JBC -- Table of Contents (Feb 18 2005, 280, (7))

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Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Lyman Creighton Craig: Developer of the Counter-current Distribution Method
IDENTIFICATION OF SMALL AMOUNTS OF ORGANIC COMPOUNDS BY DISTRIBUTION STUDIES. APPLICATION TO ATABRINE (Lyman C. Craig J. Biol. Chem. 150, 33-45)
IDENTIFICATION OF SMALL AMOUNTS OF ORGANIC COMPOUNDS BY DISTRIBUTION STUDIES. II. SEPARATION BY COUNTER-CURRENT DISTRIBUTION (Lyman C. Craig J. Biol. Chem. 155, 519-534)
J. Biol. Chem. 2005 280: e4. [Full Text]

Minireviews:

Blaine N. Armbruster and Bryan L. Roth: Mining the Receptorome
J. Biol. Chem. 2005 280: 5129-5132. First Published on December 8, 2004; doi:10.1074/jbc.R400030200 [Full Text] [PDF] [Supplemental Data]

Accelerated Publications:

Kirill A. Martemyanov, Peter J. Yoo, Nikolai P. Skiba, and Vadim Y. Arshavsky: R7BP, a Novel Neuronal Protein Interacting with RGS Proteins of the R7 Family
J. Biol. Chem. 2005 280: 5133-5136. First Published on January 4, 2005; doi:10.1074/jbc.C400596200 [Abstract] [Full Text] [PDF]

Armgard Uelhoff, Jörg Tatzelt, Adriano Aguzzi, Konstanze F. Winklhofer, and Christian Haass: A Pathogenic PrP Mutation and Doppel Interfere with Polarized Sorting of the Prion Protein
J. Biol. Chem. 2005 280: 5137-5140. First Published on December 21, 2004; doi:10.1074/jbc.C400560200 [Abstract] [Full Text] [PDF]

Bidesh Mahata, Suvendra Nath Bhattacharyya, Saikat Mukherjee, and Samit Adhya: Correction of Translational Defects in Patient-derived Mutant Mitochondria by Complex-mediated Import of a Cytoplasmic tRNA
J. Biol. Chem. 2005 280: 5141-5144. First Published on December 24, 2004; doi:10.1074/jbc.C400572200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Catherine L. Bladen, Durga Udayakumar, Yoshihiko Takeda, and William S. Dynan: Identification of the Polypyrimidine Tract Binding Protein-associated Splicing Factor·p54(nrb) Complex as a Candidate DNA Double-strand Break Rejoining Factor
J. Biol. Chem. 2005 280: 5205-5210. First Published on December 7, 2004; doi:10.1074/jbc.M412758200 [Abstract] [Full Text] [PDF]

Jeffrey G. Mandell, Karen J. Goodrich, Jürg Bähler, and Thomas R. Cech: Expression of a RecQ Helicase Homolog Affects Progression through Crisis in Fission Yeast Lacking Telomerase
J. Biol. Chem. 2005 280: 5249-5257. First Published on December 8, 2004; doi:10.1074/jbc.M412756200 [Abstract] [Full Text] [PDF]

Wensheng Wang and Robert A. Bambara: Human Bloom Protein Stimulates Flap Endonuclease 1 Activity by Resolving DNA Secondary Structure
J. Biol. Chem. 2005 280: 5391-5399. First Published on December 4, 2004; doi:10.1074/jbc.M412359200 [Abstract] [Full Text] [PDF]

Mark Meyers, Mark W. Wagner, Anthony Mazurek, Christoph Schmutte, Richard Fishel, and David A. Boothman: DNA Mismatch Repair-dependent Response to Fluoropyrimidine-generated Damage
J. Biol. Chem. 2005 280: 5516-5526. First Published on December 14, 2004; doi:10.1074/jbc.M412105200 [Abstract] [Full Text] [PDF]

Markus Böhm, Ilka Wolff, Thomas E. Scholzen, Samantha J. Robinson, Eugene Healy, Thomas A. Luger, Thomas Schwarz, and Agatha Schwarz: ${alpha}$ -Melanocyte-stimulating Hormone Protects from Ultraviolet Radiation-induced Apoptosis and DNA Damage
J. Biol. Chem. 2005 280: 5795-5802. First Published on November 29, 2004; doi:10.1074/jbc.M406334200 [Abstract] [Full Text] [PDF]

Zhiqi Yin, Makkuni Jayaram, Shailja Pathania, and Rasika M. Harshey: The Mu Transposase Interwraps Distant DNA Sites within a Functional Transpososome in the Absence of DNA Supercoiling
J. Biol. Chem. 2005 280: 6149-6156. First Published on November 24, 2004; doi:10.1074/jbc.M411679200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Minna Novoseler, Gitit Hershkovits, and Don J. Katcoff: Functional Domains of the Yeast Chromatin Protein Sin1p/Spt2p Can Bind Four-way Junction and Crossing DNA Structures
J. Biol. Chem. 2005 280: 5169-5177. First Published on November 24, 2004; doi:10.1074/jbc.M406249200 [Abstract] [Full Text] [PDF]

Thomas J. Lie, Gwendolyn E. Wood, and John A. Leigh: Regulation of nif Expression in Methanococcus maripaludis: ROLES OF THE EURYARCHAEAL REPRESSOR NrpR, 2-OXOGLUTARATE, AND TWO OPERATORS
J. Biol. Chem. 2005 280: 5236-5241. First Published on December 7, 2004; doi:10.1074/jbc.M411778200 [Abstract] [Full Text] [PDF]

Maria B. Sandberg, Maria Bloksgaard, Daniel Duran-Sandoval, Caroline Duval, Bart Staels, and Susanne Mandrup: The Gene Encoding Acyl-CoA-binding Protein Is Subject to Metabolic Regulation by Both Sterol Regulatory Element-binding Protein and Peroxisome Proliferator-activated Receptor ${alpha}$ in Hepatocytes
J. Biol. Chem. 2005 280: 5258-5266. First Published on December 15, 2004; doi:10.1074/jbc.M407515200 [Abstract] [Full Text] [PDF]

Mario Bermúdez de León, Cecilia Montañez, Pablo Gómez, Sara Luz Morales-Lázaro, Victor Tapia-Ramírez, Viviana Valadez-Graham, Félix Recillas-Targa, David Yaffe, Uri Nudel, and Bulmaro Cisneros: Dystrophin Dp71 Expression Is Down-regulated during Myogenesis: ROLE OF Sp1 AND Sp3 ON THE Dp71 PROMOTER ACTIVITY
J. Biol. Chem. 2005 280: 5290-5299. First Published on November 18, 2004; doi:10.1074/jbc.M411571200 [Abstract] [Full Text] [PDF]

Mingjun Liu, Yubin Ge, Diane C. Cabelof, Amro Aboukameel, Ahmad R. Heydari, Ramzi Mohammad, and Larry H. Matherly: Structure and Regulation of the Murine Reduced Folate Carrier Gene: IDENTIFICATION OF FOUR NONCODING EXONS AND PROMOTERS AND REGULATION BY DIETARY FOLATES
J. Biol. Chem. 2005 280: 5588-5597. First Published on December 3, 2004; doi:10.1074/jbc.M412662200 [Abstract] [Full Text] [PDF]

James Garnon, Claude Lachance, Sergio Di Marco, Zdenek Hel, Dominique Marion, Maria C. Ruiz, Marianna M. Newkirk, Edouard W. Khandjian, and Danuta Radzioch: Fragile X-related Protein FXR1P Regulates Proinflammatory Cytokine Tumor Necrosis Factor Expression at the Post-transcriptional Level
J. Biol. Chem. 2005 280: 5750-5763. First Published on November 17, 2004; doi:10.1074/jbc.M401988200 [Abstract] [Full Text] [PDF]

So-Young Oh, Min-Young Lee, Jong-Min Kim, Sarah Yoon, Soonah Shin, Young Nyun Park, Yong-Ho Ahn, and Kyung-Sup Kim: Alternative Usages of Multiple Promoters of the Acetyl-CoA Carboxylase ${beta}$ Gene Are Related to Differential Transcriptional Regulation in Human and Rodent Tissues
J. Biol. Chem. 2005 280: 5909-5916. First Published on December 6, 2004; doi:10.1074/jbc.M409037200 [Abstract] [Full Text] [PDF]

Marcella Flinterman, Lars Guelen, Samira Ezzati-Nik, Richard Killick, Gerry Melino, Kazuya Tominaga, Joe S. Mymryk, Joop Gäken, and Mahvash Tavassoli: E1A Activates Transcription of p73 and Noxa to Induce Apoptosis
J. Biol. Chem. 2005 280: 5945-5959. First Published on November 29, 2004; doi:10.1074/jbc.M406661200 [Abstract] [Full Text] [PDF]

Shu-Xia Wang, Paula K. Elder, Ye Zheng, Arthur R. Strauch, and Robert J. Kelm, Jr.: Cell Cycle-mediated Regulation of Smooth Muscle ${alpha}$ -Actin Gene Transcription in Fibroblasts and Vascular Smooth Muscle Cells Involves Multiple Adenovirus E1A-interacting Cofactors
J. Biol. Chem. 2005 280: 6204-6214. First Published on December 2, 2004; doi:10.1074/jbc.M409506200 [Abstract] [Full Text] [PDF]

Siv Gilfillan, Gertraud Stelzer, Elisa Piaia, Markus G. Hofmann, and Michael Meisterernst: Efficient Binding of NC2·TATA-binding Protein to DNA in the Absence of TATA
J. Biol. Chem. 2005 280: 6222-6230. First Published on November 30, 2004; doi:10.1074/jbc.M406343200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Thorarinn Blondal, Sigridur Hjorleifsdottir, Arnthor Aevarsson, Olafur H. Fridjonsson, Sigurlaug Skirnisdottir, Jon Oskar Wheat, Anna Gudny Hermannsdottir, Gudmundur O. Hreggvidsson, Albert Vernon Smith, and Jakob K. Kristjansson: Characterization of a 5'-Polynucleotide Kinase/3'-Phosphatase from Bacteriophage RM378
J. Biol. Chem. 2005 280: 5188-5194. First Published on December 2, 2004; doi:10.1074/jbc.M409211200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Tetsuaki Arai, Jian-Ping Guo, and Patrick L. McGeer: Proteolysis of Non-phosphorylated and Phosphorylated Tau by Thrombin
J. Biol. Chem. 2005 280: 5145-5153. First Published on November 12, 2004; doi:10.1074/jbc.M409234200 [Abstract] [Full Text] [PDF]

Stephen D. Waterford, Thomas R. Kolodecik, Edwin C. Thrower, and Fred S. Gorelick: Vacuolar ATPase Regulates Zymogen Activation in Pancreatic Acini
J. Biol. Chem. 2005 280: 5430-5434. First Published on December 6, 2004; doi:10.1074/jbc.M413513200 [Abstract] [Full Text] [PDF]

Mélina L. Heuzé, Florence C. Guibal, Charles A. Banks, Joan W. Conaway, Ronald C. Conaway, Yvon E. Cayre, Arndt Benecke, and Pierre G. Lutz: ASB2 Is an Elongin BC-interacting Protein That Can Assemble with Cullin 5 and Rbx1 to Reconstitute an E3 Ubiquitin Ligase Complex
J. Biol. Chem. 2005 280: 5468-5474. First Published on December 8, 2004; doi:10.1074/jbc.M413040200 [Abstract] [Full Text] [PDF]

Yannick Jacob, Stephen M. Sharkady, Kanchan Bhardwaj, Alina Sanda, and Kelly P. Williams: Function of the SmpB Tail in Transfer-messenger RNA Translation Revealed by a Nucleus-encoded Form
J. Biol. Chem. 2005 280: 5503-5509. First Published on December 13, 2004; doi:10.1074/jbc.M409277200 [Abstract] [Full Text] [PDF]

Bradley A. Carlson, Xue-Ming Xu, Vadim N. Gladyshev, and Dolph L. Hatfield: Selective Rescue of Selenoprotein Expression in Mice Lacking a Highly Specialized Methyl Group in Selenocysteine tRNA
J. Biol. Chem. 2005 280: 5542-5548. First Published on December 17, 2004; doi:10.1074/jbc.M411725200 [Abstract] [Full Text] [PDF]

Hidehisa Takahashi, Shigetsugu Hatakeyama, Hisato Saitoh, and Keiichi I. Nakayama: Noncovalent SUMO-1 Binding Activity of Thymine DNA Glycosylase (TDG) Is Required for Its SUMO-1 Modification and Colocalization with the Promyelocytic Leukemia Protein
J. Biol. Chem. 2005 280: 5611-5621. First Published on November 29, 2004; doi:10.1074/jbc.M408130200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Naila Ahmed, Darin Dobler, Mark Dean, and Paul J. Thornalley: Peptide Mapping Identifies Hotspot Site of Modification in Human Serum Albumin by Methylglyoxal Involved in Ligand Binding and Esterase Activity
J. Biol. Chem. 2005 280: 5724-5732. First Published on November 22, 2004; doi:10.1074/jbc.M410973200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Solange Desagher, Dany Severac, Alexey Lipkin, Cyril Bernis, William Ritchie, Anne Le Digarcher, and Laurent Journot: Genes Regulated in Neurons Undergoing Transcription-dependent Apoptosis Belong to Signaling Pathways Rather than the Apoptotic Machinery
J. Biol. Chem. 2005 280: 5693-5702. First Published on November 12, 2004; doi:10.1074/jbc.M408971200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mark O. Collins, Lu Yu, Marcelo P. Coba, Holger Husi, Iain Campuzano, Walter P. Blackstock, Jyoti S. Choudhary, and Seth G. N. Grant: Proteomic Analysis of in Vivo Phosphorylated Synaptic Proteins
J. Biol. Chem. 2005 280: 5972-5982. First Published on November 30, 2004; doi:10.1074/jbc.M411220200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sanjoy K. Bhattacharya, Edward J. Rockwood, Scott D. Smith, Vera L. Bonilha, John S. Crabb, Rachel W. Kuchtey, Nahid G. Robertson, Neal S. Peachey, Cynthia C. Morton, and John W. Crabb: Proteomics Reveal Cochlin Deposits Associated with Glaucomatous Trabecular Meshwork
J. Biol. Chem. 2005 280: 6080-6084. First Published on December 3, 2004; doi:10.1074/jbc.M411233200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Peppi Koivunen, Kirsi E. H. Salo, Johanna Myllyharju, and Lloyd W. Ruddock: Three Binding Sites in Protein-disulfide Isomerase Cooperate in Collagen Prolyl 4-Hydroxylase Tetramer Assembly
J. Biol. Chem. 2005 280: 5227-5235. First Published on December 7, 2004; doi:10.1074/jbc.M412480200 [Abstract] [Full Text] [PDF]

R. Shashidharamurthy, Hanane A. Koteiche, Jinhui Dong, and Hassane S. Mchaourab: Mechanism of Chaperone Function in Small Heat Shock Proteins: DISSOCIATION OF THE HSP27 OLIGOMER IS REQUIRED FOR RECOGNITION AND BINDING OF DESTABILIZED T4 LYSOZYME
J. Biol. Chem. 2005 280: 5281-5289. First Published on November 12, 2004; doi:10.1074/jbc.M407236200 [Abstract] [Full Text] [PDF]

Suveena Sharma, Joel R. Hoskins, and Sue Wickner: Binding and Degradation of Heterodimeric Substrates by ClpAP and ClpXP
J. Biol. Chem. 2005 280: 5449-5455. First Published on December 8, 2004; doi:10.1074/jbc.M412411200 [Abstract] [Full Text] [PDF]

Kenta Oikawa, Shota Nakamura, Takafumi Sonoyama, Atsushi Ohshima, Yuji Kobayashi, Shin-ichi J. Takayama, Yasuhiko Yamamoto, Susumu Uchiyama, Jun Hasegawa, and Yoshihiro Sambongi: Five Amino Acid Residues Responsible for the High Stability of Hydrogenobacter thermophilus Cytochrome c₅₅₂: RECIPROCAL MUTATION ANALYSIS
J. Biol. Chem. 2005 280: 5527-5532. First Published on December 14, 2004; doi:10.1074/jbc.M412392200 [Abstract] [Full Text] [PDF]

Hiroshi Hashimoto, Toshiyuki Shimizu, Tsuyoshi Imasaki, Matsuri Kato, Naoki Shichijo, Keiko Kita, and Mamoru Sato: Crystal Structures of Type II Restriction Endonuclease EcoO109I and Its Complex with Cognate DNA
J. Biol. Chem. 2005 280: 5605-5610. First Published on December 7, 2004; doi:10.1074/jbc.M411684200 [Abstract] [Full Text] [PDF]

Fabrice A. C. Klein, R. Andrew Atkinson, Noelle Potier, Dino Moras, and Jean Cavarelli: Biochemical and NMR Mapping of the Interface between CREB-binding Protein and Ligand Binding Domains of Nuclear Receptor: BEYOND THE LXXLL MOTIF
J. Biol. Chem. 2005 280: 5682-5692. First Published on November 12, 2004; doi:10.1074/jbc.M411697200 [Abstract] [Full Text] [PDF]

Evo Lindersson, Ditte Lundvig, Christine Petersen, Peder Madsen, Jens R. Nyengaard, Peter Højrup, Torben Moos, Daniel Otzen, Wei-Ping Gai, Peter C. Blumbergs, and Poul Henning Jensen: p25 ${alpha}$ Stimulates ${alpha}$ -Synuclein Aggregation and Is Co-localized with Aggregated ${alpha}$ -Synuclein in ${alpha}$ -Synucleinopathies
J. Biol. Chem. 2005 280: 5703-5715. First Published on December 7, 2004; doi:10.1074/jbc.M410409200 [Abstract] [Full Text] [PDF]

Stephen R. Shouldice, Duncan E. McRee, Douglas R. Dougan, Leslie W. Tari, and Anthony B. Schryvers: Novel Anion-independent Iron Coordination by Members of a Third Class of Bacterial Periplasmic Ferric Ion-binding Proteins
J. Biol. Chem. 2005 280: 5820-5827. First Published on December 2, 2004; doi:10.1074/jbc.M411238200 [Abstract] [Full Text] [PDF]

Fusheng Yang, Giselle P. Lim, Aynun N. Begum, Oliver J. Ubeda, Mychica R. Simmons, Surendra S. Ambegaokar, Pingping P. Chen, Rakez Kayed, Charles G. Glabe, Sally A. Frautschy, and Gregory M. Cole: Curcumin Inhibits Formation of Amyloid ${beta}$ Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo
J. Biol. Chem. 2005 280: 5892-5901. First Published on December 7, 2004; doi:10.1074/jbc.M404751200 [Abstract] [Full Text] [PDF]

Dewan Andrews, James S. Butler, Jawdat Al-Bassam, Lisa Joss, Danella A. Winn-Stapley, Sherwood Casjens, and Gino Cingolani: Bacteriophage P22 Tail Accessory Factor GP26 Is a Long Triple-stranded Coiled-coil
J. Biol. Chem. 2005 280: 5929-5933. First Published on December 8, 2004; doi:10.1074/jbc.C400513200 [Abstract] [Full Text] [PDF]

Kevin C. Qian, Lian Wang, Eugene R. Hickey, Joey Studts, Kevin Barringer, Charline Peng, Anthony Kronkaitis, Jun Li, Andre White, Sheenah Mische, and Bennett Farmer: Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase
J. Biol. Chem. 2005 280: 6130-6137. First Published on November 3, 2004; doi:10.1074/jbc.M409123200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Kevin Francis, Bethany Russell, and Giovanni Gadda: Involvement of a Flavosemiquinone in the Enzymatic Oxidation of Nitroalkanes Catalyzed by 2-Nitropropane Dioxygenase
J. Biol. Chem. 2005 280: 5195-5204. First Published on December 6, 2004; doi:10.1074/jbc.M411249200 [Abstract] [Full Text] [PDF]

Carsten Wrenger, Marie-Luise Eschbach, Ingrid B. Müller, Dirk Warnecke, and Rolf D. Walter: Analysis of the Vitamin B6 Biosynthesis Pathway in the Human Malaria Parasite Plasmodium falciparum
J. Biol. Chem. 2005 280: 5242-5248. First Published on December 7, 2004; doi:10.1074/jbc.M412475200 [Abstract] [Full Text] [PDF]

Sebastian M. J. Klaus, Arno Wegkamp, Wilbert Sybesma, Jeroen Hugenholtz, Jesse F. Gregory, III, and Andrew D. Hanson: A Nudix Enzyme Removes Pyrophosphate from Dihydroneopterin Triphosphate in the Folate Synthesis Pathway of Bacteria and Plants
J. Biol. Chem. 2005 280: 5274-5280. First Published on December 16, 2004; doi:10.1074/jbc.M413759200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hisashi Muramatsu, Hisaaki Mihara, Ryo Kakutani, Mari Yasuda, Makoto Ueda, Tatsuo Kurihara, and Nobuyoshi Esaki: The Putative Malate/Lactate Dehydrogenase from Pseudomonas putida Is an NADPH-dependent ${Delta}$ ¹-Piperideine-2-carboxylate/ ${Delta}$ ¹-Pyrroline-2-carboxylate Reductase Involved in the Catabolism of D-Lysine and D-Proline
J. Biol. Chem. 2005 280: 5329-5335. First Published on November 23, 2004; doi:10.1074/jbc.M411918200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jonathon Griffin, Christine Roshick, Emma Iliffe-Lee, and Grant McClarty: Catalytic Mechanism of Chlamydia trachomatis Flavin-dependent Thymidylate Synthase
J. Biol. Chem. 2005 280: 5456-5467. First Published on December 8, 2004; doi:10.1074/jbc.M412415200 [Abstract] [Full Text] [PDF]

Katsuaki Kobayashi, Shiro Yoshioka, Yasuo Kato, Yasuhisa Asano, and Shigetoshi Aono: Regulation of Aldoxime Dehydratase Activity by Redox-dependent Change in the Coordination Structure of the Aldoxime-Heme Complex
J. Biol. Chem. 2005 280: 5486-5490. First Published on December 13, 2004; doi:10.1074/jbc.M410474200 [Abstract] [Full Text] [PDF]

Robert E. Collins, Makoto Tachibana, Hisashi Tamaru, Kristina M. Smith, Da Jia, Xing Zhang, Eric U. Selker, Yoichi Shinkai, and Xiaodong Cheng: In Vitro and in Vivo Analyses of a Phe/Tyr Switch Controlling Product Specificity of Histone Lysine Methyltransferases
J. Biol. Chem. 2005 280: 5563-5570. First Published on December 6, 2004; doi:10.1074/jbc.M410483200 [Abstract] [Full Text] [PDF]

Ilka Müller, Claudia Stückl, James Wakeley, Michael Kertesz, and Isabel Usón: Succinate Complex Crystal Structures of the ${alpha}$ -Ketoglutarate-dependent Dioxygenase AtsK: STERIC ASPECTS OF ENZYME SELF-HYDROXYLATION
J. Biol. Chem. 2005 280: 5716-5723. First Published on November 12, 2004; doi:10.1074/jbc.M410840200 [Abstract] [Full Text] [PDF]

Sandra J. Campbell, Colin J. Henderson, Daniel C. Anthony, Duncan Davidson, A. John Clark, and C. Roland Wolf: The Murine Cyp1a1 Gene Is Expressed in a Restricted Spatial and Temporal Pattern during Embryonic Development
J. Biol. Chem. 2005 280: 5828-5835. First Published on November 29, 2004; doi:10.1074/jbc.M412899200 [Abstract] [Full Text] [PDF]

Christian Korn, Sebastian R. Scholz, Oleg Gimadutdinow, Rudi Lurz, Alfred Pingoud, and Gregor Meiss: Interaction of DNA Fragmentation Factor (DFF) with DNA Reveals an Unprecedented Mechanism for Nuclease Inhibition and Suggests That DFF Can Be Activated in a DNA-bound State
J. Biol. Chem. 2005 280: 6005-6015. First Published on November 30, 2004; doi:10.1074/jbc.M413035200 [Abstract] [Full Text] [PDF]

Setsuko Fujita-Becker, Ulrike Dürrwang, Muriel Erent, Richard J. Clark, Michael A. Geeves, and Dietmar J. Manstein: Changes in Mg²⁺ Ion Concentration and Heavy Chain Phosphorylation Regulate the Motor Activity of a Class I Myosin
J. Biol. Chem. 2005 280: 6064-6071. First Published on December 4, 2004; doi:10.1074/jbc.M412473200 [Abstract] [Full Text] [PDF]

Steven S. Rosenfeld, Anne Houdusse, and H. Lee Sweeney: Magnesium Regulates ADP Dissociation from Myosin V
J. Biol. Chem. 2005 280: 6072-6079. First Published on December 4, 2004; doi:10.1074/jbc.M412717200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Stefanie Storf, Stefan Jansson, and Volkmar H. R. Schmid: Pigment Binding, Fluorescence Properties, and Oligomerization Behavior of Lhca5, a Novel Light-harvesting Protein
J. Biol. Chem. 2005 280: 5163-5168. First Published on November 23, 2004; doi:10.1074/jbc.M411248200 [Abstract] [Full Text] [PDF]

Bryan D. Spiegelberg, June dela Cruz, Tzuo-Hann Law, and John D. York: Alteration of Lithium Pharmacology through Manipulation of Phosphoadenosine Phosphate Metabolism
J. Biol. Chem. 2005 280: 5400-5405. First Published on December 6, 2004; doi:10.1074/jbc.M407890200 [Abstract] [Full Text] [PDF]

Thomas H. Reynolds, IV, Yunbae Pak, Thurl E. Harris, Jill Manchester, Eugene J. Barrett, and John C. Lawrence, Jr.: Effects of Insulin and Transgenic Overexpression of UDP-glucose Pyrophosphorylase on UDP-glucose and Glycogen Accumulation in Skeletal Muscle Fibers
J. Biol. Chem. 2005 280: 5510-5515. First Published on December 13, 2004; doi:10.1074/jbc.M413614200 [Abstract] [Full Text] [PDF]

Antje Waletko, Klaus Zwicker, Albina Abdrakhmanova, Volker Zickermann, Ulrich Brandt, and Stefan Kerscher: Histidine 129 in the 75-kDa Subunit of Mitochondrial Complex I from Yarrowia lipolytica Is Not a Ligand for [Fe₄S₄] Cluster N5 but Is Required for Catalytic Activity
J. Biol. Chem. 2005 280: 5622-5625. First Published on November 30, 2004; doi:10.1074/jbc.M411488200 [Abstract] [Full Text] [PDF]

Koen Brusselmans, Ruth Vrolix, Guido Verhoeven, and Johannes V. Swinnen: Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity
J. Biol. Chem. 2005 280: 5636-5645. First Published on November 8, 2004; doi:10.1074/jbc.M408177200 [Abstract] [Full Text] [PDF]

Yu Shen, Jeong-Il Kim, and Pill-Soon Song: NDPK2 as a Signal Transducer in the Phytochrome-mediated Light Signaling
J. Biol. Chem. 2005 280: 5740-5749. First Published on November 23, 2004; doi:10.1074/jbc.M408965200 [Abstract] [Full Text] [PDF]

Icksoo Lee, Arthur R. Salomon, Scott Ficarro, Isabella Mathes, Friedrich Lottspeich, Lawrence I. Grossman, and Maik Hüttemann: cAMP-dependent Tyrosine Phosphorylation of Subunit I Inhibits Cytochrome c Oxidase Activity
J. Biol. Chem. 2005 280: 6094-6100. First Published on November 19, 2004; doi:10.1074/jbc.M411335200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Kristen R. Taylor, Jennifer A. Rudisill, and Richard L. Gallo: Structural and Sequence Motifs in Dermatan Sulfate for Promoting Fibroblast Growth Factor-2 (FGF-2) and FGF-7 Activity
J. Biol. Chem. 2005 280: 5300-5306. First Published on November 24, 2004; doi:10.1074/jbc.M410412200 [Abstract] [Full Text] [PDF]

Manuel Martinez, Magali Joffraud, Sylvain Giraud, Bénédicte Baïsse, Michael Pierre Bernimoulin, Marc Schapira, and Olivier Spertini: Regulation of PSGL-1 Interactions with L-selectin, P-selectin, and E-selectin: ROLE OF HUMAN FUCOSYLTRANSFERASE-IV AND -VII
J. Biol. Chem. 2005 280: 5378-5390. First Published on December 3, 2004; doi:10.1074/jbc.M410899200 [Abstract] [Full Text] [PDF]

Fiona H. Fenteany and Karen J. Colley: Multiple Signals Are Required for ${alpha}$ 2,6-Sialyltransferase (ST6Gal I) Oligomerization and Golgi Localization
J. Biol. Chem. 2005 280: 5423-5429. First Published on December 6, 2004; doi:10.1074/jbc.M412396200 [Abstract] [Full Text] [PDF]

Nicholas T. Seyfried, Gillian F. McVey, Andrew Almond, David J. Mahoney, Jayesh Dudhia, and Anthony J. Day: Expression and Purification of Functionally Active Hyaluronan-binding Domains from Human Cartilage Link Protein, Aggrecan and Versican: FORMATION OF TERNARY COMPLEXES WITH DEFINED HYALURONAN OLIGOSACCHARIDES
J. Biol. Chem. 2005 280: 5435-5448. First Published on December 8, 2004; doi:10.1074/jbc.M411297200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anne Leppänen, Sean Stowell, Ola Blixt, and Richard D. Cummings: Dimeric Galectin-1 Binds with High Affinity to ${alpha}$ 2,3-Sialylated and Non-sialylated Terminal N-Acetyllactosamine Units on Surface-bound Extended Glycans
J. Biol. Chem. 2005 280: 5549-5562. First Published on November 19, 2004; doi:10.1074/jbc.M412019200 [Abstract] [Full Text] [PDF]

Stefan Berg, James Starbuck, Jordi B. Torrelles, Varalakshmi D. Vissa, Dean C. Crick, Delphi Chatterjee, and Patrick J. Brennan: Roles of Conserved Proline and Glycosyltransferase Motifs of EmbC in Biosynthesis of Lipoarabinomannan
J. Biol. Chem. 2005 280: 5651-5663. First Published on November 16, 2004; doi:10.1074/jbc.M411418200 [Abstract] [Full Text] [PDF]

David Jiménez, Pedro Roda-Navarro, Timothy A. Springer, and José M. Casasnovas: Contribution of N-Linked Glycans to the Conformation and Function of Intercellular Adhesion Molecules (ICAMs)
J. Biol. Chem. 2005 280: 5854-5861. First Published on November 15, 2004; doi:10.1074/jbc.M412104200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Anne Milcamps, Ajay W. Tumaney, Troy Paddock, David A. Pan, John Ohlrogge, and Mike Pollard: Isolation of a Gene Encoding a 1,2-Diacylglycerol-sn-acetyl-CoA Acetyltransferase from Developing Seeds of Euonymus alatus
J. Biol. Chem. 2005 280: 5370-5377. First Published on December 3, 2004; doi:10.1074/jbc.M410276200 [Abstract] [Full Text] [PDF]

Véronique Carrière, Romain Vidal, Kristell Lazou, Michel Lacasa, François Delers, Agnès Ribeiro, Monique Rousset, Jean Chambaz, and Jean Marc Lacorte: HNF-4-dependent Induction of Apolipoprotein A-IV Gene Transcription by an Apical Supply of Lipid Micelles in Intestinal Cells
J. Biol. Chem. 2005 280: 5406-5413. First Published on December 6, 2004; doi:10.1074/jbc.M408002200 [Abstract] [Full Text] [PDF]

Miho Futamura, Padmaja Dhanasekaran, Tetsurou Handa, Michael C. Phillips, Sissel Lund-Katz, and Hiroyuki Saito: Two-step Mechanism of Binding of Apolipoprotein E to Heparin: IMPLICATIONS FOR THE KINETICS OF APOLIPOPROTEIN E-HEPARAN SULFATE PROTEOGLYCAN COMPLEX FORMATION ON CELL SURFACES
J. Biol. Chem. 2005 280: 5414-5422. First Published on December 6, 2004; doi:10.1074/jbc.M411719200 [Abstract] [Full Text] [PDF]

Horst Robenek, Stefan Lorkowski, Michael Schnoor, and David Troyer: Spatial Integration of TIP47 and Adipophilin in Macrophage Lipid Bodies
J. Biol. Chem. 2005 280: 5789-5794. First Published on November 15, 2004; doi:10.1074/jbc.M407194200 [Abstract] [Full Text] [PDF]

Baohai Shao, Constanze Bergt, Xiaoyun Fu, Pattie Green, John C. Voss, Michael N. Oda, John F. Oram, and Jay W. Heinecke: Tyrosine 192 in Apolipoprotein A-I Is the Major Site of Nitration and Chlorination by Myeloperoxidase, but Only Chlorination Markedly Impairs ABCA1-dependent Cholesterol Transport
J. Biol. Chem. 2005 280: 5983-5993. First Published on November 30, 2004; doi:10.1074/jbc.M411484200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Christopher P. Corpe, Je-Hyuk Lee, Oran Kwon, Peter Eck, Jayan Narayanan, Kenneth L. Kirk, and Mark Levine: 6-Bromo-6-deoxy-L-ascorbic Acid: AN ASCORBATE ANALOG SPECIFIC FOR Na⁺-DEPENDENT VITAMIN C TRANSPORTER BUT NOT GLUCOSE TRANSPORTER PATHWAYS
J. Biol. Chem. 2005 280: 5211-5220. First Published on December 6, 2004; doi:10.1074/jbc.M412925200 [Abstract] [Full Text] [PDF]

Allan L. Berger, Christoph O. Randak, Lynda S. Ostedgaard, Philip H. Karp, Daniel W. Vermeer, and Michael J. Welsh: Curcumin Stimulates Cystic Fibrosis Transmembrane Conductance Regulator Cl^– Channel Activity
J. Biol. Chem. 2005 280: 5221-5226. First Published on December 6, 2004; doi:10.1074/jbc.M412972200 [Abstract] [Full Text] [PDF]

Spyros Zissimopoulos and F. Anthony Lai: Interaction of FKBP12.6 with the Cardiac Ryanodine Receptor C-terminal Domain
J. Biol. Chem. 2005 280: 5475-5485. First Published on December 9, 2004; doi:10.1074/jbc.M412954200 [Abstract] [Full Text] [PDF]

Yuki Katanosaka, Yuko Iwata, Yuko Kobayashi, Futoshi Shibasaki, Shigeo Wakabayashi, and Munekazu Shigekawa: Calcineurin Inhibits Na⁺/Ca²⁺ Exchange in Phenylephrine-treated Hypertrophic Cardiomyocytes
J. Biol. Chem. 2005 280: 5764-5772. First Published on November 22, 2004; doi:10.1074/jbc.M410240200 [Abstract] [Full Text] [PDF]

Guangshun Wang, Yifeng Li, and Xia Li: Correlation of Three-dimensional Structures with the Antibacterial Activity of a Group of Peptides Designed Based on a Nontoxic Bacterial Membrane Anchor
J. Biol. Chem. 2005 280: 5803-5811. First Published on November 30, 2004; doi:10.1074/jbc.M410116200 [Abstract] [Full Text] [PDF]

Ganga Krishnamurthy, Rajagopal Vikram, Sudha B. Singh, Nitin Patel, Shruti Agarwal, Gauranga Mukhopadhyay, Sandip K. Basu, and Amitabha Mukhopadhyay: Hemoglobin Receptor in Leishmania Is a Hexokinase Located in the Flagellar Pocket
J. Biol. Chem. 2005 280: 5884-5891. First Published on December 3, 2004; doi:10.1074/jbc.M411845200 [Abstract] [Full Text] [PDF]

Roy Amarilio, Sreekumar Ramachandran, Helena Sabanay, and Sima Lev: Differential Regulation of Endoplasmic Reticulum Structure through VAP-Nir Protein Interaction
J. Biol. Chem. 2005 280: 5934-5944. First Published on November 15, 2004; doi:10.1074/jbc.M409566200 [Abstract] [Full Text] [PDF]

Susana Ravassa, Abdelkader Bennaghmouch, Heidi Kenis, Theo Lindhout, Tilman Hackeng, Jagat Narula, Leo Hofstra, and Chris Reutelingsperger: Annexin A5 Down-regulates Surface Expression of Tissue Factor: A NOVEL MECHANISM OF REGULATING THE MEMBRANE RECEPTOR REPERTOIR
J. Biol. Chem. 2005 280: 6028-6035. First Published on December 2, 2004; doi:10.1074/jbc.M411710200 [Abstract] [Full Text] [PDF]

Lokanatha Valluru, Jian Xu, Yongling Zhu, Sheng Yan, Anis Contractor, and Geoffrey T. Swanson: Ligand Binding Is a Critical Requirement for Plasma Membrane Expression of Heteromeric Kainate Receptors
J. Biol. Chem. 2005 280: 6085-6093. First Published on December 6, 2004; doi:10.1074/jbc.M411549200 [Abstract] [Full Text] [PDF]

Valerie Legendre-Guillemin, Martina Metzler, Jean-Francois Lemaire, Jacynthe Philie, Lu Gan, Michael R. Hayden, and Peter S. McPherson: Huntingtin Interacting Protein 1 (HIP1) Regulates Clathrin Assembly through Direct Binding to the Regulatory Region of the Clathrin Light Chain
J. Biol. Chem. 2005 280: 6101-6108. First Published on November 8, 2004; doi:10.1074/jbc.M408430200 [Abstract] [Full Text] [PDF]

Chih-Ying Chen and Frances M. Brodsky: Huntingtin-interacting Protein 1 (Hip1) and Hip1-related Protein (Hip1R) Bind the Conserved Sequence of Clathrin Light Chains and Thereby Influence Clathrin Assembly in Vitro and Actin Distribution in Vivo
J. Biol. Chem. 2005 280: 6109-6117. First Published on November 8, 2004; doi:10.1074/jbc.M408454200 [Abstract] [Full Text] [PDF]

Baljit S. Khakh and Terrance M. Egan: Contribution of Transmembrane Regions to ATP-gated P2X₂ Channel Permeability Dynamics
J. Biol. Chem. 2005 280: 6118-6129. First Published on November 19, 2004; doi:10.1074/jbc.M411324200 [Abstract] [Full Text] [PDF]

Katrin Brandner, Peter Rehling, and Kaye N. Truscott: The Carboxyl-terminal Third of the Dicarboxylate Carrier Is Crucial for Productive Association with the Inner Membrane Twin-pore Translocase
J. Biol. Chem. 2005 280: 6215-6221. First Published on December 9, 2004; doi:10.1074/jbc.M412269200 [Abstract] [Full Text] [PDF]

Xiao-Qin Ren, Tatsuhiko Furukawa, Yuichi Nakajima, Homare Takahashi, Shunji Aoki, Tomoyuki Sumizawa, Misako Haraguchi, Motomasa Kobayashi, Kazuo Chijiiwa, and Shin-ichi Akiyama: GSH Inhibits Trypsinization of the C-terminal Half of Human MRP1
J. Biol. Chem. 2005 280: 6231-6237. First Published on December 3, 2004; doi:10.1074/jbc.M409498200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Hui Wang, Kyung Song, Tracy L. Sponseller, and David Danielpour: Novel Function of Androgen Receptor-associated Protein 55/Hic-5 as a Negative Regulator of Smad3 Signaling
J. Biol. Chem. 2005 280: 5154-5162. First Published on November 23, 2004; doi:10.1074/jbc.M411575200 [Abstract] [Full Text] [PDF]

Dennis Sohn, Klaus Schulze-Osthoff, and Reiner U. Jänicke: Caspase-8 Can Be Activated by Interchain Proteolysis without Receptor-triggered Dimerization during Drug-induced Apoptosis
J. Biol. Chem. 2005 280: 5267-5273. First Published on December 15, 2004; doi:10.1074/jbc.M408585200 [Abstract] [Full Text] [PDF]

Vidal Fey, Raik Wagner, Katharina Braütigam, Markus Wirtz, Rüdiger Hell, Angela Dietzmann, Dario Leister, Ralf Oelmüller, and Thomas Pfannschmidt: Retrograde Plastid Redox Signals in the Expression of Nuclear Genes for Chloroplast Proteins of Arabidopsis thaliana
J. Biol. Chem. 2005 280: 5318-5328. First Published on November 23, 2004; doi:10.1074/jbc.M406358200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Miri Stolovich, Tal Lerer, Yoav Bolkier, Hannah Cohen, and Oded Meyuhas: Lithium Can Relieve Translational Repression of TOP mRNAs Elicited by Various Blocks along the Cell Cycle in a Glycogen Synthase Kinase-3- and S6-Kinase-independent Manner
J. Biol. Chem. 2005 280: 5336-5342. First Published on November 29, 2004; doi:10.1074/jbc.M412434200 [Abstract] [Full Text] [PDF]

Marina Podestà, Federica Benvenuto, Anna Pitto, Osvaldo Figari, Andrea Bacigalupo, Santina Bruzzone, Lucrezia Guida, Luisa Franco, Laura Paleari, Nicoletta Bodrato, Cesare Usai, Antonio De Flora, and Elena Zocchi: Concentrative Uptake of Cyclic ADP-ribose Generated by BST-1⁺ Stroma Stimulates Proliferation of Human Hematopoietic Progenitors
J. Biol. Chem. 2005 280: 5343-5349. First Published on December 1, 2004; doi:10.1074/jbc.M408085200 [Abstract] [Full Text] [PDF]

Alexandra Montagner, Armelle Yart, Marie Dance, Bertrand Perret, Jean-Pierre Salles, and Patrick Raynal: A Novel Role for Gab1 and SHP2 in Epidermal Growth Factor-induced Ras Activation
J. Biol. Chem. 2005 280: 5350-5360. First Published on December 1, 2004; doi:10.1074/jbc.M410012200 [Abstract] [Full Text] [PDF]

Peili Chen, Mark Levis, Patrick Brown, Kyu-Tae Kim, Jeffrey Allebach, and Donald Small: FLT3/ITD Mutation Signaling Includes Suppression of SHP-1
J. Biol. Chem. 2005 280: 5361-5369. First Published on December 1, 2004; doi:10.1074/jbc.M411974200 [Abstract] [Full Text] [PDF]

Yoshikazu Naiki, Kathrin S. Michelsen, Wenxuang Zhang, Shuang Chen, Terence M. Doherty, and Moshe Arditi: Transforming Growth Factor- ${beta}$ Differentially Inhibits MyD88-dependent, but Not TRAM- and TRIF-dependent, Lipopolysaccharide-induced TLR4 Signaling
J. Biol. Chem. 2005 280: 5491-5495. First Published on December 28, 2004; doi:10.1074/jbc.C400503200 [Abstract] [Full Text] [PDF]

Lihong Yin, Nabila Bennani-Baiti, and C. Thomas Powell: Phorbol Ester-induced Apoptosis of C4-2 Cells Requires Both a Unique and a Redundant Protein Kinase C Signaling Pathway
J. Biol. Chem. 2005 280: 5533-5541. First Published on December 16, 2004; doi:10.1074/jbc.M405266200 [Abstract] [Full Text] [PDF]

Loïc Guillot, Ronan Le Goffic, Sarah Bloch, Nicolas Escriou, Shizuo Akira, Michel Chignard, and Mustapha Si-Tahar: Involvement of Toll-like Receptor 3 in the Immune Response of Lung Epithelial Cells to Double-stranded RNA and Influenza A Virus
J. Biol. Chem. 2005 280: 5571-5580. First Published on December 3, 2004; doi:10.1074/jbc.M410592200 [Abstract] [Full Text] [PDF]

Maya T. Kunkel, Qiang Ni, Roger Y. Tsien, Jin Zhang, and Alexandra C. Newton: Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter
J. Biol. Chem. 2005 280: 5581-5587. First Published on December 6, 2004; doi:10.1074/jbc.M411534200 [Abstract] [Full Text] [PDF] [Summary]

Tanguy Houndolo, Pierre-Luc Boulay, and Audrey Claing: G Protein-coupled Receptor Endocytosis in ADP-ribosylation Factor 6-depleted Cells
J. Biol. Chem. 2005 280: 5598-5604. First Published on December 6, 2004; doi:10.1074/jbc.M411456200 [Abstract] [Full Text] [PDF]

Eugen Brailoiu, Jennifer L. Hoard, Catalin M. Filipeanu, G. Cristina Brailoiu, Siok L. Dun, Sandip Patel, and Nae J. Dun: Nicotinic Acid Adenine Dinucleotide Phosphate Potentiates Neurite Outgrowth
J. Biol. Chem. 2005 280: 5646-5650. First Published on November 4, 2004; doi:10.1074/jbc.M408746200 [Abstract] [Full Text] [PDF]

Bo Li, Nicola M. Nowak, Soo-Kyung Kim, Kenneth A. Jacobson, Ali Bagheri, Clarice Schmidt, and Jürgen Wess: Random Mutagenesis of the M₃ Muscarinic Acetylcholine Receptor Expressed in Yeast: IDENTIFICATION OF SECOND-SITE MUTATIONS THAT RESTORE FUNCTION TO A COUPLING-DEFICIENT MUTANT M₃ RECEPTOR
J. Biol. Chem. 2005 280: 5664-5675. First Published on November 30, 2004; doi:10.1074/jbc.M411623200 [Abstract] [Full Text] [PDF]

M. Cecilia Subauste, Perihan Nalbant, Eileen D. Adamson, and Klaus M. Hahn: Vinculin Controls PTEN Protein Level by Maintaining the Interaction of the Adherens Junction Protein ${beta}$ -Catenin with the Scaffolding Protein MAGI-2
J. Biol. Chem. 2005 280: 5676-5681. First Published on December 5, 2004; doi:10.1074/jbc.M405561200 [Abstract] [Full Text] [PDF]

Seon-Jin Lee, Ki-Mo Kim, Seung Namkoong, Chun-Ki Kim, Yun-Chul Kang, Hansoo Lee, Kwon-Soo Ha, Jeong-A Han, Hun-Taeg Chung, Young-Guen Kwon, and Young-Myeong Kim: Nitric Oxide Inhibition of Homocysteine-induced Human Endothelial Cell Apoptosis by Down-regulation of p53-dependent Noxa Expression through the Formation of S-Nitrosohomocysteine
J. Biol. Chem. 2005 280: 5781-5788. First Published on November 23, 2004; doi:10.1074/jbc.M411224200 [Abstract] [Full Text] [PDF]

Rita Ghosh, Nagalakshmi Nadiminty, James E. Fitzpatrick, William L. Alworth, Thomas J. Slaga, and Addanki P. Kumar: Eugenol Causes Melanoma Growth Suppression through Inhibition of E2F1 Transcriptional Activity
J. Biol. Chem. 2005 280: 5812-5819. First Published on December 1, 2004; doi:10.1074/jbc.M411429200 [Abstract] [Full Text] [PDF]

Stephan J. Kempiak, Hideki Yamaguchi, Corina Sarmiento, Mazen Sidani, Mousumi Ghosh, Robert J. Eddy, Vera DesMarais, Michael Way, John Condeelis, and Jeffrey E. Segall: A Neural Wiskott-Aldrich Syndrome Protein-mediated Pathway for Localized Activation of Actin Polymerization That Is Regulated by Cortactin
J. Biol. Chem. 2005 280: 5836-5842. First Published on December 4, 2004; doi:10.1074/jbc.M410713200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Patrick Nusbaum, Claudianne Lainé, Mohamed Bouaouina, Stéphanie Seveau, Elisabeth M. Cramer, Jean Marc Masse, Philippe Lesavre, and Lise Halbwachs-Mecarelli: Distinct Signaling Pathways Are Involved in Leukosialin (CD43) Down-regulation, Membrane Blebbing, and Phospholipid Scrambling during Neutrophil Apoptosis
J. Biol. Chem. 2005 280: 5843-5853. First Published on December 2, 2004; doi:10.1074/jbc.M413405200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gareth Williams, Emma-Jane Williams, Patrick Maison, Menelas N. Pangalos, Frank S. Walsh, and Patrick Doherty: Overcoming the Inhibitors of Myelin with a Novel Neurotrophin Strategy
J. Biol. Chem. 2005 280: 5862-5869. First Published on November 30, 2004; doi:10.1074/jbc.M411121200 [Abstract] [Full Text] [PDF]

Baskaran Govindarajan, Daniel J. Brat, Marie Csete, William D. Martin, Emma Murad, Karin Litani, Cynthia Cohen, Francesca Cerimele, Matthew Nunnelley, Benjamin Lefkove, Toshiyuki Yamamoto, Chunsik Lee, and Jack L. Arbiser: Transgenic Expression of Dominant Negative Tuberin through a Strong Constitutive Promoter Results in a Tissue-specific Tuberous Sclerosis Phenotype in the Skin and Brain
J. Biol. Chem. 2005 280: 5870-5874. First Published on December 2, 2004; doi:10.1074/jbc.M411768200 [Abstract] [Full Text] [PDF]

David J. Levinthal and Donald B. DeFranco: Reversible Oxidation of ERK-directed Protein Phosphatases Drives Oxidative Toxicity in Neurons
J. Biol. Chem. 2005 280: 5875-5883. First Published on December 3, 2004; doi:10.1074/jbc.M410771200 [Abstract] [Full Text] [PDF]

Micah M. Bhatti and William J. Sullivan, Jr.: Histone Acetylase GCN5 Enters the Nucleus via Importin- ${alpha}$ in Protozoan Parasite Toxoplasma gondii
J. Biol. Chem. 2005 280: 5902-5908. First Published on December 9, 2004; doi:10.1074/jbc.M410656200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jennifer A. Roberts and Malcolm F. White: An Archaeal Endonuclease Displays Key Properties of Both Eukaryal XPF-ERCC1 and Mus81
J. Biol. Chem. 2005 280: 5924-5928. First Published on December 8, 2004; doi:10.1074/jbc.M412766200 [Abstract] [Full Text] [PDF]

Johanna Jyrkkärinne, Björn Windshügel, Janne Mäkinen, Markku Ylisirniö, Mikael Peräkylä, Antti Poso, Wolfgang Sippl, and Paavo Honkakoski: Amino Acids Important for Ligand Specificity of the Human Constitutive Androstane Receptor
J. Biol. Chem. 2005 280: 5960-5971. First Published on November 29, 2004; doi:10.1074/jbc.M411241200 [Abstract] [Full Text] [PDF]

Andreas Till, Philip Rosenstiel, Anja Krippner-Heidenreich, Silvia Mascheretti-Croucher, Peter J. P. Croucher, Heiner Schäfer, Peter Scheurich, Dirk Seegert, and Stefan Schreiber: The Met-196 $->$ Arg Variation of Human Tumor Necrosis Factor Receptor 2 (TNFR2) Affects TNF- ${alpha}$ -induced Apoptosis by Impaired NF- ${kappa}$ B Signaling and Target Gene Expression
J. Biol. Chem. 2005 280: 5994-6004. First Published on November 30, 2004; doi:10.1074/jbc.M411541200 [Abstract] [Full Text] [PDF]

Weijie Li, Christine Marshall, Lijuan Mei, Leonard Dzubow, Chrysalene Schmults, Michael Dans, and John Seykora: Srcasm Modulates EGF and Src-kinase Signaling in Keratinocytes
J. Biol. Chem. 2005 280: 6036-6046. First Published on December 3, 2004; doi:10.1074/jbc.M406546200 [Abstract] [Full Text] [PDF]

Incheol Shin, Jeremy Rotty, Frederick Y. Wu, and Carlos L. Arteaga: Phosphorylation of p27^Kip1 at Thr-157 Interferes with Its Association with Importin ${alpha}$ during G₁ and Prevents Nuclear Re-entry
J. Biol. Chem. 2005 280: 6055-6063. First Published on December 3, 2004; doi:10.1074/jbc.M412367200 [Abstract] [Full Text] [PDF]

Anne-Laure Perraud, Christina L. Takanishi, Betty Shen, Shin Kang, Megan K. Smith, Carsten Schmitz, Heather M. Knowles, Dana Ferraris, Weixing Li, Jie Zhang, Barry L. Stoddard, and Andrew M. Scharenberg: Accumulation of Free ADP-ribose from Mitochondria Mediates Oxidative Stress-induced Gating of TRPM2 Cation Channels
J. Biol. Chem. 2005 280: 6138-6148. First Published on November 23, 2004; doi:10.1074/jbc.M411446200 [Abstract] [Full Text] [PDF]

Bart S. Hendriks, Gayla Orr, Alan Wells, H. Steven Wiley, and Douglas A. Lauffenburger: Parsing ERK Activation Reveals Quantitatively Equivalent Contributions from Epidermal Growth Factor Receptor and HER2 in Human Mammary Epithelial Cells
J. Biol. Chem. 2005 280: 6157-6169. First Published on November 29, 2004; doi:10.1074/jbc.M410491200 [Abstract] [Full Text] [PDF] [Suplemental Data]

Tatiana Syrovets, Jürgen E. Gschwend, Berthold Büchele, Yves Laumonnier, Waltraud Zugmaier, Felicitas Genze, and Thomas Simmet: Inhibition of I ${kappa}$ B Kinase Activity by Acetyl-boswellic Acids Promotes Apoptosis in Androgen-independent PC-3 Prostate Cancer Cells in Vitro and in Vivo
J. Biol. Chem. 2005 280: 6170-6180. First Published on December 2, 2004; doi:10.1074/jbc.M409477200 [Abstract] [Full Text] [PDF]

Maria Alvarado-Kristensson and Tommy Andersson: Protein Phosphatase 2A Regulates Apoptosis in Neutrophils by Dephosphorylating Both p38 MAPK and Its Substrate Caspase 3
J. Biol. Chem. 2005 280: 6238-6244. First Published on November 29, 2004; doi:10.1074/jbc.M409718200 [Abstract] [Full Text] [PDF]

C. David Wood, Ulrica Marklund, and Doreen A. Cantrell: Dual Phospholipase C/Diacylglycerol Requirement for Protein Kinase D1 Activation in Lymphocytes
J. Biol. Chem. 2005 280: 6245-6251. First Published on December 7, 2004; doi:10.1074/jbc.M411564200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Jan Willem Voncken, Hanneke Niessen, Bernd Neufeld, Ulrike Rennefahrt, Vivian Dahlmans, Nard Kubben, Barbara Holzer, Stephan Ludwig, and Ulf R. Rapp: MAPKAP Kinase 3pK Phosphorylates and Regulates Chromatin Association of the Polycomb Group Protein Bmi1
J. Biol. Chem. 2005 280: 5178-5187. First Published on November 24, 2004; doi:10.1074/jbc.M407155200 [Abstract] [Full Text] [PDF]

Sayaka Okumura-Nakanishi, Motoki Saito, Hitoshi Niwa, and Fuyuki Ishikawa: Oct-3/4 and Sox2 Regulate Oct-3/4 Gene in Embryonic Stem Cells
J. Biol. Chem. 2005 280: 5307-5317. First Published on November 22, 2004; doi:10.1074/jbc.M410015200 [Abstract] [Full Text] [PDF]

Nian Huang, Sandeep Negi, Attila Szebeni, and Mark O. J. Olson: Protein NPM3 Interacts with the Multifunctional Nucleolar Protein B23/Nucleophosmin and Inhibits Ribosome Biogenesis
J. Biol. Chem. 2005 280: 5496-5502. First Published on December 13, 2004; doi:10.1074/jbc.M407856200 [Abstract] [Full Text] [PDF]

Manabu Murakami, Takayoshi Ohba, Feng Xu, Seiji Shida, Eisaku Satoh, Kyoichi Ono, Ichiro Miyoshi, Hiroyuki Watanabe, Hiroshi Ito, and Toshihiko Iijima: Genomic Organization and Functional Analysis of Murine PKD2L1
J. Biol. Chem. 2005 280: 5626-5635. First Published on November 17, 2004; doi:10.1074/jbc.M411496200 [Abstract] [Full Text] [PDF]

Ja-Eun Kim, Daniel D. Billadeau, and Junjie Chen: The Tandem BRCT Domains of Ect2 Are Required for Both Negative and Positive Regulation of Ect2 in Cytokinesis
J. Biol. Chem. 2005 280: 5733-5739. First Published on November 15, 2004; doi:10.1074/jbc.M409298200 [Abstract] [Full Text] [PDF]

Warunee Dansithong, Sharan Paul, Lucio Comai, and Sita Reddy: MBNL1 Is the Primary Determinant of Focus Formation and Aberrant Insulin Receptor Splicing in DM1
J. Biol. Chem. 2005 280: 5773-5780. First Published on November 16, 2004; doi:10.1074/jbc.M410781200 [Abstract] [Full Text] [PDF]

Megan J. Wilson, Pancharatnam Jeyasuria, Keith L. Parker, and Peter Koopman: The Transcription Factors Steroidogenic Factor-1 and SOX9 Regulate Expression of Vanin-1 during Mouse Testis Development
J. Biol. Chem. 2005 280: 5917-5923. First Published on December 8, 2004; doi:10.1074/jbc.M412806200 [Abstract] [Full Text] [PDF]

Akio Yamada, Kenji Irie, Takeshi Hirota, Takako Ooshio, Atsunori Fukuhara, and Yoshimi Takai: Involvement of the Annexin II-S100A10 Complex in the Formation of E-cadherin-based Adherens Junctions in Madin-Darby Canine Kidney Cells
J. Biol. Chem. 2005 280: 6016-6027. First Published on December 1, 2004; doi:10.1074/jbc.M408215200 [Abstract] [Full Text] [PDF]

Lee P. Haynes, Geraint M. H. Thomas, and Robert D. Burgoyne: Interaction of Neuronal Calcium Sensor-1 and ADP-ribosylation Factor 1 Allows Bidirectional Control of Phosphatidylinositol 4-Kinase ${beta}$ and trans-Golgi Network-Plasma Membrane Traffic
J. Biol. Chem. 2005 280: 6047-6054. First Published on December 2, 2004; doi:10.1074/jbc.M413090200 [Abstract] [Full Text] [PDF]

Durga Prasad Mishra and Chandrima Shaha: Estrogen-induced Spermatogenic Cell Apoptosis Occurs via the Mitochondrial Pathway: ROLE OF SUPEROXIDE AND NITRIC OXIDE
J. Biol. Chem. 2005 280: 6181-6196. First Published on November 15, 2004; doi:10.1074/jbc.M405970200 [Abstract] [Full Text] [PDF]

Ling Ye, Yuji Mishina, Di Chen, Haiyang Huang, Sarah L. Dallas, Mark R. Dallas, Pitchumani Sivakumar, Tetsuo Kunieda, Takeo W. Tsutsui, Adele Boskey, Lynda F. Bonewald, and Jian Q. Feng: Dmp1-deficient Mice Display Severe Defects in Cartilage Formation Responsible for a Chondrodysplasia-like Phenotype
J. Biol. Chem. 2005 280: 6197-6203. First Published on December 7, 2004; doi:10.1074/jbc.M412911200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Sergej Milovic, Bibiane Steinecker-Frohnwieser, Wolfgang Schreibmayer, and Lukas G. Weigl: The sensitivity of G protein-activated K⁺ channels toward halothane is essentially determined by the C terminus. Vol. 279 (2004) 34240–34249
J. Biol. Chem. 2005 280: 6252. [Full Text] [PDF]