JBC -- Table of Contents (Jul 20 2007, 282, (29))

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Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Cyanate Chemistry, Enzyme Mechanisms, and Gene Amplification: the Work of George R. Stark
Reactions of the Cyanate Present in Aqueous Urea with Amino Acids and Proteins (George R. Stark, William H. Stein, and Stanford Moore J. Biol. Chem. 235, 3177-3181)
Aspartate Transcarbamylase. INTERACTION WITH THE TRANSITION STATE ANALOGUE N-(PHOSPHONACETYL)-l-ASPARTATE (Kim D. Collins and George R. Stark J. Biol. Chem. 246, 6599-6605)
Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells (G. M. Wahl, R. A. Padgett, and G. R. Stark J. Biol. Chem. 254, 8679-8689)
J. Biol. Chem. 2007 282: e23. [Full Text]

Minireviews:

H. Patrick McNeil, Roberto Adachi, and Richard L. Stevens: Mast Cell-restricted Tryptases: Structure and Function in Inflammation and Pathogen Defense
J. Biol. Chem. 2007 282: 20785-20789. First Published on May 15, 2007; doi:10.1074/jbc.R700017200 [Abstract] [Full Text] [PDF]

Accelerated Publications:

James E. Hansen, Chung-Ming Tse, Grace Chan, Emil R. Heinze, Robert N. Nishimura, and Richard H. Weisbart,: Intranuclear Protein Transduction through a Nucleoside Salvage Pathway
J. Biol. Chem. 2007 282: 20790-20793. First Published on May 24, 2007; doi:10.1074/jbc.C700090200 [Abstract] [Full Text] [PDF]

Jee Hyun Um, Shutong Yang, Shin Yamazaki, Hyeog Kang, Benoit Viollet, Marc Foretz, and Jay H. Chung: Activation of 5'-AMP-activated Kinase with Diabetes Drug Metformin Induces Casein Kinase I ${epsilon}$ (CKI ${epsilon}$ )-dependent Degradation of Clock Protein mPer2
J. Biol. Chem. 2007 282: 20794-20798. First Published on May 24, 2007; doi:10.1074/jbc.C700070200 [Abstract] [Full Text] [PDF]

Markey C. McNutt, Thomas A. Lagace, and Jay D. Horton: Catalytic Activity Is Not Required for Secreted PCSK9 to Reduce Low Density Lipoprotein Receptors in HepG2 Cells
J. Biol. Chem. 2007 282: 20799-20803. First Published on May 29, 2007; doi:10.1074/jbc.C700095200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Georgios Skiniotis, Danesh Moazed, and Thomas Walz: Acetylated Histone Tail Peptides Induce Structural Rearrangements in the RSC Chromatin Remodeling Complex
J. Biol. Chem. 2007 282: 20804-20808. First Published on May 29, 2007; doi:10.1074/jbc.C700081200 [Abstract] [Full Text] [PDF] [Supplemental Data]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Yasushi Shiomi, Chikahide Masutani, Fumio Hanaoka, Hiroshi Kimura, and Toshiki Tsurimoto: A Second Proliferating Cell Nuclear Antigen Loader Complex, Ctf18-Replication Factor C, Stimulates DNA Polymerase ${eta}$ Activity
J. Biol. Chem. 2007 282: 20906-20914. First Published on May 31, 2007; doi:10.1074/jbc.M610102200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Olga M. Mazina, Matthew J. Rossi, Nicolas H. Thomaä, and Alexander V. Mazin: Interactions of Human Rad54 Protein with Branched DNA Molecules
J. Biol. Chem. 2007 282: 21068-21080. First Published on May 31, 2007; doi:10.1074/jbc.M701992200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ilker Donmez, Vaishnavi Rajagopal, Yong-Joo Jeong, and Smita S. Patel: Nucleic Acid Unwinding by Hepatitis C Virus and Bacteriophage T7 Helicases Is Sensitive to Base Pair Stability
J. Biol. Chem. 2007 282: 21116-21123. First Published on May 15, 2007; doi:10.1074/jbc.M702136200 [Abstract] [Full Text] [PDF]

Gary D. Kao, Zibin Jiang, Anne Marie Fernandes, Anjali K. Gupta, and Amit Maity: Inhibition of Phosphatidylinositol-3-OH Kinase/Akt Signaling Impairs DNA Repair in Glioblastoma Cells following Ionizing Radiation
J. Biol. Chem. 2007 282: 21206-21212. First Published on May 18, 2007; doi:10.1074/jbc.M703042200 [Abstract] [Full Text] [PDF]

Transcription, Chromatin, and Epigenetics:

TaeSoo Kim and Stephen Buratowski: Two Saccharomyces cerevisiae JmjC Domain Proteins Demethylate Histone H3 Lys³⁶ in Transcribed Regions to Promote Elongation
J. Biol. Chem. 2007 282: 20827-20835. First Published on May 24, 2007; doi:10.1074/jbc.M703034200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Thi Lien-Anh Nguyên, Stéphane de Walque, Emmanuelle Veithen, Ann Dekoninck, Valérie Martinelli, Yvan de Launoit, Arsène Burny, Robert Harrod, and Carine Van Lint: Transcriptional Regulation of the Bovine Leukemia Virus Promoter by the Cyclic AMP-response Element Modulator ${tau}$ Isoform
J. Biol. Chem. 2007 282: 20854-20867. First Published on May 25, 2007; doi:10.1074/jbc.M703060200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xiaowei Liu, Bo Wu, Jaroslaw Szary, Eric M. Kofoed, and Fred Schaufele: Functional Sequestration of Transcription Factor Activity by Repetitive DNA
J. Biol. Chem. 2007 282: 20868-20876. First Published on May 25, 2007; doi:10.1074/jbc.M702547200 [Abstract] [Full Text] [PDF]

Manish Sharma, Anuja A. George, Badri N. Singh, Naresh C. Sahoo, and Kanury V. S. Rao: Regulation of Transcript Elongation through Cooperative and Ordered Recruitment of Cofactors
J. Biol. Chem. 2007 282: 20887-20896. First Published on May 29, 2007; doi:10.1074/jbc.M701420200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anastasia Rogaeva, Xiao-Ming Ou, Hamed Jafar-Nejad, Sylvie Lemonde, and Paul R. Albert: Differential Repression by Freud-1/CC2D1A at a Polymorphic Site in the Dopamine-D2 Receptor Gene
J. Biol. Chem. 2007 282: 20897-20905. First Published on May 29, 2007; doi:10.1074/jbc.M610038200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jongkyu Choi, Bong Kim, Kyu Heo, Kyunghwan Kim, Hyunjung Kim, Yuxia Zhan, Jeffrey A. Ranish, and Woojin An: Purification and Characterization of Cellular Proteins Associated with Histone H4 Tails
J. Biol. Chem. 2007 282: 21024-21031. First Published on June 4, 2007; doi:10.1074/jbc.M703883200 [Abstract] [Full Text] [PDF]

Geoffrey Gloire, Julie Horion, Nadia El Mjiyad, Françoise Bex, Alain Chariot, Emmanuel Dejardin, and Jacques Piette: Promoter-dependent Effect of IKK ${alpha}$ on NF- ${kappa}$ B/p65 DNA Binding
J. Biol. Chem. 2007 282: 21308-21318. First Published on May 30, 2007; doi:10.1074/jbc.M610728200 [Abstract] [Full Text] [PDF]

Victoria M. Cook and Pieter L. deHaseth: Strand Opening-deficient Escherichia coli RNA Polymerase Facilitates Investigation of Closed Complexes with Promoter DNA: EFFECTS OF DNA SEQUENCE AND TEMPERATURE
J. Biol. Chem. 2007 282: 21319-21326. First Published on May 16, 2007; doi:10.1074/jbc.M702232200 [Abstract] [Full Text] [PDF]

RNA: Processing and Catalysis:

Elizabeth J. Fialcowitz-White, Brandy Y. Brewer, Jeff D. Ballin, Chris D. Willis, Eric A. Toth, and Gerald M. Wilson: Specific Protein Domains Mediate Cooperative Assembly of HuR Oligomers on AU-rich mRNA-destabilizing Sequences
J. Biol. Chem. 2007 282: 20948-20959. First Published on May 21, 2007; doi:10.1074/jbc.M701751200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Fang Wei, Hans R. Schöler, and Michael L. Atchison: Sumoylation of Oct4 Enhances Its Stability, DNA Binding, and Transactivation
J. Biol. Chem. 2007 282: 21551-21560. First Published on May 24, 2007; doi:10.1074/jbc.M611041200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translational Modification, and Degradation:

Sergey A. Shiryaev, Albert G. Remacle, Boris I. Ratnikov, Nicholas A. Nelson, Alexei Y. Savinov, Ge Wei, Massimo Bottini, Michele F. Rega, Amelie Parent, Roxane Desjardins, Martin Fugere, Robert Day, Mojgan Sabet, Maurizio Pellecchia, Robert C. Liddington, Jeffrey W. Smith, Tomas Mustelin, Donald G. Guiney, Michal Lebl, and Alex Y. Strongin: Targeting Host Cell Furin Proprotein Convertases as a Therapeutic Strategy against Bacterial Toxins and Viral Pathogens
J. Biol. Chem. 2007 282: 20847-20853. First Published on May 30, 2007; doi:10.1074/jbc.M703847200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Selina Khan, Martijn S. Bijker, Jimmy J. Weterings, Hans J. Tanke, Gosse J. Adema, Thorbald van Hall, Jan W. Drijfhout, Cornelis J. M. Melief, Hermen S. Overkleeft, Gijsbert A. van der Marel, Dmitri V. Filippov, Sjoerd H. van der Burg, and Ferry Ossendorp: Distinct Uptake Mechanisms but Similar Intracellular Processing of Two Different Toll-like Receptor Ligand-Peptide Conjugates in Dendritic Cells
J. Biol. Chem. 2007 282: 21145-21159. First Published on April 26, 2007; doi:10.1074/jbc.M701705200 [Abstract] [Full Text] [PDF]

Sonia Bañuelos, Miren J. Omaetxebarria, Isbaal Ramos, Martin R. Larsen, Igor Arregi, Ole N. Jensen, Jesus M. Arizmendi, Adelina Prado, and Arturo Muga: Phosphorylation of Both Nucleoplasmin Domains Is Required for Activation of Its Chromatin Decondensation Activity
J. Biol. Chem. 2007 282: 21213-21221. First Published on May 17, 2007; doi:10.1074/jbc.M702842200 [Abstract] [Full Text] [PDF]

Rivka L. Isaacson, Valerie E. Pye, Peter Simpson, Hemmo H. Meyer, Xiaodong Zhang, Paul S. Freemont, and Steve Matthews: Detailed Structural Insights into the p97-Npl4-Ufd1 Interface
J. Biol. Chem. 2007 282: 21361-21369. First Published on May 9, 2007; doi:10.1074/jbc.M610069200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Christopher S. Reigstad, Scott J. Hultgren, and Jeffrey I. Gordon: Functional Genomic Studies of Uropathogenic Escherichia coli and Host Urothelial Cells when Intracellular Bacterial Communities Are Assembled
J. Biol. Chem. 2007 282: 21259-21267. First Published on May 14, 2007; doi:10.1074/jbc.M611502200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Shakeel M. Thakurdas, Ernestina Melicoff, Leticia Sansores-Garcia, Daniel C. Moreira, Youlia Petrova, Richard L. Stevens, and Roberto Adachi: The Mast Cell-restricted Tryptase mMCP-6 Has a Critical Immunoprotective Role in Bacterial Infections
J. Biol. Chem. 2007 282: 20809-20815. First Published on April 23, 2007; doi:10.1074/jbc.M611842200 [Abstract] [Full Text] [PDF]

Nuria Jiménez-Juárez, Carlos Muñoz-Garay, Isabel Gómez, Gloria Saab-Rincon, Juanita Y. Damian-Almazo, Sarjeet S. Gill, Mario Soberón, and Alejandra Bravo: Bacillus thuringiensis Cry1Ab Mutants Affecting Oligomer Formation Are Non-toxic to Manduca sexta Larvae
J. Biol. Chem. 2007 282: 21222-21229. First Published on May 30, 2007; doi:10.1074/jbc.M701314200 [Abstract] [Full Text] [PDF]

Erik Sandelin, Anna Nordlund, Peter M. Andersen, Stefan S. L. Marklund, and Mikael Oliveberg: Amyotrophic Lateral Sclerosis-associated Copper/Zinc Superoxide Dismutase Mutations Preferentially Reduce the Repulsive Charge of the Proteins
J. Biol. Chem. 2007 282: 21230-21236. First Published on May 18, 2007; doi:10.1074/jbc.M700765200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Keith A. Stubbs, Misty Balcewich, Brian L. Mark, and David J. Vocadlo: Small Molecule Inhibitors of a Glycoside Hydrolase Attenuate Inducible AmpC-mediated $beta$ -Lactam Resistance
J. Biol. Chem. 2007 282: 21382-21391. First Published on April 16, 2007; doi:10.1074/jbc.M700084200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Nathalie Méthot, Joel Rubin, Daniel Guay, Christian Beaulieu, Diane Ethier, T. Jagadeeswar Reddy, Denis Riendeau, and M. David Percival: Inhibition of the Activation of Multiple Serine Proteases with a Cathepsin C Inhibitor Requires Sustained Exposure to Prevent Pro-enzyme Processing
J. Biol. Chem. 2007 282: 20836-20846. First Published on May 29, 2007; doi:10.1074/jbc.M702615200 [Abstract] [Full Text] [PDF] [Supplemental Data]

François J. M. Chartier and Manon Couture: Substrate-specific Interactions with the Heme-bound Oxygen Molecule of Nitric-oxide Synthase
J. Biol. Chem. 2007 282: 20877-20886. First Published on May 30, 2007; doi:10.1074/jbc.M701800200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Minghao Jin, Quan Yuan, Songhua Li, and Gabriel H. Travis: Role of LRAT on the Retinoid Isomerase Activity and Membrane Association of Rpe65
J. Biol. Chem. 2007 282: 20915-20924. First Published on May 15, 2007; doi:10.1074/jbc.M701432200 [Abstract] [Full Text] [PDF]

Namthip Sitachitta, Nicole B. Lopanik, Yingqing Mao, and David H. Sherman: Analysis of a Parallel Branch in the Mitomycin Biosynthetic Pathway Involving the mitN-Encoded Aziridine N-Methyltransferase
J. Biol. Chem. 2007 282: 20941-20947. First Published on May 16, 2007; doi:10.1074/jbc.M702456200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gareth J. Wayne, Su-Jun Deng, Augustin Amour, Satty Borman, Rosalie Matico, H. Luke Carter, and Gillian Murphy: TIMP-3 Inhibition of ADAMTS-4 (Aggrecanase-1) Is Modulated by Interactions between Aggrecan and the C-terminal Domain of ADAMTS-4
J. Biol. Chem. 2007 282: 20991-20998. First Published on April 30, 2007; doi:10.1074/jbc.M610721200 [Abstract] [Full Text] [PDF]

Li Yi and Stephen W. Ragsdale: Evidence That the Heme Regulatory Motifs in Heme Oxygenase-2 Serve as a Thiol/Disulfide Redox Switch Regulating Heme Binding
J. Biol. Chem. 2007 282: 21056-21067. First Published on May 31, 2007; doi:10.1074/jbc.M700664200 [Abstract] [Full Text] [PDF] [Supplemental Data]

László Beinrohr, Veronika Harmat, József Dobó, Zsolt Lörincz, Péter Gál, and Péter Závodszky: C1 Inhibitor Serpin Domain Structure Reveals the Likely Mechanism of Heparin Potentiation and Conformational Disease
J. Biol. Chem. 2007 282: 21100-21109. First Published on May 8, 2007; doi:10.1074/jbc.M700841200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bo Li and Wilfred A. van der Donk: Identification of Essential Catalytic Residues of the Cyclase NisC Involved in the Biosynthesis of Nisin
J. Biol. Chem. 2007 282: 21169-21175. First Published on May 19, 2007; doi:10.1074/jbc.M701802200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Karin E. van Straaten, Thomas R. M. Barends, Bauke W. Dijkstra, and Andy-Mark W. H. Thunnissen: Structure of Escherichia coli Lytic Transglycosylase MltA with Bound Chitohexaose: IMPLICATIONS FOR PEPTIDOGLYCAN BINDING AND CLEAVAGE
J. Biol. Chem. 2007 282: 21197-21205. First Published on May 14, 2007; doi:10.1074/jbc.M701818200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Atsunari Tanaka, Hiroto Takahashi, and Toru Shimizu: Critical Role of the Heme Axial Ligand, Met⁹⁵, in Locking Catalysis of the Phosphodiesterase from Escherichia coli (Ec DOS) toward Cyclic diGMP
J. Biol. Chem. 2007 282: 21301-21307. First Published on May 29, 2007; doi:10.1074/jbc.M701920200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gijsbert M. Grotenbreg, Melissa J. Nicholson, Kevin D. Fowler, Kathrin Wilbuer, Leah Octavio, Maxine Yang, Arup K. Chakraborty, Hidde L. Ploegh, and Kai W. Wucherpfennig: Empty Class II Major Histocompatibility Complex Created by Peptide Photolysis Establishes the Role of DM in Peptide Association
J. Biol. Chem. 2007 282: 21425-21436. First Published on May 24, 2007; doi:10.1074/jbc.M702844200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nicolas Doucet, Pierre-Yves Savard, Joelle N. Pelletier, and Stéphane M. Gagné: NMR Investigation of Tyr¹⁰⁵ Mutants in TEM-1 $beta$ -Lactamase: DYNAMICS ARE CORRELATED WITH FUNCTION
J. Biol. Chem. 2007 282: 21448-21459. First Published on April 10, 2007; doi:10.1074/jbc.M609777200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Markus C. Gershater, Ian Cummins, and Robert Edwards: Role of a Carboxylesterase in Herbicide Bioactivation in Arabidopsis thaliana
J. Biol. Chem. 2007 282: 21460-21466. First Published on May 22, 2007; doi:10.1074/jbc.M701985200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Indranil Basu, Grace Cordovano, Ishita Das, Thomas J. Belbin, Chandan Guha, and Vern L. Schramm: A Transition State Analogue of 5'-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
J. Biol. Chem. 2007 282: 21477-21486. First Published on June 4, 2007; doi:10.1074/jbc.M702287200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolism and Bioenergetics:

Chengshu Wang and Raymond J. St. Leger: The Metarhizium anisopliae Perilipin Homolog MPL1 Regulates Lipid Metabolism, Appressorial Turgor Pressure, and Virulence
J. Biol. Chem. 2007 282: 21110-21115. First Published on May 25, 2007; doi:10.1074/jbc.M609592200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Geert A. Martens, Annelies Vervoort, Mark Van de Casteele, Geert Stangé, Karine Hellemans, Hong Vien Van Thi, Frans Schuit, and Daniël Pipeleers: Specificity in Beta Cell Expression of L-3-Hydroxyacyl-CoA Dehydrogenase, Short Chain, and Potential Role in Down-regulating Insulin Release
J. Biol. Chem. 2007 282: 21134-21144. First Published on May 9, 2007; doi:10.1074/jbc.M700083200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Tobias Schulz, Udo Schumacher, and Peter Prehm: Hyaluronan Export by the ABC Transporter MRP5 and Its Modulation by Intracellular cGMP
J. Biol. Chem. 2007 282: 20999-21004. First Published on May 31, 2007; doi:10.1074/jbc.M700915200 [Abstract] [Full Text] [PDF]

Sindhulakshmi Kurup, Tessa J. M. Wijnhoven, Guido J. Jenniskens, Koji Kimata, Hiroko Habuchi, Jin-ping Li, Ulf Lindahl, Toin H. van Kuppevelt, and Dorothe Spillmann: Characterization of Anti-heparan Sulfate Phage Display Antibodies AO4B08 and HS4E4
J. Biol. Chem. 2007 282: 21032-21042. First Published on May 21, 2007; doi:10.1074/jbc.M702073200 [Abstract] [Full Text] [PDF]

Hiroko Ideo, Akira Seko, and Katsuko Yamashita: Recognition Mechanism of Galectin-4 for Cholesterol 3-Sulfate
J. Biol. Chem. 2007 282: 21081-21089. First Published on June 1, 2007; doi:10.1074/jbc.M703770200 [Abstract] [Full Text] [PDF]

Karen K. McKee, David Harrison, Stephanie Capizzi, and Peter D. Yurchenco: Role of Laminin Terminal Globular Domains in Basement Membrane Assembly
J. Biol. Chem. 2007 282: 21437-21447. First Published on May 21, 2007; doi:10.1074/jbc.M702963200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lipids and Lipoproteins:

Pascal Degrace, Laurent Demizieux, Zhen-yu Du, Joseph Gresti, Laurent Caverot, Louiza Djaouti, Tony Jourdan, Bastien Moindrot, Jean-Claude Guilland, Jean-François Hocquette, and Pierre Clouet: Regulation of Lipid Flux between Liver and Adipose Tissue during Transient Hepatic Steatosis in Carnitine-depleted Rats
J. Biol. Chem. 2007 282: 20816-20826. First Published on May 12, 2007; doi:10.1074/jbc.M611391200 [Abstract] [Full Text] [PDF]

Norimasa Tamehiro, Yukari Shigemoto-Mogami, Tomoshi Kakeya, Kei-ichiro Okuhira, Kazuhiro Suzuki, Ryuichiro Sato, Taku Nagao, and Tomoko Nishimaki-Mogami: Sterol Regulatory Element-binding Protein-2- and Liver X Receptor-driven Dual Promoter Regulation of Hepatic ABC Transporter A1 Gene Expression: MECHANISM UNDERLYING THE UNIQUE RESPONSE TO CELLULAR CHOLESTEROL STATUS
J. Biol. Chem. 2007 282: 21090-21099. First Published on May 27, 2007; doi:10.1074/jbc.M701228200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Michael S. Huang, Sean Morony, Jinxiu Lu, Zina Zhang, Olga Bezouglaia, Wendy Tseng, Sotirios Tetradis, Linda L. Demer, and Yin Tintut: Atherogenic Phospholipids Attenuate Osteogenic Signaling by BMP-2 and Parathyroid Hormone in Osteoblasts
J. Biol. Chem. 2007 282: 21237-21243. First Published on May 22, 2007; doi:10.1074/jbc.M701341200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Wei Zhang, Edgar Zitron, Meike Hömme, Lars Kihm, Christian Morath, Daniel Scherer, Stephan Hegge, Dierk Thomas, Claus P. Schmitt, Martin Zeier, Hugo Katus, Christoph Karle, and Vedat Schwenger: Aquaporin-1 Channel Function Is Positively Regulated by Protein Kinase C
J. Biol. Chem. 2007 282: 20933-20940. First Published on May 23, 2007; doi:10.1074/jbc.M703858200 [Abstract] [Full Text] [PDF]

Liming Shu and James A. Shayman: Caveolin-associated Accumulation of Globotriaosylceramide in the Vascular Endothelium of ${alpha}$ -Galactosidase A Null Mice
J. Biol. Chem. 2007 282: 20960-20967. First Published on May 29, 2007; doi:10.1074/jbc.M702436200 [Abstract] [Full Text] [PDF]

Zhenhui Chen, Brandy L. Akin, and Larry R. Jones: Mechanism of Reversal of Phospholamban Inhibition of the Cardiac Ca²⁺-ATPase by Protein Kinase A and by Anti-phospholamban Monoclonal Antibody 2D12
J. Biol. Chem. 2007 282: 20968-20976. First Published on June 4, 2007; doi:10.1074/jbc.M703516200 [Abstract] [Full Text] [PDF]

Naganand Rayapuram,, Jérémie Hagenmuller,, Jean-Michel Grienenberger, Philippe Giegé, and Géraldine Bonnard: AtCCMA Interacts with AtCcmB to Form a Novel Mitochondrial ABC Transporter Involved in Cytochrome c Maturation in Arabidopsis
J. Biol. Chem. 2007 282: 21015-21023. First Published on June 5, 2007; doi:10.1074/jbc.M704091200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Fábio Dupart Nascimento, Mirian A. F. Hayashi, Alexandre Kerkis, Vitor Oliveira, Eduardo B. Oliveira, Gandhi Rádis-Baptista, Helena Bonciani Nader, Tetsuo Yamane, Ivarne Luis dos Santos Tersariol, and Irina Kerkis: Crotamine Mediates Gene Delivery into Cells through the Binding to Heparan Sulfate Proteoglycans
J. Biol. Chem. 2007 282: 21349-21360. First Published on May 9, 2007; doi:10.1074/jbc.M604876200 [Abstract] [Full Text] [PDF]

Yoshihito Fujita, Ainan Xu, Li Xie, Lakshmanan Arunachalam, Ting-Chieh Chou, Tiandan Jiang, Soon-Kwang Chiew, John Kourtesis, Li Wang, Herbert Y. Gaisano, and Shuzo Sugita: Ca²⁺-dependent Activator Protein for Secretion 1 Is Critical for Constitutive and Regulated Exocytosis but Not for Loading of Transmitters into Dense Core Vesicles
J. Biol. Chem. 2007 282: 21392-21403. First Published on May 31, 2007; doi:10.1074/jbc.M703699200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jocelyn Bédard, Sybille Kubis, Sarat Bimanadham, and Paul Jarvis: Functional Similarity between the Chloroplast Translocon Component, Tic40, and the Human Co-chaperone, Hsp70-interacting Protein (Hip)
J. Biol. Chem. 2007 282: 21404-21414. First Published on May 29, 2007; doi:10.1074/jbc.M611545200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sixue Chen, Rocío Sánchez-Fernández, Elise R. Lyver, Andrew Dancis, and Philip A. Rea: Functional Characterization of AtATM1, AtATM2, and AtATM3, a Subfamily of Arabidopsis Half-molecule ATP-binding Cassette Transporters Implicated in Iron Homeostasis
J. Biol. Chem. 2007 282: 21561-21571. First Published on May 21, 2007; doi:10.1074/jbc.M702383200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Victoria A. Payne, Wo-Shing Au, Sarah L. Gray, Edoardo Dalla Nora, Shaikh M. Rahman, Rebecca Sanders, Dirk Hadaschik, Jacob E. Friedman, Stephen O'Rahilly, and Justin J. Rochford: Sequential Regulation of Diacylglycerol Acyltransferase 2 Expression by CAAT/Enhancer-binding Protein $beta$ (C/EBP $beta$ ) and C/EBP ${alpha}$ during Adipogenesis
J. Biol. Chem. 2007 282: 21005-21014. First Published on May 14, 2007; doi:10.1074/jbc.M702871200 [Abstract] [Full Text] [PDF]

Dan Liu, Xia Ding, Jian Du, Xin Cai, Yuejia Huang, Tarsha Ward, Andrew Shaw, Yong Yang, Renming Hu, Changjiang Jin, and Xuebiao Yao: Human NUF2 Interacts with Centromere-associated Protein E and Is Essential for a Stable Spindle Microtubule-Kinetochore Attachment
J. Biol. Chem. 2007 282: 21415-21424. First Published on May 29, 2007; doi:10.1074/jbc.M609026200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nathan C. Geething and James A. Spudich: Identification of a Minimal Myosin Va Binding Site within an Intrinsically Unstructured Domain of Melanophilin
J. Biol. Chem. 2007 282: 21518-21528. First Published on May 19, 2007; doi:10.1074/jbc.M701932200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Lola Maksumova, Yanni Wang, Nelson K. Y. Wong, Hoa T. Le, Catherine J. Pallen, and Pauline Johnson: Differential Function of PTP ${alpha}$ and PTP ${alpha}$ Y789F in T Cells and Regulation of PTP ${alpha}$ Phosphorylation at Tyr-789 by CD45
J. Biol. Chem. 2007 282: 20925-20932. First Published on May 16, 2007; doi:10.1074/jbc.M703157200 [Abstract] [Full Text] [PDF]

Isabelle Andres-Enguix, Alex Caley, Raquel Yustos, Mark A. Schumacher, Pietro D. Spanu, Robert Dickinson, Mervyn Maze, and Nicholas P. Franks: Determinants of the Anesthetic Sensitivity of Two-pore Domain Acid-sensitive Potassium Channels: MOLECULAR CLONING OF AN ANESTHETIC-ACTIVATED POTASSIUM CHANNEL FROM LYMNAEA STAGNALIS
J. Biol. Chem. 2007 282: 20977-20990. First Published on June 4, 2007; doi:10.1074/jbc.M610692200 [Abstract] [Full Text] [PDF]

Michael E. Hildebrand, Laurence S. David, Jawed Hamid, Kirk Mulatz, Esperanza Garcia, Gerald W. Zamponi, and Terrance P. Snutch: Selective Inhibition of Cav3.3 T-type Calcium Channels by G ${alpha}$ _q/11-coupled Muscarinic Acetylcholine Receptors
J. Biol. Chem. 2007 282: 21043-21055. First Published on May 29, 2007; doi:10.1074/jbc.M611809200 [Abstract] [Full Text] [PDF]

Syed Mohammad Moin, Milena Panteva, and Shahid Jameel: The Hepatitis E Virus Orf3 Protein Protects Cells from Mitochondrial Depolarization and Death
J. Biol. Chem. 2007 282: 21124-21133. First Published on May 8, 2007; doi:10.1074/jbc.M701696200 [Abstract] [Full Text] [PDF]

Ana M. Laxalt, Nicolás Raho, Arjen ten Have, and Lorenzo Lamattina: Nitric Oxide Is Critical for Inducing Phosphatidic Acid Accumulation in Xylanase-elicited Tomato Cells
J. Biol. Chem. 2007 282: 21160-21168. First Published on May 9, 2007; doi:10.1074/jbc.M701212200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Robert J. Southgate, Bronwyn Neill, Oja Prelovsek, Assam El-Osta, Yasutomi Kamei, Shinji Miura, Osamu Ezaki, Thomas J. McLoughlin, Wenwei Zhang, Terry G. Unterman, and Mark A. Febbraio: FOXO1 Regulates the Expression of 4E-BP1 and Inhibits mTOR Signaling in Mammalian Skeletal Muscle
J. Biol. Chem. 2007 282: 21176-21186. First Published on May 17, 2007; doi:10.1074/jbc.M702039200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Andrea W. Tu and Kunxin Luo: Acetylation of Smad2 by the Co-activator p300 Regulates Activin and Transforming Growth Factor $beta$ Response
J. Biol. Chem. 2007 282: 21187-21196. First Published on May 3, 2007; doi:10.1074/jbc.M700085200 [Abstract] [Full Text] [PDF]

Lisa K. Mullany, Christopher J. Nelsen, Eric A. Hanse, Melissa M. Goggin, Chelsea K. Anttila, Mark Peterson, Peter B. Bitterman, Arvind Raghavan, Gretchen S. Crary, and Jeffrey H. Albrecht: Akt-mediated Liver Growth Promotes Induction of Cyclin E through a Novel Translational Mechanism and a p21-mediated Cell Cycle Arrest
J. Biol. Chem. 2007 282: 21244-21252. First Published on May 21, 2007; doi:10.1074/jbc.M702110200 [Abstract] [Full Text] [PDF]

Ping Gong, Junhai Han, Keith Reddig, and Hong-Sheng Li: A Potential Dimerization Region of dCAMTA Is Critical for Termination of Fly Visual Response
J. Biol. Chem. 2007 282: 21253-21258. First Published on May 30, 2007; doi:10.1074/jbc.M701223200 [Abstract] [Full Text] [PDF]

Meiguo Xin, Fengqin Gao, W. Stratford May, Tammy Flagg, and Xingming Deng: Protein Kinase C ${zeta}$ Abrogates the Proapoptotic Function of Bax through Phosphorylation
J. Biol. Chem. 2007 282: 21268-21277. First Published on May 24, 2007; doi:10.1074/jbc.M701613200 [Abstract] [Full Text] [PDF]

Xiong Su, Chen Kong, and Philip D. Stahl: GAPex-5 Mediates Ubiquitination, Trafficking, and Degradation of Epidermal Growth Factor Receptor
J. Biol. Chem. 2007 282: 21278-21284. First Published on June 1, 2007; doi:10.1074/jbc.M703725200 [Abstract] [Full Text] [PDF]

R. Benjamin Free, Lisa A. Hazelwood, David M. Cabrera, Heather N. Spalding, Yoon Namkung, Michele L. Rankin, and David R. Sibley: D₁ and D₂ Dopamine Receptor Expression Is Regulated by Direct Interaction with the Chaperone Protein Calnexin
J. Biol. Chem. 2007 282: 21285-21300. First Published on March 29, 2007; doi:10.1074/jbc.M701555200 [Abstract] [Full Text] [PDF]

Rohit Kohli, Xiaomin Pan, Padmini Malladi, Mark S. Wainwright, and Peter F. Whitington: Mitochondrial Reactive Oxygen Species Signal Hepatocyte Steatosis by Regulating the Phosphatidylinositol 3-Kinase Cell Survival Pathway
J. Biol. Chem. 2007 282: 21327-21336. First Published on May 31, 2007; doi:10.1074/jbc.M701759200 [Abstract] [Full Text] [PDF]

Nachman Mazurek, Yun Jie Sun, Kai-Feng Liu, Michael Z. Gilcrease, Wendy Schober, Pratima Nangia-Makker, Avraham Raz, and Robert S. Bresalier: Phosphorylated Galectin-3 Mediates Tumor Necrosis Factor-related Apoptosis-inducing Ligand Signaling by Regulating Phosphatase and Tensin Homologue Deleted on Chromosome 10 in Human Breast Carcinoma Cells
J. Biol. Chem. 2007 282: 21337-21348. First Published on April 9, 2007; doi:10.1074/jbc.M608810200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kelly N. Nobles, Ziqiang Guan, Kunhong Xiao, Terrence G. Oas, and Robert J. Lefkowitz: The Active Conformation of $beta$ -Arrestin1: DIRECT EVIDENCE FOR THE PHOSPHATE SENSOR IN THE N-DOMAIN AND CONFORMATIONAL DIFFERENCES IN THE ACTIVE STATES OF $beta$ -ARRESTINS1 AND -2
J. Biol. Chem. 2007 282: 21370-21381. First Published on May 18, 2007; doi:10.1074/jbc.M611483200 [Abstract] [Full Text] [PDF]

Heather R. Melowic, Robert V. Stahelin, Nichole R. Blatner, Wen Tian, Keitaro Hayashi, Amnon Altman, and Wonhwa Cho: Mechanism of Diacylglycerol-induced Membrane Targeting and Activation of Protein Kinase C ${theta}$
J. Biol. Chem. 2007 282: 21467-21476. First Published on June 4, 2007; doi:10.1074/jbc.M700119200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zhimin Peng, Li Peng, Yunxia Fan, Ebrahim Zandi, Howard G. Shertzer, and Ying Xia: A Critical Role for I ${kappa}$ B Kinase $beta$ in Metallothionein-1 Expression and Protection against Arsenic Toxicity
J. Biol. Chem. 2007 282: 21487-21496. First Published on May 25, 2007; doi:10.1074/jbc.M702510200 [Abstract] [Full Text] [PDF]

Patricia Kreis, Emmanuel Thévenot, Véronique Rousseau, Bernadett Boda, Dominique Muller, and Jean-Vianney Barnier: The p21-activated Kinase 3 Implicated in Mental Retardation Regulates Spine Morphogenesis through a Cdc42-dependent Pathway
J. Biol. Chem. 2007 282: 21497-21506. First Published on May 30, 2007; doi:10.1074/jbc.M703298200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nam Y. Lee and Gerard C. Blobe: The Interaction of Endoglin with $beta$ -Arrestin2 Regulates Transforming Growth Factor- $beta$ -mediated ERK Activation and Migration in Endothelial Cells
J. Biol. Chem. 2007 282: 21507-21517. First Published on May 31, 2007; doi:10.1074/jbc.M700176200 [Abstract] [Full Text] [PDF]

Elena Shumay, Jiangchuan Tao, Hsien-yu Wang, and Craig C. Malbon: Lysophosphatidic Acid Regulates Trafficking of $beta$ ₂-Adrenergic Receptors: THE G ${alpha}$ ₁₃/p115RhoGEF/JNK PATHWAY STIMULATES RECEPTOR INTERNALIZATION
J. Biol. Chem. 2007 282: 21529-21541. First Published on May 10, 2007; doi:10.1074/jbc.M701998200 [Abstract] [Full Text] [PDF]

Yiwei Li, Zhiwei Wang, Dejuan Kong, Shalini Murthy, Q. Ping Dou, Shijie Sheng, G. Prem Veer Reddy, and Fazlul H. Sarkar: Regulation of FOXO3a/ $beta$ -Catenin/GSK-3 $beta$ Signaling by 3,3'-Diindolylmethane Contributes to Inhibition of Cell Proliferation and Induction of Apoptosis in Prostate Cancer Cells
J. Biol. Chem. 2007 282: 21542-21550. First Published on May 23, 2007; doi:10.1074/jbc.M701978200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Additions and Corrections:

Mary Cloud B. Ammons, Daniel W. Siemsen, Laura K. Nelson-Overton, Mark T. Quinn, and Katherine A. Gauss: Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)- ${alpha}$ -responsive region of the NCF2 promoter regulates p67^phox expression and NADPH oxidase activity. VOLUME 282 (2007) PAGES 17941-17952
J. Biol. Chem. 2007 282: 21572. [Full Text] [PDF]