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On The Cover: The Φ6 icosahedral procapsid shell cut away to reveal molecules of the RNA-dependent RNA polymerase (red) placed in 3 of the 20 possible positions within the shell determined by cryo-electron microscopy. The background shows part of an electron micrograph of a field of Φ6 procapsid particles embedded in vitreous ice. For details see the article by Sen et al., pages 12227–12231.

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