JBC -- Table of Contents (Feb 10 2006, 281, (6))

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Judith P. Klinman: The Copper-Enzyme Family of Dopamine $beta$ -Monooxygenase and Peptidylglycine ${alpha}$ -Hydroxylating Monooxygenase: Resolving the Chemical Pathway for Substrate Hydroxylation
J. Biol. Chem. 2006 281: 3013-3016. First Published on November 21, 2005; doi:10.1074/jbc.R500011200 [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Tomasz Kulikowicz and Theresa A. Shapiro: Distinct Genes Encode Type II Topoisomerases for the Nucleus and Mitochondrion in the Protozoan Parasite Trypanosoma brucei
J. Biol. Chem. 2006 281: 3048-3056. First Published on November 28, 2005; doi:10.1074/jbc.M505977200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Eleni S. Stanitsa, Lisa Arps, and Paula Traktman: Vaccinia Virus Uracil DNA Glycosylase Interacts with the A20 Protein to Form a Heterodimeric Processivity Factor for the Viral DNA Polymerase
J. Biol. Chem. 2006 281: 3439-3451. First Published on December 1, 2005; doi:10.1074/jbc.M511239200 [Abstract] [Full Text] [PDF]

Taku Tanaka and Hisao Masai: Stabilization of a Stalled Replication Fork by Concerted Actions of Two Helicases
J. Biol. Chem. 2006 281: 3484-3493. First Published on December 13, 2005; doi:10.1074/jbc.M510979200 [Abstract] [Full Text] [PDF]

Samuel G. Mackintosh, Jeff Zhiqiang Lu, John B. Jordan, Melody K. Harrison, Bartek Sikora, Suresh D. Sharma, Craig E. Cameron, Kevin D. Raney, and Joshua Sakon: Structural and Biological Identification of Residues on the Surface of NS3 Helicase Required for Optimal Replication of the Hepatitis C Virus
J. Biol. Chem. 2006 281: 3528-3535. First Published on November 22, 2005; doi:10.1074/jbc.M512100200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Anja Krones-Herzig, Andrea Mesaros, Dagmar Metzger, Anja Ziegler, Ulrike Lemke, Jens C. Brüning, and Stephan Herzig: Signal-dependent Control of Gluconeogenic Key Enzyme Genes through Coactivator-associated Arginine Methyltransferase 1
J. Biol. Chem. 2006 281: 3025-3029. First Published on December 5, 2005; doi:10.1074/jbc.M509770200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Dennis J. Chia, Mitsuru Ono, Joachim Woelfle, Mylynda Schlesinger-Massart, Honglin Jiang, and Peter Rotwein: Characterization of Distinct Stat5b Binding Sites That Mediate Growth Hormone-stimulated IGF-I Gene Transcription
J. Biol. Chem. 2006 281: 3190-3197. First Published on December 7, 2005; doi:10.1074/jbc.M510204200 [Abstract] [Full Text] [PDF]

Sonali Das, Simone V. Ward, Robert S. Tacke, Guntrum Suske, and Charles E. Samuel: Activation of the RNA-dependent Protein Kinase PKR Promoter in the Absence of Interferon Is Dependent Upon Sp Proteins
J. Biol. Chem. 2006 281: 3244-3253. First Published on December 8, 2005; doi:10.1074/jbc.M510612200 [Abstract] [Full Text] [PDF]

Catherine K. Yang, Jeong Hoon Kim, Hongwei Li, and Michael R. Stallcup: Differential Use of Functional Domains by Coiled-coil Coactivator in Its Synergistic Coactivator Function with $beta$ -Catenin or GRIP1
J. Biol. Chem. 2006 281: 3389-3397. First Published on December 12, 2005; doi:10.1074/jbc.M510403200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Structure, Metabolism, and Catalysis:

Shuhua Ma, Tracey Musa, and Jnanankur Bag: Reduced Stability of Mitogen-activated Protein Kinase Kinase-2 mRNA and Phosphorylation of Poly(A)-binding Protein (PABP) in Cells Overexpressing PABP
J. Biol. Chem. 2006 281: 3145-3156. First Published on December 6, 2005; doi:10.1074/jbc.M508937200 [Abstract] [Full Text] [PDF]

Anne-Laure Todeschini, Ciarán Condon, and Lionel Bénard: Sodium-induced GCN4 Expression Controls the Accumulation of the 5' to 3' RNA Degradation Inhibitor, 3'-Phosphoadenosine 5'-Phosphate
J. Biol. Chem. 2006 281: 3276-3282. First Published on December 13, 2005; doi:10.1074/jbc.M511688200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Yu-shin Sou, Isei Tanida, Masaaki Komatsu, Takashi Ueno, and Eiki Kominami: Phosphatidylserine in Addition to Phosphatidylethanolamine Is an in Vitro Target of the Mammalian Atg8 Modifiers, LC3, GABARAP, and GATE-16
J. Biol. Chem. 2006 281: 3017-3024. First Published on November 22, 2005; doi:10.1074/jbc.M505888200 [Abstract] [Full Text] [PDF]

Ayman S. El-Guindy, So Yeon Paek, Jill Countryman, and George Miller: Identification of Constitutive Phosphorylation Sites on the Epstein-Barr Virus ZEBRA Protein
J. Biol. Chem. 2006 281: 3085-3095. First Published on December 1, 2005; doi:10.1074/jbc.M506076200 [Abstract] [Full Text] [PDF]

Jongrak Kittiworakarn, Alain Lecoq, Gervaise Moine, Robert Thai, Evelyne Lajeunesse, Pascal Drevet, Claude Vidaud, André Ménez, and Michel Léonetti: HIV-1 Tat Raises an Adjuvant-free Humoral Immune Response Controlled by Its Core Region and Its Ability to Form Cysteine-mediated Oligomers
J. Biol. Chem. 2006 281: 3105-3115. First Published on December 1, 2005; doi:10.1074/jbc.M509899200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nina L. Tsakadze, Srinivas D. Sithu, Utpal Sen, William R. English, Gillian Murphy, and Stanley E. D'Souza: Tumor Necrosis Factor- ${alpha}$ -converting Enzyme (TACE/ADAM-17) Mediates the Ectodomain Cleavage of Intercellular Adhesion Molecule-1 (ICAM-1)
J. Biol. Chem. 2006 281: 3157-3164. First Published on December 6, 2005; doi:10.1074/jbc.M510797200 [Abstract] [Full Text] [PDF]

Noriyuki Matsuda, Toshiaki Kitami, Toshiaki Suzuki, Yoshikuni Mizuno, Nobutaka Hattori, and Keiji Tanaka: Diverse Effects of Pathogenic Mutations of Parkin That Catalyze Multiple Monoubiquitylation in Vitro
J. Biol. Chem. 2006 281: 3204-3209. First Published on December 8, 2005; doi:10.1074/jbc.M510393200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sang-Nam Lee, Jae Ryoung Hwang, and Iris Lindberg: Neuroendocrine Protein 7B2 Can Be Inactivated by Phosphorylation within the Secretory Pathway
J. Biol. Chem. 2006 281: 3312-3320. First Published on November 14, 2005; doi:10.1074/jbc.M506635200 [Abstract] [Full Text] [PDF]

Asta Jurkuvenaite, Karoly Varga, Krzysztof Nowotarski, Kevin L. Kirk, Eric J. Sorscher, Yao Li, John P. Clancy, Zsuzsa Bebok, and James F. Collawn: Mutations in the Amino Terminus of the Cystic Fibrosis Transmembrane Conductance Regulator Enhance Endocytosis
J. Biol. Chem. 2006 281: 3329-3334. First Published on December 8, 2005; doi:10.1074/jbc.M508131200 [Abstract] [Full Text] [PDF]

Diane E. Handy, Gaozhen Hang, John Scolaro, Nicole Metes, Nadia Razaq, Yi Yang, and Joseph Loscalzo: Aminoglycosides Decrease Glutathione Peroxidase-1 Activity by Interfering with Selenocysteine Incorporation
J. Biol. Chem. 2006 281: 3382-3388. First Published on December 14, 2005; doi:10.1074/jbc.M511295200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Martina Sanderson-Smith, Michael Batzloff, Kabada S. Sriprakash, Mark Dowton, Marie Ranson, and Mark J. Walker: Divergence in the Plasminogen-binding Group A Streptococcal M Protein Family: FUNCTIONAL CONSERVATION OF BINDING SITE AND POTENTIAL ROLE FOR IMMUNE SELECTION OF VARIANTS
J. Biol. Chem. 2006 281: 3217-3226. First Published on November 30, 2005; doi:10.1074/jbc.M508758200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Sirik Rutger Leliveld, Remus Thei Dame, Gijs J. L. Wuite, Lothar Stitz, and Carsten Korth: The Expanded Octarepeat Domain Selectively Binds Prions and Disrupts Homomeric Prion Protein Interactions
J. Biol. Chem. 2006 281: 3268-3275. First Published on December 13, 2005; doi:10.1074/jbc.M510606200 [Abstract] [Full Text] [PDF]

Takaki Koide, Shinichi Asada, Yoshifumi Takahara, Yoshimi Nishikawa, Kazuhiro Nagata, and Kouki Kitagawa: Specific Recognition of the Collagen Triple Helix by Chaperone HSP47: MINIMAL STRUCTURAL REQUIREMENT AND SPATIAL MOLECULAR ORIENTATION
J. Biol. Chem. 2006 281: 3432-3438. First Published on December 2, 2005; doi:10.1074/jbc.M509707200 [Abstract] [Full Text] [PDF]

Choong-Hwan Lee, Hyun Jin Kim, Jung-Ho Lee, Hyun-Ju Cho, Jongsun Kim, Kwang Chul Chung, Seunho Jung, and Seung R. Paik: Dequalinium-induced Protofibril Formation of ${alpha}$ -Synuclein
J. Biol. Chem. 2006 281: 3463-3472. First Published on December 5, 2005; doi:10.1074/jbc.M505307200 [Abstract] [Full Text] [PDF]

Andrew D. Ferguson, Vyacheslav M. Labunskyy, Dmitri E. Fomenko, Demet Araç, Yogarany Chelliah, Carlos A. Amezcua, Josep Rizo, Vadim N. Gladyshev, and Johann Deisenhofer: NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family
J. Biol. Chem. 2006 281: 3536-3543. First Published on November 30, 2005; doi:10.1074/jbc.M511386200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Galina I. Lepesheva, Natalia G. Zaitseva, W. David Nes, Wenxu Zhou, Miharu Arase, Jialin Liu, George C. Hill, and Michael R. Waterman: CYP51 from Trypanosoma cruzi: A PHYLA-SPECIFIC RESIDUE IN THE B' HELIX DEFINES SUBSTRATE PREFERENCES OF STEROL 14 ${alpha}$ -DEMETHYLASE
J. Biol. Chem. 2006 281: 3577-3585. First Published on November 30, 2005; doi:10.1074/jbc.M510317200 [Abstract] [Full Text] [PDF] [Supplmental Data]

James A. Letts, Natisha L. Rose, Ying R. Fang, Christopher H. Barry, Svetlana N. Borisova, Nina O. L. Seto, Monica M. Palcic, and Stephen V. Evans: Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases
J. Biol. Chem. 2006 281: 3625-3632. First Published on December 2, 2005; doi:10.1074/jbc.M507620200 [Abstract] [Full Text] [PDF]

Kenji Ogura, Ikuo Nobuhisa, Satoru Yuzawa, Ryu Takeya, Shinnosuke Torikai, Kazuya Saikawa, Hideki Sumimoto, and Fuyuhiko Inagaki: NMR Solution Structure of the Tandem Src Homology 3 Domains of p47^phox Complexed with a p22^phox-derived Proline-rich Peptide
J. Biol. Chem. 2006 281: 3660-3668. First Published on December 2, 2005; doi:10.1074/jbc.M505193200 [Abstract] [Full Text] [PDF]

Huw T. Jenkins, Linda Mark, Graeme Ball, Jenny Persson, Gunnar Lindahl, Dusan Uhrin, Anna M. Blom, and Paul N. Barlow: Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
J. Biol. Chem. 2006 281: 3690-3697. First Published on December 5, 2005; doi:10.1074/jbc.M511563200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Junko Takeshita, Jaeman Byun, Thomas Q. Nhan, David K. Pritchard, Subramaniam Pennathur, Steven M. Schwartz, Alan Chait, and Jay W. Heinecke: Myeloperoxidase Generates 5-Chlorouracil in Human Atherosclerotic Tissue: A POTENTIAL PATHWAY FOR SOMATIC MUTAGENESIS BY MACROPHAGES
J. Biol. Chem. 2006 281: 3096-3104. First Published on December 1, 2005; doi:10.1074/jbc.M509236200 [Abstract] [Full Text] [PDF]

Pedro Francisco Angelo, Aurelio Resende Lima, Fabiana M. Alves, Sachiko I. Blaber, Isobel A. Scarisbrick, Michael Blaber, Luiz Juliano, and Maria Aparecida Juliano: Substrate Specificity of Human Kallikrein 6: SALT AND GLYCOSAMINOGLYCAN ACTIVATION EFFECTS
J. Biol. Chem. 2006 281: 3116-3126. First Published on December 1, 2005; doi:10.1074/jbc.M510096200 [Abstract] [Full Text] [PDF]

Shih-Long Tu, Wesley Sughrue, R. David Britt, and J. Clark Lagarias: A Conserved Histidine-Aspartate Pair Is Required for Exovinyl Reduction of Biliverdin by a Cyanobacterial Phycocyanobilin:Ferredoxin Oxidoreductase
J. Biol. Chem. 2006 281: 3127-3136. First Published on December 2, 2005; doi:10.1074/jbc.M510126200 [Abstract] [Full Text] [PDF]

Chih-Yu Cheng, Chu-Han Chang, Yue-Jin Wu, and Yaw-Kuen Li: Exploration of Glycosyl Hydrolase Family 75, a Chitosanase from Aspergillus fumigatus
J. Biol. Chem. 2006 281: 3137-3144. First Published on December 5, 2005; doi:10.1074/jbc.M512506200 [Abstract] [Full Text] [PDF]

Jun Hirao, Shingo Arakawa, Kyoko Watanabe, Kazumi Ito, and Tadashi Furukawa: Effects of Restricted Feeding on Daily Fluctuations of Hepatic Functions Including P450 Monooxygenase Activities in Rats
J. Biol. Chem. 2006 281: 3165-3171. First Published on December 6, 2005; doi:10.1074/jbc.M511194200 [Abstract] [Full Text] [PDF]

I-Chueh Huang, Berend Jan Bosch, Fang Li, Wenhui Li, Kyoung Hoa Lee, Sorina Ghiran, Natalya Vasilieva, Terence S. Dermody, Stephen C. Harrison, Philip R. Dormitzer, Michael Farzan, Peter J. M. Rottier, and Hyeryun Choe: SARS Coronavirus, but Not Human Coronavirus NL63, Utilizes Cathepsin L to Infect ACE2-expressing Cells
J. Biol. Chem. 2006 281: 3198-3203. First Published on December 8, 2005; doi:10.1074/jbc.M508381200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Brendan P. Eckelman and Guy S. Salvesen: The Human Anti-apoptotic Proteins cIAP1 and cIAP2 Bind but Do Not Inhibit Caspases
J. Biol. Chem. 2006 281: 3254-3260. First Published on December 8, 2005; doi:10.1074/jbc.M510863200 [Abstract] [Full Text] [PDF]

David J. McGee, Sateesh Kumar, Ryan J. Viator, Jeffrey R. Bolland, Julio Ruiz, Domenico Spadafora, Traci L. Testerman, David J. Kelly, Lewis K. Pannell, and Henry J. Windle: Helicobacter pylori Thioredoxin Is an Arginase Chaperone and Guardian against Oxidative and Nitrosative Stresses
J. Biol. Chem. 2006 281: 3290-3296. First Published on December 14, 2005; doi:10.1074/jbc.M506139200 [Abstract] [Full Text] [PDF]

Katrin Dassler, Martin Zydek, Krzysztof Wandzik, Matthias Kaup, and Hendrik Fuchs: Release of the Soluble Transferrin Receptor Is Directly Regulated by Binding of Its Ligand Ferritransferrin
J. Biol. Chem. 2006 281: 3297-3304. First Published on December 14, 2005; doi:10.1074/jbc.M511341200 [Abstract] [Full Text] [PDF]

Alexey Dementiev, József Dobó, and Peter G. W. Gettins: Active Site Distortion Is Sufficient for Proteinase Inhibition by Serpins: STRUCTURE OF THE COVALENT COMPLEX OF ${alpha}$ ₁-PROTEINASE INHIBITOR WITH PORCINE PANCREATIC ELASTASE
J. Biol. Chem. 2006 281: 3452-3457. First Published on December 1, 2005; doi:10.1074/jbc.M510564200 [Abstract] [Full Text] [PDF]

Martin Gengenbacher, Teresa B. Fitzpatrick, Thomas Raschle, Karlheinz Flicker, Irmgard Sinning, Sylke Müller, Peter Macheroux, Ivo Tews, and Barbara Kappes: Vitamin B6 Biosynthesis by the Malaria Parasite Plasmodium falciparum: BIOCHEMICAL AND STRUCTURAL INSIGHTS
J. Biol. Chem. 2006 281: 3633-3641. First Published on December 8, 2005; doi:10.1074/jbc.M508696200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Valerie M. Kramlinger and Hiroshi Hiasa: The "GyrA-box" Is Required for the Ability of DNA Gyrase to Wrap DNA and Catalyze the Supercoiling Reaction
J. Biol. Chem. 2006 281: 3738-3742. First Published on December 5, 2005; doi:10.1074/jbc.M511160200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Bernard Korzeniewski: AMP Deamination Delays Muscle Acidification during Heavy Exercise and Hypoxia
J. Biol. Chem. 2006 281: 3057-3066. First Published on November 28, 2005; doi:10.1074/jbc.M510418200 [Abstract] [Full Text] [PDF]

Karl J. Morten, Brian A. C. Ackrell, and Simon Melov: Mitochondrial Reactive Oxygen Species in Mice Lacking Superoxide Dismutase 2: ATTENUATION VIA ANTIOXIDANT TREATMENT
J. Biol. Chem. 2006 281: 3354-3359. First Published on December 2, 2005; doi:10.1074/jbc.M509261200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Dubravko Rendic, Angela Linder, Katharina Paschinger, Nicole Borth, Iain B. H. Wilson, and Gustáv Fabini: Modulation of Neural Carbohydrate Epitope Expression in Drosophila melanogaster Cells
J. Biol. Chem. 2006 281: 3343-3353. First Published on November 28, 2005; doi:10.1074/jbc.M508334200 [Abstract] [Full Text] [PDF]

Javier Andrés Juárez-Díaz, Bruce McClure, Sonia Vázquez-Santana, Arturo Guevara-García, Patricia León-Mejía, Judith Márquez-Guzmán, and Felipe Cruz-García: A Novel Thioredoxin h Is Secreted in Nicotiana alata and Reduces S-RNase in Vitro
J. Biol. Chem. 2006 281: 3418-3424. First Published on December 13, 2005; doi:10.1074/jbc.M511687200 [Abstract] [Full Text] [PDF]

Guido Veit, Birgit Kobbe, Douglas R. Keene, Mats Paulsson, Manuel Koch, and Raimund Wagener: Collagen XXVIII, a Novel von Willebrand Factor A Domain-containing Protein with Many Imperfections in the Collagenous Domain
J. Biol. Chem. 2006 281: 3494-3504. First Published on December 5, 2005; doi:10.1074/jbc.M509333200 [Abstract] [Full Text] [PDF]

Robert Sewell, Malin Bäckström, Martin Dalziel, Steven Gschmeissner, Hasse Karlsson, Thomas Noll, Jochem Gätgens, Henrik Clausen, Gunnar C. Hansson, Joy Burchell, and Joyce Taylor-Papadimitriou: The ST6GalNAc-I Sialyltransferase Localizes throughout the Golgi and Is Responsible for the Synthesis of the Tumor-associated Sialyl-Tn O-Glycan in Human Breast Cancer
J. Biol. Chem. 2006 281: 3586-3594. First Published on November 30, 2005; doi:10.1074/jbc.M511826200 [Abstract] [Full Text] [PDF]

Aleksander Hinek, Alexey V. Pshezhetsky, Mark von Itzstein, and Barry Starcher: Lysosomal Sialidase (Neuraminidase-1) Is Targeted to the Cell Surface in a Multiprotein Complex That Facilitates Elastic Fiber Assembly
J. Biol. Chem. 2006 281: 3698-3710. First Published on November 28, 2005; doi:10.1074/jbc.M508736200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Sekar Natesampillai, Martin E. Fernandez-Zapico, Raul Urrutia, and Johannes D. Veldhuis: A Novel Functional Interaction between the Sp1-like Protein KLF13 and SREBP-Sp1 Activation Complex Underlies Regulation of Low Density Lipoprotein Receptor Promoter Function
J. Biol. Chem. 2006 281: 3040-3047. First Published on November 22, 2005; doi:10.1074/jbc.M509417200 [Abstract] [Full Text] [PDF]

Karen Moreau, Eva Dizin, Hind Ray, Céline Luquain, Etienne Lefai, Fabienne Foufelle, Marc Billaud, Gilbert M. Lenoir, and Nicole Dalla Venezia: BRCA1 Affects Lipid Synthesis through Its Interaction with Acetyl-CoA Carboxylase
J. Biol. Chem. 2006 281: 3172-3181. First Published on December 2, 2005; doi:10.1074/jbc.M504652200 [Abstract] [Full Text] [PDF]

Shoji Watanabe, Shin-ichi Matsuyama, and Hajime Tokuda: Roles of the Hydrophobic Cavity and Lid of LolA in the Lipoprotein Transfer Reaction in Escherichia coli
J. Biol. Chem. 2006 281: 3335-3342. First Published on December 14, 2005; doi:10.1074/jbc.M509596200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tamotsu Tsukahara, Ryoko Tsukahara, Satoshi Yasuda, Natalia Makarova, William J. Valentine, Patrick Allison, Hongbin Yuan, Daniel L. Baker, Zaiguo Li, Robert Bittman, Abby Parrill, and Gabor Tigyi: Different Residues Mediate Recognition of 1-O-Oleyllysophosphatidic Acid and Rosiglitazone in the Ligand Binding Domain of Peroxisome Proliferator-activated Receptor ${gamma}$
J. Biol. Chem. 2006 281: 3398-3407. First Published on December 1, 2005; doi:10.1074/jbc.M510843200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Song Lu, Ying Yao, Xiangying Cheng, Sonya Mitchell, Shuangying Leng, Songmei Meng, James W. Gallagher, Gregory S. Shelness, Gabriel S. Morris, James Mahan, Sharon Frase, Charles M. Mansbach, Richard B. Weinberg, and Dennis D. Black: Overexpression of Apolipoprotein A-IV Enhances Lipid Secretion in IPEC-1 Cells by Increasing Chylomicron Size
J. Biol. Chem. 2006 281: 3473-3483. First Published on December 7, 2005; doi:10.1074/jbc.M502501200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Leonard Dode, Jens Peter Andersen, Jo Vanoevelen, Luc Raeymaekers, Ludwig Missiaen, Bente Vilsen, and Frank Wuytack: Dissection of the Functional Differences between Human Secretory Pathway Ca²⁺/Mn²⁺-ATPase (SPCA) 1 and 2 Isoenzymes by Steady-state and Transient Kinetic Analyses
J. Biol. Chem. 2006 281: 3182-3189. First Published on December 6, 2005; doi:10.1074/jbc.M511547200 [Abstract] [Full Text] [PDF]

Dieter Wicher, Hans-Jürgen Agricola, Roland Schönherr, Stefan H. Heinemann, and Christian Derst: TRP ${gamma}$ Channels Are Inhibited by cAMP and Contribute to Pacemaking in Neurosecretory Insect Neurons
J. Biol. Chem. 2006 281: 3227-3236. First Published on November 30, 2005; doi:10.1074/jbc.M511741200 [Abstract] [Full Text] [PDF]

Martin Picard, Chikashi Toyoshima, and Philippe Champeil: Effects of Inhibitors on Luminal Opening of Ca²⁺ Binding Sites in an E2P-like Complex of Sarcoplasmic Reticulum Ca2²⁺-ATPase with Be2²⁺-fluoride
J. Biol. Chem. 2006 281: 3360-3369. First Published on December 5, 2005; doi:10.1074/jbc.M511385200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Deborah Castelletti, Giulio Fracasso, Marwan Alfalah, Sara Cingarlini, Marco Colombatti, and Hassan Y. Naim: Apical Transport and Folding of Prostate-specific Membrane Antigen Occurs Independent of Glycan Processing
J. Biol. Chem. 2006 281: 3505-3512. First Published on October 12, 2005; doi:10.1074/jbc.M509460200 [Abstract] [Full Text] [PDF]

Valérie Leuranguer, Symeon Papadopoulos, and Kurt G. Beam: Organization of Calcium Channel $beta$ _1a Subunits in Triad Junctions in Skeletal Muscle
J. Biol. Chem. 2006 281: 3521-3527. First Published on November 28, 2005; doi:10.1074/jbc.M509566200 [Abstract] [Full Text] [PDF]

Ikramy A. Khalil, Kentaro Kogure, Shiroh Futaki, and Hideyoshi Harashima: High Density of Octaarginine Stimulates Macropinocytosis Leading to Efficient Intracellular Trafficking for Gene Expression
J. Biol. Chem. 2006 281: 3544-3551. First Published on December 2, 2005; doi:10.1074/jbc.M503202200 [Abstract] [Full Text] [PDF] [Supplemental Data]

John Russel McGuire, Juan Rong, Shi-Hua Li, and Xiao-Jiang Li: Interaction of Huntingtin-associated Protein-1 with Kinesin Light Chain: IMPLICATIONS IN INTRACELLULAR TRAFFICKING IN NEURONS
J. Biol. Chem. 2006 281: 3552-3559. First Published on December 8, 2005; doi:10.1074/jbc.M509806200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mario H. Barros, Alan M. Myers, Sarah Van Driesche, and Alexander Tzagoloff: COX24 Codes for a Mitochondrial Protein Required for Processing of the COX1 Transcript
J. Biol. Chem. 2006 281: 3743-3751. First Published on December 8, 2005; doi:10.1074/jbc.M510778200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Kevin A. Figueiredo, Alice L. Mui, Colleen C. Nelson, and Michael E. Cox: Relaxin Stimulates Leukocyte Adhesion and Migration through a Relaxin Receptor LGR7-dependent Mechanism
J. Biol. Chem. 2006 281: 3030-3039. First Published on November 22, 2005; doi:10.1074/jbc.M506665200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jagruti H. Patel and Steven B. McMahon: Targeting of Miz-1 Is Essential for Myc-mediated Apoptosis
J. Biol. Chem. 2006 281: 3283-3289. First Published on December 13, 2005; doi:10.1074/jbc.M513038200 [Abstract] [Full Text] [PDF]

Gregory Peignon, Sophie Thenet, Cyrille Schreider, Stéphane Fouquet, Agnès Ribeiro, Elizabeth Dussaulx, Jean Chambaz, Philippe Cardot, Martine Pinçon-Raymond, and Johanne Le Beyec: E-cadherin-dependent Transcriptional Control of Apolipoprotein A-IV Gene Expression in Intestinal Epithelial Cells: A ROLE FOR THE HEPATIC NUCLEAR FACTOR 4
J. Biol. Chem. 2006 281: 3560-3568. First Published on December 7, 2005; doi:10.1074/jbc.M506360200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ji Won Um, Do Sik Min, Hyewhon Rhim, Jongsun Kim, Seung R. Paik, and Kwang Chul Chung: Parkin Ubiquitinates and Promotes the Degradation of RanBP2
J. Biol. Chem. 2006 281: 3595-3603. First Published on December 6, 2005; doi:10.1074/jbc.M504994200 [Abstract] [Full Text] [PDF]

Rachel L. Dusek, Spiro Getsios, Feng Chen, Jung K. Park, Evangeline V. Amargo, Vincent L. Cryns, and Kathleen J. Green: The Differentiation-dependent Desmosomal Cadherin Desmoglein 1 Is a Novel Caspase-3 Target That Regulates Apoptosis in Keratinocytes
J. Biol. Chem. 2006 281: 3614-3624. First Published on November 14, 2005; doi:10.1074/jbc.M508258200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Yulong L. Chen, Ping-Yee Law, and Horace H. Loh: Sustained Activation of Phosphatidylinositol 3-Kinase/Akt/Nuclear Factor ${kappa}$ B Signaling Mediates G Protein-coupled ${delta}$ -Opioid Receptor Gene Expression
J. Biol. Chem. 2006 281: 3067-3074. First Published on November 29, 2005; doi:10.1074/jbc.M506721200 [Abstract] [Full Text] [PDF]

Wen Hao, Tomoko Takano, Julie Guillemette, Joan Papillon, Guohui Ren, and Andrey V. Cybulsky: Induction of Apoptosis by the Ste20-like Kinase SLK, a Germinal Center Kinase That Activates Apoptosis Signal-regulating Kinase and p38
J. Biol. Chem. 2006 281: 3075-3084. First Published on November 29, 2005; doi:10.1074/jbc.M511744200 [Abstract] [Full Text] [PDF]

Eva Gonzalez, Ruqin Kou, and Thomas Michel: Rac1 Modulates Sphingosine 1-Phosphate-mediated Activation of Phosphoinositide 3-Kinase/Akt Signaling Pathways in Vascular Endothelial Cells
J. Biol. Chem. 2006 281: 3210-3216. First Published on December 8, 2005; doi:10.1074/jbc.M510434200 [Abstract] [Full Text] [PDF]

Luowei Li, Keeran Sampat, Nancy Hu, Julia Zakari, and Stuart H. Yuspa: Protein Kinase C Negatively Regulates Akt Activity and Modifies UVC-induced Apoptosis in Mouse Keratinocytes
J. Biol. Chem. 2006 281: 3237-3243. First Published on December 7, 2005; doi:10.1074/jbc.M512167200 [Abstract] [Full Text] [PDF]

Guim Kwon, Connie A. Marshall, Hui Liu, Kirk L. Pappan, Maria S. Remedi, and Michael L. McDaniel: Glucose-stimulated DNA Synthesis through Mammalian Target of Rapamycin (mTOR) Is Regulated by K_ATP Channels: EFFECTS ON CELL CYCLE PROGRESSION IN RODENT ISLETS
J. Biol. Chem. 2006 281: 3261-3267. First Published on December 12, 2005; doi:10.1074/jbc.M508821200 [Abstract] [Full Text] [PDF]

Michael T. Roberts, Rachel Phelan, Beth S. Erlichman, Rathi N. Pillai, Lan Ma, Gregory F. Lopreato, and S. John Mihic: Occupancy of a Single Anesthetic Binding Pocket Is Sufficient to Enhance Glycine Receptor Function
J. Biol. Chem. 2006 281: 3305-3311. First Published on December 16, 2005; doi:10.1074/jbc.M502000200 [Abstract] [Full Text] [PDF]

Svetlana Pavlovic, Baoheng Du, Kazuko Sakamoto, K. M. Faisal Khan, Chandramohan Natarajan, Richard M. Breyer, Andrew J. Dannenberg, and Domenick J. Falcone: Targeting Prostaglandin E₂ Receptors as an Alternative Strategy to Block Cyclooxygenase-2-dependent Extracellular Matrix-induced Matrix Metalloproteinase-9 Expression by Macrophages
J. Biol. Chem. 2006 281: 3321-3328. First Published on December 7, 2005; doi:10.1074/jbc.M506846200 [Abstract] [Full Text] [PDF]

Olga A. Mareninova, Kai-Feng Sung, Peggy Hong, Aurelia Lugea, Stephen J. Pandol, Ilya Gukovsky, and Anna S. Gukovskaya: Cell Death in Pancreatitis: CASPASES PROTECT FROM NECROTIZING PANCREATITIS
J. Biol. Chem. 2006 281: 3370-3381. First Published on December 8, 2005; doi:10.1074/jbc.M511276200 [Abstract] [Full Text] [PDF]

Lee G. Henage, John H. Exton, and H. Alex Brown: Kinetic Analysis of a Mammalian Phospholipase D: ALLOSTERIC MODULATION BY MONOMERIC GTPases, PROTEIN KINASE C, AND POLYPHOSPHOINOSITIDES
J. Biol. Chem. 2006 281: 3408-3417. First Published on December 8, 2005; doi:10.1074/jbc.M508800200 [Abstract] [Full Text] [PDF]

Hyang-Sook Hoe, Ana Pocivavsek, Geetanjali Chakraborty, Zhanyan Fu, Stefano Vicini, Michael D. Ehlers, and G. William Rebeck: Apolipoprotein E Receptor 2 Interactions with the N-Methyl-D-aspartate Receptor
J. Biol. Chem. 2006 281: 3425-3431. First Published on December 6, 2005; doi:10.1074/jbc.M509380200 [Abstract] [Full Text] [PDF]

Susan M. Hanson and Vsevolod V. Gurevich: The Differential Engagement of Arrestin Surface Charges by the Various Functional Forms of the Receptor
J. Biol. Chem. 2006 281: 3458-3462. First Published on December 8, 2005; doi:10.1074/jbc.M512148200 [Abstract] [Full Text] [PDF]

Eduardo Torres and Michael K. Rosen: Protein-tyrosine Kinase and GTPase Signals Cooperate to Phosphorylate and Activate Wiskott-Aldrich Syndrome Protein (WASP)/Neuronal WASP
J. Biol. Chem. 2006 281: 3513-3520. First Published on November 17, 2005; doi:10.1074/jbc.M509416200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Run Shen, Mo Chen, Yong-Jun Wang, Hiroyuki Kaneki, Lianping Xing, Regis J. O'Keefe, and Di Chen: Smad6 Interacts with Runx2 and Mediates Smad Ubiquitin Regulatory Factor 1-induced Runx2 Degradation
J. Biol. Chem. 2006 281: 3569-3576. First Published on November 18, 2005; doi:10.1074/jbc.M506761200 [Abstract] [Full Text] [PDF]

Jun Cai, Wen G. Jiang, Maria B. Grant, and Mike Boulton: Pigment Epithelium-derived Factor Inhibits Angiogenesis via Regulated Intracellular Proteolysis of Vascular Endothelial Growth Factor Receptor 1
J. Biol. Chem. 2006 281: 3604-3613. First Published on December 8, 2005; doi:10.1074/jbc.M507401200 [Abstract] [Full Text] [PDF]

Gipsy Majumdar, Adrienne Harrington, James Hungerford, Antonio Martinez-Hernandez, Ivan C. Gerling, Rajendra Raghow, and Solomon Solomon: Insulin Dynamically Regulates Calmodulin Gene Expression by Sequential O-Glycosylation and Phosphorylation of Sp1 and Its Subcellular Compartmentalization in Liver Cells
J. Biol. Chem. 2006 281: 3642-3650. First Published on December 6, 2005; doi:10.1074/jbc.M511223200 [Abstract] [Full Text] [PDF]

Keqiang Chen, Pablo Iribarren, Jinyue Hu, Jianhong Chen, Wanghua Gong, Edward H. Cho, Stephen Lockett, Nancy M. Dunlop, and Ji Ming Wang: Activation of Toll-like Receptor 2 on Microglia Promotes Cell Uptake of Alzheimer Disease-associated Amyloid $beta$ Peptide
J. Biol. Chem. 2006 281: 3651-3659. First Published on December 9, 2005; doi:10.1074/jbc.M508125200 [Abstract] [Full Text] [PDF]

Marie-France Lisé, Tak Pan Wong, Alex Trinh, Rochelle M. Hines, Lidong Liu, Rujun Kang, Dustin J. Hines, Jie Lu, James R. Goldenring, Yu Tian Wang, and Alaa El-Husseini: Involvement of Myosin Vb in Glutamate Receptor Trafficking
J. Biol. Chem. 2006 281: 3669-3678. First Published on December 7, 2005; doi:10.1074/jbc.M511725200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ambrus Toth, Philip Nickson, Liu Liang Qin, and Peter Erhardt: Differential Regulation of Cardiomyocyte Survival and Hypertrophy by MDM2, an E3 Ubiquitin Ligase
J. Biol. Chem. 2006 281: 3679-3689. First Published on December 8, 2005; doi:10.1074/jbc.M509630200 [Abstract] [Full Text] [PDF]

Dong-Wan Seo, Hongmei Li, Cheng-Kui Qu, Junseo Oh, Young-Sik Kim, Tere Diaz, Beiyang Wei, Jeung-Whan Han, and William G. Stetler-Stevenson: Shp-1 Mediates the Antiproliferative Activity of Tissue Inhibitor of Metalloproteinase-2 in Human Microvascular Endothelial Cells
J. Biol. Chem. 2006 281: 3711-3721. First Published on December 2, 2005; doi:10.1074/jbc.M509932200 [Abstract] [Full Text] [PDF]

Cunnigaiper D. Bhanumathy, Steven K. Nakao, and Suresh K. Joseph: Mechanism of Proteasomal Degradation of Inositol Trisphosphate Receptors in CHO-K1 Cells
J. Biol. Chem. 2006 281: 3722-3730. First Published on November 29, 2005; doi:10.1074/jbc.M509966200 [Abstract] [Full Text] [PDF]

M. Tariq Khan, Larry Wagner, II, David I. Yule, Cunnigaiper Bhanumathy, and Suresh K. Joseph: Akt Kinase Phosphorylation of Inositol 1,4,5-Trisphosphate Receptors
J. Biol. Chem. 2006 281: 3731-3737. First Published on December 6, 2005; doi:10.1074/jbc.M509262200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Michael J. Crawford and Daniel E. Goldberg: Regulation of the Salmonella typhimurium flavohemoglobin gene. A NEW PATHWAY FOR BACTERIAL GENE EXPRESSION IN RESPONSE TO NITRIC OXIDE. VOLUME 273 (1998) PAGES 34028-34032
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Stephen M. Waters, Robbin M. Brodbeck, Jeremy Steflik, Jianying Yu, Carolyn Baltazar, Amy E. Peck, Daniel Severance, Lu Yan Zhang, Kevin Currie, Bertrand L. Chenard, Alan J. Hutchison, George Maynard, and James E. Krause: Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction. VOLUME 280 (2005) PAGES 40617-40623
J. Biol. Chem. 2006 281: 3752-a. [Full Text] [PDF]