Some users of Journal of Biological Chemistry may find a consistency and reliability advantage in using a special private route to access the site. Journal of Biological Chemistry has made arrangements with a provider which offers an alternate network route through a global network serving 105 cities in 47 countries, encompassing the U.S., Canada, Latin America, Europe, the Middle East, Asia and the Pacific Rim. If you are experiencing trouble connecting to Journal of Biological Chemistry please try the alternate route instead to see if it provides you with better service.

To use the alternate route, go to http://intl.jbc.org

NOTE: If you go to http://intl.jbc.org and notice that it changes to http://www.jbc.org/ that means our system has automatically detected that you are using a very-high-speed research-network connection between Stanford University (where the Journal of Biological Chemistry server is located) and your organization. This network is called "Internet2" (or "Abilene"). Our server automatically uses that very-high-speed path instead of http://intl.jbc.org.

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What is http://intl.jbc.org ? Using this URL should make inconsistent web service good and consistent. It will not make already good and consistent web service necessarily any better.

Tips to Improve Speed:

• Look first at Abstracts, which usually arrive in about 1/10th the time of a full article, if you are not certain you want to see a full article. You can do this by clicking on the [Abstract] link in a table of contents or in a search result.
• Increase the size of the cache that your browser uses to save items that it has already seen. This will avoid returning to the server to get a symbol or a button that has already been seen before. You can change this in "Preferences/Advanced/Cache--Disk Cache".
• Change the "Page in cache..." (Mac) or "Document in cache..." (Windows) radio button in "Preferences/Advanced/Cache" to "Once per session". This will ensure a minimum number of inquiries to the server.
• Upgrade to the latest version of your browser. Each new version appears to have noticeable speed improvements, perhaps on the order of 20%.