JBC -- Table of Contents (Apr 4 2008, 283, (14))

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Serge N. Vinogradov and Luc Moens: Diversity of Globin Function: Enzymatic, Transport, Storage, and Sensing
J. Biol. Chem. 2008 283: 8773-8777. First Published on January 22, 2008; doi:10.1074/jbc.R700029200 [Full Text] [PDF] [Supplemental Data]

Accelerated Publications:

Andrey P. Babenko: A Novel ABCC8 (SUR1)-dependent Mechanism of Metabolism-Excitation Uncoupling
J. Biol. Chem. 2008 283: 8778-8782. First Published on February 15, 2008; doi:10.1074/jbc.C700243200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Oxana A. Malakhova and Dong-Er Zhang: ISG15 Inhibits Nedd4 Ubiquitin E3 Activity and Enhances the Innate Antiviral Response
J. Biol. Chem. 2008 283: 8783-8787. First Published on February 20, 2008; doi:10.1074/jbc.C800030200 [Abstract] [Full Text] [PDF] [Summary]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Pingfang Liu, Jacob A. Theruvathu, Agus Darwanto, Victoria Valinluck Lao, Tod Pascal, William Goddard, III, and Lawrence C. Sowers: Mechanisms of Base Selection by the Escherichia coli Mispaired Uracil Glycosylase
J. Biol. Chem. 2008 283: 8829-8836. First Published on January 20, 2008; doi:10.1074/jbc.M707174200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Brian D. Beck, Su-Jung Park, Young-Ju Lee, Yaritzabel Roman, Robert A. Hromas, and Suk-Hee Lee: Human Pso4 Is a Metnase (SETMAR)-binding Partner That Regulates Metnase Function in DNA Repair
J. Biol. Chem. 2008 283: 9023-9030. First Published on February 8, 2008; doi:10.1074/jbc.M800150200 [Abstract] [Full Text] [PDF]

Junya Tomida, Yuji Masuda, Hidekazu Hiroaki, Tomoko Ishikawa, Ihnyoung Song, Toshiki Tsurimoto, Satoshi Tateishi, Tadahiro Shiomi, Yasuhiro Kamei, Jinhyeong Kim, Kenji Kamiya, Cyrus Vaziri, Haruo Ohmori, and Takeshi Todo: DNA Damage-induced Ubiquitylation of RFC2 Subunit of Replication Factor C Complex
J. Biol. Chem. 2008 283: 9071-9079. First Published on February 1, 2008; doi:10.1074/jbc.M709835200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L. Boyer, Bernard P. Roques, Stephen H. Hughes, Baek Kim, and Robert A. Bambara: Apparent Defects in Processive DNA Synthesis, Strand Transfer, and Primer Elongation of Met-184 Mutants of HIV-1 Reverse Transcriptase Derive Solely from a dNTP Utilization Defect
J. Biol. Chem. 2008 283: 9196-9205. First Published on January 24, 2008; doi:10.1074/jbc.M710148200 [Abstract] [Full Text] [PDF]

Varuni K Jamburuthugoda, Jose M. Santos-Velazquez, Mark Skasko, Darwin J. Operario, Vandana Purohit, Pauline Chugh, Erika A. Szymanski, Joseph E. Wedekind, Robert A. Bambara, and Baek Kim: Reduced dNTP Binding Affinity of 3TC-resistant M184I HIV-1 Reverse Transcriptase Variants Responsible for Viral Infection Failure in Macrophage
J. Biol. Chem. 2008 283: 9206-9216. First Published on January 24, 2008; doi:10.1074/jbc.M710149200 [Abstract] [Full Text] [PDF]

Transcription, Chromatin, and Epigenetics:

William Brandt, Melin Khandekar, Norio Suzuki, Masayuki Yamamoto, Kim-Chew Lim, and James Douglas Engel: Defining the Functional Boundaries of the Gata2 Locus by Rescue with a Linked Bacterial Artificial Chromosome Transgene
J. Biol. Chem. 2008 283: 8976-8983. First Published on January 21, 2008; doi:10.1074/jbc.M709364200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Per Antonson, Tomas Jakobsson, Tova Almlöf, Karolin Guldevall, Knut R. Steffensen, and Jan-Åke Gustafsson: RAP250 Is a Coactivator in the Transforming Growth Factor β Signaling Pathway That Interacts with Smad2 and Smad3
J. Biol. Chem. 2008 283: 8995-9001. First Published on February 7, 2008; doi:10.1074/jbc.M707203200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kazuki Mochizuki, Akira Nishiyama, Moon Kyoo Jang, Anup Dey, Anu Ghosh, Tomohiko Tamura, Hiroko Natsume, Hongjie Yao, and Keiko Ozato: The Bromodomain Protein Brd4 Stimulates G₁ Gene Transcription and Promotes Progression to S Phase
J. Biol. Chem. 2008 283: 9040-9048. First Published on January 27, 2008; doi:10.1074/jbc.M707603200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kyunghwan Kim, Jongkyu Choi, Kyu Heo, Hyunjung Kim, David Levens, Kimitoshi Kohno, Edward M. Johnson, Hugh W. Brock, and Woojin An: Isolation and Characterization of a Novel H1.2 Complex That Acts as a Repressor of p53-mediated Transcription
J. Biol. Chem. 2008 283: 9113-9126. First Published on February 7, 2008; doi:10.1074/jbc.M708205200 [Abstract] [Full Text] [PDF]

Shinichi Itoh, Ha Won Kim, Osamu Nakagawa, Kiyoshi Ozumi, Susan M. Lessner, Hiroki Aoki, Kamran Akram, Ronald D. McKinney, Masuko Ushio-Fukai, and Tohru Fukai: Novel Role of Antioxidant-1 (Atox1) as a Copper-dependent Transcription Factor Involved in Cell Proliferation
J. Biol. Chem. 2008 283: 9157-9167. First Published on February 2, 2008; doi:10.1074/jbc.M709463200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Myriam Ekici, Mathias Hohl, Frans Schuit, Alberto Martínez-Serrano, and Gerald Thiel: Transcription of Genes Encoding Synaptic Vesicle Proteins in Human Neural Stem Cells: CHROMATIN ACCESSIBILITY, HISTONE METHYLATION PATTERN, AND THE ESSENTIAL ROLE OF REST
J. Biol. Chem. 2008 283: 9257-9268. First Published on January 30, 2008; doi:10.1074/jbc.M709388200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translational Modification, and Degradation:

Sarit-Sara Sivan, Ellen Wachtel, Eve Tsitron, Nico Sakkee, Frits van der Ham, Jeroen DeGroot, Sally Roberts, and Alice Maroudas: Collagen Turnover in Normal and Degenerate Human Intervertebral Discs as Determined by the Racemization of Aspartic Acid
J. Biol. Chem. 2008 283: 8796-8801. First Published on February 4, 2008; doi:10.1074/jbc.M709885200 [Abstract] [Full Text] [PDF]

Keiko Sekine, Kohei Takubo, Ryo Kikuchi, Michie Nishimoto, Masayuki Kitagawa, Fuminori Abe, Kiyohiro Nishikawa, Takashi Tsuruo, and Mikihiko Naito: Small Molecules Destabilize cIAP1 by Activating Auto-ubiquitylation
J. Biol. Chem. 2008 283: 8961-8968. First Published on January 29, 2008; doi:10.1074/jbc.M709525200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lilien N. Voong, Allison R. Slater, Sebila Kratovac, and Drew E. Cressman: Mitogen-activated Protein Kinase ERK1/2 Regulates the Class II Transactivator
J. Biol. Chem. 2008 283: 9031-9039. First Published on February 1, 2008; doi:10.1074/jbc.M706487200 [Abstract] [Full Text] [PDF]

Kimberly R. Marshall-Batty and Hiroshi Nakai: Activation of a Dormant ClpX Recognition Motif of Bacteriophage Mu Repressor by Inducing High Local Flexibility
J. Biol. Chem. 2008 283: 9060-9070. First Published on January 28, 2008; doi:10.1074/jbc.M705508200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chelsea R. Sprague, Tamara S. Fraley, Hyo Sang Jang, Sangeet Lal, and Jeffrey A. Greenwood: Phosphoinositide Binding to the Substrate Regulates Susceptibility to Proteolysis by Calpain
J. Biol. Chem. 2008 283: 9217-9223. First Published on February 6, 2008; doi:10.1074/jbc.M707436200 [Abstract] [Full Text] [PDF]

Daisheng Song and Frank S. Lee: A Role for IOP1 in Mammalian Cytosolic Iron-Sulfur Protein Biogenesis
J. Biol. Chem. 2008 283: 9231-9238. First Published on February 12, 2008; doi:10.1074/jbc.M708077200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Claes Andréasson, Jocelyne Fiaux, Heike Rampelt, Matthias P. Mayer, and Bernd Bukau: Hsp110 Is a Nucleotide-activated Exchange Factor for Hsp70
J. Biol. Chem. 2008 283: 8877-8884. First Published on January 24, 2008; doi:10.1074/jbc.M710063200 [Abstract] [Full Text] [PDF]

Mark O. Huising, Joan M. Vaughan, Shaili H. Shah, Katherine L. Grillot, Cynthia J. Donaldson, Jean Rivier, Gert Flik, and Wylie W. Vale: Residues of Corticotropin Releasing Factor-binding Protein (CRF-BP) That Selectively Abrogate Binding to CRF but Not to Urocortin 1
J. Biol. Chem. 2008 283: 8902-8912. First Published on January 29, 2008; doi:10.1074/jbc.M709904200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Alexander Pautsch, Nadja Stadler, Oliver Wissdorf, Elke Langkopf, Werner Moreth, and Rüdiger Streicher: Molecular Recognition of the Protein Phosphatase 1 Glycogen Targeting Subunit by Glycogen Phosphorylase
J. Biol. Chem. 2008 283: 8913-8918. First Published on January 15, 2008; doi:10.1074/jbc.M706612200 [Abstract] [Full Text] [PDF]

Ylva Ivarsson, Carlo Travaglini-Allocatelli, Maurizio Brunori, and Stefano Gianni: Folding and Misfolding in a Naturally Occurring Circularly Permuted PDZ Domain
J. Biol. Chem. 2008 283: 8954-8960. First Published on February 7, 2008; doi:10.1074/jbc.M707424200 [Abstract] [Full Text] [PDF]

Heath Ecroyd, Tomas Koudelka, David C. Thorn, Danielle M. Williams, Glyn Devlin, Peter Hoffmann, and John A. Carver: Dissociation from the Oligomeric State Is the Rate-limiting Step in Fibril Formation by ${kappa}$ -Casein
J. Biol. Chem. 2008 283: 9012-9022. First Published on February 1, 2008; doi:10.1074/jbc.M709928200 [Abstract] [Full Text] [PDF]

Hiroshi Okuda, Chihaya Sakuhana, Risa Yamamoto, Yuko Mizukami, Rika Kawai, Yusuke Sumita, Motoki Koga, Mutsunori Shirai, and Kazuhiko Matsuda: The Intermediate Domain Defines Broad Nucleotide Selectivity for Protein Folding in Chlamydophila GroEL1
J. Biol. Chem. 2008 283: 9300-9307. First Published on January 29, 2008; doi:10.1074/jbc.M710057200 [Abstract] [Full Text] [PDF] [Supplemental Data]

José A. Gavira, Ana Camara-Artigas, Walleska De Jesús-Bonilla, Juan López-Garriga, Ariel Lewis, Ruth Pietri, Syun-Ru Yeh, Carmen L. Cadilla, and Juan Manuel García-Ruiz: Structure and Ligand Selection of Hemoglobin II from Lucina pectinata
J. Biol. Chem. 2008 283: 9414-9423. First Published on January 18, 2008; doi:10.1074/jbc.M705026200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ryan P. McAndrew, Yudong Wang, Al-Walid Mohsen, Miao He, Jerry Vockley, and Jung-Ja P. Kim: Structural Basis for Substrate Fatty Acyl Chain Specificity: CRYSTAL STRUCTURE OF HUMAN VERY-LONG-CHAIN ACYL-CoA DEHYDROGENASE
J. Biol. Chem. 2008 283: 9435-9443. First Published on January 28, 2008; doi:10.1074/jbc.M709135200 [Abstract] [Full Text] [PDF]

Henry G. Hocking, Andrew P. Herbert, David Kavanagh, Dinesh C. Soares, Viviana P. Ferreira, Michael K. Pangburn, Dusan Uhrín, and Paul N. Barlow: Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations
J. Biol. Chem. 2008 283: 9475-9487. First Published on February 5, 2008; doi:10.1074/jbc.M709587200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Enzyme Catalysis and Regulation:

Nobuhiro Ikezawa, Kinuko Iwasa, and Fumihiko Sato: Molecular Cloning and Characterization of CYP80G2, a Cytochrome P450 That Catalyzes an Intramolecular C–C Phenol Coupling of (S)-Reticuline in Magnoflorine Biosynthesis, from Cultured Coptis japonica Cells
J. Biol. Chem. 2008 283: 8810-8821. First Published on January 29, 2008; doi:10.1074/jbc.M705082200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jonathan H. Foley, Paula Kim, and Michael E. Nesheim: Thrombin-activable Fibrinolysis Inhibitor Zymogen Does Not Play a Significant Role in the Attenuation of Fibrinolysis
J. Biol. Chem. 2008 283: 8863-8867. First Published on February 5, 2008; doi:10.1074/jbc.M800127200 [Abstract] [Full Text] [PDF]

Mirko Zaffagnini, Laure Michelet, Vincent Massot, Paolo Trost, and Stéphane D. Lemaire: Biochemical Characterization of Glutaredoxins from Chlamydomonas reinhardtii Reveals the Unique Properties of a Chloroplastic CGFS-type Glutaredoxin
J. Biol. Chem. 2008 283: 8868-8876. First Published on January 23, 2008; doi:10.1074/jbc.M709567200 [Abstract] [Full Text] [PDF]

Yoko Ogasawara, Hidetaka Kaya, Goro Hiraoka, Fumiaki Yumoto, Sachie Kimura, Yasuhiro Kadota, Haruka Hishinuma, Eriko Senzaki, Satoshi Yamagoe, Koji Nagata, Masayuki Nara, Kazuo Suzuki, Masaru Tanokura, and Kazuyuki Kuchitsu: Synergistic Activation of the Arabidopsis NADPH Oxidase AtrbohD by Ca²⁺ and Phosphorylation
J. Biol. Chem. 2008 283: 8885-8892. First Published on January 23, 2008; doi:10.1074/jbc.M708106200 [Abstract] [Full Text] [PDF]

Sandra S. Szegedi, Carmen C. Castro, Markos Koutmos, and Timothy A. Garrow: Betaine-Homocysteine S-Methyltransferase-2 Is an S-Methylmethionine-Homocysteine Methyltransferase
J. Biol. Chem. 2008 283: 8939-8945. First Published on January 29, 2008; doi:10.1074/jbc.M710449200 [Abstract] [Full Text] [PDF]

Rakhi Agarwal, Stephen K. Burley, and Subramanyam Swaminathan: Structure of Human Dual Specificity Protein Phosphatase 23, VHZ, Enzyme-Substrate/Product Complex
J. Biol. Chem. 2008 283: 8946-8953. First Published on February 1, 2008; doi:10.1074/jbc.M708945200 [Abstract] [Full Text] [PDF]

Paramjit S. Bansal, Allan M. Torres, Ben Crossett, Karen K. Y. Wong, Jennifer M. S. Koh, Dominic P. Geraghty, Jamie I. Vandenberg, and Philip W. Kuchel: Substrate Specificity of Platypus Venom L-to-D-Peptide Isomerase
J. Biol. Chem. 2008 283: 8969-8975. First Published on December 24, 2007; doi:10.1074/jbc.M709762200 [Abstract] [Full Text] [PDF]

Simon L. Newstead, Jane A. Potter, Jennifer C. Wilson, Guogang Xu, Chin-Hsiang Chien, Andrew G. Watts, Stephen G. Withers, and Garry L. Taylor: The Structure of Clostridium perfringens NanI Sialidase and Its Catalytic Intermediates
J. Biol. Chem. 2008 283: 9080-9088. First Published on January 24, 2008; doi:10.1074/jbc.M710247200 [Abstract] [Full Text] [PDF]

Karin Kaiserova, Xian-Liang Tang, Sanjay Srivastava, and Aruni Bhatnagar: Role of Nitric Oxide in Regulating Aldose Reductase Activation in the Ischemic Heart
J. Biol. Chem. 2008 283: 9101-9112. First Published on January 27, 2008; doi:10.1074/jbc.M709671200 [Abstract] [Full Text] [PDF]

Longsheng Lai, Zhaohui Xu, Jiahai Zhou, Kyung-Dall Lee, and Gordon L. Amidon: Molecular Basis of Prodrug Activation by Human Valacyclovirase, an ${alpha}$ -Amino Acid Ester Hydrolase
J. Biol. Chem. 2008 283: 9318-9327. First Published on February 5, 2008; doi:10.1074/jbc.M709530200 [Abstract] [Full Text] [PDF] [Supplemental data]

Kuo-Kuang Wen, Melissa McKane, Jon C. D. Houtman, and Peter A. Rubenstein: Control of the Ability of Profilin to Bind and Facilitate Nucleotide Exchange from G-actin
J. Biol. Chem. 2008 283: 9444-9453. First Published on January 27, 2008; doi:10.1074/jbc.M709806200 [Abstract] [Full Text] [PDF]

Peter Gee, Pong Kian Chua, Jirair Gevorkyan, Klaus Klumpp, Isabel Najera, David C. Swinney, and Jerome Deval: Essential Role of the N-terminal Domain in the Regulation of RIG-I ATPase Activity
J. Biol. Chem. 2008 283: 9488-9496. First Published on February 11, 2008; doi:10.1074/jbc.M706777200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Liping Qiao, Chenhui Zou, Peng Shao, Jerome Schaack, Peter F. Johnson, and Jianhua Shao: Transcriptional Regulation of Fatty Acid Translocase/CD36 Expression by CCAAT/Enhancer-binding Protein ${alpha}$
J. Biol. Chem. 2008 283: 8788-8795. First Published on February 8, 2008; doi:10.1074/jbc.M800055200 [Abstract] [Full Text] [PDF]

Hisashi Ito, Makio Yokono, Ryouichi Tanaka, and Ayumi Tanaka: Identification of a Novel Vinyl Reductase Gene Essential for the Biosynthesis of Monovinyl Chlorophyll in Synechocystis sp. PCC6803
J. Biol. Chem. 2008 283: 9002-9011. First Published on January 29, 2008; doi:10.1074/jbc.M708369200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Alfred L. Fisher, Kathryn E. Page, Gordon J. Lithgow, and Lindsey Nash: The Caenorhabditis elegans K10C2.4 Gene Encodes a Member of the Fumarylacetoacetate Hydrolase Family: A CAENORHABDITIS ELEGANS MODEL OF TYPE I TYROSINEMIA
J. Biol. Chem. 2008 283: 9127-9135. First Published on January 28, 2008; doi:10.1074/jbc.M708341200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Daphne Pala, Mohit Kapoor, Anita Woods, Laura Kennedy, Shangxi Liu, Shioqiong Chen, Laura Bursell, Karen M. Lyons, David E. Carter, Frank Beier, and Andrew Leask: Focal Adhesion Kinase/Src Suppresses Early Chondrogenesis: CENTRAL ROLE OF CCN2
J. Biol. Chem. 2008 283: 9239-9247. First Published on February 13, 2008; doi:10.1074/jbc.M705175200 [Abstract] [Full Text] [PDF]

Vaishali N. Patel, Karen M. Likar, Simona Zisman-Rozen, Samuel N. Cowherd, Keyonica S. Lassiter, Ifat Sher, Edwin A. Yates, Jeremy E. Turnbull, Dina Ron, and Matthew P. Hoffman: Specific Heparan Sulfate Structures Modulate FGF10-mediated Submandibular Gland Epithelial Morphogenesis and Differentiation
J. Biol. Chem. 2008 283: 9308-9317. First Published on January 28, 2008; doi:10.1074/jbc.M709995200 [Abstract] [Full Text] [PDF]

Alicia R. Folgueras, Antonio Fueyo, Olivia García-Suárez, Jennifer Cox, Aurora Astudillo, Paolo Tortorella, Cristina Campestre, Ana Gutiérrez-Fernández, Miriam Fanjul-Fernández, Caroline J. Pennington, Dylan R. Edwards, Christopher M. Overall, and Carlos López-Otín: Collagenase-2 Deficiency or Inhibition Impairs Experimental Autoimmune Encephalomyelitis in Mice
J. Biol. Chem. 2008 283: 9465-9474. First Published on February 1, 2008; doi:10.1074/jbc.M709522200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling:

Venky Sreedhar Reddy, Arjun Kumar Singh, and Ram Rajasekharan: The Saccharomyces cerevisiae PHM8 Gene Encodes a Soluble Magnesium-dependent Lysophosphatidic Acid Phosphatase
J. Biol. Chem. 2008 283: 8846-8854. First Published on January 30, 2008; doi:10.1074/jbc.M706752200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gabriel M. Simon and Benjamin F. Cravatt: Anandamide Biosynthesis Catalyzed by the Phosphodiesterase GDE1 and Detection of Glycerophospho-N-acyl Ethanolamine Precursors in Mouse Brain
J. Biol. Chem. 2008 283: 9341-9349. First Published on January 27, 2008; doi:10.1074/jbc.M707807200 [Abstract] [Full Text] [PDF]

Yoshichika Kawai, Tomomi Nishikawa, Yuko Shiba, Satomi Saito, Kaeko Murota, Noriyuki Shibata, Makio Kobayashi, Masaya Kanayama, Koji Uchida, and Junji Terao: Macrophage as a Target of Quercetin Glucuronides in Human Atherosclerotic Arteries: IMPLICATION IN THE ANTI-ATHEROSCLEROTIC MECHANISM OF DIETARY FLAVONOIDS
J. Biol. Chem. 2008 283: 9424-9434. First Published on January 16, 2008; doi:10.1074/jbc.M706571200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Nikolai A. Braun and Steven M. Theg: The Chloroplast Tat Pathway Transports Substrates in the Dark
J. Biol. Chem. 2008 283: 8822-8828. First Published on January 9, 2008; doi:10.1074/jbc.M708948200 [Abstract] [Full Text] [PDF]

Mahuya Bose, Randy M. Whittal, Walter L. Miller, and Himangshu S. Bose: Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein
J. Biol. Chem. 2008 283: 8837-8845. First Published on February 4, 2008; doi:10.1074/jbc.M709221200 [Abstract] [Full Text] [PDF] AUTHOR'S CHOICE

Yajuan Gao, Cavita K. Chotoo, Corina M. Balut, Fei Sun, Mark A. Bailey, and Daniel C. Devor: Role of S3 and S4 Transmembrane Domain Charged Amino Acids in Channel Biogenesis and Gating of KCa2.3 and KCa3.1
J. Biol. Chem. 2008 283: 9049-9059. First Published on January 28, 2008; doi:10.1074/jbc.M708022200 [Abstract] [Full Text] [PDF]

Latha Devi, Vijayendran Raghavendran, Badanavalu M. Prabhu, Narayan G. Avadhani, and Hindupur K. Anandatheerthavarada: Mitochondrial Import and Accumulation of ${alpha}$ -Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain
J. Biol. Chem. 2008 283: 9089-9100. First Published on February 1, 2008; doi:10.1074/jbc.M710012200 [Abstract] [Full Text] [PDF]

Yu-Wen Lin, Jeremy D. Bushman, Fei-Fei Yan, Sara Haidar, Courtney MacMullen, Arupa Ganguly, Charles A. Stanley, and Show-Ling Shyng: Destabilization of ATP-sensitive Potassium Channel Activity by Novel KCNJ11 Mutations Identified in Congenital Hyperinsulinism
J. Biol. Chem. 2008 283: 9146-9156. First Published on February 4, 2008; doi:10.1074/jbc.M708798200 [Abstract] [Full Text] [PDF]

Stephanie Ravaud, Goran Stjepanovic, Klemens Wild, and Irmgard Sinning: The Crystal Structure of the Periplasmic Domain of the Escherichia coli Membrane Protein Insertase YidC Contains a Substrate Binding Cleft
J. Biol. Chem. 2008 283: 9350-9358. First Published on January 30, 2008; doi:10.1074/jbc.M710493200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pierre Hakizimana, Matthieu Masureel, Bénédicte Gbaguidi, Jean-Marie Ruysschaert, and Cédric Govaerts: Interactions between Phosphatidylethanolamine Headgroup and LmrP, a Multidrug Transporter: A CONSERVED MECHANISM FOR PROTON GRADIENT SENSING?
J. Biol. Chem. 2008 283: 9369-9376. First Published on January 30, 2008; doi:10.1074/jbc.M708427200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Billow A. Ahmed, Brandon C. Jeffus, Syed I. A. Bukhari, Justin T. Harney, Resat Unal, Vladimir V. Lupashin, Peter van der Sluijs, and Fusun Kilic: Serotonin Transamidates Rab4 and Facilitates Its Binding to the C Terminus of Serotonin Transporter
J. Biol. Chem. 2008 283: 9388-9398. First Published on January 28, 2008; doi:10.1074/jbc.M706367200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Jinmin Gao, Lihong Huo, Xiaoou Sun, Min Liu, Dengwen Li, Jin-Tang Dong, and Jun Zhou: The Tumor Suppressor CYLD Regulates Microtubule Dynamics and Plays a Role in Cell Migration
J. Biol. Chem. 2008 283: 8802-8809. First Published on January 24, 2008; doi:10.1074/jbc.M708470200 [Abstract] [Full Text] [PDF]

Branka Bogunovic, Milica Stojakovic, Leonard Chen, and Maja Maric: An Unexpected Functional Link between Lysosomal Thiol Reductase and Mitochondrial Manganese Superoxide Dismutase
J. Biol. Chem. 2008 283: 8855-8862. First Published on January 24, 2008; doi:10.1074/jbc.M708998200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shigekazu Tabata, Kimiko Kuroki, Jing Wang, Mizuho Kajikawa, Ikuo Shiratori, Daisuke Kohda, Hisashi Arase, and Katsumi Maenaka: Biophysical Characterization of O-Glycosylated CD99 Recognition by Paired Ig-like Type 2 Receptors
J. Biol. Chem. 2008 283: 8893-8901. First Published on January 30, 2008; doi:10.1074/jbc.M709793200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Melanie Theodore, Yumiko Kawai, Jianqi Yang, Yuliya Kleshchenko, Sekhar P. Reddy, Fernando Villalta, and Ifeanyi J. Arinze: Multiple Nuclear Localization Signals Function in the Nuclear Import of the Transcription Factor Nrf2
J. Biol. Chem. 2008 283: 8984-8994. First Published on January 31, 2008; doi:10.1074/jbc.M709040200 [Abstract] [Full Text] [PDF]

Margaret H. Magdesian, Milena M. V. F. Carvalho, Fabio A. Mendes, Leonardo M. Saraiva, Maria A. Juliano, Luiz Juliano, José Garcia-Abreu, and Sérgio T. Ferreira: Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling
J. Biol. Chem. 2008 283: 9359-9368. First Published on January 30, 2008; doi:10.1074/jbc.M707108200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Siriporn Patrakitkomjorn, Daiki Kobayashi, Takashi Morikawa, Masayo Morifuji Wilson, Nobuyuki Tsubota, Atsushi Irie, Tatsuya Ozawa, Masashi Aoki, Nariko Arimura, Kozo Kaibuchi, Hideyuki Saya, and Norie Araki: Neurofibromatosis Type 1 (NF1) Tumor Suppressor, Neurofibromin, Regulates the Neuronal Differentiation of PC12 Cells via Its Associating Protein, CRMP-2
J. Biol. Chem. 2008 283: 9399-9413. First Published on January 23, 2008; doi:10.1074/jbc.M708206200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yaohong Wang, Kamalakkannan Srinivasan, Mohammad Rizwan Siddiqui, Sudeep P. George, Alok Tomar, and Seema Khurana: A Novel Role for Villin in Intestinal Epithelial Cell Survival and Homeostasis
J. Biol. Chem. 2008 283: 9454-9464. First Published on January 15, 2008; doi:10.1074/jbc.M707962200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Isabelle Georis, Jennifer J. Tate, Terrance G. Cooper, and Evelyne Dubois: Tor Pathway Control of the Nitrogen-responsive DAL5 Gene Bifurcates at the Level of Gln3 and Gat1 Regulation in Saccharomyces cerevisiae
J. Biol. Chem. 2008 283: 8919-8929. First Published on February 1, 2008; doi:10.1074/jbc.M708811200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Edward Geisinger, Elizabeth A. George, Tom W. Muir, and Richard P. Novick: Identification of Ligand Specificity Determinants in AgrC, the Staphylococcus aureus Quorum-sensing Receptor
J. Biol. Chem. 2008 283: 8930-8938. First Published on January 25, 2008; doi:10.1074/jbc.M710227200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Wen Guo, John Flanagan, Ravi Jasuja, James Kirkland, Lan Jiang, and Shalender Bhasin: The Effects of Myostatin on Adipogenic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells Are Mediated through Cross-communication between Smad3 and Wnt/β-Catenin Signaling Pathways
J. Biol. Chem. 2008 283: 9136-9145. First Published on January 18, 2008; doi:10.1074/jbc.M708968200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yang Li, Zhulun Wang, Noboru Furukawa, Patrick Escaron, Jennifer Weiszmann, Gary Lee, Michelle Lindstrom, Jinsong Liu, Xiaohong Liu, Haoda Xu, Olga Plotnikova, Vidya Prasad, Nigel Walker, R. Marc Learned, and Jin-Long Chen: T2384, a Novel Antidiabetic Agent with Unique Peroxisome Proliferator-activated Receptor ${gamma}$ Binding Properties
J. Biol. Chem. 2008 283: 9168-9176. First Published on February 7, 2008; doi:10.1074/jbc.M800104200 [Abstract] [Full Text] [PDF]

Yutaka Harita, Hidetake Kurihara, Hidetaka Kosako, Tohru Tezuka, Takashi Sekine, Takashi Igarashi, and Seisuke Hattori: Neph1, a Component of the Kidney Slit Diaphragm, Is Tyrosine-phosphorylated by the Src Family Tyrosine Kinase and Modulates Intracellular Signaling by Binding to Grb2
J. Biol. Chem. 2008 283: 9177-9186. First Published on February 7, 2008; doi:10.1074/jbc.M707247200 [Abstract] [Full Text] [PDF]

Jose A. Chavez, William G. Roach, Susanna R. Keller, William S. Lane, and Gustav E. Lienhard: Inhibition of GLUT4 Translocation by Tbc1d1, a Rab GTPase-activating Protein Abundant in Skeletal Muscle, Is Partially Relieved by AMP-activated Protein Kinase Activation
J. Biol. Chem. 2008 283: 9187-9195. First Published on February 7, 2008; doi:10.1074/jbc.M708934200 [Abstract] [Full Text] [PDF]

Diana Hoogeboom, Marieke A. G. Essers, Paulien E. Polderman, Erik Voets, Lydia M. M. Smits, and Boudewijn M. Th. Burgering: Interaction of FOXO with β-Catenin Inhibits β-Catenin/T Cell Factor Activity
J. Biol. Chem. 2008 283: 9224-9230. First Published on February 4, 2008; doi:10.1074/jbc.M706638200 [Abstract] [Full Text] [PDF]

Cuiling Ma, Kimberly A. Bower, Gang Chen, Xianglin Shi, Zun-Ji Ke, and Jia Luo: Interaction between ERK and GSK3β Mediates Basic Fibroblast Growth Factor-induced Apoptosis in SK-N-MC Neuroblastoma Cells
J. Biol. Chem. 2008 283: 9248-9256. First Published on February 7, 2008; doi:10.1074/jbc.M707316200 [Abstract] [Full Text] [PDF]

Nobuhiro Suzuki, Sunil Bajad, Joel Shuman, Vladimir Shulaev, and Ron Mittler: The Transcriptional Co-activator MBF1c Is a Key Regulator of Thermotolerance in Arabidopsis thaliana
J. Biol. Chem. 2008 283: 9269-9275. First Published on January 17, 2008; doi:10.1074/jbc.M709187200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Christoforos Charalambous, Ingrid Gsandtner, Simon Keuerleber, Laura Milan-Lobo, Oliver Kudlacek, Michael Freissmuth, and Jürgen Zezula: Restricted Collision Coupling of the A_2A Receptor Revisited: EVIDENCE FOR PHYSICAL SEPARATION OF TWO SIGNALING CASCADES
J. Biol. Chem. 2008 283: 9276-9288. First Published on January 24, 2008; doi:10.1074/jbc.M706275200 [Abstract] [Full Text] [PDF]

Markus Höltje, Fred Hofmann, Romy Lux, Rüdiger W. Veh, Ingo Just, and Gudrun Ahnert-Hilger: Glutamate Uptake and Release by Astrocytes Are Enhanced by Clostridium botulinum C3 Protein
J. Biol. Chem. 2008 283: 9289-9299. First Published on January 30, 2008; doi:10.1074/jbc.M706499200 [Abstract] [Full Text] [PDF]

Yinghui Hu, Ingrid V. Lund, Maria C. Gravielle, David H. Farb, Amy R. Brooks-Kayal, and Shelley J. Russek: Surface Expression of GABA_A Receptors Is Transcriptionally Controlled by the Interplay of cAMP-response Element-binding Protein and Its Binding Partner Inducible cAMP Early Repressor
J. Biol. Chem. 2008 283: 9328-9340. First Published on January 7, 2008; doi:10.1074/jbc.M705110200 [Abstract] [Full Text] [PDF]

Toshio Ohta, Toshiaki Imagawa, and Shigeo Ito: Novel Gating and Sensitizing Mechanism of Capsaicin Receptor (TRPV1): TONIC INHIBITORY REGULATION OF EXTRACELLULAR SODIUM THROUGH THE EXTERNAL PROTONATION SITES ON TRPV1
J. Biol. Chem. 2008 283: 9377-9387. First Published on January 29, 2008; doi:10.1074/jbc.M709377200 [Abstract] [Full Text] [PDF] [Supplemental Data]

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DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

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Mechanisms Of Signal Transduction: