JBC -- Table of Contents (Jun 6 2008, 283, (23))

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William L. Smith and Robert C. Murphy: Oxidized Lipids Formed Non-enzymatically by Reactive Oxygen Species
J. Biol. Chem. 2008 283: 15513-15514. First Published on February 19, 2008; doi:10.1074/jbc.R800006200 [Full Text] [PDF]

Bruce A. Freeman, Paul R. S. Baker, Francisco J. Schopfer, Steven R. Woodcock, Alessandra Napolitano, and Marco d'Ischia: Nitro-fatty Acid Formation and Signaling
J. Biol. Chem. 2008 283: 15515-15519. First Published on February 19, 2008; doi:10.1074/jbc.R800004200 [Full Text] [PDF] [Supplemental Data]

Robert C. Murphy and Kyle M. Johnson: Cholesterol, Reactive Oxygen Species, and the Formation of Biologically Active Mediators
J. Biol. Chem. 2008 283: 15521-15525. First Published on February 19, 2008; doi:10.1074/jbc.R700049200 [Full Text] [PDF]

Stanley L. Hazen: Oxidized Phospholipids as Endogenous Pattern Recognition Ligands in Innate Immunity
J. Biol. Chem. 2008 283: 15527-15531. First Published on February 19, 2008; doi:10.1074/jbc.R700054200 [Full Text] [PDF]

Ginger L. Milne, Huiyong Yin, and Jason D. Morrow: Human Biochemistry of the Isoprostane Pathway
J. Biol. Chem. 2008 283: 15533-15537. First Published on February 19, 2008; doi:10.1074/jbc.R700047200 [Full Text] [PDF]

Claus Schneider, Ned A. Porter, and Alan R. Brash: Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation
J. Biol. Chem. 2008 283: 15539-15543. First Published on February 19, 2008; doi:10.1074/jbc.R800001200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ian A. Blair: DNA Adducts with Lipid Peroxidation Products
J. Biol. Chem. 2008 283: 15545-15549. First Published on February 19, 2008; doi:10.1074/jbc.R700051200 [Full Text] [PDF]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Steven Raynard, Weixing Zhao, Wendy Bussen, Lucy Lu, Yang-Yang Ding, Valeria Busygina, Amom Ruhikanta Meetei, and Patrick Sung: Functional Role of BLAP75 in BLM-Topoisomerase III ${alpha}$ -dependent Holliday Junction Processing
J. Biol. Chem. 2008 283: 15701-15708. First Published on April 4, 2008; doi:10.1074/jbc.M802127200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hirotaka Ebina, Atreyi Ghatak Chatterjee, Robert L. Judson, and Henry L. Levin: The GP(Y/F) Domain of TF1 Integrase Multimerizes when Present in a Fragment, and Substitutions in This Domain Reduce Enzymatic Activity of the Full-length Protein
J. Biol. Chem. 2008 283: 15965-15974. First Published on April 8, 2008; doi:10.1074/jbc.M801354200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anthony J. Davis, Zhen Yan, Bobbie Martinez, and Marc C. Mumby: Protein Phosphatase 2A Is Targeted to Cell Division Control Protein 6 by a Calcium-binding Regulatory Subunit
J. Biol. Chem. 2008 283: 16104-16114. First Published on April 8, 2008; doi:10.1074/jbc.M710313200 [Abstract] [Full Text] [PDF] [ Supplemental Data]

Transcription, Chromatin, and Epigenetics:

Mary K. Bennett, Young-Kyo Seo, Shrimati Datta, Dong-Ju Shin, and Timothy F. Osborne: Selective Binding of Sterol Regulatory Element-binding Protein Isoforms and Co-regulatory Proteins to Promoters for Lipid Metabolic Genes in Liver
J. Biol. Chem. 2008 283: 15628-15637. First Published on April 15, 2008; doi:10.1074/jbc.M800391200 [Abstract] [Full Text] [PDF]

Khiem Tran and Jay D. Gralla: Control of the Timing of Promoter Escape and RNA Catalysis by the Transcription Factor IIB Fingertip
J. Biol. Chem. 2008 283: 15665-15671. First Published on April 14, 2008; doi:10.1074/jbc.M801439200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Patricia Respuela, Marcela Ferella, Alvaro Rada-Iglesias, and Lena Åslund: Histone Acetylation and Methylation at Sites Initiating Divergent Polycistronic Transcription in Trypanosoma cruzi
J. Biol. Chem. 2008 283: 15884-15892. First Published on April 9, 2008; doi:10.1074/jbc.M802081200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Alicia Palacios, Inés G. Muñoz, David Pantoja-Uceda, María J. Marcaida, Daniel Torres, José M. Martín-García, Irene Luque, Guillermo Montoya, and Francisco J. Blanco: Molecular Basis of Histone H3K4me3 Recognition by ING4
J. Biol. Chem. 2008 283: 15956-15964. First Published on April 1, 2008; doi:10.1074/jbc.M710020200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA-Mediated Regulation and Noncoding RNAs:

Amanda G. Oglesby, John M. Farrow, III, Joon-Hee Lee, Andrew P. Tomaras, E. P. Greenberg, Everett C. Pesci, and Michael L. Vasil: The Influence of Iron on Pseudomonas aeruginosa Physiology: A REGULATORY LINK BETWEEN IRON AND QUORUM SENSING
J. Biol. Chem. 2008 283: 15558-15567. First Published on April 18, 2008; doi:10.1074/jbc.M707840200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hongyan Wang, Animesh Ghosh, Huricha Baigude, Chao-shun Yang, Linghua Qiu, Xugang Xia, Hongxia Zhou, Tariq M. Rana, and Zuoshang Xu: Therapeutic Gene Silencing Delivered by a Chemically Modified Small Interfering RNA against Mutant SOD1 Slows Amyotrophic Lateral Sclerosis Progression
J. Biol. Chem. 2008 283: 15845-15852. First Published on March 26, 2008; doi:10.1074/jbc.M800834200 [Abstract] [Full Text] [PDF] [Summary]

Pasquale Fasanaro, Yuri D'Alessandra, Valeria Di Stefano, Roberta Melchionna, Sveva Romani, Giulio Pompilio, Maurizio C. Capogrossi, and Fabio Martelli: MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3
J. Biol. Chem. 2008 283: 15878-15883. First Published on April 16, 2008; doi:10.1074/jbc.M800731200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Salah E. Abdel-Ghany and Marinus Pilon: MicroRNA-mediated Systemic Down-regulation of Copper Protein Expression in Response to Low Copper Availability in Arabidopsis
J. Biol. Chem. 2008 283: 15932-15945. First Published on April 11, 2008; doi:10.1074/jbc.M801406200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translational Modification, and Degradation:

Ching-Hui Lin, Hung-Shu Chang, and Winston C. Y. Yu: USP11 Stabilizes HPV-16E7 and Further Modulates the E7 Biological Activity
J. Biol. Chem. 2008 283: 15681-15688. First Published on April 11, 2008; doi:10.1074/jbc.M708278200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mary MacPartlin, Shelya X. Zeng, and Hua Lu: Phosphorylation and Stabilization of TAp63 ${gamma}$ by I ${kappa}$ B Kinase-β
J. Biol. Chem. 2008 283: 15754-15761. First Published on April 14, 2008; doi:10.1074/jbc.M801394200 [Abstract] [Full Text] [PDF]

Abhay K. Singh, Maitrayee Bhattacharyya-Pakrasi, and Himadri B. Pakrasi: Identification of an Atypical Membrane Protein Involved in the Formation of Protein Disulfide Bonds in Oxygenic Photosynthetic Organisms
J. Biol. Chem. 2008 283: 15762-15770. First Published on April 15, 2008; doi:10.1074/jbc.M800982200 [Abstract] [Full Text] [PDF] [Supplemental Data]

M. Dean Chamberlain, Tim Chan, Jennifer C. Oberg, Andrea D. Hawrysh, Kristy M. James, Anurag Saxena, Jim Xiang, and Deborah H. Anderson: Disrupted RabGAP Function of the p85 Subunit of Phosphatidylinositol 3-Kinase Results in Cell Transformation
J. Biol. Chem. 2008 283: 15861-15868. First Published on April 3, 2008; doi:10.1074/jbc.M800941200 [Abstract] [Full Text] [PDF]

Richard S. Marshall, Nicholas A. Jolliffe, Aldo Ceriotti, Christopher J. Snowden, J. Michael Lord, Lorenzo Frigerio, and Lynne M. Roberts: The Role of CDC48 in the Retro-translocation of Non-ubiquitinated Toxin Substrates in Plant Cells
J. Biol. Chem. 2008 283: 15869-15877. First Published on April 17, 2008; doi:10.1074/jbc.M709316200 [Abstract] [Full Text] [PDF]

Adam L. Orr, Shanshan Huang, Meredith A. Roberts, John C. Reed, Shihua Li, and Xiao-Jiang Li: Sex-dependent Effect of BAG1 in Ameliorating Motor Deficits of Huntington Disease Transgenic Mice
J. Biol. Chem. 2008 283: 16027-16036. First Published on April 8, 2008; doi:10.1074/jbc.M710606200 [Abstract] [Full Text] [PDF] [ Supplemental Data]

Protein Structure and Folding:

Peter Bross, Søren Naundrup, Jakob Hansen, Marit Nyholm Nielsen, Jane Hvarregaard Christensen, Mogens Kruhøffer, Johan Palmfeldt, Thomas Juhl Corydon, Niels Gregersen, Debbie Ang, Costa Georgopoulos, and Kåre Lehmann Nielsen: The Hsp60-(p.V98I) Mutation Associated with Hereditary Spastic Paraplegia SPG13 Compromises Chaperonin Function Both in Vitro and in Vivo
J. Biol. Chem. 2008 283: 15694-15700. First Published on April 8, 2008; doi:10.1074/jbc.M800548200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jimmy Savistchenko, Joanna Krzewska, Nicolas Fay, and Ronald Melki: Molecular Chaperones and the Assembly of the Prion Ure2p in Vitro
J. Biol. Chem. 2008 283: 15732-15739. First Published on April 8, 2008; doi:10.1074/jbc.M800728200 [Abstract] [Full Text] [PDF]

Matthew W. Vetting, Patrick A. Frantom, and John S. Blanchard: Structural and Enzymatic Analysis of MshA from Corynebacterium glutamicum: SUBSTRATE-ASSISTED CATALYSIS
J. Biol. Chem. 2008 283: 15834-15844. First Published on April 4, 2008; doi:10.1074/jbc.M801017200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Elizabeth M. Baden, Barbara A. L. Owen, Francis C. Peterson, Brian F. Volkman, Marina Ramirez-Alvarado, and James R. Thompson: Altered Dimer Interface Decreases Stability in an Amyloidogenic Protein
J. Biol. Chem. 2008 283: 15853-15860. First Published on April 8, 2008; doi:10.1074/jbc.M705347200 [Abstract] [Full Text] [PDF] [ Supplemental Data]

Natallia Makarava and Ilia V. Baskakov: The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States
J. Biol. Chem. 2008 283: 15988-15996. First Published on April 8, 2008; doi:10.1074/jbc.M800562200 [Abstract] [Full Text] [PDF] [Supplemental Data]

James M. Pace, Mary Wiese, Andrea S. Drenguis, Natalia Kuznetsova, Sergey Leikin, Ulrike Schwarze, Diana Chen, Suzanne H. Mooney, Sheila Unger, and Peter H. Byers: Defective C-propeptides of the Pro ${alpha}$ 2(I) Chain of Type I Procollagen Impede Molecular Assembly and Result in Osteogenesis Imperfecta
J. Biol. Chem. 2008 283: 16061-16067. First Published on March 27, 2008; doi:10.1074/jbc.M801982200 [Abstract] [Full Text] [PDF]

Hong Wu, Jinrong Min, Hong Zeng, Diane E. McCloskey, Yoshihiko Ikeguchi, Peter Loppnau, Anthony J. Michael, Anthony E. Pegg, and Alexander N. Plotnikov: Crystal Structure of Human Spermine Synthase: IMPLICATIONS OF SUBSTRATE BINDING AND CATALYTIC MECHANISM
J. Biol. Chem. 2008 283: 16135-16146. First Published on March 26, 2008; doi:10.1074/jbc.M710323200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Tong-Lay Lau, Varun Dua, and Tobias S. Ulmer: Structure of the Integrin ${alpha}$ IIb Transmembrane Segment
J. Biol. Chem. 2008 283: 16162-16168. First Published on April 16, 2008; doi:10.1074/jbc.M801748200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xiaohang Cao, Svetlana V. Antonyuk, Sai V. Seetharaman, Lisa J. Whitson, Alexander B. Taylor, Stephen P. Holloway, Richard W. Strange, Peter A. Doucette, Joan Selverstone Valentine, Ashutosh Tiwari, Lawrence J. Hayward, Shelby Padua, Jeffrey A. Cohlberg, S. Samar Hasnain, and P. John Hart: Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis
J. Biol. Chem. 2008 283: 16169-16177. First Published on March 31, 2008; doi:10.1074/jbc.M801522200 [Abstract] [Full Text] [PDF]

Nathan P. Cowieson, Gordon King, David Cookson, Ian Ross, Thomas Huber, David A. Hume, Bostjan Kobe, and Jennifer L. Martin: Cortactin Adopts a Globular Conformation and Bundles Actin into Sheets
J. Biol. Chem. 2008 283: 16187-16193. First Published on March 27, 2008; doi:10.1074/jbc.M708917200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jette Wypych, Ming Li, Amy Guo, Zhongqi Zhang, Theresa Martinez, Martin J. Allen, Szilan Fodor, Drew N. Kelner, Gregory C. Flynn, Yaoqing Diana Liu, Pavel V. Bondarenko, Margaret Speed Ricci, Thomas M. Dillon, and Alain Balland: Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms
J. Biol. Chem. 2008 283: 16194-16205. First Published on March 13, 2008; doi:10.1074/jbc.M709987200 [Abstract] [Full Text] [PDF]

Thomas M. Dillon, Margaret Speed Ricci, Chris Vezina, Gregory C. Flynn, Yaoqing Diana Liu, Douglas S. Rehder, Matthew Plant, Brad Henkle, Yu Li, Songpon Deechongkit, Brian Varnum, Jette Wypych, Alain Balland, and Pavel V. Bondarenko: Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass
J. Biol. Chem. 2008 283: 16206-16215. First Published on March 12, 2008; doi:10.1074/jbc.M709988200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Noémi Fukuhara, Jason A. Howitt, Sadaf-Ahmahni Hussain, and Erhard Hohenester: Structural and Functional Analysis of Slit and Heparin Binding to Immunoglobulin-like Domains 1 and 2 of Drosophila Robo
J. Biol. Chem. 2008 283: 16226-16234. First Published on March 20, 2008; doi:10.1074/jbc.M800688200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Adam M. Cartwright, Eng-Kiat Lim, Colin Kleanthous, and Dianna J. Bowles: A Kinetic Analysis of Regiospecific Glucosylation by Two Glycosyltransferases of Arabidopsis thaliana: DOMAIN SWAPPING TO INTRODUCE NEW ACTIVITIES
J. Biol. Chem. 2008 283: 15724-15731. First Published on March 31, 2008; doi:10.1074/jbc.M801983200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Todd Green, Alexei Grigorian, Alla Klyuyeva, Alina Tuganova, Ming Luo, and Kirill M. Popov: Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2
J. Biol. Chem. 2008 283: 15789-15798. First Published on April 3, 2008; doi:10.1074/jbc.M800311200 [Abstract] [Full Text] [PDF]

Tao Pang, Zhen-Shan Zhang, Min Gu, Bei-Ying Qiu, Li-Fang Yu, Peng-Rong Cao, Wei Shao, Ming-Bo Su, Jing-Ya Li, Fa-Jun Nan, and Jia Li: Small Molecule Antagonizes Autoinhibition and Activates AMP-activated Protein Kinase in Cells
J. Biol. Chem. 2008 283: 16051-16060. First Published on March 5, 2008; doi:10.1074/jbc.M710114200 [Abstract] [Full Text] [PDF]

Yousong Ding, Robert M. Williams, and David H. Sherman: Molecular Analysis of a 4-Dimethylallyltryptophan Synthase from Malbranchea aurantiaca
J. Biol. Chem. 2008 283: 16068-16076. First Published on April 4, 2008; doi:10.1074/jbc.M801991200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lyudmila Yakovleva, Shengxi Chen, Sidney M. Hecht, and Stewart Shuman: Chemical and Traditional Mutagenesis of Vaccinia DNA Topoisomerase Provides Insights to Cleavage Site Recognition and Transesterification Chemistry
J. Biol. Chem. 2008 283: 16093-16103. First Published on March 25, 2008; doi:10.1074/jbc.M801595200 [Abstract] [Full Text] [PDF]

Xuying Liu, Alexander G. Pavlovsky, and Ronald E. Viola: The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase
J. Biol. Chem. 2008 283: 16216-16225. First Published on March 11, 2008; doi:10.1074/jbc.M800760200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Tomoyuki Nakatsubo, Masaharu Mizutani, Shiro Suzuki, Takefumi Hattori, and Toshiaki Umezawa: Characterization of Arabidopsis thaliana Pinoresinol Reductase, a New Type of Enzyme Involved in Lignan Biosynthesis
J. Biol. Chem. 2008 283: 15550-15557. First Published on March 17, 2008; doi:10.1074/jbc.M801131200 [Abstract] [Full Text] [PDF]

Hiroto Tanaka, Kazuaki Homma, Howard D. White, Toshio Yanagida, and Mitsuo Ikebe: Smooth Muscle Myosin Phosphorylated at Single Head Shows Sustained Mechanical Activity
J. Biol. Chem. 2008 283: 15611-15618. First Published on April 11, 2008; doi:10.1074/jbc.M710597200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Asadollah Aghaie, Christophe Lechaplais, Peggy Sirven, Sabine Tricot, Marielle Besnard-Gonnet, Delphine Muselet, Véronique de Berardinis, Annett Kreimeyer, Gabor Gyapay, Marcel Salanoubat, and Alain Perret: New Insights into the Alternative D-Glucarate Degradation Pathway
J. Biol. Chem. 2008 283: 15638-15646. First Published on March 25, 2008; doi:10.1074/jbc.M800487200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Susan N. Thomas, Fei Zhu, Ronald L. Schnaar, Christina S. Alves, and Konstantinos Konstantopoulos: Carcinoembryonic Antigen and CD44 Variant Isoforms Cooperate to Mediate Colon Carcinoma Cell Adhesion to E- and L-selectin in Shear Flow
J. Biol. Chem. 2008 283: 15647-15655. First Published on March 27, 2008; doi:10.1074/jbc.M800543200 [Abstract] [Full Text] [PDF]

L. Scott Forsberg and Russell W. Carlson: Structural Characterization of the Primary O-antigenic Polysaccharide of the Rhizobium leguminosarum 3841 Lipopolysaccharide and Identification of a New 3-Acetimidoylamino-3-deoxyhexuronic Acid Glycosyl Component: A UNIQUE O-METHYLATED GLYCAN OF UNIFORM SIZE, CONTAINING 6-DEOXY-3-O-METHYL-D-TALOSE, N-ACETYLQUINOVOSAMINE, AND RHIZOAMINURONIC ACID (3-ACETIMIDOYLAMINO-3-DEOXY-D-GLUCO-HEXURONIC ACID)
J. Biol. Chem. 2008 283: 16037-16050. First Published on April 2, 2008; doi:10.1074/jbc.M709615200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Matthew J. Stokes, M. Lucia S. Güther, Daniel C. Turnock, Alan R. Prescott, Kirstee L. Martin, Magnus S. Alphey, and Michael A. J. Ferguson: The Synthesis of UDP-N-acetylglucosamine Is Essential for Bloodstream Form Trypanosoma brucei in Vitro and in Vivo and UDP-N-acetylglucosamine Starvation Reveals a Hierarchy in Parasite Protein Glycosylation
J. Biol. Chem. 2008 283: 16147-16161. First Published on April 1, 2008; doi:10.1074/jbc.M709581200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling:

Ronald Carnemolla, Xuefeng Ren, Tapan K. Biswas, Stephen C. Meredith, Catherine A. Reardon, Jianjun Wang, and Godfrey S. Getz: The Specific Amino Acid Sequence between Helices 7 and 8 Influences the Binding Specificity of Human Apolipoprotein A-I for High Density Lipoprotein (HDL) Subclasses: A POTENTIAL FOR HDL PREFERENTIAL GENERATION
J. Biol. Chem. 2008 283: 15779-15788. First Published on April 1, 2008; doi:10.1074/jbc.M710244200 [Abstract] [Full Text] [PDF]

Maxime Denis, Yves D. Landry, and Xiaohui Zha: ATP-binding Cassette A1-mediated Lipidation of Apolipoprotein A-I Occurs at the Plasma Membrane and Not in the Endocytic Compartments
J. Biol. Chem. 2008 283: 16178-16186. First Published on April 1, 2008; doi:10.1074/jbc.M709597200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Qi Zong Lao, Evgeny Kobrinsky, Jo Beth Harry, Arippa Ravindran, and Nikolai M. Soldatov: New Determinant for the Ca_Vβ₂ Subunit Modulation of the Ca_V1.2 Calcium Channel
J. Biol. Chem. 2008 283: 15577-15588. First Published on April 14, 2008; doi:10.1074/jbc.M802035200 [Abstract] [Full Text] [PDF]

Gábor Czirják, Drazsen Vuity, and Péter Enyedi: Phosphorylation-dependent Binding of 14-3-3 Proteins Controls TRESK Regulation
J. Biol. Chem. 2008 283: 15672-15680. First Published on April 8, 2008; doi:10.1074/jbc.M800712200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Karl J. Erlandson, Eran Or, Andrew R. Osborne, and Tom A. Rapoport: Analysis of Polypeptide Movement in the SecY Channel during SecA-mediated Protein Translocation
J. Biol. Chem. 2008 283: 15709-15715. First Published on March 21, 2008; doi:10.1074/jbc.M710356200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Eirini Lionaki, Carine de Marcos Lousa, Catherine Baud, Maria Vougioukalaki, George Panayotou, and Kostas Tokatlidis: The Essential Function of Tim12 in Vivo Is Ensured by the Assembly Interactions of Its C-terminal Domain
J. Biol. Chem. 2008 283: 15747-15753. First Published on April 3, 2008; doi:10.1074/jbc.M800350200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Guillaume Duret, Michal Szymanski, Kyoung-Jae Choi, Hye-Jeong Yeo, and Anne H. Delcour: The TpsB Translocator HMW1B of Haemophilus influenzae Forms a Large Conductance Channel
J. Biol. Chem. 2008 283: 15771-15778. First Published on April 9, 2008; doi:10.1074/jbc.M708970200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yu-Young Kim, Do-Young Kim, Donghwan Shim, Won-Yong Song, Joohyun Lee, Julian I. Schroeder, Sanguk Kim, Nava Moran, and Youngsook Lee: Expression of the Novel Wheat Gene TM20 Confers Enhanced Cadmium Tolerance to Bakers' Yeast
J. Biol. Chem. 2008 283: 15893-15902. First Published on April 14, 2008; doi:10.1074/jbc.M708947200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chunlong Ma, Cinque S. Soto, Yuki Ohigashi, Albert Taylor, Vasilios Bournas, Brett Glawe, Maria K. Udo, William F. DeGrado, Robert A. Lamb, and Lawrence H. Pinto: Identification of the Pore-lining Residues of the BM2 Ion Channel Protein of Influenza B Virus
J. Biol. Chem. 2008 283: 15921-15931. First Published on April 11, 2008; doi:10.1074/jbc.M710302200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tzvi Tzubery, Abraham Rimon, and Etana Padan: Structure-based Functional Study Reveals Multiple Roles of Transmembrane Segment IX and Loop VIII–IX in NhaA Na⁺/H⁺ Antiporter of Escherichia coli at Physiological pH
J. Biol. Chem. 2008 283: 15975-15987. First Published on April 3, 2008; doi:10.1074/jbc.M800482200 [Abstract] [Full Text] [PDF]

W. R. A. Kosala J. S. Rajapaksha, Daoyi Wang, Jonathan N. Davies, Lina Chen, Gerald W. Zamponi, and Thomas E. Fisher: Novel Splice Variants of Rat Ca_V2.1 That Lack Much of the Synaptic Protein Interaction Site Are Expressed in Neuroendocrine Cells
J. Biol. Chem. 2008 283: 15997-16003. First Published on April 4, 2008; doi:10.1074/jbc.M710544200 [Abstract] [Full Text] [PDF]

Hamish Redmond Ross, Ian Napier, and Mark Connor: Inhibition of Recombinant Human T-type Calcium Channels by ${Delta}$ ⁹-Tetrahydrocannabinol and Cannabidiol
J. Biol. Chem. 2008 283: 16124-16134. First Published on April 7, 2008; doi:10.1074/jbc.M707104200 [Abstract] [Full Text] [PDF]

Martin Kolisek, Pierre Launay, Andreas Beck, Gerhard Sponder, Nicolas Serafini, Marcel Brenkus, Elisabeth Maria Froschauer, Holger Martens, Andrea Fleig, and Monika Schweigel: SLC41A1 Is a Novel Mammalian Mg²⁺ Carrier
J. Biol. Chem. 2008 283: 16235-16247. First Published on March 25, 2008; doi:10.1074/jbc.M707276200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Mikael S. Lindström and Yanping Zhang: Ribosomal Protein S9 Is a Novel B23/NPM-binding Protein Required for Normal Cell Proliferation
J. Biol. Chem. 2008 283: 15568-15576. First Published on April 17, 2008; doi:10.1074/jbc.M801151200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Peter G. Fuhrken, Pani A. Apostolidis, Stephan Lindsey, William M. Miller, and Eleftherios T. Papoutsakis: Tumor Suppressor Protein p53 Regulates Megakaryocytic Polyploidization and Apoptosis
J. Biol. Chem. 2008 283: 15589-15600. First Published on April 8, 2008; doi:10.1074/jbc.M801923200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ying Wai Chan, Kin Fan On, Wan Mui Chan, Winnie Wong, Ho On Siu, Pok Man Hau, and Randy Y. C. Poon: The Kinetics of p53 Activation Versus Cyclin E Accumulation Underlies the Relationship between the Spindle-assembly Checkpoint and the Postmitotic Checkpoint
J. Biol. Chem. 2008 283: 15716-15723. First Published on April 9, 2008; doi:10.1074/jbc.M800629200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Vicente A. Resto, Monica M. Burdick, Nilesh M. Dagia, Susan D. McCammon, Susan M. Fennewald, and Robert Sackstein: L-selectin-mediated Lymphocyte-Cancer Cell Interactions under Low Fluid Shear Conditions
J. Biol. Chem. 2008 283: 15816-15824. First Published on April 1, 2008; doi:10.1074/jbc.M708899200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gabriel E. Bertolesi, George Michaiel, and Sarah McFarlane: Two Heparanase Splicing Variants with Distinct Properties Are Necessary in Early Xenopus Development
J. Biol. Chem. 2008 283: 16004-16016. First Published on April 7, 2008; doi:10.1074/jbc.M708525200 [Abstract] [Full Text] [PDF]

Yutaka Maeda, Takuji Suzuki, Xiufang Pan, Gang Chen, Songqin Pan, Thomas Bartman, and Jeffrey A. Whitsett: CUL2 Is Required for the Activity of Hypoxia-inducible Factor and Vasculogenesis
J. Biol. Chem. 2008 283: 16084-16092. First Published on March 27, 2008; doi:10.1074/jbc.M710223200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Haeng Ran Seo, Joon Kim, Sangwoo Bae, Jae-Won Soh, and Yun-Sil Lee: Cdk5-mediated Phosphorylation of c-Myc on Ser-62 Is Essential in Transcriptional Activation of Cyclin B1 by Cyclin G1
J. Biol. Chem. 2008 283: 15601-15610. First Published on April 11, 2008; doi:10.1074/jbc.M800987200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Lifu Wang, Thurl E. Harris, and John C. Lawrence, Jr.: Regulation of Proline-rich Akt Substrate of 40 kDa (PRAS40) Function by Mammalian Target of Rapamycin Complex 1 (mTORC1)-mediated Phosphorylation
J. Biol. Chem. 2008 283: 15619-15627. First Published on March 27, 2008; doi:10.1074/jbc.M800723200 [Abstract] [Full Text] [PDF]

Gina N. Betts, Peter van der Geer, and Elizabeth A. Komives: Structural and Functional Consequences of Tyrosine Phosphorylation in the LRP1 Cytoplasmic Domain
J. Biol. Chem. 2008 283: 15656-15664. First Published on April 1, 2008; doi:10.1074/jbc.M709514200 [Abstract] [Full Text] [PDF]

Justin Hartupee, Xiaoxia Li, and Thomas Hamilton
: Interleukin 1 ${alpha}$ -induced NF ${kappa}$ B Activation and Chemokine mRNA Stabilization Diverge at IRAK1
J. Biol. Chem. 2008 283: 15689-15693. First Published on April 14, 2008; doi:10.1074/jbc.M801346200 [Abstract] [Full Text] [PDF] Faculty of 1000 *Recommended* - FREE!

Matthew Stuible, Nadia Dubé, and Michel L. Tremblay: PTP1B Regulates Cortactin Tyrosine Phosphorylation by Targeting Tyr⁴⁴⁶
J. Biol. Chem. 2008 283: 15740-15746. First Published on April 3, 2008; doi:10.1074/jbc.M710534200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yuriko Iwakura, Hiroyuki Nawa, Ichiro Sora, and Moses V. Chao: Dopamine D1 Receptor-induced Signaling through TrkB Receptors in Striatal Neurons
J. Biol. Chem. 2008 283: 15799-15806. First Published on April 1, 2008; doi:10.1074/jbc.M801553200 [Abstract] [Full Text] [PDF]

Ming-Tsan Lin, I-Hsin Kuo, Cheng-Chi Chang, Chia-Yu Chu, Hsing-Yu Chen, Been-Ren Lin, Munisamy Sureshbabu, Hou-Jung Shih, and Min-Liang Kuo: Involvement of Hypoxia-inducing Factor-1 ${alpha}$ -dependent Plasminogen Activator Inhibitor-1 Up-regulation in Cyr61/CCN1-induced Gastric Cancer Cell Invasion
J. Biol. Chem. 2008 283: 15807-15815. First Published on April 1, 2008; doi:10.1074/jbc.M708933200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ayaluru Murali, Xiaojun Li, C. T. Ranjith-Kumar, Kanchan Bhardwaj, Andreas Holzenburg, Pingwei Li, and C. Cheng Kao: Structure and Function of LGP2, a DEX(D/H) Helicase That Regulates the Innate Immunity Response
J. Biol. Chem. 2008 283: 15825-15833. First Published on April 14, 2008; doi:10.1074/jbc.M800542200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chun Guo and Alan J. Whitmarsh: The β-Arrestin-2 Scaffold Protein Promotes c-Jun N-terminal Kinase-3 Activation by Binding to Its Nonconserved N Terminus
J. Biol. Chem. 2008 283: 15903-15911. First Published on April 11, 2008; doi:10.1074/jbc.M710006200 [Abstract] [Full Text] [PDF]

Adam M. Wegner, Caroline A. Nebhan, Lan Hu, Devi Majumdar, Kristen M. Meier, Alissa M. Weaver, and Donna J. Webb: N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses
J. Biol. Chem. 2008 283: 15912-15920. First Published on April 21, 2008; doi:10.1074/jbc.M801555200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hyung-Ryong Kim, Geum-Hwa Lee, Ki-Chan Ha, Taeho Ahn, Ji-Yong Moon, Bong-Jin Lee, Ssang-Goo Cho, Sanguk Kim, Young-Rok Seo, Yong-Joo Shin, Soo-Wan Chae, John C. Reed, and Han-Jung Chae: Bax Inhibitor-1 Is a pH-dependent Regulator of Ca²⁺ Channel Activity in the Endoplasmic Reticulum
J. Biol. Chem. 2008 283: 15946-15955. First Published on March 31, 2008; doi:10.1074/jbc.M800075200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Wei Bin Fang, Dana M. Brantley-Sieders, Yoonha Hwang, Amy-Joan L. Ham, and Jin Chen: Identification and Functional Analysis of Phosphorylated Tyrosine Residues within EphA2 Receptor Tyrosine Kinase
J. Biol. Chem. 2008 283: 16017-16026. First Published on April 3, 2008; doi:10.1074/jbc.M709934200 [Abstract] [Full Text] [PDF]

Surinder M. Soond, Paul A. Townsend, Sean P. Barry, Richard A. Knight, David S. Latchman, and Anastasis Stephanou: ERK and the F-box Protein βTRCP Target STAT1 for Degradation
J. Biol. Chem. 2008 283: 16077-16083. First Published on March 31, 2008; doi:10.1074/jbc.M800384200 [Abstract] [Full Text] [PDF]

Bryan T. MacDonald, Chika Yokota, Keiko Tamai, Xin Zeng, and Xi He: Wnt Signal Amplification via Activity, Cooperativity, and Regulation of Multiple Intracellular PPPSP Motifs in the Wnt Co-receptor LRP6
J. Biol. Chem. 2008 283: 16115-16123. First Published on March 24, 2008; doi:10.1074/jbc.M800327200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Emilio Nogueira, Miguel Fidalgo, Arpad Molnar, John Kyriakis, Thomas Force, Juan Zalvide, and Celia M. Pombo: SOK1 Translocates from the Golgi to the Nucleus upon Chemical Anoxia and Induces Apoptotic Cell Death
J. Biol. Chem. 2008 283: 16248-16258. First Published on March 25, 2008; doi:10.1074/jbc.M709724200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mikihito Kajiya, Hideki Shiba, Tsuyoshi Fujita, Kazuhisa Ouhara, Katsuhiro Takeda, Noriyoshi Mizuno, Hiroyuki Kawaguchi, Masae Kitagawa, Takashi Takata, Koichiro Tsuji, and Hidemi Kurihara: Brain-derived Neurotrophic Factor Stimulates Bone/Cementum-related Protein Gene Expression in Cementoblasts
J. Biol. Chem. 2008 283: 16259-16267. First Published on April 3, 2008; doi:10.1074/jbc.M800668200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Linglin Xie, Yu Jiang, Ping Ouyang, Jie Chen, Hieu Doan, Betty Herndon, Jessica E. Sylvester, Ke Zhang, Agostino Molteni, Marie Reichle, Rongqing Zhang, Mark D. Haub, Richard C. Baybutt, and Weiqun Wang: Effects of dietary calorie restriction or exercise on the PI3K and Ras signaling pathways in the skin of mice. VOLUME 282 (2007) PAGES 28025-28035
J. Biol. Chem. 2008 283: 16268. [Full Text] [PDF]

Bernhard Knierim, Klaus Peter Hofmann, Wolfgang Gärtner, Wayne L. Hubbell, and Oliver P. Ernst: Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors. VOLUME 283 (2008) PAGES 4967-4974
J. Biol. Chem. 2008 283: 16268-a. [Full Text] [PDF]