JBC -- Table of Contents (Jul 11 2008, 283, (28))

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Reflections:

Osamu Hayaishi: From Oxygenase to Sleep
J. Biol. Chem. 2008 283: 19165-19175. First Published on April 4, 2008; doi:10.1074/jbc.X800002200 [Full Text] [PDF]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Hao Luo, Yehua Li, Jung-Jung Mu, Jinglan Zhang, Toru Tonaka, Yasuo Hamamori, Sung Yun Jung, Yi Wang, and Jun Qin: Regulation of Intra-S Phase Checkpoint by Ionizing Radiation (IR)-dependent and IR-independent Phosphorylation of SMC3
J. Biol. Chem. 2008 283: 19176-19183. First Published on April 28, 2008; doi:10.1074/jbc.M802299200 [Abstract] [Full Text] [PDF] [Author Profile][Supplemental Data] [Summary]

Naoko Kakusho, Chika Taniyama, and Hisao Masai: Identification of Stimulators and Inhibitors of Cdc7 Kinase in Vitro
J. Biol. Chem. 2008 283: 19211-19218. First Published on April 28, 2008; doi:10.1074/jbc.M803113200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Transcription, Chromatin, and Epigenetics:

Sandra A. S. Johnson, Louis Dubeau, and Deborah L. Johnson: Enhanced RNA Polymerase III-dependent Transcription Is Required for Oncogenic Transformation
J. Biol. Chem. 2008 283: 19184-19191. First Published on May 1, 2008; doi:10.1074/jbc.M802872200 [Abstract] [Full Text] [PDF] [Author Profile] [Summary]

Sabrina I. Houston, Kirk J. McManus, Melissa M. Adams, Jennifer K. Sims, Phillip B. Carpenter, Michael J. Hendzel, and Judd C. Rice: Catalytic Function of the PR-Set7 Histone H4 Lysine 20 Monomethyltransferase Is Essential for Mitotic Entry and Genomic Stability
J. Biol. Chem. 2008 283: 19478-19488. First Published on May 14, 2008; doi:10.1074/jbc.M710579200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Wolfgang Fischle, Henriette Franz, Steven A. Jacobs, C. David Allis, and Sepideh Khorasanizadeh: Specificity of the Chromodomain Y Chromosome Family of Chromodomains for Lysine-methylated ARK(S/T) Motifs
J. Biol. Chem. 2008 283: 19626-19635. First Published on May 1, 2008; doi:10.1074/jbc.M802655200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Processing and Catalysis:

Sreerama Shetty, Praveenkumar Shetty, Steven Idell, Thirunavukkarasu Velusamy, Yashodhar P. Bhandary, and Rashmi S. Shetty: Regulation of Plasminogen Activator Inhibitor-1 Expression by Tumor Suppressor Protein p53
J. Biol. Chem. 2008 283: 19570-19580. First Published on May 9, 2008; doi:10.1074/jbc.M710268200 [Abstract] [Full Text] [PDF]

Florian Heyd, Maria Carmo-Fonseca, and Tarik Möröy: Differential Isoform Expression and Interaction with the P32 Regulatory Protein Controls the Subcellular Localization of the Splicing Factor U2AF26
J. Biol. Chem. 2008 283: 19636-19645. First Published on May 6, 2008; doi:10.1074/jbc.M801014200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translational Modification, and Degradation:

Kai-Li He, Arunkumar B. Deora, Huabao Xiong, Qi Ling, Babette B. Weksler, Ruben Niesvizky, and Katherine A. Hajjar: Endothelial Cell Annexin A2 Regulates Polyubiquitination and Degradation of Its Binding Partner S100A10/p11
J. Biol. Chem. 2008 283: 19192-19200. First Published on April 23, 2008; doi:10.1074/jbc.M800100200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Crystal A. Miller, Heidi S. Leonard, Ivan G. Pinsky, Brandy M. Turner, Shervonda R. Williams, Leon Harrison, Jr., Ariane F. Fletcher, Gaozhong Shen, Donald A. Bryant, and Wendy M. Schluchter: Biogenesis of Phycobiliproteins: III. CpcM IS THE ASPARAGINE METHYLTRANSFERASE FOR PHYCOBILIPROTEIN β-SUBUNITS IN CYANOBACTERIA
J. Biol. Chem. 2008 283: 19293-19300. First Published on May 15, 2008; doi:10.1074/jbc.M802734200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jianping Jin, Xiaolu L. Ang, Xin Ye, Mark Livingstone, and J. Wade Harper: Differential Roles for Checkpoint Kinases in DNA Damage-dependent Degradation of the Cdc25A Protein Phosphatase
J. Biol. Chem. 2008 283: 19322-19328. First Published on May 13, 2008; doi:10.1074/jbc.M802474200 [Abstract] [Full Text] [PDF]

Kulandaivelu S. Vetrivel, Xulun Zhang, Xavier Meckler, Haipeng Cheng, Sungho Lee, Ping Gong, Kryslaine O. Lopes, Ying Chen, Nobuhisa Iwata, Ke-Jie Yin, Jin-Moo Lee, Angèle T. Parent, Takaomi C. Saido, Yue-Ming Li, Sangram S. Sisodia, and Gopal Thinakaran: Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ
J. Biol. Chem. 2008 283: 19489-19498. First Published on May 1, 2008; doi:10.1074/jbc.M801037200 [Abstract] [Full Text] [PDF] [Author Profile] [Summary]

Fiona L. Scott, Greg J. Fuchs, Sarah E. Boyd, Jean-Bernard Denault, Christine J. Hawkins, Franck Dequiedt, and Guy S. Salvesen: Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function
J. Biol. Chem. 2008 283: 19499-19510. First Published on May 5, 2008; doi:10.1074/jbc.M800331200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Francisca E. Reyes-Turcu, John R. Shanks, David Komander, and Keith D. Wilkinson: Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of Isopeptidase T
J. Biol. Chem. 2008 283: 19581-19592. First Published on May 15, 2008; doi:10.1074/jbc.M800947200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Becky M. Miller and Kathleen M. Trybus: Functional Effects of Nemaline Myopathy Mutations on Human Skeletal ${alpha}$ -Actin
J. Biol. Chem. 2008 283: 19379-19388. First Published on May 12, 2008; doi:10.1074/jbc.M801963200 [Abstract] [Full Text] [PDF]

Helga Kroschewski, Siew Pheng Lim, Rebecca E. Butcher, Thai Leong Yap, Julien Lescar, Peter J. Wright, Subhash G. Vasudevan, and Andrew D. Davidson: Mutagenesis of the Dengue Virus Type 2 NS5 Methyltransferase Domain
J. Biol. Chem. 2008 283: 19410-19421. First Published on May 9, 2008; doi:10.1074/jbc.M800613200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mihoko Ui, Yoshikazu Tanaka, Takeshi Tsumuraya, Ikuo Fujii, Masayuki Inoue, Masahiro Hirama, and Kouhei Tsumoto: How Protein Recognizes Ladder-like Polycyclic Ethers: INTERACTIONS BETWEEN CIGUATOXIN (CTX3C) FRAGMENTS AND ITS SPECIFIC ANTIBODY 10C9
J. Biol. Chem. 2008 283: 19440-19447. First Published on May 7, 2008; doi:10.1074/jbc.M801282200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mariana P. B. Gomes, Thiago A. Millen, Priscila S. Ferreira, Narcisa L. Cunha e Silva, Tuane C. R. G. Vieira, Marcius S. Almeida, Jerson L. Silva, and Yraima Cordeiro: Prion Protein Complexed to N2a Cellular RNAs through Its N-terminal Domain Forms Aggregates and Is Toxic to Murine Neuroblastoma Cells
J. Biol. Chem. 2008 283: 19616-19625. First Published on May 1, 2008; doi:10.1074/jbc.M802102200 [Abstract] [Full Text] [PDF] [Supplemental Data] AUTHOR'S CHOICE

Arindam Pal, Uyen B. Chu, Subramaniam Ramachandran, David Grawoig, Lian-Wang Guo, Abdol R. Hajipour, and Arnold E. Ruoho: Juxtaposition of the Steroid Binding Domain-like I and II Regions Constitutes a Ligand Binding Site in the ${sigma}$ -1 Receptor
J. Biol. Chem. 2008 283: 19646-19656. First Published on May 7, 2008; doi:10.1074/jbc.M802192200 [Abstract] [Full Text] [PDF]

Noriko Handa, Eiichi Mizohata, Seiichiro Kishishita, Mitsutoshi Toyama, Satoshi Morita, Tomomi Uchikubo-Kamo, Ryogo Akasaka, Kenji Omori, Jun Kotera, Takaho Terada, Mikako Shirouzu, and Shigeyuki Yokoyama: Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP
J. Biol. Chem. 2008 283: 19657-19664. First Published on May 13, 2008; doi:10.1074/jbc.M800595200 [Abstract] [Full Text] [PDF]

Andrea Spitaleri, Silvia Mari, Flavio Curnis, Catia Traversari, Renato Longhi, Claudio Bordignon, Angelo Corti, Gian-Paolo Rizzardi, and Giovanna Musco: Structural Basis for the Interaction of isoDGR with the RGD-binding Site of ${alpha}$ vβ3 Integrin
J. Biol. Chem. 2008 283: 19757-19768. First Published on May 13, 2008; doi:10.1074/jbc.M710273200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Carmen Michalski, Hoda Mohagheghi, Manfred Nimtz, Jacques Pasteels, and Dietrich Ober: Salicyl Alcohol Oxidase of the Chemical Defense Secretion of Two Chrysomelid Leaf Beetles: MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF TWO NEW MEMBERS OF THE GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE GENE FAMILY
J. Biol. Chem. 2008 283: 19219-19228. First Published on May 15, 2008; doi:10.1074/jbc.M802236200 [Abstract] [Full Text] [PDF]

Satoko Osawa, Satoru Funamoto, Mika Nobuhara, Satoko Wada-Kakuda, Masafumi Shimojo, Sosuke Yagishita, and Yasuo Ihara: Phosphoinositides Suppress ${gamma}$ -Secretase in Both the Detergent-soluble and -insoluble States
J. Biol. Chem. 2008 283: 19283-19292. First Published on May 14, 2008; doi:10.1074/jbc.M705954200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lianrui Chu, Yanlai Lai, Xiaoping Xu, Scott Eddy, Shuang Yang, Li Song, and David Kolodrubetz: A 52-kDa Leucyl Aminopeptidase from Treponema denticola Is a Cysteinylglycinase That Mediates the Second Step of Glutathione Metabolism
J. Biol. Chem. 2008 283: 19351-19358. First Published on May 15, 2008; doi:10.1074/jbc.M801034200 [Abstract] [Full Text] [PDF]

Päivi Tiainen, Annika Pasanen, Raija Sormunen, and Johanna Myllyharju: Characterization of Recombinant Human Prolyl 3-Hydroxylase Isoenzyme 2, an Enzyme Modifying the Basement Membrane Collagen IV
J. Biol. Chem. 2008 283: 19432-19439. First Published on May 15, 2008; doi:10.1074/jbc.M802973200 [Abstract] [Full Text] [PDF]

John P. Evans, Fernando Niemevz, Graciela Buldain, and Paul Ortiz de Montellano: Isoporphyrin Intermediate in Heme Oxygenase Catalysis: OXIDATION OF ${alpha}$ -MESO-PHENYLHEME
J. Biol. Chem. 2008 283: 19530-19539. First Published on May 16, 2008; doi:10.1074/jbc.M709685200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nashmil Emami, David Deperthes, Johan Malm, and Eleftherios P. Diamandis: Major Role of Human KLK14 in Seminal Clot Liquefaction
J. Biol. Chem. 2008 283: 19561-19569. First Published on May 15, 2008; doi:10.1074/jbc.M801194200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Robielyn P. Ilagan, Mauro Tiso, David W. Konas, Craig Hemann, Deborah Durra, Russ Hille, and Dennis J. Stuehr: Differences in a Conformational Equilibrium Distinguish Catalysis by the Endothelial and Neuronal Nitric-oxide Synthase Flavoproteins
J. Biol. Chem. 2008 283: 19603-19615. First Published on May 16, 2008; doi:10.1074/jbc.M802914200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Roxana A. Radu, Jane Hu, Jennifer Peng, Dean Bok, Nathan L. Mata, and Gabriel H. Travis: Retinal Pigment Epithelium-Retinal G Protein Receptor-Opsin Mediates Light-dependent Translocation of All-trans-retinyl Esters for Synthesis of Visual Chromophore in Retinal Pigment Epithelial Cells
J. Biol. Chem. 2008 283: 19730-19738. First Published on May 12, 2008; doi:10.1074/jbc.M801288200 [Abstract] [Full Text] [PDF]

Alexandra Tolia, Katrien Horré, and Bart De Strooper: Transmembrane Domain 9 of Presenilin Determines the Dynamic Conformation of the Catalytic Site of ${gamma}$ -Secretase
J. Biol. Chem. 2008 283: 19793-19803. First Published on May 15, 2008; doi:10.1074/jbc.M802461200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolism and Bioenergetics:

Sharon E. Malmberg and Christopher M. Adams: Insulin Signaling and the General Amino Acid Control Response: TWO DISTINCT PATHWAYS TO AMINO ACID SYNTHESIS AND UPTAKE
J. Biol. Chem. 2008 283: 19229-19234. First Published on May 14, 2008; doi:10.1074/jbc.M801331200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ana Castro, Catarina Lemos, Artur Falcão, N. Louise Glass, and Arnaldo Videira: Increased Resistance of Complex I Mutants to Phytosphingosine-induced Programmed Cell Death
J. Biol. Chem. 2008 283: 19314-19321. First Published on May 12, 2008; doi:10.1074/jbc.M802112200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Helena I. M. Boshoff, Xia Xu, Kapil Tahlan, Cynthia S. Dowd, Kevin Pethe, Luis R. Camacho, Tae-Ho Park, Chang-Soo Yun, Dirk Schnappinger, Sabine Ehrt, Kerstin J. Williams, and Clifton E. Barry, III: Biosynthesis and Recycling of Nicotinamide Cofactors in Mycobacterium tuberculosis: AN ESSENTIAL ROLE FOR NAD IN NONREPLICATING BACILLI
J. Biol. Chem. 2008 283: 19329-19341. First Published on May 19, 2008; doi:10.1074/jbc.M800694200 [Abstract] [Full Text] [PDF] [Supplementl Data]

Jean-François Coppin, Wei Qu, and Michael P. Waalkes: Interplay between Cellular Methyl Metabolism and Adaptive Efflux during Oncogenic Transformation from Chronic Arsenic Exposure in Human Cells
J. Biol. Chem. 2008 283: 19342-19350. First Published on May 16, 2008; doi:10.1074/jbc.M802942200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Stéphane Mesnage, Françoise Chau, Lionel Dubost, and Michel Arthur: Role of N-Acetylglucosaminidase and N-Acetylmuramidase Activities in Enterococcus faecalis Peptidoglycan Metabolism
J. Biol. Chem. 2008 283: 19845-19853. First Published on May 19, 2008; doi:10.1074/jbc.M802323200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Camilla Giudici, Nicolas Raynal, Hanna Wiedemann, Wayne A. Cabral, Joan C. Marini, Rupert Timpl, Hans Peter Bächinger, Richard W. Farndale, Takako Sasaki, and Ruggero Tenni: Mapping of SPARC/BM-40/Osteonectin-binding Sites on Fibrillar Collagens
J. Biol. Chem. 2008 283: 19551-19560. First Published on May 16, 2008; doi:10.1074/jbc.M710001200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling:

Thomas Thum and Jürgen Borlak: LOX-1 Receptor Blockade Abrogates oxLDL-induced Oxidative DNA Damage and Prevents Activation of the Transcriptional Repressor Oct-1 in Human Coronary Arterial Endothelium
J. Biol. Chem. 2008 283: 19456-19464. First Published on April 7, 2008; doi:10.1074/jbc.M708309200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Ronit Mor-Cohen, Nurit Rosenberg, Meytal Landau, Judith Lahav, and Uri Seligsohn: Specific Cysteines in β3 Are Involved in Disulfide Bond Exchange-dependent and -independent Activation of ${alpha}$ IIbβ3
J. Biol. Chem. 2008 283: 19235-19244. First Published on May 5, 2008; doi:10.1074/jbc.M802399200 [Abstract] [Full Text] [PDF]

Wayne I. DeHaven, Jeremy T. Smyth, Rebecca R. Boyles, Gary S. Bird, and James W. Putney, Jr.: Complex Actions of 2-Aminoethyldiphenyl Borate on Store-operated Calcium Entry
J. Biol. Chem. 2008 283: 19265-19273. First Published on May 16, 2008; doi:10.1074/jbc.M801535200 [Abstract] [Full Text] [PDF]

Jie Qi and Michael Forgac: Function and Subunit Interactions of the N-terminal Domain of Subunit a (Vph1p) of the Yeast V-ATPase
J. Biol. Chem. 2008 283: 19274-19282. First Published on May 20, 2008; doi:10.1074/jbc.M802442200 [Abstract] [Full Text] [PDF]

Matthew R. Livesey, Michelle A. Cooper, Tarek Z. Deeb, Jane E. Carland, Janna Kozuska, Tim. G. Hales, Jeremy J. Lambert, and John A. Peters: Structural Determinants of Ca²⁺ Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor
J. Biol. Chem. 2008 283: 19301-19313. First Published on May 12, 2008; doi:10.1074/jbc.M802406200 [Abstract] [Full Text] [PDF] AUTHOR'S CHOICE

Misaki Yamamoto, Satoru Unzai, Shinya Saijo, Kazuki Ito, Kenji Mizutani, Chiyo Suno-Ikeda, Yukako Yabuki-Miyata, Takaho Terada, Mitsutoshi Toyama, Mikako Shirouzu, Takuya Kobayashi, Yoshimi Kakinuma, Ichiro Yamato, Shigeyuki Yokoyama, So Iwata, and Takeshi Murata: Interaction and Stoichiometry of the Peripheral Stalk Subunits NtpE and NtpF and the N-terminal Hydrophilic Domain of NtpI of Enterococcus hirae V-ATPase
J. Biol. Chem. 2008 283: 19422-19431. First Published on May 6, 2008; doi:10.1074/jbc.M801772200 [Abstract] [Full Text] [PDF]

Asi Cohen, Yuval Ben-Abu, Shelly Hen, and Noam Zilberberg: A Novel Mechanism for Human K_2P2.1 Channel Gating: FACILITATION OF C-TYPE GATING BY PROTONATION OF EXTRACELLULAR HISTIDINE RESIDUES
J. Biol. Chem. 2008 283: 19448-19455. First Published on May 12, 2008; doi:10.1074/jbc.M801273200 [Abstract] [Full Text] [PDF]

Noushin Nabavi, Yulia Urukova, Marco Cardelli, Jane E. Aubin, and Rene E. Harrison: Lysosome Dispersion in Osteoblasts Accommodates Enhanced Collagen Production during Differentiation
J. Biol. Chem. 2008 283: 19678-19690. First Published on May 7, 2008; doi:10.1074/jbc.M802517200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sharad S. Singhal, Sushma Yadav, Kenneth Drake, Jyotsana Singhal, and Sanjay Awasthi: Hsf-1 and POB1 Induce Drug Sensitivity and Apoptosis by Inhibiting Ralbp1
J. Biol. Chem. 2008 283: 19714-19729. First Published on May 12, 2008; doi:10.1074/jbc.M708703200 [Abstract] [Full Text] [PDF]

Hindupur K. Anandatheerthavarada, Naresh Babu V. Sepuri, Gopa Biswas, and Narayan G. Avadhani: An Unusual TOM20/TOM22 Bypass Mechanism for the Mitochondrial Targeting of Cytochrome P450 Proteins Containing N-terminal Chimeric Signals
J. Biol. Chem. 2008 283: 19769-19780. First Published on May 14, 2008; doi:10.1074/jbc.M801464200 [Abstract] [Full Text] [PDF]

Eric Macia, Mariagrazia Partisani, Cyril Favard, Eva Mortier, Pascale Zimmermann, Marie-France Carlier, Pierre Gounon, Frédéric Luton, and Michel Franco: The Pleckstrin Homology Domain of the Arf6-specific Exchange Factor EFA6 Localizes to the Plasma Membrane by Interacting with Phosphatidylinositol 4,5-Bisphosphate and F-actin
J. Biol. Chem. 2008 283: 19836-19844. First Published on May 19, 2008; doi:10.1074/jbc.M800781200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Shuo Chen, Jelica Gluhak-Heinrich, Marcos Martinez, Tong Li, Yimin Wu, Hui-Hsiu Chuang, Lei Chen, Juan Dong, Isabel Gay, and Mary MacDougall: Bone Morphogenetic Protein 2 Mediates Dentin Sialophosphoprotein Expression and Odontoblast Differentiation via NF-Y Signaling
J. Biol. Chem. 2008 283: 19359-19370. First Published on April 18, 2008; doi:10.1074/jbc.M709492200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zhao Bo Li, Helen D. Kollias, and Kathryn R. Wagner: Myostatin Directly Regulates Skeletal Muscle Fibrosis
J. Biol. Chem. 2008 283: 19371-19378. First Published on May 3, 2008; doi:10.1074/jbc.M802585200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jennifer H. Cox, Richard A. Dean, Clive R. Roberts, and Christopher M. Overall: Matrix Metalloproteinase Processing of CXCL11/I-TAC Results in Loss of Chemoattractant Activity and Altered Glycosaminoglycan Binding
J. Biol. Chem. 2008 283: 19389-19399. First Published on April 14, 2008; doi:10.1074/jbc.M800266200 [Abstract] [Full Text] [PDF]

Noriaki Ono, Kazuhisa Nakashima, Susan R. Rittling, Ernestina Schipani, Tadayoshi Hayata, Kunimichi Soma, David T. Denhardt, Henry M. Kronenberg, Yoichi Ezura, and Masaki Noda: Osteopontin Negatively Regulates Parathyroid Hormone Receptor Signaling in Osteoblasts
J. Biol. Chem. 2008 283: 19400-19409. First Published on April 16, 2008; doi:10.1074/jbc.M800005200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Benny Björkblom, Jenni C. Vainio, Vesa Hongisto, Thomas Herdegen, Michael J. Courtney, and Eleanor T. Coffey: All JNKs Can Kill, but Nuclear Localization Is Critical for Neuronal Death
J. Biol. Chem. 2008 283: 19704-19713. First Published on May 12, 2008; doi:10.1074/jbc.M707744200 [Abstract] [Full Text] [PDF] [Supplemental Data]

David Allard, Nichola Figg, Martin R. Bennett, and Trevor D. Littlewood: Akt Regulates the Survival of Vascular Smooth Muscle Cells via Inhibition of FoxO3a and GSK3
J. Biol. Chem. 2008 283: 19739-19747. First Published on May 5, 2008; doi:10.1074/jbc.M710098200 [Abstract] [Full Text] [PDF]

Xiaoying Guo, Hiroko Oshima, Takanori Kitmura, Makoto M. Taketo, and Masanobu Oshima: Stromal Fibroblasts Activated by Tumor Cells Promote Angiogenesis in Mouse Gastric Cancer
J. Biol. Chem. 2008 283: 19864-19871. First Published on May 21, 2008; doi:10.1074/jbc.M800798200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Manuel Dehner, Michel Hadjihannas, Jörg Weiske, Otmar Huber, and Jürgen Behrens: Wnt Signaling Inhibits Forkhead Box O3a-induced Transcription and Apoptosis through Up-regulation of Serum- and Glucocorticoid-inducible Kinase 1
J. Biol. Chem. 2008 283: 19201-19210. First Published on May 16, 2008; doi:10.1074/jbc.M710366200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Todd D. Prickett, Jun Ninomiya-Tsuji, Peter Broglie, Tara L. Muratore-Schroeder, Jeffrey Shabanowitz, Donald F. Hunt, and David L. Brautigan: TAB4 Stimulates TAK1-TAB1 Phosphorylation and Binds Polyubiquitin to Direct Signaling to NF- ${kappa}$ B
J. Biol. Chem. 2008 283: 19245-19254. First Published on May 2, 2008; doi:10.1074/jbc.M800943200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ming-Chao Zhong and André Veillette: Control of T Lymphocyte Signaling by Ly108, a Signaling Lymphocytic Activation Molecule Family Receptor Implicated in Autoimmunity
J. Biol. Chem. 2008 283: 19255-19264. First Published on May 15, 2008; doi:10.1074/jbc.M800209200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Christoph Hintzen, Christina Evers, Barbara E. Lippok, Rudolf Volkmer, Peter C. Heinrich, Simone Radtke, and Heike M. Hermanns: Box 2 Region of the Oncostatin M Receptor Determines Specificity for Recruitment of Janus Kinases and STAT5 Activation
J. Biol. Chem. 2008 283: 19465-19477. First Published on April 22, 2008; doi:10.1074/jbc.M710157200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Douglas L. Sheridan, Yong Kong, Sirlester A. Parker, Kevin N. Dalby, and Benjamin E. Turk: Substrate Discrimination among Mitogen-activated Protein Kinases through Distinct Docking Sequence Motifs
J. Biol. Chem. 2008 283: 19511-19520. First Published on May 15, 2008; doi:10.1074/jbc.M801074200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Milica Momcilovic, Surtaj H. Iram, Yang Liu, and Marian Carlson: Roles of the Glycogen-binding Domain and Snf4 in Glucose Inhibition of SNF1 Protein Kinase
J. Biol. Chem. 2008 283: 19521-19529. First Published on May 12, 2008; doi:10.1074/jbc.M803624200 [Abstract] [Full Text] [PDF]

Irina Vetter, Wei Cheng, Madusha Peiris, Bruce D. Wyse, Sarah J. Roberts-Thomson, Jie Zheng, Gregory R. Monteith, and Peter J. Cabot: Rapid, Opioid-sensitive Mechanisms Involved in Transient Receptor Potential Vanilloid 1 Sensitization
J. Biol. Chem. 2008 283: 19540-19550. First Published on May 15, 2008; doi:10.1074/jbc.M707865200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shizhong Bu, Bagrat Kapanadze, Tien Hsu, and Maria Trojanowska: Opposite Effects of Dihydrosphingosine 1-Phosphate and Sphingosine 1-Phosphate on Transforming Growth Factor-β/Smad Signaling Are Mediated through the PTEN/PPM1A-dependent Pathway
J. Biol. Chem. 2008 283: 19593-19602. First Published on May 15, 2008; doi:10.1074/jbc.M802417200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jie Han, Wen Hou, Leslie A. Goldstein, Caisheng Lu, Donna B. Stolz, Xiao-Ming Yin, and Hannah Rabinowich: Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells
J. Biol. Chem. 2008 283: 19665-19677. First Published on March 28, 2008; doi:10.1074/jbc.M710169200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rahul Das, Mohammad T. Mazhab-Jafari, Somenath Chowdhury, Soumita SilDas, Rajeevan Selvaratnam, and Giuseppe Melacini: Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP
J. Biol. Chem. 2008 283: 19691-19703. First Published on April 14, 2008; doi:10.1074/jbc.M802164200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jian Huang, John M. Shelton, James A. Richardson, Kristine E. Kamm, and James T. Stull: Myosin Regulatory Light Chain Phosphorylation Attenuates Cardiac Hypertrophy
J. Biol. Chem. 2008 283: 19748-19756. First Published on May 12, 2008; doi:10.1074/jbc.M802605200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ammaji Rajala, Masaki Tanito, Yun Z. Le, C. Ronald Kahn, and Raju V. S. Rajala: Loss of Neuroprotective Survival Signal in Mice Lacking Insulin Receptor Gene in Rod Photoreceptor Cells
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Additions and Corrections:

Florian Gackière, Gabriel Bidaux, Philippe Delcourt, Fabien Van Coppenolle, Maria Katsogiannou, Etienne Dewailly, Alexis Bavencoffe, Myriam Tran Van Chuoï-Mariot, Brigitte Mauroy, Natalia Prevarskaya, and Pascal Mariot: CaV3.2 T-type calcium channels are involved in calcium-dependent secretion of neuroendocrine prostate cancer cells. VOLUME 283 (2008) PAGES 10162-10173
J. Biol. Chem. 2008 283: 19872. [Full Text] [PDF]