JBC -- Table of Contents (Dec 22 2006, 281, (51))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Protein-tyrosine Phosphatases and PTEN: the Work of Jack E. Dixon
Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate (KL Guan and JE Dixon J. Biol. Chem. 266, 17026-17030)
The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate (Tomohiko Maehama and Jack E. Dixon J. Biol. Chem. 273, 13375-13378)
J. Biol. Chem. 2006 281: e42. [Full Text]

Minireviews:

Sun Hur, Robert M. Stroud, and Janet Finer-Moore: Substrate Recognition by RNA 5-Methyluridine Methyltransferases and Pseudouridine Synthases: A Structural Perspective
J. Biol. Chem. 2006 281: 38969-38973. First Published on November 3, 2006; doi:10.1074/jbc.R600034200 [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Hisao Masai, Chika Taniyama, Keiko Ogino, Etsuko Matsui, Naoko Kakusho, Seiji Matsumoto, Jung-Min Kim, Ai Ishii, Taku Tanaka, Toshiko Kobayashi, Katsuyuki Tamai, Kiyoshi Ohtani, and Ken-ichi Arai: Phosphorylation of MCM4 by Cdc7 Kinase Facilitates Its Interaction with Cdc45 on the Chromatin
J. Biol. Chem. 2006 281: 39249-39261. First Published on October 17, 2006; doi:10.1074/jbc.M608935200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Xinguo Qian, Yujiong He, Xinfeng Ma, Michel N. Fodje, Pawel Grochulski, and Yu Luo: Calcium Stiffens Archaeal Rad51 Recombinase from Methanococcus voltae for Homologous Recombination
J. Biol. Chem. 2006 281: 39380-39387. First Published on October 17, 2006; doi:10.1074/jbc.M607785200 [Abstract] [Full Text] [PDF]

Erin Olson, Christian J. Nievera, Vitaly Klimovich, Ellen Fanning, and Xiaohua Wu: RPA2 Is a Direct Downstream Target for ATR to Regulate the S-phase Checkpoint
J. Biol. Chem. 2006 281: 39517-39533. First Published on October 10, 2006; doi:10.1074/jbc.M605121200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Lezanne Ooi, Nikolai D. Belyaev, Katsuhide Miyake, Ian C. Wood, and Noel J. Buckley: BRG1 Chromatin Remodeling Activity Is Required for Efficient Chromatin Binding by Repressor Element 1-silencing Transcription Factor (REST) and Facilitates REST-mediated Repression
J. Biol. Chem. 2006 281: 38974-38980. First Published on October 4, 2006; doi:10.1074/jbc.M605370200 [Abstract] [Full Text] [PDF]

Ying-Chun Lu, Jun Song, Hee-Yeon Cho, Guoping Fan, Kazunari K. Yokoyama, and Robert Chiu: Cyclophilin A Protects Peg3 from Hypermethylation and Inactive Histone Modification
J. Biol. Chem. 2006 281: 39081-39087. First Published on October 26, 2006; doi:10.1074/jbc.M606687200 [Abstract] [Full Text] [PDF]

Hong Chen, Martin Hewison, and John S. Adams: Functional Characterization of Heterogeneous Nuclear Ribonuclear Protein C1/C2 in Vitamin D Resistance: A NOVEL RESPONSE ELEMENT-BINDING PROTEIN
J. Biol. Chem. 2006 281: 39114-39120. First Published on October 27, 2006; doi:10.1074/jbc.M608006200 [Abstract] [Full Text] [PDF]

Ji Ho Suh, Jiansheng Huang, Yun-Yong Park, Hyun-A Seong, Dongwook Kim, Minho Shong, Hyunjung Ha, In-Kyu Lee, Keesook Lee, Li Wang, and Hueng-Sik Choi: Orphan Nuclear Receptor Small Heterodimer Partner Inhibits Transforming Growth Factor- $beta$ Signaling by Repressing SMAD3 Transactivation
J. Biol. Chem. 2006 281: 39169-39178. First Published on October 30, 2006; doi:10.1074/jbc.M605947200 [Abstract] [Full Text] [PDF]

Kimberly A. Aeling, Michael L. Opel, Nicholas R. Steffen, Vira Tretyachenko-Ladokhina, G. Wesley Hatfield, Richard H. Lathrop, and Donald F. Senear: Indirect Recognition in Sequence-specific DNA Binding by Escherichia coli Integration Host Factor: THE ROLE OF DNA DEFORMATION ENERGY
J. Biol. Chem. 2006 281: 39236-39248. First Published on October 11, 2006; doi:10.1074/jbc.M606363200 [Abstract] [Full Text] [PDF]

Hsuan-Ting Huang, Ondra M. Brand, Matthen Mathew, Christos Ignatiou, Elizabeth P. Ewen, Sarah A. Mccalmon, and Francisco J. Naya: Myomaxin Is a Novel Transcriptional Target of MEF2A That Encodes a Xin-related ${alpha}$ -Actinin-interacting Protein
J. Biol. Chem. 2006 281: 39370-39379. First Published on October 17, 2006; doi:10.1074/jbc.M603244200 [Abstract] [Full Text] [PDF]

Mariam Quinones, Harvey H. Kimsey, Wilma Ross, Richard L. Gourse, and Matthew K. Waldor: LexA Represses CTX ${Phi}$ Transcription by Blocking Access of the ${alpha}$ C-terminal Domain of RNA Polymerase to Promoter DNA
J. Biol. Chem. 2006 281: 39407-39412. First Published on October 17, 2006; doi:10.1074/jbc.M609694200 [Abstract] [Full Text] [PDF]

Tatjana Degenhardt, Merja Matilainen, Karl-Heinz Herzig, Thomas W. Dunlop, and Carsten Carlberg: The Insulin-like Growth Factor-binding Protein 1 Gene Is a Primary Target of Peroxisome Proliferator-activated Receptors
J. Biol. Chem. 2006 281: 39607-39619. First Published on October 24, 2006; doi:10.1074/jbc.M605623200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gang Liu, Lionel C. Clement, Yashpal S. Kanwar, Carmen Avila-Casado, and Sumant S. Chugh: ZHX Proteins Regulate Podocyte Gene Expression during the Development of Nephrotic Syndrome
J. Biol. Chem. 2006 281: 39681-39692. First Published on October 20, 2006; doi:10.1074/jbc.M606664200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Structure, Metabolism, and Catalysis:

Manuela E. Hase, Prakash Yalamanchili, and Neus Visa: The Drosophila Heterogeneous Nuclear Ribonucleoprotein M Protein, HRP59, Regulates Alternative Splicing and Controls the Production of Its Own mRNA
J. Biol. Chem. 2006 281: 39135-39141. First Published on October 31, 2006; doi:10.1074/jbc.M604235200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Omar A. Bazirgan, Renee M. Garza, and Randolph Y. Hampton: Determinants of RING-E2 Fidelity for Hrd1p, a Membrane-anchored Ubiquitin Ligase
J. Biol. Chem. 2006 281: 38989-39001. First Published on October 11, 2006; doi:10.1074/jbc.M608174200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Joon No Lee, Baoliang Song, Russell A. DeBose-Boyd, and Jin Ye: Sterol-regulated Degradation of Insig-1 Mediated by the Membrane-bound Ubiquitin Ligase gp78
J. Biol. Chem. 2006 281: 39308-39315. First Published on October 16, 2006; doi:10.1074/jbc.M608999200 [Abstract] [Full Text] [PDF]

Melaine Delcroix, Mohammed Sajid, Conor R. Caffrey, Kee-C. Lim, Jan Dvorák, Ivy Hsieh, Mahmoud Bahgat, Colette Dissous, and James H. McKerrow: A Multienzyme Network Functions in Intestinal Protein Digestion by a Platyhelminth Parasite
J. Biol. Chem. 2006 281: 39316-39329. First Published on October 6, 2006; doi:10.1074/jbc.M607128200 [Abstract] [Full Text] [PDF]

Matthieu G. Gagnon, Alka Mukhopadhyay, and Sergey V. Steinberg: Close Packing of Helices 3 and 12 of 16 S rRNA Is Required for the Normal Ribosome Function
J. Biol. Chem. 2006 281: 39349-39357. First Published on October 23, 2006; doi:10.1074/jbc.M607725200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genomics, Proteomics, and Bioinformatics:

Winyoo Chowanadisai, Bo Lönnerdal, and Shannon L. Kelleher: Identification of a Mutation in SLC30A2 (ZnT-2) in Women with Low Milk Zinc Concentration That Results in Transient Neonatal Zinc Deficiency
J. Biol. Chem. 2006 281: 39699-39707. First Published on October 25, 2006; doi:10.1074/jbc.M605821200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Salvatore Oddo, Vitaly Vasilevko, Antonella Caccamo, Masashi Kitazawa, David H. Cribbs, and Frank M. LaFerla: Reduction of Soluble A $beta$ and Tau, but Not Soluble A $beta$ Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles
J. Biol. Chem. 2006 281: 39413-39423. First Published on October 20, 2006; doi:10.1074/jbc.M608485200 [Abstract] [Full Text] [PDF]

Harriet E. Seward, Anna Roujeinikova, Kirsty J. McLean, Andrew W. Munro, and David Leys: Crystal Structure of the Mycobacterium tuberculosis P450 CYP121-Fluconazole Complex Reveals New Azole Drug-P450 Binding Mode
J. Biol. Chem. 2006 281: 39437-39443. First Published on October 6, 2006; doi:10.1074/jbc.M607665200 [Abstract] [Full Text] [PDF]

Wen Yuan Chung, Rachel Carter, Tara Hardy, Markus Sack, Timothy R. Hirst, and Roger F. L. James: Inhibition of Escherichia coli Heat-labile Enterotoxin B Subunit Pentamer (EtxB₅) Assembly in Vitro Using Monoclonal Antibodies
J. Biol. Chem. 2006 281: 39465-39470. First Published on October 12, 2006; doi:10.1074/jbc.M606038200 [Abstract] [Full Text] [PDF]

Dhirendra K. Simanshu, Handanahal S. Savithri, and Mathur R. N. Murthy: Crystal Structures of Salmonella typhimurium Biodegradative Threonine Deaminase and Its Complex with CMP Provide Structural Insights into Ligand-induced Oligomerization and Enzyme Activation
J. Biol. Chem. 2006 281: 39630-39641. First Published on October 17, 2006; doi:10.1074/jbc.M605721200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Mathias Antoine, Adeline Gand, Sandrine Boschi-Muller, and Guy Branlant: Characterization of the Amino Acids from Neisseria meningitidis MsrA Involved in the Chemical Catalysis of the Methionine Sulfoxide Reduction Step
J. Biol. Chem. 2006 281: 39062-39070. First Published on October 24, 2006; doi:10.1074/jbc.M608844200 [Abstract] [Full Text] [PDF]

Yue Zhang, Gaoxiang Ge, and Daniel S. Greenspan: Inhibition of Bone Morphogenetic Protein 1 by Native and Altered Forms of ${alpha}$ ₂-Macroglobulin
J. Biol. Chem. 2006 281: 39096-39104. First Published on October 27, 2006; doi:10.1074/jbc.M601362200 [Abstract] [Full Text] [PDF]

Michael A. Bukys, Paul Y. Kim, Michael E. Nesheim, and Michael Kalafatis: A Control Switch for Prothrombinase: CHARACTERIZATION OF A HIRUDIN-LIKE PENTAPEPTIDE FROM THE COOH TERMINUS OF FACTOR Va HEAVY CHAIN THAT REGULATES THE RATE AND PATHWAY FOR PROTHROMBIN ACTIVATION
J. Biol. Chem. 2006 281: 39194-39204. First Published on October 4, 2006; doi:10.1074/jbc.M604482200 [Abstract] [Full Text] [PDF]

Christopher L. Case, Edward M. Concar, Kristin L. Boswell, and Biswarup Mukhopadhyay: Roles of Asp⁷⁵, Asp⁷⁸, and Glu⁸³ of GTP-dependent Phosphoenolpyruvate Carboxykinase from Mycobacterium smegmatis
J. Biol. Chem. 2006 281: 39262-39272. First Published on October 2, 2006; doi:10.1074/jbc.M602591200 [Abstract] [Full Text] [PDF]

Salma Rafi, Polina Novichenok, Subramaniapillai Kolappan, Xujie Zhang, Christopher F. Stratton, Richa Rawat, Caroline Kisker, Carlos Simmerling, and Peter J. Tonge: Structure of Acyl Carrier Protein Bound to FabI, the FASII Enoyl Reductase from Escherichia coli
J. Biol. Chem. 2006 281: 39285-39293. First Published on September 29, 2006; doi:10.1074/jbc.M608758200 [Abstract] [Full Text] [PDF]

Yanli Wang, Lin Liu, Zhiyi Wei, Zhongjun Cheng, Yajing Lin, and Weimin Gong: Seeing the Process of Histidine Phosphorylation in Human Bisphosphoglycerate Mutase
J. Biol. Chem. 2006 281: 39642-39648. First Published on October 18, 2006; doi:10.1074/jbc.M606421200 [Abstract] [Full Text] [PDF]

Neela H. Yennawar, Mohammad Mainul Islam, Myra Conway, Reidar Wallin, and Susan M. Hutson: Human Mitochondrial Branched Chain Aminotransferase Isozyme: STRUCTURAL ROLE OF THE CXXC CENTER IN CATALYSIS
J. Biol. Chem. 2006 281: 39660-39671. First Published on October 18, 2006; doi:10.1074/jbc.M607552200 [Abstract] [Full Text] [PDF]

Marc Bartoli, Nathalie Bourg, Daniel Stockholm, Fabrice Raynaud, Antony Delevacque, Yang Han, Perrine Borel, Kenza Seddik, Nasser Armande, and Isabelle Richard: A Mouse Model for Monitoring Calpain Activity under Physiological and Pathological Conditions
J. Biol. Chem. 2006 281: 39672-39680. First Published on October 20, 2006; doi:10.1074/jbc.M608803200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Marcela Ferella, Andrea Montalvetti, Peter Rohloff, Kildare Miranda, Jianmin Fang, Silvia Reina, Makoto Kawamukai, Jacqueline Búa, Daniel Nilsson, Carlos Pravia, Alejandro Katzin, Maria B. Cassera, Lena Åslund, Björn Andersson, Roberto Docampo, and Esteban J. Bontempi: A Solanesyl-diphosphate Synthase Localizes in Glycosomes of Trypanosoma cruzi
J. Biol. Chem. 2006 281: 39339-39348. First Published on October 24, 2006; doi:10.1074/jbc.M607451200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Lisa R. Warner, Raquel J. Brown, Sorcha M. C. Yingst, and Julia Thom Oxford: Isoform-specific Heparan Sulfate Binding within the Amino-terminal Noncollagenous Domain of Collagen ${alpha}$ 1(XI)
J. Biol. Chem. 2006 281: 39507-39516. First Published on October 24, 2006; doi:10.1074/jbc.M608551200 [Abstract] [Full Text] [PDF]

Annette M. Lechner, Irmgard Assfalg-Machleidt, Stefan Zahler, Mechthild Stoeckelhuber, Werner Machleidt, Marianne Jochum, and Dorit K. Nägler: RGD-dependent Binding of Procathepsin X to Integrin ${alpha}$ _v $beta$ ₃ Mediates Cell-adhesive Properties
J. Biol. Chem. 2006 281: 39588-39597. First Published on October 25, 2006; doi:10.1074/jbc.M513439200 [Abstract] [Full Text] [PDF]

Kerstin Böse, Roswitha Nischt, Anton Page, Bernhard L. Bader, Mats Paulsson, and Neil Smyth: Loss of Nidogen-1 and -2 Results in Syndactyly and Changes in Limb Development
J. Biol. Chem. 2006 281: 39620-39629. First Published on October 5, 2006; doi:10.1074/jbc.M607886200 [Abstract] [Full Text] [PDF]

Susumu Nakahara, Victor Hogan, Hidenori Inohara, and Avraham Raz: Importin-mediated Nuclear Translocation of Galectin-3
J. Biol. Chem. 2006 281: 39649-39659. First Published on October 20, 2006; doi:10.1074/jbc.M608069200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Bénédicte Bakan, Mats Hamberg, Ludivine Perrocheau, Daniel Maume, Hélène Rogniaux, Olivier Tranquet, Corinne Rondeau, Jean-Pierre Blein, Michel Ponchet, and Didier Marion: Specific Adduction of Plant Lipid Transfer Protein by an Allene Oxide Generated by 9-Lipoxygenase and Allene Oxide Synthase
J. Biol. Chem. 2006 281: 38981-38988. First Published on October 16, 2006; doi:10.1074/jbc.M608580200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yang Xu, Ashim Malhotra, Mindong Ren, and Michael Schlame: The Enzymatic Function of Tafazzin
J. Biol. Chem. 2006 281: 39217-39224. First Published on November 2, 2006; doi:10.1074/jbc.M606100200 [Abstract] [Full Text] [PDF]

Vinita Gupta, Vasanthy Narayanaswami, Madhu S. Budamagunta, Taichi Yamamato, John C. Voss, and Robert O. Ryan: Lipid-induced Extension of Apolipoprotein E Helix 4 Correlates with Low Density Lipoprotein Receptor Binding Ability
J. Biol. Chem. 2006 281: 39294-39299. First Published on November 1, 2006; doi:10.1074/jbc.M608085200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Stéphanie Bibert, Sophie Roy, Danièle Schaer, Emanuela Felley-Bosco, and Käthi Geering: Structural and Functional Properties of Two Human FXYD3 (Mat-8) Isoforms
J. Biol. Chem. 2006 281: 39142-39151. First Published on October 31, 2006; doi:10.1074/jbc.M605221200 [Abstract] [Full Text] [PDF]

Ju-Young Lee, Frank Visser, Jae Sung Lee, Kyu-Hee Lee, Jae-Won Soh, Won-Kyung Ho, Jonathan Lytton, and Suk-Ho Lee: Protein Kinase C-dependent Enhancement of Activity of Rat Brain NCKX2 Heterologously Expressed in HEK293 Cells
J. Biol. Chem. 2006 281: 39205-39216. First Published on October 12, 2006; doi:10.1074/jbc.M606287200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Takahiro Hatanaka, Yasue Hatanaka, Jun-ichi Tsuchida, Vadivel Ganapathy, and Mitsutoshi Setou: Amino Acid Transporter ATA2 Is Stored at the trans-Golgi Network and Released by Insulin Stimulus in Adipocytes
J. Biol. Chem. 2006 281: 39273-39284. First Published on October 18, 2006; doi:10.1074/jbc.M604534200 [Abstract] [Full Text] [PDF]

Alexandra Raybaud, Yolaine Dodier, Pierre Bissonnette, Manuel Simoes, Daniel G. Bichet, Rémy Sauvé, and Lucie Parent: The Role of the GX₉GX₃G Motif in the Gating of High Voltage-activated Ca²⁺ Channels
J. Biol. Chem. 2006 281: 39424-39436. First Published on October 11, 2006; doi:10.1074/jbc.M607405200 [Abstract] [Full Text] [PDF]

Arnaud Javelle, Domenico Lupo, Lei Zheng, Xiao-Dan Li, Fritz K. Winkler, and Mike Merrick: An Unusual Twin-His Arrangement in the Pore of Ammonia Channels Is Essential for Substrate Conductance
J. Biol. Chem. 2006 281: 39492-39498. First Published on October 12, 2006; doi:10.1074/jbc.M608325200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Narinobu Juge, Yumi Yoshida, Shouki Yatsushiro, Hiroshi Omote, and Yoshinori Moriyama: Vesicular Glutamate Transporter Contains Two Independent Transport Machineries
J. Biol. Chem. 2006 281: 39499-39506. First Published on October 17, 2006; doi:10.1074/jbc.M607670200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Wiebke Duckwitz, Ralf Hausmann, Armaz Aschrafi, and Günther Schmalzing: P2X₅ Subunit Assembly Requires Scaffolding by the Second Transmembrane Domain and a Conserved Aspartate
J. Biol. Chem. 2006 281: 39561-39572. First Published on September 25, 2006; doi:10.1074/jbc.M606113200 [Abstract] [Full Text] [PDF]

Maier Lorizate, Antonio Cruz, Nerea Huarte, Renate Kunert, Jesús Pérez-Gil, and José L. Nieva: Recognition and Blocking of HIV-1 gp41 Pre-transmembrane Sequence by Monoclonal 4E10 Antibody in a Raft-like Membrane Environment
J. Biol. Chem. 2006 281: 39598-39606. First Published on October 18, 2006; doi:10.1074/jbc.M605998200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Athina Paterou, Pegine Walrad, Paul Craddy, Katelyn Fenn, and Keith Matthews: Identification and Stage-specific Association with the Translational Apparatus of TbZFP3, a CCCH Protein That Promotes Trypanosome Life-cycle Development
J. Biol. Chem. 2006 281: 39002-39013. First Published on October 16, 2006; doi:10.1074/jbc.M604280200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xinrong Fu, Yuk-Kwan Choi, Dianbo Qu, Yan Yu, Nam Sang Cheung, and Robert Z. Qi: Identification of Nuclear Import Mechanisms for the Neuronal Cdk5 Activator
J. Biol. Chem. 2006 281: 39014-39021. First Published on October 23, 2006; doi:10.1074/jbc.M512663200 [Abstract] [Full Text] [PDF] [Supplemental Data]

John J. Jennings, Jr., Jian-hui Zhu, Youssef Rbaibi, Xiang Luo, Charleen T. Chu, and Kirill Kiselyov: Mitochondrial Aberrations in Mucolipidosis Type IV
J. Biol. Chem. 2006 281: 39041-39050. First Published on October 20, 2006; doi:10.1074/jbc.M607982200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Troy C. Krzysiak and Susan P. Gilbert: Dimeric Eg5 Maintains Processivity through Alternating-site Catalysis with Rate-limiting ATP Hydrolysis
J. Biol. Chem. 2006 281: 39444-39454. First Published on October 23, 2006; doi:10.1074/jbc.M608056200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kris A. DeMali, April L. Jue, and Keith Burridge: IpaA Targets $beta$ 1 Integrins and Rho to Promote Actin Cytoskeleton Rearrangements Necessary for Shigella Entry
J. Biol. Chem. 2006 281: 39534-39541. First Published on October 22, 2006; doi:10.1074/jbc.M605939200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Olga Vagin, Elmira Tokhtaeva, and George Sachs: The Role of the $beta$ ₁ Subunit of the Na,K-ATPase and Its Glycosylation in Cell-Cell Adhesion
J. Biol. Chem. 2006 281: 39573-39587. First Published on October 19, 2006; doi:10.1074/jbc.M606507200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Jin Ding, Xinhai Zhang, Jingxia Li, Lun Song, Weiming Ouyang, Dongyun Zhang, Caifang Xue, Max Costa, J. Andrés Meléndez, and Chuanshu Huang: Nickel Compounds Render Anti-apoptotic Effect to Human Bronchial Epithelial Beas-2B Cells by Induction of Cyclooxygenase-2 through an IKK $beta$ /p65-dependent and IKK ${alpha}$ - and p50-independent Pathway
J. Biol. Chem. 2006 281: 39022-39032. First Published on September 18, 2006; doi:10.1074/jbc.M604798200 [Abstract] [Full Text] [PDF]

Yijun Jin, Emily K. Blue, and Patricia J. Gallagher: Control of Death-associated Protein Kinase (DAPK) Activity by Phosphorylation and Proteasomal Degradation
J. Biol. Chem. 2006 281: 39033-39040. First Published on October 20, 2006; doi:10.1074/jbc.M605097200 [Abstract] [Full Text] [PDF]

Young Sun Kim, Kyung-Ok Cho, Hong Joon Lee, Seong Yun Kim, Yasufumi Sato, and Young-Jin Cho: Down Syndrome Candidate Region 1 Increases the Stability of the I ${kappa}$ B ${alpha}$ Protein: IMPLICATIONS FOR ITS ANTI-INFLAMMATORY EFFECTS
J. Biol. Chem. 2006 281: 39051-39061. First Published on October 24, 2006; doi:10.1074/jbc.M604659200 [Abstract] [Full Text] [PDF]

Rachel Zhande, Wenshuo Zhang, Yanbin Zheng, Elisha Pendleton, Yu Li, Roberto D. Polakiewicz, and Xiao Jian Sun: Dephosphorylation by Default, a Potential Mechanism for Regulation of Insulin Receptor Substrate-1/2, Akt, and ERK1/2
J. Biol. Chem. 2006 281: 39071-39080. First Published on October 26, 2006; doi:10.1074/jbc.M605251200 [Abstract] [Full Text] [PDF]

Kay Johswich, Myriam Martin, Jessica Thalmann, Claudia Rheinheimer, Peter N. Monk, and Andreas Klos: Ligand Specificity of the Anaphylatoxin C5L2 Receptor and Its Regulation on Myeloid and Epithelial Cell Lines
J. Biol. Chem. 2006 281: 39088-39095. First Published on October 26, 2006; doi:10.1074/jbc.M609734200 [Abstract] [Full Text] [PDF]

Amitava Das, Martin E. Fernandez-Zapico, Sheng Cao, Janet Yao, Stefano Fiorucci, Robert P. Hebbel, Raul Urrutia, and Vijay H. Shah: Disruption of an SP2/KLF6 Repression Complex by SHP Is Required for Farnesoid X Receptor-induced Endothelial Cell Migration
J. Biol. Chem. 2006 281: 39105-39113. First Published on October 27, 2006; doi:10.1074/jbc.M607720200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Olof Idevall Hagren and Anders Tengholm: Glucose and Insulin Synergistically Activate Phosphatidylinositol 3-Kinase to Trigger Oscillations of Phosphatidylinositol 3,4,5-Trisphosphate in $beta$ -Cells
J. Biol. Chem. 2006 281: 39121-39127. First Published on October 30, 2006; doi:10.1074/jbc.M607445200 [Abstract] [Full Text] [PDF]

Hongmei Wang, Neil Kubica, Leif W. Ellisen, Leonard S. Jefferson, and Scot R. Kimball: Dexamethasone Represses Signaling through the Mammalian Target of Rapamycin in Muscle Cells by Enhancing Expression of REDD1
J. Biol. Chem. 2006 281: 39128-39134. First Published on October 30, 2006; doi:10.1074/jbc.M610023200 [Abstract] [Full Text] [PDF]

Johan Lennartsson, Piotr Wardega, Ulla Engström, Ulf Hellman, and Carl-Henrik Heldin: Alix Facilitates the Interaction between c-Cbl and Platelet-derived Growth Factor $beta$ -Receptor and Thereby Modulates Receptor Down-regulation
J. Biol. Chem. 2006 281: 39152-39158. First Published on November 2, 2006; doi:10.1074/jbc.M608489200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jian Zhang, Fuyang Li, Xinping Liu, Lan Shen, Junye Liu, Jin Su, Wei Zhang, Yanchun Deng, Lifeng Wang, Na Liu, Wei Han, Jing Zhang, Shaoping Ji, Angang Yang, Hua Han, and Libo Yao: The Repression of Human Differentiation-related Gene NDRG2 Expression by Myc via Miz-1-dependent Interaction with the NDRG2 Core Promoter
J. Biol. Chem. 2006 281: 39159-39168. First Published on October 18, 2006; doi:10.1074/jbc.M605820200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Qigui Yu, Edith M. C. Chow, Henry Wong, Jenny Gu, Ofer Mandelboim, Scott D. Gray-Owen, and Mario A. Ostrowski: CEACAM1 (CD66a) Promotes Human Monocyte Survival via a Phosphatidylinositol 3-Kinase- and AKT-dependent Pathway
J. Biol. Chem. 2006 281: 39179-39193. First Published on October 27, 2006; doi:10.1074/jbc.M608864200 [Abstract] [Full Text] [PDF]

Inbal Ziv, Yaron Fuchs, Ella Preger, Ariel Shabtay, Haggar Harduf, Tal Zilpa, Naama Dym, and Dina Ron: The Human Sef-a Isoform Utilizes Different Mechanisms to Regulate Receptor Tyrosine Kinase Signaling Pathways and Subsequent Cell Fate
J. Biol. Chem. 2006 281: 39225-39235. First Published on October 10, 2006; doi:10.1074/jbc.M607327200 [Abstract] [Full Text] [PDF]

Gonzalo E. Yevenes, Gustavo Moraga-Cid, Leonardo Guzmán, Svenja Haeger, Laerte Oliveira, Juan Olate, Günther Schmalzing, and Luis G. Aguayo: Molecular Determinants for G Protein $beta$ ${gamma}$ Modulation of Ionotropic Glycine Receptors
J. Biol. Chem. 2006 281: 39300-39307. First Published on October 12, 2006; doi:10.1074/jbc.M608272200 [Abstract] [Full Text] [PDF]

Fiona A. Lee, Marjolijn van Lier, Ingrid A. M. Relou, Loraine Foley, Jan-Willem N. Akkerman, Harry F. G. Heijnen, and Richard W. Farndale: Lipid Rafts Facilitate the Interaction of PECAM-1 with the Glycoprotein VI-FcR ${gamma}$ -Chain Complex in Human Platelets
J. Biol. Chem. 2006 281: 39330-39338. First Published on October 26, 2006; doi:10.1074/jbc.M607930200 [Abstract] [Full Text] [PDF]

Caroline M. McKinnon, Magalie A. Ravier, and Guy A. Rutter: FoxO1 Is Required for the Regulation of Preproglucagon Gene Expression by Insulin in Pancreatic ${alpha}$ TC1-9 Cells
J. Biol. Chem. 2006 281: 39358-39369. First Published on October 24, 2006; doi:10.1074/jbc.M605022200 [Abstract] [Full Text] [PDF]

Sang Woon Shin, Guowu Bian, and Alexander S. Raikhel: A Toll Receptor and a Cytokine, Toll5A and Spz1C, Are Involved in Toll Antifungal Immune Signaling in the Mosquito Aedes aegypti
J. Biol. Chem. 2006 281: 39388-39395. First Published on October 26, 2006; doi:10.1074/jbc.M608912200 [Abstract] [Full Text] [PDF]

Robert V. Stahelin, Dimitrios Karathanassis, Karol S. Bruzik, Michael D. Waterfield, Jerónimo Bravo, Roger L. Williams, and Wonhwa Cho: Structural and Membrane Binding Analysis of the Phox Homology Domain of Phosphoinositide 3-Kinase-C2 ${alpha}$
J. Biol. Chem. 2006 281: 39396-39406. First Published on October 12, 2006; doi:10.1074/jbc.M607079200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Melissa Rasar, Donald B. DeFranco, and Stephen R. Hammes: Paxillin Regulates Steroid-triggered Meiotic Resumption in Oocytes by Enhancing an All-or-None Positive Feedback Kinase Loop
J. Biol. Chem. 2006 281: 39455-39464. First Published on October 25, 2006; doi:10.1074/jbc.M608959200 [Abstract] [Full Text] [PDF]

Simon R. Tew and Timothy E. Hardingham: Regulation of SOX9 mRNA in Human Articular Chondrocytes Involving p38 MAPK Activation and mRNA Stabilization
J. Biol. Chem. 2006 281: 39471-39479. First Published on October 18, 2006; doi:10.1074/jbc.M604322200 [Abstract] [Full Text] [PDF]

Sami Sarfaraz, Farrukh Afaq, Vaqar M. Adhami, Arshi Malik, and Hasan Mukhtar: Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G₁ Cell Cycle Arrest
J. Biol. Chem. 2006 281: 39480-39491. First Published on October 26, 2006; doi:10.1074/jbc.M603495200 [Abstract] [Full Text] [PDF]

Wenfu Tan, Daniel Martin, and J. Silvio Gutkind: The G ${alpha}$ ₁₃-Rho Signaling Axis Is Required for SDF-1-induced Migration through CXCR4
J. Biol. Chem. 2006 281: 39542-39549. First Published on October 20, 2006; doi:10.1074/jbc.M609062200 [Abstract] [Full Text] [PDF]

Venugopalan D. Nair, Kevin St. P. McNaught, Javier González-Maeso, Stuart C. Sealfon, and C. Warren Olanow: p53 Mediates Nontranscriptional Cell Death in Dopaminergic Cells in Response to Proteasome Inhibition
J. Biol. Chem. 2006 281: 39550-39560. First Published on October 23, 2006; doi:10.1074/jbc.M603950200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sadaf-Ahmahni Hussain, Michael Piper, Noémi Fukuhara, Laure Strochlic, Gian Cho, Jason A. Howitt, Yassir Ahmed, Andrew K. Powell, Jeremy E. Turnbull, Christine E. Holt, and Erhard Hohenester: A Molecular Mechanism for the Heparan Sulfate Dependence of Slit-Robo Signaling
J. Biol. Chem. 2006 281: 39693-39698. First Published on October 24, 2006; doi:10.1074/jbc.M609384200 [Abstract] [Full Text] [PDF]

Ryan E. Hibbs, Zoran Radic, Palmer Taylor, and David A. Johnson: Influence of Agonists and Antagonists on the Segmental Motion of Residues near the Agonist Binding Pocket of the Acetylcholine-binding Protein
J. Biol. Chem. 2006 281: 39708-39718. First Published on October 26, 2006; doi:10.1074/jbc.M604752200 [Abstract] [Full Text] [PDF]

Craig A. Eyster, Quwanza S. Duggins, Gary J. Gorbsky, and Ann Louise Olson: Microtubule Network Is Required for Insulin Signaling through Activation of Akt/Protein Kinase B: EVIDENCE THAT INSULIN STIMULATES VESICLE DOCKING/FUSION BUT NOT INTRACELLULAR MOBILITY
J. Biol. Chem. 2006 281: 39719-39727. First Published on October 26, 2006; doi:10.1074/jbc.M607101200 [Abstract] [Full Text] [PDF] [Supplemental Data]

John M. Taylor, Douglas Quilty, Logan Banadyga, and Michele Barry: The Vaccinia Virus Protein F1L Interacts with Bim and Inhibits Activation of the Pro-apoptotic Protein Bax
J. Biol. Chem. 2006 281: 39728-39739. First Published on October 30, 2006; doi:10.1074/jbc.M607465200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Marie E. Fraser, Masao Fujinaga, Maia M. Cherney, Angela R. Melton-Celsa, Edda M. Twiddy, Alison D. O'Brien, and Michael N. G. James: Structure of Shiga toxin type 2 (Stx2) from Escherichia coli O157:H7. VOLUME 279 (2004) PAGES 27511-27517
J. Biol. Chem. 2006 281: 39740. [Full Text] [PDF]

Nancy López-Antón, Anita Rudy, Nicole Barth, M. Lienhard Schmitz, George R. Pettit, Klaus Schulze-Osthoff, Verena M. Dirsch, and Angelika M. Vollmar: The marine product cephalostatin 1 activates an endoplasmic reticulum stress-specific and apoptosomeindependent apoptotic signaling pathway. VOLUME 281 (2006) PAGES 33078-33086
J. Biol. Chem. 2006 281: 39740-a. [Full Text] [PDF]