JBC -- Table of Contents (Feb 16 2007, 282, (7))

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Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Ribonuclease P and the Discovery of Catalytic RNA: the Work of Sidney Altman
Purification and Properties of a Specific Escherichia coli Ribonuclease which Cleaves a Tyrosine Transfer Ribonucleic Acid Precursor (Hugh D. Robertson, Sidney Altman, and John D. Smith J. Biol. Chem. 247, 5243-5251)
The recognition by RNase P of precursor tRNAs (MF Baer, RM Reilly, GM McCorkle, TY Hai, S Altman, and UL RajBhandary J. Biol. Chem. 263, 2344-2351)
J. Biol. Chem. 2007 282: e5. [Full Text]

Minireviews:

David C. Klein: Arylalkylamine N-Acetyltransferase: "the Timezyme"
J. Biol. Chem. 2007 282: 4233-4237. First Published on December 12, 2006; doi:10.1074/jbc.R600036200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Accelerated Publications:

Kazutaka Murayama, Mikako Shirouzu, Yoshihiro Kawasaki, Miyuki Kato-Murayama, Kyoko Hanawa-Suetsugu, Ayako Sakamoto, Yasuhiro Katsura, Atsushi Suenaga, Mitsutoshi Toyama, Takaho Terada, Makoto Taiji, Tetsu Akiyama, and Shigeyuki Yokoyama: Crystal Structure of the Rac Activator, Asef, Reveals Its Autoinhibitory Mechanism
J. Biol. Chem. 2007 282: 4238-4242. First Published on December 26, 2006; doi:10.1074/jbc.C600234200 [Abstract] [Full Text] [PDF] [Supplemental Data]

DNA: Replication, Repair, and Recombination:

Saori Mori and Katsuhiko Shirahige: Perturbation of the Activity of Replication Origin by Meiosis-specific Transcription
J. Biol. Chem. 2007 282: 4447-4452. First Published on December 14, 2006; doi:10.1074/jbc.M609671200 [Abstract] [Full Text] [PDF]

Erik Schleicher, Kenichi Hitomi, Christopher W. M. Kay, Elizabeth D. Getzoff, Takeshi Todo, and Stefan Weber: Electron Nuclear Double Resonance Differentiates Complementary Roles for Active Site Histidines in (6-4) Photolyase
J. Biol. Chem. 2007 282: 4738-4747. First Published on December 12, 2006; doi:10.1074/jbc.M604734200 [Abstract] [Full Text] [PDF]

Jae-Ho Shin, Thomas J. Santangelo, Yunwei Xie, John N. Reeve, and Zvi Kelman: Archaeal Minichromosome Maintenance (MCM) Helicase Can Unwind DNA Bound by Archaeal Histones and Transcription Factors
J. Biol. Chem. 2007 282: 4908-4915. First Published on December 9, 2006; doi:10.1074/jbc.M606847200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Delphine Cougot, Yuanfei Wu, Stefano Cairo, Julie Caramel, Claire-Angélique Renard, Laurence Lévy, Marie Annick Buendia, and Christine Neuveut: The Hepatitis B Virus X Protein Functionally Interacts with CREB-binding Protein/p300 in the Regulation of CREB-mediated Transcription
J. Biol. Chem. 2007 282: 4277-4287. First Published on December 11, 2006; doi:10.1074/jbc.M606774200 [Abstract] [Full Text] [PDF]

Nicolas Venteclef and Philippe Delerive: Interleukin-1 Receptor Antagonist Induction as an Additional Mechanism for Liver Receptor Homolog-1 to Negatively Regulate the Hepatic Acute Phase Response
J. Biol. Chem. 2007 282: 4393-4399. First Published on December 11, 2006; doi:10.1074/jbc.M608993200 [Abstract] [Full Text] [PDF]

Barbara A. Burkhart, Sarah B. Kennett, and Trevor K. Archer: Osmotic Stress-dependent Repression Is Mediated by Histone H3 Phosphorylation and Chromatin Structure
J. Biol. Chem. 2007 282: 4400-4407. First Published on December 11, 2006; doi:10.1074/jbc.M609041200 [Abstract] [Full Text] [PDF]

Cicerone Tudor, Jérôme N. Feige, Harikishore Pingali, Vidya Bhushan Lohray, Walter Wahli, Béatrice Desvergne, Yves Engelborghs, and Laurent Gelman: Association with Coregulators Is the Major Determinant Governing Peroxisome Proliferator-activated Receptor Mobility in Living Cells
J. Biol. Chem. 2007 282: 4417-4426. First Published on December 12, 2006; doi:10.1074/jbc.M608172200 [Abstract] [Full Text] [PDF]

Somdutta Roy and Martin Tenniswood: Site-specific Acetylation of p53 Directs Selective Transcription Complex Assembly
J. Biol. Chem. 2007 282: 4765-4771. First Published on November 22, 2006; doi:10.1074/jbc.M609588200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sarah A. Boswell, Pat P. Ongusaha, Paul Nghiem, and Sam W. Lee: The Protective Role of a Small GTPase RhoE against UVB-induced DNA Damage in Keratinocytes
J. Biol. Chem. 2007 282: 4850-4858. First Published on December 14, 2006; doi:10.1074/jbc.M610532200 [Abstract] [Full Text] [PDF]

Yiguo Shen, Gena Lee, Youngshik Choe, J. Susie Zoltewicz, and Andrew S. Peterson: Functional Architecture of Atrophins
J. Biol. Chem. 2007 282: 5037-5044. First Published on December 6, 2006; doi:10.1074/jbc.M610274200 [Abstract] [Full Text] [PDF]

Stephan Ryser, Toshitsugu Fujita, Silvia Tortola, Isabelle Piuz, and Werner Schlegel: The Rate of c-fos Transcription in Vivo Is Continuously Regulated at the Level of Elongation by Dynamic Stimulus-coupled Recruitment of Positive Transcription Elongation Factor b
J. Biol. Chem. 2007 282: 5075-5084. First Published on December 12, 2006; doi:10.1074/jbc.M607847200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Structure, Metabolism, and Catalysis:

Catherine Cifuentes-Rojas, Paula Pavia, Alfredo Hernandez, Daniel Osterwisch, Concepcion Puerta, and Jorge Cruz-Reyes: Substrate Determinants for RNA Editing and Editing Complex Interactions at a Site for Full-round U Insertion
J. Biol. Chem. 2007 282: 4265-4276. First Published on December 7, 2006; doi:10.1074/jbc.M605554200 [Abstract] [Full Text] [PDF]

Stéphanie Larose, Nancy Laterreur, Ghada Ghazal, Jules Gagnon, Raymund J. Wellinger, and Sherif Abou Elela: RNase III-dependent Regulation of Yeast Telomerase
J. Biol. Chem. 2007 282: 4373-4381. First Published on December 11, 2006; doi:10.1074/jbc.M607145200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data]

Barbara Fries, Jochen Heukeshoven, Ilona Hauber, Cordula Grüttner, Carol Stocking, Ralph H. Kehlenbach, Joachim Hauber, and Jan Chemnitz: Analysis of Nucleocytoplasmic Trafficking of the HuR Ligand APRIL and Its Influence on CD83 Expression
J. Biol. Chem. 2007 282: 4504-4515. First Published on December 18, 2006; doi:10.1074/jbc.M608849200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Karl P. Nightingale, Susanne Gendreizig, Darren A. White, Charlotte Bradbury, Florian Hollfelder, and Bryan M. Turner: Cross-talk between Histone Modifications in Response to Histone Deacetylase Inhibitors: MLL4 LINKS HISTONE H3 ACETYLATION AND HISTONE H3K4 METHYLATION
J. Biol. Chem. 2007 282: 4408-4416. First Published on December 13, 2006; doi:10.1074/jbc.M606773200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tadahiro Shimazu, Sueharu Horinouchi, and Minoru Yoshida: Multiple Histone Deacetylases and the CREB-binding Protein Regulate Pre-mRNA 3'-End Processing
J. Biol. Chem. 2007 282: 4470-4478. First Published on December 17, 2006; doi:10.1074/jbc.M609745200 [Abstract] [Full Text] [PDF]

Zhiyong Ye and Yunn-Hwen Gan: Flagellin Contamination of Recombinant Heat Shock Protein 70 Is Responsible for Its Activity on T Cells
J. Biol. Chem. 2007 282: 4479-4484. First Published on December 18, 2006; doi:10.1074/jbc.M606802200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Livia Casciola-Rosen, Margarita Garcia-Calvo, Herbert G. Bull, Joseph W. Becker, Tonie Hines, Nancy A. Thornberry, and Antony Rosen: Mouse and Human Granzyme B Have Distinct Tetrapeptide Specificities and Abilities to Recruit the Bid Pathway
J. Biol. Chem. 2007 282: 4545-4552. First Published on December 19, 2006; doi:10.1074/jbc.M606564200 [Abstract] [Full Text] [PDF]

Kayo Koide, Saki Maegawa, Koreaki Ito, and Yoshinori Akiyama: Environment of the Active Site Region of RseP, an Escherichia coli Regulated Intramembrane Proteolysis Protease, Assessed by Site-directed Cysteine Alkylation
J. Biol. Chem. 2007 282: 4553-4560. First Published on December 19, 2006; doi:10.1074/jbc.M607339200 [Abstract] [Full Text] [PDF] [Supplemental Data]

James X. Du, C. Chris Yun, Agnieszka Bialkowska, and Vincent W. Yang: Protein Inhibitor of Activated STAT1 Interacts with and Up-regulates Activities of the Pro-proliferative Transcription Factor Krüppel-like Factor 5
J. Biol. Chem. 2007 282: 4782-4793. First Published on December 18, 2006; doi:10.1074/jbc.M603413200 [Abstract] [Full Text] [PDF]

Ying Wu, Daniel J. Termine, Matthew T. Swulius, Kelley W. Moremen, and Richard N. Sifers: Human Endoplasmic Reticulum Mannosidase I Is Subject to Regulated Proteolysis
J. Biol. Chem. 2007 282: 4841-4849. First Published on December 13, 2006; doi:10.1074/jbc.M607156200 [Abstract] [Full Text] [PDF]

Xuchu Que, Juan C. Engel, David Ferguson, Annette Wunderlich, Stanislas Tomavo, and Sharon L. Reed: Cathepsin Cs Are Key for the Intracellular Survival of the Protozoan Parasite, Toxoplasma gondii
J. Biol. Chem. 2007 282: 4994-5003. First Published on December 12, 2006; doi:10.1074/jbc.M606764200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Monica L. Friedrich, Meng Cui, Jeniffer B. Hernandez, Brian M. Weist, Hilde-Marie Andersen, Xiaowu Zhang, Lan Huang, and Craig M. Walsh: Modulation of DRAK2 Autophosphorylation by Antigen Receptor Signaling in Primary Lymphocytes
J. Biol. Chem. 2007 282: 4573-4584. First Published on December 20, 2006; doi:10.1074/jbc.M606675200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Marc E. Lenburg, Anupama Sinha, Douglas V. Faller, and Gerald V. Denis: Tumor-specific and Proliferation-specific Gene Expression Typifies Murine Transgenic B Cell Lymphomagenesis
J. Biol. Chem. 2007 282: 4803-4811. First Published on December 13, 2006; doi:10.1074/jbc.M605870200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Vivienne Fardeau, Gaëlle Lelandais, Andrew Oldfield, Hélène Salin, Sophie Lemoine, Mathilde Garcia, Véronique Tanty, Stéphane Le Crom, Claude Jacq, and Frédéric Devaux: The Central Role of PDR1 in the Foundation of Yeast Drug Resistance
J. Biol. Chem. 2007 282: 5063-5074. First Published on December 11, 2006; doi:10.1074/jbc.M610197200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data]

Protein Structure and Folding:

Tia Estey, Miriam Cantore, Philip A. Weston, John F. Carpenter, J. Mark Petrash, and Vasilis Vasiliou: Mechanisms Involved in the Protection of UV-induced Protein Inactivation by the Corneal Crystallin ALDH3A1
J. Biol. Chem. 2007 282: 4382-4392. First Published on December 11, 2006; doi:10.1074/jbc.M607546200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anat L. Bonshtien, Celeste Weiss, Anna Vitlin, Adina Niv, George H. Lorimer, and Abdussalam Azem: Significance of the N-terminal Domain for the Function of Chloroplast cpn20 Chaperonin
J. Biol. Chem. 2007 282: 4463-4469. First Published on December 17, 2006; doi:10.1074/jbc.M606433200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Huansheng Gong, Anne Murphy, Christopher R. McMaster, and David M. Byers: Neutralization of Acidic Residues in Helix II Stabilizes the Folded Conformation of Acyl Carrier Protein and Variably Alters Its Function with Different Enzymes
J. Biol. Chem. 2007 282: 4494-4503. First Published on December 18, 2006; doi:10.1074/jbc.M608234200 [Abstract] [Full Text] [PDF]

Yu-Chie Huang, Yu-Min Lin, Ting-Wei Chang, Shih-Jung Wu, Yan-Shin Lee, Margaret Dah-Tsyr Chang, Chinpan Chen, Shih-Hsiung Wu, and You-Di Liao: The Flexible and Clustered Lysine Residues of Human Ribonuclease 7 Are Critical for Membrane Permeability and Antimicrobial Activity
J. Biol. Chem. 2007 282: 4626-4633. First Published on December 6, 2006; doi:10.1074/jbc.M607321200 [Abstract] [Full Text] [PDF]

Gerardo Corzo, Jennifer K. Sabo, Frank Bosmans, Bert Billen, Elba Villegas, Jan Tytgat, and Raymond S. Norton: Solution Structure and Alanine Scan of a Spider Toxin That Affects the Activation of Mammalian Voltage-gated Sodium Channels
J. Biol. Chem. 2007 282: 4643-4652. First Published on December 5, 2006; doi:10.1074/jbc.M605403200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Krishan Gopal Thakur, Anagha Madhusudan Joshi, and B. Gopal: Structural and Biophysical Studies on Two Promoter Recognition Domains of the Extra-cytoplasmic Function ${sigma}$ Factor ${sigma}$ ^C from Mycobacterium tuberculosis
J. Biol. Chem. 2007 282: 4711-4718. First Published on December 4, 2006; doi:10.1074/jbc.M606283200 [Abstract] [Full Text] [PDF]

Theresa N. Operaña and Robert H. Tukey: Oligomerization of the UDP-glucuronosyltransferase 1A Proteins: HOMO- AND HETERODIMERIZATION ANALYSIS BY FLUORESCENCE RESONANCE ENERGY TRANSFER AND CO-IMMUNOPRECIPITATION
J. Biol. Chem. 2007 282: 4821-4829. First Published on December 19, 2006; doi:10.1074/jbc.M609417200 [Abstract] [Full Text] [PDF]

Andrey Galkin, Liudmila Kulakova, Eugene Melamud, Ling Li, Chun Wu, Patrick Mariano, Debra Dunaway-Mariano, Theodore E. Nash, and Osnat Herzberg: Characterization, Kinetics, and Crystal Structures of Fructose-1,6-bisphosphate Aldolase from the Human Parasite, Giardia lamblia
J. Biol. Chem. 2007 282: 4859-4867. First Published on December 13, 2006; doi:10.1074/jbc.M609534200 [Abstract] [Full Text] [PDF]

Yiping Jia, Paul W. Buehler, Robert A. Boykins, Richard M. Venable, and Abdu I. Alayash: Structural Basis of Peroxide-mediated Changes in Human Hemoglobin: A NOVEL OXIDATIVE PATHWAY
J. Biol. Chem. 2007 282: 4894-4907. First Published on December 17, 2006; doi:10.1074/jbc.M609955200 [Abstract] [Full Text] [PDF]

Yukiko Hori, Tadafumi Hashimoto, Yosuke Wakutani, Katsuya Urakami, Kenji Nakashima, Margaret M. Condron, Satoshi Tsubuki, Takaomi C. Saido, David B. Teplow, and Takeshi Iwatsubo: The Tottori (D7N) and English (H6R) Familial Alzheimer Disease Mutations Accelerate A $beta$ Fibril Formation without Increasing Protofibril Formation
J. Biol. Chem. 2007 282: 4916-4923. First Published on December 14, 2006; doi:10.1074/jbc.M608220200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pierre Montaville, Christine Schlicker, Andrei Leonov, Markus Zweckstetter, George M. Sheldrick, and Stefan Becker: The C2A-C2B Linker Defines the High Affinity Ca²⁺ Binding Mode of Rabphilin-3A
J. Biol. Chem. 2007 282: 5015-5025. First Published on December 13, 2006; doi:10.1074/jbc.M606746200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Carol A. Chrestensen, Jacquelyn K. Shuman, Andrew Eschenroeder, Mark Worthington, Hermann Gram, and Thomas W. Sturgill: MNK1 and MNK2 Regulation in HER2-overexpressing Breast Cancer Lines
J. Biol. Chem. 2007 282: 4243-4252. First Published on November 27, 2006; doi:10.1074/jbc.M607368200 [Abstract] [Full Text] [PDF]

Alan R. Penheiter, Michelle Bogoger, Patricia A. Ellison, Barbara Oswald, William J. Perkins, Keith A. Jones, and Christine R. Cremo: H₂O₂-induced Kinetic and Chemical Modifications of Smooth Muscle Myosin: CORRELATION TO EFFECTS OF H₂O₂ ON AIRWAY SMOOTH MUSCLE
J. Biol. Chem. 2007 282: 4336-4344. First Published on November 22, 2006; doi:10.1074/jbc.M609499200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Markus Liebscher, Günther Jahreis, Christian Lücke, Susanne Grabley, Satish Raina, and Cordelia Schiene-Fischer: Fatty Acyl Benzamido Antibacterials Based on Inhibition of DnaK-catalyzed Protein Folding
J. Biol. Chem. 2007 282: 4437-4446. First Published on December 14, 2006; doi:10.1074/jbc.M607667200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Peppi Koivunen, Maija Hirsilä, Anne M. Remes, Ilmo E. Hassinen, Kari I. Kivirikko, and Johanna Myllyharju: Inhibition of Hypoxia-inducible Factor (HIF) Hydroxylases by Citric Acid Cycle Intermediates: POSSIBLE LINKS BETWEEN CELL METABOLISM AND STABILIZATION OF HIF
J. Biol. Chem. 2007 282: 4524-4532. First Published on December 19, 2006; doi:10.1074/jbc.M610415200 [Abstract] [Full Text] [PDF]

Tsui-Fen Chou and Carston R. Wagner: Lysyl-tRNA Synthetase-generated Lysyl-Adenylate Is a Substrate for Histidine Triad Nucleotide Binding Proteins
J. Biol. Chem. 2007 282: 4719-4727. First Published on December 8, 2006; doi:10.1074/jbc.M610530200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Maria V. Barbolina, Brian P. Adley, Edgardo V. Ariztia, Yueying Liu, and M. Sharon Stack: Microenvironmental Regulation of Membrane Type 1 Matrix Metalloproteinase Activity in Ovarian Carcinoma Cells via Collagen-induced EGR1 Expression
J. Biol. Chem. 2007 282: 4924-4931. First Published on December 11, 2006; doi:10.1074/jbc.M608428200 [Abstract] [Full Text] [PDF]

Laura I. de Eugenio, Pedro García, José M. Luengo, Jesús M. Sanz, Julio San Román, José Luis García, and María A. Prieto: Biochemical Evidence That phaZ Gene Encodes a Specific Intracellular Medium Chain Length Polyhydroxyalkanoate Depolymerase in Pseudomonas putida KT2442: CHARACTERIZATION OF A PARADIGMATIC ENZYME
J. Biol. Chem. 2007 282: 4951-4962. First Published on December 14, 2006; doi:10.1074/jbc.M608119200 [Abstract] [Full Text] [PDF]

James C. Burnett, Gordon Ruthel, Christian M. Stegmann, Rekha G. Panchal, Tam L. Nguyen, Ann R. Hermone, Robert G. Stafford, Douglas J. Lane, Tara A. Kenny, Connor F. McGrath, Peter Wipf, Andrea M. Stahl, James J. Schmidt, Rick Gussio, Axel T. Brunger, and Sina Bavari: Inhibition of Metalloprotease Botulinum Serotype A from a Pseudo-peptide Binding Mode to a Small Molecule That Is Active in Primary Neurons
J. Biol. Chem. 2007 282: 5004-5014. First Published on November 8, 2006; doi:10.1074/jbc.M608166200 [Abstract] [Full Text] [PDF] [Supplemnetal Data]

Sergei G. Kruglik, Jean-Christophe Lambry, Simona Cianetti, Jean-Louis Martin, Robert R. Eady, Colin R. Andrew, and Michel Negrerie: Molecular Basis for Nitric Oxide Dynamics and Affinity with Alcaligenes xylosoxidans Cytochrome $c$
J. Biol. Chem. 2007 282: 5053-5062. First Published on December 11, 2006; doi:10.1074/jbc.M604327200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolism and Bioenergetics:

Jennifer L. Stephens, Soo Hee Lee, Kimberly S. Paul, and Paul T. Englund: Mitochondrial Fatty Acid Synthesis in Trypanosoma brucei
J. Biol. Chem. 2007 282: 4427-4436. First Published on December 12, 2006; doi:10.1074/jbc.M609037200 [Abstract] [Full Text] [PDF]

Sunghee Cho, Hazel H. Szeto, Eunhee Kim, Hyunjoo Kim, Aaron T. Tolhurst, and John T. Pinto: A Novel Cell-permeable Antioxidant Peptide, SS31, Attenuates Ischemic Brain Injury by Down-regulating CD36
J. Biol. Chem. 2007 282: 4634-4642. First Published on December 18, 2006; doi:10.1074/jbc.M609388200 [Abstract] [Full Text] [PDF]

Leanne A. Pearson, Kevin D. Barrow, and Brett A. Neilan: Characterization of the 2-Hydroxy-acid Dehydrogenase McyI, Encoded within the Microcystin Biosynthesis Gene Cluster of Microcystis aeruginosa PCC7806
J. Biol. Chem. 2007 282: 4681-4692. First Published on December 1, 2006; doi:10.1074/jbc.M606986200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data]

Marlyse A. Debrincat, Jian-Guo Zhang, Tracy A. Willson, John Silke, Lisa M. Connolly, Richard J. Simpson, Warren S. Alexander, Nicos A. Nicola, Benjamin T. Kile, and Douglas J. Hilton: Ankyrin Repeat and Suppressors of Cytokine Signaling Box Protein Asb-9 Targets Creatine Kinase B for Degradation
J. Biol. Chem. 2007 282: 4728-4737. First Published on December 5, 2006; doi:10.1074/jbc.M609164200 [Abstract] [Full Text] [PDF]

Yan Xiong, Qu Fan Collins, Jie An, Edgar Lupo, Jr., Hui-Yu Liu, Delong Liu, Jacques Robidoux, Zhenqi Liu, and Wenhong Cao: p38 Mitogen-activated Protein Kinase Plays an Inhibitory Role in Hepatic Lipogenesis
J. Biol. Chem. 2007 282: 4975-4982. First Published on December 17, 2006; doi:10.1074/jbc.M606742200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Raju V. V. Tatituri, Petr A. Illarionov, Lynn G. Dover, Jerome Nigou, Martine Gilleron, Paul Hitchen, Karin Krumbach, Howard R. Morris, Neil Spencer, Anne Dell, Lothar Eggeling, and Gurdyal S. Besra: Inactivation of Corynebacterium glutamicum NCgl0452 and the Role of MgtA in the Biosynthesis of a Novel Mannosylated Glycolipid Involved in Lipomannan Biosynthesis
J. Biol. Chem. 2007 282: 4561-4572. First Published on December 19, 2006; doi:10.1074/jbc.M608695200 [Abstract] [Full Text] [PDF]

Dooyoung Lee, Joanne B. Schultz, Philip A. Knauf, and Michael R. King: Mechanical Shedding of L-selectin from the Neutrophil Surface during Rolling on Sialyl Lewis x under Flow
J. Biol. Chem. 2007 282: 4812-4820. First Published on December 15, 2006; doi:10.1074/jbc.M609994200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Zhiqiang Pan, Agnes M. Rimando, Scott R. Baerson, Mark Fishbein, and Stephen O. Duke: Functional Characterization of Desaturases Involved in the Formation of the Terminal Double Bond of an Unusual 16:3 ${Delta}$ ^{9, 12, 15} Fatty Acid Isolated from Sorghum bicolor Root Hairs
J. Biol. Chem. 2007 282: 4326-4335. First Published on December 18, 2006; doi:10.1074/jbc.M606343200 [Abstract] [Full Text] [PDF]

René L. Jacobs, Susanne Lingrell, Jason R. B. Dyck, and Dennis E. Vance: Inhibition of Hepatic Phosphatidylcholine Synthesis by 5-Aminoimidazole-4-carboxamide-1- $beta$ -4-ribofuranoside Is Independent of AMP-activated Protein Kinase Activation
J. Biol. Chem. 2007 282: 4516-4523. First Published on December 19, 2006; doi:10.1074/jbc.M605702200 [Abstract] [Full Text] [PDF]

Markus Fritz, Heiko Lokstein, Dieter Hackenberg, Ruth Welti, Mary Roth, Ulrich Zähringer, Martin Fulda, Wiebke Hellmeyer, Claudia Ott, Frank P. Wolter, and Ernst Heinz: Channeling of Eukaryotic Diacylglycerol into the Biosynthesis of Plastidial Phosphatidylglycerol
J. Biol. Chem. 2007 282: 4613-4625. First Published on December 11, 2006; doi:10.1074/jbc.M606295200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kevin Mouzat, Magali Prod'Homme, David H. Volle, Benoit Sion, Pierre Déchelotte, Karine Gauthier, Jean-Marc Vanacker, and Jean-Marc A. Lobaccaro: Oxysterol Nuclear Receptor LXR $beta$ Regulates Cholesterol Homeostasis and Contractile Function in Mouse Uterus
J. Biol. Chem. 2007 282: 4693-4701. First Published on December 13, 2006; doi:10.1074/jbc.M606718200 [Abstract] [Full Text] [PDF]

Gregory D. Fairn, Kendra MacDonald, and Christopher R. McMaster: A Chemogenomic Screen in Saccharomyces cerevisiae Uncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway
J. Biol. Chem. 2007 282: 4868-4874. First Published on December 12, 2006; doi:10.1074/jbc.M610575200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Isabella Sarto-Jackson, Roman Furtmueller, Margot Ernst, Sigismund Huck, and Werner Sieghart: Spontaneous Cross-link of Mutated ${alpha}$ 1 Subunits during GABA_A Receptor Assembly
J. Biol. Chem. 2007 282: 4354-4363. First Published on December 4, 2006; doi:10.1074/jbc.M609676200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Frank Visser, Valeria Valsecchi, Lucio Annunziato, and Jonathan Lytton: Analysis of Ion Interactions with the K⁺ -dependent Na⁺/Ca⁺ Exchangers NCKX2, NCKX3, and NCKX4: IDENTIFICATION OF THR-551 AS A KEY RESIDUE IN DEFINING THE APPARENT K⁺ AFFINITY OF NCKX2
J. Biol. Chem. 2007 282: 4453-4462. First Published on December 15, 2006; doi:10.1074/jbc.M610582200 [Abstract] [Full Text] [PDF]

Wei Wang, Karen Bernard, Ge Li, and Kevin L. Kirk: Curcumin Opens Cystic Fibrosis Transmembrane Conductance Regulator Channels by a Novel Mechanism That Requires neither ATP Binding nor Dimerization of the Nucleotide-binding Domains
J. Biol. Chem. 2007 282: 4533-4544. First Published on December 18, 2006; doi:10.1074/jbc.M609942200 [Abstract] [Full Text] [PDF]

Lucia B. Jilaveanu and Donald B. Oliver: In Vivo Membrane Topology of Escherichia coli SecA ATPase Reveals Extensive Periplasmic Exposure of Multiple Functionally Important Domains Clustering on One Face of SecA
J. Biol. Chem. 2007 282: 4661-4668. First Published on December 13, 2006; doi:10.1074/jbc.M610828200 [Abstract] [Full Text] [PDF]

Juan Rong, Shihua Li, Guoqing Sheng, Meng Wu, Brian Coblitz, Min Li, Haian Fu, and Xiao-Jiang Li: 14-3-3 Protein Interacts with Huntingtin-associated Protein 1 and Regulates Its Trafficking
J. Biol. Chem. 2007 282: 4748-4756. First Published on December 13, 2006; doi:10.1074/jbc.M609057200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shane R. Cunha, Naina Bhasin, and Peter J. Mohler: Targeting and Stability of Na/Ca Exchanger 1 in Cardiomyocytes Requires Direct Interaction with the Membrane Adaptor Ankyrin-B
J. Biol. Chem. 2007 282: 4875-4883. First Published on December 18, 2006; doi:10.1074/jbc.M607096200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sameer Mohammad, Giovanna Baldini, Susana Granell, Paola Narducci, Alberto M. Martelli, and Giulia Baldini: Constitutive Traffic of Melanocortin-4 Receptor in Neuro2A Cells and Immortalized Hypothalamic Neurons
J. Biol. Chem. 2007 282: 4963-4974. First Published on December 12, 2006; doi:10.1074/jbc.M608283200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Mita Gupta, Deborah Trott, and Andrew C. G. Porter: Rescue of a Human Cell Line from Endogenous Cdk1 Depletion by Cdk1 Lacking Inhibitory Phosphorylation Sites
J. Biol. Chem. 2007 282: 4301-4309. First Published on December 12, 2006; doi:10.1074/jbc.M607910200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data]

Zhongcong Xie, Yuanlin Dong, Uta Maeda, Weiming Xia, and Rudolph E. Tanzi: RNA Interference Silencing of the Adaptor Molecules ShcC and Fe65 Differentially Affect Amyloid Precursor Protein Processing and A $beta$ Generation
J. Biol. Chem. 2007 282: 4318-4325. First Published on December 14, 2006; doi:10.1074/jbc.M609293200 [Abstract] [Full Text] [PDF]

Noriyuki Yamamoto, Hideyuki Sawada, Yasuhiko Izumi, Toshiaki Kume, Hiroshi Katsuki, Shun Shimohama, and Akinori Akaike: Proteasome Inhibition Induces Glutathione Synthesis and Protects Cells from Oxidative Stress: RELEVANCE TO PARKINSON DISEASE
J. Biol. Chem. 2007 282: 4364-4372. First Published on December 8, 2006; doi:10.1074/jbc.M603712200 [Abstract] [Full Text] [PDF]

Wen-Xing Ding, Hong-Min Ni, Wentao Gao, Yi-Feng Hou, Melissa A. Melan, Xiaoyun Chen, Donna B. Stolz, Zhi-Ming Shao, and Xiao-Ming Yin: Differential Effects of Endoplasmic Reticulum Stress-induced Autophagy on Cell Survival
J. Biol. Chem. 2007 282: 4702-4710. First Published on November 29, 2006; doi:10.1074/jbc.M609267200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Mary Kaileh, Wim Vanden Berghe, Arne Heyerick, Julie Horion, Jacques Piette, Claude Libert, Denis De Keukeleire, Tamer Essawi, and Guy Haegeman: Withaferin A Strongly Elicits I ${kappa}$ B Kinase $beta$ Hyperphosphorylation Concomitant with Potent Inhibition of Its Kinase Activity
J. Biol. Chem. 2007 282: 4253-4264. First Published on December 6, 2006; doi:10.1074/jbc.M606728200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sasmita Mishra, Jyoti P. Mishra, and Ashok Kumar: Activation of JNK-dependent Pathway Is Required for HIV Viral Protein R-induced Apoptosis in Human Monocytic Cells: INVOLVEMENT OF ANTIAPOPTOTIC BCL2 AND c-IAP1 GENES
J. Biol. Chem. 2007 282: 4288-4300. First Published on December 11, 2006; doi:10.1074/jbc.M608307200 [Abstract] [Full Text] [PDF]

Chang-Wook Lee, Richard Rivera, Adrienne E. Dubin, and Jerold Chun: LPA₄/GPR23 Is a Lysophosphatidic Acid (LPA) Receptor Utilizing G_s-, G_q/G_i-mediated Calcium Signaling and G12/13-mediated Rho Activation
J. Biol. Chem. 2007 282: 4310-4317. First Published on December 13, 2006; doi:10.1074/jbc.M610826200 [Abstract] [Full Text] [PDF]

Beatrix Pollok-Kopp, Friederike Hüttenrauch, Stephanie Rethorn, and Martin Oppermann: Dynamics of Protein Kinase C-mediated Phosphorylation of the Complement C5a Receptor on Serine 334
J. Biol. Chem. 2007 282: 4345-4353. First Published on December 4, 2006; doi:10.1074/jbc.M601317200 [Abstract] [Full Text] [PDF]

Deifilia Ahuatzi, Alberto Riera, Rafael Peláez, Pilar Herrero, and Fernando Moreno: Hxk2 Regulates the Phosphorylation State of Mig1 and Therefore Its Nucleocytoplasmic Distribution
J. Biol. Chem. 2007 282: 4485-4493. First Published on December 18, 2006; doi:10.1074/jbc.M606854200 [Abstract] [Full Text] [PDF]

Julie Y. H. Chan, Hsiao-Lei Cheng, Jimmy L. J. Chou, Faith C. H. Li, Kuang-Yu Dai, Samuel H. H. Chan, and Alice Y. W. Chang: Heat Shock Protein 60 or 70 Activates Nitric-oxide Synthase (NOS) I- and Inhibits NOS II-associated Signaling and Depresses the Mitochondrial Apoptotic Cascade during Brain Stem Death
J. Biol. Chem. 2007 282: 4585-4600. First Published on December 5, 2006; doi:10.1074/jbc.M603394200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Constanze Blume, Peter M. Benz, Ulrich Walter, Joohun Ha, Bruce E. Kemp, and Thomas Renné: AMP-activated Protein Kinase Impairs Endothelial Actin Cytoskeleton Assembly by Phosphorylating Vasodilator-stimulated Phosphoprotein
J. Biol. Chem. 2007 282: 4601-4612. First Published on November 2, 2006; doi:10.1074/jbc.M608866200 [Abstract] [Full Text] [PDF]

Yi-Ling Lin, Willem J. S. de Villiers, Beth Garvy, Steven R. Post, Tim R. Nagy, Fayez F. Safadi, Marie Claude Faugere, Guodong Wang, Hartmut H. Malluche, and John P. Williams: The Effect of Class A Scavenger Receptor Deficiency in Bone
J. Biol. Chem. 2007 282: 4653-4660. First Published on December 13, 2006; doi:10.1074/jbc.M608552200 [Abstract] [Full Text] [PDF]

Anke Osterloh, Ulrich Kalinke, Siegfried Weiss, Bernhard Fleischer, and Minka Breloer: Synergistic and Differential Modulation of Immune Responses by Hsp60 and Lipopolysaccharide
J. Biol. Chem. 2007 282: 4669-4680. First Published on December 11, 2006; doi:10.1074/jbc.M608666200 [Abstract] [Full Text] [PDF]

Zhi Fang, Chul-Kyu Park, Hai Ying Li, Hyun Yeong Kim, Seong-Hae Park, Sung Jun Jung, Joong Soo Kim, Arnaud Monteil, Seog Bae Oh, and Richard J. Miller: Molecular Basis of Ca_v2.3 Calcium Channels in Rat Nociceptive Neurons
J. Biol. Chem. 2007 282: 4757-4764. First Published on December 4, 2006; doi:10.1074/jbc.M605248200 [Abstract] [Full Text] [PDF]

Garret R. Anderson, Arthur Semenov, Joseph H. Song, and Kirill A. Martemyanov: The Membrane Anchor R7BP Controls the Proteolytic Stability of the Striatal Specific RGS Protein, RGS9-2
J. Biol. Chem. 2007 282: 4772-4781. First Published on December 7, 2006; doi:10.1074/jbc.M610518200 [Abstract] [Full Text] [PDF] [Summary]

Céline Van Themsche, Isabelle Mathieu, Sophie Parent, and Eric Asselin: Transforming Growth Factor- $beta$ 3 Increases the Invasiveness of Endometrial Carcinoma Cells through Phosphatidylinositol 3-Kinase-dependent Up-regulation of X-linked Inhibitor of Apoptosis and Protein Kinase C-dependent Induction of Matrix Metalloproteinase-9
J. Biol. Chem. 2007 282: 4794-4802. First Published on December 6, 2006; doi:10.1074/jbc.M608497200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mélanie Sanchez, Karine Sauvé, Nathalie Picard, and André Tremblay: The Hormonal Response of Estrogen Receptor $beta$ Is Decreased by the Phosphatidylinositol 3-Kinase/Akt Pathway via a Phosphorylation-dependent Release of CREB-binding Protein
J. Biol. Chem. 2007 282: 4830-4840. First Published on December 12, 2006; doi:10.1074/jbc.M607908200 [Abstract] [Full Text] [PDF]

Laura Hagerty, Douglas H. Weitzel, Jenica Chambers, Christopher N. Fortner, Matthew H. Brush, David Loiselle, Hiroshi Hosoya, and Timothy A. J. Haystead: ROCK1 Phosphorylates and Activates Zipper-interacting Protein Kinase
J. Biol. Chem. 2007 282: 4884-4893. First Published on December 8, 2006; doi:10.1074/jbc.M609990200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Augusto Orlandi, Arianna Francesconi, Marcella Marcellini, Antonio Di Lascio, and Luigi Giusto Spagnoli: Propionyl-L-carnitine Reduces Proliferation and Potentiates Bax-related Apoptosis of Aortic Intimal Smooth Muscle Cells by Modulating Nuclear Factor- ${kappa}$ B Activity
J. Biol. Chem. 2007 282: 4932-4942. First Published on December 17, 2006; doi:10.1074/jbc.M606148200 [Abstract] [Full Text] [PDF]

Hongzhe Li, Xiaojian Wang, Nan Li, Jianming Qiu, Yuanyuan Zhang, and Xuetao Cao: hPEBP4 Resists TRAIL-induced Apoptosis of Human Prostate Cancer Cells by Activating Akt and Deactivating ERK1/2 Pathways
J. Biol. Chem. 2007 282: 4943-4950. First Published on December 18, 2006; doi:10.1074/jbc.M609494200 [Abstract] [Full Text] [PDF]

Nandini Ghosh-Choudhury, Chandi Charan Mandal, and Goutam Ghosh Choudhury: Statin-induced Ras Activation Integrates the Phosphatidylinositol 3-Kinase Signal to Akt and MAPK for Bone Morphogenetic Protein-2 Expression in Osteoblast Differentiation
J. Biol. Chem. 2007 282: 4983-4993. First Published on December 19, 2006; doi:10.1074/jbc.M606706200 [Abstract] [Full Text] [PDF]

Weidong Yong, Zuocheng Yang, Sumudra Periyasamy, Hanying Chen, Selcul Yucel, Wei Li, Leanne Y. Lin, Irene M. Wolf, Martin J. Cohn, Laurence S. Baskin, Edwin R. Sánchez, and Weinian Shou: Essential Role for Co-chaperone Fkbp52 but Not Fkbp51 in Androgen Receptor-mediated Signaling and Physiology
J. Biol. Chem. 2007 282: 5026-5036. First Published on December 1, 2006; doi:10.1074/jbc.M609360200 [Abstract] [Full Text] [PDF]

Santina Bruzzone, Giuliano Dodoni, Nina Kaludercic, Giovanna Basile, Enrico Millo, Antonio De Flora, Fabio Di Lisa, and Elena Zocchi: Mitochondrial Dysfunction Induced by a Cytotoxic Adenine Dinucleotide Produced by ADP-ribosyl Cyclases from cADPR
J. Biol. Chem. 2007 282: 5045-5052. First Published on December 8, 2006; doi:10.1074/jbc.M609802200 [Abstract] [Full Text] [PDF]

Lidia A. Gardner, Anjaparavanda P. Naren, and Suleiman W. Bahouth: Assembly of an SAP97-AKAP79-cAMP-dependent Protein Kinase Scaffold at the Type 1 PSD-95/DLG/ZO1 Motif of the Human $beta$ ₁-Adrenergic Receptor Generates a Receptosome Involved in Receptor Recycling and Networking
J. Biol. Chem. 2007 282: 5085-5099. First Published on December 14, 2006; doi:10.1074/jbc.M608871200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Emmanuelle Adam, Kristina K. Hansen, Olaya Astudillo Fernandez, Ludivine Coulon, Françoise Bex, Xavier Duhant, Erika Jaumotte, Morley D. Hollenberg, and Alain Jacquet: The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. VOLUME 281 (2006) PAGES 6910-6923
J. Biol. Chem. 2007 282: 5100. [Full Text] [PDF]