (Tgs1)
J. Biol. Chem. 2005 280: 4021-4024. First Published on December 7, 2004; doi:10.1074/jbc.C400554200 [Abstract] [Full Text] [PDF]

Celia Vogel, Anne Kienitz, Rolf Müller, and Holger Bastians: The Mitotic Spindle Checkpoint Is a Critical Determinant for Topoisomerase-based Chemotherapy
J. Biol. Chem. 2005 280: 4025-4028. First Published on December 16, 2004; doi:10.1074/jbc.C400545200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

David J. Mulvihill, Kerrie Nichol Edamura, Katharine A. Hagerman, Christopher E. Pearson, and Yuh-Hwa Wang: Effect of CAT or AGG Interruptions and CpG Methylation on Nucleosome Assembly upon Trinucleotide Repeats on Spinocerebellar Ataxia, Type 1 and Fragile X Syndrome
J. Biol. Chem. 2005 280: 4498-4503. First Published on December 1, 2004; doi:10.1074/jbc.M413239200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ismail Hassan Ismail, Susanne Nyström, Jonas Nygren, and Ola Hammarsten: Activation of Ataxia Telangiectasia Mutated by DNA Strand Break-inducing Agents Correlates Closely with the Number of DNA Double Strand Breaks
J. Biol. Chem. 2005 280: 4649-4655. First Published on November 15, 2004; doi:10.1074/jbc.M411588200 [Abstract] [Full Text] [PDF]

Nancy Beerens, Jan H. J. Hoeijmakers, Roland Kanaar, Wim Vermeulen, and Claire Wyman: The CSB Protein Actively Wraps DNA
J. Biol. Chem. 2005 280: 4722-4729. First Published on November 16, 2004; doi:10.1074/jbc.M409147200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Jeffrey W. Streb and Joseph M. Miano: AKAP12 ${alpha}$ , an Atypical Serum Response Factor-dependent Target Gene
J. Biol. Chem. 2005 280: 4125-4134. First Published on December 7, 2004; doi:10.1074/jbc.M412466200 [Abstract] [Full Text] [PDF]

Sophie Bonnal, Frédéric Pileur, Cécile Orsini, Fabienne Parker, Françoise Pujol, Anne-Catherine Prats, and Stéphan Vagner: Heterogeneous Nuclear Ribonucleoprotein A1 Is a Novel Internal Ribosome Entry Site trans-Acting Factor That Modulates Alternative Initiation of Translation of the Fibroblast Growth Factor 2 mRNA
J. Biol. Chem. 2005 280: 4144-4153. First Published on November 3, 2004; doi:10.1074/jbc.M411492200 [Abstract] [Full Text] [PDF]

Benjamin Peng, David R. Hodge, Suneetha Betsy Thomas, James M. Cherry, David J. Munroe, Celine Pompeia, Weihua Xiao, and William L. Farrar: Epigenetic Silencing of the Human Nucleotide Excision Repair Gene, hHR23B, in Interleukin-6-responsive Multiple Myeloma KAS-6/1 Cells
J. Biol. Chem. 2005 280: 4182-4187. First Published on November 17, 2004; doi:10.1074/jbc.M412566200 [Abstract] [Full Text] [PDF]

Stephanie E. Kong, Michael S. Kobor, Nevan J. Krogan, Baggavalli P. Somesh, T. Max M. Søgaard, Jack F. Greenblatt, and Jesper Q. Svejstrup: Interaction of Fcp1 Phosphatase with Elongating RNA Polymerase II Holoenzyme, Enzymatic Mechanism of Action, and Genetic Interaction with Elongator
J. Biol. Chem. 2005 280: 4299-4306. First Published on November 24, 2004; doi:10.1074/jbc.M411071200 [Abstract] [Full Text] [PDF]

David M. Selva, Kevin N. Hogeveen, and Geoffrey L. Hammond: Repression of the Human Sex Hormone-binding Globulin Gene in Sertoli Cells by Upstream Stimulatory Transcription Factors
J. Biol. Chem. 2005 280: 4462-4468. First Published on December 1, 2004; doi:10.1074/jbc.M409616200 [Abstract] [Full Text] [PDF]

Fumiki Katsuoka, Hozumi Motohashi, James Douglas Engel, and Masayuki Yamamoto: Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element
J. Biol. Chem. 2005 280: 4483-4490. First Published on December 1, 2004; doi:10.1074/jbc.M411451200 [Abstract] [Full Text] [PDF]

Su Wol Chung, Yen-Hsu Chen, and Mark A. Perrella: Role of Ets-2 in the Regulation of Heme Oxygenase-1 by Endotoxin
J. Biol. Chem. 2005 280: 4578-4584. First Published on December 7, 2004; doi:10.1074/jbc.M409125200 [Abstract] [Full Text] [PDF]

Angela Relógio, Claudia Ben-Dov, Michael Baum, Matteo Ruggiu, Christine Gemund, Vladimir Benes, Robert B. Darnell, and Juan Valcárcel: Alternative Splicing Microarrays Reveal Functional Expression of Neuron-specific Regulators in Hodgkin Lymphoma Cells
J. Biol. Chem. 2005 280: 4779-4784. First Published on November 16, 2004; doi:10.1074/jbc.M411976200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Alfonso Lavado, Concepción Olivares, José Carlos García-Borrón, and Lluís Montoliu: Molecular Basis of the extreme dilution mottled Mouse Mutation: A COMBINATION OF CODING AND NONCODING GENOMIC ALTERATIONS^*
J. Biol. Chem. 2005 280: 4817-4824. First Published on November 30, 2004; doi:10.1074/jbc.M410399200 [Abstract] [Full Text] [PDF]

Weihong Pan, Wendy Mathews, J. Michael Donohue, Margaret L. Ramnaraine, Christine Lynch, Daniel J. Selski, Nicole Walsh, A. Ian Cassady, and Denis R. Clohisy: Analysis of Distinct Tartrate-resistant Acid Phosphatase Promoter Regions in Transgenic Mice
J. Biol. Chem. 2005 280: 4888-4893. First Published on December 7, 2004; doi:10.1074/jbc.M409052200 [Abstract] [Full Text] [PDF]

Gabriele Rieder, Arthur J. Tessier, Xiaotan T. Qiao, Blair Madison, Deborah L. Gumucio, and Juanita L. Merchant: Helicobacter-induced Intestinal Metaplasia in the Stomach Correlates with Elk-1 and Serum Response Factor Induction of Villin
J. Biol. Chem. 2005 280: 4906-4912. First Published on December 2, 2004; doi:10.1074/jbc.M413399200 [Abstract] [Full Text] [PDF]

Laure J. M. Jason, Ron M. Finn, George Lindsey, and Juan Ausió: Histone H2A Ubiquitination Does Not Preclude Histone H1 Binding, but It Facilitates Its Association with the Nucleosome
J. Biol. Chem. 2005 280: 4975-4982. First Published on November 16, 2004; doi:10.1074/jbc.M410203200 [Abstract] [Full Text] [PDF]

Chien-Chung Chen, Meng-Yun Chou, Chun-Hao Huang, Arundhati Majumder, and Hai-Young Wu: A Cis-spreading Nucleoprotein Filament Is Responsible for the Gene Silencing Activity Found in the Promoter Relay Mechanism
J. Biol. Chem. 2005 280: 5101-5112. First Published on December 6, 2004; doi:10.1074/jbc.M411840200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Tomoaki Ogino, Masaki Kobayashi, Minako Iwama, and Kiyohisa Mizumoto: Sendai Virus RNA-dependent RNA Polymerase L Protein Catalyzes Cap Methylation of Virus-specific mRNA
J. Biol. Chem. 2005 280: 4429-4435. First Published on November 30, 2004; doi:10.1074/jbc.M411167200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

J. Thomas Hannich, Alaron Lewis, Mary B. Kroetz, Shyr-Jiann Li, Heinrich Heide, Andrew Emili, and Mark Hochstrasser: Defining the SUMO-modified Proteome by Multiple Approaches in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 4102-4110. First Published on December 6, 2004; doi:10.1074/jbc.M413209200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jie Wei Zhang, Gareth Butland, Jack F. Greenblatt, Andrew Emili, and Deborah B. Zamble: A Role for SlyD in the Escherichia coli Hydrogenase Biosynthetic Pathway
J. Biol. Chem. 2005 280: 4360-4366. First Published on November 29, 2004; doi:10.1074/jbc.M411799200 [Abstract] [Full Text] [PDF]

Ruifeng Zhou and Peter M. Snyder: Nedd4-2 Phosphorylation Induces Serum and Glucocorticoid-regulated Kinase (SGK) Ubiquitination and Degradation
J. Biol. Chem. 2005 280: 4518-4523. First Published on December 2, 2004; doi:10.1074/jbc.M411053200 [Abstract] [Full Text] [PDF]

Valérie Le Fourn, Mireille Ferrand, and Jean-Louis Franc: Endoproteolytic Cleavage of Human Thyroperoxidase: ROLE OF THE PROPEPTIDE IN THE PROTEIN FOLDING PROCESS
J. Biol. Chem. 2005 280: 4568-4577. First Published on December 7, 2004; doi:10.1074/jbc.M408042200 [Abstract] [Full Text] [PDF]

Christian B. Gocke, Hongtao Yu, and Jungseog Kang: Systematic Identification and Analysis of Mammalian Small Ubiquitin-like Modifier Substrates
J. Biol. Chem. 2005 280: 5004-5012. First Published on November 23, 2004; doi:10.1074/jbc.M411718200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genomics, Proteomics, and Bioinformatics:

Vera Pingoud, Anna Sudina, Hildegard Geyer, Janusz M. Bujnicki, Rudi Lurz, Gerhild Lüder, Richard Morgan, Elena Kubareva, and Alfred Pingoud: Specificity Changes in the Evolution of Type II Restriction Endonucleases: A BIOCHEMICAL AND BIOINFORMATIC ANALYSIS OF RESTRICTION ENZYMES THAT RECOGNIZE UNRELATED SEQUENCES
J. Biol. Chem. 2005 280: 4289-4298. First Published on November 24, 2004; doi:10.1074/jbc.M409020200 [Abstract] [Full Text] [PDF]

Fa-Yun Che, Quan Yuan, Elena Kalinina, and Lloyd D. Fricker: Peptidomics of Cpe^fat/fat Mouse Hypothalamus: EFFECT OF FOOD DEPRIVATION AND EXERCISE ON PEPTIDE LEVELS
J. Biol. Chem. 2005 280: 4451-4461. First Published on November 30, 2004; doi:10.1074/jbc.M411178200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Philip Graceffa and Andrew Mazurkie: Effect of Caldesmon on the Position and Myosin-induced Movement of Smooth Muscle Tropomyosin Bound to Actin
J. Biol. Chem. 2005 280: 4135-4143. First Published on October 24, 2004; doi:10.1074/jbc.M410375200 [Abstract] [Full Text] [PDF]

Rick Baggio, Gregory J. Carven, Anthony Chiulli, Michelle Palmer, Lawrence J. Stern, and Jaime E. Arenas: Induced Fit of an Epitope Peptide to a Monoclonal Antibody Probed with a Novel Parallel Surface Plasmon Resonance Assay
J. Biol. Chem. 2005 280: 4188-4194. First Published on November 18, 2004; doi:10.1074/jbc.M410687200 [Abstract] [Full Text] [PDF]

Olga Buczek, Doju Yoshikami, Grzegorz Bulaj, Elsie C. Jimenez, and Baldomero M. Olivera: Post-translational Amino Acid Isomerization: A FUNCTIONALLY IMPORTANT D-AMINO ACID IN AN EXCITATORY PEPTIDE
J. Biol. Chem. 2005 280: 4247-4253. First Published on November 23, 2004; doi:10.1074/jbc.M405835200 [Abstract] [Full Text] [PDF]

David J. Hosfield, Yiqin Wu, Robert J. Skene, Mark Hilgers, Andy Jennings, Gyorgy P. Snell, and Kathleen Aertgeerts: Conformational Flexibility in Crystal Structures of Human 11 ${beta}$ -Hydroxysteroid Dehydrogenase Type I Provide Insights into Glucocorticoid Interconversion and Enzyme Regulation
J. Biol. Chem. 2005 280: 4639-4648. First Published on October 28, 2004; doi:10.1074/jbc.M411104200 [Abstract] [Full Text] [PDF]

Beihai Jiang, Wenbin Liu, Hong Qu, Lin Meng, Shumei Song, Tao Ouyang, and Chengchao Shou: A Novel Peptide Isolated from a Phage Display Peptide Library with Trastuzumab Can Mimic Antigen Epitope of HER-2
J. Biol. Chem. 2005 280: 4656-4662. First Published on November 9, 2004; doi:10.1074/jbc.M411047200 [Abstract] [Full Text] [PDF]

Barbara Zambelli, Massimiliano Stola, Francesco Musiani, Kris De Vriendt, Bart Samyn, Bart Devreese, Jozef Van Beeumen, Paola Turano, Alexander Dikiy, Donald A. Bryant, and Stefano Ciurli: UreG, a Chaperone in the Urease Assembly Process, Is an Intrinsically Unstructured GTPase That Specifically Binds Zn²⁺
J. Biol. Chem. 2005 280: 4684-4695. First Published on November 12, 2004; doi:10.1074/jbc.M408483200 [Abstract] [Full Text] [PDF]

Lei Jin, Pramod Pandey, Robert E. Babine, Joan C. Gorga, Katherine J. Seidl, Ellen Gelfand, David T. Weaver, Sherin S. Abdel-Meguid, and James E. Strickler: Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J. Biol. Chem. 2005 280: 4704-4712. First Published on November 15, 2004; doi:10.1074/jbc.M411309200 [Abstract] [Full Text] [PDF] [Suppplemental Data]

Catherine L. Day, Lin Chen, Sarah J. Richardson, Penny J. Harrison, David C. S. Huang, and Mark G. Hinds: Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands
J. Biol. Chem. 2005 280: 4738-4744. First Published on November 18, 2004; doi:10.1074/jbc.M411434200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mei Y. Choi, Anthony W. Partridge, Craig Daniels, Kai Du, Gergely L. Lukacs, and Charles M. Deber: Destabilization of the Transmembrane Domain Induces Misfolding in a Phenotypic Mutant of Cystic Fibrosis Transmembrane Conductance Regulator
J. Biol. Chem. 2005 280: 4968-4974. First Published on November 10, 2004; doi:10.1074/jbc.M410069200 [Abstract] [Full Text] [PDF]

Lior Cohen, Izhar Karbat, Nicolas Gilles, Nitza Ilan, Morris Benveniste, Dalia Gordon, and Michael Gurevitz: Common Features in the Functional Surface of Scorpion ${beta}$ -Toxins and Elements That Confer Specificity for Insect and Mammalian Voltage-gated Sodium Channels
J. Biol. Chem. 2005 280: 5045-5053. First Published on November 29, 2004; doi:10.1074/jbc.M408427200 [Abstract] [Full Text] [PDF]

Noriko Fujiwara, Yasuhide Miyamoto, Kyoko Ogasahara, Motoko Takahashi, Takahisa Ikegami, Rina Takamiya, Keiichiro Suzuki, and Naoyuki Taniguchi: Different Immunoreactivity against Monoclonal Antibodies between Wild-type and Mutant Copper/Zinc Superoxide Dismutase Linked to Amyotrophic Lateral Sclerosis
J. Biol. Chem. 2005 280: 5061-5070. First Published on November 2, 2004; doi:10.1074/jbc.M406106200 [Abstract] [Full Text] [PDF]

Mads Gravers Jeppesen, Tomas Navratil, Linda Lucy Spremulli, and Jens Nyborg: Crystal Structure of the Bovine Mitochondrial Elongation Factor Tu·Ts Complex
J. Biol. Chem. 2005 280: 5071-5081. First Published on November 22, 2004; doi:10.1074/jbc.M411782200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Torsten Heidenreich, Silke Wollers, Ralf R. Mendel, and Florian Bittner: Characterization of the NifS-like Domain of ABA3 from Arabidopsis thaliana Provides Insight into the Mechanism of Molybdenum Cofactor Sulfuration
J. Biol. Chem. 2005 280: 4213-4218. First Published on November 22, 2004; doi:10.1074/jbc.M411195200 [Abstract] [Full Text] [PDF]

Gernot Schmoock, Frank Pfennig, Julien Jewiarz, Wilhelm Schlumbohm, Werner Laubinger, Florian Schauwecker, and Ullrich Keller: Functional Cross-talk between Fatty Acid Synthesis and Nonribosomal Peptide Synthesis in Quinoxaline Antibiotic-producing Streptomycetes
J. Biol. Chem. 2005 280: 4339-4349. First Published on November 29, 2004; doi:10.1074/jbc.M411026200 [Abstract] [Full Text] [PDF]

Franck Rencurel, Alasdair Stenhouse, Simon A. Hawley, Thomas Friedberg, D. Grahame Hardie, Calum Sutherland, and C. Roland Wolf: AMP-activated Protein Kinase Mediates Phenobarbital Induction of CYP2B Gene Expression in Hepatocytes and a Newly Derived Human Hepatoma Cell Line
J. Biol. Chem. 2005 280: 4367-4373. First Published on November 29, 2004; doi:10.1074/jbc.M412711200 [Abstract] [Full Text] [PDF]

HongYan Liu, Guolu Zheng, Michelle Treber, Jia Dai, and Gebre Woldegiorgis: Cysteine-scanning Mutagenesis of Muscle Carnitine Palmitoyltransferase I Reveals a Single Cysteine Residue (Cys-305) Is Important for Catalysis
J. Biol. Chem. 2005 280: 4524-4531. First Published on December 3, 2004; doi:10.1074/jbc.M400893200 [Abstract] [Full Text] [PDF]

Stephen E. J. Rigby, Robert M. G. Hynson, Rona R. Ramsay, Andrew W. Munro, and Nigel S. Scrutton: A Stable Tyrosyl Radical in Monoamine Oxidase A
J. Biol. Chem. 2005 280: 4627-4631. First Published on November 18, 2004; doi:10.1074/jbc.M410596200 [Abstract] [Full Text] [PDF]

Evelyne Raux-Deery, Helen K. Leech, Kerry-Ann Nakrieko, Kirsty J. McLean, Andrew W. Munro, Peter Heathcote, Stephen E. J. Rigby, Alison G. Smith, and Martin J. Warren: Identification and Characterization of the Terminal Enzyme of Siroheme Biosynthesis from Arabidopsis thaliana: A PLASTID-LOCATED SIROHYDROCHLORIN FERROCHELATASE CONTAINING A 2FE-2S CENTER
J. Biol. Chem. 2005 280: 4713-4721. First Published on November 15, 2004; doi:10.1074/jbc.M411360200 [Abstract] [Full Text] [PDF]

Yixin Zhang, Frank Erdmann, Ria Baumgrass, Mike Schutkowski, and Gunter Fischer: Unexpected Side Chain Effects at Residue 8 of Cyclosporin A Derivatives Allow Photoswitching of Immunosuppression
J. Biol. Chem. 2005 280: 4842-4850. First Published on November 30, 2004; doi:10.1074/jbc.M409178200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolism and Bioenergetics:

Rafal R. Starzynski, Pawel Lipinski, Jean-Claude Drapier, Alexandre Diet, Ewa Smuda, Teresa Bartlomiejczyk, Mikolaj A. Gralak, and Marcin Kruszewski: Down-regulation of Iron Regulatory Protein 1 Activities and Expression in Superoxide Dismutase 1 Knock-out Mice Is Not Associated with Alterations in Iron Metabolism
J. Biol. Chem. 2005 280: 4207-4212. First Published on November 22, 2004; doi:10.1074/jbc.M411055200 [Abstract] [Full Text] [PDF]

Iman M. Ahmad, Nukhet Aykin-Burns, Julia E. Sim, Susan A. Walsh, Ryuji Higashikubo, Garry R. Buettner, Sujatha Venkataraman, Michael A. Mackey, Shawn W. Flanagan, Larry W. Oberley, and Douglas R. Spitz: Mitochondrial O^-^.₂ and H₂O₂ Mediate Glucose Deprivation-induced Stress in Human Cancer Cells
J. Biol. Chem. 2005 280: 4254-4263. First Published on November 23, 2004; doi:10.1074/jbc.M411662200 [Abstract] [Full Text] [PDF]

Meike Hoffmeister, Markus Piotrowski, Ulrich Nowitzki, and William Martin: Mitochondrial trans-2-Enoyl-CoA Reductase of Wax Ester Fermentation from Euglena gracilis Defines a New Family of Enzymes Involved in Lipid Synthesis
J. Biol. Chem. 2005 280: 4329-4338. First Published on November 29, 2004; doi:10.1074/jbc.M411010200 [Abstract] [Full Text] [PDF]

Veronica Contreras-Shannon, An-Ping Lin, Mark T. McCammon, and Lee McAlister-Henn: Kinetic Properties and Metabolic Contributions of Yeast Mitochondrial and Cytosolic NADP⁺-specific Isocitrate Dehydrogenases
J. Biol. Chem. 2005 280: 4469-4475. First Published on December 1, 2004; doi:10.1074/jbc.M410140200 [Abstract] [Full Text] [PDF]

Elizabeth A. Jonas, John A. Hickman, J. Marie Hardwick, and Leonard K. Kaczmarek: Exposure to Hypoxia Rapidly Induces Mitochondrial Channel Activity within a Living Synapse
J. Biol. Chem. 2005 280: 4491-4497. First Published on November 23, 2004; doi:10.1074/jbc.M410661200 [Abstract] [Full Text] [PDF]

Shin Kurihara, Shinpei Oda, Kenji Kato, Hyeon Guk Kim, Takashi Koyanagi, Hidehiko Kumagai, and Hideyuki Suzuki: A Novel Putrescine Utilization Pathway Involves ${gamma}$ -Glutamylated Intermediates of Escherichia coli K-12
J. Biol. Chem. 2005 280: 4602-4608. First Published on December 8, 2004; doi:10.1074/jbc.M411114200 [Abstract] [Full Text] [PDF]

Ying Lin, Anders H. Berg, Puneeth Iyengar, Tony K. T. Lam, Adria Giacca, Terry P. Combs, Michael W. Rajala, Xueliang Du, Brent Rollman, Weijie Li, Meredith Hawkins, Nir Barzilai, Christopher J. Rhodes, I. George Fantus, Michael Brownlee, and Philipp E. Scherer: The Hyperglycemia-induced Inflammatory Response in Adipocytes: THE ROLE OF REACTIVE OXYGEN SPECIES
J. Biol. Chem. 2005 280: 4617-4626. First Published on November 9, 2004; doi:10.1074/jbc.M411863200 [Abstract] [Full Text] [PDF]

Margaret T. T. Wong-Riley, Huan Ling Liang, Janis T. Eells, Britton Chance, Michele M. Henry, Ellen Buchmann, Mary Kane, and Harry T. Whelan: Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins: ROLE OF CYTOCHROME c OXIDASE
J. Biol. Chem. 2005 280: 4761-4771. First Published on November 22, 2004; doi:10.1074/jbc.M409650200 [Abstract] [Full Text] [PDF]

Eric S. Goetzman, Al-Walid A. Mohsen, Kavita Prasad, and Jerry Vockley: Convergent Evolution of a 2-Methylbutyryl-CoA Dehydrogenase from Isovaleryl-CoA Dehydrogenase in Solanum tuberosum
J. Biol. Chem. 2005 280: 4873-4879. First Published on December 1, 2004; doi:10.1074/jbc.M412640200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Chilkunda D. Nandini, Nobuyuki Itoh, and Kazuyuki Sugahara: Novel 70-kDa Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains with a Unique Heterogenous Sulfation Pattern from Shark Skin, Which Exhibit Neuritogenic Activity and Binding Activities for Growth Factors and Neurotrophic Factors
J. Biol. Chem. 2005 280: 4058-4069. First Published on November 19, 2004; doi:10.1074/jbc.M412074200 [Abstract] [Full Text] [PDF]

Dipak K. Banerjee, Elena A. Carrasquillo, Patsy Hughey, John S. Schutzbach, Juan A. Martínez, and Krishna Baksi: In Vitro Phosphorylation by cAMP-dependent Protein Kinase Up-regulates Recombinant Saccharomyces cerevisiae Mannosylphosphodolichol Synthase
J. Biol. Chem. 2005 280: 4174-4181. First Published on November 17, 2004; doi:10.1074/jbc.M406962200 [Abstract] [Full Text] [PDF]

Muriel Bardor, Dzung H. Nguyen, Sandra Diaz, and Ajit Varki: Mechanism of Uptake and Incorporation of the Non-human Sialic Acid N-Glycolylneuraminic Acid into Human Cells
J. Biol. Chem. 2005 280: 4228-4237. First Published on November 22, 2004; doi:10.1074/jbc.M412040200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bruce S. Bochner, Richard A. Alvarez, Padmaja Mehta, Nicolai V. Bovin, Ola Blixt, John R. White, and Ronald L. Schnaar: Glycan Array Screening Reveals a Candidate Ligand for Siglec-8
J. Biol. Chem. 2005 280: 4307-4312. First Published on November 24, 2004; doi:10.1074/jbc.M412378200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hiroko Ideo, Akira Seko, and Katsuko Yamashita: Galectin-4 Binds to Sulfated Glycosphingolipids and Carcinoembryonic Antigen in Patches on the Cell Surface of Human Colon Adenocarcinoma Cells
J. Biol. Chem. 2005 280: 4730-4737. First Published on November 16, 2004; doi:10.1074/jbc.M410362200 [Abstract] [Full Text] [PDF]

Stéphane Bernatchez, Christine M. Szymanski, Noboru Ishiyama, Jianjun Li, Harold C. Jarrell, Peter C. Lau, Albert M. Berghuis, N. Martin Young, and Warren W. Wakarchuk: A Single Bifunctional UDP-GlcNAc/Glc 4-Epimerase Supports the Synthesis of Three Cell Surface Glycoconjugates in Campylobacter jejuni
J. Biol. Chem. 2005 280: 4792-4802. First Published on October 27, 2004; doi:10.1074/jbc.M407767200 [Abstract] [Full Text] [PDF]

Hans H. Wandall, Sandrine Pizette, Johannes W. Pedersen, Heather Eichert, Steven B. Levery, Ulla Mandel, Stephen M. Cohen, and Henrik Clausen: Egghead and Brainiac Are Essential for Glycosphingolipid Biosynthesis in Vivo
J. Biol. Chem. 2005 280: 4858-4863. First Published on December 15, 2004; doi:10.1074/jbc.C400571200 [Abstract] [Full Text] [PDF]

Andrew Marson, Matthew J. Rock, Stuart A. Cain, Lyle J. Freeman, Amanda Morgan, Kieran Mellody, C. Adrian Shuttleworth, Clair Baldock, and Cay M. Kielty: Homotypic Fibrillin-1 Interactions in Microfibril Assembly
J. Biol. Chem. 2005 280: 5013-5021. First Published on November 29, 2004; doi:10.1074/jbc.M409029200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Radosveta P. Koldamova, Iliya M. Lefterov, Matthias Staufenbiel, Darren Wolfe, Shaohua Huang, Joseph C. Glorioso, Michael Walter, Michael G. Roth, and John S. Lazo: The Liver X Receptor Ligand T0901317 Decreases Amyloid ${beta}$ Production in Vitro and in a Mouse Model of Alzheimer's Disease
J. Biol. Chem. 2005 280: 4079-4088. First Published on November 22, 2004; doi:10.1074/jbc.M411420200 [Abstract] [Full Text] [PDF]

Atsushi Ohnishi, Hiroyuki Koshino, Shunya Takahashi, Yasuaki Esumi, and Shogo Matsumoto: Isolation and Characterization of a Humoral Factor That Stimulates Transcription of the Acyl-CoA-binding Protein in the Pheromone Gland of the Silkmoth, Bombyx mori
J. Biol. Chem. 2005 280: 4111-4116. First Published on December 6, 2004; doi:10.1074/jbc.M413429200 [Abstract] [Full Text] [PDF]

Libo Wang, David Atkinson, and Donald M. Small: The Interfacial Properties of ApoA-I and an Amphipathic ${alpha}$ -Helix Consensus Peptide of Exchangeable Apolipoproteins at the Triolein/Water Interface
J. Biol. Chem. 2005 280: 4154-4165. First Published ; doi:10.1074/bc.M411618200 [Abstract] [Full Text] [PDF]

Melody Germann, Evelyn Swain, Lawrence Bergman, and Joseph T. Nickels, Jr.: Characterizing the Sphingolipid Signaling Pathway That Remediates Defects Associated with Loss of the Yeast Amphiphysin-like Orthologs, Rvs161p and Rvs167p
J. Biol. Chem. 2005 280: 4270-4278. First Published on November 23, 2004; doi:10.1074/jbc.M412454200 [Abstract] [Full Text] [PDF]

David W. Zaas, Mathew J. Duncan, Guojie Li, Jo Rae Wright, and Soman N. Abraham: Pseudomonas Invasion of Type I Pneumocytes Is Dependent on the Expression and Phosphorylation of Caveolin-2
J. Biol. Chem. 2005 280: 4864-4872. First Published on November 15, 2004; doi:10.1074/jbc.M411702200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Jing Yang and Geoffrey D. Holman: Insulin and Contraction Stimulate Exocytosis, but Increased AMP-activated Protein Kinase Activity Resulting from Oxidative Metabolism Stress Slows Endocytosis of GLUT4 in Cardiomyocytes
J. Biol. Chem. 2005 280: 4070-4078. First Published on November 22, 2004; doi:10.1074/jbc.M410213200 [Abstract] [Full Text] [PDF]

Oliver Lenz, Matthias T. Dittmar, Andreas Wagner, Boris Ferko, Karola Vorauer-Uhl, Gabriela Stiegler, and Winfried Weissenhorn: Trimeric Membrane-anchored gp41 Inhibits HIV Membrane Fusion
J. Biol. Chem. 2005 280: 4095-4101. First Published on December 1, 2004; doi:10.1074/jbc.M411088200 [Abstract] [Full Text] [PDF]

Cornelia M. Wilson, Claudine Kraft, Claire Duggan, Nurzian Ismail, Samuel G. Crawshaw, and Stephen High: Ribophorin I Associates with a Subset of Membrane Proteins after Their Integration at the Sec61 Translocon
J. Biol. Chem. 2005 280: 4195-4206. First Published on November 19, 2004; doi:10.1074/jbc.M410329200 [Abstract] [Full Text] [PDF]

Csilla Özvegy-Laczka, György Várady, Gabriella Köblös, Olga Ujhelly, Judit Cervenak, John D. Schuetz, Brian P. Sorrentino, Gerrit-Jan Koomen, András Váradi, Katalin Német, and Balázs Sarkadi: Function-dependent Conformational Changes of the ABCG2 Multidrug Transporter Modify Its Interaction with a Monoclonal Antibody on the Cell Surface
J. Biol. Chem. 2005 280: 4219-4227. First Published on November 22, 2004; doi:10.1074/jbc.M411338200 [Abstract] [Full Text] [PDF]

Marcelo D. Carattino, Shaohu Sheng, and Thomas R. Kleyman: Mutations in the Pore Region Modify Epithelial Sodium Channel Gating by Shear Stress
J. Biol. Chem. 2005 280: 4393-4401. First Published on November 29, 2004; doi:10.1074/jbc.M413123200 [Abstract] [Full Text] [PDF]

Jean Chemin, Amanda Patel, Fabrice Duprat, Marc Zanzouri, Michel Lazdunski, and Eric Honoré: Lysophosphatidic Acid-operated K⁺ Channels
J. Biol. Chem. 2005 280: 4415-4421. First Published on November 30, 2004; doi:10.1074/jbc.M408246200 [Abstract] [Full Text] [PDF]

Mohamed E. Abazeed, Jennifer M. Blanchette, and Robert S. Fuller: Cell-free Transport from the trans-Golgi Network to Late Endosome Requires Factors Involved in Formation and Consumption of Clathrin-coated Vesicles
J. Biol. Chem. 2005 280: 4442-4450. First Published on November 30, 2004; doi:10.1074/jbc.M412553200 [Abstract] [Full Text] [PDF]

Boris Tefsen, Jeroen Geurtsen, Frank Beckers, Jan Tommassen, and Hans de Cock: Lipopolysaccharide Transport to the Bacterial Outer Membrane in Spheroplasts
J. Biol. Chem. 2005 280: 4504-4509. First Published on December 2, 2004; doi:10.1074/jbc.M409259200 [Abstract] [Full Text] [PDF]

Meng-Shiunn Lee, Ling-Yun Chen, Wei-Ming Leu, Rong-Jen Shiau, and Nien-Tai Hu: Associations of the Major Pseudopilin XpsG with XpsN (GspC) and Secretin XpsD of Xanthomonas campestris pv. campestris Type II Secretion Apparatus Revealed by Cross-linking Analysis
J. Biol. Chem. 2005 280: 4585-4591. First Published on December 7, 2004; doi:10.1074/jbc.M409362200 [Abstract] [Full Text] [PDF]

Masamitsu Shimazu, Takayuki Sekito, Koichi Akiyama, Yoshinori Ohsumi, and Yoshimi Kakinuma: A Family of Basic Amino Acid Transporters of the Vacuolar Membrane from Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 4851-4857. First Published on November 30, 2004; doi:10.1074/jbc.M412617200 [Abstract] [Full Text] [PDF]

Yanzhuang Wang, Ayano Satoh, and Graham Warren: Mapping the Functional Domains of the Golgi Stacking Factor GRASP65
J. Biol. Chem. 2005 280: 4921-4928. First Published on December 2, 2004; doi:10.1074/jbc.M412407200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ricardo Madrid, Katy Janvier, Douglas Hitchin, John Day, Scott Coleman, Colleen Noviello, Jerome Bouchet, Alexandre Benmerah, John Guatelli, and Serge Benichou: Nef-induced Alteration of the Early/Recycling Endosomal Compartment Correlates with Enhancement of HIV-1 Infectivity
J. Biol. Chem. 2005 280: 5032-5044. First Published on November 29, 2004; doi:10.1074/jbc.M401202200 [Abstract] [Full Text] [PDF]

Weiping Han, Jeong-Seop Rhee, Anton Maximov, Weichun Lin, Robert E. Hammer, Christian Rosenmund, and Thomas C. Südhof: C-terminal ECFP Fusion Impairs Synaptotagmin 1 Function: CROWDING OUT SYNAPTOTAGMIN 1
J. Biol. Chem. 2005 280: 5089-5100. First Published on November 23, 2004; doi:10.1074/jbc.M408757200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Juan Guinea Viniegra, Natalia Martínez, Pegah Modirassari, Javier Hernández Losa, Carlos Parada Cobo, Víctor Javier Sánchez-Arévalo Lobo, Clara Isabel Aceves Luquero, Luis Álvarez-Vallina, Santiago Ramón y Cajal, José María Rojas, and Ricardo Sánchez-Prieto: Full Activation of PKB/Akt in Response to Insulin or Ionizing Radiation Is Mediated through ATM
J. Biol. Chem. 2005 280: 4029-4036. First Published on November 15, 2004; doi:10.1074/jbc.M410344200 [Abstract] [Full Text] [PDF]

Barbara J. Johnson, Thuy T. T. Le, Caroline A. Dobbin, Tatjana Banovic, Christopher B. Howard, Flor de Maria Leon Flores, Daina Vanags, Dean J. Naylor, Geoffrey R. Hill, and Andreas Suhrbier: Heat Shock Protein 10 Inhibits Lipopolysaccharide-induced Inflammatory Mediator Production
J. Biol. Chem. 2005 280: 4037-4047. First Published on November 16, 2004; doi:10.1074/jbc.M411569200 [Abstract] [Full Text] [PDF]

Vasantha Kolachala, Vivian Asamoah, Lixin Wang, Shanthi Srinivasan, Didier Merlin, and Shanthi V. Sitaraman: Interferon- ${gamma}$ Down-regulates Adenosine 2b Receptor-mediated Signaling and Short Circuit Current in the Intestinal Epithelia by Inhibiting the Expression of Adenylate Cyclase
J. Biol. Chem. 2005 280: 4048-4057. First Published on November 18, 2004; doi:10.1074/jbc.M409577200 [Abstract] [Full Text] [PDF]

Dongwoo Shin and Eduardo A. Groisman: Signal-dependent Binding of the Response Regulators PhoP and PmrA to Their Target Promoters in Vivo
J. Biol. Chem. 2005 280: 4089-4094. First Published on November 29, 2004; doi:10.1074/jbc.M412741200 [Abstract] [Full Text] [PDF]

Wei Wu, Travis Pew, Min Zou, Diana Pang, and Suzanne D. Conzen: Glucocorticoid Receptor-induced MAPK Phosphatase-1 (MPK-1) Expression Inhibits Paclitaxel-associated MAPK Activation and Contributes to Breast Cancer Cell Survival
J. Biol. Chem. 2005 280: 4117-4124. First Published on December 7, 2004; doi:10.1074/jbc.M411200200 [Abstract] [Full Text] [PDF]

Kirsti Hill, Sonja Krugmann, Simon R. Andrews, W. John Coadwell, Peter Finan, Heidi C. E. Welch, Phillip T. Hawkins, and Len R. Stephens: Regulation of P-Rex1 by Phosphatidylinositol (3,4,5)-Trisphosphate and G ${beta}$ ${gamma}$ Subunits
J. Biol. Chem. 2005 280: 4166-4173. First Published on November 15, 2004; doi:10.1074/jbc.M411262200 [Abstract] [Full Text] [PDF]

A. Paul Mould, Mark A. Travis, Stephanie J. Barton, Jennifer A. Hamilton, Janet A. Askari, Susan E. Craig, Philip R. MacDonald, Richard A. Kammerer, Patrick A. Buckley, and Martin J. Humphries: Evidence That Monoclonal Antibodies Directed against the Integrin ${beta}$ Subunit Plexin/Semaphorin/Integrin Domain Stimulate Function by Inducing Receptor Extension
J. Biol. Chem. 2005 280: 4238-4246. First Published on November 22, 2004; doi:10.1074/jbc.M412240200 [Abstract] [Full Text] [PDF]

Sally J. York, Blaine N. Armbruster, Patricia Greenwell, Thomas D. Petes, and John D. York: Inositol Diphosphate Signaling Regulates Telomere Length
J. Biol. Chem. 2005 280: 4264-4269. First Published on November 23, 2004; doi:10.1074/jbc.M412070200 [Abstract] [Full Text] [PDF]

Chaitali Basak, Sushil Kumar Pathak, Asima Bhattacharyya, Debabrata Mandal, Shresh Pathak, and Manikuntala Kundu: NF- ${kappa}$ B- and C/EBP ${beta}$ -driven Interleukin-1 ${beta}$ Gene Expression and PAK1-mediated Caspase-1 Activation Play Essential Roles in Interleukin-1 ${beta}$ Release from Helicobacter pylori Lipopolysaccharide-stimulated Macrophages
J. Biol. Chem. 2005 280: 4279-4288. First Published on November 23, 2004; doi:10.1074/jbc.M412820200 [Abstract] [Full Text] [PDF]

Guoxiang Yuan, Jayasri Nanduri, C. Raman Bhasker, Gregg L. Semenza, and Nanduri R. Prabhakar: Ca²⁺/Calmodulin Kinase-dependent Activation of Hypoxia Inducible Factor 1 Transcriptional Activity in Cells Subjected to Intermittent Hypoxia
J. Biol. Chem. 2005 280: 4321-4328. First Published on November 29, 2004; doi:10.1074/jbc.M407706200 [Abstract] [Full Text] [PDF]

Shujuan Chen, Theresa Operaña, Jessica Bonzo, Nghia Nguyen, and Robert H. Tukey: ERK Kinase Inhibition Stabilizes the Aryl Hydrocarbon Receptor: IMPLICATIONS FOR TRANSCRIPTIONAL ACTIVATION AND PROTEIN DEGRADATION
J. Biol. Chem. 2005 280: 4350-4359. First Published on November 29, 2004; doi:10.1074/jbc.M411554200 [Abstract] [Full Text] [PDF]

Tao Wang, Dajing Xia, Nan Li, Chunmei Wang, Taoyong Chen, Tao Wan, Guoyou Chen, and Xuetao Cao: Bone Marrow Stromal Cell-derived Growth Inhibitor Inhibits Growth and Migration of Breast Cancer Cells via Induction of Cell Cycle Arrest and Apoptosis
J. Biol. Chem. 2005 280: 4374-4382. First Published on November 29, 2004; doi:10.1074/jbc.M408708200 [Abstract] [Full Text] [PDF]

Ziva Liberman and Hagit Eldar-Finkelman: Serine 332 Phosphorylation of Insulin Receptor Substrate-1 by Glycogen Synthase Kinase-3 Attenuates Insulin Signaling
J. Biol. Chem. 2005 280: 4422-4428. First Published on November 30, 2004; doi:10.1074/jbc.M410610200 [Abstract] [Full Text] [PDF]

Amos M. Sakwe, Lars Rask, and Erik Gylfe: Protein Kinase C Modulates Agonist-sensitive Release of Ca²⁺ from Internal Stores in HEK293 Cells Overexpressing the Calcium Sensing Receptor
J. Biol. Chem. 2005 280: 4436-4441. First Published on November 30, 2004; doi:10.1074/jbc.M411686200 [Abstract] [Full Text] [PDF]

Nigel J. Waterhouse, Karin A. Sedelies, Kylie A. Browne, Michelle E. Wowk, Andrea Newbold, Vivien R. Sutton, Chris J. P Clarke, Jane Oliaro, Ralph K. Lindemann, Phillip I. Bird, Ricky W. Johnstone, and Joseph A. Trapani: A Central Role for Bid in Granzyme B-induced Apoptosis
J. Biol. Chem. 2005 280: 4476-4482. First Published on December 1, 2004; doi:10.1074/jbc.M410985200 [Abstract] [Full Text] [PDF]

Maria Simon, Lesley Vanes, Robert L. Geahlen, and Victor L. J. Tybulewicz: Distinct Roles for the Linker Region Tyrosines of Syk in Fc ${epsilon}$ RI Signaling in Primary Mast Cells
J. Biol. Chem. 2005 280: 4510-4517. First Published on December 2, 2004; doi:10.1074/jbc.M410326200 [Abstract] [Full Text] [PDF]

Kohsuke Kanekura, Yuichi Hashimoto, Yoshiko Kita, Jumpei Sasabe, Sadakazu Aiso, Ikuo Nishimoto, and Masaaki Matsuoka: A Rac1/Phosphatidylinositol 3-Kinase/Akt3 Anti-apoptotic Pathway, Triggered by AlsinLF, the Product of the ALS2 Gene, Antagonizes Cu/Zn-superoxide Dismutase (SOD1) Mutant-induced Motoneuronal Cell Death
J. Biol. Chem. 2005 280: 4532-4543. First Published on December 3, 2004; doi:10.1074/jbc.M410508200 [Abstract] [Full Text] [PDF]

Bysani Chandrasekar, Srinivas Mummidi, William C. Claycomb, Ruben Mestril, and Mona Nemer: Interleukin-18 Is a Pro-hypertrophic Cytokine That Acts through a Phosphatidylinositol 3-Kinase-Phosphoinositide-dependent Kinase-1-Akt-GATA4 Signaling Pathway in Cardiomyocytes
J. Biol. Chem. 2005 280: 4553-4567. First Published on December 1, 2004; doi:10.1074/jbc.M411787200 [Abstract] [Full Text] [PDF]

Sophie Mouillet-Richard, Mathéa Pietri, Benoît Schneider, Catherine Vidal, Vincent Mutel, Jean-Marie Launay, and Odile Kellermann: Modulation of Serotonergic Receptor Signaling and Cross-talk by Prion Protein
J. Biol. Chem. 2005 280: 4592-4601. First Published on December 8, 2004; doi:10.1074/jbc.M406199200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gabriela M. Wochnik, Joëlle Rüegg, G. Alexander Abel, Ulrike Schmidt, Florian Holsboer, and Theo Rein: FK506-binding Proteins 51 and 52 Differentially Regulate Dynein Interaction and Nuclear Translocation of the Glucocorticoid Receptor in Mammalian Cells
J. Biol. Chem. 2005 280: 4609-4616. First Published on December 9, 2004; doi:10.1074/jbc.M407498200 [Abstract] [Full Text] [PDF]

Jin-Ran Chen, Lilian I. Plotkin, José Ignacio Aguirre, Li Han, Robert L. Jilka, Stavroula Kousteni, Teresita Bellido, and Stavros C. Manolagas: Transient Versus Sustained Phosphorylation and Nuclear Accumulation of ERKs Underlie Anti-Versus Pro-apoptotic Effects of Estrogens
J. Biol. Chem. 2005 280: 4632-4638. First Published on November 22, 2004; doi:10.1074/jbc.M411530200 [Abstract] [Full Text] [PDF]

Estelle Dransart, Annie Morin, Jacqueline Cherfils, and Birgitta Olofsson: Uncoupling of Inhibitory and Shuttling Functions of Rho GDP Dissociation Inhibitors
J. Biol. Chem. 2005 280: 4674-4683. First Published on October 28, 2004; doi:10.1074/jbc.M409741200 [Abstract] [Full Text] [PDF]

Eric M. Grund, Demetri D. Spyropoulos, Dennis K. Watson, and Robin C. Muise-Helmericks: Interleukins 2 and 15 Regulate Ets1 Expression via ERK1/2 and MNK1 in Human Natural Killer Cells
J. Biol. Chem. 2005 280: 4772-4778. First Published on November 23, 2004; doi:10.1074/jbc.M408356200 [Abstract] [Full Text] [PDF]

Junko Naito, Hiroshi Kaji, Hideaki Sowa, Geoffrey N. Hendy, Toshitsugu Sugimoto, and Kazuo Chihara: Menin Suppresses Osteoblast Differentiation by Antagonizing the AP-1 Factor, JunD
J. Biol. Chem. 2005 280: 4785-4791. First Published on November 23, 2004; doi:10.1074/jbc.M408143200 [Abstract] [Full Text] [PDF]

Filipa Lopes de Mendonça, Paula C. A. da Fonseca, Rhian M. Phillips, José W. Saldanha, Timothy J. Williams, and James E. Pease: Site-directed Mutagenesis of CC Chemokine Receptor 1 Reveals the Mechanism of Action of UCB 35625, a Small Molecule Chemokine Receptor Antagonist
J. Biol. Chem. 2005 280: 4808-4816. First Published on November 17, 2004; doi:10.1074/jbc.M412267200 [Abstract] [Full Text] [PDF]

Maocheng Zhan, Dihua Yu, Juehui Liu, Jonathan Hannay, and Raphael E. Pollock: Transcriptional Repression of Protein Kinase C ${alpha}$ via Sp1 by Wild Type p53 Is Involved in Inhibition of Multidrug Resistance 1 P-Glycoprotein Phosphorylation
J. Biol. Chem. 2005 280: 4825-4833. First Published on November 24, 2004; doi:10.1074/jbc.M407450200 [Abstract] [Full Text] [PDF]

Venkatakrishna R. Jala, Wen-Hai Shao, and Bodduluri Haribabu: Phosphorylation-independent ${beta}$ -Arrestin Translocation and Internalization of Leukotriene B₄ Receptors
J. Biol. Chem. 2005 280: 4880-4887. First Published on November 23, 2004; doi:10.1074/jbc.M409821200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Eun-Joo Kim, Jong-In Park, and Barry D. Nelkin: IFI16 Is an Essential Mediator of Growth Inhibition, but Not Differentiation, Induced by the Leukemia Inhibitory Factor/JAK/STAT Pathway in Medullary Thyroid Carcinoma Cells
J. Biol. Chem. 2005 280: 4913-4920. First Published on November 30, 2004; doi:10.1074/jbc.M410542200 [Abstract] [Full Text] [PDF]

Yasuhiko Koga and Mitsuo Ikebe: p116^Rip Decreases Myosin II Phosphorylation by Activating Myosin Light Chain Phosphatase and by Inactivating RhoA
J. Biol. Chem. 2005 280: 4983-4991. First Published on November 14, 2004; doi:10.1074/jbc.M410909200 [Abstract] [Full Text] [PDF]

Mitsuru Ohsugi, Corentin Cras-Méneur, Yiyong Zhou, Ernesto Bernal-Mizrachi, James D. Johnson, Dan S. Luciani, Kenneth S. Polonsky, and M. Alan Permutt: Reduced Expression of the Insulin Receptor in Mouse Insulinoma (MIN6) Cells Reveals Multiple Roles of Insulin Signaling in Gene Expression, Proliferation, Insulin Content, and Secretion
J. Biol. Chem. 2005 280: 4992-5003. First Published on November 15, 2004; doi:10.1074/jbc.M411727200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hisakazu Fujita, Shigetomo Fukuhara, Atsuko Sakurai, Akiko Yamagishi, Yuji Kamioka, Yoshikazu Nakaoka, Michitaka Masuda, and Naoki Mochizuki: Local Activation of Rap1 Contributes to Directional Vascular Endothelial Cell Migration Accompanied by Extension of Microtubules on Which RAPL, a Rap1-associating Molecule, Localizes
J. Biol. Chem. 2005 280: 5022-5031. First Published on November 29, 2004; doi:10.1074/jbc.M409701200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Wen Luo, Haiying Zou, Lihua Jin, Shuyong Lin, Qinxi Li, Zhiyun Ye, Hongliang Rui, and Sheng-Cai Lin: Axin Contains Three Separable Domains That Confer Intramolecular, Homodimeric, and Heterodimeric Interactions Involved in Distinct Functions
J. Biol. Chem. 2005 280: 5054-5060. First Published on December 5, 2004; doi:10.1074/jbc.M412340200 [Abstract] [Full Text] [PDF]

Jianxin Hu, Stuart J. McLarnon, Stefano Mora, Jiankang Jiang, Craig Thomas, Kenneth A. Jacobson, and Allen M. Spiegel: A Region in the Seven-transmembrane Domain of the Human Ca²⁺ Receptor Critical for Response to Ca²⁺
J. Biol. Chem. 2005 280: 5113-5120. First Published on December 9, 2004; doi:10.1074/jbc.M413403200 [Abstract] [Full Text] [PDF]

Philipp Voigt, Carsten Brock, Bernd Nürnberg, and Michael Schaefer: Assigning Functional Domains within the p101 Regulatory Subunit of Phosphoinositide 3-Kinase ${gamma}$
J. Biol. Chem. 2005 280: 5121-5127. First Published on December 20, 2004; doi:10.1074/jbc.M413104200 [Abstract] [Full Text] [PDF] [Suplemental Data] [Summary]

Molecular Basis Of Cell and Developmental Biology:

Hisanori Kurooka and Yoshifumi Yokota: Nucleo-cytoplasmic Shuttling of Id2, a Negative Regulator of Basic Helix-Loop-Helix Transcription Factors
J. Biol. Chem. 2005 280: 4313-4320. First Published on November 24, 2004; doi:10.1074/jbc.M412614200 [Abstract] [Full Text] [PDF]

Jay H. Chyung, Daniel M. Raper, and Dennis J. Selkoe: ${gamma}$ -Secretase Exists on the Plasma Membrane as an Intact Complex That Accepts Substrates and Effects Intramembrane Cleavage
J. Biol. Chem. 2005 280: 4383-4392. First Published on November 29, 2004; doi:10.1074/jbc.M409272200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Cataldo Arcuri, Roberta Bianchi, Flora Brozzi, and Rosario Donato: S100B Increases Proliferation in PC12 Neuronal Cells and Reduces Their Responsiveness to Nerve Growth Factor via Akt Activation
J. Biol. Chem. 2005 280: 4402-4414. First Published on November 30, 2004; doi:10.1074/jbc.M406440200 [Abstract] [Full Text] [PDF]

Nicholas E. Vlahakis, Bradford A. Young, Amha Atakilit, and Dean Sheppard: The Lymphangiogenic Vascular Endothelial Growth Factors VEGF-C and -D Are Ligands for the Integrin ${alpha}$ 9 ${beta}$ 1
J. Biol. Chem. 2005 280: 4544-4552. First Published on December 6, 2004; doi:10.1074/jbc.M412816200 [Abstract] [Full Text] [PDF]

Colin Adrain, Brona M. Murphy, and Seamus J. Martin: Molecular Ordering of the Caspase Activation Cascade Initiated by the Cytotoxic T Lymphocyte/Natural Killer (CTL/NK) Protease Granzyme B
J. Biol. Chem. 2005 280: 4663-4673. First Published on November 29, 2004; doi:10.1074/jbc.M410915200 [Abstract] [Full Text] [PDF]

Mikiro Takaishi, Teruhiko Makino, Masaaki Morohashi, and Nam-ho Huh: Identification of Human Hornerin and Its Expression in Regenerating and Psoriatic Skin
J. Biol. Chem. 2005 280: 4696-4703. First Published on October 26, 2004; doi:10.1074/jbc.M409026200 [Abstract] [Full Text] [PDF]

Feng Yin and B. Paul Herring: GATA-6 Can Act as a Positive or Negative Regulator of Smooth Muscle-specific Gene Expression
J. Biol. Chem. 2005 280: 4745-4752. First Published on November 18, 2004; doi:10.1074/jbc.M411585200 [Abstract] [Full Text] [PDF]

Clara Martinez-Rico, Frederic Pincet, Eric Perez, Jean Paul Thiery, Kazuya Shimizu, Yoshimi Takai, and Sylvie Dufour: Separation Force Measurements Reveal Different Types of Modulation of E-cadherin-based Adhesion by Nectin-1 and -3
J. Biol. Chem. 2005 280: 4753-4760. First Published on November 18, 2004; doi:10.1074/jbc.M412544200 [Abstract] [Full Text] [PDF]

Marie-Josée Lacombe, Chantal Mercure, Jimmy D. Dikeakos, and Timothy L. Reudelhuber: Modulation of Secretory Granule-targeting Efficiency by Cis and Trans Compounding of Sorting Signals
J. Biol. Chem. 2005 280: 4803-4807. First Published on November 29, 2004; doi:10.1074/jbc.M408658200 [Abstract] [Full Text] [PDF]

Jining Lü, Konstantin I. Izvolsky, Jun Qian, and Wellington V. Cardoso: Identification of FGF10 Targets in the Embryonic Lung Epithelium during Bud Morphogenesis
J. Biol. Chem. 2005 280: 4834-4841. First Published on November 19, 2004; doi:10.1074/jbc.M410714200 [Abstract] [Full Text] [PDF]

Xiaobing Deng, Daina Z. Ewton, Stephen E. Mercer, and Eileen Friedman: Mirk/dyrk1B Decreases the Nuclear Accumulation of Class II Histone Deacetylases during Skeletal Muscle Differentiation
J. Biol. Chem. 2005 280: 4894-4905. First Published on November 16, 2004; doi:10.1074/jbc.M411894200 [Abstract] [Full Text] [PDF]

Eri Ishiko, Itaru Matsumura, Sachiko Ezoe, Karin Gale, Jun Ishiko, Yusuke Satoh, Hirokazu Tanaka, Hirohiko Shibayama, Masao Mizuki, Takumi Era, Tariq Enver, and Yuzuru Kanakura: Notch Signals Inhibit the Development of Erythroid/Megakaryocytic Cells by Suppressing GATA-1 Activity through the Induction of HES1
J. Biol. Chem. 2005 280: 4929-4939. First Published on November 24, 2004; doi:10.1074/jbc.M406788200 [Abstract] [Full Text] [PDF]

Tomomi Kawakatsu, Hisakazu Ogita, Tatsuro Fukuhara, Taihei Fukuyama, Yukiko Minami, Kazuya Shimizu, and Yoshimi Takai: Vav2 as a Rac-GDP/GTP Exchange Factor Responsible for the Nectin-induced, c-Src- and Cdc42-mediated Activation of Rac
J. Biol. Chem. 2005 280: 4940-4947. First Published on October 13, 2004; doi:10.1074/jbc.M408710200 [Abstract] [Full Text] [PDF]

Irina V. Nesmelova, Yuk Sham, Arkadiusz Z. Dudek, Loes I. van Eijk, Guoping Wu, Arne Slungaard, Frank Mortari, Arjan W. Griffioen, and Kevin H. Mayo: Platelet Factor 4 and Interleukin-8 CXC Chemokine Heterodimer Formation Modulates Function at the Quaternary Structural Level
J. Biol. Chem. 2005 280: 4948-4958. First Published on November 5, 2004; doi:10.1074/jbc.M405364200 [Abstract] [Full Text] [PDF]

Hongyun She, Shigang Xiong, Saswati Hazra, and Hidekazu Tsukamoto: Adipogenic Transcriptional Regulation of Hepatic Stellate Cells
J. Biol. Chem. 2005 280: 4959-4967. First Published on November 9, 2004; doi:10.1074/jbc.M410078200 [Abstract] [Full Text] [PDF]

Daijiro Konno, Saori Yoshimura, Kei Hori, Hisato Maruoka, and Kenji Sobue: Involvement of the Phosphatidylinositol 3-Kinase/Rac1 and Cdc42 Pathways in Radial Migration of Cortical Neurons
J. Biol. Chem. 2005 280: 5082-5088. First Published on November 22, 2004; doi:10.1074/jbc.M408251200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Yuanming Hu, Cindy Leo, Simon Yu, Betty C. B. Huang, Hank Wang, Mary Shen, Ying Luo, Sarkiz Daniel-Issakani, Donald G. Payan, and Xiang Xu: Identification and functional characterization of a novel human Misshapen/Nck interacting kinase-related kinase, hMINK ${beta}$ . Vol. 279 (2004) 54387–54397
J. Biol. Chem. 2005 280: 5128. [Full Text] [PDF]