JBC -- Table of Contents (Mar 2 2007, 282, (9))

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Accelerated Publications:

Askar M. Akimzhanov, Xuexian O Yang, and Chen Dong: Chromatin Remodeling of Interleukin-17 (IL-17)-IL-17F Cytokine Gene Locus during Inflammatory Helper T Cell Differentiation
J. Biol. Chem. 2007 282: 5969-5972. First Published on January 11, 2007; doi:10.1074/jbc.C600322200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Lori S. Hart, David Ornelles, and Constantinos Koumenis: The Adenoviral E4orf6 Protein Induces Atypical Apoptosis in Response to DNA Damage
J. Biol. Chem. 2007 282: 6061-6067. First Published on December 15, 2006; doi:10.1074/jbc.M610405200 [Abstract] [Full Text] [PDF]

Lu Gao, Mini Balakrishnan, Bernard P. Roques, and Robert A. Bambara: Insights into the Multiple Roles of Pausing in HIV-1 Reverse Transcriptase-promoted Strand Transfers
J. Biol. Chem. 2007 282: 6222-6231. First Published on January 3, 2007; doi:10.1074/jbc.M610056200 [Abstract] [Full Text] [PDF]

Benjamin P. C. Chen, Naoya Uematsu, Junya Kobayashi, Yaniv Lerenthal, Andrea Krempler, Hirohiko Yajima, Markus Löbrich, Yosef Shiloh, and David J. Chen: Ataxia Telangiectasia Mutated (ATM) Is Essential for DNA-PKcs Phosphorylations at the Thr-2609 Cluster upon DNA Double Strand Break
J. Biol. Chem. 2007 282: 6582-6587. First Published on December 21, 2006; doi:10.1074/jbc.M611605200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Kazuhiro Eto, Varinderpal Kaur, and Melissa K. Thomas: Regulation of Pancreas Duodenum Homeobox-1 Expression by Early Growth Response-1
J. Biol. Chem. 2007 282: 5973-5983. First Published on December 6, 2006; doi:10.1074/jbc.M607288200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pawel Wlodarski, Qian Zhang, Xiaobin Liu, Monika Kasprzycka, Michal Marzec, and Mariusz A. Wasik: PU.1 Activates Transcription of SHP-1 Gene in Hematopoietic Cells
J. Biol. Chem. 2007 282: 6316-6323. First Published on January 11, 2007; doi:10.1074/jbc.M607526200 [Abstract] [Full Text] [PDF]

Richard Dahl, Sangeeta R. Iyer, Kristin S. Owens, Dorothy D. Cuylear, and M. Celeste Simon: The Transcriptional Repressor GFI-1 Antagonizes PU.1 Activity through Protein-Protein Interaction
J. Biol. Chem. 2007 282: 6473-6483. First Published on December 31, 2006; doi:10.1074/jbc.M607613200 [Abstract] [Full Text] [PDF]

Weiqi Huang, Elizabeth Horvath, and Elizabeth A. Eklund: PU.1, Interferon Regulatory Factor (IRF) 2, and the Interferon Consensus Sequence-binding Protein (ICSBP/IRF8) Cooperate to Activate NF1 Transcription in Differentiating Myeloid Cells
J. Biol. Chem. 2007 282: 6629-6643. First Published on January 2, 2007; doi:10.1074/jbc.M607760200 [Abstract] [Full Text] [PDF]

Daun B. Clizbe, Michelle L. Owens, Kimberly R. Masuda, Janis E. Shackelford, and Skaidrite K. Krisans: IDI2, a Second Isopentenyl Diphosphate Isomerase in Mammals
J. Biol. Chem. 2007 282: 6668-6676. First Published on January 3, 2007; doi:10.1074/jbc.M610922200 [Abstract] [Full Text] [PDF]

Shiou-Jeng Ong, Hong-Ming Hsu, Hsing-Wei Liu, Chien-Hsin Chu, and Jung-Hsiang Tai: Activation of Multifarious Transcription of an Adhesion Protein ap65-1 Gene by a Novel Myb2 Protein in the Protozoan Parasite Trichomonas vaginalis
J. Biol. Chem. 2007 282: 6716-6725. First Published on January 3, 2007; doi:10.1074/jbc.M610484200 [Abstract] [Full Text] [PDF]

Thomas D. Hock, Karen Liby, Marcienne M. Wright, Sean McConnell, Marina Schorpp-Kistner, Thomas M. Ryan, and Anupam Agarwal: JunB and JunD Regulate Human Heme Oxygenase-1 Gene Expression in Renal Epithelial Cells
J. Biol. Chem. 2007 282: 6875-6886. First Published on January 3, 2007; doi:10.1074/jbc.M608456200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Reynald Gillet, Sukhjit Kaur, Wen Li, Marc Hallier, Brice Felden, and Joachim Frank: Scaffolding as an Organizing Principle in Trans-translation: THE ROLES OF SMALL PROTEIN B AND RIBOSOMAL PROTEIN S1
J. Biol. Chem. 2007 282: 6356-6363. First Published on December 19, 2006; doi:10.1074/jbc.M609658200 [Abstract] [Full Text] [PDF]

Yan Ning, Tione Buranda, and Laurie G. Hudson: Activated Epidermal Growth Factor Receptor Induces Integrin ${alpha}$ 2 Internalization via Caveolae/Raft-dependent Endocytic Pathway
J. Biol. Chem. 2007 282: 6380-6387. First Published on December 19, 2006; doi:10.1074/jbc.M610915200 [Abstract] [Full Text] [PDF] [Supplemental Data]

T. N. C. Ramya, Krishanpal Karmodiya, Avadhesha Surolia, and Namita Surolia: 15-Deoxyspergualin Primarily Targets the Trafficking of Apicoplast Proteins in Plasmodium falciparum
J. Biol. Chem. 2007 282: 6388-6397. First Published on December 28, 2006; doi:10.1074/jbc.M610251200 [Abstract] [Full Text] [PDF]

Jeong Goo Lee and EunDuck P. Kay: Two Populations of p27 Use Differential Kinetics to Phosphorylate Ser-10 and Thr-187 via Phosphatidylinositol 3-Kinase in Response to Fibroblast Growth Factor-2 Stimulation
J. Biol. Chem. 2007 282: 6444-6454. First Published on January 5, 2007; doi:10.1074/jbc.M607808200 [Abstract] [Full Text] [PDF]

Madhusudan Dey, Chune Cao, Frank Sicheri, and Thomas E. Dever: Conserved Intermolecular Salt Bridge Required for Activation of Protein Kinases PKR, GCN2, and PERK
J. Biol. Chem. 2007 282: 6653-6660. First Published on January 3, 2007; doi:10.1074/jbc.M607897200 [Abstract] [Full Text] [PDF]

Renee Chosed, Diana R. Tomchick, Chad A. Brautigam, Sohini Mukherjee, Veera S. Negi, Mischa Machius, and Kim Orth: Structural Analysis of Xanthomonas XopD Provides Insights into Substrate Specificity of Ubiquitin-like Protein Proteases
J. Biol. Chem. 2007 282: 6773-6782. First Published on January 3, 2007; doi:10.1074/jbc.M608730200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genomics, Proteomics, and Bioinformatics:

Christopher J. Rivard, Lewis M. Brown, Nestor E. Almeida, Arvid B. Maunsbach, Kaarina Pihakaski-Maunsbach, Ana Andres-Hernando, Juan M. Capasso, and Tomas Berl: Expression of the Calcium-binding Protein S100A4 Is Markedly Up-regulated by Osmotic Stress and Is Involved in the Renal Osmoadaptive Response
J. Biol. Chem. 2007 282: 6644-6652. First Published on January 2, 2007; doi:10.1074/jbc.M609432200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Hongmin Li, Yiwei Zhao, Yi Guo, Zhong Li, Leslie Eisele, and Walid Mourad: Zinc Induces Dimerization of the Class II Major Histocompatibility Complex Molecule That Leads to Cooperative Binding to a Superantigen
J. Biol. Chem. 2007 282: 5991-6000. First Published on December 13, 2006; doi:10.1074/jbc.M608482200 [Abstract] [Full Text] [PDF]

Mario Rainaldi, Aaron P. Yamniuk, Tomohiko Murase, and Hans J. Vogel: Calcium-dependent and -independent Binding of Soybean Calmodulin Isoforms to the Calmodulin Binding Domain of Tobacco MAPK Phosphatase-1
J. Biol. Chem. 2007 282: 6031-6042. First Published on January 3, 2007; doi:10.1074/jbc.M608970200 [Abstract] [Full Text] [PDF]

Jing-He Huang, Lu Lu, Hong Lu, Xi Chen, Shibo Jiang, and Ying-Hua Chen: Identification of the HIV-1 gp41 Core-binding Motif in the Scaffolding Domain of Caveolin-1
J. Biol. Chem. 2007 282: 6143-6152. First Published on December 31, 2006; doi:10.1074/jbc.M607701200 [Abstract] [Full Text] [PDF]

Remo Gerber, Abdessamad Tahiri-Alaoui, P. J. Hore, and William James: Oligomerization of the Human Prion Protein Proceeds via a Molten Globule Intermediate
J. Biol. Chem. 2007 282: 6300-6307. First Published on January 8, 2007; doi:10.1074/jbc.M608926200 [Abstract] [Full Text] [PDF]

Luc Snyers, Sylvia Vlcek, Thomas Dechat, Darko Skegro, Barbara Korbei, Andreas Gajewski, Olga Mayans, Christian Schöfer, and Roland Foisner: Lamina-associated Polypeptide 2- ${alpha}$ Forms Homo-trimers via Its C Terminus, and Oligomerization Is Unaffected by a Disease-causing Mutation
J. Biol. Chem. 2007 282: 6308-6315. First Published on January 9, 2007; doi:10.1074/jbc.M605782200 [Abstract] [Full Text] [PDF]

Djemel Hamdane, Corinne Vasseur-Godbillon, Véronique Baudin-Creuza, Gaston Hui Bon Hoa, and Michael C. Marden: Reversible Hexacoordination of ${alpha}$ -Hemoglobin-stabilizing Protein (AHSP)/ ${alpha}$ -Hemoglobin Versus Pressure: EVIDENCE FOR PROTECTION OF THE ${alpha}$ -CHAINS BY THEIR CHAPERONE
J. Biol. Chem. 2007 282: 6398-6404. First Published on December 28, 2006; doi:10.1074/jbc.M610543200 [Abstract] [Full Text] [PDF]

Daisuke Horigome, Hiroyuki Satoh, Nobue Itoh, Katsuyoshi Mitsunaga, Isao Oonishi, Atsushi Nakagawa, and Akira Uchida: Structural Mechanism and Photoprotective Function of Water-soluble Chlorophyll-binding Protein
J. Biol. Chem. 2007 282: 6525-6531. First Published on December 14, 2006; doi:10.1074/jbc.M609458200 [Abstract] [Full Text] [PDF]

Zuzana Valnickova, Steen V. Petersen, Søren B. Nielsen, Daniel E. Otzen, and Jan J. Enghild: Heparin Binding Induces a Conformational Change in Pigment Epithelium-derived Factor
J. Biol. Chem. 2007 282: 6661-6667. First Published on January 2, 2007; doi:10.1074/jbc.M610471200 [Abstract] [Full Text] [PDF]

Ho Min Kim, Se Cheol Oh, Ki Jung Lim, Jun Kasamatsu, Jin Young Heo, Beom Seok Park, Hayyoung Lee, Ook Joon Yoo, Masanori Kasahara, and Jie-Oh Lee: Structural Diversity of the Hagfish Variable Lymphocyte Receptors
J. Biol. Chem. 2007 282: 6726-6732. First Published on December 27, 2006; doi:10.1074/jbc.M608471200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shang-Rung Wu, Lars Haag, Lena Hammar, Bomu Wu, Henrik Garoff, Li Xing, Kazuyoshi Murata, and R. Holland Cheng: The Dynamic Envelope of a Fusion Class II Virus: PREFUSION STAGES OF SEMLIKI FOREST VIRUS REVEALED BY ELECTRON CRYOMICROSCOPY
J. Biol. Chem. 2007 282: 6752-6762. First Published on December 27, 2006; doi:10.1074/jbc.M609125200 [Abstract] [Full Text] [PDF]

Minako Matsushita, Nobuo N. Suzuki, Keisuke Obara, Yuko Fujioka, Yoshinori Ohsumi, and Fuyuhiko Inagaki: Structure of Atg5·Atg16, a Complex Essential for Autophagy
J. Biol. Chem. 2007 282: 6763-6772. First Published on December 27, 2006; doi:10.1074/jbc.M609876200 [Abstract] [Full Text] [PDF]

Mitsunori Shiroishi, Kouhei Tsumoto, Yoshikazu Tanaka, Akiko Yokota, Takeshi Nakanishi, Hidemasa Kondo, and Izumi Kumagai: Structural Consequences of Mutations in Interfacial Tyr Residues of a Protein Antigen-Antibody Complex: THE CASE OF HyHEL-10-HEL
J. Biol. Chem. 2007 282: 6783-6791. First Published on December 12, 2006; doi:10.1074/jbc.M605197200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Meng-Huee Lee, Susan Atkinson, and Gillian Murphy: Identification of the Extracellular Matrix (ECM) Binding Motifs of Tissue Inhibitor of Metalloproteinases (TIMP)-3 and Effective Transfer to TIMP-1
J. Biol. Chem. 2007 282: 6887-6898. First Published on January 3, 2007; doi:10.1074/jbc.M610490200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Enrique Detarsio, Clarisa E. Alvarez, Mariana Saigo, Carlos S. Andreo, and María F. Drincovich: Identification of Domains Involved in Tetramerization and Malate Inhibition of Maize C₄-NADP-Malic Enzyme
J. Biol. Chem. 2007 282: 6053-6060. First Published on December 6, 2006; doi:10.1074/jbc.M609436200 [Abstract] [Full Text] [PDF]

Thomas Raschle, Duilio Arigoni, René Brunisholz, Helene Rechsteiner, Nikolaus Amrhein, and Teresa B. Fitzpatrick: Reaction Mechanism of Pyridoxal 5'-Phosphate Synthase: DETECTION OF AN ENZYME-BOUND CHROMOPHORIC INTERMEDIATE
J. Biol. Chem. 2007 282: 6098-6105. First Published on December 21, 2006; doi:10.1074/jbc.M610614200 [Abstract] [Full Text] [PDF]

Kalina Ranguelova, Stefania Girotto, Gary J. Gerfen, Shengwei Yu, Javier Suarez, Leonid Metlitsky, and Richard S. Magliozzo: Radical Sites in Mycobacterium tuberculosis KatG Identified Using Electron Paramagnetic Resonance Spectroscopy, the Three-dimensional Crystal Structure, and Electron Transfer Couplings
J. Biol. Chem. 2007 282: 6255-6264. First Published on January 4, 2007; doi:10.1074/jbc.M607309200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Frida Jacobson, Arthur Pistorius, Daniel Farkas, Willem De Grip, Örjan Hansson, Lennart Sjölin, and Richard Neutze: pH Dependence of Copper Geometry, Reduction Potential, and Nitrite Affinity in Nitrite Reductase
J. Biol. Chem. 2007 282: 6347-6355. First Published on December 5, 2006; doi:10.1074/jbc.M605746200 [Abstract] [Full Text] [PDF]

Jens Z. Pedersen, Francesca De Maria, Paola Turella, Giorgio Federici, Maurizio Mattei, Raffaele Fabrini, Kutayba F. Dawood, Mara Massimi, Anna Maria Caccuri, and Giorgio Ricci: Glutathione Transferases Sequester Toxic Dinitrosyl-Iron Complexes in Cells: A PROTECTION MECHANISM AGAINST EXCESS NITRIC OXIDE
J. Biol. Chem. 2007 282: 6364-6371. First Published on December 30, 2006; doi:10.1074/jbc.M609905200 [Abstract] [Full Text] [PDF]

Lorenzo Stella, Valentina Pallottini, Sandra Moreno, Silvia Leoni, Francesca De Maria, Paola Turella, Giorgio Federici, Raffaele Fabrini, Kutayba F. Dawood, Mario Lo Bello, Jens Z. Pedersen, and Giorgio Ricci: Electrostatic Association of Glutathione Transferase to the Nuclear Membrane: EVIDENCE OF AN ENZYME DEFENSE BARRIER AT THE NUCLEAR ENVELOPE
J. Biol. Chem. 2007 282: 6372-6379. First Published on December 30, 2006; doi:10.1074/jbc.M609906200 [Abstract] [Full Text] [PDF]

Brian J. N. Jepson, Sudesh Mohan, Thomas A. Clarke, Andrew J. Gates, Jeffrey A. Cole, Clive S. Butler, Julea N. Butt, Andrew M. Hemmings, and David J. Richardson: Spectropotentiometric and Structural Analysis of the Periplasmic Nitrate Reductase from Escherichia coli
J. Biol. Chem. 2007 282: 6425-6437. First Published on November 27, 2006; doi:10.1074/jbc.M607353200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jing Nie, Jing Pei, Malcolm Blumenthal, and Duanqing Pei: Complete Restoration of Cell Surface Activity of Transmembrane-truncated MT1-MMP by a Glycosylphosphatidylinositol Anchor: IMPLICATIONS FOR MT1-MMP-MEDIATED PROMMP2 ACTIVATION AND COLLAGENOLYSIS IN THREE-DIMENSIONS
J. Biol. Chem. 2007 282: 6438-6443. First Published on December 11, 2006; doi:10.1074/jbc.M607337200 [Abstract] [Full Text] [PDF]

Tim J. Winterburn, David M. Wyatt, Lowri H. Phylip, Daniel Bur, Rebecca J. Harrison, Colin Berry, and John Kay: Key Features Determining the Specificity of Aspartic Proteinase Inhibition by the Helix-forming IA₃ Polypeptide
J. Biol. Chem. 2007 282: 6508-6516. First Published on December 4, 2006; doi:10.1074/jbc.M610503200 [Abstract] [Full Text] [PDF]

Andrew W. Shaw, Vincent S. Pureza, Stephen G. Sligar, and James H. Morrissey: The Local Phospholipid Environment Modulates the Activation of Blood Clotting
J. Biol. Chem. 2007 282: 6556-6563. First Published on January 2, 2007; doi:10.1074/jbc.M607973200 [Abstract] [Full Text] [PDF]

Matthew L. Bentley, Helena Gaweska, Joseph M. Kielec, and Dewey G. McCafferty: Engineering the Substrate Specificity of Staphylococcus aureus Sortase A: THE $beta$ 6/ $beta$ 7 LOOP FROM SrtB CONFERS NPQTN RECOGNITION TO SrtA
J. Biol. Chem. 2007 282: 6571-6581. First Published on January 2, 2007; doi:10.1074/jbc.M610519200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kati Takaluoma, Marjo Hyry, Juha Lantto, Raija Sormunen, Ruud A. Bank, Kari I. Kivirikko, Johanna Myllyharju, and Raija Soininen: Tissue-specific Changes in the Hydroxylysine Content and Cross-links of Collagens and Alterations in Fibril Morphology in Lysyl Hydroxylase 1 Knock-out Mice
J. Biol. Chem. 2007 282: 6588-6596. First Published on December 29, 2006; doi:10.1074/jbc.M608830200 [Abstract] [Full Text] [PDF]

Tzanko I. Doukov, Hisashi Hemmi, Catherine L. Drennan, and Stephen W. Ragsdale: Structural and Kinetic Evidence for an Extended Hydrogen-bonding Network in Catalysis of Methyl Group Transfer: ROLE OF AN ACTIVE SITE ASPARAGINE RESIDUE IN ACTIVATION OF METHYL TRANSFER BY METHYLTRANSFERASES
J. Biol. Chem. 2007 282: 6609-6618. First Published on December 15, 2006; doi:10.1074/jbc.M609828200 [Abstract] [Full Text] [PDF] [Summary]

Seiya Watanabe, Masaki Yamada, Iwao Ohtsu, and Keisuke Makino: ${alpha}$ -Ketoglutaric Semialdehyde Dehydrogenase Isozymes Involved in Metabolic Pathways of D-Glucarate, D-Galactarate, and Hydroxy-L-proline: MOLECULAR AND METABOLIC CONVERGENT EVOLUTION
J. Biol. Chem. 2007 282: 6685-6695. First Published on January 3, 2007; doi:10.1074/jbc.M611057200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Emre M. Isin and F. Peter Guengerich: Multiple Sequential Steps Involved in the Binding of Inhibitors to Cytochrome P450 3A4
J. Biol. Chem. 2007 282: 6863-6874. First Published on January 2, 2007; doi:10.1074/jbc.M610346200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolism and Bioenergetics:

Tetsuo Yamashita, Eiko Nakamaru-Ogiso, Hideto Miyoshi, Akemi Matsuno-Yagi, and Takao Yagi: Roles of Bound Quinone in the Single Subunit NADH-Quinone Oxidoreductase (Ndi1) from Saccharomyces cerevisiae
J. Biol. Chem. 2007 282: 6012-6020. First Published on January 2, 2007; doi:10.1074/jbc.M610646200 [Abstract] [Full Text] [PDF]

Michael J. MacDonald: Synergistic Potent Insulin Release by Combinations of Weak Secretagogues in Pancreatic Islets and INS-1 Cells
J. Biol. Chem. 2007 282: 6043-6052. First Published on January 8, 2007; doi:10.1074/jbc.M606652200 [Abstract] [Full Text] [PDF]

Sung Gyun Kang, Alexandra L. Brown, and Jay H. Chung: Oxygen Tension Regulates the Stability of Insulin Receptor Substrate-1 (IRS-1) through Caspase-mediated Cleavage
J. Biol. Chem. 2007 282: 6090-6097. First Published on December 19, 2006; doi:10.1074/jbc.M610659200 [Abstract] [Full Text] [PDF]

Erin Easlon, Felicia Tsang, Ivanka Dilova, Chen Wang, Shu-Ping Lu, Craig Skinner, and Su-Ju Lin: The Dihydrolipoamide Acetyltransferase Is a Novel Metabolic Longevity Factor and Is Required for Calorie Restriction-mediated Life Span Extension
J. Biol. Chem. 2007 282: 6161-6171. First Published on January 2, 2007; doi:10.1074/jbc.M607661200 [Abstract] [Full Text] [PDF]

Hiromichi Minami, Emilyn Dubouzet, Kinuko Iwasa, and Fumihiko Sato: Functional Analysis of Norcoclaurine Synthase in Coptis japonica
J. Biol. Chem. 2007 282: 6274-6282. First Published on January 4, 2007; doi:10.1074/jbc.M608933200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yasuaki Kimura, Jean Alric, André Verméglio, Shinji Masuda, Yuuki Hagiwara, Katsumi Matsuura, Keizo Shimada, and Kenji V. P. Nagashima: A New Membrane-bound Cytochrome c Works as an Electron Donor to the Photosynthetic Reaction Center Complex in the Purple Bacterium, Rhodovulum sulfidophilum
J. Biol. Chem. 2007 282: 6463-6472. First Published on December 30, 2006; doi:10.1074/jbc.M604452200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Josef Voglmeir, Regina Voglauer, and Iain B. H. Wilson: XT-II, the Second Isoform of Human Peptide-O-xylosyltransferase, Displays Enzymatic Activity
J. Biol. Chem. 2007 282: 5984-5990. First Published on December 28, 2006; doi:10.1074/jbc.M608087200 [Abstract] [Full Text] [PDF]

Xiaoming Zhang, Raymond P. Boot-Handford, Julie Huxley-Jones, Lorna N. Forse, A. Paul Mould, David L. Robertson, LiLi, Matthews Athiyal, and Michael P. Sarras, Jr.: The Collagens of Hydra Provide Insight into the Evolution of Metazoan Extracellular Matrices
J. Biol. Chem. 2007 282: 6792-6802. First Published on January 3, 2007; doi:10.1074/jbc.M607528200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Nozomu Okino and Makoto Ito: Ceramidase Enhances Phospholipase C-induced Hemolysis by Pseudomonas aeruginosa
J. Biol. Chem. 2007 282: 6021-6030. First Published on January 3, 2007; doi:10.1074/jbc.M603088200 [Abstract] [Full Text] [PDF]

Hideo Shindou, Daisuke Hishikawa, Hiroki Nakanishi, Takeshi Harayama, Satoshi Ishii, Ryo Taguchi, and Takao Shimizu: A Single Enzyme Catalyzes Both Platelet-activating Factor Production and Membrane Biogenesis of Inflammatory Cells: CLONING AND CHARACTERIZATION OF ACETYL-CoA:LYSO-PAF ACETYLTRANSFERASE
J. Biol. Chem. 2007 282: 6532-6539. First Published on December 20, 2006; doi:10.1074/jbc.M609641200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Shafik M. Sidani, Philipp Kirchhoff, Thenral Socrates, Lars Stelter, Elisa Ferreira, Christina Caputo, Kurt E. Roberts, Robert L. Bell, Marie E. Egan, and John P. Geibel: ${Delta}$ F508 Mutation Results in Impaired Gastric Acid Secretion
J. Biol. Chem. 2007 282: 6068-6074. First Published on December 18, 2006; doi:10.1074/jbc.M608427200 [Abstract] [Full Text] [PDF]

James B. Bruns, Marcelo D. Carattino, Shaohu Sheng, Ahmad B. Maarouf, Ora A. Weisz, Joseph M. Pilewski, Rebecca P. Hughey, and Thomas R. Kleyman: Epithelial Na⁺ Channels Are Fully Activated by Furin- and Prostasin-dependent Release of an Inhibitory Peptide from the ${gamma}$ -Subunit
J. Biol. Chem. 2007 282: 6153-6160. First Published on January 1, 2007; doi:10.1074/jbc.M610636200 [Abstract] [Full Text] [PDF]

Ignacio Giménez and Biff Forbush: The Residues Determining Differences in Ion Affinities among the Alternative Splice Variants F, A, and B of the Mammalian Renal Na-K-Cl Cotransporter (NKCC2)
J. Biol. Chem. 2007 282: 6540-6547. First Published on December 23, 2006; doi:10.1074/jbc.M610780200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Javed N. Agrewala, Deborah M. Brown, Nancy M. Lepak, Debra Duso, Gail Huston, and Susan L. Swain: Unique Ability of Activated CD4⁺ T Cells but Not Rested Effectors to Migrate to Non-lymphoid Sites in the Absence of Inflammation
J. Biol. Chem. 2007 282: 6106-6115. First Published on December 29, 2006; doi:10.1074/jbc.M608266200 [Abstract] [Full Text] [PDF]

Shekar Menon, Jaemin Lee, William A. Abplanalp, Sung-Eun Yoo, Takashi Agui, Sen-ichi Furudate, Paul S. Kim, and Peter Arvan: Oxidoreductase Interactions Include a Role for ERp72 Engagement with Mutant Thyroglobulin from the rdw/rdw Rat Dwarf
J. Biol. Chem. 2007 282: 6183-6191. First Published on January 2, 2007; doi:10.1074/jbc.M608863200 [Abstract] [Full Text] [PDF]

Kenneth W. Adams and Geoffrey M. Cooper: Rapid Turnover of Mcl-1 Couples Translation to Cell Survival and Apoptosis
J. Biol. Chem. 2007 282: 6192-6200. First Published on January 2, 2007; doi:10.1074/jbc.M610643200 [Abstract] [Full Text] [PDF]

Juxing Chen and Caroline A. Enns: The Cytoplasmic Domain of Transferrin Receptor 2 Dictates Its Stability and Response to Holo-transferrin in Hep3B Cells
J. Biol. Chem. 2007 282: 6201-6209. First Published on January 2, 2007; doi:10.1074/jbc.M610127200 [Abstract] [Full Text] [PDF]

Ping Li, Ning Jiang, Shanmugam Nagarajan, Robert Wohlhueter, Periasamy Selvaraj, and Cheng Zhu: Affinity and Kinetic Analysis of Fc ${gamma}$ Receptor IIIa (CD16a) Binding to IgG Ligands
J. Biol. Chem. 2007 282: 6210-6221. First Published on January 3, 2007; doi:10.1074/jbc.M609064200 [Abstract] [Full Text] [PDF]

Mike P. Storm, Heather K. Bone, Craig G. Beck, Pierre-Yves Bourillot, Valerie Schreiber, Teresa Damiano, Adam Nelson, Pierre Savatier, and Melanie J. Welham: Regulation of Nanog Expression by Phosphoinositide 3-Kinase-dependent Signaling in Murine Embryonic Stem Cells
J. Biol. Chem. 2007 282: 6265-6273. First Published on January 4, 2007; doi:10.1074/jbc.M610906200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Katharine H. Wrighton, Min Liang, Brad Bryan, Kunxin Luo, Mingyao Liu, Xin-Hua Feng, and Xia Lin: Transforming Growth Factor- $beta$ -independent Regulation of Myogenesis by SnoN Sumoylation
J. Biol. Chem. 2007 282: 6517-6524. First Published on January 3, 2007; doi:10.1074/jbc.M610206200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yoko Uemoto, So-ichiro Suzuki, Nobuo Terada, Nobuhiko Ohno, Shinichi Ohno, Shinya Yamanaka, and Masayuki Komada: Specific Role of the Truncated $beta$ IV-Spectrin ${Sigma}$ 6 in Sodium Channel Clustering at Axon Initial Segments and Nodes of Ranvier
J. Biol. Chem. 2007 282: 6548-6555. First Published on December 29, 2006; doi:10.1074/jbc.M609223200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yasuyuki Ohkawa, Saori Yoshimura, Chiduru Higashi, Concetta G. A. Marfella, Caroline S. Dacwag, Taro Tachibana, and Anthony N. Imbalzano: Myogenin and the SWI/SNF ATPase Brg1 Maintain Myogenic Gene Expression at Different Stages of Skeletal Myogenesis
J. Biol. Chem. 2007 282: 6564-6570. First Published on December 27, 2006; doi:10.1074/jbc.M608898200 [Abstract] [Full Text] [PDF]

Kevin W. McCool, Xiaojie Xu, Don B. Singer, Fern E. Murdoch, and Michael K. Fritsch: The Role of Histone Acetylation in Regulating Early Gene Expression Patterns during Early Embryonic Stem Cell Differentiation
J. Biol. Chem. 2007 282: 6696-6706. First Published on January 4, 2007; doi:10.1074/jbc.M609519200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jelena Jovanovic, Junichi Takagi, Laurence Choulier, Nicola G. A. Abrescia, David I. Stuart, P. Anton van der Merwe, Helen J. Mardon, and Penny A. Handford: ${alpha}$ V $beta$ 6 Is a Novel Receptor for Human Fibrillin-1: COMPARATIVE STUDIES OF MOLECULAR DETERMINANTS UNDERLYING INTEGRIN-RGD AFFINITY AND SPECIFICITY
J. Biol. Chem. 2007 282: 6743-6751. First Published on December 11, 2006; doi:10.1074/jbc.M607008200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tiziana Crepaldi, Francesca Bersani, Claudio Scuoppo, Paolo Accornero, Chiara Prunotto, Riccardo Taulli, Paolo E. Forni, Christian Leo, Roberto Chiarle, Jennifer Griffiths, David J. Glass, and Carola Ponzetto: Conditional Activation of MET in Differentiated Skeletal Muscle Induces Atrophy
J. Biol. Chem. 2007 282: 6812-6822. First Published on December 27, 2006; doi:10.1074/jbc.M610916200 [Abstract] [Full Text] [PDF]

Masaya Tanno, Jun Sakamoto, Tetsuji Miura, Kazuaki Shimamoto, and Yoshiyuki Horio: Nucleocytoplasmic Shuttling of the NAD⁺-dependent Histone Deacetylase SIRT1
J. Biol. Chem. 2007 282: 6823-6832. First Published on December 30, 2006; doi:10.1074/jbc.M609554200 [Abstract] [Full Text] [PDF]

Wendy M. Knosp, Chie Saneyoshi, Siming Shou, Hans Peter Bächinger, and H. Scott Stadler: Elucidation, Quantitative Refinement, and in Vivo Utilization of the HOXA13 DNA Binding Site
J. Biol. Chem. 2007 282: 6843-6853. First Published on January 1, 2007; doi:10.1074/jbc.M610775200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tania Aguado, Arkaitz Carracedo, Boris Julien, Guillermo Velasco, Garry Milman, Raphael Mechoulam, Luis Alvarez, Manuel Guzmán, and Ismael Galve-Roperh: Cannabinoids Induce Glioma Stem-like Cell Differentiation and Inhibit Gliomagenesis
J. Biol. Chem. 2007 282: 6854-6862. First Published on January 2, 2007; doi:10.1074/jbc.M608900200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Jiangong Niu, Zhe Chang, Bailu Peng, Qianghua Xia, Weiqin Lu, Peng Huang, Ming-Sound Tsao, and Paul J. Chiao: Keratinocyte Growth Factor/Fibroblast Growth Factor-7-regulated Cell Migration and Invasion through Activation of NF- ${kappa}$ B Transcription Factors
J. Biol. Chem. 2007 282: 6001-6011. First Published on January 2, 2007; doi:10.1074/jbc.M606878200 [Abstract] [Full Text] [PDF]

Jianhong Yao, Tae Whan Kim, Jinzhong Qin, Zhengfan Jiang, Youcun Qian, Hui Xiao, Yi Lu, Wen Qian, Muhammet Fatih Gulen, Nywana Sizemore, Joseph DiDonato, Shintaro Sato, Shizuo Akira, Bing Su, and Xiaoxia Li: Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NF ${kappa}$ B Activation Pathways Bifurcate at IL-1 Receptor-associated Kinase Modification
J. Biol. Chem. 2007 282: 6075-6089. First Published on December 29, 2006; doi:10.1074/jbc.M609039200 [Abstract] [Full Text] [PDF]

Xiao-Pei Gao, Xiangdong Zhu, Jian Fu, Qinghui Liu, Randall S. Frey, and Asrar B. Malik: Blockade of Class IA Phosphoinositide 3-Kinase in Neutrophils Prevents NADPH Oxidase Activation- and Adhesion-dependent Inflammation
J. Biol. Chem. 2007 282: 6116-6125. First Published on December 29, 2006; doi:10.1074/jbc.M610248200 [Abstract] [Full Text] [PDF]

Sabine Rosenberger, Irmgard S. Thorey, Sabine Werner, and Petra Boukamp: A Novel Regulator of Telomerase: S100A8 MEDIATES DIFFERENTIATION-DEPENDENT AND CALCIUM-INDUCED INHIBITION OF TELOMERASE ACTIVITY IN THE HUMAN EPIDERMAL KERATINOCYTE LINE HaCaT
J. Biol. Chem. 2007 282: 6126-6135. First Published on December 29, 2006; doi:10.1074/jbc.M610529200 [Abstract] [Full Text] [PDF]

Zhida Zheng, Guozhou Chen, Shreyas Joshi, Evan D. Brutinel, Timothy L. Yahr, and Lingling Chen: Biochemical Characterization of a Regulatory Cascade Controlling Transcription of the Pseudomonas aeruginosa Type III Secretion System
J. Biol. Chem. 2007 282: 6136-6142. First Published on December 29, 2006; doi:10.1074/jbc.M611664200 [Abstract] [Full Text] [PDF]

Tarek Z. Deeb, Jane E. Carland, Michelle A. Cooper, Matthew R. Livesey, Jeremy J. Lambert, John A. Peters, and Tim G. Hales: Dynamic Modification of a Mutant Cytoplasmic Cysteine Residue Modulates the Conductance of the Human 5-HT_3A Receptor
J. Biol. Chem. 2007 282: 6172-6182. First Published on January 2, 2007; doi:10.1074/jbc.M607698200 [Abstract] [Full Text] [PDF]

Kate A. Alford, Sarah Glennie, Bryony R. Turrell, Lesley Rawlinson, Jeremy Saklatvala, and Jonathan L. E. Dean: Heat Shock Protein 27 Functions in Inflammatory Gene Expression and Transforming Growth Factor- $beta$ -activated Kinase-1 (TAK1)-mediated Signaling
J. Biol. Chem. 2007 282: 6232-6241. First Published on January 3, 2007; doi:10.1074/jbc.M610987200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hong Lu, Jeng Yih Wu, Ellen J. Beswick, Tomoyuki Ohno, Stefan Odenbreit, Rainer Haas, Victor E. Reyes, Masakazu Kita, David Y. Graham, and Yoshio Yamaoka: Functional and Intracellular Signaling Differences Associated with the Helicobacter pylori AlpAB Adhesin from Western and East Asian Strains
J. Biol. Chem. 2007 282: 6242-6254. First Published on January 3, 2007; doi:10.1074/jbc.M611178200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Naval P. Shanware, Anthony T. Trinh, Leah M. Williams, and Randal S. Tibbetts: Coregulated Ataxia Telangiectasia-mutated and Casein Kinase Sites Modulate cAMP-response Element-binding Protein-Coactivator Interactions in Response to DNA Damage
J. Biol. Chem. 2007 282: 6283-6291. First Published on January 5, 2007; doi:10.1074/jbc.M610674200 [Abstract] [Full Text] [PDF]

Mackenzie E. Malo, Liang Li, and Larry Fliegel: Mitogen-activated Protein Kinase-dependent Activation of the Na⁺/H⁺ Exchanger Is Mediated through Phosphorylation of Amino Acids Ser⁷⁷⁰ and Ser⁷⁷¹
J. Biol. Chem. 2007 282: 6292-6299. First Published on January 5, 2007; doi:10.1074/jbc.M611073200 [Abstract] [Full Text] [PDF]

Yaozu Ye, Celia Quijano, Kristine M. Robinson, Karina C. Ricart, Amy L. Strayer, Mary Anne Sahawneh, John J. Shacka, Marion Kirk, Stephen Barnes, Mary Ann Accavitti-Loper, Rafael Radi, Joseph S. Beckman, and Alvaro G. Estévez: Prevention of Peroxynitrite-induced Apoptosis of Motor Neurons and PC12 Cells by Tyrosine-containing Peptides
J. Biol. Chem. 2007 282: 6324-6337. First Published on January 2, 2007; doi:10.1074/jbc.M610800200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Michael F. Mesleh, William A. Shirley, Christopher E. Heise, Nicholas Ling, Richard A. Maki, and Richard P. Laura: NMR Structural Characterization of a Minimal Peptide Antagonist Bound to the Extracellular Domain of the Corticotropin-releasing Factor₁ Receptor
J. Biol. Chem. 2007 282: 6338-6346. First Published on December 27, 2006; doi:10.1074/jbc.M609816200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Matthew A. Jones, Kevin A. Feeney, Sharon M. Kelly, and John M. Christie: Mutational Analysis of Phototropin 1 Provides Insights into the Mechanism Underlying LOV2 Signal Transmission
J. Biol. Chem. 2007 282: 6405-6414. First Published on December 12, 2006; doi:10.1074/jbc.M605969200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data]

Iván Plaza-Menacho, Tineke van der Sluis, Harry Hollema, Oliver Gimm, Charles H. C. M. Buys, Anthony I. Magee, Clare M. Isacke, Robert M. W. Hofstra, and Bart J. L. Eggen: Ras/ERK1/2-mediated STAT3 Ser⁷²⁷ Phosphorylation by Familial Medullary Thyroid Carcinoma-associated RET Mutants Induces Full Activation of STAT3 and Is Required for c-fos Promoter Activation, Cell Mitogenicity, and Transformation
J. Biol. Chem. 2007 282: 6415-6424. First Published on January 5, 2007; doi:10.1074/jbc.M608952200 [Abstract] [Full Text] [PDF]

Yuan Wei, Beth Zavilowitz, Lisa M. Satlin, and Wen-Hui Wang: Angiotensin II Inhibits the ROMK-like Small Conductance K Channel in Renal Cortical Collecting Duct during Dietary Potassium Restriction
J. Biol. Chem. 2007 282: 6455-6462. First Published on December 28, 2006; doi:10.1074/jbc.M607477200 [Abstract] [Full Text] [PDF]

Ceniz Zihni, Costas Mitsopoulos, Ignatius A. Tavares, Buzz Baum, Anne J. Ridley, and Jonathan D. H. Morris: Prostate-derived Sterile 20-like Kinase 1- ${alpha}$ Induces Apoptosis: JNK- AND CASPASE-DEPENDENT NUCLEAR LOCALIZATION IS A REQUIREMENT FOR MEMBRANE BLEBBING
J. Biol. Chem. 2007 282: 6484-6493. First Published on December 11, 2006; doi:10.1074/jbc.M608336200 [Abstract] [Full Text] [PDF]

Davin Jagnandan, Jarrod E. Church, Botond Banfi, Dennis J. Stuehr, Mario B. Marrero, and David J. R. Fulton: Novel Mechanism of Activation of NADPH Oxidase 5: CALCIUM SENSITIZATION VIA PHOSPHORYLATION
J. Biol. Chem. 2007 282: 6494-6507. First Published on December 12, 2006; doi:10.1074/jbc.M608966200 [Abstract] [Full Text] [PDF]

Jiangchuan Tao, Hsien-yu Wang, and Craig C. Malbon: Src Docks to A-kinase Anchoring Protein Gravin, Regulating $beta$ ₂-Adrenergic Receptor Resensitization and Recycling
J. Biol. Chem. 2007 282: 6597-6608. First Published on January 2, 2007; doi:10.1074/jbc.M608927200 [Abstract] [Full Text] [PDF]

Tong Li, Lorraine E. Chalifour, and Hemant K. Paudel: Phosphorylation of Protein Phosphatase 1 by Cyclin-dependent Protein Kinase 5 during Nerve Growth Factor-induced PC12 Cell Differentiation
J. Biol. Chem. 2007 282: 6619-6628. First Published on January 3, 2007; doi:10.1074/jbc.M606347200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hiroo Imai, Vladimir Kefalov, Keisuke Sakurai, Osamu Chisaka, Yoshiki Ueda, Akishi Onishi, Takefumi Morizumi, Yingbin Fu, Kazuhisa Ichikawa, Kei Nakatani, Yoshihito Honda, Jeannie Chen, King-Wai Yau, and Yoshinori Shichida: Molecular Properties of Rhodopsin and Rod Function
J. Biol. Chem. 2007 282: 6677-6684. First Published on December 28, 2006; doi:10.1074/jbc.M610086200 [Abstract] [Full Text] [PDF]

Sivaprakasam Balasubramanian and Richard L. Eckert: Curcumin Suppresses AP1 Transcription Factor-dependent Differentiation and Activates Apoptosis in Human Epidermal Keratinocytes
J. Biol. Chem. 2007 282: 6707-6715. First Published on December 5, 2006; doi:10.1074/jbc.M606003200 [Abstract] [Full Text] [PDF]

Maya T. Kunkel, Alex Toker, Roger Y. Tsien, and Alexandra C. Newton: Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter
J. Biol. Chem. 2007 282: 6733-6742. First Published on December 21, 2006; doi:10.1074/jbc.M608086200 [Abstract] [Full Text] [PDF]

Mario Serrano, Silke Robatzek, Martha Torres, Erich Kombrink, Imre E. Somssich, Mike Robinson, and Paul Schulze-Lefert: Chemical Interference of Pathogen-associated Molecular Pattern-triggered Immune Responses in Arabidopsis Reveals a Potential Role for Fatty-acid Synthase Type II Complex-derived Lipid Signals
J. Biol. Chem. 2007 282: 6803-6811. First Published on December 13, 2006; doi:10.1074/jbc.M608792200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Peter Rellos, Frank J. Ivins, Joanne E. Baxter, Ashley Pike, Timothy J. Nott, Donna-Marie Parkinson, Sanjan Das, Steven Howell, Oleg Fedorov, Qi Yu Shen, Andrew M. Fry, Stefan Knapp, and Stephen J. Smerdon: Structure and Regulation of the Human Nek2 Centrosomal Kinase
J. Biol. Chem. 2007 282: 6833-6842. First Published on December 31, 2006; doi:10.1074/jbc.M609721200 [Abstract] [Full Text] [PDF] [Supplemental Data]

John R. Basile, Kenn Holmbeck, Thomas H. Bugge, and J. Silvio Gutkind: MT1-MMP Controls Tumor-induced Angiogenesis through the Release of Semaphorin 4D
J. Biol. Chem. 2007 282: 6899-6905. First Published on January 4, 2007; doi:10.1074/jbc.M609570200 [Abstract] [Full Text] [PDF]

Mohd W. Nasser, Sandeep K. Raghuwanshi, Kimberly M. Malloy, Pavani Gangavarapu, Joong-Youn Shim, Krishna Rajarathnam, and Ricardo M. Richardson: CXCR1 and CXCR2 Activation and Regulation: ROLE OF ASPARTATE 199 OF THE SECOND EXTRACELLULAR LOOP OF CXCR2 IN CXCL8-MEDIATED RAPID RECEPTOR INTERNALIZATION
J. Biol. Chem. 2007 282: 6906-6915. First Published on January 4, 2007; doi:10.1074/jbc.M610289200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

York Tomita, Natasha Marchenko, Susan Erster, Alice Nemajerova, Alexander Dehner, Christian Klein, Hongguang Pan, Horst Kessler, Petr Pancoska, and Ute M. Moll: WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization. VOLUME 281 (2006) PAGES 8600-8606
J. Biol. Chem. 2007 282: 6916. [Full Text] [PDF]