JBC -- Table of Contents (Jun 20 2008, 283, (25))

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William M. Nauseef: Biological Roles for the NOX Family NADPH Oxidases
J. Biol. Chem. 2008 283: 16961-16965. First Published on April 17, 2008; doi:10.1074/jbc.R700045200 [Full Text] [PDF] [Supplemental Data]

Accelerated Publications:

Jason W. Upton, William J. Kaiser, and Edward S. Mocarski: Cytomegalovirus M45 Cell Death Suppression Requires Receptor-interacting Protein (RIP) Homotypic Interaction Motif (RHIM)-dependent Interaction with RIP1
J. Biol. Chem. 2008 283: 16966-16970. First Published on April 28, 2008; doi:10.1074/jbc.C800051200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Irina G. Minko, Michael B. Harbut, Ivan D. Kozekov, Albena Kozekova, Petra M. Jakobs, Susan B. Olson, Robb E. Moses, Thomas M. Harris, Carmelo J. Rizzo, and R. Stephen Lloyd: Role for DNA Polymerase ${kappa}$ in the Processing of N²-N²-Guanine Interstrand Cross-links
J. Biol. Chem. 2008 283: 17075-17082. First Published on April 22, 2008; doi:10.1074/jbc.M801238200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anna Travesa, Alba Duch, and David G. Quintana: Distinct Phosphatases Mediate the Deactivation of the DNA Damage Checkpoint Kinase Rad53
J. Biol. Chem. 2008 283: 17123-17130. First Published on April 25, 2008; doi:10.1074/jbc.M801402200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jennifer Scorah, Meng-Qiu Dong, John R. Yates, III, Mary Scott, David Gillespie, and Clare H. McGowan: A Conserved Proliferating Cell Nuclear Antigen-interacting Protein Sequence in Chk1 Is Required for Checkpoint Function
J. Biol. Chem. 2008 283: 17250-17259. First Published on April 30, 2008; doi:10.1074/jbc.M800369200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Phuong Pham, Marcus B. Smolka, Peter Calabrese, Alice Landolph, Ke Zhang, Huilin Zhou, and Myron F. Goodman: Impact of Phosphorylation and Phosphorylation-null Mutants on the Activity and Deamination Specificity of Activation-induced Cytidine Deaminase
J. Biol. Chem. 2008 283: 17428-17439. First Published on April 16, 2008; doi:10.1074/jbc.M802121200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Transcription, Chromatin, and Epigenetics:

Mathieu Gissot, Li-Min Ting, Thomas M. Daly, Lawrence W. Bergman, Photini Sinnis, and Kami Kim: High Mobility Group Protein HMGB2 Is a Critical Regulator of Plasmodium Oocyst Development
J. Biol. Chem. 2008 283: 17030-17038. First Published on April 8, 2008; doi:10.1074/jbc.M801637200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Joanna Towpik, Damian Graczyk, Anna Gajda, Olivier Lefebvre, and Magdalena Boguta: Derepression of RNA Polymerase III Transcription by Phosphorylation and Nuclear Export of Its Negative Regulator, Maf1
J. Biol. Chem. 2008 283: 17168-17174. First Published on April 29, 2008; doi:10.1074/jbc.M709157200 [Abstract] [Full Text] [PDF]

Andrei V. Chernov, Sergey A. Shiryaev, Alexander E. Aleshin, Boris I. Ratnikov, Jeffrey W. Smith, Robert C. Liddington, and Alex Y. Strongin: The Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 Helicase
J. Biol. Chem. 2008 283: 17270-17278. First Published on April 28, 2008; doi:10.1074/jbc.M801719200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Satoshi Fujii, Kosei Ito, Yoshiaki Ito, and Atsushi Ochiai: Enhancer of Zeste Homologue 2 (EZH2) Down-regulates RUNX3 by Increasing Histone H3 Methylation
J. Biol. Chem. 2008 283: 17324-17332. First Published on April 22, 2008; doi:10.1074/jbc.M800224200 [Abstract] [Full Text] [PDF] [Supplemental Data][Supplemental Data] AUTHOR'S CHOICE

RNA: Processing and Catalysis:

Gintaras Deikus, Ciarán Condon, and David H. Bechhofer: Role of Bacillus subtilis RNase J1 Endonuclease and 5'-Exonuclease Activities in trp Leader RNA Turnover
J. Biol. Chem. 2008 283: 17158-17167. First Published on April 29, 2008; doi:10.1074/jbc.M801461200 [Abstract] [Full Text] [PDF]

Felix Mueller-Planitz and Daniel Herschlag: Coupling between ATP Binding and DNA Cleavage by DNA Topoisomerase II: A UNIFYING KINETIC AND STRUCTURAL MECHANISM
J. Biol. Chem. 2008 283: 17463-17476. First Published on April 10, 2008; doi:10.1074/jbc.M710014200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA-Mediated Regulation and Noncoding RNAs:

Ahmed M. Wahid, Veronica K. Coventry, and Graeme L. Conn: Systematic Deletion of the Adenovirus-associated RNA_I Terminal Stem Reveals a Surprisingly Active RNA Inhibitor of Double-stranded RNA-activated Protein Kinase
J. Biol. Chem. 2008 283: 17485-17493. First Published on April 22, 2008; doi:10.1074/jbc.M802300200 [Abstract] [Full Text] [PDF] AUTHOR'S CHOICE

Protein Synthesis, Post-Translational Modification, and Degradation:

Ramiro E. Llovera, Matías de Tullio, Leonardo G. Alonso, Malcolm A. Leissring, Sergio B. Kaufman, Alex E. Roher, Gonzalo de Prat Gay, Laura Morelli, and Eduardo M. Castaño: The Catalytic Domain of Insulin-degrading Enzyme Forms a Denaturant-resistant Complex with Amyloid β Peptide: IMPLICATIONS FOR ALZHEIMER DISEASE PATHOGENESIS
J. Biol. Chem. 2008 283: 17039-17048. First Published on April 14, 2008; doi:10.1074/jbc.M706316200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Michael Reinartz, Zhaoping Ding, Ulrich Flögel, Axel Gödecke, and Jürgen Schrader: Nitrosative Stress Leads to Protein Glutathiolation, Increased S-Nitrosation, and Up-regulation of Peroxiredoxins in the Heart
J. Biol. Chem. 2008 283: 17440-17449. First Published on April 21, 2008; doi:10.1074/jbc.M800126200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anindita Bhoumik, Netai Singha, Matthew J. O'Connell, and Ze'ev A. Ronai: Regulation of TIP60 by ATF2 Modulates ATM Activation
J. Biol. Chem. 2008 283: 17605-17614. First Published on April 8, 2008; doi:10.1074/jbc.M802030200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Melania Apostolidou, Sajith A. Jayasinghe, and Ralf Langen: Structure of ${alpha}$ -Helical Membrane-bound Human Islet Amyloid Polypeptide and Its Implications for Membrane-mediated Misfolding
J. Biol. Chem. 2008 283: 17205-17210. First Published on April 28, 2008; doi:10.1074/jbc.M801383200 [Abstract] [Full Text] [PDF]

Guillaume A. Schoch, Jason K. Yano, Stefaan Sansen, Patrick M. Dansette, C. David Stout, and Eric F. Johnson: Determinants of Cytochrome P450 2C8 Substrate Binding: STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZONE, FELODIPINE, AND 9-CIS-RETINOIC ACID
J. Biol. Chem. 2008 283: 17227-17237. First Published on April 15, 2008; doi:10.1074/jbc.M802180200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Andrea Thorn, Claudia Egerer-Sieber, Christof M. Jäger, Vanessa Herl, Frieder Müller-Uri, Wolfgang Kreis, and Yves A. Muller: The Crystal Structure of Progesterone 5β-Reductase from Digitalis lanata Defines a Novel Class of Short Chain Dehydrogenases/Reductases
J. Biol. Chem. 2008 283: 17260-17269. First Published on November 21, 2007; doi:10.1074/jbc.M706185200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Thomas R. Jahn, Glenys A. Tennent, and Sheena E. Radford: A Common β-Sheet Architecture Underlies in Vitro and in Vivo β₂-Microglobulin Amyloid Fibrils
J. Biol. Chem. 2008 283: 17279-17286. First Published on April 18, 2008; doi:10.1074/jbc.M710351200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Sozanne R. N. Solmaz and Carola Hunte: Structure of Complex III with Bound Cytochrome c in Reduced State and Definition of a Minimal Core Interface for Electron Transfer
J. Biol. Chem. 2008 283: 17542-17549. First Published on April 4, 2008; doi:10.1074/jbc.M710126200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Maki Onda, Kazuyo Nakatani, Sayaka Takehara, Mika Nishiyama, Nobuyuki Takahashi, and Masaaki Hirose: Cleaved Serpin Refolds into the Relaxed State via a Stressed Conformer
J. Biol. Chem. 2008 283: 17568-17578. First Published on April 7, 2008; doi:10.1074/jbc.M709262200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Julia D. Burman, Elisa Leung, Karen L. Atkins, Maghnus N. O'Seaghdha, Lea Lango, Pau Bernadó, Stefan Bagby, Dmitri I. Svergun, Timothy J. Foster, David E. Isenman, and Jean M. H. van den Elsen: Interaction of Human Complement with Sbi, a Staphylococcal Immunoglobulin-binding Protein: INDICATIONS OF A NOVEL MECHANISM OF COMPLEMENT EVASION BY STAPHYLOCOCCUS AUREUS
J. Biol. Chem. 2008 283: 17579-17593. First Published on April 22, 2008; doi:10.1074/jbc.M800265200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Melanie J. Lewis, Mary Meehan, Peter Owen, and Jenny M. Woof: A Common Theme in Interaction of Bacterial Immunoglobulin-binding Proteins with Immunoglobulins Illustrated in the Equine System
J. Biol. Chem. 2008 283: 17615-17623. First Published on April 14, 2008; doi:10.1074/jbc.M709844200 [Abstract] [Full Text] [PDF] AUTHOR'S CHOICE

Kirsty L. Lightbody, Dariush Ilghari, Lorna C. Waters, Gemma Carey, Mark A. Bailey, Richard A. Williamson, Philip S. Renshaw, and Mark D. Carr: Molecular Features Governing the Stability and Specificity of Functional Complex Formation by Mycobacterium tuberculosis CFP-10/ESAT-6 Family Proteins
J. Biol. Chem. 2008 283: 17681-17690. First Published on April 21, 2008; doi:10.1074/jbc.M800123200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Eva Czirr, Barbara A. Cottrell, Stefanie Leuchtenberger, Thomas Kukar, Thomas B. Ladd, Hermann Esselmann, Sabine Paul, Robert Schubenel, Justin W. Torpey, Claus U. Pietrzik, Todd E. Golde, Jens Wiltfang, Karlheinz Baumann, Edward H. Koo, and Sascha Weggen: Independent Generation of Aβ42 and Aβ38 Peptide Species by ${gamma}$ -Secretase
J. Biol. Chem. 2008 283: 17049-17054. First Published on April 21, 2008; doi:10.1074/jbc.M802912200 [Abstract] [Full Text] [PDF]

Martina Schweiger, Gabriele Schoiswohl, Achim Lass, Franz P. W. Radner, Guenter Haemmerle, Roland Malli, Wolfgang Graier, Irina Cornaciu, Monika Oberer, Robert Salvayre, Judith Fischer, Rudolf Zechner, and Robert Zimmermann: The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding
J. Biol. Chem. 2008 283: 17211-17220. First Published on April 29, 2008; doi:10.1074/jbc.M710566200 [Abstract] [Full Text] [PDF]

Birthe Smolinsky, Sabrina A. Eichler, Sabine Buchmeier, Jochen C. Meier, and Guenter Schwarz: Splice-specific Functions of Gephyrin in Molybdenum Cofactor Biosynthesis
J. Biol. Chem. 2008 283: 17370-17379. First Published on April 14, 2008; doi:10.1074/jbc.M800985200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jin-Ah Cho, Pamela Osenkowski, Huiren Zhao, Seaho Kim, Marta Toth, Kristina Cole, Amro Aboukameel, Allen Saliganan, Lucia Schuger, R. Daniel Bonfil, and Rafael Fridman: The Inactive 44-kDa Processed Form of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Enhances Proteolytic Activity via Regulation of Endocytosis of Active MT1-MMP
J. Biol. Chem. 2008 283: 17391-17405. First Published on April 15, 2008; doi:10.1074/jbc.M708943200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Neil M. Kad, Kathleen M. Trybus, and David M. Warshaw: Load and P_i Control Flux through the Branched Kinetic Cycle of Myosin V
J. Biol. Chem. 2008 283: 17477-17484. First Published on April 27, 2008; doi:10.1074/jbc.M800539200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ghader Bashiri, Christopher J. Squire, Nicole J. Moreland, and Edward N. Baker: Crystal Structures of F₄₂₀-dependent Glucose-6-phosphate Dehydrogenase FGD1 Involved in the Activation of the Anti-tuberculosis Drug Candidate PA-824 Reveal the Basis of Coenzyme and Substrate Binding
J. Biol. Chem. 2008 283: 17531-17541. First Published on April 22, 2008; doi:10.1074/jbc.M801854200 [Abstract] [Full Text] [PDF]

Paul K. Fyfe, Sandra L. Oza, Alan H. Fairlamb, and William N. Hunter: Leishmania Trypanothione Synthetase-Amidase Structure Reveals a Basis for Regulation of Conflicting Synthetic and Hydrolytic Activities
J. Biol. Chem. 2008 283: 17672-17680. First Published on April 17, 2008; doi:10.1074/jbc.M801850200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Metabolism and Bioenergetics:

Miroslav Dostalek, Klarissa D. Hardy, Ginger L. Milne, Jason D. Morrow, Chi Chen, Frank J. Gonzalez, Jun Gu, Xinxin Ding, Delinda A. Johnson, Jeffrey A. Johnson, Martha V. Martin, and F. Peter Guengerich

: Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems
J. Biol. Chem. 2008 283: 17147-17157. First Published on April 28, 2008; doi:10.1074/jbc.M802447200 [Abstract] [Full Text] [PDF] [Supplemental Data] Faculty of 1000 *Must Read* - FREE! Faculty of 1000 *Must Read* - FREE!

Longxin Qiu, Xiaochun Wu, Jenny F. L. Chau, Irene Y. Y. Szeto, Wing Yip Tam, Zongsheng Guo, Sookja K. Chung, Peter J. Oates, Stephen S. M. Chung, and James Y. Yang: Aldose Reductase Regulates Hepatic Peroxisome Proliferator-activated Receptor ${alpha}$ Phosphorylation and Activity to Impact Lipid Homeostasis
J. Biol. Chem. 2008 283: 17175-17183. First Published on April 29, 2008; doi:10.1074/jbc.M801791200 [Abstract] [Full Text] [PDF]

Changhong Li, Itzhak Nissim, Pan Chen, Carol Buettger, Habiba Najafi, Yevgeny Daikhin, Ilana Nissim, Heather W. Collins, Marc Yudkoff, Charles A. Stanley, and Franz M. Matschinsky: Elimination of K_ATP Channels in Mouse Islets Results in Elevated [U-¹³C]Glucose Metabolism, Glutaminolysis, and Pyruvate Cycling but a Decreased ${gamma}$ -Aminobutyric Acid Shunt
J. Biol. Chem. 2008 283: 17238-17249. First Published on April 29, 2008; doi:10.1074/jbc.M709235200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Alison V. Nairn, William S. York, Kyle Harris, Erica M. Hall, J. Michael Pierce, and Kelley W. Moremen: Regulation of Glycan Structures in Animal Tissues: TRANSCRIPT PROFILING OF GLYCAN-RELATED GENES
J. Biol. Chem. 2008 283: 17298-17313. First Published on April 14, 2008; doi:10.1074/jbc.M801964200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Edward N. Harris, Janet A. Weigel, and Paul H. Weigel: The Human Hyaluronan Receptor for Endocytosis (HARE/Stabilin-2) Is a Systemic Clearance Receptor for Heparin
J. Biol. Chem. 2008 283: 17341-17350. First Published on April 22, 2008; doi:10.1074/jbc.M710360200 [Abstract] [Full Text] [PDF]

Lorna R. Fiedler, Elke Schönherr, Rachel Waddington, Stephan Niland, Daniela G. Seidler, Daniel Aeschlimann, and Johannes A. Eble: Decorin Regulates Endothelial Cell Motility on Collagen I through Activation of Insulin-like Growth Factor I Receptor and Modulation of ${alpha}$ 2β1 Integrin Activity
J. Biol. Chem. 2008 283: 17406-17415. First Published on April 14, 2008; doi:10.1074/jbc.M710025200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling:

Tibor Czabany, Andrea Wagner, Dagmar Zweytick, Karl Lohner, Erich Leitner, Elisabeth Ingolic, and Günther Daum: Structural and Biochemical Properties of Lipid Particles from the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2008 283: 17065-17074. First Published on April 22, 2008; doi:10.1074/jbc.M800401200 [Abstract] [Full Text] [PDF]

Alison A. Gardner, Ethan C. Reichert, Matthew K. Topham, and Diana M. Stafforini: Identification of a Domain That Mediates Association of Platelet-activating Factor Acetylhydrolase with High Density Lipoprotein
J. Biol. Chem. 2008 283: 17099-17106. First Published on April 22, 2008; doi:10.1074/jbc.M802394200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mária Simocková, Roman Holic, Dana Tahotná, Jana Patton-Vogt, and Peter Griac: Yeast Pgc1p (YPL206c) Controls the Amount of Phosphatidylglycerol via a Phospholipase C-type Degradation Mechanism
J. Biol. Chem. 2008 283: 17107-17115. First Published on April 23, 2008; doi:10.1074/jbc.M800868200 [Abstract] [Full Text] [PDF]

Heather C. Kuiper, Cristobal L. Miranda, John D. Sowell, and Jan F. Stevens: Mercapturic Acid Conjugates of 4-Hydroxy-2-nonenal and 4-Oxo-2-nonenal Metabolites Are in Vivo Markers of Oxidative Stress
J. Biol. Chem. 2008 283: 17131-17138. First Published on April 27, 2008; doi:10.1074/jbc.M802797200 [Abstract] [Full Text] [PDF]

Matthew R. Tubb, R. A. Gangani D. Silva, Jianwen Fang, Patrick Tso, and W. Sean Davidson: A Three-dimensional Homology Model of Lipid-free Apolipoprotein A-IV Using Cross-linking and Mass Spectrometry
J. Biol. Chem. 2008 283: 17314-17323. First Published on April 22, 2008; doi:10.1074/jbc.M800036200 [Abstract] [Full Text] [PDF]

Chinthaka Saneth Gangabadage, Janusz Zdunek, Marco Tessari, Solveig Nilsson, Gunilla Olivecrona, and Sybren Sipke Wijmenga: Structure and Dynamics of Human Apolipoprotein CIII
J. Biol. Chem. 2008 283: 17416-17427. First Published on April 11, 2008; doi:10.1074/jbc.M800756200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Eugeni V. Entchev, Dominik Schwudke, Vyacheslav Zagoriy, Vitali Matyash, Aliona Bogdanova, Bianca Habermann, Lin Zhu, Andrej Shevchenko, and Teymuras V. Kurzchalia: LET-767 Is Required for the Production of Branched Chain and Long Chain Fatty Acids in Caenorhabditis elegans
J. Biol. Chem. 2008 283: 17550-17560. First Published on April 4, 2008; doi:10.1074/jbc.M800965200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Catherine E. Clarke, Emma L. Veale, Ken Wyse, Jamie I. Vandenberg, and Alistair Mathie: The M1P1 Loop of TASK3 K2P Channels Apposes the Selectivity Filter and Influences Channel Function
J. Biol. Chem. 2008 283: 16985-16992. First Published on April 16, 2008; doi:10.1074/jbc.M801368200 [Abstract] [Full Text] [PDF]

Jiafu Wang, Jianghui Meng, Gary W. Lawrence, Tomas H. Zurawski, Astrid Sasse, MacDara O. Bodeker, Marcella A. Gilmore, Ester Fernández-Salas, Joseph Francis, Lance E. Steward, K. Roger Aoki, and J. Oliver Dolly: Novel Chimeras of Botulinum Neurotoxins A and E Unveil Contributions from the Binding, Translocation, and Protease Domains to Their Functional Characteristics
J. Biol. Chem. 2008 283: 16993-17002. First Published on April 8, 2008; doi:10.1074/jbc.M710442200 [Abstract] [Full Text] [PDF]

Chenguang Zhao, Winfried Haase, Robert Tampé, and Rupert Abele: Peptide Specificity and Lipid Activation of the Lysosomal Transport Complex ABCB9 (TAPL)
J. Biol. Chem. 2008 283: 17083-17091. First Published on April 22, 2008; doi:10.1074/jbc.M801794200 [Abstract] [Full Text] [PDF]

Heike Bauerschmitt, Soledad Funes, and Johannes M. Herrmann: The Membrane-bound GTPase Guf1 Promotes Mitochondrial Protein Synthesis under Suboptimal Conditions
J. Biol. Chem. 2008 283: 17139-17146. First Published on April 28, 2008; doi:10.1074/jbc.M710037200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Denis B. Tikhonov and Boris S. Zhorov: Molecular Modeling of Benzothiazepine Binding in the L-type Calcium Channel
J. Biol. Chem. 2008 283: 17594-17604. First Published on April 8, 2008; doi:10.1074/jbc.M800141200 [Abstract] [Full Text] [PDF]

Shenyuan L. Zhang, J. Ashot Kozak, Weihua Jiang, Andriy V. Yeromin, Jing Chen, Ying Yu, Aubin Penna, Wei Shen, Victor Chi, and Michael D. Cahalan: Store-dependent and -independent Modes Regulating Ca²⁺ Release-activated Ca²⁺ Channel Activity of Human Orai1 and Orai3
J. Biol. Chem. 2008 283: 17662-17671. First Published on April 17, 2008; doi:10.1074/jbc.M801536200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Julie Kniazeff, Lei Shi, Claus J. Loland, Jonathan A. Javitch, Harel Weinstein, and Ulrik Gether: An Intracellular Interaction Network Regulates Conformational Transitions in the Dopamine Transporter
J. Biol. Chem. 2008 283: 17691-17701. First Published on April 21, 2008; doi:10.1074/jbc.M800475200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Basis Of Cell and Developmental Biology:

Yukihiro Yamaguchi, Dennis Larkin, Roberto Lara-Lemus, Jose Ramos-Castañeda, Ming Liu, and Peter Arvan: Endoplasmic Reticulum (ER) Chaperone Regulation and Survival of Cells Compensating for Deficiency in the ER Stress Response Kinase, PERK
J. Biol. Chem. 2008 283: 17020-17029. First Published on April 21, 2008; doi:10.1074/jbc.M802466200 [Abstract] [Full Text] [PDF]

Ravi K. Gutti, Chon-Hwa Tsai-Morris, and Maria L. Dufau: Gonadotropin-regulated Testicular Helicase (DDX25), an Essential Regulator of Spermatogenesis, Prevents Testicular Germ Cell Apoptosis
J. Biol. Chem. 2008 283: 17055-17064. First Published on April 22, 2008; doi:10.1074/jbc.M708449200 [Abstract] [Full Text] [PDF] [Supplemental Data]

An-Sheng Zhang, Fan Yang, Kathrin Meyer, Catalina Hernandez, Tara Chapman-Arvedson, Pamela J. Bjorkman, and Caroline A. Enns: Neogenin-mediated Hemojuvelin Shedding Occurs after Hemojuvelin Traffics to the Plasma Membrane
J. Biol. Chem. 2008 283: 17494-17502. First Published on April 29, 2008; doi:10.1074/jbc.M710527200 [Abstract] [Full Text] [PDF]

SongXiao Xu, Catherine C. L. Wong, Edith H. Y. Tong, Stephen S. M. Chung, John R. Yates, III, YiBing Yin, and Ben C. B. Ko: Phosphorylation by Casein Kinase 1 Regulates Tonicity-induced Osmotic Response Element-binding Protein/Tonicity Enhancer-binding Protein Nucleocytoplasmic Trafficking
J. Biol. Chem. 2008 283: 17624-17634. First Published on April 14, 2008; doi:10.1074/jbc.M800281200 [Abstract] [Full Text] [PDF]

Huang-Ying Le, Yong Zhang, Han Liu, Li-Heng Ma, Yi Jin, Qiu-Hua Huang, Yi Chen, Min Deng, Zhu Chen, Sai-Juan Chen, and Ting Xi Liu: eena Promotes Myeloid Proliferation through Stimulating ERK1/2 Phosphorylation in Zebrafish
J. Biol. Chem. 2008 283: 17652-17661. First Published on April 15, 2008; doi:10.1074/jbc.M710517200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mingxing Ouyang, Shaoying Lu, Xiao-Yan Li, Jing Xu, Jihye Seong, Ben N. G. Giepmans, John Y.-J. Shyy, Stephen J. Weiss, and Yingxiao Wang: Visualization of Polarized Membrane Type 1 Matrix Metalloproteinase Activity in Live Cells by Fluorescence Resonance Energy Transfer Imaging
J. Biol. Chem. 2008 283: 17740-17748. First Published on April 25, 2008; doi:10.1074/jbc.M709872200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Claire A. Walshe, Stephen A. Beers, Ruth R. French, Claude H. T. Chan, Peter W. Johnson, Graham K. Packham, Martin J. Glennie, and Mark S. Cragg: Induction of Cytosolic Calcium Flux by CD20 Is Dependent upon B Cell Antigen Receptor Signaling
J. Biol. Chem. 2008 283: 16971-16984. First Published on April 21, 2008; doi:10.1074/jbc.M708459200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kenji Ichiyama, Hideyuki Yoshida, Yu Wakabayashi, Takatoshi Chinen, Kazuko Saeki, Mako Nakaya, Giichi Takaesu, Shohei Hori, Akihiko Yoshimura, and Takashi Kobayashi: Foxp3 Inhibits ROR ${gamma}$ t-mediated IL-17A mRNA Transcription through Direct Interaction with ROR ${gamma}$ t
J. Biol. Chem. 2008 283: 17003-17008. First Published on April 23, 2008; doi:10.1074/jbc.M801286200 [Abstract] [Full Text] [PDF] [Author Profile] [Summary]

Nazira Ozgen, Maria Obreztchikova, Jianfen Guo, Hasnae Elouardighi, Gerald W. Dorn, II, Brenda A. Wilson, and Susan F. Steinberg: Protein Kinase D Links G_q-coupled Receptors to cAMP Response Element-binding Protein (CREB)-Ser¹³³ Phosphorylation in the Heart
J. Biol. Chem. 2008 283: 17009-17019. First Published on March 31, 2008; doi:10.1074/jbc.M709851200 [Abstract] [Full Text] [PDF]

Wendy Ching, Howard C. Hang, and Roel Nusse: Lipid-independent Secretion of a Drosophila Wnt Protein
J. Biol. Chem. 2008 283: 17092-17098. First Published on April 22, 2008; doi:10.1074/jbc.M802059200 [Abstract] [Full Text] [PDF] AUTHOR'S CHOICE

Claire Thornton, Alessandro Sardini, and David Carling: Muscarinic Receptor Activation of AMP-activated Protein Kinase Inhibits Orexigenic Neuropeptide mRNA Expression
J. Biol. Chem. 2008 283: 17116-17122. First Published on April 24, 2008; doi:10.1074/jbc.M708987200 [Abstract] [Full Text] [PDF]

Wen-Ying Chen, Fang-Rong Chang, Zih-You Huang, Jyun-Hong Chen, Yang-Chang Wu, and Chin-Chung Wu: Tubocapsenolide A, a Novel Withanolide, Inhibits Proliferation and Induces Apoptosis in MDA-MB-231 Cells by Thiol Oxidation of Heat Shock Proteins
J. Biol. Chem. 2008 283: 17184-17193. First Published on April 28, 2008; doi:10.1074/jbc.M709447200 [Abstract] [Full Text] [PDF]

Eunice Y. Yuen, Qian Jiang, Paul Chen, Jian Feng, and Zhen Yan: Activation of 5-HT_2A/C Receptors Counteracts 5-HT_1A Regulation of N-Methyl-D-aspartate Receptor Channels in Pyramidal Neurons of Prefrontal Cortex
J. Biol. Chem. 2008 283: 17194-17204. First Published on April 28, 2008; doi:10.1074/jbc.M801713200 [Abstract] [Full Text] [PDF] AUTHOR'S CHOICE

Rachele Lipsky, Essie M. Potts, Sima T. Tarzami, Akil A. Puckerin, Joanne Stocks, Alison D. Schecter, Eric A. Sobie, Fadi G. Akar, and María A. Diversé-Pierluissi: β-Adrenergic Receptor Activation Induces Internalization of Cardiac Ca_v1.2 Channel Complexes through a β-Arrestin 1-mediated Pathway
J. Biol. Chem. 2008 283: 17221-17226. First Published on May 5, 2008; doi:10.1074/jbc.C800061200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mohammed Akhter Hossain, K. Johan Rosengren, Linda M. Haugaard-Jönsson, Soude Zhang, Sharon Layfield, Tania Ferraro, Norelle L. Daly, Geoffrey W. Tregear, John D. Wade, and Ross A. D. Bathgate: The A-chain of Human Relaxin Family Peptides Has Distinct Roles in the Binding and Activation of the Different Relaxin Family Peptide Receptors
J. Biol. Chem. 2008 283: 17287-17297. First Published on April 22, 2008; doi:10.1074/jbc.M801911200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Biswaranjan Pani, Hwei Ling Ong, Xibao Liu, Kristina Rauser, Indu S. Ambudkar, and Brij B. Singh: Lipid Rafts Determine Clustering of STIM1 in Endoplasmic Reticulum-Plasma Membrane Junctions and Regulation of Store-operated Ca²⁺ Entry (SOCE)
J. Biol. Chem. 2008 283: 17333-17340. First Published on April 22, 2008; doi:10.1074/jbc.M800107200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tamara I. A. Roach, Robert A. Rebres, Iain D. C. Fraser, Dianne L. DeCamp, Keng-Mean Lin, Paul C. Sternweis, Mel I. Simon, and William E. Seaman: Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium
J. Biol. Chem. 2008 283: 17351-17361. First Published on April 14, 2008; doi:10.1074/jbc.M800907200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Panu E. Kovanen, Jérôme Bernard, Amin Al-Shami, Chengyu Liu, Julie Bollenbacher-Reilley, Lynn Young, Cynthia Pise-Masison, Rosanne Spolski, and Warren J. Leonard: T-cell Development and Function Are Modulated by Dual Specificity Phosphatase DUSP5
J. Biol. Chem. 2008 283: 17362-17369. First Published on April 21, 2008; doi:10.1074/jbc.M709887200 [Abstract] [Full Text] [PDF] [Supplemental Data]

André Göhler, Guangming Xiong, Simone Paulsen, Gabriele Trentmann, and Edmund Maser: Testosterone-inducible Regulator Is a Kinase That Drives Steroid Sensing and Metabolism in Comamonas testosteroni
J. Biol. Chem. 2008 283: 17380-17390. First Published on April 17, 2008; doi:10.1074/jbc.M710166200 [Abstract] [Full Text] [PDF]

Lucas R. Jagemann, Luís G. Pérez-Rivas, E. Josué Ruiz, Juan A. Ranea, Francisca Sánchez-Jiménez, Ángel R. Nebreda, Emilio Alba, and José Lozano: The Functional Interaction of 14-3-3 Proteins with the ERK1/2 Scaffold KSR1 Occurs in an Isoform-specific Manner
J. Biol. Chem. 2008 283: 17450-17462. First Published on April 21, 2008; doi:10.1074/jbc.M709185200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jindong Xu, Manjula Weerapura, Mohammad K. Ali, Michael F. Jackson, Hongbin Li, Gang Lei, Sheng Xue, Chun L. Kwan, Morris F. Manolson, Kai Yang, John F. MacDonald, and Xian-Min Yu: Control of Excitatory Synaptic Transmission by C-terminal Src Kinase
J. Biol. Chem. 2008 283: 17503-17514. First Published on April 29, 2008; doi:10.1074/jbc.M800917200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Cyril Mionnet, Stéphanie Bogliolo, and Robert A. Arkowitz: Oligomerization Regulates the Localization of Cdc24, the Cdc42 Activator in Saccharomyces cerevisiae
J. Biol. Chem. 2008 283: 17515-17530. First Published on March 31, 2008; doi:10.1074/jbc.M800305200 [Abstract] [Full Text] [PDF]

Riad Efendiev, Claudia E. Budu, Alejandro M. Bertorello, and Carlos H. Pedemonte: G-protein-coupled Receptor-mediated Traffic of Na,K-ATPase to the Plasma Membrane Requires the Binding of Adaptor Protein 1 to a Tyr-255-based Sequence in the ${alpha}$ -Subunit
J. Biol. Chem. 2008 283: 17561-17567. First Published on April 17, 2008; doi:10.1074/jbc.M709260200 [Abstract] [Full Text] [PDF]

Lilly Y. W. Bourguignon, Karine Peyrollier, Weiliang Xia, and Eli Gilad: Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells
J. Biol. Chem. 2008 283: 17635-17651. First Published on April 25, 2008; doi:10.1074/jbc.M800109200 [Abstract] [Full Text] [PDF]

Kyoko Nakamura, Hiroshi Sakaue, Akihiko Nishizawa, Yasushi Matsuki, Hideyuki Gomi, Eijiro Watanabe, Ryuji Hiramatsua, Mimi Tamamori-Adachi, Shigetaka Kitajima, Tetsuo Noda, Wataru Ogawa, and Masato Kasuga: PDK1 Regulates Cell Proliferation and Cell Cycle Progression through Control of Cyclin D1 and p27^Kip1 Expression
J. Biol. Chem. 2008 283: 17702-17711. First Published on April 22, 2008; doi:10.1074/jbc.M802589200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Abhinav K. Jain, Shilpi Mahajan, and Anil K. Jaiswal: Phosphorylation and Dephosphorylation of Tyrosine 141 Regulate Stability and Degradation of INrf2: A NOVEL MECHANISM IN NRF2 ACTIVATION
J. Biol. Chem. 2008 283: 17712-17720. First Published on April 23, 2008; doi:10.1074/jbc.M709854200 [Abstract] [Full Text] [PDF]

Chengyong Shen, Yongfeng Chen, Huaqing Liu, Kejing Zhang, Ting Zhang, Anning Lin, and Naihe Jing: Hydrogen Peroxide Promotes Aβ Production through JNK-dependent Activation of ${gamma}$ -Secretase
J. Biol. Chem. 2008 283: 17721-17730. First Published on April 23, 2008; doi:10.1074/jbc.M800013200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Stephanie L. Lomonaco, Sarit Kahana, Michal Blass, Yehuda Brody, Hana Okhrimenko, Cunli Xiang, Susan Finniss, Peter M. Blumberg, Hae-Kyung Lee, and Chaya Brodie: Phosphorylation of Protein Kinase C ${delta}$ on Distinct Tyrosine Residues Induces Sustained Activation of Erk1/2 via Down-regulation of MKP-1: ROLE IN THE APOPTOTIC EFFECT OF ETOPOSIDE
J. Biol. Chem. 2008 283: 17731-17739. First Published on April 23, 2008; doi:10.1074/jbc.M801727200 [Abstract] [Full Text] [PDF]